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Cheap flights from Buffalo to San Diego from $125

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to San Diego departing on 2/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Buffalo to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
8:00 am - 2:23 pm
BUF
-
SAN
9h 23m
1 stop
JetBlue Logo
9:10 pm - 9:35 am
SAN
-
BUF
9h 25m
1 stop
$269JetBlue
Thu, Feb 26 - Mon, Mar 2
Delta Logo
5:44 pm - 10:31 pm
BUF
-
SAN
7h 47m
1 stop
Delta Logo
10:00 pm - 11:05 am
SAN
-
BUF
10h 05m
1 stop
$297Delta
Mon, Feb 2 - Mon, Feb 16
American Airlines Logo
1:31 pm - 8:14 pm
BUF
-
SAN
9h 43m
2 stops
American Airlines Logo
1:12 pm - 11:38 pm
SAN
-
BUF
7h 26m
1 stop
$302American Airlines
Tue, Feb 24 - Tue, Mar 3
JetBlue Logo
8:00 am - 2:23 pm
BUF
-
SAN
9h 23m
1 stop
JetBlue Logo
9:10 pm - 9:35 am
SAN
-
BUF
9h 25m
1 stop
$303JetBlue
Thu, Feb 26 - Mon, Mar 2
Southwest Logo
9:00 am - 7:35 pm
BUF
-
SAN
13h 35m
2 stops
Southwest Logo
9:40 pm - 8:00 am
SAN
-
BUF
7h 20m
1 stop
$333Southwest
Wed, Jun 17 - Tue, Jun 23
Southwest Logo
11:00 am - 7:35 pm
BUF
-
SAN
11h 35m
2 stops
Southwest Logo
7:50 am - 7:55 pm
SAN
-
BUF
9h 05m
2 stops
$339Southwest
Wed, Jun 17 - Tue, Jun 23
Delta Logo
3:38 pm - 12:05 am
BUF
-
SAN
11h 27m
1 stop
Delta Logo
10:00 pm - 9:53 am
SAN
-
BUF
8h 53m
1 stop
$356Delta
Fri, Jan 30 - Sun, Feb 1
American Airlines Logo
1:31 pm - 9:07 pm
BUF
-
SAN
10h 36m
1 stop
American Airlines Logo
9:41 pm - 10:58 am
SAN
-
BUF
10h 17m
1 stop
$357American Airlines
Thu, Feb 12 - Mon, Feb 23
United Airlines Logo
8:30 am - 5:28 pm
BUF
-
SAN
11h 58m
2 stops
United Airlines Logo
10:52 am - 8:29 pm
SAN
-
BUF
6h 37m
1 stop
$361United Airlines
Fri, Jan 30 - Mon, Feb 2
American Airlines Logo
4:01 pm - 10:58 pm
BUF
-
SAN
9h 57m
1 stop
American Airlines Logo
6:15 am - 6:13 pm
SAN
-
BUF
8h 58m
2 stops
$363American Airlines
Mon, Feb 2 - Thu, Feb 5

United Airlines flights from Buffalo to San Diego

Our best United Airlines deals on Buffalo to San Diego flight tickets
United Airlines
Feb 7
BUF8:30 amBuffalo
10h 06m
1 stop
SAN3:36 pmSan Diego
Feb 12
SAN11:05 amSan Diego
8h 56m
2 stops
BUF11:01 pmBuffalo
$302
United Airlines
Feb 7
BUF8:30 amBuffalo
9h 34m
2 stops
SAN3:04 pmSan Diego
Feb 12
SAN11:05 amSan Diego
8h 56m
2 stops
BUF11:01 pmBuffalo
$308
United Airlines
Jun 26
BUF7:00 amBuffalo
7h 22m
1 stop
SAN11:22 amSan Diego
Jul 24
SAN10:30 pmSan Diego
8h 19m
1 stop
BUF9:49 amBuffalo
$323

Delta flights from Buffalo to San Diego

Our best Delta deals on Buffalo to San Diego flight tickets
Delta
Feb 2
BUF3:38 pmBuffalo
11h 27m
1 stop
SAN12:05 amSan Diego
Feb 16
SAN10:00 pmSan Diego
10h 05m
1 stop
BUF11:05 amBuffalo
$297
Delta
Feb 11
BUF12:25 pmBuffalo
9h 36m
1 stop
SAN7:01 pmSan Diego
Feb 23
SAN10:00 pmSan Diego
10h 05m
1 stop
BUF11:05 amBuffalo
$317
Delta
Mar 18
BUF1:00 pmBuffalo
7h 51m
1 stop
SAN5:51 pmSan Diego
Mar 24
SAN10:25 pmSan Diego
9h 32m
1 stop
BUF10:57 amBuffalo
$348

