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Cheap flights from Greenville, North Carolina to San Diego from $444

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville, North Carolina to San Diego departing on 4/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Greenville, North Carolina to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:03 pm - 10:59 pm
PGV
-
SAN
7h 56m
1 stop
American Airlines Logo
10:43 pm - 11:20 am
SAN
-
PGV
9h 37m
1 stop
$597American Airlines
Thu, Mar 26 - Mon, Mar 30
American Airlines Logo
12:54 pm - 8:33 pm
PGV
-
SAN
10h 39m
2 stops
American Airlines Logo
10:28 pm - 10:36 am
SAN
-
PGV
9h 08m
1 stop
$599American Airlines
Sat, May 16 - Wed, May 27
American Airlines Logo
12:54 pm - 8:33 pm
PGV
-
SAN
10h 39m
2 stops
American Airlines Logo
1:21 pm - 11:58 pm
SAN
-
PGV
7h 37m
1 stop
$602American Airlines
Sat, May 16 - Thu, May 28
American Airlines Logo
12:54 pm - 8:33 pm
PGV
-
SAN
10h 39m
2 stops
American Airlines Logo
8:05 am - 11:58 pm
SAN
-
PGV
12h 53m
2 stops
$604American Airlines
Sat, May 16 - Wed, May 27
American Airlines Logo
12:54 pm - 10:00 pm
PGV
-
SAN
12h 06m
2 stops
American Airlines Logo
10:28 pm - 10:36 am
SAN
-
PGV
9h 08m
1 stop
$622American Airlines
Sat, May 16 - Mon, May 25
American Airlines Logo
12:54 pm - 10:00 pm
PGV
-
SAN
12h 06m
2 stops
American Airlines Logo
4:22 pm - 10:36 am
SAN
-
PGV
15h 14m
2 stops
$636American Airlines
Sat, May 16 - Tue, May 26
American Airlines Logo
12:54 pm - 8:33 pm
PGV
-
SAN
10h 39m
2 stops
American Airlines Logo
4:22 pm - 10:36 am
SAN
-
PGV
15h 14m
2 stops
$639American Airlines
Sat, May 16 - Thu, May 28
American Airlines Logo
12:54 pm - 8:33 pm
PGV
-
SAN
10h 39m
2 stops
American Airlines Logo
6:25 am - 11:58 pm
SAN
-
PGV
14h 33m
2 stops
$678American Airlines
Sat, May 16 - Fri, May 29
American Airlines Logo
5:05 am - 11:09 am
PGV
-
SAN
9h 04m
1 stop
American Airlines Logo
10:28 pm - 10:36 am
SAN
-
PGV
9h 08m
1 stop
$680American Airlines
Sat, May 16 - Tue, May 26
American Airlines Logo
5:05 am - 11:09 am
PGV
-
SAN
9h 04m
1 stop
American Airlines Logo
1:21 pm - 11:58 pm
SAN
-
PGV
7h 37m
1 stop
$683American Airlines
Sat, May 16 - Thu, May 28

American Airlines flights from Greenville, North Carolina to San Diego

Our best American Airlines deals on Greenville, North Carolina to San Diego flight tickets
American Airlines
Mar 26
PGV6:03 pmPitt-Greenville
7h 56m
1 stop
SAN10:59 pmSan Diego
Mar 30
SAN10:43 pmSan Diego
9h 37m
1 stop
PGV11:20 amPitt-Greenville
$597
American Airlines
May 16
PGV12:54 pmPitt-Greenville
10h 39m
2 stops
SAN8:33 pmSan Diego
May 27
SAN10:28 pmSan Diego
9h 08m
1 stop
PGV10:36 amPitt-Greenville
$599
American Airlines
May 16
PGV12:54 pmPitt-Greenville
10h 39m
2 stops
SAN8:33 pmSan Diego
May 28
SAN1:21 pmSan Diego
7h 37m
1 stop
PGV11:58 pmPitt-Greenville
$602

momondo Fare Finder

 
Customize your flight search to find flights from Greenville, North Carolina to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Greenville, North Carolina to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Thu 3/26

6:03 pm-10:59 pm

1 stop7h 56m

San Diego

Mon 3/30

10:43 pm-11:20 am

1 stop9h 37m

$597

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Sat 5/16

12:54 pm-8:33 pm

2 stops10h 39m

San Diego

Wed 5/27

10:28 pm-10:36 am

1 stop9h 08m

$599

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Sat 5/16

12:54 pm-8:33 pm

2 stops10h 39m

San Diego

Thu 5/28

1:21 pm-11:58 pm

1 stop7h 37m

$602

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Sat 5/16

12:54 pm-8:33 pm

2 stops10h 39m

San Diego

Wed 5/27

8:05 am-11:58 pm

2 stops12h 53m

$604

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Sat 5/16

12:54 pm-10:00 pm

2 stops12h 06m

San Diego

Mon 5/25

10:28 pm-10:36 am

1 stop9h 08m

$622

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Sat 5/16

12:54 pm-10:00 pm

2 stops12h 06m

San Diego

Tue 5/26

4:22 pm-10:36 am

2 stops15h 14m

$636

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Sat 5/16

12:54 pm-8:33 pm

2 stops10h 39m

San Diego

Thu 5/28

4:22 pm-10:36 am

2 stops15h 14m

$639

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Sat 5/16

12:54 pm-8:33 pm

2 stops10h 39m

San Diego

Fri 5/29

6:25 am-11:58 pm

2 stops14h 33m

$678

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Sat 5/16

5:05 am-11:09 am

1 stop9h 04m

San Diego

Tue 5/26

10:28 pm-10:36 am

1 stop9h 08m

$680
Quickest round-trip

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Sat 5/16

5:05 am-11:09 am

1 stop9h 04m

San Diego

Thu 5/28

1:21 pm-11:58 pm

1 stop7h 37m

$683

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Greenville, North Carolina to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Pitt-Greenville to San Diego?

American Airlines is the most popular carrier operating from Pitt-Greenville to San Diego

What airlines fly to San Diego?

American Airlines, Southwest and Delta are the top three most popular airlines that fly to San Diego from Greenville, North Carolina according to our data. American Airlines is the first choice among our users, with 53% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 8 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

When to book flights from Greenville, North Carolina to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville, North Carolina to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville, North Carolina to San Diego (PGV to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville, North Carolina to San Diego

Fastest flight time

9h 12m

Direct flights

None
The fastest flight from Greenville, North Carolina to San Diego takes 9h 12m
There are no direct flights from Greenville, North Carolina to San Diego. There are no popular flight routes from Greenville, North Carolina to San Diego.
Search flight deals

  • How far is Pitt-Greenville to San Diego by plane?

    There are 2266.7 mi between Pitt-Greenville and San Diego. Flights usually cover this in 9h 12m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Pitt-Greenville Airport to San Diego Airport?

    Prices for flights from Pitt-Greenville Airport to San Diego Airport refresh daily.

  • How old do you have to be to fly from Pitt-Greenville Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Pitt-Greenville Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
Imperial Beach
La Mesa
San Ysidro
Borrego Springs
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Diego?

Finding the right flight to San Diego from Greenville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Greenville to San Diego with flexible booking policies on momondo?

Flights from Greenville to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Greenville to San Diego?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Greenville to San Diego.

I’m not ready to book a flight from Greenville to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Greenville and alert you when they change.

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