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Cheap flights from Buffalo to San Diego from $125

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to San Diego departing on 6/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:25 am - 10:23 am
BUF
-
SAN
6h 58m
1 stop
Delta Logo
2:30 pm - 11:59 pm
SAN
-
BUF
6h 29m
1 stop
$349Delta
Thu, May 28 - Wed, Jun 3
Southwest Logo
9:40 am - 6:10 pm
BUF
-
SAN
11h 30m
2 stops
Southwest Logo
6:40 am - 6:20 pm
SAN
-
BUF
8h 40m
1 stop
$354Southwest
Mon, Aug 31 - Sun, Sep 6
Southwest Logo
6:50 am - 1:10 pm
BUF
-
SAN
9h 20m
2 stops
Southwest Logo
9:30 pm - 11:10 am
SAN
-
BUF
10h 40m
2 stops
$359Southwest
Mon, Aug 31 - Sun, Sep 6
Southwest Logo
1:10 pm - 6:55 pm
BUF
-
SAN
8h 45m
1 stop
Southwest Logo
5:10 pm - 10:25 am
SAN
-
BUF
14h 15m
2 stops
$360Southwest
Wed, Jun 3 - Mon, Jun 8
Southwest Logo
4:00 pm - 11:05 pm
BUF
-
SAN
10h 05m
2 stops
Southwest Logo
5:10 pm - 10:25 am
SAN
-
BUF
14h 15m
2 stops
$365Southwest
Mon, Jun 1 - Mon, Jun 8
American Airlines Logo
12:47 pm - 8:53 pm
BUF
-
SAN
11h 06m
1 stop
American Airlines Logo
10:59 am - 10:35 pm
SAN
-
BUF
8h 36m
1 stop
$369American Airlines
Wed, Jun 17 - Sat, Jun 20
Southwest Logo
12:40 pm - 7:00 pm
BUF
-
SAN
9h 20m
1 stop
Southwest Logo
7:40 pm - 7:50 am
SAN
-
BUF
9h 10m
2 stops
$379Southwest
Thu, May 28 - Tue, Jun 2
Southwest Logo
2:25 pm - 9:55 pm
BUF
-
SAN
10h 30m
2 stops
Southwest Logo
8:15 pm - 7:55 am
SAN
-
BUF
8h 40m
2 stops
$380Southwest
Tue, Oct 13 - Thu, Oct 29
American Airlines Logo
12:51 pm - 8:53 pm
BUF
-
SAN
11h 02m
1 stop
American Airlines Logo
10:05 am - 9:52 pm
SAN
-
BUF
8h 47m
1 stop
$381American Airlines
Tue, May 26 - Thu, Jun 4
Delta Logo
10:32 am - 8:35 pm
BUF
-
SAN
13h 03m
1 stop
Delta Logo
10:00 pm - 9:44 am
SAN
-
BUF
8h 44m
1 stop
$386Delta
Wed, May 27 - Mon, Jun 1

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Delta flights from Buffalo to San Diego

Our best Delta deals on Buffalo to San Diego flight tickets
Delta
May 28
BUF6:25 amBuffalo
6h 58m
1 stop
SAN10:23 amSan Diego
Jun 2
SAN2:30 pmSan Diego
6h 29m
1 stop
BUF11:59 pmBuffalo
$349
Delta
May 27
BUF6:15 amBuffalo
8h 01m
1 stop
SAN11:16 amSan Diego
Jun 2
SAN2:30 pmSan Diego
6h 29m
1 stop
BUF11:59 pmBuffalo
$374
Delta
May 27
BUF7:00 amBuffalo
16h 35m
1 stop
SAN8:35 pmSan Diego
Jun 3
SAN2:30 pmSan Diego
6h 29m
1 stop
BUF11:59 pmBuffalo
$386

Southwest flights from Buffalo to San Diego

Our best Southwest deals on Buffalo to San Diego flight tickets
Southwest
Aug 31
BUF3:55 pmBuffalo
9h 50m
1 stop
SAN10:45 pmSan Diego
Sep 6
SAN9:30 pmSan Diego
10h 40m
2 stops
BUF11:10 amBuffalo
$354
Southwest
Aug 31
BUF3:55 pmBuffalo
9h 05m
2 stops
SAN10:00 pmSan Diego
Sep 6
SAN9:30 pmSan Diego
10h 40m
2 stops
BUF11:10 amBuffalo
$359
Southwest
Jun 3
BUF1:10 pmBuffalo
8h 45m
1 stop
SAN6:55 pmSan Diego
Jun 8
SAN5:10 pmSan Diego
14h 15m
2 stops
BUF10:25 amBuffalo
$360

