Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Columbia, Missouri to San Diego from $312

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to San Diego departing on 10/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Columbia, Missouri to San Diego

Cheap round-trip flights

United Airlines Logo
9:01 am - 9:12 amCOU-SAN
26h 11m1 stop
United Airlines Logo
6:30 pm - 8:25 pmSAN-COU
23h 55m1 stop
$455United Airlines
Find Deal
Mon, Oct 6 - Fri, Oct 10
United Airlines Logo
9:00 am - 10:29 pmCOU-SAN
15h 29m1 stop
United Airlines Logo
6:47 pm - 8:51 pmSAN-COU
24h 04m1 stop
$465United Airlines
Find Deal
Thu, Nov 13 - Sun, Nov 16
American Airlines Logo
11:41 am - 8:48 pmCOU-SAN
11h 07m1 stop
American Airlines Logo
6:19 am - 7:07 pmSAN-COU
10h 48m1 stop
$475American Airlines
Find Deal
Fri, Nov 7 - Mon, Nov 10
United Airlines Logo
8:00 am - 11:40 amCOU-SAN
29h 40m1 stop
United Airlines Logo
6:30 pm - 8:25 pmSAN-COU
23h 55m1 stop
$480United Airlines
Find Deal
Fri, Oct 10 - Mon, Oct 13
United Airlines Logo
8:00 am - 9:40 amCOU-SAN
27h 40m1 stop
United Airlines Logo
10:30 pm - 9:27 pmSAN-COU
20h 57m1 stop
$485United Airlines
Find Deal
Fri, Oct 10 - Mon, Oct 13
American Airlines Logo
1:49 pm - 7:29 pmCOU-SAN
7h 40m1 stop
American Airlines Logo
10:53 am - 9:31 pmSAN-COU
8h 38m1 stop
$490American Airlines
Find Deal
Fri, Oct 10 - Mon, Oct 13
United Airlines Logo
9:00 am - 9:14 amCOU-SAN
26h 14m1 stop
United Airlines Logo
8:40 pm - 2:26 pmSAN-COU
15h 46m2 stops
$495United Airlines
Find Deal
Thu, Nov 13 - Sun, Nov 16
American Airlines Logo
2:05 pm - 8:48 pmCOU-SAN
8h 43m1 stop
American Airlines Logo
12:50 pm - 10:39 pmSAN-COU
7h 49m2 stops
$496American Airlines
Find Deal
Fri, Nov 7 - Mon, Nov 10
United Airlines Logo
9:01 am - 11:41 pmCOU-SAN
16h 40m2 stops
United Airlines Logo
6:30 pm - 8:25 pmSAN-COU
23h 55m1 stop
$500United Airlines
Find Deal
Mon, Oct 6 - Fri, Oct 10
United Airlines Logo
2:52 pm - 9:40 amCOU-SAN
20h 48m1 stop
United Airlines Logo
8:39 pm - 2:17 pmSAN-COU
15h 38m2 stops
$504United Airlines
Find Deal
Fri, Oct 10 - Mon, Oct 13

American Airlines flights from Columbia, Missouri to San Diego

Our best American Airlines deals on Columbia, Missouri to San Diego flight tickets
American Airlines
Nov 7
COU11:41 amColumbia Regional
11h 07m
1 stop
SAN8:48 pmSan Diego
Nov 10
SAN6:19 amSan Diego
10h 48m
1 stop
COU7:07 pmColumbia Regional
$475
Find similar
American Airlines
Oct 10
COU1:49 pmColumbia Regional
7h 40m
1 stop
SAN7:29 pmSan Diego
Oct 13
SAN10:53 amSan Diego
8h 38m
1 stop
COU9:31 pmColumbia Regional
$490
Find similar
American Airlines
Nov 7
COU2:05 pmColumbia Regional
8h 43m
1 stop
SAN8:48 pmSan Diego
Nov 10
SAN12:50 pmSan Diego
7h 49m
2 stops
COU10:39 pmColumbia Regional
$496
Find similar

