Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Charlotte from $102

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Charlotte departing on 5/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Charlotte

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
2:04 pm - 4:56 pm
DSM
-
CLT
25h 52m
1 stop
Frontier Logo
5:20 pm - 1:31 pm
CLT
-
DSM
21h 11m
1 stop
$151Frontier
Fri, May 1 - Tue, May 5
Frontier Logo
2:04 pm - 4:56 pm
DSM
-
CLT
25h 52m
1 stop
Frontier Logo
5:20 pm - 1:31 pm
CLT
-
DSM
21h 11m
1 stop
$171Frontier
Fri, May 1 - Tue, May 5
Frontier Logo
2:04 pm - 6:54 pm
DSM
-
CLT
27h 50m
1 stop
Frontier Logo
6:18 pm - 1:09 pm
CLT
-
DSM
19h 51m
1 stop
$212Frontier
Mon, Apr 20 - Thu, Apr 23
Multiple Airlines Logo
5:02 pm - 9:57 am
DSM
-
CLT
15h 55m
1 stop
Multiple Airlines Logo
7:13 pm - 10:52 pm
CLT
-
DSM
28h 39m
1 stop
$214Multiple Airlines
Sun, Jun 14 - Sat, Jun 20
Frontier Logo
2:16 pm - 6:14 pm
DSM
-
CLT
26h 58m
1 stop
Frontier Logo
7:14 pm - 1:31 pm
CLT
-
DSM
19h 17m
1 stop
$236Frontier
Mon, Jun 1 - Thu, Jun 4
Multiple Airlines Logo
2:04 pm - 10:17 am
DSM
-
CLT
19h 13m
2 stops
Multiple Airlines Logo
12:50 pm - 10:06 pm
CLT
-
DSM
10h 16m
1 stop
$239Multiple Airlines
Mon, Apr 27 - Thu, Apr 30
Multiple Airlines Logo
4:41 pm - 12:03 pm
DSM
-
CLT
18h 22m
1 stop
Multiple Airlines Logo
12:29 pm - 11:24 pm
CLT
-
DSM
11h 55m
1 stop
$254Multiple Airlines
Thu, May 28 - Mon, Jun 1
Multiple Airlines Logo
2:04 pm - 4:35 pm
DSM
-
CLT
25h 31m
2 stops
Multiple Airlines Logo
8:56 am - 4:00 pm
CLT
-
DSM
8h 04m
1 stop
$257Multiple Airlines
Mon, Apr 20 - Thu, Apr 23
Multiple Airlines Logo
4:41 pm - 12:03 pm
DSM
-
CLT
18h 22m
1 stop
Multiple Airlines Logo
10:58 am - 10:31 pm
CLT
-
DSM
12h 33m
1 stop
$258Multiple Airlines
Thu, May 21 - Sun, May 24
Multiple Airlines Logo
9:07 pm - 4:35 pm
DSM
-
CLT
18h 28m
2 stops
Multiple Airlines Logo
9:04 am - 4:00 pm
CLT
-
DSM
7h 56m
1 stop
$260Multiple Airlines
Mon, Apr 13 - Thu, Apr 16

Frontier flights from Des Moines to Charlotte

Our best Frontier deals on Des Moines to Charlotte flight tickets
Frontier
May 1
DSM2:04 pmDes Moines
25h 52m
1 stop
CLT4:56 pmCharlotte Douglas
May 5
CLT5:20 pmCharlotte Douglas
21h 11m
1 stop
DSM1:31 pmDes Moines
$151
Frontier
May 1
DSM2:04 pmDes Moines
25h 52m
1 stop
CLT4:56 pmCharlotte Douglas
May 5
CLT5:20 pmCharlotte Douglas
21h 11m
1 stop
DSM1:31 pmDes Moines
$171
Frontier
Apr 20
DSM2:04 pmDes Moines
27h 50m
1 stop
CLT6:54 pmCharlotte Douglas
Apr 23
CLT6:18 pmCharlotte Douglas
19h 51m
1 stop
DSM1:09 pmDes Moines
$212

