Which layover airport has the shortest connection time from Buffalo to San Diego?

Detroit (DTW) has the shortest average layover time for this route: 1h 06m.

What is the cheapest airline that flies from Buffalo to San Diego?

Frontier, Delta, and American Airlines are the most popular carriers operating from Buffalo to San Diego

Which layover airport has the shortest travel time from Buffalo to San Diego?

Flights connecting via Detroit (DTW) have the shortest average one-way travel time: 6h 58m.

Which airport is the most popular layover for flights between Buffalo and San Diego?

Detroit (DTW) was the most common stop: 80% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to San Diego?

Southwest, United Airlines and American Airlines are the top three most popular airlines that fly to San Diego from Buffalo according to our data. Southwest is the first choice among our users, with 30% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 5 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

Which layover airport offers the lowest fares from Buffalo to San Diego?

Flights via Detroit (DTW) offer the lowest average round-trip price of $391.

When did momondo last update prices for flights from Buffalo Airport to San Diego Airport?

Prices for flights from Buffalo Airport to San Diego Airport are updated daily.

How many operators does momondo search for flights from Buffalo Airport to San Diego Airport?

There are 5 operators available for flights from Buffalo Airport to San Diego Airport as of August 2026.

How old do you have to be to fly from Buffalo Airport to San Diego Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to San Diego Airport.

What documentation or ID do you need to fly to San Diego Airport?

The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$141 Cheap Flights from Buffalo to San Diego in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to San Diego

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

12:56 pm - 6:22 pmBUF Buffalo-SAN San Diego

8h 26m1 stop Charlotte Douglas

12:08 pm - 10:59 pmSAN San Diego-BUF Buffalo

7h 51m1 stop Dallas/Fort Worth

$325American Airlines

Tue, Sep 15 - Tue, Sep 22

6:15 am - 10:20 amBUF Buffalo-SAN San Diego

7h 05m1 stop Detroit Metropolitan Wayne County

10:25 pm - 11:16 amSAN San Diego-BUF Buffalo

9h 51m1 stop Atlanta Hartsfield-Jackson

$326Delta

Wed, Oct 28 - Sun, Nov 1

6:56 pm - 11:25 pmBUF Buffalo-SAN San Diego

7h 29m1 stop Chicago O'Hare Intl

6:15 am - 5:18 pmSAN San Diego-BUF Buffalo

8h 03m1 stop Chicago O'Hare Intl

$326American Airlines

Thu, Sep 17 - Sun, Sep 20

6:00 am - 11:13 amBUF Buffalo-SAN San Diego

8h 13m1 stop Atlanta Hartsfield-Jackson

11:31 am - 10:38 pmSAN San Diego-BUF Buffalo

8h 07m1 stop Detroit Metropolitan Wayne County

$326Delta

Fri, Oct 23 - Fri, Nov 6

2:00 pm - 6:15 pmBUF Buffalo-SAN San Diego

7h 15m1 stop Chicago Midway

9:45 am - 10:45 pmSAN San Diego-BUF Buffalo

10h 00m1 stop Tampa

$327Southwest

Fri, Dec 4 - Tue, Dec 8

7:00 pm - 11:15 pmBUF Buffalo-SAN San Diego

7h 15m1 stop Chicago Midway

9:50 pm - 8:25 amSAN San Diego-BUF Buffalo

7h 35m1 stop Baltimore/Washington

$327Southwest

Wed, Oct 21 - Tue, Oct 27

5:45 pm - 10:41 pmBUF Buffalo-SAN San Diego

7h 56m1 stop Chicago O'Hare Intl

6:40 am - 4:43 pmSAN San Diego-BUF Buffalo

7h 03m1 stop Chicago O'Hare Intl

$327United Airlines

Fri, Sep 25 - Tue, Sep 29

7:00 am - 11:22 amBUF Buffalo-SAN San Diego

7h 22m1 stop Chicago O'Hare Intl

12:45 pm - 10:45 pmSAN San Diego-BUF Buffalo

7h 00m1 stop Denver Intl

$327United Airlines

Thu, Jan 7 - Sun, Jan 10

12:10 pm - 8:01 pmBUF Buffalo-SAN San Diego

10h 51m1 stop New York John F Kennedy Intl

9:30 pm - 8:27 amSAN San Diego-BUF Buffalo

7h 57m1 stop New York John F Kennedy Intl

$381JetBlue

Sat, Oct 24 - Tue, Oct 27

2:23 pm - 8:27 pmBUF Buffalo-SAN San Diego

9h 04m1 stop Boston Logan Intl

9:44 pm - 10:09 amSAN San Diego-BUF Buffalo

9h 25m1 stop Boston Logan Intl

$385JetBlue

Sat, Oct 3 - Sat, Oct 3

Cheap last minute flights

Enter your travel dates to find the best prices.

