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Cheap flights from Greenville to San Francisco from $156

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to San Francisco departing on 8/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Greenville to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:37 pm - 7:18 pm
GSP
-
SFO
8h 41m
1 stop
American Airlines Logo
6:36 am - 4:34 pm
SFO
-
GSP
6h 58m
1 stop
$311American Airlines
Sat, Aug 29 - Thu, Sep 10
Delta Logo
6:25 pm - 11:57 pm
GSP
-
SFO
8h 32m
1 stop
Delta Logo
10:59 pm - 10:24 am
SFO
-
GSP
8h 25m
1 stop
$316Delta
Fri, Sep 11 - Sat, Oct 3
Southwest Logo
6:45 am - 2:45 pm
GSP
-
SFO
11h 00m
2 stops
Southwest Logo
11:40 pm - 12:25 pm
SFO
-
GSP
9h 45m
2 stops
$321Southwest
Sat, Aug 15 - Mon, Aug 24
Southwest Logo
7:00 am - 1:10 pm
GSP
-
SFO
9h 10m
2 stops
Southwest Logo
11:05 pm - 12:30 pm
SFO
-
GSP
10h 25m
1 stop
$322Southwest
Mon, Aug 31 - Wed, Sep 9
American Airlines Logo
7:46 pm - 12:44 am
GSP
-
SFO
7h 58m
1 stop
American Airlines Logo
10:51 am - 9:32 pm
SFO
-
GSP
7h 41m
1 stop
$329American Airlines
Mon, Oct 5 - Sat, Oct 10
American Airlines Logo
8:05 pm - 12:11 am
GSP
-
SFO
7h 06m
1 stop
American Airlines Logo
11:29 pm - 10:39 am
SFO
-
GSP
8h 10m
1 stop
$330American Airlines
Thu, Sep 3 - Sat, Sep 5
American Airlines Logo
5:24 pm - 10:30 pm
GSP
-
SFO
8h 06m
1 stop
American Airlines Logo
6:36 am - 4:34 pm
SFO
-
GSP
6h 58m
1 stop
$337American Airlines
Thu, Sep 24 - Tue, Sep 29
Southwest Logo
7:00 am - 2:40 pm
GSP
-
SFO
10h 40m
2 stops
Southwest Logo
11:40 pm - 12:30 pm
SFO
-
GSP
9h 50m
2 stops
$339Southwest
Mon, Aug 31 - Wed, Sep 9
Southwest Logo
7:00 am - 1:50 pm
GSP
-
SFO
9h 50m
2 stops
Southwest Logo
6:50 am - 9:00 pm
SFO
-
GSP
11h 10m
2 stops
$344Southwest
Wed, Sep 16 - Wed, Sep 23
Southwest Logo
7:00 am - 1:50 pm
GSP
-
SFO
9h 50m
2 stops
Southwest Logo
6:50 am - 9:00 pm
SFO
-
GSP
11h 10m
2 stops
$365Southwest
Wed, Sep 9 - Wed, Sep 23

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Southwest flights from Greenville to San Francisco

Our best Southwest deals on Greenville to San Francisco flight tickets
Southwest
Aug 15
GSP6:45 amGreenville
11h 00m
2 stops
SFO2:45 pmSan Francisco
Aug 24
SFO11:40 pmSan Francisco
9h 45m
2 stops
GSP12:25 pmGreenville
$321
Southwest
Aug 31
GSP7:00 amGreenville
9h 10m
2 stops
SFO1:10 pmSan Francisco
Sep 9
SFO11:05 pmSan Francisco
10h 25m
1 stop
GSP12:30 pmGreenville
$322
Southwest
Aug 31
GSP7:00 amGreenville
10h 40m
2 stops
SFO2:40 pmSan Francisco
Sep 9
SFO11:40 pmSan Francisco
9h 50m
2 stops
GSP12:30 pmGreenville
$339

Delta flights from Greenville to San Francisco

Our best Delta deals on Greenville to San Francisco flight tickets
Delta
Sep 11
GSP6:25 pmGreenville
8h 32m
1 stop
SFO11:57 pmSan Francisco
Oct 3
SFO10:59 pmSan Francisco
8h 25m
1 stop
GSP10:24 amGreenville
$316
Delta
Sep 6
GSP5:20 pmGreenville
9h 38m
1 stop
SFO11:58 pmSan Francisco
Sep 21
SFO4:59 pmSan Francisco
14h 25m
2 stops
GSP10:24 amGreenville
$386
Delta
Sep 6
GSP5:20 pmGreenville
9h 38m
1 stop
SFO11:58 pmSan Francisco
Sep 21
SFO10:59 pmSan Francisco
8h 25m
1 stop
GSP10:24 amGreenville
$409

