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Cheap flights from Des Moines to Charlotte from $113

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Charlotte departing on 12/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Multiple Airlines Logo
2:56 pm - 11:59 pmDSM-CLT
8h 03m1 stop
Multiple Airlines Logo
3:07 pm - 7:44 pmCLT-DSM
29h 37m2 stops
$239Multiple Airlines
Find Deal
Thu, Dec 11 - Thu, Dec 18
Multiple Airlines Logo
9:19 am - 2:05 pmDSM-CLT
27h 46m1 stop
Multiple Airlines Logo
8:00 pm - 7:01 pmCLT-DSM
48h 01m2 stops
$250Multiple Airlines
Find Deal
Thu, Nov 20 - Sun, Nov 23
Multiple Airlines Logo
9:19 am - 2:05 pmDSM-CLT
27h 46m1 stop
Multiple Airlines Logo
10:16 pm - 1:31 pmCLT-DSM
40h 15m2 stops
$263Multiple Airlines
Find Deal
Thu, Nov 20 - Sun, Nov 23
Multiple Airlines Logo
10:38 am - 7:57 amDSM-CLT
20h 19m1 stop
Multiple Airlines Logo
3:07 pm - 7:03 pmCLT-DSM
28h 56m2 stops
$271Multiple Airlines
Find Deal
Sat, Dec 13 - Sun, Dec 14
Multiple Airlines Logo
10:38 am - 7:57 amDSM-CLT
20h 19m1 stop
Multiple Airlines Logo
5:44 pm - 7:03 pmCLT-DSM
26h 19m1 stop
$274Multiple Airlines
Find Deal
Sat, Dec 13 - Sun, Dec 14
Multiple Airlines Logo
2:56 pm - 11:59 pmDSM-CLT
8h 03m1 stop
Multiple Airlines Logo
7:00 am - 10:36 pmCLT-DSM
16h 36m1 stop
$281Multiple Airlines
Find Deal
Thu, Dec 11 - Thu, Dec 18
Multiple Airlines Logo
9:00 am - 7:57 amDSM-CLT
21h 57m1 stop
Multiple Airlines Logo
8:10 pm - 12:35 pmCLT-DSM
41h 25m2 stops
$284Multiple Airlines
Find Deal
Fri, Dec 5 - Mon, Dec 8
Multiple Airlines Logo
3:45 pm - 9:39 amDSM-CLT
16h 54m1 stop
Multiple Airlines Logo
10:38 pm - 7:44 pmCLT-DSM
46h 06m2 stops
$289Multiple Airlines
Find Deal
Tue, Dec 30 - Sat, Jan 3
Multiple Airlines Logo
6:35 am - 12:04 pmDSM-CLT
28h 29m1 stop
Multiple Airlines Logo
9:34 pm - 2:42 pmCLT-DSM
18h 08m1 stop
$290Multiple Airlines
Find Deal
Mon, Dec 15 - Fri, Dec 19
Multiple Airlines Logo
9:51 am - 7:18 amDSM-CLT
20h 27m1 stop
Multiple Airlines Logo
10:16 pm - 2:40 pmCLT-DSM
41h 24m2 stops
$294Multiple Airlines
Find Deal
Thu, Nov 27 - Mon, Dec 1

American Airlines flights from Des Moines to Charlotte

Our best American Airlines deals on Des Moines to Charlotte flight tickets
American Airlines
Dec 13
DSM6:28 pmDes Moines
14h 49m
1 stop
CLT10:17 amCharlotte Douglas
Dec 14
CLT1:57 pmCharlotte Douglas
2h 40m
DSM3:37 pmDes Moines
$305
Find similar
American Airlines
Jan 17
DSM11:42 amDes Moines
10h 11m
1 stop
CLT10:53 pmCharlotte Douglas
Jan 20
CLT10:18 pmCharlotte Douglas
13h 54m
1 stop
DSM11:12 amDes Moines
$317
Find similar
American Airlines
Nov 22
DSM4:16 pmDes Moines
2h 31m
CLT7:47 pmCharlotte Douglas
Nov 22
CLT10:33 pmCharlotte Douglas
10h 48m
1 stop
DSM8:21 amDes Moines
$349
Find similar

Southwest flights from Des Moines to Charlotte

Our best Southwest deals on Des Moines to Charlotte flight tickets
Southwest
Dec 3
DSM6:15 amDes Moines
9h 05m
2 stops
CLT4:20 pmCharlotte Douglas
Dec 10
CLT7:00 amCharlotte Douglas
13h 55m
2 stops
DSM7:55 pmDes Moines
$371
Find similar
Southwest
Dec 3
DSM6:15 amDes Moines
10h 25m
1 stop
CLT5:40 pmCharlotte Douglas
Dec 10
CLT12:55 pmCharlotte Douglas
9h 40m
1 stop
DSM9:35 pmDes Moines
$372
Find similar
Southwest
Jan 7
DSM8:35 amDes Moines
8h 55m
1 stop
CLT6:30 pmCharlotte Douglas
Jan 19
CLT12:55 pmCharlotte Douglas
9h 25m
1 stop
DSM9:20 pmDes Moines
$374
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 12/11

