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Cheap flights from Des Moines to Charlotte from $93

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Charlotte departing on 2/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Charlotte

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:32 pm - 6:57 pm
DSM
-
CLT
22h 25m1 stop
Multiple Airlines Logo
6:01 pm - 6:47 pm
CLT
-
DSM
49h 46m2 stops
$229Multiple Airlines
Thu, Feb 12 - Tue, Feb 17
Multiple Airlines Logo
2:58 pm - 9:17 pm
DSM
-
CLT
29h 19m1 stop
Multiple Airlines Logo
6:28 pm - 10:19 am
CLT
-
DSM
16h 51m2 stops
$249Multiple Airlines
Sun, Jan 25 - Sun, Feb 1
Multiple Airlines Logo
7:20 pm - 9:21 am
DSM
-
CLT
13h 01m1 stop
Multiple Airlines Logo
5:13 pm - 6:32 pm
CLT
-
DSM
26h 19m1 stop
$263Multiple Airlines
Fri, Feb 20 - Sun, Feb 22
Frontier Logo
7:17 pm - 1:51 pm
DSM
-
CLT
17h 34m2 stops
Frontier Logo
5:03 pm - 6:32 pm
CLT
-
DSM
26h 29m1 stop
$273Frontier
Mon, Feb 23 - Sun, Mar 1
Multiple Airlines Logo
11:09 am - 10:55 am
DSM
-
CLT
22h 46m2 stops
Multiple Airlines Logo
1:24 pm - 10:46 pm
CLT
-
DSM
10h 22m1 stop
$283Multiple Airlines
Mon, Jan 12 - Thu, Jan 15
Multiple Airlines Logo
2:58 pm - 9:17 pm
DSM
-
CLT
29h 19m1 stop
Multiple Airlines Logo
9:59 pm - 1:18 pm
CLT
-
DSM
16h 19m1 stop
$285Multiple Airlines
Sun, Jan 25 - Sun, Feb 1
Multiple Airlines Logo
7:20 pm - 9:21 am
DSM
-
CLT
13h 01m1 stop
Multiple Airlines Logo
6:01 pm - 6:42 pm
CLT
-
DSM
49h 41m2 stops
$295Multiple Airlines
Fri, Feb 20 - Tue, Feb 24
Multiple Airlines Logo
10:29 am - 11:56 pm
DSM
-
CLT
12h 27m2 stops
Multiple Airlines Logo
5:13 pm - 6:32 pm
CLT
-
DSM
26h 19m1 stop
$303Multiple Airlines
Fri, Feb 20 - Sun, Feb 22
Multiple Airlines Logo
2:58 pm - 10:17 am
DSM
-
CLT
18h 19m2 stops
Multiple Airlines Logo
7:43 pm - 10:19 am
CLT
-
DSM
15h 36m2 stops
$309Multiple Airlines
Sun, Jan 25 - Sun, Feb 1
American Airlines Logo
11:42 am - 8:52 pm
DSM
-
CLT
8h 10m1 stop
American Airlines Logo
7:50 am - 4:24 pm
CLT
-
DSM
9h 34m1 stop
$317American Airlines
Sat, Jan 17 - Tue, Jan 20

Delta flights from Des Moines to Charlotte

Our best Delta deals on Des Moines to Charlotte flight tickets
Delta
Jun 20
DSM6:30 pmDes Moines
4h 27m
1 stop
CLT11:57 pmCharlotte Douglas
Jul 1
CLT6:20 amCharlotte Douglas
4h 55m
1 stop
DSM10:15 amDes Moines
$393
Find similar
Delta
Jun 24
DSM5:45 amDes Moines
6h 45m
1 stop
CLT1:30 pmCharlotte Douglas
Jun 28
CLT5:30 amCharlotte Douglas
5h 44m
1 stop
DSM10:14 amDes Moines
$417
Find similar
Delta
Dec 31
DSM5:55 pmDes Moines
4h 42m
1 stop
CLT11:37 pmCharlotte Douglas
Jan 3
CLT6:20 amCharlotte Douglas
6h 08m
1 stop
DSM11:28 amDes Moines
$441
Find similar

Southwest flights from Des Moines to Charlotte

Our best Southwest deals on Des Moines to Charlotte flight tickets
Southwest
Feb 23
DSM6:25 amDes Moines
10h 15m
2 stops
CLT5:40 pmCharlotte Douglas
Feb 28
CLT10:45 amCharlotte Douglas
9h 30m
2 stops
DSM7:15 pmDes Moines
$364
Find similar
Southwest
Feb 12
DSM5:10 amDes Moines
6h 05m
2 stops
CLT12:15 pmCharlotte Douglas
Feb 17
CLT10:55 amCharlotte Douglas
11h 25m
2 stops
DSM9:20 pmDes Moines
$384
Find similar
Southwest
Apr 1
DSM3:40 pmDes Moines
4h 25m
1 stop
CLT9:05 pmCharlotte Douglas
Apr 7
CLT6:40 amCharlotte Douglas
8h 25m
2 stops
DSM2:05 pmDes Moines
$398
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 2/12

