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Cheap flights from Buffalo to Los Angeles from $176

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to Los Angeles departing on 3/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Buffalo to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:00 am - 1:49 pm
BUF
-
SNA
9h 49m
1 stop
American Airlines Logo
7:45 am - 6:38 pm
SNA
-
BUF
7h 53m
1 stop
$385American Airlines
Tue, Apr 21 - Sat, Apr 25
Delta Logo
12:50 pm - 9:54 pm
BUF
-
SNA
12h 04m
2 stops
Delta Logo
1:12 pm - 10:39 pm
SNA
-
BUF
6h 27m
1 stop
$390Delta
Tue, Apr 21 - Tue, May 5
Delta Logo
12:50 pm - 9:54 pm
BUF
-
SNA
12h 04m
2 stops
Delta Logo
6:58 pm - 9:45 am
SNA
-
BUF
11h 47m
2 stops
$395Delta
Tue, Apr 21 - Wed, May 6
American Airlines Logo
1:45 pm - 9:14 pm
BUF
-
SNA
10h 29m
1 stop
American Airlines Logo
7:20 pm - 10:51 am
SNA
-
BUF
12h 31m
2 stops
$396American Airlines
Wed, Apr 22 - Mon, Apr 27
Southwest Logo
8:20 am - 1:55 pm
BUF
-
SNA
8h 35m
2 stops
Southwest Logo
6:45 am - 4:35 pm
SNA
-
BUF
6h 50m
1 stop
$423Southwest
Tue, Apr 21 - Sat, Apr 25
Delta Logo
12:50 pm - 9:54 pm
BUF
-
SNA
12h 04m
2 stops
Delta Logo
9:20 pm - 9:45 am
SNA
-
BUF
9h 25m
1 stop
$424Delta
Tue, Apr 21 - Thu, May 7
United Airlines Logo
5:57 pm - 10:30 pm
BUF
-
SNA
7h 33m
1 stop
United Airlines Logo
1:21 pm - 11:10 pm
SNA
-
BUF
6h 49m
1 stop
$425United Airlines
Tue, Apr 21 - Sat, Apr 25
Southwest Logo
3:10 pm - 9:45 pm
BUF
-
SNA
9h 35m
2 stops
Southwest Logo
6:45 am - 6:00 pm
SNA
-
BUF
8h 15m
2 stops
$428Southwest
Tue, Apr 21 - Sat, Apr 25
Delta Logo
12:50 pm - 9:54 pm
BUF
-
SNA
12h 04m
2 stops
Delta Logo
6:49 pm - 9:45 am
SNA
-
BUF
11h 56m
2 stops
$429Delta
Tue, Apr 21 - Thu, May 7
American Airlines Logo
1:34 pm - 9:14 pm
BUF
-
SNA
10h 40m
1 stop
American Airlines Logo
9:51 am - 11:08 pm
SNA
-
BUF
10h 17m
2 stops
$430American Airlines
Tue, Apr 21 - Sat, Apr 25

American Airlines flights from Buffalo to Santa Ana

Our best American Airlines deals on Buffalo to Santa Ana flight tickets
American Airlines
Apr 21
BUF7:00 amBuffalo
9h 49m
1 stop
SNA1:49 pmSanta Ana J. Wayne/Orange Cnty
Apr 25
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
7h 53m
1 stop
BUF6:38 pmBuffalo
$385
American Airlines
Apr 21
BUF1:34 pmBuffalo
10h 40m
1 stop
SNA9:14 pmSanta Ana J. Wayne/Orange Cnty
Apr 25
SNA9:51 amSanta Ana J. Wayne/Orange Cnty
10h 17m
2 stops
BUF11:08 pmBuffalo
$390
American Airlines
Apr 21
BUF5:00 amBuffalo
10h 32m
2 stops
SNA12:32 pmSanta Ana J. Wayne/Orange Cnty
Apr 25
SNA9:51 amSanta Ana J. Wayne/Orange Cnty
10h 17m
2 stops
BUF11:08 pmBuffalo
$395