2:56 pm-11:59 pm

1 stop8h 03m

Charlotte Douglas

Thu 12/18

3:07 pm-7:44 pm

2 stops29h 37m

$239

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 11/20

9:19 am-2:05 pm

1 stop27h 46m

Charlotte Douglas

Sun 11/23

8:00 pm-7:01 pm

2 stops48h 01m

$250

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 11/20

9:19 am-2:05 pm

1 stop27h 46m

Charlotte Douglas

Sun 11/23

10:16 pm-1:31 pm

2 stops40h 15m

$263

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 12/13

10:38 am-7:57 am

1 stop20h 19m

Charlotte Douglas

Sun 12/14

3:07 pm-7:03 pm

2 stops28h 56m

$271

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 12/13

10:38 am-7:57 am

1 stop20h 19m

Charlotte Douglas

Sun 12/14

5:44 pm-7:03 pm

1 stop26h 19m

$274

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 12/11

2:56 pm-11:59 pm

1 stop8h 03m

Charlotte Douglas

Thu 12/18

7:00 am-10:36 pm

1 stop16h 36m

$281

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 12/5

9:00 am-7:57 am

1 stop21h 57m

Charlotte Douglas

Mon 12/8

8:10 pm-12:35 pm

2 stops41h 25m

$284

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Tue 12/30

3:45 pm-9:39 am

1 stop16h 54m

Charlotte Douglas

Sat 1/3

10:38 pm-7:44 pm

2 stops46h 06m

$289

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 12/15

6:35 am-12:04 pm

1 stop28h 29m

Charlotte Douglas

Fri 12/19

9:34 pm-2:42 pm

1 stop18h 08m

$290

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 11/27

9:51 am-7:18 am

1 stop20h 27m

Charlotte Douglas

Mon 12/1

10:16 pm-2:40 pm

2 stops41h 24m

$294

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Charlotte from

How to get the cheapest flight ticket from Des Moines to Charlotte

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Charlotte?

The cheapest month to fly to Charlotte from Des Moines is in February. Flight prices, which tend to average around $374, are often lower during this time because this is during the off-season. If you are unable to visit Charlotte during the month of February, then departing from Des Moines during the month April is also very affordable. Most momondo users find prices during this month for around $386.

What is the cheapest day to depart on your flight to Charlotte?

The cheapest day to depart on your flight to Charlotte is on a Wednesday when prices can be found for as low as $390. This is often the case because there is less demand to fly during this day of the week. The most expensive day to fly to Charlotte is Sunday, with ticket prices averaging around $542.

What is the cheapest time of day to depart on your flight to Charlotte?

Flying to Charlotte from Des Moines in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $379 when looking at flights departing in the afternoon. In contrast, the most expensive time of day to depart to Charlotte is in the morning when prices are around $491.

What is the cheapest Des Moines to Charlotte Douglas flight route?

Fly from Des Moines to Charlotte Douglas for the best Des Moines - Charlotte Douglas flight prices

How far in advance should I book a flight to Charlotte?

You are more likely to see cheaper flights to Charlotte from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Charlotte for around $425 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Charlotte from Des Moines for as low as $230 on momondo.

What cabin class options are available on Des Moines to Charlotte Douglas flights?

There are 3 cabin classes available to choose from on Des Moines to Charlotte Douglas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Charlotte flights?

You could potentially save up to 35% on your flight if you consider stops on a Des Moines to Charlotte flight.

When to book flights from Des Moines to Charlotte

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Charlotte according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Charlotte (DSM to CLT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Charlotte

Best Price Found

$175

Fastest flight time

2h 18m

Direct flights

Every day

Airports in Charlotte

1 airport
The best one-way flight to Charlotte from Des Moines in the past 72 hours is $175. The best round-trip flight deal from Des Moines to Charlotte found on momondo in the last 72 hours is $348.
The fastest flight from Des Moines to Charlotte takes 2h 18m
Direct flights go from Des Moines to Charlotte every day.
There is 1 airport near Charlotte: Charlotte Douglas (CLT)
Search flight deals

  • How far is Des Moines to Charlotte Douglas by plane?

    The distance between Des Moines and Charlotte Douglas is about 818.0 mi. In terms of flight time, this usually takes a little over 2h 23m.

  • When did momondo last update prices for flights from Des Moines Airport to Charlotte Douglas Airport?

    Prices for flights from Des Moines Airport to Charlotte Douglas Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Charlotte Douglas Airport?

  • How old do you have to be to fly from Des Moines Airport to Charlotte Douglas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Charlotte Douglas Airport.

  • What documentation or ID do you need to fly to Charlotte Douglas Airport?

    The travel and health documents required for your trip to Charlotte Douglas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Charlotte Douglas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Des Moines to Charlotte?

  • What is the most popular airline from Des Moines to Charlotte?

Best airlines flying from Des Moines to Charlotte

Compare and see reviews for airlines that fly from Des Moines to Charlotte with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $216Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $318Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights

  • American Airlines Flights From Des Moines to Charlotte

    The lowest priced American Airlines flight from Des Moines to Charlotte from the last 72 hours was $318. Generally, American Airlines has 21 flights on this route every week with an average price of $425. American Airlines is rated 7.2/10 by our users.

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Spartanburg
Rock Hill
Gastonia
Boone
Hickory
Blowing Rock
Mooresville
Salisbury
Kannapolis
Pineville
Shelby
Kings Mountain
Statesville
Fort Mill
Gaffney
Huntersville
Matthews
Morganton
Cornelius
Lancaster

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Charlotte?

It is quick and easy to find Des Moines to Charlotte flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charlotte that suits you.

Can I find flights from Des Moines to Charlotte with flexible booking policies on momondo?

All flight searches from Des Moines to Charlotte on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Charlotte?

Once all potential Des Moines to Charlotte flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Charlotte right now. Can momondo alert me if prices change?

Price alerts on flights to Charlotte from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Charlotte trip

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