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Cheap flights from Greenville to San Francisco from $236

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to San Francisco departing on 12/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Greenville to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:44 pm - 12:21 am
GSP
-
SFO
9h 37m1 stop
United Airlines Logo
5:15 am - 5:03 pm
SFO
-
GSP
8h 48m1 stop
$324United Airlines
Wed, Dec 24 - Thu, Jan 1
Delta Logo
3:00 pm - 7:54 pm
GSP
-
SFO
7h 54m1 stop
Delta Logo
2:05 pm - 11:39 pm
SFO
-
GSP
6h 34m1 stop
$367Delta
Tue, Feb 17 - Tue, Feb 24
American Airlines Logo
8:43 am - 1:59 pm
GSP
-
SFO
8h 16m1 stop
American Airlines Logo
6:00 am - 6:34 pm
SFO
-
GSP
9h 34m2 stops
$372American Airlines
Tue, Feb 17 - Tue, Feb 24
Delta Logo
3:05 pm - 8:25 pm
GSP
-
SFO
8h 20m1 stop
Delta Logo
6:00 am - 4:56 pm
SFO
-
GSP
7h 56m1 stop
$377Delta
Wed, Jan 28 - Sat, Jan 31
American Airlines Logo
12:09 pm - 7:19 pm
GSP
-
SFO
10h 10m2 stops
American Airlines Logo
7:00 am - 7:07 pm
SFO
-
GSP
9h 07m1 stop
$382American Airlines
Wed, Jan 28 - Sat, Jan 31
American Airlines Logo
12:09 pm - 7:19 pm
GSP
-
SFO
10h 10m2 stops
American Airlines Logo
11:04 am - 11:51 pm
SFO
-
GSP
9h 47m2 stops
$387American Airlines
Wed, Jan 28 - Sat, Jan 31
American Airlines Logo
4:40 pm - 9:37 pm
GSP
-
SFO
7h 57m1 stop
American Airlines Logo
9:00 am - 8:48 pm
SFO
-
GSP
8h 48m1 stop
$396American Airlines
Tue, Jan 6 - Tue, Jan 13
American Airlines Logo
4:40 pm - 9:37 pm
GSP
-
SFO
7h 57m1 stop
American Airlines Logo
9:10 am - 8:56 pm
SFO
-
GSP
8h 46m2 stops
$401American Airlines
Tue, Jan 6 - Tue, Jan 13
United Airlines Logo
10:00 am - 5:19 pm
GSP
-
SFO
10h 19m1 stop
United Airlines Logo
11:56 pm - 10:16 am
SFO
-
GSP
7h 20m1 stop
$407United Airlines
Sun, Jan 25 - Tue, Jan 27
Southwest Logo
10:45 am - 3:45 pm
GSP
-
SFO
8h 00m1 stop
Southwest Logo
5:50 pm - 10:40 am
SFO
-
GSP
13h 50m2 stops
$412Southwest
Sun, Jan 25 - Tue, Jan 27

Delta flights from Greenville to San Francisco

Our best Delta deals on Greenville to San Francisco flight tickets
Delta
Feb 17
GSP3:00 pmGreenville
7h 54m
1 stop
SFO7:54 pmSan Francisco
Feb 24
SFO2:05 pmSan Francisco
6h 34m
1 stop
GSP11:39 pmGreenville
$367
Find similar
Delta
Jan 28
GSP3:05 pmGreenville
8h 20m
1 stop
SFO8:25 pmSan Francisco
Jan 31
SFO6:00 amSan Francisco
7h 56m
1 stop
GSP4:56 pmGreenville
$377
Find similar
Delta
May 12
GSP3:42 pmGreenville
10h 07m
1 stop
SFO10:49 pmSan Francisco
May 23
SFO11:45 pmSan Francisco
6h 43m
1 stop
GSP9:28 amGreenville
$447
Find similar

