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Cheap flights from Buffalo to San Diego from $157

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Buffalo to San Diego departing on 6/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Buffalo to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
3:00 pm - 7:35 pm
BUF
-
SAN
7h 35m
1 stop
Southwest Logo
4:05 pm - 1:30 am
SAN
-
BUF
6h 25m
1 stop
$344Southwest
Wed, Aug 12 - Sun, Aug 16
Delta Logo
3:53 pm - 11:42 pm
BUF
-
SAN
10h 49m
1 stop
Delta Logo
2:49 pm - 11:59 pm
SAN
-
BUF
6h 10m
1 stop
$348Delta
Sat, Jun 6 - Wed, Jun 17
Delta Logo
4:30 pm - 10:44 pm
BUF
-
SAN
9h 14m
1 stop
Delta Logo
10:10 pm - 10:35 am
SAN
-
BUF
9h 25m
1 stop
$349Delta
Wed, Sep 2 - Tue, Sep 8
American Airlines Logo
2:47 pm - 8:53 pm
BUF
-
SAN
9h 06m
1 stop
American Airlines Logo
6:50 am - 6:39 pm
SAN
-
BUF
8h 49m
1 stop
$350American Airlines
Sun, May 24 - Sat, May 30
Delta Logo
3:53 pm - 11:42 pm
BUF
-
SAN
10h 49m
1 stop
Delta Logo
10:15 pm - 8:23 am
SAN
-
BUF
7h 08m
1 stop
$354Delta
Thu, May 28 - Fri, Jun 12
American Airlines Logo
1:03 pm - 7:18 pm
BUF
-
SAN
9h 15m
1 stop
American Airlines Logo
12:04 pm - 11:01 pm
SAN
-
BUF
7h 57m
1 stop
$356American Airlines
Mon, Aug 31 - Sun, Sep 6
Delta Logo
3:53 pm - 11:42 pm
BUF
-
SAN
10h 49m
1 stop
Delta Logo
2:49 pm - 11:59 pm
SAN
-
BUF
6h 10m
1 stop
$358Delta
Sat, Jun 6 - Tue, Jun 16
Southwest Logo
12:35 pm - 6:20 pm
BUF
-
SAN
8h 45m
2 stops
Southwest Logo
7:00 am - 8:35 pm
SAN
-
BUF
10h 35m
2 stops
$359Southwest
Wed, Sep 23 - Tue, Sep 29
Southwest Logo
12:35 pm - 6:40 pm
BUF
-
SAN
9h 05m
2 stops
Southwest Logo
10:40 pm - 11:20 am
SAN
-
BUF
9h 40m
1 stop
$360Southwest
Wed, Sep 2 - Mon, Sep 7
American Airlines Logo
1:56 pm - 6:50 pm
BUF
-
SAN
7h 54m
1 stop
American Airlines Logo
6:15 am - 6:04 pm
SAN
-
BUF
8h 49m
1 stop
$363American Airlines
Tue, Aug 4 - Tue, Aug 11

American Airlines flights from Buffalo to San Diego

Our best American Airlines deals on Buffalo to San Diego flight tickets
American Airlines
May 24
BUF2:47 pmBuffalo
9h 06m
1 stop
SAN8:53 pmSan Diego
May 30
SAN10:57 amSan Diego
8h 39m
1 stop
BUF10:36 pmBuffalo
$349
American Airlines
May 24
BUF2:47 pmBuffalo
9h 06m
1 stop
SAN8:53 pmSan Diego
May 30
SAN6:50 amSan Diego
8h 49m
1 stop
BUF6:39 pmBuffalo
$350
American Airlines
May 24
BUF2:47 pmBuffalo
9h 06m
1 stop
SAN8:53 pmSan Diego
May 30
SAN10:57 amSan Diego
8h 39m
1 stop
BUF10:36 pmBuffalo
$354

Southwest flights from Buffalo to San Diego

Our best Southwest deals on Buffalo to San Diego flight tickets
Southwest
Aug 12
BUF3:00 pmBuffalo
7h 35m
1 stop
SAN7:35 pmSan Diego
Aug 16
SAN4:05 pmSan Diego
6h 25m
1 stop
BUF1:30 amBuffalo
$344
Southwest
Sep 23
BUF12:35 pmBuffalo
8h 45m
2 stops
SAN6:20 pmSan Diego
Sep 29
SAN7:00 amSan Diego
10h 35m
2 stops
BUF8:35 pmBuffalo
$359
Southwest
Sep 2
BUF12:35 pmBuffalo
9h 05m
2 stops
SAN6:40 pmSan Diego
Sep 7
SAN10:40 pmSan Diego
9h 40m
1 stop
BUF11:20 amBuffalo
$360

momondo Fare Finder

 
Customize your flight search to find flights from Buffalo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Buffalo to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 8/12