United Airlines flights from Columbia, Missouri to San Diego

Our best United Airlines deals on Columbia, Missouri to San Diego flight tickets
United Airlines
Oct 6
COU9:01 amColumbia Regional
26h 11m
1 stop
SAN9:12 amSan Diego
Oct 10
SAN6:30 pmSan Diego
23h 55m
1 stop
COU8:25 pmColumbia Regional
$455
Find similar
United Airlines
Nov 13
COU9:00 amColumbia Regional
15h 29m
1 stop
SAN10:29 pmSan Diego
Nov 16
SAN6:47 pmSan Diego
24h 04m
1 stop
COU8:51 pmColumbia Regional
$465
Find similar
United Airlines
Oct 10
COU8:00 amColumbia Regional
29h 40m
1 stop
SAN11:40 amSan Diego
Oct 13
SAN6:30 pmSan Diego
23h 55m
1 stop
COU8:25 pmColumbia Regional
$480
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 9, 2025.
Use the filters below to find and compare flights from Columbia, Missouri to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Mon 10/6

9:01 am-9:12 am

1 stop26h 11m

San Diego

Fri 10/10

6:30 pm-8:25 pm

1 stop23h 55m

$455

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Thu 11/13

9:00 am-10:29 pm

1 stop15h 29m

San Diego

Sun 11/16

6:47 pm-8:51 pm

1 stop24h 04m

$465

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Fri 11/7

11:41 am-8:48 pm

1 stop11h 07m

San Diego

Mon 11/10

6:19 am-7:07 pm

1 stop10h 48m

$475

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Fri 10/10

8:00 am-11:40 am

1 stop29h 40m

San Diego

Mon 10/13

6:30 pm-8:25 pm

1 stop23h 55m

$480

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Fri 10/10

8:00 am-9:40 am

1 stop27h 40m

San Diego

Mon 10/13

10:30 pm-9:27 pm

1 stop20h 57m

$485

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Fri 10/10

1:49 pm-7:29 pm

1 stop7h 40m

San Diego

Mon 10/13

10:53 am-9:31 pm

1 stop8h 38m

$490

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Thu 11/13

9:00 am-9:14 am

1 stop26h 14m

San Diego

Sun 11/16

8:40 pm-2:26 pm

2 stops15h 46m

$495

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Fri 11/7

2:05 pm-8:48 pm

1 stop8h 43m

San Diego

Mon 11/10

12:50 pm-10:39 pm

2 stops7h 49m

$496

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Mon 10/6

9:01 am-11:41 pm

2 stops16h 40m

San Diego

Fri 10/10

6:30 pm-8:25 pm

1 stop23h 55m

$500

ColumbiaSan Diego

COU - SAN

COUSAN

Columbia Regional

Fri 10/10

2:52 pm-9:40 am

1 stop20h 48m

San Diego

Mon 10/13

8:39 pm-2:17 pm

2 stops15h 38m

$504

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

See travel insights to San Diego from

How to get the cheapest flight ticket from Columbia, Missouri to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Columbia, Missouri to San Diego is on a Tuesday. Travelers who choose to depart for San Diego on a Tuesday will often find tickets for as low as $483. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $650. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the afternoon when flights can be purchased for as low as $569. Flights in the morning are often more expensive with an average ticket price of $620.

When to book flights from Columbia, Missouri to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to San Diego (COU to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to San Diego

Direct flights

None
There are no direct flights from Columbia, Missouri to San Diego. There are no popular flight routes from Columbia, Missouri to San Diego.
Search flight deals

  • How far is Columbia Regional to San Diego by plane?

    The distance between Columbia Regional and San Diego is about 1449.4 mi. Flights usually cover this in 7h 40m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Columbia Regional Airport to San Diego Airport?

    Prices for flights from Columbia Regional Airport to San Diego Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbia Regional Airport to San Diego Airport?

  • How old do you have to be to fly from Columbia Regional Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia, Missouri to San Diego?

Best airlines flying from Columbia, Missouri to San Diego

Compare and see reviews for airlines that fly from Columbia, Missouri to San Diego with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $429Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
La Mesa
National City
Imperial Beach
Poway
San Ysidro
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to San Diego?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Columbia to San Diego for you.

Can I find flights from Columbia to San Diego with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Diego from Columbia which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Columbia to San Diego?

momondo provides multiple filters to help you find the best flight to San Diego from Columbia. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Columbia to San Diego right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Diego, momondo offers a useful price alert feature which will track prices for flights to San Diego from Columbia and alert you when they change.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 10/9
Thu 10/16
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States