American Airlines flights from Des Moines to Charlotte

Our best American Airlines deals on Des Moines to Charlotte flight tickets
American Airlines
Apr 15
DSM7:05 amDes Moines
2h 25m
CLT10:30 amCharlotte Douglas
Apr 18
CLT7:53 pmCharlotte Douglas
2h 34m
DSM9:27 pmDes Moines
$445
American Airlines
Apr 15
DSM7:05 amDes Moines
2h 25m
CLT10:30 amCharlotte Douglas
Apr 18
CLT2:13 pmCharlotte Douglas
6h 20m
1 stop
DSM7:33 pmDes Moines
$455
American Airlines
Apr 2
DSM1:52 pmDes Moines
2h 23m
CLT5:15 pmCharlotte Douglas
Apr 4
CLT11:30 amCharlotte Douglas
2h 37m
DSM1:07 pmDes Moines
$470

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Charlotte that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Des Moines to Charlotte that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 5/1

2:04 pm-4:56 pm

1 stop25h 52m

Charlotte Douglas

Tue 5/5

5:20 pm-1:31 pm

1 stop21h 11m

$151

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 5/1

2:04 pm-4:56 pm

1 stop25h 52m

Charlotte Douglas

Tue 5/5

5:20 pm-1:31 pm

1 stop21h 11m

$171

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 4/20

2:04 pm-6:54 pm

1 stop27h 50m

Charlotte Douglas

Thu 4/23

6:18 pm-1:09 pm

1 stop19h 51m

$212

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sun 6/14

5:02 pm-9:57 am

1 stop15h 55m

Charlotte Douglas

Sat 6/20

7:13 pm-10:52 pm

1 stop28h 39m

$214

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 6/1

2:16 pm-6:14 pm

1 stop26h 58m

Charlotte Douglas

Thu 6/4

7:14 pm-1:31 pm

1 stop19h 17m

$236

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 4/27

2:04 pm-10:17 am

2 stops19h 13m

Charlotte Douglas

Thu 4/30

12:50 pm-10:06 pm

1 stop10h 16m

$239

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 5/28

4:41 pm-12:03 pm

1 stop18h 22m

Charlotte Douglas

Mon 6/1

12:29 pm-11:24 pm

1 stop11h 55m

$254

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 4/20

2:04 pm-4:35 pm

2 stops25h 31m

Charlotte Douglas

Thu 4/23

8:56 am-4:00 pm

1 stop8h 04m

$257

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Thu 5/21

4:41 pm-12:03 pm

1 stop18h 22m

Charlotte Douglas

Sun 5/24

10:58 am-10:31 pm

1 stop12h 33m

$258
Quickest round-trip

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 4/13

9:07 pm-4:35 pm

2 stops18h 28m

Charlotte Douglas

Thu 4/16

9:04 am-4:00 pm

1 stop7h 56m

$260

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Charlotte from

How to get the cheapest flight ticket from Des Moines to Charlotte

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Charlotte?

What is the cheapest month to fly to Charlotte?

The cheapest month to fly to Charlotte from Des Moines is in September. Flight prices, which tend to average around $374, are often lower during this time because this is during the off-season. If you are unable to visit Charlotte during the month of September, then departing from Des Moines during the month April is also very affordable. Most momondo users find prices during this month for around $395.

What is the cheapest day to depart on your flight to Charlotte?

The cheapest day to depart on your flight to Charlotte is on a Wednesday when prices can be found for as low as $389. This is often the case because there is less demand to fly during this day of the week. The most expensive day to fly to Charlotte is Sunday, with ticket prices averaging around $524.

What is the cheapest time of day to depart on your flight to Charlotte?

Flying to Charlotte from Des Moines in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $374 when looking at flights departing in the afternoon. In contrast, the most expensive time of day to depart to Charlotte is in the morning when prices are around $470.

