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Cheap flights from Greenville to San Francisco from $172

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to San Francisco departing on 3/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Greenville to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:03 am - 9:34 pm
GSP
-
SFO
14h 31m
1 stop
Multiple Airlines Logo
3:31 pm - 7:33 am
SFO
-
GSP
37h 02m
2 stops
$354Multiple Airlines
Mon, May 11 - Wed, May 20
Multiple Airlines Logo
10:03 am - 9:34 pm
GSP
-
SFO
14h 31m
1 stop
Multiple Airlines Logo
10:38 pm - 2:53 pm
SFO
-
GSP
37h 15m
2 stops
$361Multiple Airlines
Mon, May 11 - Tue, May 19
Multiple Airlines Logo
10:03 am - 9:34 pm
GSP
-
SFO
14h 31m
1 stop
Multiple Airlines Logo
9:33 pm - 3:43 pm
SFO
-
GSP
15h 10m
2 stops
$366Multiple Airlines
Mon, May 11 - Sun, May 17
Multiple Airlines Logo
10:03 am - 9:34 pm
GSP
-
SFO
14h 31m
1 stop
Multiple Airlines Logo
11:16 pm - 4:53 pm
SFO
-
GSP
14h 37m
2 stops
$367Multiple Airlines
Fri, May 8 - Sun, May 10
Multiple Airlines Logo
10:03 am - 9:34 pm
GSP
-
SFO
14h 31m
1 stop
Multiple Airlines Logo
5:47 pm - 1:18 pm
SFO
-
GSP
16h 31m
2 stops
$369Multiple Airlines
Mon, May 11 - Sat, May 16
American Airlines Logo
6:22 pm - 11:10 pm
GSP
-
SFO
7h 48m
1 stop
American Airlines Logo
11:30 pm - 10:19 am
SFO
-
GSP
7h 49m
1 stop
$373American Airlines
Sat, Apr 4 - Tue, Apr 7
American Airlines Logo
4:28 pm - 11:04 pm
GSP
-
SFO
9h 36m
1 stop
American Airlines Logo
5:23 am - 4:35 pm
SFO
-
GSP
8h 12m
1 stop
$379American Airlines
Sat, Apr 25 - Sat, May 23
American Airlines Logo
7:00 am - 1:15 pm
GSP
-
SFO
9h 15m
1 stop
American Airlines Logo
1:16 pm - 11:57 pm
SFO
-
GSP
7h 41m
1 stop
$382American Airlines
Wed, Apr 22 - Wed, Apr 29
United Airlines Logo
7:35 pm - 1:16 am
GSP
-
SFO
8h 41m
1 stop
United Airlines Logo
9:30 pm - 9:58 am
SFO
-
GSP
9h 28m
1 stop
$383United Airlines
Thu, May 14 - Tue, May 19
Southwest Logo
1:55 pm - 9:25 pm
GSP
-
SFO
10h 30m
1 stop
Southwest Logo
11:25 pm - 1:10 pm
SFO
-
GSP
10h 45m
2 stops
$384Southwest
Wed, Apr 15 - Mon, Apr 20

United Airlines flights from Greenville to San Francisco

Our best United Airlines deals on Greenville to San Francisco flight tickets
United Airlines
Apr 18
GSP7:42 pmGreenville
8h 35m
1 stop
SFO1:17 amSan Francisco
Apr 22
SFO10:38 pmSan Francisco
8h 17m
1 stop
GSP9:55 amGreenville
$383
United Airlines
Apr 7
GSP12:34 pmGreenville
9h 04m
1 stop
SFO6:38 pmSan Francisco
Apr 12
SFO10:38 pmSan Francisco
8h 17m
1 stop
GSP9:55 amGreenville
$413
United Airlines
Apr 6
GSP7:42 pmGreenville
8h 35m
1 stop
SFO1:17 amSan Francisco
Apr 10
SFO10:50 pmSan Francisco
9h 54m
1 stop
GSP11:44 amGreenville
$432

