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Cheap flights from Buffalo to San Diego from $126

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to San Diego departing on 2/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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JetBlue Logo
7:00 am - 2:10 pmBUF-SAN
10h 10m1 stop
JetBlue Logo
9:00 pm - 9:04 amSAN-BUF
9h 04m1 stop
$269JetBlue
Find Deal
Sun, Jan 18 - Thu, Jan 22
Multiple Airlines Logo
3:28 pm - 12:36 pmBUF-SAN
24h 08m1 stop
Multiple Airlines Logo
6:25 am - 4:00 pmSAN-BUF
30h 35m2 stops
$297Multiple Airlines
Find Deal
Wed, Nov 26 - Wed, Dec 3
JetBlue Logo
11:48 am - 7:19 pmBUF-SAN
10h 31m1 stop
JetBlue Logo
8:31 pm - 10:19 amSAN-BUF
10h 48m1 stop
$303JetBlue
Find Deal
Wed, Dec 10 - Wed, Dec 17
JetBlue Logo
7:00 am - 2:10 pmBUF-SAN
10h 10m1 stop
JetBlue Logo
9:00 pm - 9:04 amSAN-BUF
9h 04m1 stop
$307JetBlue
Find Deal
Fri, Jan 9 - Fri, Jan 16
JetBlue Logo
7:00 am - 2:10 pmBUF-SAN
10h 10m1 stop
JetBlue Logo
9:00 pm - 9:28 amSAN-BUF
9h 28m1 stop
$308JetBlue
Find Deal
Mon, Feb 2 - Mon, Feb 16
JetBlue Logo
7:00 am - 2:10 pmBUF-SAN
10h 10m1 stop
JetBlue Logo
9:00 pm - 9:04 amSAN-BUF
9h 04m1 stop
$315JetBlue
Find Deal
Fri, Jan 9 - Thu, Jan 15
JetBlue Logo
11:48 am - 7:21 pmBUF-SAN
10h 33m1 stop
JetBlue Logo
8:44 pm - 10:19 amSAN-BUF
10h 35m1 stop
$328JetBlue
Find Deal
Mon, Dec 15 - Wed, Dec 24
American Airlines Logo
4:01 pm - 10:58 pmBUF-SAN
9h 57m1 stop
American Airlines Logo
6:20 am - 7:16 pmSAN-BUF
9h 56m1 stop
$339American Airlines
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Mon, Jan 12 - Sat, Jan 17
JetBlue Logo
11:48 am - 7:21 pmBUF-SAN
10h 33m1 stop
JetBlue Logo
8:31 pm - 10:55 amSAN-BUF
11h 24m1 stop
$342JetBlue
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Tue, Dec 9 - Mon, Dec 15
American Airlines Logo
5:16 pm - 10:26 pmBUF-SAN
8h 10m1 stop
American Airlines Logo
10:09 am - 9:06 pmSAN-BUF
7h 57m2 stops
$344American Airlines
Find Deal
Mon, Jan 12 - Sat, Jan 17

JetBlue flights from Buffalo to San Diego

Our best JetBlue deals on Buffalo to San Diego flight tickets
JetBlue
Jan 18
BUF7:00 amBuffalo
10h 10m
1 stop
SAN2:10 pmSan Diego
Jan 22
SAN9:00 pmSan Diego
9h 04m
1 stop
BUF9:04 amBuffalo
$269
Find similar
JetBlue
Dec 10
BUF11:48 amBuffalo
10h 31m
1 stop
SAN7:19 pmSan Diego
Dec 17
SAN8:31 pmSan Diego
10h 48m
1 stop
BUF10:19 amBuffalo
$303
Find similar
JetBlue
Jan 9
BUF7:00 amBuffalo
10h 10m
1 stop
SAN2:10 pmSan Diego
Jan 16
SAN9:00 pmSan Diego
9h 04m
1 stop
BUF9:04 amBuffalo
$307
Find similar