Delta flights from Buffalo to Santa Ana

Our best Delta deals on Buffalo to Santa Ana flight tickets
Delta
Mar 18
BUF6:15 amBuffalo
7h 31m
1 stop
SNA10:46 amSanta Ana J. Wayne/Orange Cnty
Mar 24
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
11h 55m
2 stops
BUF10:55 pmBuffalo
$470
Delta
May 21
BUF10:32 amBuffalo
27h 38m
1 stop
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
May 30
SNA1:50 pmSanta Ana J. Wayne/Orange Cnty
16h 55m
2 stops
BUF9:45 amBuffalo
$520
Delta
Jun 24
BUF4:30 pmBuffalo
9h 08m
1 stop
SNA10:38 pmSanta Ana J. Wayne/Orange Cnty
Jun 29
SNA9:00 pmSanta Ana J. Wayne/Orange Cnty
10h 35m
1 stop
BUF10:35 amBuffalo
$568

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 26, 2026.
Use the filters below to find and compare flights from Buffalo to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Tue 4/21

7:00 am-1:49 pm

1 stop9h 49m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

7:45 am-6:38 pm

1 stop7h 53m

$385

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Tue 4/21

12:50 pm-9:54 pm

2 stops12h 04m

Santa Ana J. Wayne/Orange Cnty

Tue 5/5

1:12 pm-10:39 pm

1 stop6h 27m

$390

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Tue 4/21

12:50 pm-9:54 pm

2 stops12h 04m

Santa Ana J. Wayne/Orange Cnty

Wed 5/6

6:58 pm-9:45 am

2 stops11h 47m

$395

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Wed 4/22

1:45 pm-9:14 pm

1 stop10h 29m

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

7:20 pm-10:51 am

2 stops12h 31m

$396

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Tue 4/21

8:20 am-1:55 pm

2 stops8h 35m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

6:45 am-4:35 pm

1 stop6h 50m

$423

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Tue 4/21

12:50 pm-9:54 pm

2 stops12h 04m

Santa Ana J. Wayne/Orange Cnty

Thu 5/7

9:20 pm-9:45 am

1 stop9h 25m

$424

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Tue 4/21

5:57 pm-10:30 pm

1 stop7h 33m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

1:21 pm-11:10 pm

1 stop6h 49m

$425

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Tue 4/21

3:10 pm-9:45 pm

2 stops9h 35m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

6:45 am-6:00 pm

2 stops8h 15m

$428

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Tue 4/21

12:50 pm-9:54 pm

2 stops12h 04m

Santa Ana J. Wayne/Orange Cnty

Thu 5/7

6:49 pm-9:45 am

2 stops11h 56m

$429

BuffaloSanta Ana

BUF - SNA

BUFSNA

Buffalo

Tue 4/21

1:34 pm-9:14 pm

1 stop10h 40m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

9:51 am-11:08 pm

2 stops10h 17m

$430

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from Buffalo to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from Buffalo is in August. Flight prices, which tend to average around $404, are often lower during this time because this is during the off-season. The month of May is another great option to travel to Santa Ana, with average flight prices from Buffalo averaging around $408.

How have Buffalo to Santa Ana flight prices changed over time?

When to book flights from Buffalo to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to Santa Ana (BUF to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to Santa Ana

Fastest flight time

7h 07m

Direct flights

None
The fastest flight from Buffalo to Santa Ana takes 7h 07m
There are no direct flights from Buffalo to Santa Ana. There are no popular flight routes from Buffalo to Santa Ana.
Search flight deals

  • How far is Buffalo to Santa Ana J. Wayne/Orange Cnty by plane?

    Buffalo and Santa Ana J. Wayne/Orange Cnty are 2182.8 mi apart from one another. Typically, this will take 7h 07m by plane in normal conditions.

  • When did momondo last update prices for flights from Buffalo Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Buffalo Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from Buffalo Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Buffalo Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The required travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Buffalo to Santa Ana?

Best airlines flying from Buffalo to Santa Ana

Compare and see reviews for airlines that fly from Buffalo to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $379Free CancellationRating
7.2
11,352 reviews
Search American Airlines flights
SouthwestPriceFrom $392Free CancellationRating
8.0
4,299 reviews
Search Southwest flights
United AirlinesPriceFrom $446Free CancellationRating
7.4
9,348 reviews
Search United Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to Santa Ana?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Buffalo to Santa Ana. momondo saves you time and could save you money on your trip.

Can I find flights from Buffalo to Santa Ana with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Buffalo to Santa Ana flights to just show those with flexible booking policies.

How can momondo help me find flights from Buffalo to Santa Ana?

Once you have performed a search for Buffalo to Santa Ana flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Buffalo to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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