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Cheap flights from Buffalo to San Diego from $128

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to San Diego departing on 9/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Buffalo to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
12:10 pm - 8:01 pm
BUF
-
SAN
10h 51m
1 stop
JetBlue Logo
9:30 pm - 8:24 am
SAN
-
BUF
7h 54m
1 stop
$252JetBlue
Tue, Sep 22 - Tue, Sep 29
JetBlue Logo
1:31 pm - 7:30 pm
BUF
-
SAN
8h 59m
1 stop
JetBlue Logo
8:40 pm - 9:35 am
SAN
-
BUF
9h 55m
1 stop
$276JetBlue
Fri, Jul 3 - Thu, Jul 9
American Airlines Logo
12:09 pm - 5:29 pm
BUF
-
SAN
8h 20m
1 stop
American Airlines Logo
6:15 am - 5:16 pm
SAN
-
BUF
8h 01m
1 stop
$297American Airlines
Wed, Sep 16 - Tue, Sep 22
JetBlue Logo
9:15 am - 6:48 pm
BUF
-
SAN
12h 33m
1 stop
JetBlue Logo
8:20 pm - 11:14 am
SAN
-
BUF
11h 54m
1 stop
$300JetBlue
Wed, Sep 16 - Tue, Sep 22
JetBlue Logo
6:00 am - 11:56 am
BUF
-
SAN
8h 56m
1 stop
JetBlue Logo
8:40 pm - 9:34 am
SAN
-
BUF
9h 54m
1 stop
$301JetBlue
Tue, Aug 25 - Wed, Aug 26
JetBlue Logo
6:00 am - 11:56 am
BUF
-
SAN
8h 56m
1 stop
JetBlue Logo
8:20 pm - 11:14 am
SAN
-
BUF
11h 54m
1 stop
$303JetBlue
Tue, Sep 8 - Fri, Sep 11
Delta Logo
12:02 pm - 6:14 pm
BUF
-
SAN
9h 12m
1 stop
Delta Logo
10:17 pm - 8:15 am
SAN
-
BUF
6h 58m
1 stop
$314Delta
Tue, Aug 25 - Sat, Aug 29
JetBlue Logo
10:25 am - 7:27 pm
BUF
-
SAN
12h 02m
1 stop
JetBlue Logo
8:40 pm - 9:46 am
SAN
-
BUF
10h 06m
1 stop
$327JetBlue
Wed, Jul 8 - Sun, Jul 12
Delta Logo
7:52 pm - 11:35 pm
BUF
-
SAN
6h 43m
1 stop
Delta Logo
10:30 pm - 11:11 am
SAN
-
BUF
9h 41m
1 stop
$331Delta
Thu, Aug 27 - Mon, Aug 31
JetBlue Logo
10:25 am - 7:27 pm
BUF
-
SAN
12h 02m
1 stop
JetBlue Logo
8:40 pm - 9:35 am
SAN
-
BUF
9h 55m
1 stop
$337JetBlue
Thu, Jul 16 - Mon, Jul 20

American Airlines flights from Buffalo to San Diego

Our best American Airlines deals on Buffalo to San Diego flight tickets
American Airlines
Sep 22
BUF6:30 amBuffalo
9h 30m
1 stop
SAN1:00 pmSan Diego
Sep 29
SAN10:46 pmSan Diego
9h 53m
1 stop
BUF11:39 amBuffalo
$297
American Airlines
Aug 4
BUF6:32 amBuffalo
8h 55m
1 stop
SAN12:27 pmSan Diego
Aug 11
SAN10:45 pmSan Diego
7h 54m
1 stop
BUF9:39 amBuffalo
$344
American Airlines
Sep 22
BUF12:56 pmBuffalo
8h 26m
1 stop
SAN6:22 pmSan Diego
Sep 29
SAN9:46 amSan Diego
10h 13m
2 stops
BUF10:59 pmBuffalo
$345

Southwest flights from Buffalo to San Diego

Our best Southwest deals on Buffalo to San Diego flight tickets
Southwest
Aug 13
BUF3:55 pmBuffalo
9h 50m
1 stop
SAN10:45 pmSan Diego
Aug 16
SAN4:05 pmSan Diego
6h 25m
1 stop
BUF1:30 amBuffalo
$399
Southwest
Aug 13
BUF3:55 pmBuffalo
9h 00m
2 stops
SAN9:55 pmSan Diego
Aug 16
SAN4:05 pmSan Diego
6h 25m
1 stop
BUF1:30 amBuffalo
$405
Southwest
Jul 21
BUF8:30 amBuffalo
8h 30m
2 stops
SAN2:00 pmSan Diego
Jul 28
SAN9:55 pmSan Diego
11h 05m
1 stop
BUF12:00 pmBuffalo
$411

