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Cheap flights from Greenville to San Francisco from $169

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Greenville to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:25 pm - 12:44 amGSP  Greenville-SFO San Francisco
10h 19m1 stop Dallas/Fort Worth
American Airlines Logo
10:03 pm - 9:15 amSFO  San Francisco-GSP Greenville
8h 12m1 stop Charlotte Douglas
$337American Airlines
Wed, Oct 21 - Sat, Oct 31
American Airlines Logo
7:45 pm - 12:44 amGSP  Greenville-SFO San Francisco
7h 59m1 stop Dallas/Fort Worth
American Airlines Logo
10:03 pm - 9:15 amSFO  San Francisco-GSP Greenville
8h 12m1 stop Charlotte Douglas
$337American Airlines
Wed, Oct 21 - Sat, Oct 31
Delta Logo
7:14 pm - 11:56 pmGSP  Greenville-SFO San Francisco
7h 42m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:25 pm - 10:01 amSFO  San Francisco-GSP Greenville
8h 36m1 stop Atlanta Hartsfield-Jackson
$337Delta
Thu, Oct 22 - Tue, Nov 3
Delta Logo
12:18 pm - 6:54 pmGSP  Greenville-SFO San Francisco
9h 36m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:40 pm - 10:12 amSFO  San Francisco-GSP Greenville
8h 32m1 stop Detroit Metropolitan Wayne County
$337Delta
Thu, Dec 3 - Mon, Dec 7
Southwest Logo
8:25 am - 2:35 pmGSP  Greenville-SFO San Francisco
9h 10m1 stop Baltimore/Washington
Southwest Logo
11:35 pm - 2:10 pmSFO  San Francisco-GSP Greenville
11h 35m2 stops Chicago Midway Nashville Intl
$342Southwest
Thu, Oct 22 - Tue, Nov 3
Southwest Logo
7:00 am - 12:45 pmGSP  Greenville-SFO San Francisco
8h 45m2 stops Nashville Intl San Diego
Southwest Logo
6:00 am - 4:25 pmSFO  San Francisco-GSP Greenville
7h 25m1 stop Nashville Intl
$342Southwest
Wed, Oct 21 - Sat, Oct 31
United Airlines Logo
6:30 am - 11:36 amGSP  Greenville-SFO San Francisco
8h 06m1 stop Chicago O'Hare Intl
United Airlines Logo
10:34 pm - 9:33 amSFO  San Francisco-GSP Greenville
7h 59m1 stop Chicago O'Hare Intl
$349United Airlines
Wed, Dec 16 - Tue, Dec 29
United Airlines Logo
7:37 pm - 1:30 amGSP  Greenville-SFO San Francisco
8h 53m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
11:30 pm - 9:33 amSFO  San Francisco-GSP Greenville
7h 03m1 stop Chicago O'Hare Intl
$421United Airlines
Tue, Dec 22 - Wed, Dec 30
Multiple Airlines Logo
7:10 pm - 12:01 pmGSP  Greenville-SFO San Francisco
19h 51m1 stop Cincinnati Cinci./N. Kentucky
Multiple Airlines Logo
10:05 pm - 7:44 pmSFO  San Francisco-GSP Greenville
18h 39m2 stops Atlanta Hartsfield-Jackson Tampa
$438Multiple Airlines
Mon, Sep 28 - Tue, Sep 29
Multiple Airlines Logo
7:20 pm - 12:01 pmGSP  Greenville-SFO San Francisco
19h 41m1 stop Cincinnati Cinci./N. Kentucky
Multiple Airlines Logo
10:05 pm - 7:44 pmSFO  San Francisco-GSP Greenville
18h 39m2 stops Atlanta Hartsfield-Jackson Tampa
$449Multiple Airlines
Mon, Oct 5 - Tue, Oct 6

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Southwest flights from Greenville to San Francisco

Our best Southwest deals on Greenville to San Francisco flight tickets
Southwest
Oct 21
GSP7:00 amGreenville
8h 45m
2 stops
SFO12:45 pmSan Francisco
Oct 31
SFO6:00 amSan Francisco
7h 25m
1 stop
GSP4:25 pmGreenville
$342
Southwest
Oct 22
GSP6:25 amGreenville
9h 40m
2 stops
SFO1:05 pmSan Francisco
Nov 3
SFO11:35 pmSan Francisco
11h 35m
2 stops
GSP2:10 pmGreenville
$347
Southwest
Jan 5
GSP11:20 amGreenville
7h 30m
1 stop
SFO3:50 pmSan Francisco
Jan 12
SFO11:10 amSan Francisco
6h 50m
1 stop
GSP9:00 pmGreenville
$364