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Buffalo to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 2/26

8:00 am-2:23 pm

1 stop9h 23m

San Diego

Mon 3/2

9:10 pm-9:35 am

1 stop9h 25m

$269

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Mon 2/2

5:44 pm-10:31 pm

1 stop7h 47m

San Diego

Mon 2/16

10:00 pm-11:05 am

1 stop10h 05m

$297

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 2/24

1:31 pm-8:14 pm

2 stops9h 43m

San Diego

Tue 3/3

1:12 pm-11:38 pm

1 stop7h 26m

$302

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 2/26

8:00 am-2:23 pm

1 stop9h 23m

San Diego

Mon 3/2

9:10 pm-9:35 am

1 stop9h 25m

$303

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 6/17

9:00 am-7:35 pm

2 stops13h 35m

San Diego

Tue 6/23

9:40 pm-8:00 am

1 stop7h 20m

$333

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 6/17

11:00 am-7:35 pm

2 stops11h 35m

San Diego

Tue 6/23

7:50 am-7:55 pm

2 stops9h 05m

$339

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Fri 1/30

3:38 pm-12:05 am

1 stop11h 27m

San Diego

Sun 2/1

10:00 pm-9:53 am

1 stop8h 53m

$356

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 2/12

1:31 pm-9:07 pm

1 stop10h 36m

San Diego

Mon 2/23

9:41 pm-10:58 am

1 stop10h 17m

$357

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Fri 1/30

8:30 am-5:28 pm

2 stops11h 58m

San Diego

Mon 2/2

10:52 am-8:29 pm

1 stop6h 37m

$361

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Mon 2/2

4:01 pm-10:58 pm

1 stop9h 57m

San Diego

Thu 2/5

6:15 am-6:13 pm

2 stops8h 58m

$363

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Buffalo to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Buffalo during the month September is also very affordable. Most momondo users find prices during this month for around $366.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Buffalo when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $411 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Buffalo for as low as $331 on momondo.

Can stopping save me money on Buffalo to San Diego flights?

You could potentially save up to 17% on your flight if you consider stops on a Buffalo to San Diego flight.

How have Buffalo to San Diego flight prices changed over time?

As of January 2026, prices for Buffalo to San Diego flights are approximately 22% cheaper when compared to flights at the same time last year.

When to book flights from Buffalo to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to San Diego (BUF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to San Diego

Fastest flight time

7h 22m

Direct flights

None
The fastest flight from Buffalo to San Diego takes 7h 22m
There are no direct flights from Buffalo to San Diego. There are no popular flight routes from Buffalo to San Diego.
Search flight deals

  • How far is Buffalo to San Diego by plane?

    There are 2181.7 mi between Buffalo and San Diego. Typically, this will take 7h 22m by plane in normal conditions.

  • When did momondo last update prices for flights from Buffalo Airport to San Diego Airport?

    Prices for flights from Buffalo Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Buffalo Airport to San Diego Airport?

  • How old do you have to be to fly from Buffalo Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Buffalo to San Diego?

  • What is the most popular airline from Buffalo to San Diego?

Best airlines flying from Buffalo to San Diego

Compare and see reviews for airlines that fly from Buffalo to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $99Free CancellationRating
5.7
3,056 reviews
Search Frontier flights
JetBluePriceFrom $183Free CancellationRating
7.2
2,884 reviews
Search JetBlue flights
SouthwestPriceFrom $230Free CancellationRating
8.0
4,256 reviews
Search Southwest flights
American AirlinesPriceFrom $256Free CancellationRating
7.2
11,114 reviews
Search American Airlines flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
9,149 reviews
Search United Airlines flights
DeltaPriceFrom $296Free CancellationRating
7.9
8,039 reviews
Search Delta flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
Borrego Springs
San Ysidro
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Buffalo.

Can I find flights from Buffalo to San Diego with flexible booking policies on momondo?

Flights from Buffalo to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to San Diego?

momondo helps you find the best flight between Buffalo and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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