American Airlines flights from Greenville to San Francisco

Our best American Airlines deals on Greenville to San Francisco flight tickets
American Airlines
Feb 17
GSP8:43 amGreenville
8h 16m
1 stop
SFO1:59 pmSan Francisco
Feb 24
SFO6:00 amSan Francisco
9h 34m
2 stops
GSP6:34 pmGreenville
$372
Find similar
American Airlines
Jan 28
GSP12:09 pmGreenville
10h 10m
2 stops
SFO7:19 pmSan Francisco
Jan 31
SFO7:00 amSan Francisco
9h 07m
1 stop
GSP7:07 pmGreenville
$382
Find similar
American Airlines
Jan 28
GSP12:09 pmGreenville
10h 10m
2 stops
SFO7:19 pmSan Francisco
Jan 31
SFO11:04 amSan Francisco
9h 47m
2 stops
GSP11:51 pmGreenville
$387
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 12/24

5:44 pm-12:21 am

1 stop9h 37m

San Francisco

Thu 1/1

5:15 am-5:03 pm

1 stop8h 48m

$324

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Tue 2/17

3:00 pm-7:54 pm

1 stop7h 54m

San Francisco

Tue 2/24

2:05 pm-11:39 pm

1 stop6h 34m

$367

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Tue 2/17

8:43 am-1:59 pm

1 stop8h 16m

San Francisco

Tue 2/24

6:00 am-6:34 pm

2 stops9h 34m

$372

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 1/28

3:05 pm-8:25 pm

1 stop8h 20m

San Francisco

Sat 1/31

6:00 am-4:56 pm

1 stop7h 56m

$377

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 1/28

12:09 pm-7:19 pm

2 stops10h 10m

San Francisco

Sat 1/31

7:00 am-7:07 pm

1 stop9h 07m

$382

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 1/28

12:09 pm-7:19 pm

2 stops10h 10m

San Francisco

Sat 1/31

11:04 am-11:51 pm

2 stops9h 47m

$387

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Tue 1/6

4:40 pm-9:37 pm

1 stop7h 57m

San Francisco

Tue 1/13

9:00 am-8:48 pm

1 stop8h 48m

$396

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Tue 1/6

4:40 pm-9:37 pm

1 stop7h 57m

San Francisco

Tue 1/13

9:10 am-8:56 pm

2 stops8h 46m

$401

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sun 1/25

10:00 am-5:19 pm

1 stop10h 19m

San Francisco

Tue 1/27

11:56 pm-10:16 am

1 stop7h 20m

$407

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sun 1/25

10:45 am-3:45 pm

1 stop8h 00m

San Francisco

Tue 1/27

5:50 pm-10:40 am

2 stops13h 50m

$412

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Greenville to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of August, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $398.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Greenville to San Francisco is on a Wednesday when prices can be found for as low as $419. The most expensive day to fly to San Francisco is Thursday, with ticket prices averaging around $575.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Greenville to San Francisco flights are usually those with departure times at noon. Our users have found flights to San Francisco at noon for as low as $498. Flights in the afternoon are often more expensive with an average ticket price of $528.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $464 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Greenville for as low as $335 on momondo.

How have Greenville to San Francisco flight prices changed over time?

As of December 2025, prices for Greenville to San Francisco flights are approximately 77% more expensive when compared to flights at the same time last year.

When to book flights from Greenville to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to San Francisco (GSP to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Francisco

Fastest flight time

7h 33m

Direct flights

None
The fastest flight from Greenville to San Francisco takes 7h 33m
There are no direct flights from Greenville to San Francisco. There are no popular flight routes from Greenville to San Francisco.
Search flight deals

  • How far is Greenville to San Francisco by plane?

    San Francisco is 2218.5 mi away from Greenville. A reasonable flight in good conditions will take 7h 33m.

  • When did momondo last update prices for flights from Greenville Airport to San Francisco Airport?

    Prices for flights from Greenville Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to San Francisco Airport?

  • How old do you have to be to fly from Greenville Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents you'll need for your trip to San Francisco Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to San Francisco?

Best airlines flying from Greenville to San Francisco

Compare and see reviews for airlines that fly from Greenville to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $276Free CancellationRating
7.9
8,008 reviews
Search Delta flights
United AirlinesPriceFrom $311Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights
SouthwestPriceFrom $330Free CancellationRating
7.9
4,253 reviews
Search Southwest flights
American AirlinesPriceFrom $332Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Big Sur
Calistoga
Santa Clara
Walnut Creek
Berkeley
Daly City
Fremont
Half Moon Bay
Vallejo
Salinas
Livermore
Turlock
Sunnyvale

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to San Francisco for you.

Can I find flights from Greenville to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to San Francisco?

momondo helps you find the best flight between Greenville and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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