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Cheap flights from Des Moines to Columbus from $112

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Columbus departing on 3/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Columbus

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:03 pm - 10:51 am
DSM
-
CMH
13h 48m
1 stop
American Airlines Logo
7:27 am - 10:26 am
CMH
-
DSM
3h 59m
1 stop
$283American Airlines
Tue, Apr 7 - Sat, Apr 11
American Airlines Logo
6:00 am - 2:12 pm
DSM
-
CMH
7h 12m
1 stop
American Airlines Logo
8:56 pm - 11:49 pm
CMH
-
DSM
3h 53m
1 stop
$284American Airlines
Wed, May 13 - Mon, May 18
Frontier Logo
8:21 pm - 12:56 pm
DSM
-
CMH
15h 35m
2 stops
Frontier Logo
7:33 pm - 7:16 pm
CMH
-
DSM
24h 43m
1 stop
$288Frontier
Sat, Mar 7 - Sun, Mar 15
Delta Logo
5:47 pm - 11:59 pm
DSM
-
CMH
5h 12m
1 stop
Delta Logo
11:10 am - 4:33 pm
CMH
-
DSM
6h 23m
1 stop
$305Delta
Wed, Apr 8 - Sat, Apr 11
Frontier Logo
8:21 pm - 5:38 pm
DSM
-
CMH
20h 17m
1 stop
Frontier Logo
7:33 pm - 7:16 pm
CMH
-
DSM
24h 43m
1 stop
$309Frontier
Sat, Mar 7 - Sun, Mar 15
United Airlines Logo
11:25 am - 4:56 pm
DSM
-
CMH
4h 31m
1 stop
United Airlines Logo
6:10 am - 2:25 pm
CMH
-
DSM
9h 15m
2 stops
$310United Airlines
Sat, Apr 11 - Tue, Apr 14
Southwest Logo
5:30 am - 12:30 pm
DSM
-
CMH
6h 00m
2 stops
Southwest Logo
6:35 am - 1:30 pm
CMH
-
DSM
7h 55m
1 stop
$315Southwest
Tue, Apr 7 - Sat, Apr 11
Southwest Logo
5:35 am - 9:55 am
DSM
-
CMH
3h 20m
1 stop
Southwest Logo
8:00 pm - 11:15 pm
CMH
-
DSM
4h 15m
1 stop
$325Southwest
Thu, Mar 5 - Mon, Mar 9
American Airlines Logo
3:26 pm - 10:48 pm
DSM
-
CMH
6h 22m
1 stop
American Airlines Logo
9:27 am - 1:05 pm
CMH
-
DSM
4h 38m
1 stop
$326American Airlines
Sat, Mar 21 - Wed, Mar 25
Southwest Logo
5:35 am - 12:40 pm
DSM
-
CMH
6h 05m
2 stops
Southwest Logo
8:00 pm - 11:15 pm
CMH
-
DSM
4h 15m
1 stop
$330Southwest
Thu, Mar 5 - Mon, Mar 9

Frontier flights from Des Moines to Columbus Airport

Our best Frontier deals on Des Moines to Columbus Airport flight tickets
Frontier
Mar 7
DSM8:21 pmDes Moines
15h 35m
2 stops
CMH12:56 pmColumbus
Mar 15
CMH7:33 pmColumbus
24h 43m
1 stop
DSM7:16 pmDes Moines
$288
Frontier
Mar 7
DSM8:21 pmDes Moines
20h 17m
1 stop
CMH5:38 pmColumbus
Mar 15
CMH7:33 pmColumbus
24h 43m
1 stop
DSM7:16 pmDes Moines
$309
Frontier
Feb 27
DSM7:59 pmDes Moines
13h 06m
2 stops
CMH10:05 amColumbus
Mar 1
CMH8:09 pmColumbus
23h 23m
1 stop
DSM6:32 pmDes Moines
$361

American Airlines flights from Des Moines to Columbus Airport

Our best American Airlines deals on Des Moines to Columbus Airport flight tickets
American Airlines
Apr 7
DSM8:03 pmDes Moines
13h 48m
1 stop
CMH10:51 amColumbus
Apr 11
CMH7:27 amColumbus
3h 59m
1 stop
DSM10:26 amDes Moines
$283
American Airlines
May 13
DSM6:00 amDes Moines
7h 12m
1 stop
CMH2:12 pmColumbus
May 18
CMH8:56 pmColumbus
3h 53m
1 stop
DSM11:49 pmDes Moines
$284
American Airlines
Mar 21
DSM3:26 pmDes Moines
6h 22m
1 stop
CMH10:48 pmColumbus
Mar 25
CMH9:27 amColumbus
4h 38m
1 stop
DSM1:05 pmDes Moines
$326