American Airlines flights from Greenville to San Francisco

Our best American Airlines deals on Greenville to San Francisco flight tickets
American Airlines
Apr 4
GSP6:22 pmGreenville
7h 48m
1 stop
SFO11:10 pmSan Francisco
Apr 7
SFO11:30 pmSan Francisco
7h 49m
1 stop
GSP10:19 amGreenville
$373
American Airlines
Apr 25
GSP4:28 pmGreenville
9h 36m
1 stop
SFO11:04 pmSan Francisco
May 23
SFO5:23 amSan Francisco
8h 12m
1 stop
GSP4:35 pmGreenville
$379
American Airlines
Apr 22
GSP7:00 amGreenville
9h 15m
1 stop
SFO1:15 pmSan Francisco
Apr 29
SFO1:16 pmSan Francisco
7h 41m
1 stop
GSP11:57 pmGreenville
$382

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Mon 5/11

10:03 am-9:34 pm

1 stop14h 31m

San Francisco

Wed 5/20

3:31 pm-7:33 am

2 stops37h 02m

$354

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Mon 5/11

10:03 am-9:34 pm

1 stop14h 31m

San Francisco

Tue 5/19

10:38 pm-2:53 pm

2 stops37h 15m

$361

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Mon 5/11

10:03 am-9:34 pm

1 stop14h 31m

San Francisco

Sun 5/17

9:33 pm-3:43 pm

2 stops15h 10m

$366

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Fri 5/8

10:03 am-9:34 pm

1 stop14h 31m

San Francisco

Sun 5/10

11:16 pm-4:53 pm

2 stops14h 37m

$367

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Mon 5/11

10:03 am-9:34 pm

1 stop14h 31m

San Francisco

Sat 5/16

5:47 pm-1:18 pm

2 stops16h 31m

$369
Quickest round-trip

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 4/4

6:22 pm-11:10 pm

1 stop7h 48m

San Francisco

Tue 4/7

11:30 pm-10:19 am

1 stop7h 49m

$373

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 4/25

4:28 pm-11:04 pm

1 stop9h 36m

San Francisco

Sat 5/23

5:23 am-4:35 pm

1 stop8h 12m

$379

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 4/22

7:00 am-1:15 pm

1 stop9h 15m

San Francisco

Wed 4/29

1:16 pm-11:57 pm

1 stop7h 41m

$382

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Thu 5/14

7:35 pm-1:16 am

1 stop8h 41m

San Francisco

Tue 5/19

9:30 pm-9:58 am

1 stop9h 28m

$383

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 4/15

1:55 pm-9:25 pm

1 stop10h 30m

San Francisco

Mon 4/20

11:25 pm-1:10 pm

2 stops10h 45m

$384

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Greenville to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of August, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $429.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $498 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Greenville for as low as $312 on momondo.

How have Greenville to San Francisco flight prices changed over time?

As of March 2026, prices for Greenville to San Francisco flights are approximately 2% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to San Francisco (GSP to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Francisco

Fastest flight time

7h 06m

Direct flights

None
The fastest flight from Greenville to San Francisco takes 7h 06m
There are no direct flights from Greenville to San Francisco. There are no popular flight routes from Greenville to San Francisco.
Search flight deals

  • How far is Greenville to San Francisco by plane?

    San Francisco is 2218.5 mi away from Greenville. A reasonable flight in good conditions will take 7h 06m.

  • When did momondo last update prices for flights from Greenville Airport to San Francisco Airport?

    Prices for flights from Greenville Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to San Francisco Airport?

  • How old do you have to be to fly from Greenville Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents you'll need for your trip to San Francisco Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to San Francisco?

Best airlines flying from Greenville to San Francisco

Compare and see reviews for airlines that fly from Greenville to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $276Free CancellationRating
7.9
8,276 reviews
Search Delta flights
United AirlinesPriceFrom $311Free CancellationRating
7.4
9,409 reviews
Search United Airlines flights
SouthwestPriceFrom $330Free CancellationRating
8.0
4,317 reviews
Search Southwest flights
American AirlinesPriceFrom $331Free CancellationRating
7.1
11,414 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Walnut Creek
Hayward
Berkeley
Santa Clara
Big Sur
Fremont
Calistoga
Vallejo
Salinas
Half Moon Bay
Daly City
South San Francisco
Pacific Grove
Milpitas

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to San Francisco for you.

Can I find flights from Greenville to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to San Francisco?

momondo helps you find the best flight between Greenville and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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