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Cheap flights from Greenville to San Francisco from $148

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Greenville to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
8:15 am - 1:45 pmGSP  Greenville-SFO San Francisco
8h 30m1 stop Baltimore/Washington
Southwest Logo
9:25 pm - 10:45 amSFO  San Francisco-GSP Greenville
10h 20m1 stop Baltimore/Washington
$303Southwest
Fri, Dec 11 - Mon, Dec 14
Southwest Logo
8:05 am - 1:50 pmGSP  Greenville-SFO San Francisco
8h 45m1 stop Baltimore/Washington
Southwest Logo
9:25 pm - 10:45 amSFO  San Francisco-GSP Greenville
10h 20m1 stop Baltimore/Washington
$303Southwest
Fri, Dec 4 - Mon, Dec 14
American Airlines Logo
2:31 pm - 8:57 pmGSP  Greenville-SFO San Francisco
9h 26m1 stop Charlotte Douglas
American Airlines Logo
6:38 am - 4:23 pmSFO  San Francisco-GSP Greenville
6h 45m1 stop Dallas/Fort Worth
$317American Airlines
Thu, Dec 3 - Mon, Dec 7
American Airlines Logo
5:17 pm - 11:29 pmGSP  Greenville-SFO San Francisco
9h 12m1 stop Dallas/Fort Worth
American Airlines Logo
8:30 am - 7:00 pmSFO  San Francisco-GSP Greenville
7h 30m1 stop Charlotte Douglas
$317American Airlines
Thu, Dec 3 - Mon, Dec 7
Delta Logo
7:20 am - 2:26 pmGSP  Greenville-SFO San Francisco
10h 06m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:00 am - 6:19 pmSFO  San Francisco-GSP Greenville
9h 19m1 stop Atlanta Hartsfield-Jackson
$317Delta
Thu, Nov 26 - Sat, Dec 5
Delta Logo
7:00 am - 2:33 pmGSP  Greenville-SFO San Francisco
10h 33m1 stop Detroit Metropolitan Wayne County
Delta Logo
9:59 pm - 9:40 amSFO  San Francisco-GSP Greenville
8h 41m1 stop Atlanta Hartsfield-Jackson
$317Delta
Wed, Dec 9 - Mon, Dec 14
United Airlines Logo
7:43 pm - 1:29 amGSP  Greenville-SFO San Francisco
8h 46m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
5:00 am - 3:03 pmSFO  San Francisco-GSP Greenville
7h 03m1 stop Denver Intl
$317United Airlines
Thu, Nov 19 - Thu, Nov 26
United Airlines Logo
6:20 am - 11:50 amGSP  Greenville-SFO San Francisco
8h 30m1 stop Chicago O'Hare Intl
United Airlines Logo
11:30 pm - 9:30 amSFO  San Francisco-GSP Greenville
7h 00m1 stop Chicago O'Hare Intl
$317United Airlines
Tue, Nov 10 - Sat, Nov 14
Alaska Airlines Logo
11:36 am - 11:29 pmGSP  Greenville-SFO San Francisco
14h 53m2 stops Chicago O'Hare Intl Portland
Alaska Airlines Logo
7:05 pm - 11:06 amSFO  San Francisco-GSP Greenville
13h 01m2 stops Seattle/Tacoma Intl Chicago O'Hare Intl
$679Alaska Airlines
Thu, Dec 3 - Mon, Dec 7
Alaska Airlines Logo
11:36 am - 11:29 pmGSP  Greenville-SFO San Francisco
14h 53m2 stops Chicago O'Hare Intl Portland
Alaska Airlines Logo
7:40 am - 9:52 pmSFO  San Francisco-GSP Greenville
11h 12m2 stops Portland Dallas/Fort Worth
$679Alaska Airlines
Thu, Dec 10 - Sun, Dec 13

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Alaska Airlines flights from Greenville to San Francisco

Our best Alaska Airlines deals on Greenville to San Francisco flight tickets
Alaska Airlines
Nov 5
GSP11:40 amGreenville
13h 03m
2 stops
SFO9:43 pmSan Francisco
Nov 6
SFO5:00 pmSan Francisco
22h 06m
2 stops
GSP6:06 pmGreenville
$856
Alaska Airlines
Oct 27
GSP11:38 amGreenville
24h 59m
2 stops
SFO9:37 amSan Francisco
Nov 2
SFO5:42 pmSan Francisco
14h 25m
2 stops
GSP11:07 amGreenville
$907
Alaska Airlines
Oct 30
GSP6:01 amGreenville
13h 07m
2 stops
SFO4:08 pmSan Francisco
Nov 3
SFO5:42 pmSan Francisco
14h 25m
2 stops
GSP11:07 amGreenville
$986