What is the cheapest Des Moines to Charlotte Douglas flight route?

Fly from Des Moines to Charlotte Douglas for the best Des Moines - Charlotte Douglas flight prices

How far in advance should I book a flight to Charlotte?

You are more likely to see cheaper flights to Charlotte from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Charlotte for around $450 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Charlotte from Des Moines for as low as $315 on momondo.

What cabin class options are available on Des Moines to Charlotte Douglas flights?

There are 3 cabin classes available to choose from on Des Moines to Charlotte Douglas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Des Moines to Charlotte flights?

You could potentially save up to 59% on your flight if you consider stops on a Des Moines to Charlotte flight.

How have Des Moines to Charlotte flight prices changed over time?

As of April 2026, prices for Des Moines to Charlotte flights are approximately 26% more expensive when compared to flights at the same time last year.

When to book flights from Des Moines to Charlotte

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Charlotte according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Charlotte (DSM to CLT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Charlotte

Best Price Found

$233

Fastest flight time

2h 25m

Direct flights

Every day

Airports in Charlotte

1 airport
The best one-way flight to Charlotte from Des Moines in the past 72 hours is $233. The best round-trip flight deal from Des Moines to Charlotte found on momondo in the last 72 hours is $407.
The fastest flight from Des Moines to Charlotte takes 2h 25m
Direct flights go from Des Moines to Charlotte every day.
There is 1 airport in Charlotte. From Des Moines there are direct flights to Charlotte Douglas (CLT).
Search flight deals

Frequently asked questions about flying from Des Moines to Charlotte

  • How far is Des Moines to Charlotte Douglas by plane?

    The distance between Des Moines and Charlotte Douglas is about 818.0 mi. In terms of flight time, this usually takes a little over 2h 25m.

  • When did momondo last update prices for flights from Des Moines Airport to Charlotte Douglas Airport?

    Prices for flights from Des Moines Airport to Charlotte Douglas Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Charlotte Douglas Airport?

  • How old do you have to be to fly from Des Moines Airport to Charlotte Douglas Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Charlotte Douglas Airport.

  • What documentation or ID do you need to fly to Charlotte Douglas Airport?

    The travel and health documents required for your trip to Charlotte Douglas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Charlotte Douglas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Des Moines to Charlotte?

  • What is the most popular airline from Des Moines to Charlotte?

Best airlines flying from Des Moines to Charlotte

Compare and see reviews for airlines that fly from Des Moines to Charlotte with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $228Free CancellationRating
7.9
8,368 reviews
Search Delta flights
SouthwestPriceFrom $286Free CancellationRating
8.0
4,334 reviews
Search Southwest flights
American AirlinesPriceFrom $325Free CancellationRating
7.1
11,544 reviews
Search American Airlines flights

  • American Airlines Flights From Des Moines to Charlotte

    The lowest priced American Airlines flight from Des Moines to Charlotte from the last 72 hours was $325. Generally, American Airlines has 4 flights on this route every week with an average price of $440. American Airlines is rated 7.1/10 by our users.

Traveling to a place near Charlotte?

Book flights to Charlotte if you plan to visit one of these locations
Rock Hill
Spartanburg
Boone
Gastonia
Hickory
Blowing Rock
Salisbury
Statesville
Fort Mill
Mooresville
Huntersville
Kannapolis
Pineville
Gaffney
Matthews
Shelby
Morganton
Kings Mountain
Cornelius
Lancaster

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Charlotte?

It is quick and easy to find Des Moines to Charlotte flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charlotte that suits you.

Can I find flights from Des Moines to Charlotte with flexible booking policies on momondo?

All flight searches from Des Moines to Charlotte on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Charlotte?

Once all potential Des Moines to Charlotte flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Charlotte right now. Can momondo alert me if prices change?

Price alerts on flights to Charlotte from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Charlotte trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 5/1
Fri 5/8
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States