Cheap flights from Greenville to San Francisco from $167

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to San Francisco departing on 9/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

American Airlines Logo
2:35 pm - 8:29 pmGSP-SFO
8h 54m1 stop
American Airlines Logo
7:00 am - 4:49 pmSFO-GSP
6h 49m1 stop
$331American Airlines
Find Deal
Sat, Aug 23 - Sat, Aug 30
American Airlines Logo
4:17 pm - 8:29 pmGSP-SFO
7h 12m1 stop
American Airlines Logo
5:45 am - 4:49 pmSFO-GSP
8h 04m1 stop
$332American Airlines
Find Deal
Sat, Aug 23 - Sat, Aug 30
Delta Logo
6:00 am - 10:16 amGSP-SFO
7h 16m1 stop
Delta Logo
10:45 pm - 10:31 amSFO-GSP
8h 46m1 stop
$333Delta
Find Deal
Sat, Nov 8 - Sat, Dec 6
American Airlines Logo
7:00 am - 12:15 pmGSP-SFO
8h 15m1 stop
American Airlines Logo
6:30 am - 6:26 pmSFO-GSP
8h 56m2 stops
$336American Airlines
Find Deal
Sat, Aug 23 - Sat, Aug 30
American Airlines Logo
7:14 am - 2:16 pmGSP-SFO
10h 02m1 stop
American Airlines Logo
6:30 am - 6:26 pmSFO-GSP
8h 56m2 stops
$337American Airlines
Find Deal
Sat, Aug 23 - Sat, Aug 30
Southwest Logo
1:40 pm - 8:20 pmGSP-SFO
9h 40m2 stops
Southwest Logo
9:25 pm - 9:45 amSFO-GSP
9h 20m1 stop
$338Southwest
Find Deal
Sat, Nov 8 - Sat, Dec 6
Southwest Logo
1:40 pm - 8:20 pmGSP-SFO
9h 40m2 stops
Southwest Logo
12:35 pm - 9:45 amSFO-GSP
18h 10m2 stops
$349Southwest
Find Deal
Sat, Nov 8 - Sat, Dec 6
Delta Logo
4:35 pm - 8:28 pmGSP-SFO
6h 53m1 stop
Delta Logo
10:50 pm - 8:59 amSFO-GSP
7h 09m1 stop
$410Delta
Find Deal
Fri, Oct 3 - Sun, Oct 5
United Airlines Logo
6:02 am - 11:13 amGSP-SFO
8h 11m1 stop
United Airlines Logo
9:15 pm - 8:51 amSFO-GSP
8h 36m1 stop
$437United Airlines
Find Deal
Mon, Aug 25 - Thu, Aug 28
United Airlines Logo
6:08 am - 1:54 pmGSP-SFO
10h 46m1 stop
United Airlines Logo
5:15 am - 4:53 pmSFO-GSP
8h 38m1 stop
$459United Airlines
Find Deal
Thu, Aug 21 - Mon, Aug 25

American Airlines flights from Greenville to San Francisco

Our best American Airlines deals on Greenville to San Francisco flight tickets
American Airlines
Aug 23
GSP2:35 pmGreenville
8h 54m
1 stop
SFO8:29 pmSan Francisco
Aug 30
SFO7:00 amSan Francisco
6h 49m
1 stop
GSP4:49 pmGreenville
American Airlines
Aug 23
GSP4:17 pmGreenville
7h 12m
1 stop
SFO8:29 pmSan Francisco
Aug 30
SFO5:45 amSan Francisco
8h 04m
1 stop
GSP4:49 pmGreenville
American Airlines
Aug 23
GSP7:00 amGreenville
8h 15m
1 stop
SFO12:15 pmSan Francisco
Aug 30
SFO6:30 amSan Francisco
8h 56m
2 stops
GSP6:26 pmGreenville

United Airlines flights from Greenville to San Francisco

Our best United Airlines deals on Greenville to San Francisco flight tickets
United Airlines
Aug 25
GSP6:02 amGreenville
8h 11m
1 stop
SFO11:13 amSan Francisco
Aug 28
SFO9:15 pmSan Francisco
8h 36m
1 stop
GSP8:51 amGreenville
United Airlines
Aug 21
GSP6:08 amGreenville
10h 46m
1 stop
SFO1:54 pmSan Francisco
Aug 25
SFO5:15 amSan Francisco
8h 38m
1 stop
GSP4:53 pmGreenville
United Airlines
Sep 4
GSP5:34 pmGreenville
9h 25m
1 stop
SFO11:59 pmSan Francisco
Sep 7
SFO11:59 pmSan Francisco
8h 57m
1 stop
GSP11:56 amGreenville

