What is the cheapest airline that flies from Buffalo to San Diego?

Southwest, Delta, and United Airlines are the most popular carriers operating from Buffalo to San Diego

What airlines fly to San Diego?

United Airlines, Southwest and American Airlines are the top three most popular airlines that fly to San Diego from Buffalo according to our data. United Airlines is the first choice among our users, with 29% of people opting to fly with this airline when traveling to San Diego. Keep in mind that there are 6 different airlines that fly to San Diego on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Buffalo Airport to San Diego Airport?

Prices for flights from Buffalo Airport to San Diego Airport are updated daily.

How many operators does momondo search for flights from Buffalo Airport to San Diego Airport?

There are 5 operators available for flights from Buffalo Airport to San Diego Airport as of October 2026.

How old do you have to be to fly from Buffalo Airport to San Diego Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to San Diego Airport.

What documentation or ID do you need to fly to San Diego Airport?

The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$114 Cheap Flights from Buffalo to San Diego in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Buffalo to San Diego

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:30 am - 7:33 pmBUF Buffalo-SAN San Diego

11h 03m1 stop Boston Logan Intl

9:40 pm - 9:34 amSAN San Diego-BUF Buffalo

8h 54m1 stop New York John F Kennedy Intl

$226JetBlue

Thu, Dec 10 - Mon, Dec 14

11:30 am - 7:33 pmBUF Buffalo-SAN San Diego

11h 03m1 stop Boston Logan Intl

9:45 pm - 8:22 amSAN San Diego-BUF Buffalo

7h 37m1 stop New York John F Kennedy Intl

$226JetBlue

Thu, Dec 10 - Sat, Jan 9

5:00 pm - 11:10 pmBUF Buffalo-SAN San Diego

9h 10m1 stop Nashville Intl

9:55 pm - 8:05 amSAN San Diego-BUF Buffalo

7h 10m1 stop Baltimore/Washington

$227Southwest

Tue, Jan 5 - Tue, Jan 26

6:55 pm - 11:25 pmBUF Buffalo-SAN San Diego

7h 30m1 stop Chicago Midway

6:35 am - 6:10 pmSAN San Diego-BUF Buffalo

8h 35m1 stop Baltimore/Washington

$227Southwest

Thu, Dec 3 - Wed, Dec 9

12:50 pm - 8:48 pmBUF Buffalo-SAN San Diego

10h 58m1 stop Charlotte Douglas

11:43 am - 11:28 pmSAN San Diego-BUF Buffalo

8h 45m1 stop Chicago O'Hare Intl

$227American Airlines

Tue, Dec 8 - Wed, Jan 6

7:00 am - 2:23 pmBUF Buffalo-SAN San Diego

10h 23m1 stop Dallas/Fort Worth

10:14 am - 9:55 pmSAN San Diego-BUF Buffalo

8h 41m1 stop Chicago O'Hare Intl

$227American Airlines

Thu, Dec 10 - Tue, Dec 15

5:58 pm - 10:40 pmBUF Buffalo-SAN San Diego

7h 42m1 stop Chicago O'Hare Intl

9:45 pm - 10:08 amSAN San Diego-BUF Buffalo

9h 23m2 stops Washington, D.C. Dulles Intl Newark

$242United Airlines

Wed, Nov 11 - Mon, Nov 16

1:50 pm - 8:08 pmBUF Buffalo-SAN San Diego

9h 18m2 stops Chicago O'Hare Intl Los Angeles

7:00 am - 7:32 pmSAN San Diego-BUF Buffalo

9h 32m1 stop Newark

$242United Airlines

Sat, Jan 16 - Sat, Jan 23

6:41 pm - 11:38 pmBUF Buffalo-SAN San Diego

7h 57m1 stop Atlanta Hartsfield-Jackson

10:40 pm - 11:15 amSAN San Diego-BUF Buffalo

9h 35m1 stop Atlanta Hartsfield-Jackson

$297Delta

Mon, Dec 7 - Thu, Jan 7

6:35 am - 10:26 amBUF Buffalo-SAN San Diego

6h 51m1 stop Detroit Metropolitan Wayne County

8:00 am - 9:04 pmSAN San Diego-BUF Buffalo

10h 04m1 stop Atlanta Hartsfield-Jackson

$297Delta

Fri, Nov 20 - Thu, Nov 26

Cheap last minute flights

Enter your travel dates to find the best prices.