United Airlines flights from Greenville to San Francisco

Our best United Airlines deals on Greenville to San Francisco flight tickets
United Airlines
Dec 16
GSP6:30 amGreenville
8h 06m
1 stop
SFO11:36 amSan Francisco
Dec 29
SFO10:34 pmSan Francisco
7h 59m
1 stop
GSP9:33 amGreenville
$349
United Airlines
Oct 14
GSP5:46 pmGreenville
9h 44m
1 stop
SFO12:30 amSan Francisco
Oct 17
SFO5:00 amSan Francisco
9h 05m
1 stop
GSP5:05 pmGreenville
$439
United Airlines
Sep 30
GSP4:25 pmGreenville
9h 26m
1 stop
SFO10:51 pmSan Francisco
Oct 3
SFO6:10 amSan Francisco
7h 55m
1 stop
GSP5:05 pmGreenville
$447

momondo Fare Finder

 
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Wed 10/21

5:25 pm-12:44 am

1 stop10h 19m

San Francisco

Sat 10/31

10:03 pm-9:15 am

1 stop8h 12m

$337

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Wed 10/21

7:45 pm-12:44 am

1 stop7h 59m

San Francisco

Sat 10/31

10:03 pm-9:15 am

1 stop8h 12m

$337

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Thu 10/22

7:14 pm-11:56 pm

1 stop7h 42m

San Francisco

Tue 11/3

10:25 pm-10:01 am

1 stop8h 36m

$337

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Thu 12/3

12:18 pm-6:54 pm

1 stop9h 36m

San Francisco

Mon 12/7

10:40 pm-10:12 am

1 stop8h 32m

$337

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Thu 10/22

8:25 am-2:35 pm

1 stop9h 10m

San Francisco

Tue 11/3

11:35 pm-2:10 pm

2 stops11h 35m

$342

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Wed 10/21

7:00 am-12:45 pm

2 stops8h 45m

San Francisco

Sat 10/31

6:00 am-4:25 pm

1 stop7h 25m

$342

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Wed 12/16

6:30 am-11:36 am

1 stop8h 06m

San Francisco

Tue 12/29

10:34 pm-9:33 am

1 stop7h 59m

$349
Quickest round-trip

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Tue 12/22

7:37 pm-1:30 am

1 stop8h 53m

San Francisco

Wed 12/30

11:30 pm-9:33 am

1 stop7h 03m

$421

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Mon 9/28

7:10 pm-12:01 pm

1 stop19h 51m

San Francisco

Tue 9/29

10:05 pm-7:44 pm

2 stops18h 39m

$438

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Mon 10/5

7:20 pm-12:01 pm

1 stop19h 41m

San Francisco

Tue 10/6

10:05 pm-7:44 pm

2 stops18h 39m

$449

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Greenville to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and San Francisco?

Prices are currently low for flights on this route.

Typical prices usually range from $340 to $697.
The lowest price recently found on this route was $337.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in July is also cheap. Prices for this month can be found on momondo for an average of $478.

How far in advance should I book a flight from Greenville to San Francisco?

You are more likely to see cheaper flights to San Francisco from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $546 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Greenville for as low as $424 on momondo.

How have Greenville to San Francisco flight prices changed over time?

As of September 2026, prices for Greenville to San Francisco flights are approximately 1% cheaper when compared to flights at the same time last year.

When to book flights from Greenville to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to San Francisco (GSP to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Francisco

Best Price Found

$169

Fastest flight time

7h 54m

Direct flights

None
The best one-way flight to San Francisco from Greenville in the past 72 hours is $169. The best round-trip flight deal from Greenville to San Francisco found on momondo in the last 72 hours is $337.
The fastest flight from Greenville to San Francisco takes 7h 54m
There are no direct flights from Greenville to San Francisco. There are no popular flight routes from Greenville to San Francisco.
Search flight deals

Frequently asked questions about flying from Greenville to San Francisco

  • How far is Greenville to San Francisco by plane?

    San Francisco is 2218.0 mi away from Greenville. A reasonable flight in good conditions will take 7h 54m.

  • When did momondo last update prices for flights from Greenville Airport to San Francisco Airport?

    Prices for flights from Greenville Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to San Francisco Airport?

  • How old do you have to be to fly from Greenville Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents you'll need for your trip to San Francisco Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to San Francisco?

Best airlines flying from Greenville to San Francisco

Compare and see reviews for airlines that fly from Greenville to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $311Free CancellationRating
7.4
10,189 reviews
Search United Airlines flights
American AirlinesPriceFrom $333Free CancellationRating
7.1
12,045 reviews
Search American Airlines flights
DeltaPriceFrom $362Free CancellationRating
7.8
8,554 reviews
Search Delta flights
SouthwestPriceFrom $402Free CancellationRating
8.0
4,195 reviews
Search Southwest flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Bodega Bay
Hayward
Fremont
Berkeley
Walnut Creek
Santa Clara
Sunnyvale
Vallejo
Salinas
Roseville
Half Moon Bay
Sonoma
Daly City
Milpitas
Marina
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to San Francisco for you.

Can I find flights from Greenville to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to San Francisco?

momondo helps you find the best flight between Greenville and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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