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 5, 2026.
Use the filters below to find and compare flights from Buffalo to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 9/22

12:10 pm-8:01 pm

1 stop10h 51m

San Diego

Tue 9/29

9:30 pm-8:24 am

1 stop7h 54m

$252

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Fri 7/3

1:31 pm-7:30 pm

1 stop8h 59m

San Diego

Thu 7/9

8:40 pm-9:35 am

1 stop9h 55m

$276

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 9/16

12:09 pm-5:29 pm

1 stop8h 20m

San Diego

Tue 9/22

6:15 am-5:16 pm

1 stop8h 01m

$297

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 9/16

9:15 am-6:48 pm

1 stop12h 33m

San Diego

Tue 9/22

8:20 pm-11:14 am

1 stop11h 54m

$300

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 8/25

6:00 am-11:56 am

1 stop8h 56m

San Diego

Wed 8/26

8:40 pm-9:34 am

1 stop9h 54m

$301

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 9/8

6:00 am-11:56 am

1 stop8h 56m

San Diego

Fri 9/11

8:20 pm-11:14 am

1 stop11h 54m

$303
Quickest round-trip

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 8/25

12:02 pm-6:14 pm

1 stop9h 12m

San Diego

Sat 8/29

10:17 pm-8:15 am

1 stop6h 58m

$314

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 7/8

10:25 am-7:27 pm

1 stop12h 02m

San Diego

Sun 7/12

8:40 pm-9:46 am

1 stop10h 06m

$327

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 8/27

7:52 pm-11:35 pm

1 stop6h 43m

San Diego

Mon 8/31

10:30 pm-11:11 am

1 stop9h 41m

$331

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 7/16

10:25 am-7:27 pm

1 stop12h 02m

San Diego

Mon 7/20

8:40 pm-9:35 am

1 stop9h 55m

$337

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Buffalo to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Buffalo and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Buffalo during the month April is also very affordable. Most momondo users find prices during this month for around $366.

How far in advance should I book a flight from Buffalo to San Diego?

You are more likely to see cheaper flights to San Diego from Buffalo when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $395 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Buffalo for as low as $334 on momondo.

Can stopping save me money on Buffalo to San Diego flights?

You could potentially save up to 36% on your flight if you consider stops on a Buffalo to San Diego flight.

How have Buffalo to San Diego flight prices changed over time?

As of June 2026, prices for Buffalo to San Diego flights are approximately 3% more expensive when compared to flights at the same time last year.

When to book flights from Buffalo to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to San Diego (BUF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to San Diego

Fastest flight time

6h 45m

Direct flights

None
The fastest flight from Buffalo to San Diego takes 6h 45m
There are no direct flights from Buffalo to San Diego. There are no popular flight routes from Buffalo to San Diego.
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Frequently asked questions about flying from Buffalo to San Diego

  • How far is Buffalo to San Diego by plane?

    There are 2181.7 mi between Buffalo and San Diego. Typically, this will take 6h 45m by plane in normal conditions.

  • When did momondo last update prices for flights from Buffalo Airport to San Diego Airport?

    Prices for flights from Buffalo Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Buffalo Airport to San Diego Airport?

  • How old do you have to be to fly from Buffalo Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Buffalo to San Diego?

  • What is the most popular airline from Buffalo to San Diego?

Best airlines flying from Buffalo to San Diego

Compare and see reviews for airlines that fly from Buffalo to San Diego with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $172Free CancellationRating
7.1
2,982 reviews
Search JetBlue flights
DeltaPriceFrom $222Free CancellationRating
7.8
8,396 reviews
Search Delta flights
American AirlinesPriceFrom $250Free CancellationRating
7.1
11,649 reviews
Search American Airlines flights
SouthwestPriceFrom $267Free CancellationRating
8.0
4,255 reviews
Search Southwest flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
9,778 reviews
Search United Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Chula Vista
Coronado
El Cajon
Julian
National City
Poway
San Ysidro
La Mesa
Borrego Springs
Lemon Grove
Imperial Beach
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Buffalo.

Can I find flights from Buffalo to San Diego with flexible booking policies on momondo?

Flights from Buffalo to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to San Diego?

momondo helps you find the best flight between Buffalo and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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