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 26, 2026.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 8/29

1:37 pm-7:18 pm

1 stop8h 41m

San Francisco

Thu 9/10

6:36 am-4:34 pm

1 stop6h 58m

$311

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Fri 9/11

6:25 pm-11:57 pm

1 stop8h 32m

San Francisco

Sat 10/3

10:59 pm-10:24 am

1 stop8h 25m

$316

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 8/15

6:45 am-2:45 pm

2 stops11h 00m

San Francisco

Mon 8/24

11:40 pm-12:25 pm

2 stops9h 45m

$321

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Mon 8/31

7:00 am-1:10 pm

2 stops9h 10m

San Francisco

Wed 9/9

11:05 pm-12:30 pm

1 stop10h 25m

$322

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Mon 10/5

7:46 pm-12:44 am

1 stop7h 58m

San Francisco

Sat 10/10

10:51 am-9:32 pm

1 stop7h 41m

$329

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Thu 9/3

8:05 pm-12:11 am

1 stop7h 06m

San Francisco

Sat 9/5

11:29 pm-10:39 am

1 stop8h 10m

$330
Quickest round-trip

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Thu 9/24

5:24 pm-10:30 pm

1 stop8h 06m

San Francisco

Tue 9/29

6:36 am-4:34 pm

1 stop6h 58m

$337

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Mon 8/31

7:00 am-2:40 pm

2 stops10h 40m

San Francisco

Wed 9/9

11:40 pm-12:30 pm

2 stops9h 50m

$339

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 9/16

7:00 am-1:50 pm

2 stops9h 50m

San Francisco

Wed 9/23

6:50 am-9:00 pm

2 stops11h 10m

$344

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 9/9

7:00 am-1:50 pm

2 stops9h 50m

San Francisco

Wed 9/23

6:50 am-9:00 pm

2 stops11h 10m

$365

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Greenville to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and San Francisco?

Prices are currently low for flights on this route.

Typical prices usually range from $382 to $548.
The lowest price recently found on this route was $311.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $412.

How far in advance should I book a flight from Greenville to San Francisco?

You are more likely to see cheaper flights to San Francisco from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $522 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Greenville for as low as $312 on momondo.

How have Greenville to San Francisco flight prices changed over time?

As of July 2026, prices for Greenville to San Francisco flights are approximately 31% cheaper when compared to flights at the same time last year.

When to book flights from Greenville to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to San Francisco (GSP to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Francisco

Fastest flight time

7h 59m

Direct flights

None
The fastest flight from Greenville to San Francisco takes 7h 59m
There are no direct flights from Greenville to San Francisco. There are no popular flight routes from Greenville to San Francisco.
Search flight deals

Frequently asked questions about flying from Greenville to San Francisco

  • How far is Greenville to San Francisco by plane?

    San Francisco is 2218.0 mi away from Greenville. A reasonable flight in good conditions will take 7h 59m.

  • When did momondo last update prices for flights from Greenville Airport to San Francisco Airport?

    Prices for flights from Greenville Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to San Francisco Airport?

  • How old do you have to be to fly from Greenville Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents you'll need for your trip to San Francisco Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to San Francisco?

Best airlines flying from Greenville to San Francisco

Compare and see reviews for airlines that fly from Greenville to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $276Free CancellationRating
7.8
8,487 reviews
Search Delta flights
United AirlinesPriceFrom $311Free CancellationRating
7.4
10,040 reviews
Search United Airlines flights
American AirlinesPriceFrom $312Free CancellationRating
7.1
11,844 reviews
Search American Airlines flights
SouthwestPriceFrom $330Free CancellationRating
8.0
4,231 reviews
Search Southwest flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Fremont
Hayward
Walnut Creek
Bodega Bay
Sonoma
Roseville
Santa Clara
Berkeley
Vallejo
Salinas
Sunnyvale
Burlingame
Daly City
Milpitas
Palo Alto
Big Sur

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to San Francisco for you.

Can I find flights from Greenville to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to San Francisco?

momondo helps you find the best flight between Greenville and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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