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Cheap flights from Buffalo to Los Angeles from $178

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Los Angeles departing on 2/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Buffalo to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
2:35 pm - 7:10 pm
BUF
-
SNA
7h 35m
1 stop
Southwest Logo
12:25 pm - 10:00 pm
SNA
-
BUF
6h 35m
1 stop
$447Southwest
Sat, Feb 7 - Tue, Feb 10
Southwest Logo
2:35 pm - 7:10 pm
BUF
-
SNA
7h 35m
1 stop
Southwest Logo
6:55 pm - 8:05 am
SNA
-
BUF
10h 10m
2 stops
$452Southwest
Sat, Feb 7 - Tue, Feb 10
Southwest Logo
6:40 am - 1:10 pm
BUF
-
SNA
9h 30m
1 stop
Southwest Logo
6:45 am - 4:35 pm
SNA
-
BUF
6h 50m
1 stop
$457Southwest
Tue, Apr 21 - Sat, Apr 25
Southwest Logo
5:15 am - 12:10 pm
BUF
-
SNA
9h 55m
2 stops
Southwest Logo
9:00 am - 9:55 pm
SNA
-
BUF
9h 55m
2 stops
$458Southwest
Sat, Feb 7 - Tue, Feb 10
Southwest Logo
6:05 am - 1:10 pm
BUF
-
SNA
10h 05m
2 stops
Southwest Logo
6:45 am - 4:35 pm
SNA
-
BUF
6h 50m
1 stop
$462Southwest
Tue, Apr 21 - Sat, Apr 25
Southwest Logo
6:05 am - 1:10 pm
BUF
-
SNA
10h 05m
2 stops
Southwest Logo
7:15 am - 8:40 pm
SNA
-
BUF
10h 25m
2 stops
$468Southwest
Tue, Apr 21 - Sat, Apr 25
American Airlines Logo
1:45 pm - 9:14 pm
BUF
-
SNA
10h 29m
1 stop
American Airlines Logo
7:20 pm - 10:56 am
SNA
-
BUF
12h 36m
2 stops
$482American Airlines
Thu, Apr 23 - Mon, Apr 27
Delta Logo
6:00 am - 10:55 am
BUF
-
SNA
7h 55m
1 stop
Delta Logo
2:29 pm - 10:35 am
SNA
-
BUF
17h 06m
2 stops
$495Delta
Wed, May 13 - Sat, May 23
Delta Logo
6:15 am - 10:46 am
BUF
-
SNA
7h 31m
1 stop
Delta Logo
11:56 am - 11:46 pm
SNA
-
BUF
8h 50m
1 stop
$497Delta
Wed, Mar 18 - Tue, Mar 24
United Airlines Logo
2:54 pm - 9:58 pm
BUF
-
SNA
10h 04m
2 stops
United Airlines Logo
11:10 am - 11:15 pm
SNA
-
BUF
9h 05m
1 stop
$502United Airlines
Wed, Apr 22 - Fri, Apr 24

Delta flights from Buffalo to Santa Ana, California

Our best Delta deals on Buffalo to Santa Ana, California flight tickets
Delta
May 13
BUF6:00 amBuffalo
7h 55m
1 stop
SNA10:55 amSanta Ana J. Wayne/Orange Cnty
May 23
SNA2:29 pmSanta Ana J. Wayne/Orange Cnty
17h 06m
2 stops
BUF10:35 amBuffalo
$495
Delta
Mar 18
BUF6:15 amBuffalo
7h 31m
1 stop
SNA10:46 amSanta Ana J. Wayne/Orange Cnty
Mar 24
SNA11:56 amSanta Ana J. Wayne/Orange Cnty
8h 50m
1 stop
BUF11:46 pmBuffalo
$497
Delta
Apr 1
BUF6:15 amBuffalo
7h 31m
1 stop
SNA10:46 amSanta Ana J. Wayne/Orange Cnty
Apr 6
SNA9:20 pmSanta Ana J. Wayne/Orange Cnty
14h 54m
2 stops
BUF3:14 pmBuffalo
$512