5:13 pm - 11:00 pmBUF Buffalo-SAN San Diego

8h 47m1 stop Atlanta Hartsfield-Jackson

6:29 am - 6:23 pmSAN San Diego-BUF Buffalo

8h 54m1 stop Minneapolis St Paul

$636Delta

Mon, Aug 31 - Sun, Sep 6

12:16 pm - 5:05 pmBUF Buffalo-SAN San Diego

7h 49m1 stop Atlanta Hartsfield-Jackson

6:29 am - 6:23 pmSAN San Diego-BUF Buffalo

8h 54m1 stop Minneapolis St Paul

$636Delta

Mon, Aug 31 - Sun, Sep 6

10:30 am - 2:57 pmBUF Buffalo-SAN San Diego

7h 27m1 stop Washington, D.C. Dulles Intl

10:40 pm - 9:28 amSAN San Diego-BUF Buffalo

7h 48m1 stop Chicago O'Hare Intl

$691United Airlines

Mon, Aug 31 - Sun, Sep 6

10:30 am - 3:02 pmBUF Buffalo-SAN San Diego

7h 32m1 stop Chicago O'Hare Intl

6:20 am - 11:44 pmSAN San Diego-BUF Buffalo

14h 24m2 stops Los Angeles Washington, D.C. Dulles Intl

$696United Airlines

Mon, Aug 31 - Sun, Sep 6

6:55 am - 3:54 pmBUF Buffalo-SAN San Diego

11h 59m2 stops Chicago O'Hare Intl San Francisco

10:40 pm - 9:28 amSAN San Diego-BUF Buffalo

7h 48m1 stop Chicago O'Hare Intl

$696United Airlines

Mon, Aug 31 - Sun, Sep 6

5:13 pm - 11:00 pmBUF Buffalo-SAN San Diego

8h 47m1 stop Atlanta Hartsfield-Jackson

11:30 am - 11:09 pmSAN San Diego-BUF Buffalo

8h 39m1 stop Detroit Metropolitan Wayne County

$738Delta

Mon, Aug 31 - Sun, Sep 6

10:30 am - 9:22 pmBUF Buffalo-SAN San Diego

13h 52m1 stop Chicago O'Hare Intl

7:24 am - 12:02 amSAN San Diego-BUF Buffalo

13h 38m1 stop Chicago O'Hare Intl

$877American Airlines

Mon, Aug 31 - Wed, Sep 2

10:30 am - 7:19 pmBUF Buffalo-SAN San Diego

11h 49m1 stop Chicago O'Hare Intl

7:24 am - 12:02 amSAN San Diego-BUF Buffalo

13h 38m1 stop Chicago O'Hare Intl

$939American Airlines

Mon, Aug 31 - Thu, Sep 3

8:35 am - 12:25 pmBUF Buffalo-SAN San Diego

6h 50m1 stop Chicago Midway

8:35 am - 8:35 pmSAN San Diego-BUF Buffalo

9h 00m2 stops Phoenix Sky Harbor Intl Chicago Midway

$950Southwest

Mon, Aug 31 - Wed, Sep 2

5:40 am - 12:25 pmBUF Buffalo-SAN San Diego

9h 45m2 stops Baltimore/Washington Chicago Midway

8:35 am - 8:35 pmSAN San Diego-BUF Buffalo

9h 00m2 stops Phoenix Sky Harbor Intl Chicago Midway

$955Southwest

Mon, Aug 31 - Wed, Sep 2

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United Airlines flights from Buffalo to San Diego

