Cheap flights from Detroit Metropolitan Wayne County Airport to Los Angeles from $54

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Los Angeles departing on 3/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:00 am - 10:01 am
DTW
-
SNA
31h 01m
1 stop
Frontier Logo
5:54 pm - 12:29 am
SNA
-
DTW
27h 35m
1 stop
$156Frontier
Wed, Mar 18 - Mon, Mar 23
Spirit Airlines Logo
9:01 am - 12:25 pm
DTW
-
SNA
6h 24m
1 stop
Spirit Airlines Logo
1:20 pm - 4:40 am
SNA
-
DTW
12h 20m
1 stop
$161Spirit Airlines
Mon, Mar 9 - Tue, Mar 10
Spirit Airlines Logo
9:01 am - 12:25 pm
DTW
-
SNA
6h 24m
1 stop
Spirit Airlines Logo
6:45 am - 6:20 pm
SNA
-
DTW
8h 35m
1 stop
$171Spirit Airlines
Tue, Feb 24 - Sat, Feb 28
Spirit Airlines Logo
9:01 am - 8:57 pm
DTW
-
SNA
14h 56m
1 stop
Spirit Airlines Logo
4:37 pm - 11:45 am
SNA
-
DTW
16h 08m
2 stops
$172Spirit Airlines
Mon, Mar 9 - Tue, Mar 10
Spirit Airlines Logo
9:01 am - 3:42 pm
DTW
-
SNA
9h 41m
1 stop
Spirit Airlines Logo
6:45 am - 6:20 pm
SNA
-
DTW
8h 35m
1 stop
$182Spirit Airlines
Tue, Feb 24 - Sat, Feb 28
Frontier Logo
10:27 pm - 10:47 am
DTW
-
SNA
15h 20m
1 stop
Frontier Logo
1:12 pm - 10:59 am
SNA
-
DTW
18h 47m
2 stops
$186Frontier
Fri, Mar 6 - Mon, Mar 9
Spirit Airlines Logo
9:01 am - 12:25 pm
DTW
-
SNA
6h 24m
1 stop
Spirit Airlines Logo
6:45 am - 11:57 pm
SNA
-
DTW
14h 12m
2 stops
$189Spirit Airlines
Tue, Feb 24 - Sat, Feb 28
Multiple Airlines Logo
6:00 am - 1:44 pm
DTW
-
SNA
10h 44m
1 stop
Multiple Airlines Logo
7:45 am - 8:53 pm
SNA
-
DTW
10h 08m
1 stop
$192Multiple Airlines
Sat, May 2 - Tue, May 5
Spirit Airlines Logo
9:01 am - 12:25 pm
DTW
-
SNA
6h 24m
1 stop
Spirit Airlines Logo
4:37 pm - 11:45 am
SNA
-
DTW
16h 08m
2 stops
$193Spirit Airlines
Wed, Mar 4 - Wed, Mar 4
Multiple Airlines Logo
6:00 am - 10:01 am
DTW
-
SNA
31h 01m
1 stop
Multiple Airlines Logo
2:53 pm - 10:59 am
SNA
-
DTW
17h 06m
2 stops
$195Multiple Airlines
Wed, Mar 18 - Mon, Mar 23

Frontier flights from Detroit Metropolitan Wayne County Airport to Santa Ana, California

Our best Frontier deals on Detroit Metropolitan Wayne County Airport to Santa Ana, California flight tickets
Frontier
Mar 18
DTW6:00 amDetroit Metropolitan Wayne County
31h 01m
1 stop
SNA10:01 amSanta Ana J. Wayne/Orange Cnty
Mar 23
SNA5:54 pmSanta Ana J. Wayne/Orange Cnty
27h 35m
1 stop
DTW12:29 amDetroit Metropolitan Wayne County
$156
Frontier
Mar 6
DTW10:27 pmDetroit Metropolitan Wayne County
15h 20m
1 stop
SNA10:47 amSanta Ana J. Wayne/Orange Cnty
Mar 9
SNA1:12 pmSanta Ana J. Wayne/Orange Cnty
18h 47m
2 stops
DTW10:59 amDetroit Metropolitan Wayne County
$186
Frontier
Mar 2
DTW6:00 amDetroit Metropolitan Wayne County
7h 46m
1 stop
SNA10:46 amSanta Ana J. Wayne/Orange Cnty
Mar 25
SNA9:50 amSanta Ana J. Wayne/Orange Cnty
11h 39m
1 stop
DTW12:29 amDetroit Metropolitan Wayne County
$211