1:44 pm - 4:49 pmBUF Buffalo-SAN San Diego

30h 05m2 stops Atlanta Hartsfield-Jackson Las Vegas Harry Reid Intl

6:25 am - 12:59 pmSAN San Diego-BUF Buffalo

27h 34m2 stops Denver Intl Atlanta Hartsfield-Jackson

$973Frontier

Fri, Oct 23 - Sun, Oct 25

5:45 pm - 10:41 pmBUF Buffalo-SAN San Diego

7h 56m1 stop Chicago O'Hare Intl

10:30 pm - 9:42 amSAN San Diego-BUF Buffalo

8h 12m1 stop Chicago O'Hare Intl

$985United Airlines

Sat, Oct 24 - Tue, Oct 27

11:38 am - 7:56 pmBUF Buffalo-SAN San Diego

11h 18m1 stop New York John F Kennedy Intl

8:26 pm - 11:08 amSAN San Diego-BUF Buffalo

11h 42m1 stop Boston Logan Intl

$1,019JetBlue

Fri, Oct 23 - Mon, Oct 26

11:38 am - 7:56 pmBUF Buffalo-SAN San Diego

11h 18m1 stop New York John F Kennedy Intl

8:26 pm - 11:08 amSAN San Diego-BUF Buffalo

11h 42m1 stop Boston Logan Intl

$1,019JetBlue

Fri, Oct 23 - Sun, Oct 25

5:50 am - 11:08 amBUF Buffalo-SAN San Diego

8h 18m1 stop Charlotte Douglas

11:33 am - 11:59 pmSAN San Diego-BUF Buffalo

9h 26m1 stop Chicago O'Hare Intl

$1,032American Airlines

Sun, Oct 25 - Wed, Oct 28

8:45 am - 12:55 pmBUF Buffalo-SAN San Diego

7h 10m1 stop Denver Intl

6:50 am - 5:02 pmSAN San Diego-BUF Buffalo

7h 12m1 stop Chicago O'Hare Intl

$1,032United Airlines

Sat, Oct 24 - Tue, Oct 27

11:24 am - 8:20 pmBUF Buffalo-SAN San Diego

11h 56m2 stops Chicago O'Hare Intl Portland

8:26 pm - 11:08 amSAN San Diego-BUF Buffalo

11h 42m1 stop Boston Logan Intl

$1,034Multiple Airlines

Fri, Oct 23 - Sun, Oct 25

9:00 am - 3:45 pmBUF Buffalo-SAN San Diego

9h 45m2 stops Baltimore/Washington Phoenix Sky Harbor Intl

12:25 pm - 11:50 pmSAN San Diego-BUF Buffalo

8h 25m1 stop Las Vegas Harry Reid Intl

$1,037Southwest

Sun, Oct 25 - Wed, Oct 28

9:00 am - 3:45 pmBUF Buffalo-SAN San Diego

9h 45m2 stops Baltimore/Washington Phoenix Sky Harbor Intl

8:30 am - 8:35 pmSAN San Diego-BUF Buffalo

9h 05m2 stops Phoenix Sky Harbor Intl Chicago Midway

$1,042Southwest

Sun, Oct 25 - Wed, Oct 28

11:24 am - 9:34 pmBUF Buffalo-SAN San Diego

13h 10m1 stop Chicago O'Hare Intl

6:15 am - 11:59 pmSAN San Diego-BUF Buffalo

14h 44m1 stop Chicago O'Hare Intl

$1,091American Airlines

Fri, Oct 23 - Mon, Oct 26

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Southwest flights from Buffalo to San Diego

