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Cheap flights from Columbia, Missouri to San Diego from $318

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to San Diego departing on 6/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Columbia, Missouri to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:47 pm - 11:48 pm
COU
-
SAN
7h 01m
1 stop
American Airlines Logo
10:45 pm - 10:06 am
SAN
-
COU
9h 21m
1 stop
$318American Airlines
Thu, Jun 11 - Tue, Jun 16
American Airlines Logo
7:26 pm - 11:59 pm
COU
-
SAN
6h 33m
1 stop
American Airlines Logo
10:45 pm - 10:01 am
SAN
-
COU
9h 16m
1 stop
$328American Airlines
Thu, Jul 16 - Tue, Jul 21
United Airlines Logo
3:25 pm - 12:31 am
COU
-
SAN
11h 06m
2 stops
United Airlines Logo
10:40 pm - 9:35 am
SAN
-
COU
8h 55m
1 stop
$334United Airlines
Sat, Jun 27 - Sat, Aug 22
American Airlines Logo
5:19 pm - 11:59 pm
COU
-
SAN
8h 40m
1 stop
American Airlines Logo
7:28 am - 6:02 pm
SAN
-
COU
8h 34m
1 stop
$353American Airlines
Sat, May 23 - Wed, May 27
American Airlines Logo
7:26 pm - 11:59 pm
COU
-
SAN
6h 33m
1 stop
American Airlines Logo
6:20 am - 4:49 pm
SAN
-
COU
8h 29m
1 stop
$358American Airlines
Sat, Jul 11 - Thu, Jul 16
American Airlines Logo
5:19 pm - 11:59 pm
COU
-
SAN
8h 40m
1 stop
American Airlines Logo
9:50 am - 10:25 pm
SAN
-
COU
10h 35m
2 stops
$359American Airlines
Sat, May 23 - Wed, May 27
United Airlines Logo
9:00 am - 2:50 pm
COU
-
SAN
7h 50m
1 stop
United Airlines Logo
8:45 am - 9:49 pm
SAN
-
COU
11h 04m
2 stops
$370United Airlines
Tue, Sep 15 - Sat, Sep 19
United Airlines Logo
10:16 am - 5:26 pm
COU
-
SAN
9h 10m
2 stops
United Airlines Logo
10:40 pm - 9:35 am
SAN
-
COU
8h 55m
1 stop
$373United Airlines
Fri, Aug 21 - Sat, Aug 22
United Airlines Logo
3:25 pm - 12:31 am
COU
-
SAN
11h 06m
2 stops
United Airlines Logo
11:00 am - 10:35 pm
SAN
-
COU
9h 35m
2 stops
$379United Airlines
Sat, Jun 27 - Sat, Aug 22
United Airlines Logo
5:00 am - 10:11 am
COU
-
SAN
7h 11m
1 stop
United Airlines Logo
12:37 pm - 12:33 am
SAN
-
COU
9h 56m
2 stops
$381United Airlines
Thu, Oct 1 - Mon, Oct 5

American Airlines flights from Columbia, Missouri to San Diego

Our best American Airlines deals on Columbia, Missouri to San Diego flight tickets
American Airlines
Jun 11
COU6:47 pmColumbia Regional
7h 01m
1 stop
SAN11:48 pmSan Diego
Jun 16
SAN10:45 pmSan Diego
9h 21m
1 stop
COU10:06 amColumbia Regional
$318
American Airlines
Jul 16
COU7:26 pmColumbia Regional
6h 33m
1 stop
SAN11:59 pmSan Diego
Jul 21
SAN10:45 pmSan Diego
9h 16m
1 stop
COU10:01 amColumbia Regional
$328
American Airlines
May 23
COU5:19 pmColumbia Regional
8h 40m
1 stop
SAN11:59 pmSan Diego
May 27
SAN7:28 amSan Diego
8h 34m
1 stop
COU6:02 pmColumbia Regional
$353