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Columbus Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Des Moines to Columbus Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Tue 4/7

8:03 pm-10:51 am

1 stop13h 48m

Columbus

Sat 4/11

7:27 am-10:26 am

1 stop3h 59m

$283

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Wed 5/13

6:00 am-2:12 pm

1 stop7h 12m

Columbus

Mon 5/18

8:56 pm-11:49 pm

1 stop3h 53m

$284

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Sat 3/7

8:21 pm-12:56 pm

2 stops15h 35m

Columbus

Sun 3/15

7:33 pm-7:16 pm

1 stop24h 43m

$288

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Wed 4/8

5:47 pm-11:59 pm

1 stop5h 12m

Columbus

Sat 4/11

11:10 am-4:33 pm

1 stop6h 23m

$305

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Sat 3/7

8:21 pm-5:38 pm

1 stop20h 17m

Columbus

Sun 3/15

7:33 pm-7:16 pm

1 stop24h 43m

$309

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Sat 4/11

11:25 am-4:56 pm

1 stop4h 31m

Columbus

Tue 4/14

6:10 am-2:25 pm

2 stops9h 15m

$310

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Tue 4/7

5:30 am-12:30 pm

2 stops6h 00m

Columbus

Sat 4/11

6:35 am-1:30 pm

1 stop7h 55m

$315

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Thu 3/5

5:35 am-9:55 am

1 stop3h 20m

Columbus

Mon 3/9

8:00 pm-11:15 pm

1 stop4h 15m

$325

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Sat 3/21

3:26 pm-10:48 pm

1 stop6h 22m

Columbus

Wed 3/25

9:27 am-1:05 pm

1 stop4h 38m

$326

Des MoinesColumbus

DSM - CMH

DSMCMH

Des Moines

Thu 3/5

5:35 am-12:40 pm

2 stops6h 05m

Columbus

Mon 3/9

8:00 pm-11:15 pm

1 stop4h 15m

$330

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Columbus from

How to get the cheapest flight ticket from Des Moines to Columbus Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Columbus Airport?

The month of March is, on average, the cheapest month to fly to Columbus Airport from Des Moines, with most prices found around $306. If you are unable to visit Columbus Airport during the month of March, then departing from Des Moines during the month June is also very affordable. Most momondo users find prices during this month for around $314.

How have Des Moines to Columbus Airport flight prices changed over time?

When to book flights from Des Moines to Columbus Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Columbus Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Columbus Airport (DSM to CMH) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Columbus Airport

Fastest flight time

3h 20m

Direct flights

None
The fastest flight from Des Moines to Columbus Airport takes 3h 20m
There are no direct flights from Des Moines to Columbus Airport. There are no popular flight routes from Des Moines to Columbus Airport.
Search flight deals

  • How far is Des Moines to Columbus by plane?

    Des Moines and Columbus are 571.6 mi apart from one another. Flights usually cover this in 3h 20m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Des Moines Airport to Columbus Airport?

    Prices for flights from Des Moines Airport to Columbus Airport were last updated today.

  • How many operators does momondo search for flights from Des Moines Airport to Columbus Airport?

  • How old do you have to be to fly from Des Moines Airport to Columbus Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Columbus Airport.

  • What documentation or ID do you need to fly to Columbus Airport?

    The travel and health documents required for your trip to Columbus Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Columbus Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Columbus Airport?

Best airlines flying from Des Moines to Columbus Airport

Compare and see reviews for airlines that fly from Des Moines to Columbus Airport with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $250Free CancellationRating
7.2
11,275 reviews
Search American Airlines flights
United AirlinesPriceFrom $250Free CancellationRating
7.4
9,283 reviews
Search United Airlines flights
DeltaPriceFrom $250Free CancellationRating
7.9
8,186 reviews
Search Delta flights
SouthwestPriceFrom $260Free CancellationRating
8.0
4,283 reviews
Search Southwest flights

Traveling to a place near Columbus?

Book flights to Columbus if you plan to visit one of these locations
Grove City
Hilliard
Reynoldsburg
Chillicothe
Zanesville
Logan
Lancaster
Worthington
Bellville
Marysville
Westerville
Gahanna
Milledgeville

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Columbus?

Finding the right flight to Columbus from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Columbus quick and easy, saving you time and money.

Can I find flights from Des Moines to Columbus with flexible booking policies on momondo?

Yes. All flights to Columbus from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Columbus?

momondo provides multiple filters to help you find the best flight to Columbus from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Columbus right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Columbus flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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