Our best Southwest deals on Buffalo to San Diego flight tickets

Southwest

Dec 3

BUF6:55 pmBuffalo

7h 30m

1 stop

SAN11:25 pmSan Diego

Dec 9

SAN6:35 amSan Diego

8h 35m

1 stop

BUF6:10 pmBuffalo

$227

Southwest

Jan 23

BUF4:20 pmBuffalo

7h 20m

1 stop

SAN8:40 pmSan Diego

Jan 30

SAN12:25 pmSan Diego

7h 05m

1 stop

BUF10:30 pmBuffalo

$228

Southwest

Dec 3

BUF6:55 pmBuffalo

7h 30m

1 stop

SAN11:25 pmSan Diego

Dec 9

SAN8:15 amSan Diego

9h 40m

2 stops

BUF8:55 pmBuffalo

$232

American Airlines flights from Buffalo to San Diego

Our best American Airlines deals on Buffalo to San Diego flight tickets

American Airlines

Dec 17

BUF6:04 amBuffalo

10h 09m

1 stop

SAN1:13 pmSan Diego

Jan 7

SAN11:44 amSan Diego

8h 29m

1 stop

BUF11:13 pmBuffalo

$253

American Airlines

Feb 10

BUF12:49 pmBuffalo

10h 54m

1 stop

SAN8:43 pmSan Diego

Feb 24

SAN2:00 pmSan Diego

6h 48m

1 stop

BUF11:48 pmBuffalo

$259

American Airlines

Dec 2

BUF6:49 pmBuffalo

8h 10m

1 stop

SAN11:59 pmSan Diego

Dec 6

SAN11:34 amSan Diego

7h 21m

1 stop

BUF9:55 pmBuffalo

$272

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Thu 12/10

11:30 am-7:33 pm

1 stop11h 03m

San Diego

Mon 12/14

9:40 pm-9:34 am

1 stop8h 54m

$226

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Thu 12/10

11:30 am-7:33 pm

1 stop11h 03m

San Diego

Sat 1/9

9:45 pm-8:22 am

1 stop7h 37m

$226

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Tue 1/5

5:00 pm-11:10 pm

1 stop9h 10m

San Diego

Tue 1/26

9:55 pm-8:05 am

1 stop7h 10m

$227

Quickest round-trip

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Thu 12/3

6:55 pm-11:25 pm

1 stop7h 30m

San Diego

Wed 12/9

6:35 am-6:10 pm

1 stop8h 35m

$227

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Tue 12/8

12:50 pm-8:48 pm

1 stop10h 58m

San Diego

Wed 1/6

11:43 am-11:28 pm

1 stop8h 45m

$227

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Thu 12/10

7:00 am-2:23 pm

1 stop10h 23m

San Diego

Tue 12/15

10:14 am-9:55 pm

1 stop8h 41m

$227

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Wed 11/11

5:58 pm-10:40 pm

1 stop7h 42m

San Diego

Mon 11/16

9:45 pm-10:08 am

2 stops9h 23m

$242

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Sat 1/16

1:50 pm-8:08 pm

2 stops9h 18m

San Diego

Sat 1/23

7:00 am-7:32 pm

1 stop9h 32m

$242

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Mon 12/7

6:41 pm-11:38 pm

1 stop7h 57m

San Diego

Thu 1/7

10:40 pm-11:15 am

1 stop9h 35m

$297

BuffaloSan Diego

BUF Buffalo - SAN San Diego

BUFSAN

Buffalo

Fri 11/20

6:35 am-10:26 am

1 stop6h 51m

San Diego

Thu 11/26

8:00 am-9:04 pm

1 stop10h 04m

$297

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Buffalo to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Buffalo and San Diego?

Prices are currently low for flights on this route.

Typical prices usually range from $334 to $548.
The lowest price recently found on this route was $226.

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of April, then departing from Buffalo during the month January is also very affordable. Most momondo users find prices during this month for around $381.

How far in advance should I book a flight from Buffalo to San Diego?

You are more likely to see cheaper flights to San Diego from Buffalo when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $402 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Buffalo for as low as $312 on momondo.

Can stopping save me money on Buffalo to San Diego flights?

You could potentially save up to 31% on your flight if you consider stops on a Buffalo to San Diego flight.

How have Buffalo to San Diego flight prices changed over time?

As of October 2026, prices for Buffalo to San Diego flights are approximately 34% cheaper when compared to flights at the same time last year.

When to book flights from Buffalo to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to San Diego according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Buffalo to San Diego (BUF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to San Diego

Best Price Found	$114
Fastest flight time	6h 51m
Direct flights	None

The best one-way flight to San Diego from Buffalo in the past 72 hours is $114. The best round-trip flight deal from Buffalo to San Diego found on momondo in the last 72 hours is $226.