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 8/23

2:35 pm-8:29 pm

1 stop8h 54m

San Francisco

Sat 8/30

7:00 am-4:49 pm

1 stop6h 49m

$331

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 8/23

4:17 pm-8:29 pm

1 stop7h 12m

San Francisco

Sat 8/30

5:45 am-4:49 pm

1 stop8h 04m

$332

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 11/8

6:00 am-10:16 am

1 stop7h 16m

San Francisco

Sat 12/6

10:45 pm-10:31 am

1 stop8h 46m

$333

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 8/23

7:00 am-12:15 pm

1 stop8h 15m

San Francisco

Sat 8/30

6:30 am-6:26 pm

2 stops8h 56m

$336

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 8/23

7:14 am-2:16 pm

1 stop10h 02m

San Francisco

Sat 8/30

6:30 am-6:26 pm

2 stops8h 56m

$337

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 11/8

1:40 pm-8:20 pm

2 stops9h 40m

San Francisco

Sat 12/6

9:25 pm-9:45 am

1 stop9h 20m

$338

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 11/8

1:40 pm-8:20 pm

2 stops9h 40m

San Francisco

Sat 12/6

12:35 pm-9:45 am

2 stops18h 10m

$349

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Fri 10/3

4:35 pm-8:28 pm

1 stop6h 53m

San Francisco

Sun 10/5

10:50 pm-8:59 am

1 stop7h 09m

$410

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Mon 8/25

6:02 am-11:13 am

1 stop8h 11m

San Francisco

Thu 8/28

9:15 pm-8:51 am

1 stop8h 36m

$437

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Thu 8/21

6:08 am-1:54 pm

1 stop10h 46m

San Francisco

Mon 8/25

5:15 am-4:53 pm

1 stop8h 38m

$459

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Greenville to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of August, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $398.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Greenville to San Francisco is on a Wednesday when prices can be found for as low as $419. The most expensive day to fly to San Francisco is Thursday, with ticket prices averaging around $575.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Greenville to San Francisco flights are usually those with departure times at noon. Our users have found flights to San Francisco at noon for as low as $498. Flights in the afternoon are often more expensive with an average ticket price of $528.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $465 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Greenville for as low as $340 on momondo.

How have Greenville to San Francisco flight prices changed over time?

As of July 2025, prices for Greenville to San Francisco flights are approximately 27% cheaper when compared to flights at the same time last year.

When to book flights from Greenville to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to San Francisco (GSP to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Francisco

Best Price Found

$167

Fastest flight time

6h 53m

Direct flights

None

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from Greenville in the past 72 hours is $167. The best round-trip flight deal from Greenville to San Francisco found on momondo in the last 72 hours is $331.
The fastest flight from Greenville to San Francisco takes 6h 53m
There are no direct flights from Greenville to San Francisco. Popular non-direct route for this connection is Greenville Airport - San Francisco Airport.
There is 1 airport near San Francisco: San Francisco (SFO)

  • How far is Greenville to San Francisco by plane?

    San Francisco is 2218.5 mi away from Greenville. A reasonable flight in good conditions will take 6h 53m.

  • When did momondo last update prices for flights from Greenville Airport to San Francisco Airport?

    Prices for flights from Greenville Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to San Francisco Airport?

  • How old do you have to be to fly from Greenville Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents you'll need for your trip to San Francisco Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Greenville to San Francisco?

  • What is the most popular airline from Greenville to San Francisco?


Best airlines flying from Greenville to San Francisco

Compare and see reviews for airlines that fly from Greenville to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $312Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights
DeltaPriceFrom $326Free CancellationRating
8.0
7,981 reviews
Search Delta flights
American AirlinesPriceFrom $337Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $366Free CancellationRating
8.0
4,246 reviews
Search Southwest flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Calistoga
Hayward
Bodega Bay
Sonoma
Roseville
Santa Clara
Big Sur
Daly City
Berkeley
Walnut Creek
Fremont
Half Moon Bay
South San Francisco
Redwood City
Vallejo
Sunnyvale
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to San Francisco for you.

Can I find flights from Greenville to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to San Francisco?

momondo helps you find the best flight between Greenville and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.


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1 adult
Tue 8/5
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