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Cheap flights from Buffalo to San Diego from $126

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to San Diego departing on 4/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Buffalo to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
3:10 pm - 7:35 pm
BUF
-
SAN
7h 25m
1 stop
Southwest Logo
9:40 pm - 7:50 am
SAN
-
BUF
7h 10m
1 stop
$249Southwest
Tue, Apr 14 - Thu, Apr 16
United Airlines Logo
5:57 pm - 10:59 pm
BUF
-
SAN
8h 02m
1 stop
United Airlines Logo
11:00 am - 11:10 pm
SAN
-
BUF
9h 10m
1 stop
$251United Airlines
Wed, Apr 15 - Wed, Apr 22
United Airlines Logo
10:55 am - 5:16 pm
BUF
-
SAN
9h 21m
2 stops
United Airlines Logo
10:52 am - 8:43 pm
SAN
-
BUF
6h 51m
1 stop
$256United Airlines
Wed, Apr 15 - Tue, Apr 21
American Airlines Logo
6:00 am - 12:28 pm
BUF
-
SAN
9h 28m
1 stop
American Airlines Logo
10:40 pm - 10:50 am
SAN
-
BUF
9h 10m
1 stop
$262American Airlines
Wed, May 13 - Tue, May 19
American Airlines Logo
3:01 pm - 8:43 pm
BUF
-
SAN
8h 42m
1 stop
American Airlines Logo
10:40 pm - 10:50 am
SAN
-
BUF
9h 10m
1 stop
$264American Airlines
Wed, Apr 8 - Wed, Apr 15
Southwest Logo
1:10 pm - 7:35 pm
BUF
-
SAN
9h 25m
2 stops
Southwest Logo
10:40 pm - 10:20 am
SAN
-
BUF
8h 40m
1 stop
$265Southwest
Wed, Apr 8 - Tue, Apr 14
Southwest Logo
3:10 pm - 9:45 pm
BUF
-
SAN
9h 35m
2 stops
Southwest Logo
10:40 pm - 10:15 am
SAN
-
BUF
8h 35m
1 stop
$278Southwest
Tue, Apr 14 - Thu, Apr 16
United Airlines Logo
5:50 pm - 11:59 pm
BUF
-
SAN
9h 09m
2 stops
United Airlines Logo
7:20 am - 6:17 pm
SAN
-
BUF
7h 57m
1 stop
$279United Airlines
Fri, May 1 - Sat, May 2
American Airlines Logo
6:00 pm - 11:33 pm
BUF
-
SAN
8h 33m
1 stop
American Airlines Logo
10:40 pm - 10:50 am
SAN
-
BUF
9h 10m
1 stop
$285American Airlines
Mon, Apr 20 - Sat, Apr 25
Southwest Logo
4:00 pm - 10:00 pm
BUF
-
SAN
9h 00m
1 stop
Southwest Logo
9:40 pm - 7:50 am
SAN
-
BUF
7h 10m
1 stop
$289Southwest
Thu, Apr 9 - Mon, Apr 13

Southwest flights from Buffalo to San Diego

Our best Southwest deals on Buffalo to San Diego flight tickets
Southwest
Apr 14
BUF3:10 pmBuffalo
7h 25m
1 stop
SAN7:35 pmSan Diego
Apr 16
SAN9:40 pmSan Diego
7h 10m
1 stop
BUF7:50 amBuffalo
$249
Southwest
Apr 8
BUF1:10 pmBuffalo
9h 25m
2 stops
SAN7:35 pmSan Diego
Apr 14
SAN10:40 pmSan Diego
8h 40m
1 stop
BUF10:20 amBuffalo
$265
Southwest
Apr 21
BUF1:10 pmBuffalo
9h 25m
2 stops
SAN7:35 pmSan Diego
Apr 23
SAN9:40 pmSan Diego
7h 10m
1 stop
BUF7:50 amBuffalo
$271

American Airlines flights from Buffalo to San Diego

Our best American Airlines deals on Buffalo to San Diego flight tickets
American Airlines
Apr 8
BUF6:00 amBuffalo
10h 14m
1 stop
SAN1:14 pmSan Diego
Apr 14
SAN10:30 pmSan Diego
8h 48m
1 stop
BUF10:18 amBuffalo
$251
American Airlines
May 13
BUF6:00 amBuffalo
9h 28m
1 stop
SAN12:28 pmSan Diego
May 19
SAN10:40 pmSan Diego
9h 10m
1 stop
BUF10:50 amBuffalo
$262
American Airlines
Apr 8
BUF3:01 pmBuffalo
8h 42m
1 stop
SAN8:43 pmSan Diego
Apr 15
SAN10:40 pmSan Diego
9h 10m
1 stop
BUF10:50 amBuffalo
$264