The fastest flight from Buffalo to San Diego takes 6h 51m

There are no direct flights from Buffalo to San Diego. There are no popular flight routes from Buffalo to San Diego.

Search flight deals

Frequently asked questions about flying from Buffalo to San Diego

How far is Buffalo to San Diego by plane?
There are 2181.7 mi between Buffalo and San Diego. Typically, this will take 6h 51m by plane in normal conditions.
When did momondo last update prices for flights from Buffalo Airport to San Diego Airport?
Prices for flights from Buffalo Airport to San Diego Airport are updated daily.
How many operators does momondo search for flights from Buffalo Airport to San Diego Airport?
There are 5 operators available for flights from Buffalo Airport to San Diego Airport as of October 2026.
How old do you have to be to fly from Buffalo Airport to San Diego Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to San Diego Airport.
What documentation or ID do you need to fly to San Diego Airport?
The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Buffalo to San Diego?
Based on momondo bookings for flights between Buffalo and San Diego, the leading plane model is Boeing 737 MAX 8, making up 100.00% of the total bookings.
What is the most popular airline from Buffalo to San Diego?
momondo data reveals that the most frequently booked airline on the route from Buffalo to San Diego is Southwest, representing 28% of all bookings. The subsequent popular airlines are American Airlines at 24%, Delta at 23%, and United Airlines at 18%.

Best airlines flying from Buffalo to San Diego

Compare and see reviews for airlines that fly from Buffalo to San Diego with momondo

Airline	Rating	Free Cancellation	Price
JetBlue	PriceFrom $172	Free Cancellation	Rating 7.1 3,059 reviews	Search JetBlue flights
Delta	PriceFrom $264	Free Cancellation	Rating 7.8 8,661 reviews	Search Delta flights
American Airlines	PriceFrom $270	Free Cancellation	Rating 7.0 12,184 reviews	Search American Airlines flights
United Airlines	PriceFrom $296	Free Cancellation	Rating 7.3 10,399 reviews	Search United Airlines flights
Southwest	PriceFrom $296	Free Cancellation	Rating 7.9 4,208 reviews	Search Southwest flights

Chula Vista

El Cajon

Coronado

National City

La Mesa

Julian

San Ysidro

Poway

Santee

Imperial Beach

Alpine

Lemon Grove

Borrego Springs

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Buffalo.

Can I find flights from Buffalo to San Diego with flexible booking policies on momondo?

Flights from Buffalo to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to San Diego?

momondo helps you find the best flight between Buffalo and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Sat 11/21

Sat 11/28

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Nearby airports

Airlines

Cabin classes

Other United States destinations

Other flights from Buffalo

Complete your trip

Feeling lucky

Cheap flights from Buffalo to San Diego from $114

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to San Diego departing on 1/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Find the cheapest flights from Buffalo to San Diego

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Southwest flights from Buffalo to San Diego

Our best Southwest deals on Buffalo to San Diego flight tickets

American Airlines flights from Buffalo to San Diego

Our best American Airlines deals on Buffalo to San Diego flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Buffalo to San Diego that are best for you.

See travel insights to San Diego from

How to get the cheapest flight ticket from Buffalo to San Diego

What is the typical price of a round-trip flight between Buffalo and San Diego?

What is the cheapest month to fly to San Diego?

How far in advance should I book a flight from Buffalo to San Diego?

Can stopping save me money on Buffalo to San Diego flights?

How have Buffalo to San Diego flight prices changed over time?

What is the cheapest airline that flies from Buffalo to San Diego?

What airlines fly to San Diego?

When to book flights from Buffalo to San Diego

Cheap Buffalo to San Diego (BUF to SAN) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Buffalo to San Diego

Best airlines flying from Buffalo to San Diego

Compare and see reviews for airlines that fly from Buffalo to San Diego with momondo

Traveling to a place near San Diego?

Why use momondo?

An easier way to manage your San Diego trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing California

Fly your favorite airline to San Diego

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to San Diego

List of cabin classes available on flights landing in San Diego. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from Buffalo

According to popular flight searches on momondo this year

Complete your trip to San Diego

Explore popular destinations other users love

According to popular flight searches on momondo this year