Our best United Airlines deals on Buffalo to San Diego flight tickets

United Airlines

Sep 23

BUF1:56 pmBuffalo

9h 06m

2 stops

SAN8:02 pmSan Diego

Sep 28

SAN10:30 pmSan Diego

7h 59m

1 stop

BUF9:29 amBuffalo

$332

United Airlines

Oct 7

BUF5:45 pmBuffalo

7h 56m

1 stop

SAN10:41 pmSan Diego

Oct 12

SAN10:30 pmSan Diego

7h 59m

1 stop

BUF9:29 amBuffalo

$365

United Airlines

Oct 7

BUF1:48 pmBuffalo

9h 20m

2 stops

SAN8:08 pmSan Diego

Oct 12

SAN10:30 pmSan Diego

7h 59m

1 stop

BUF9:29 amBuffalo

$370

Southwest flights from Buffalo to San Diego

Our best Southwest deals on Buffalo to San Diego flight tickets

Southwest

Oct 30

BUF4:50 pmBuffalo

9h 25m

2 stops

SAN11:15 pmSan Diego

Nov 2

SAN7:50 pmSan Diego

9h 35m

2 stops

BUF8:25 amBuffalo

$337

Southwest

Oct 8

BUF2:50 pmBuffalo

12h 20m

1 stop

SAN12:10 amSan Diego

Oct 15

SAN10:40 pmSan Diego

8h 45m

1 stop

BUF10:25 amBuffalo

$354

Southwest

Nov 2

BUF4:00 pmBuffalo

9h 15m

2 stops

SAN10:15 pmSan Diego

Nov 6

SAN7:50 pmSan Diego

9h 35m

2 stops

BUF8:25 amBuffalo

$359

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Tue 9/15

12:56 pm-6:22 pm

1 stop8h 26m

San Diego

Tue 9/22

12:08 pm-10:59 pm

1 stop7h 51m

$325

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Wed 10/28

6:15 am-10:20 am

1 stop7h 05m

San Diego

Sun 11/1

10:25 pm-11:16 am

1 stop9h 51m

$326

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Thu 9/17

6:56 pm-11:25 pm

1 stop7h 29m

San Diego

Sun 9/20

6:15 am-5:18 pm

1 stop8h 03m

$326

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Fri 10/23

6:00 am-11:13 am

1 stop8h 13m

San Diego

Fri 11/6

11:31 am-10:38 pm

1 stop8h 07m

$326

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Fri 12/4

2:00 pm-6:15 pm

1 stop7h 15m

San Diego

Tue 12/8

9:45 am-10:45 pm

1 stop10h 00m

$327

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Wed 10/21

7:00 pm-11:15 pm

1 stop7h 15m

San Diego

Tue 10/27

9:50 pm-8:25 am

1 stop7h 35m

$327

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Fri 9/25

5:45 pm-10:41 pm

1 stop7h 56m

San Diego

Tue 9/29

6:40 am-4:43 pm

1 stop7h 03m

$327

Quickest round-trip

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Thu 1/7

7:00 am-11:22 am

1 stop7h 22m

San Diego

Sun 1/10

12:45 pm-10:45 pm

1 stop7h 00m

$327

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Sat 10/24

12:10 pm-8:01 pm

1 stop10h 51m

San Diego

Tue 10/27

9:30 pm-8:27 am

1 stop7h 57m

$381

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Sat 10/3

2:23 pm-8:27 pm

1 stop9h 04m

San Diego

Sat 10/3

9:44 pm-10:09 am

1 stop9h 25m

$385

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Buffalo and San Diego?

Prices are currently low for flights on this route.

Typical prices usually range from $332 to $486.
The lowest price recently found on this route was $325.

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Buffalo during the month April is also very affordable. Most momondo users find prices during this month for around $370.

What is the cheapest Buffalo to San Diego flight route?

Fly from Buffalo to San Diego for the best Buffalo - San Diego flight prices

How far in advance should I book a flight from Buffalo to San Diego?

You are more likely to see cheaper flights to San Diego from Buffalo when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $404 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Buffalo for as low as $312 on momondo.

What cabin class options are available on Buffalo to San Diego flights?

There is only 1 cabin class available to choose from on Buffalo to San Diego flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Buffalo to San Diego flights?

You could potentially save up to 27% on your flight if you consider stops on a Buffalo to San Diego flight.

How have Buffalo to San Diego flight prices changed over time?

As of August 2026, prices for Buffalo to San Diego flights are approximately 21% cheaper when compared to flights at the same time last year.

