Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Buffalo to San Diego from $108

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to San Diego departing on 12/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
5:20 am - 12:20 pmBUF  Buffalo-SAN San Diego
10h 00m1 stop Tampa
Southwest Logo
6:45 am - 5:00 pmSAN  San Diego-BUF Buffalo
7h 15m1 stop Baltimore/Washington
$216Southwest
Thu, Dec 17 - Thu, Jan 7
Southwest Logo
7:00 pm - 11:15 pmBUF  Buffalo-SAN San Diego
7h 15m1 stop Chicago Midway
Southwest Logo
6:30 am - 6:50 pmSAN  San Diego-BUF Buffalo
9h 20m1 stop Chicago Midway
$216Southwest
Tue, Oct 20 - Sat, Oct 24
American Airlines Logo
5:50 pm - 11:33 pmBUF  Buffalo-SAN San Diego
8h 43m1 stop Chicago O'Hare Intl
American Airlines Logo
9:30 pm - 10:18 amSAN  San Diego-BUF Buffalo
9h 48m1 stop Philadelphia
$217American Airlines
Tue, Oct 6 - Sat, Oct 10
American Airlines Logo
6:56 pm - 11:25 pmBUF  Buffalo-SAN San Diego
7h 29m1 stop Chicago O'Hare Intl
American Airlines Logo
10:46 pm - 11:39 amSAN  San Diego-BUF Buffalo
9h 53m1 stop Chicago O'Hare Intl
$217American Airlines
Tue, Sep 22 - Tue, Sep 29
United Airlines Logo
10:33 am - 2:57 pmBUF  Buffalo-SAN San Diego
7h 24m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
9:45 pm - 9:52 amSAN  San Diego-BUF Buffalo
9h 07m2 stops Washington, D.C. Dulles Intl Newark
$276United Airlines
Fri, Sep 11 - Sat, Sep 19
United Airlines Logo
7:00 am - 11:25 amBUF  Buffalo-SAN San Diego
7h 25m1 stop Chicago O'Hare Intl
United Airlines Logo
9:45 pm - 9:52 amSAN  San Diego-BUF Buffalo
9h 07m2 stops Washington, D.C. Dulles Intl Newark
$276United Airlines
Tue, Sep 15 - Sat, Sep 19
Delta Logo
3:58 pm - 9:19 pmBUF  Buffalo-SAN San Diego
8h 21m1 stop Atlanta Hartsfield-Jackson
Delta Logo
9:59 pm - 10:26 amSAN  San Diego-BUF Buffalo
9h 27m1 stop New York John F Kennedy Intl
$297Delta
Wed, Sep 23 - Mon, Sep 28
Delta Logo
7:52 pm - 11:35 pmBUF  Buffalo-SAN San Diego
6h 43m1 stop Minneapolis St Paul
Delta Logo
10:20 pm - 8:24 amSAN  San Diego-BUF Buffalo
7h 04m1 stop Detroit Metropolitan Wayne County
$297Delta
Mon, Sep 7 - Fri, Sep 18
JetBlue Logo
6:00 am - 12:06 pmBUF  Buffalo-SAN San Diego
9h 06m1 stop Boston Logan Intl
JetBlue Logo
8:20 pm - 10:09 amSAN  San Diego-BUF Buffalo
10h 49m1 stop Boston Logan Intl
$424JetBlue
Sun, Sep 6 - Wed, Sep 16
JetBlue Logo
12:19 pm - 8:01 pmBUF  Buffalo-SAN San Diego
10h 42m1 stop New York John F Kennedy Intl
JetBlue Logo
8:20 pm - 10:09 amSAN  San Diego-BUF Buffalo
10h 49m1 stop Boston Logan Intl
$428JetBlue
Wed, Sep 9 - Wed, Sep 16

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Southwest flights from Buffalo to San Diego

Our best Southwest deals on Buffalo to San Diego flight tickets
Southwest
Oct 22
BUF7:35 pmBuffalo
7h 10m
1 stop
SAN11:45 pmSan Diego
Oct 26
SAN10:40 pmSan Diego
8h 45m
1 stop
BUF10:25 amBuffalo
$216
Southwest
Sep 26
BUF4:20 pmBuffalo
7h 05m
1 stop
SAN8:25 pmSan Diego
Oct 1
SAN5:05 pmSan Diego
11h 45m
1 stop
BUF7:50 amBuffalo
$222
Southwest
Sep 26
BUF4:20 pmBuffalo
9h 40m
2 stops
SAN11:00 pmSan Diego
Oct 1
SAN5:05 pmSan Diego
11h 45m
1 stop
BUF7:50 amBuffalo
$227

American Airlines flights from Buffalo to San Diego

Our best American Airlines deals on Buffalo to San Diego flight tickets
American Airlines
Sep 22
BUF6:56 pmBuffalo
7h 29m
1 stop
SAN11:25 pmSan Diego
Sep 29
SAN10:46 pmSan Diego
9h 53m
1 stop
BUF11:39 amBuffalo
$217
American Airlines
Sep 18
BUF4:47 pmBuffalo
8h 01m
1 stop
SAN9:48 pmSan Diego
Sep 22
SAN9:50 amSan Diego
10h 09m
1 stop
BUF10:59 pmBuffalo
$244
American Airlines
Dec 8
BUF8:00 amBuffalo
7h 39m
1 stop
SAN12:39 pmSan Diego
Dec 14
SAN10:40 pmSan Diego
9h 08m
1 stop
BUF10:48 amBuffalo
$271