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 24, 2026.
Use the filters below to find and compare flights from Buffalo to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 4/14

3:10 pm-7:35 pm

1 stop7h 25m

San Diego

Thu 4/16

9:40 pm-7:50 am

1 stop7h 10m

$249

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 4/15

5:57 pm-10:59 pm

1 stop8h 02m

San Diego

Wed 4/22

11:00 am-11:10 pm

1 stop9h 10m

$251

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 4/15

10:55 am-5:16 pm

2 stops9h 21m

San Diego

Tue 4/21

10:52 am-8:43 pm

1 stop6h 51m

$256

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 5/13

6:00 am-12:28 pm

1 stop9h 28m

San Diego

Tue 5/19

10:40 pm-10:50 am

1 stop9h 10m

$262

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 4/8

3:01 pm-8:43 pm

1 stop8h 42m

San Diego

Wed 4/15

10:40 pm-10:50 am

1 stop9h 10m

$264

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 4/8

1:10 pm-7:35 pm

2 stops9h 25m

San Diego

Tue 4/14

10:40 pm-10:20 am

1 stop8h 40m

$265

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 4/14

3:10 pm-9:45 pm

2 stops9h 35m

San Diego

Thu 4/16

10:40 pm-10:15 am

1 stop8h 35m

$278

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Fri 5/1

5:50 pm-11:59 pm

2 stops9h 09m

San Diego

Sat 5/2

7:20 am-6:17 pm

1 stop7h 57m

$279

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Mon 4/20

6:00 pm-11:33 pm

1 stop8h 33m

San Diego

Sat 4/25

10:40 pm-10:50 am

1 stop9h 10m

$285

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 4/9

4:00 pm-10:00 pm

1 stop9h 00m

San Diego

Mon 4/13

9:40 pm-7:50 am

1 stop7h 10m

$289

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Buffalo to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Buffalo during the month November is also very affordable. Most momondo users find prices during this month for around $356.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Buffalo when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $402 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Buffalo for as low as $288 on momondo.

Can stopping save me money on Buffalo to San Diego flights?

You could potentially save up to 25% on your flight if you consider stops on a Buffalo to San Diego flight.

How have Buffalo to San Diego flight prices changed over time?

As of February 2026, prices for Buffalo to San Diego flights are approximately 73% more expensive when compared to flights at the same time last year.

When to book flights from Buffalo to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to San Diego (BUF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to San Diego

Fastest flight time

6h 44m

Direct flights

None
The fastest flight from Buffalo to San Diego takes 6h 44m
There are no direct flights from Buffalo to San Diego. There are no popular flight routes from Buffalo to San Diego.
Search flight deals

  • How far is Buffalo to San Diego by plane?

    There are 2181.7 mi between Buffalo and San Diego. Typically, this will take 6h 44m by plane in normal conditions.

  • When did momondo last update prices for flights from Buffalo Airport to San Diego Airport?

    Prices for flights from Buffalo Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Buffalo Airport to San Diego Airport?

  • How old do you have to be to fly from Buffalo Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Buffalo to San Diego?

  • What is the most popular airline from Buffalo to San Diego?

Best airlines flying from Buffalo to San Diego

Compare and see reviews for airlines that fly from Buffalo to San Diego with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $99Free CancellationRating
5.7
3,043 reviews
Search Frontier flights
JetBluePriceFrom $172Free CancellationRating
7.2
2,900 reviews
Search JetBlue flights
DeltaPriceFrom $218Free CancellationRating
7.9
8,239 reviews
Search Delta flights
SouthwestPriceFrom $230Free CancellationRating
8.0
4,300 reviews
Search Southwest flights
American AirlinesPriceFrom $250Free CancellationRating
7.2
11,344 reviews
Search American Airlines flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
9,344 reviews
Search United Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
Poway
National City
Imperial Beach
San Ysidro
Borrego Springs
La Mesa
Alpine
Lemon Grove
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Buffalo.

Can I find flights from Buffalo to San Diego with flexible booking policies on momondo?

Flights from Buffalo to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to San Diego?

momondo helps you find the best flight between Buffalo and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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