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Cheap flights from Des Moines to Charlotte from $118

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Charlotte departing on 10/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Charlotte

Cheap round-trip flights

Logo
4:29 pm - 8:05 amDSM-CLT
14h 36m2 stops
Logo
2:52 pm - 8:41 pmCLT-DSM
6h 49m1 stop
$220
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Fri, Aug 22 - Mon, Aug 25
Logo
2:22 pm - 9:22 amDSM-CLT
18h 00m2 stops
Logo
9:10 am - 2:40 pmCLT-DSM
6h 30m1 stop
$224
Find Deal
Mon, Sep 8 - Fri, Sep 12
Logo
8:00 am - 9:37 pmDSM-CLT
12h 37m1 stop
Logo
9:10 am - 2:40 pmCLT-DSM
6h 30m1 stop
$228
Find Deal
Mon, Sep 8 - Fri, Sep 12
Frontier Logo
3:30 pm - 4:32 pmDSM-CLT
24h 02m1 stop
Frontier Logo
5:34 pm - 7:59 pmCLT-DSM
27h 25m1 stop
$235Frontier
Find Deal
Wed, Oct 15 - Sun, Oct 19
Southwest Logo
4:45 pm - 9:30 pmDSM-CLT
3h 45m1 stop
Southwest Logo
6:25 pm - 11:35 pmCLT-DSM
6h 10m1 stop
$236Southwest
Find Deal
Tue, Oct 21 - Thu, Nov 6
Logo
2:12 pm - 9:22 amDSM-CLT
18h 10m2 stops
Logo
9:10 am - 2:40 pmCLT-DSM
6h 30m1 stop
$240
Find Deal
Fri, Sep 12 - Fri, Sep 19
Southwest Logo
8:35 am - 4:35 pmDSM-CLT
7h 00m1 stop
Southwest Logo
5:25 pm - 10:20 pmCLT-DSM
5h 55m1 stop
$242Southwest
Find Deal
Sat, Aug 30 - Wed, Sep 3
Frontier Logo
2:25 pm - 4:43 pmDSM-CLT
25h 18m1 stop
Frontier Logo
5:20 pm - 1:40 pmCLT-DSM
21h 20m1 stop
$245Frontier
Find Deal
Thu, Sep 25 - Sun, Sep 28
Frontier Logo
2:25 pm - 4:25 pmDSM-CLT
25h 00m1 stop
Frontier Logo
5:20 pm - 1:40 pmCLT-DSM
21h 20m1 stop
$247Frontier
Find Deal
Thu, Sep 11 - Thu, Sep 18
Southwest Logo
7:25 am - 8:45 pmDSM-CLT
12h 20m1 stop
Southwest Logo
8:05 am - 9:50 pmCLT-DSM
14h 45m2 stops
$253Southwest
Find Deal
Sat, Oct 4 - Wed, Oct 8

American Airlines flights from Des Moines to Charlotte

Our best American Airlines deals on Des Moines to Charlotte flight tickets
American Airlines
Aug 9
DSM7:00 amDes Moines
2h 23m
CLT10:23 amCharlotte Douglas
Aug 12
CLT3:29 pmCharlotte Douglas
2h 19m
DSM4:48 pmDes Moines
$439
Find similar
American Airlines
Aug 9
DSM6:28 amDes Moines
6h 03m
1 stop
CLT1:31 pmCharlotte Douglas
Aug 12
CLT8:50 amCharlotte Douglas
2h 31m
DSM10:21 amDes Moines
$449
Find similar
American Airlines
Aug 9
DSM7:00 amDes Moines
2h 23m
CLT10:23 amCharlotte Douglas
Aug 12
CLT3:29 pmCharlotte Douglas
2h 19m
DSM4:48 pmDes Moines
$451
Find similar

United Airlines flights from Des Moines to Charlotte

Our best United Airlines deals on Des Moines to Charlotte flight tickets
United Airlines
Aug 13
DSM2:57 pmDes Moines
6h 00m
1 stop
CLT9:57 pmCharlotte Douglas
Aug 16
CLT11:15 amCharlotte Douglas
10h 09m
2 stops
DSM8:24 pmDes Moines
$464
Find similar
United Airlines
Aug 13
DSM6:24 amDes Moines
6h 43m
2 stops
CLT2:07 pmCharlotte Douglas
Aug 16
CLT2:48 pmCharlotte Douglas
7h 59m
2 stops
DSM9:47 pmDes Moines
$469
Find similar
United Airlines
Aug 9
DSM6:00 amDes Moines
10h 16m
2 stops
CLT5:16 pmCharlotte Douglas
Aug 12
CLT6:45 amCharlotte Douglas
4h 44m
1 stop
DSM10:29 amDes Moines
$534
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 8/22