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Buffalo to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 5/28

6:25 am-10:23 am

1 stop6h 58m

San Diego

Wed 6/3

2:30 pm-11:59 pm

1 stop6h 29m

$349

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Mon 8/31

9:40 am-6:10 pm

2 stops11h 30m

San Diego

Sun 9/6

6:40 am-6:20 pm

1 stop8h 40m

$354

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Mon 8/31

6:50 am-1:10 pm

2 stops9h 20m

San Diego

Sun 9/6

9:30 pm-11:10 am

2 stops10h 40m

$359

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 6/3

1:10 pm-6:55 pm

1 stop8h 45m

San Diego

Mon 6/8

5:10 pm-10:25 am

2 stops14h 15m

$360

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Mon 6/1

4:00 pm-11:05 pm

2 stops10h 05m

San Diego

Mon 6/8

5:10 pm-10:25 am

2 stops14h 15m

$365

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 6/17

12:47 pm-8:53 pm

1 stop11h 06m

San Diego

Sat 6/20

10:59 am-10:35 pm

1 stop8h 36m

$369

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 5/28

12:40 pm-7:00 pm

1 stop9h 20m

San Diego

Tue 6/2

7:40 pm-7:50 am

2 stops9h 10m

$379

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 10/13

2:25 pm-9:55 pm

2 stops10h 30m

San Diego

Thu 10/29

8:15 pm-7:55 am

2 stops8h 40m

$380

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 5/26

12:51 pm-8:53 pm

1 stop11h 02m

San Diego

Thu 6/4

10:05 am-9:52 pm

1 stop8h 47m

$381

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 5/27

10:32 am-8:35 pm

1 stop13h 03m

San Diego

Mon 6/1

10:00 pm-9:44 am

1 stop8h 44m

$386

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Buffalo to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Buffalo and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Buffalo during the month November is also very affordable. Most momondo users find prices during this month for around $368.

How far in advance should I book a flight from Buffalo to San Diego?

You are more likely to see cheaper flights to San Diego from Buffalo when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $396 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Buffalo for as low as $251 on momondo.

Can stopping save me money on Buffalo to San Diego flights?

You could potentially save up to 23% on your flight if you consider stops on a Buffalo to San Diego flight.

How have Buffalo to San Diego flight prices changed over time?

As of May 2026, prices for Buffalo to San Diego flights are approximately 17% more expensive when compared to flights at the same time last year.

When to book flights from Buffalo to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to San Diego (BUF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to San Diego

Fastest flight time

6h 50m

Direct flights

Sun

Airports in San Diego

1 airport
The fastest flight from Buffalo to San Diego takes 6h 50m
Direct flights go from Buffalo to San Diego on Sunday. There are no airlines offering direct flights.
There is 1 airport in San Diego. From Buffalo there are direct flights to San Diego (SAN).
Search flight deals

Frequently asked questions about flying from Buffalo to San Diego

  • How far is Buffalo to San Diego by plane?

    There are 2181.7 mi between Buffalo and San Diego. Typically, this will take 6h 50m by plane in normal conditions.

  • When did momondo last update prices for flights from Buffalo Airport to San Diego Airport?

    Prices for flights from Buffalo Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Buffalo Airport to San Diego Airport?

  • How old do you have to be to fly from Buffalo Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Buffalo to San Diego?

  • What is the most popular airline from Buffalo to San Diego?

Best airlines flying from Buffalo to San Diego

Compare and see reviews for airlines that fly from Buffalo to San Diego with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $172Free CancellationRating
7.1
2,978 reviews
Search JetBlue flights
DeltaPriceFrom $222Free CancellationRating
7.9
8,458 reviews
Search Delta flights
American AirlinesPriceFrom $245Free CancellationRating
7.1
11,668 reviews
Search American Airlines flights
SouthwestPriceFrom $267Free CancellationRating
7.9
4,305 reviews
Search Southwest flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
9,684 reviews
Search United Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
La Mesa
Imperial Beach
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Buffalo.

Can I find flights from Buffalo to San Diego with flexible booking policies on momondo?

Flights from Buffalo to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to San Diego?

momondo helps you find the best flight between Buffalo and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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