Cheap flights from Charlotte to San Diego from $125

If you are unable to visit San Diego during the month of October, then departing from Charlotte during the month September is also very affordable. Most momondo users find prices during this month for around $455.

The cheapest day to depart from Charlotte to San Diego is on a Saturday. Travelers who choose to depart for San Diego on a Saturday will often find tickets for as low as $456. If your travel schedule is flexible, try to avoid departing on a Monday because tickets tend to average around $553. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

The cheapest time of day to fly to San Diego is at noon when flights can be purchased for as low as $436. Flights in the evening are often more expensive with an average ticket price of $499.

Fly from Charlotte Douglas to San Diego for the best Charlotte Douglas - San Diego flight prices

You are more likely to see cheaper flights to San Diego from Charlotte when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $470 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Charlotte for as low as $383 on momondo.

There are 3 cabin classes available to choose from on Charlotte to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest is the most popular carrier operating from Charlotte Douglas to San Diego

American Airlines, Delta and Southwest are the top three most popular airlines that fly to San Diego from Charlotte according to our data. American Airlines is the first choice among our users, with 75% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 7 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

Dallas (DFW) was the most common stop: 70% of momondo users choosing 1-stop flights on this route connected there.

Flights via Denver (DEN) offer the lowest average round-trip price of $233.

Flights connecting via Nashville (BNA) have the shortest average one-way travel time: 7h 05m.

Nashville (BNA) has the shortest average layover time for this route: 0h 48m.

As of May 2026, there are 8 flights per day flying from Charlotte to San Diego. The most common time of day flights depart is 7:00PM, with 48% of flights taking off at noon.

58 flights are operational weekly from Charlotte to San Diego as of May 2026. The most popular departure day for this route is Mon, with 16% of flights per week taking off on this day.