Spirit Airlines flights from Detroit Metropolitan Wayne County Airport to Santa Ana, California

Our best Spirit Airlines deals on Detroit Metropolitan Wayne County Airport to Santa Ana, California flight tickets
Spirit Airlines
Mar 9
DTW9:01 amDetroit Metropolitan Wayne County
6h 24m
1 stop
SNA12:25 pmSanta Ana J. Wayne/Orange Cnty
Mar 10
SNA1:20 pmSanta Ana J. Wayne/Orange Cnty
12h 20m
1 stop
DTW4:40 amDetroit Metropolitan Wayne County
$161
Spirit Airlines
Feb 24
DTW9:01 amDetroit Metropolitan Wayne County
6h 24m
1 stop
SNA12:25 pmSanta Ana J. Wayne/Orange Cnty
Feb 28
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
8h 35m
1 stop
DTW6:20 pmDetroit Metropolitan Wayne County
$171
Spirit Airlines
Mar 9
DTW9:01 amDetroit Metropolitan Wayne County
14h 56m
1 stop
SNA8:57 pmSanta Ana J. Wayne/Orange Cnty
Mar 10
SNA4:37 pmSanta Ana J. Wayne/Orange Cnty
16h 08m
2 stops
DTW11:45 amDetroit Metropolitan Wayne County
$172

momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSanta Ana

DTW - SNA

DTWSNA

Detroit Metropolitan Wayne County

Wed 3/18

6:00 am-10:01 am

1 stop31h 01m

Santa Ana J. Wayne/Orange Cnty

Mon 3/23

5:54 pm-12:29 am

1 stop27h 35m

$156

DetroitSanta Ana

DTW - SNA

DTWSNA

Detroit Metropolitan Wayne County

Mon 3/9

9:01 am-12:25 pm

1 stop6h 24m

Santa Ana J. Wayne/Orange Cnty

Tue 3/10

1:20 pm-4:40 am

1 stop12h 20m

$161

DetroitSanta Ana

DTW - SNA

DTWSNA

Detroit Metropolitan Wayne County

Tue 2/24

9:01 am-12:25 pm

1 stop6h 24m

Santa Ana J. Wayne/Orange Cnty

Sat 2/28

6:45 am-6:20 pm

1 stop8h 35m

$171

DetroitSanta Ana

DTW - SNA

DTWSNA

Detroit Metropolitan Wayne County

Mon 3/9

9:01 am-8:57 pm

1 stop14h 56m

Santa Ana J. Wayne/Orange Cnty

Tue 3/10

4:37 pm-11:45 am

2 stops16h 08m

$172

DetroitSanta Ana

DTW - SNA

DTWSNA

Detroit Metropolitan Wayne County

Tue 2/24

9:01 am-3:42 pm

1 stop9h 41m

Santa Ana J. Wayne/Orange Cnty

Sat 2/28

6:45 am-6:20 pm

1 stop8h 35m

$182

DetroitSanta Ana

DTW - SNA

DTWSNA

Detroit Metropolitan Wayne County

Fri 3/6

10:27 pm-10:47 am

1 stop15h 20m

Santa Ana J. Wayne/Orange Cnty

Mon 3/9

1:12 pm-10:59 am

2 stops18h 47m

$186

DetroitSanta Ana

DTW - SNA

DTWSNA

Detroit Metropolitan Wayne County

Tue 2/24

9:01 am-12:25 pm

1 stop6h 24m

Santa Ana J. Wayne/Orange Cnty

Sat 2/28

6:45 am-11:57 pm

2 stops14h 12m

$189

DetroitSanta Ana

DTW - SNA

DTWSNA

Detroit Metropolitan Wayne County

Sat 5/2

6:00 am-1:44 pm

1 stop10h 44m

Santa Ana J. Wayne/Orange Cnty

Tue 5/5

7:45 am-8:53 pm

1 stop10h 08m

$192

DetroitSanta Ana

DTW - SNA

DTWSNA

Detroit Metropolitan Wayne County

Wed 3/4

9:01 am-12:25 pm

1 stop6h 24m

Santa Ana J. Wayne/Orange Cnty

Wed 3/4

4:37 pm-11:45 am

2 stops16h 08m

$193

DetroitSanta Ana

DTW - SNA

DTWSNA

Detroit Metropolitan Wayne County

Wed 3/18

6:00 am-10:01 am

1 stop31h 01m

Santa Ana J. Wayne/Orange Cnty

Mon 3/23

2:53 pm-10:59 am

2 stops17h 06m

$195

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, August is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $253. If you aren’t able to travel during the month of August, then book flights to Santa Ana, California from Detroit Metropolitan Wayne County Airport during July instead. Flights to Santa Ana, California in July, while not as cheap as those in August, still average around $348.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Detroit Metropolitan Wayne County Airport to Santa Ana, California is on a Saturday. Travelers who choose to depart for Santa Ana, California on a Saturday will often find tickets for as low as $389. The most expensive day to fly to Santa Ana, California is Monday, with ticket prices averaging around $689.