United Airlines flights from Columbia, Missouri to San Diego

Our best United Airlines deals on Columbia, Missouri to San Diego flight tickets
United Airlines
Jun 27
COU3:25 pmColumbia Regional
11h 06m
2 stops
SAN12:31 amSan Diego
Aug 22
SAN10:40 pmSan Diego
8h 55m
1 stop
COU9:35 amColumbia Regional
$334
United Airlines
Sep 15
COU9:00 amColumbia Regional
7h 50m
1 stop
SAN2:50 pmSan Diego
Sep 19
SAN8:45 amSan Diego
11h 04m
2 stops
COU9:49 pmColumbia Regional
$370
United Airlines
Aug 21
COU10:16 amColumbia Regional
9h 10m
2 stops
SAN5:26 pmSan Diego
Aug 22
SAN10:40 pmSan Diego
8h 55m
1 stop
COU9:35 amColumbia Regional
$373

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Columbia, Missouri to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Thu 6/11

6:47 pm-11:48 pm

1 stop7h 01m

San Diego

Tue 6/16

10:45 pm-10:06 am

1 stop9h 21m

$318

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Thu 7/16

7:26 pm-11:59 pm

1 stop6h 33m

San Diego

Tue 7/21

10:45 pm-10:01 am

1 stop9h 16m

$328

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Sat 6/27

3:25 pm-12:31 am

2 stops11h 06m

San Diego

Sat 8/22

10:40 pm-9:35 am

1 stop8h 55m

$334

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Sat 5/23

5:19 pm-11:59 pm

1 stop8h 40m

San Diego

Wed 5/27

7:28 am-6:02 pm

1 stop8h 34m

$353
Quickest round-trip

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Sat 7/11

7:26 pm-11:59 pm

1 stop6h 33m

San Diego

Thu 7/16

6:20 am-4:49 pm

1 stop8h 29m

$358

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Sat 5/23

5:19 pm-11:59 pm

1 stop8h 40m

San Diego

Wed 5/27

9:50 am-10:25 pm

2 stops10h 35m

$359

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Tue 9/15

9:00 am-2:50 pm

1 stop7h 50m

San Diego

Sat 9/19

8:45 am-9:49 pm

2 stops11h 04m

$370

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Fri 8/21

10:16 am-5:26 pm

2 stops9h 10m

San Diego

Sat 8/22

10:40 pm-9:35 am

1 stop8h 55m

$373

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Sat 6/27

3:25 pm-12:31 am

2 stops11h 06m

San Diego

Sat 8/22

11:00 am-10:35 pm

2 stops9h 35m

$379

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Thu 10/1

5:00 am-10:11 am

1 stop7h 11m

San Diego

Mon 10/5

12:37 pm-12:33 am

2 stops9h 56m

$381

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Columbia, Missouri to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Columbia, Missouri and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of April, then departing from Columbia, Missouri during the month February is also very affordable. Most momondo users find prices during this month for around $310.

When to book flights from Columbia, Missouri to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to San Diego (COU to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to San Diego

Fastest flight time

7h 11m

Direct flights

None
The fastest flight from Columbia, Missouri to San Diego takes 7h 11m
There are no direct flights from Columbia, Missouri to San Diego. There are no popular flight routes from Columbia, Missouri to San Diego.
Search flight deals

Frequently asked questions about flying from Columbia, Missouri to San Diego

  • How far is Columbia Regional to San Diego by plane?

    The distance between Columbia Regional and San Diego is about 1449.4 mi. Flights usually cover this in 7h 11m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbia Regional Airport to San Diego Airport?

    Prices for flights from Columbia Regional Airport to San Diego Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbia Regional Airport to San Diego Airport?

  • How old do you have to be to fly from Columbia Regional Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia, Missouri to San Diego?

Best airlines flying from Columbia, Missouri to San Diego

Compare and see reviews for airlines that fly from Columbia, Missouri to San Diego with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $258Free CancellationRating
7.4
9,699 reviews
Search United Airlines flights
American AirlinesPriceFrom $429Free CancellationRating
7.1
11,667 reviews
Search American Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
La Mesa
Imperial Beach
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to San Diego?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Columbia to San Diego for you.

Can I find flights from Columbia to San Diego with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Diego from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to San Diego?

momondo provides multiple filters to help you find the best flight to San Diego from Columbia. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbia to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Columbia and alert you when they change.

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