Delta flights from Greenville to San Francisco

Our best Delta deals on Greenville to San Francisco flight tickets
Delta
Dec 3
GSP10:57 amGreenville
10h 17m
1 stop
SFO6:14 pmSan Francisco
Dec 7
SFO11:59 pmSan Francisco
8h 14m
1 stop
GSP11:13 amGreenville
$317
Delta
Nov 26
GSP8:15 amGreenville
7h 24m
1 stop
SFO12:39 pmSan Francisco
Dec 8
SFO2:59 pmSan Francisco
15h 41m
2 stops
GSP9:40 amGreenville
$336
Delta
Nov 25
GSP10:32 amGreenville
9h 44m
1 stop
SFO5:16 pmSan Francisco
Dec 7
SFO10:59 pmSan Francisco
7h 41m
1 stop
GSP9:40 amGreenville
$362

momondo Fare Finder

 
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Fri 12/11

8:15 am-1:45 pm

1 stop8h 30m

San Francisco

Mon 12/14

9:25 pm-10:45 am

1 stop10h 20m

$303

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Fri 12/4

8:05 am-1:50 pm

1 stop8h 45m

San Francisco

Mon 12/14

9:25 pm-10:45 am

1 stop10h 20m

$303

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Thu 12/3

2:31 pm-8:57 pm

1 stop9h 26m

San Francisco

Mon 12/7

6:38 am-4:23 pm

1 stop6h 45m

$317

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Thu 12/3

5:17 pm-11:29 pm

1 stop9h 12m

San Francisco

Mon 12/7

8:30 am-7:00 pm

1 stop7h 30m

$317

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Thu 11/26

7:20 am-2:26 pm

1 stop10h 06m

San Francisco

Sat 12/5

6:00 am-6:19 pm

1 stop9h 19m

$317

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Wed 12/9

7:00 am-2:33 pm

1 stop10h 33m

San Francisco

Mon 12/14

9:59 pm-9:40 am

1 stop8h 41m

$317

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Thu 11/19

7:43 pm-1:29 am

1 stop8h 46m

San Francisco

Thu 11/26

5:00 am-3:03 pm

1 stop7h 03m

$317
Quickest round-trip

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Tue 11/10

6:20 am-11:50 am

1 stop8h 30m

San Francisco

Sat 11/14

11:30 pm-9:30 am

1 stop7h 00m

$317

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Thu 12/3

11:36 am-11:29 pm

2 stops14h 53m

San Francisco

Mon 12/7

7:05 pm-11:06 am

2 stops13h 01m

$679

GreenvilleSan Francisco

GSP Greenville - SFO San Francisco

GSPSFO

Greenville

Thu 12/10

11:36 am-11:29 pm

2 stops14h 53m

San Francisco

Sun 12/13

7:40 am-9:52 pm

2 stops11h 12m

$679

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Greenville to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Greenville and San Francisco?

Prices are currently low for flights on this route.

Typical prices usually range from $414 to $620.
The lowest price recently found on this route was $303.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in December is also cheap. Prices for this month can be found on momondo for an average of $477.

How far in advance should I book a flight from Greenville to San Francisco?

You are more likely to see cheaper flights to San Francisco from Greenville when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $547 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Greenville for as low as $424 on momondo.

How have Greenville to San Francisco flight prices changed over time?

As of October 2026, prices for Greenville to San Francisco flights are approximately 6% cheaper when compared to flights at the same time last year.

When to book flights from Greenville to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Greenville to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Greenville to San Francisco (GSP to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to San Francisco

Best Price Found

$148

Fastest flight time

7h 30m

Direct flights

None
The best one-way flight to San Francisco from Greenville in the past 72 hours is $148. The best round-trip flight deal from Greenville to San Francisco found on momondo in the last 72 hours is $303.
The fastest flight from Greenville to San Francisco takes 7h 30m
There are no direct flights from Greenville to San Francisco. There are no popular flight routes from Greenville to San Francisco.
Search flight deals

Frequently asked questions about flying from Greenville to San Francisco

  • How far is Greenville to San Francisco by plane?

    San Francisco is 2218.0 mi away from Greenville. A reasonable flight in good conditions will take 7h 30m.

  • When did momondo last update prices for flights from Greenville Airport to San Francisco Airport?

    Prices for flights from Greenville Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to San Francisco Airport?

  • How old do you have to be to fly from Greenville Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents you'll need for your trip to San Francisco Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Greenville to San Francisco?

Best airlines flying from Greenville to San Francisco

Compare and see reviews for airlines that fly from Greenville to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $318Free CancellationRating
7.8
8,668 reviews
Search Delta flights
United AirlinesPriceFrom $334Free CancellationRating
7.3
10,421 reviews
Search United Airlines flights
American AirlinesPriceFrom $336Free CancellationRating
7.0
12,190 reviews
Search American Airlines flights
SouthwestPriceFrom $402Free CancellationRating
7.9
4,214 reviews
Search Southwest flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Hayward
Bodega Bay
Walnut Creek
Santa Clara
Fremont
Berkeley
Sunnyvale
Half Moon Bay
Vallejo
Roseville
Salinas
Sonoma
Milpitas
Daly City
Palo Alto
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to San Francisco for you.

Can I find flights from Greenville to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Greenville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Greenville to San Francisco?

momondo helps you find the best flight between Greenville and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Greenville to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Greenville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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