Southwest flights from Buffalo to San Diego

Our best Southwest deals on Buffalo to San Diego flight tickets
Southwest
Jan 12
BUF3:45 pmBuffalo
9h 35m
2 stops
SAN10:20 pmSan Diego
Jan 17
SAN7:45 pmSan Diego
9h 20m
2 stops
BUF8:05 amBuffalo
$356
Find similar
Southwest
Jan 7
BUF9:25 amBuffalo
9h 30m
1 stop
SAN3:55 pmSan Diego
Jan 15
SAN9:45 pmSan Diego
7h 20m
1 stop
BUF8:05 amBuffalo
$363
Find similar
Southwest
Jan 7
BUF3:45 pmBuffalo
8h 15m
1 stop
SAN9:00 pmSan Diego
Jan 15
SAN10:30 amSan Diego
8h 05m
2 stops
BUF9:35 pmBuffalo
$368
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momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Buffalo to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Sun 1/18

7:00 am-2:10 pm

1 stop10h 10m

San Diego

Thu 1/22

9:00 pm-9:04 am

1 stop9h 04m

$269

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 11/26

3:28 pm-12:36 pm

1 stop24h 08m

San Diego

Wed 12/3

6:25 am-4:00 pm

2 stops30h 35m

$297

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 12/10

11:48 am-7:19 pm

1 stop10h 31m

San Diego

Wed 12/17

8:31 pm-10:19 am

1 stop10h 48m

$303

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Fri 1/9

7:00 am-2:10 pm

1 stop10h 10m

San Diego

Fri 1/16

9:00 pm-9:04 am

1 stop9h 04m

$307

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Mon 2/2

7:00 am-2:10 pm

1 stop10h 10m

San Diego

Mon 2/16

9:00 pm-9:28 am

1 stop9h 28m

$308

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Fri 1/9

7:00 am-2:10 pm

1 stop10h 10m

San Diego

Thu 1/15

9:00 pm-9:04 am

1 stop9h 04m

$315

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Mon 12/15

11:48 am-7:21 pm

1 stop10h 33m

San Diego

Wed 12/24

8:44 pm-10:19 am

1 stop10h 35m

$328

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Mon 1/12

4:01 pm-10:58 pm

1 stop9h 57m

San Diego

Sat 1/17

6:20 am-7:16 pm

1 stop9h 56m

$339

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 12/9

11:48 am-7:21 pm

1 stop10h 33m

San Diego

Mon 12/15

8:31 pm-10:55 am

1 stop11h 24m

$342

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Mon 1/12

5:16 pm-10:26 pm

1 stop8h 10m

San Diego

Sat 1/17

10:09 am-9:06 pm

2 stops7h 57m

$344

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Buffalo to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Buffalo during the month September is also very affordable. Most momondo users find prices during this month for around $373.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Buffalo to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $397. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $551. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $330. Flights in the morning are often more expensive with an average ticket price of $457.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Buffalo when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $431 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Buffalo for as low as $354 on momondo.

How have Buffalo to San Diego flight prices changed over time?

As of November 2025, prices for Buffalo to San Diego flights are approximately 2% cheaper when compared to flights at the same time last year.

When to book flights from Buffalo to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to San Diego (BUF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to San Diego

Direct flights

None
There are no direct flights from Buffalo to San Diego. There are no popular flight routes from Buffalo to San Diego.
Search flight deals

  • How far is Buffalo to San Diego by plane?

    There are 2181.7 mi between Buffalo and San Diego. Typically, this will take 7h 14m by plane in normal conditions.

  • When did momondo last update prices for flights from Buffalo Airport to San Diego Airport?

    Prices for flights from Buffalo Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Buffalo Airport to San Diego Airport?

  • How old do you have to be to fly from Buffalo Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Buffalo to San Diego?

  • What is the most popular airline from Buffalo to San Diego?

Best airlines flying from Buffalo to San Diego

Compare and see reviews for airlines that fly from Buffalo to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $99Free CancellationRating
5.8
3,104 reviews
Search Frontier flights
JetBluePriceFrom $256Free CancellationRating
7.2
2,902 reviews
Search JetBlue flights
American AirlinesPriceFrom $256Free CancellationRating
7.2
11,046 reviews
Search American Airlines flights
SouthwestPriceFrom $267Free CancellationRating
8.0
4,251 reviews
Search Southwest flights
DeltaPriceFrom $296Free CancellationRating
7.9
8,002 reviews
Search Delta flights
United AirlinesPriceFrom $331Free CancellationRating
7.4
9,028 reviews
Search United Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Imperial Beach
La Mesa
Poway
Borrego Springs
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Buffalo.

Can I find flights from Buffalo to San Diego with flexible booking policies on momondo?

Flights from Buffalo to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to San Diego?

momondo helps you find the best flight between Buffalo and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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