American Airlines flights from Buffalo to Santa Ana, California

Our best American Airlines deals on Buffalo to Santa Ana, California flight tickets
American Airlines
Apr 23
BUF1:45 pmBuffalo
10h 29m
1 stop
SNA9:14 pmSanta Ana J. Wayne/Orange Cnty
Apr 27
SNA7:20 pmSanta Ana J. Wayne/Orange Cnty
12h 36m
2 stops
BUF10:56 amBuffalo
$482
American Airlines
Apr 23
BUF2:59 pmBuffalo
10h 08m
1 stop
SNA10:07 pmSanta Ana J. Wayne/Orange Cnty
Apr 27
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
7h 53m
1 stop
BUF6:38 pmBuffalo
$511
American Airlines
Apr 1
BUF6:34 amBuffalo
10h 23m
1 stop
SNA1:57 pmSanta Ana J. Wayne/Orange Cnty
Apr 6
SNA10:55 amSanta Ana J. Wayne/Orange Cnty
8h 46m
1 stop
BUF10:41 pmBuffalo
$517

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 13, 2026.
Use the filters below to find and compare flights from Buffalo to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Sat 2/7

2:35 pm-7:10 pm

1 stop7h 35m

Santa Ana J. Wayne/Orange Cnty

Tue 2/10

12:25 pm-10:00 pm

1 stop6h 35m

$447

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Sat 2/7

2:35 pm-7:10 pm

1 stop7h 35m

Santa Ana J. Wayne/Orange Cnty

Tue 2/10

6:55 pm-8:05 am

2 stops10h 10m

$452

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Tue 4/21

6:40 am-1:10 pm

1 stop9h 30m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

6:45 am-4:35 pm

1 stop6h 50m

$457

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Sat 2/7

5:15 am-12:10 pm

2 stops9h 55m

Santa Ana J. Wayne/Orange Cnty

Tue 2/10

9:00 am-9:55 pm

2 stops9h 55m

$458

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Tue 4/21

6:05 am-1:10 pm

2 stops10h 05m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

6:45 am-4:35 pm

1 stop6h 50m

$462

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Tue 4/21

6:05 am-1:10 pm

2 stops10h 05m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

7:15 am-8:40 pm

2 stops10h 25m

$468

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Thu 4/23

1:45 pm-9:14 pm

1 stop10h 29m

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

7:20 pm-10:56 am

2 stops12h 36m

$482

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Wed 5/13

6:00 am-10:55 am

1 stop7h 55m

Santa Ana J. Wayne/Orange Cnty

Sat 5/23

2:29 pm-10:35 am

2 stops17h 06m

$495

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Wed 3/18

6:15 am-10:46 am

1 stop7h 31m

Santa Ana J. Wayne/Orange Cnty

Tue 3/24

11:56 am-11:46 pm

1 stop8h 50m

$497

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Wed 4/22

2:54 pm-9:58 pm

2 stops10h 04m

Santa Ana J. Wayne/Orange Cnty

Fri 4/24

11:10 am-11:15 pm

1 stop9h 05m

$502

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Buffalo to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, August is the cheapest month to fly from Buffalo to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $404. If you aren’t able to travel during the month of August, then book flights to Santa Ana, California from Buffalo during May instead. Flights to Santa Ana, California in May, while not as cheap as those in August, still average around $408.

How have Buffalo to Santa Ana, California flight prices changed over time?

When to book flights from Buffalo to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Santa Ana, California (BUF to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Santa Ana, California

Fastest flight time

7h 31m

Direct flights

None
The fastest flight from Buffalo to Santa Ana, California takes 7h 31m
There are no direct flights from Buffalo to Santa Ana, California. There are no popular flight routes from Buffalo to Santa Ana, California.
Search flight deals

  • How far is Buffalo to Santa Ana J. Wayne/Orange Cnty by plane?

    Buffalo and Santa Ana J. Wayne/Orange Cnty are 2182.8 mi apart from one another. Typically, this will take 7h 31m by plane in normal conditions.

  • When did momondo last update prices for flights from Buffalo Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Buffalo Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from Buffalo Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Buffalo Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The required travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Buffalo to Santa Ana, California?

Best airlines flying from Buffalo to Santa Ana, California

Compare and see reviews for airlines that fly from Buffalo to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $379Free CancellationRating
7.2
11,118 reviews
Search American Airlines flights
United AirlinesPriceFrom $390Free CancellationRating
7.4
9,156 reviews
Search United Airlines flights
SouthwestPriceFrom $392Free CancellationRating
8.0
4,257 reviews
Search Southwest flights
DeltaPriceFrom $432Free CancellationRating
7.9
8,040 reviews
Search Delta flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Santa Ana?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Buffalo to Santa Ana. momondo saves you time and could save you money on your trip.

Can I find flights from Buffalo to Santa Ana with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Buffalo to Santa Ana flights to just show those with flexible booking policies.

How can momondo help me find flights from Buffalo to Santa Ana?

Once you have performed a search for Buffalo to Santa Ana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Buffalo to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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