3:00 pm-7:35 pm

1 stop7h 35m

San Diego

Sun 8/16

4:05 pm-1:30 am

1 stop6h 25m

$344

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Sat 6/6

3:53 pm-11:42 pm

1 stop10h 49m

San Diego

Wed 6/17

2:49 pm-11:59 pm

1 stop6h 10m

$348

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 9/2

4:30 pm-10:44 pm

1 stop9h 14m

San Diego

Tue 9/8

10:10 pm-10:35 am

1 stop9h 25m

$349

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Sun 5/24

2:47 pm-8:53 pm

1 stop9h 06m

San Diego

Sat 5/30

6:50 am-6:39 pm

1 stop8h 49m

$350

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Thu 5/28

3:53 pm-11:42 pm

1 stop10h 49m

San Diego

Fri 6/12

10:15 pm-8:23 am

1 stop7h 08m

$354

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Mon 8/31

1:03 pm-7:18 pm

1 stop9h 15m

San Diego

Sun 9/6

12:04 pm-11:01 pm

1 stop7h 57m

$356

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Sat 6/6

3:53 pm-11:42 pm

1 stop10h 49m

San Diego

Tue 6/16

2:49 pm-11:59 pm

1 stop6h 10m

$358

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 9/23

12:35 pm-6:20 pm

2 stops8h 45m

San Diego

Tue 9/29

7:00 am-8:35 pm

2 stops10h 35m

$359

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Wed 9/2

12:35 pm-6:40 pm

2 stops9h 05m

San Diego

Mon 9/7

10:40 pm-11:20 am

1 stop9h 40m

$360

BuffaloSan Diego

BUF - SAN

BUFSAN

Buffalo

Tue 8/4

1:56 pm-6:50 pm

1 stop7h 54m

San Diego

Tue 8/11

6:15 am-6:04 pm

1 stop8h 49m

$363

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Buffalo to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Buffalo and San Diego?

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of October, then departing from Buffalo during the month April is also very affordable. Most momondo users find prices during this month for around $366.

How far in advance should I book a flight from Buffalo to San Diego?

You are more likely to see cheaper flights to San Diego from Buffalo when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $392 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Buffalo for as low as $281 on momondo.

Can stopping save me money on Buffalo to San Diego flights?

You could potentially save up to 36% on your flight if you consider stops on a Buffalo to San Diego flight.

How have Buffalo to San Diego flight prices changed over time?

As of May 2026, prices for Buffalo to San Diego flights are approximately 17% more expensive when compared to flights at the same time last year.

When to book flights from Buffalo to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Buffalo to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Buffalo to San Diego (BUF to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Buffalo to San Diego

Fastest flight time

6h 53m

Direct flights

None
The fastest flight from Buffalo to San Diego takes 6h 53m
There are no direct flights from Buffalo to San Diego. There are no popular flight routes from Buffalo to San Diego.
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Frequently asked questions about flying from Buffalo to San Diego

  • How far is Buffalo to San Diego by plane?

    There are 2181.7 mi between Buffalo and San Diego. Typically, this will take 6h 53m by plane in normal conditions.

  • When did momondo last update prices for flights from Buffalo Airport to San Diego Airport?

    Prices for flights from Buffalo Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Buffalo Airport to San Diego Airport?

  • How old do you have to be to fly from Buffalo Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Buffalo Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Buffalo to San Diego?

  • What is the most popular airline from Buffalo to San Diego?

Best airlines flying from Buffalo to San Diego

Compare and see reviews for airlines that fly from Buffalo to San Diego with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $172Free CancellationRating
7.1
2,973 reviews
Search JetBlue flights
DeltaPriceFrom $222Free CancellationRating
7.9
8,451 reviews
Search Delta flights
American AirlinesPriceFrom $245Free CancellationRating
7.1
11,666 reviews
Search American Airlines flights
SouthwestPriceFrom $267Free CancellationRating
8.0
4,298 reviews
Search Southwest flights
United AirlinesPriceFrom $296Free CancellationRating
7.4
9,699 reviews
Search United Airlines flights

  • Southwest Flights From Buffalo to San Diego

    Southwest flight deals from Buffalo to San Diego start from $267 round-trip. Over the 1 Southwest flight for this route in a normal week, average airfare is usually $405 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Poway
San Ysidro
La Mesa
Imperial Beach
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Buffalo to San Diego?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Diego from Buffalo.

Can I find flights from Buffalo to San Diego with flexible booking policies on momondo?

Flights from Buffalo to San Diego with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Buffalo to San Diego?

momondo helps you find the best flight between Buffalo and San Diego by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Buffalo to San Diego right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Buffalo to San Diego flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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