What is the cheapest Detroit Metropolitan Wayne County to Santa Ana J. Wayne/Orange Cnty flight route?

Fly from Detroit Metropolitan Wayne County to Santa Ana J. Wayne/Orange Cnty for the best Detroit Metropolitan Wayne County - Santa Ana J. Wayne/Orange Cnty flight prices

How far in advance should I book a flight to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $487 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from Detroit Metropolitan Wayne County Airport for as low as $158 on momondo.

What cabin class options are available on Detroit Metropolitan Wayne County to Santa Ana J. Wayne/Orange Cnty flights?

There are 4 cabin classes available to choose from on Detroit Metropolitan Wayne County to Santa Ana J. Wayne/Orange Cnty flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Detroit Metropolitan Wayne County Airport to Santa Ana, California flights?

No. A direct flight is the cheapest option for a flight between Detroit Metropolitan Wayne County Airport to Santa Ana, California.

How have Detroit Metropolitan Wayne County Airport to Santa Ana, California flight prices changed over time?

As of February 2026, prices for Detroit Metropolitan Wayne County Airport to Santa Ana, California flights are approximately 62% more expensive when compared to flights at the same time last year.

When to book flights from Detroit Metropolitan Wayne County Airport to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Santa Ana, California (DTW to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Santa Ana, California

Best Price Found

$398

Fastest flight time

4h 53m

Direct flights

Mon, Tue, Wed, Thu, Fri and Sat

Airports in Santa Ana, California

1 airport
The best one-way flight to Santa Ana, California from Detroit Metropolitan Wayne County Airport in the past 72 hours is $398. The best round-trip flight deal from Detroit Metropolitan Wayne County Airport to Santa Ana, California found on momondo in the last 72 hours is $599.
The fastest flight from Detroit Metropolitan Wayne County Airport to Santa Ana, California takes 4h 53m
Direct flights go from Detroit Metropolitan Wayne County Airport to Santa Ana, California on Monday, Tuesday, Wednesday, Thursday, Friday and Saturday. The only airline offering direct flights is Delta.
There is 1 airport in Santa Ana, California. From Detroit Metropolitan Wayne County Airport there are direct flights to Santa Ana J. Wayne/Orange Cnty (SNA).
  • How far is Detroit Metropolitan Wayne County to Santa Ana J. Wayne/Orange Cnty by plane?

    There are 1952.3 mi between Detroit Metropolitan Wayne County and Santa Ana J. Wayne/Orange Cnty. A reasonable flight in good conditions will take 4h 53m.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Detroit Metropolitan Wayne County Airport to Santa Ana, California?

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Santa Ana, California?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Santa Ana, California

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $104Free CancellationRating
6.3
8,411 reviews
Search Spirit Airlines flights
FrontierPriceFrom $139Free CancellationRating
5.7
3,052 reviews
Search Frontier flights
American AirlinesPriceFrom $216Free CancellationRating
7.2
11,222 reviews
Search American Airlines flights
SouthwestPriceFrom $384Free CancellationRating
8.0
4,274 reviews
Search Southwest flights
DeltaPriceFrom $399Free CancellationRating
7.9
8,144 reviews
Search Delta flights
  • Delta Flights From Detroit Metropolitan Wayne County Airport to Santa Ana, California

    The lowest priced Delta flight from Detroit Metropolitan Wayne County Airport to Santa Ana, California from the last 72 hours was $399. Generally, Delta has 5 flights on this route every week with an average price of $638. Delta is rated 7.9/10 by our users.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
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Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Santa Ana?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santa Ana from Detroit.

Can I find flights from Detroit to Santa Ana with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santa Ana from Detroit which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Detroit to Santa Ana?

Once all potential Detroit to Santa Ana flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Detroit to Santa Ana right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santa Ana from Detroit. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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Fri 3/6
Fri 3/13

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