Cheap flights from Detroit Metropolitan Wayne County Airport to San Diego from $127

If you are unable to visit San Diego during the month of August, then departing from Detroit Metropolitan Wayne County Airport during the month January is also very affordable. Most momondo users find prices during this month for around $334.

The cheapest day to depart from Detroit Metropolitan Wayne County Airport to San Diego is on a Saturday. Travelers who choose to depart for San Diego on a Saturday will often find tickets for as low as $519. If your travel schedule is flexible, try to avoid departing on a Wednesday because tickets tend to average around $589. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $551. Flights in the evening are often more expensive with an average ticket price of $578.

Fly from Detroit Metropolitan Wayne County to San Diego for the best Detroit Metropolitan Wayne County - San Diego flight prices

You are more likely to see cheaper flights to San Diego from Detroit Metropolitan Wayne County Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $455 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Detroit Metropolitan Wayne County Airport for as low as $377 on momondo.

There are 4 cabin classes available to choose from on Detroit Metropolitan Wayne County Airport to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Detroit Metropolitan Wayne County Airport to San Diego.

As of June 2026, prices for Detroit Metropolitan Wayne County Airport to San Diego flights are approximately 70% more expensive when compared to flights at the same time last year.

Southwest, Alaska Airlines, and United Airlines are the most popular carriers operating from Detroit Metropolitan Wayne County to San Diego

Delta, Frontier and Southwest are the top three most popular airlines that fly to San Diego from Detroit Metropolitan Wayne County Airport according to our data. Delta is the first choice among our users, with 61% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 6 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

Chicago (ORD) was the most common stop: 33% of momondo users choosing 1-stop flights on this route connected there.

Flights via Denver (DEN) offer the lowest average round-trip price of $165.

Flights connecting via Chicago (ORD) have the shortest average one-way travel time: 6h 40m.

Chicago (ORD) has the shortest average layover time for this route: 0h 47m.

The number of flights available between Detroit Metropolitan Wayne County Airport and San Diego is 7 per day as of June 2026. The most frequent departure time is 4:00PM, with 64% of daily flights leaving in the afternoon.

The number of flights available between Detroit Metropolitan Wayne County Airport and San Diego is 53 per week as of June 2026. The most frequent departure day is Fri, with 19% of weekly flights leaving on this day.