7:32 pm-6:57 pm

1 stop22h 25m

Charlotte Douglas

Tue 2/17

6:01 pm-6:47 pm

2 stops49h 46m

$229

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sun 1/25

2:58 pm-9:17 pm

1 stop29h 19m

Charlotte Douglas

Sun 2/1

6:28 pm-10:19 am

2 stops16h 51m

$249

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 2/20

7:20 pm-9:21 am

1 stop13h 01m

Charlotte Douglas

Sun 2/22

5:13 pm-6:32 pm

1 stop26h 19m

$263

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 2/23

7:17 pm-1:51 pm

2 stops17h 34m

Charlotte Douglas

Sun 3/1

5:03 pm-6:32 pm

1 stop26h 29m

$273

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 1/12

11:09 am-10:55 am

2 stops22h 46m

Charlotte Douglas

Thu 1/15

1:24 pm-10:46 pm

1 stop10h 22m

$283

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sun 1/25

2:58 pm-9:17 pm

1 stop29h 19m

Charlotte Douglas

Sun 2/1

9:59 pm-1:18 pm

1 stop16h 19m

$285

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 2/20

7:20 pm-9:21 am

1 stop13h 01m

Charlotte Douglas

Tue 2/24

6:01 pm-6:42 pm

2 stops49h 41m

$295

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 2/20

10:29 am-11:56 pm

2 stops12h 27m

Charlotte Douglas

Sun 2/22

5:13 pm-6:32 pm

1 stop26h 19m

$303

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sun 1/25

2:58 pm-10:17 am

2 stops18h 19m

Charlotte Douglas

Sun 2/1

7:43 pm-10:19 am

2 stops15h 36m

$309

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 1/17

11:42 am-8:52 pm

1 stop8h 10m

Charlotte Douglas

Tue 1/20

7:50 am-4:24 pm

1 stop9h 34m

$317

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Charlotte from

How to get the cheapest flight ticket from Des Moines to Charlotte

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Charlotte?

The cheapest month to fly to Charlotte from Des Moines is in February. Flight prices, which tend to average around $374, are often lower during this time because this is during the off-season. If you are unable to visit Charlotte during the month of February, then departing from Des Moines during the month April is also very affordable. Most momondo users find prices during this month for around $386.

What is the cheapest day to depart on your flight to Charlotte?

The cheapest day to depart on your flight to Charlotte is on a Wednesday when prices can be found for as low as $386. This is often the case because there is less demand to fly during this day of the week. The most expensive day to fly to Charlotte is Sunday, with ticket prices averaging around $542.

What is the cheapest time of day to depart on your flight to Charlotte?

Flying to Charlotte from Des Moines in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $380 when looking at flights departing in the afternoon. In contrast, the most expensive time of day to depart to Charlotte is in the morning when prices are around $483.

What is the cheapest Des Moines to Charlotte Douglas flight route?

Fly from Des Moines to Charlotte Douglas for the best Des Moines - Charlotte Douglas flight prices

How far in advance should I book a flight to Charlotte?

You are more likely to see cheaper flights to Charlotte from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Charlotte for around $428 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Charlotte from Des Moines for as low as $230 on momondo.

What cabin class options are available on Des Moines to Charlotte Douglas flights?

There are 3 cabin classes available to choose from on Des Moines to Charlotte Douglas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Charlotte flights?

You could potentially save up to 66% on your flight if you consider stops on a Des Moines to Charlotte flight.

How have Des Moines to Charlotte flight prices changed over time?

When to book flights from Des Moines to Charlotte

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Charlotte according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Charlotte (DSM to CLT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Charlotte

Best Price Found

$229

Fastest flight time

2h 15m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun

Airports in Charlotte

1 airport
The best one-way flight to Charlotte from Des Moines in the past 72 hours is $229. The best round-trip flight deal from Des Moines to Charlotte found on momondo in the last 72 hours is $396.
The fastest flight from Des Moines to Charlotte takes 2h 15m
Direct flights go from Des Moines to Charlotte on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport in Charlotte. From Des Moines there are direct flights to Charlotte Douglas (CLT).
Search flight deals

  • How far is Des Moines to Charlotte Douglas by plane?

    The distance between Des Moines and Charlotte Douglas is about 818.0 mi. In terms of flight time, this usually takes a little over 2h 15m.

  • When did momondo last update prices for flights from Des Moines Airport to Charlotte Douglas Airport?

    Prices for flights from Des Moines Airport to Charlotte Douglas Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Charlotte Douglas Airport?

  • How old do you have to be to fly from Des Moines Airport to Charlotte Douglas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Charlotte Douglas Airport.

  • What documentation or ID do you need to fly to Charlotte Douglas Airport?

    The travel and health documents required for your trip to Charlotte Douglas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Charlotte Douglas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Des Moines to Charlotte?

  • What is the most popular airline from Des Moines to Charlotte?

Best airlines flying from Des Moines to Charlotte

Compare and see reviews for airlines that fly from Des Moines to Charlotte with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $216Free CancellationRating
7.9
8,019 reviews
Search Delta flights
American AirlinesPriceFrom $324Free CancellationRating
7.2
11,072 reviews
Search American Airlines flights

  • American Airlines Flights From Des Moines to Charlotte

    The lowest priced American Airlines flight from Des Moines to Charlotte from the last 72 hours was $324. Generally, American Airlines has 14 flights on this route every week with an average price of $422. American Airlines is rated 7.2/10 by our users.

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Spartanburg
Rock Hill
Boone
Gastonia
Hickory
Blowing Rock
Mooresville
Salisbury
Kannapolis
Pineville
Statesville
Huntersville
Shelby
Fort Mill
Gaffney
Kings Mountain
Matthews
Morganton
Cornelius
Lancaster

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Charlotte?

It is quick and easy to find Des Moines to Charlotte flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charlotte that suits you.

Can I find flights from Des Moines to Charlotte with flexible booking policies on momondo?

All flight searches from Des Moines to Charlotte on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Charlotte?

Once all potential Des Moines to Charlotte flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Charlotte right now. Can momondo alert me if prices change?

Price alerts on flights to Charlotte from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Charlotte trip

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