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 17, 2026.
Use the filters below to find and compare flights from Buffalo to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Thu 12/17

5:20 am-12:20 pm

1 stop10h 00m

San Diego

Thu 1/7

6:45 am-5:00 pm

1 stop7h 15m

$216

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Tue 10/20

7:00 pm-11:15 pm

1 stop7h 15m

San Diego

Sat 10/24

6:30 am-6:50 pm

1 stop9h 20m

$216

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Tue 10/6

5:50 pm-11:33 pm

1 stop8h 43m

San Diego

Sat 10/10

9:30 pm-10:18 am

1 stop9h 48m

$217

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Tue 9/22

6:56 pm-11:25 pm

1 stop7h 29m

San Diego

Tue 9/29

10:46 pm-11:39 am

1 stop9h 53m

$217

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Fri 9/11

10:33 am-2:57 pm

1 stop7h 24m

San Diego

Sat 9/19

9:45 pm-9:52 am

2 stops9h 07m

$276

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Tue 9/15

7:00 am-11:25 am

1 stop7h 25m

San Diego

Sat 9/19

9:45 pm-9:52 am

2 stops9h 07m

$276

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Wed 9/23

3:58 pm-9:19 pm

1 stop8h 21m

San Diego

Mon 9/28

9:59 pm-10:26 am

1 stop9h 27m

$297
Quickest round-trip

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Mon 9/7

7:52 pm-11:35 pm

1 stop6h 43m

San Diego

Fri 9/18

10:20 pm-8:24 am

1 stop7h 04m

$297

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Sun 9/6

6:00 am-12:06 pm

1 stop9h 06m

San Diego

Wed 9/16

8:20 pm-10:09 am

1 stop10h 49m

$424

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Wed 9/9

12:19 pm-8:01 pm

1 stop10h 42m

San Diego

Wed 9/16

8:20 pm-10:09 am

1 stop10h 49m

$428

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Diego from

How to get the cheapest flight ticket from Buffalo to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Buffalo and San Diego?

Prices are currently low for flights on this route.

Typical prices usually range from $348 to $456.
The lowest price recently found on this route was $216.

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Buffalo during the month April is also very affordable. Most momondo users find prices during this month for around $370.

What is the cheapest Buffalo to San Diego flight route?

Fly from Buffalo to San Diego for the best Buffalo - San Diego flight prices

How far in advance should I book a flight from Buffalo to San Diego?

You are more likely to see cheaper flights to San Diego from Buffalo when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $406 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Buffalo for as low as $312 on momondo.

What cabin class options are available on Buffalo to San Diego flights?

There is only 1 cabin class available to choose from on Buffalo to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Buffalo to San Diego flights?

You could potentially save up to 25% on your flight if you consider stops on a Buffalo to San Diego flight.

How have Buffalo to San Diego flight prices changed over time?

As of August 2026, prices for Buffalo to San Diego flights are approximately 21% cheaper when compared to flights at the same time last year.

When to book flights from Buffalo to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to San Diego (BUF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to San Diego

Best Price Found

$108

Fastest flight time

6h 30m

Direct flights

None
The best one-way flight to San Diego from Buffalo in the past 72 hours is $108. The best round-trip flight deal from Buffalo to San Diego found on momondo in the last 72 hours is $216.
The fastest flight from Buffalo to San Diego takes 6h 30m
There are no direct flights from Buffalo to San Diego. There are no popular flight routes from Buffalo to San Diego.
Search flight deals

Frequently asked questions about flying from Buffalo to San Diego

  • How far is Buffalo to San Diego by plane?

    There are 2181.7 mi between Buffalo and San Diego. Typically, this will take 6h 30m by plane in normal conditions.

  • When did momondo last update prices for flights from Buffalo Airport to San Diego Airport?

    Prices for flights from Buffalo Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Buffalo Airport to San Diego Airport?

  • How old do you have to be to fly from Buffalo Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Buffalo to San Diego?

  • What is the most popular airline from Buffalo to San Diego?

Best airlines flying from Buffalo to San Diego

Compare and see reviews for airlines that fly from Buffalo to San Diego with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $172Free CancellationRating
7.1
3,032 reviews
Search JetBlue flights
DeltaPriceFrom $222Free CancellationRating
7.8
8,503 reviews
Search Delta flights
American AirlinesPriceFrom $260Free CancellationRating
7.1
11,945 reviews
Search American Airlines flights
SouthwestPriceFrom $279Free CancellationRating
8.0
4,218 reviews
Search Southwest flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
10,106 reviews
Search United Airlines flights

  • Southwest Flights From Buffalo to San Diego

    Southwest flight deals from Buffalo to San Diego start from $279 round-trip. Over the 1 Southwest flight for this route in a normal week, average airfare is usually $428 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
National City
Julian
La Mesa
Poway
San Ysidro
Imperial Beach
Santee
Borrego Springs
Lemon Grove
Alpine

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Buffalo.

Can I find flights from Buffalo to San Diego with flexible booking policies on momondo?

Flights from Buffalo to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to San Diego?

momondo helps you find the best flight between Buffalo and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 9/16
Wed 9/23
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States