When to book flights from Buffalo to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to San Diego according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Buffalo to San Diego (BUF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to San Diego

Best Price Found	$141
Fastest flight time	6h 57m
Direct flights	None

The best one-way flight to San Diego from Buffalo in the past 72 hours is $141. The best round-trip flight deal from Buffalo to San Diego found on momondo in the last 72 hours is $325.

The fastest flight from Buffalo to San Diego takes 6h 57m

There are no direct flights from Buffalo to San Diego. There are no popular flight routes from Buffalo to San Diego.

Search flight deals

Frequently asked questions about flying from Buffalo to San Diego

How far is Buffalo to San Diego by plane?
There are 2181.7 mi between Buffalo and San Diego. Typically, this will take 6h 57m by plane in normal conditions.
When did momondo last update prices for flights from Buffalo Airport to San Diego Airport?
Prices for flights from Buffalo Airport to San Diego Airport are updated daily.
How many operators does momondo search for flights from Buffalo Airport to San Diego Airport?
There are 5 operators available for flights from Buffalo Airport to San Diego Airport as of August 2026.
How old do you have to be to fly from Buffalo Airport to San Diego Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to San Diego Airport.
What documentation or ID do you need to fly to San Diego Airport?
The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Buffalo to San Diego?
Based on momondo bookings for flights between Buffalo and San Diego, the leading plane model is Boeing 737 MAX 8, making up 100.00% of the total bookings.
What is the most popular airline from Buffalo to San Diego?
momondo data reveals that the most frequently booked airline on the route from Buffalo to San Diego is Southwest, representing 27% of all bookings. The subsequent popular airlines are American Airlines at 25%, Delta at 24%, and United Airlines at 16%.

Best airlines flying from Buffalo to San Diego

Compare and see reviews for airlines that fly from Buffalo to San Diego with momondo

Airline	Rating	Free Cancellation	Price
JetBlue	PriceFrom $172	Free Cancellation	Rating 7.1 3,037 reviews	Search JetBlue flights
Delta	PriceFrom $222	Free Cancellation	Rating 7.8 8,529 reviews	Search Delta flights
American Airlines	PriceFrom $270	Free Cancellation	Rating 7.1 11,998 reviews	Search American Airlines flights
Southwest	PriceFrom $279	Free Cancellation	Rating 8.0 4,204 reviews	Search Southwest flights
United Airlines	PriceFrom $296	Free Cancellation	Rating 7.4 10,123 reviews	Search United Airlines flights

Chula Vista

Coronado

El Cajon

National City

Julian

La Mesa

Poway

San Ysidro

Imperial Beach

Santee

Borrego Springs

Lemon Grove

Alpine

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Buffalo.

Can I find flights from Buffalo to San Diego with flexible booking policies on momondo?

Flights from Buffalo to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to San Diego?

momondo helps you find the best flight between Buffalo and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Buffalo to San Diego from $141

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to San Diego departing on 10/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Buffalo to San Diego

Our best United Airlines deals on Buffalo to San Diego flight tickets

Southwest flights from Buffalo to San Diego

Our best Southwest deals on Buffalo to San Diego flight tickets

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See travel insights to San Diego from

How to get the cheapest flight ticket from Buffalo to San Diego

What is the typical price of a round-trip flight between Buffalo and San Diego?

What is the cheapest month to fly to San Diego?

What is the cheapest Buffalo to San Diego flight route?

How far in advance should I book a flight from Buffalo to San Diego?

What cabin class options are available on Buffalo to San Diego flights?

Can stopping save me money on Buffalo to San Diego flights?

How have Buffalo to San Diego flight prices changed over time?

What is the cheapest airline that flies from Buffalo to San Diego?

What airlines fly to San Diego?

Which airport is the most popular layover for flights between Buffalo and San Diego?

Which layover airport offers the lowest fares from Buffalo to San Diego?

Which layover airport has the shortest travel time from Buffalo to San Diego?

Which layover airport has the shortest connection time from Buffalo to San Diego?

When to book flights from Buffalo to San Diego

Cheap Buffalo to San Diego (BUF to SAN) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Buffalo to San Diego

Best airlines flying from Buffalo to San Diego

Compare and see reviews for airlines that fly from Buffalo to San Diego with momondo

Traveling to a place near San Diego?

Why use momondo?

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

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Find better results for your trip to the United States

Airports servicing California

Fly your favorite airline to San Diego

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to San Diego

List of cabin classes available on flights landing in San Diego. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

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