4:29 pm-8:05 am

2 stops14h 36m

Charlotte Douglas

Mon 8/25

2:52 pm-8:41 pm

1 stop6h 49m

$220

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 9/8

2:22 pm-9:22 am

2 stops18h 00m

Charlotte Douglas

Fri 9/12

9:10 am-2:40 pm

1 stop6h 30m

$224

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 9/8

8:00 am-9:37 pm

1 stop12h 37m

Charlotte Douglas

Fri 9/12

9:10 am-2:40 pm

1 stop6h 30m

$228

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 10/15

3:30 pm-4:32 pm

1 stop24h 02m

Charlotte Douglas

Sun 10/19

5:34 pm-7:59 pm

1 stop27h 25m

$235

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 10/21

4:45 pm-9:30 pm

1 stop3h 45m

Charlotte Douglas

Thu 11/6

6:25 pm-11:35 pm

1 stop6h 10m

$236

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 9/12

2:12 pm-9:22 am

2 stops18h 10m

Charlotte Douglas

Fri 9/19

9:10 am-2:40 pm

1 stop6h 30m

$240

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 8/30

8:35 am-4:35 pm

1 stop7h 00m

Charlotte Douglas

Wed 9/3

5:25 pm-10:20 pm

1 stop5h 55m

$242

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 9/25

2:25 pm-4:43 pm

1 stop25h 18m

Charlotte Douglas

Sun 9/28

5:20 pm-1:40 pm

1 stop21h 20m

$245

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 9/11

2:25 pm-4:25 pm

1 stop25h 00m

Charlotte Douglas

Thu 9/18

5:20 pm-1:40 pm

1 stop21h 20m

$247

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 10/4

7:25 am-8:45 pm

1 stop12h 20m

Charlotte Douglas

Wed 10/8

8:05 am-9:50 pm

2 stops14h 45m

$253

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Charlotte from

How to get the cheapest flight ticket from Des Moines to Charlotte

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Charlotte?

The cheapest month to fly to Charlotte from Des Moines is in September. Flight prices, which tend to average around $371, are often lower during this time because this is during the off-season. If you are unable to visit Charlotte during the month of September, then departing from Des Moines during the month October is also very affordable. Most momondo users find prices during this month for around $371.

What is the cheapest day to depart on your flight to Charlotte?

The cheapest day to depart on your flight to Charlotte is on a Tuesday when prices can be found for as low as $388. This is often the case because there is less demand to fly during this day of the week. The most expensive day to fly to Charlotte is Sunday, with ticket prices averaging around $541.

What is the cheapest time of day to depart on your flight to Charlotte?

Flying to Charlotte from Des Moines in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $368 when looking at flights departing in the afternoon. In contrast, the most expensive time of day to depart to Charlotte is in the morning when prices are around $488.

What is the cheapest Des Moines to Charlotte Douglas flight route?

Fly from Des Moines to Charlotte Douglas for the best Des Moines - Charlotte Douglas flight prices

How far in advance should I book a flight to Charlotte?

You are more likely to see cheaper flights to Charlotte from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Charlotte for around $401 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Charlotte from Des Moines for as low as $230 on momondo.

What cabin class options are available on Des Moines to Charlotte Douglas flights?

There are 3 cabin classes available to choose from on Des Moines to Charlotte Douglas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Charlotte flights?

You could potentially save up to 54% on your flight if you consider stops on a Des Moines to Charlotte flight.

How have Des Moines to Charlotte flight prices changed over time?

When to book flights from Des Moines to Charlotte

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Charlotte according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Charlotte (DSM to CLT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Charlotte

Best Price Found

$118

Fastest flight time

2h 26m

Direct flights

Every day

Airports in Charlotte

1 airport
The best one-way flight to Charlotte from Des Moines in the past 72 hours is $118. The best round-trip flight deal from Des Moines to Charlotte found on momondo in the last 72 hours is $220.
The fastest flight from Des Moines to Charlotte takes 2h 26m
Direct flights go from Des Moines to Charlotte every day.
There is 1 airport near Charlotte: Charlotte Douglas (CLT)
Search flight deals

  • How far is Des Moines to Charlotte Douglas by plane?

    The distance between Des Moines and Charlotte Douglas is about 818.0 mi. In terms of flight time, this usually takes a little over 3h 45m.

  • When did momondo last update prices for flights from Des Moines Airport to Charlotte Douglas Airport?

    Prices for flights from Des Moines Airport to Charlotte Douglas Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Charlotte Douglas Airport?

  • How old do you have to be to fly from Des Moines Airport to Charlotte Douglas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Charlotte Douglas Airport.

  • What documentation or ID do you need to fly to Charlotte Douglas Airport?

    The travel and health documents required for your trip to Charlotte Douglas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Charlotte Douglas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Des Moines to Charlotte?

  • What is the most popular airline from Des Moines to Charlotte?

Best airlines flying from Des Moines to Charlotte

Compare and see reviews for airlines that fly from Des Moines to Charlotte with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $131Free CancellationRating
8.0
7,981 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

  • American Airlines Flights From Des Moines to Charlotte

    The lowest priced American Airlines flight from Des Moines to Charlotte from the last 72 hours was $258. Generally, American Airlines has 11 flights on this route every week with an average price of $401. American Airlines is rated 7.2/10 by our users.

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Spartanburg
Rock Hill
Gastonia
Boone
Blowing Rock
Hickory
Mooresville
Salisbury
Kannapolis
Kings Mountain
Shelby
Pineville
Fort Mill
Statesville
Gaffney
Huntersville
Matthews
Morganton
Cornelius
Lancaster

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Charlotte?

It is quick and easy to find Des Moines to Charlotte flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charlotte that suits you.

Can I find flights from Des Moines to Charlotte with flexible booking policies on momondo?

All flight searches from Des Moines to Charlotte on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Charlotte?

Once all potential Des Moines to Charlotte flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Charlotte right now. Can momondo alert me if prices change?

Price alerts on flights to Charlotte from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Charlotte trip

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