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Cheap flights from St. Louis to Los Angeles from $111

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Los Angeles departing on 6/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:51 pm - 12:19 pm
STL
-
SNA
19h 28m
1 stop
Frontier Logo
9:54 am - 7:23 pm
SNA
-
STL
7h 29m
1 stop
$185Frontier
Wed, May 20 - Sat, May 23
Frontier Logo
8:08 pm - 9:25 am
STL
-
SNA
15h 17m
1 stop
Frontier Logo
7:54 pm - 6:05 pm
SNA
-
STL
20h 11m
1 stop
$230Frontier
Wed, Jul 8 - Mon, Jul 13
Frontier Logo
8:08 pm - 9:09 am
STL
-
SNA
15h 01m
1 stop
Frontier Logo
9:54 am - 7:23 pm
SNA
-
STL
7h 29m
1 stop
$240Frontier
Sat, May 23 - Sat, May 30
Frontier Logo
9:06 pm - 12:19 pm
STL
-
SNA
17h 13m
1 stop
Frontier Logo
9:54 am - 7:23 pm
SNA
-
STL
7h 29m
1 stop
$271Frontier
Thu, May 21 - Sun, May 24
Multiple Airlines Logo
7:03 pm - 2:15 pm
STL
-
SNA
21h 12m
2 stops
Multiple Airlines Logo
4:24 pm - 6:18 pm
SNA
-
STL
23h 54m
1 stop
$274Multiple Airlines
Wed, Jun 17 - Thu, Jun 25
Multiple Airlines Logo
4:19 pm - 12:15 pm
STL
-
SNA
21h 56m
1 stop
Multiple Airlines Logo
8:10 pm - 7:23 pm
SNA
-
STL
21h 13m
2 stops
$277Multiple Airlines
Mon, Jun 1 - Mon, Jun 8
Multiple Airlines Logo
7:03 pm - 2:15 pm
STL
-
SNA
21h 12m
2 stops
Multiple Airlines Logo
4:24 pm - 6:18 pm
SNA
-
STL
23h 54m
1 stop
$279Multiple Airlines
Wed, Jun 17 - Mon, Jun 22
Frontier Logo
9:06 pm - 12:19 pm
STL
-
SNA
17h 13m
1 stop
Frontier Logo
9:54 am - 7:23 pm
SNA
-
STL
7h 29m
1 stop
$280Frontier
Thu, May 21 - Sun, May 24
Frontier Logo
4:52 pm - 1:42 pm
STL
-
SNA
22h 50m
2 stops
Frontier Logo
8:55 am - 7:23 pm
SNA
-
STL
8h 28m
1 stop
$293Frontier
Wed, Aug 12 - Mon, Aug 17
Frontier Logo
8:08 pm - 12:00 pm
STL
-
SNA
17h 52m
2 stops
Frontier Logo
8:10 pm - 6:08 pm
SNA
-
STL
19h 58m
1 stop
$301Frontier
Fri, Aug 21 - Mon, Aug 31

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Frontier flights from St. Louis to Santa Ana, California

Our best Frontier deals on St. Louis to Santa Ana, California flight tickets
Frontier
May 20
STL6:51 pmLambert-St Louis
19h 28m
1 stop
SNA12:19 pmSanta Ana J. Wayne/Orange Cnty
May 23
SNA9:54 amSanta Ana J. Wayne/Orange Cnty
7h 29m
1 stop
STL7:23 pmLambert-St Louis
$185
Frontier
Jul 8
STL8:08 pmLambert-St Louis
15h 17m
1 stop
SNA9:25 amSanta Ana J. Wayne/Orange Cnty
Jul 13
SNA7:54 pmSanta Ana J. Wayne/Orange Cnty
20h 11m
1 stop
STL6:05 pmLambert-St Louis
$230
Frontier
May 23
STL8:08 pmLambert-St Louis
15h 01m
1 stop
SNA9:09 amSanta Ana J. Wayne/Orange Cnty
May 30
SNA9:54 amSanta Ana J. Wayne/Orange Cnty
7h 29m
1 stop
STL7:23 pmLambert-St Louis
$240

Alaska Airlines flights from St. Louis to Santa Ana, California

Our best Alaska Airlines deals on St. Louis to Santa Ana, California flight tickets
Alaska Airlines
May 19
STL6:00 amLambert-St Louis
10h 43m
1 stop
SNA2:43 pmSanta Ana J. Wayne/Orange Cnty
May 23
SNA1:58 pmSanta Ana J. Wayne/Orange Cnty
7h 56m
1 stop
STL11:54 pmLambert-St Louis
$677
Alaska Airlines
May 16
STL4:12 pmLambert-St Louis
8h 18m
1 stop
SNA10:30 pmSanta Ana J. Wayne/Orange Cnty
May 22
SNA7:00 amSanta Ana J. Wayne/Orange Cnty
7h 37m
1 stop
STL4:37 pmLambert-St Louis
$753
Alaska Airlines
May 8
STL7:00 amLambert-St Louis
17h 30m
2 stops
SNA10:30 pmSanta Ana J. Wayne/Orange Cnty
May 9
SNA10:53 amSanta Ana J. Wayne/Orange Cnty
11h 06m
2 stops
STL11:59 pmLambert-St Louis
$955

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from St. Louis to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 5/20

6:51 pm-12:19 pm

1 stop19h 28m

Santa Ana J. Wayne/Orange Cnty

Sat 5/23

9:54 am-7:23 pm

1 stop7h 29m

$185

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 7/8

8:08 pm-9:25 am

1 stop15h 17m

Santa Ana J. Wayne/Orange Cnty

Mon 7/13

7:54 pm-6:05 pm

1 stop20h 11m

$230
Quickest round-trip

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sat 5/23

8:08 pm-9:09 am

1 stop15h 01m

Santa Ana J. Wayne/Orange Cnty

Sat 5/30

9:54 am-7:23 pm

1 stop7h 29m

$240

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 5/21

9:06 pm-12:19 pm

1 stop17h 13m

Santa Ana J. Wayne/Orange Cnty

Sun 5/24

9:54 am-7:23 pm

1 stop7h 29m

$271

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 6/17

7:03 pm-2:15 pm

2 stops21h 12m

Santa Ana J. Wayne/Orange Cnty

Thu 6/25

4:24 pm-6:18 pm

1 stop23h 54m

$274

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 6/1

4:19 pm-12:15 pm

1 stop21h 56m

Santa Ana J. Wayne/Orange Cnty

Mon 6/8

8:10 pm-7:23 pm

2 stops21h 13m

$277

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 6/17

7:03 pm-2:15 pm

2 stops21h 12m

Santa Ana J. Wayne/Orange Cnty

Mon 6/22

4:24 pm-6:18 pm

1 stop23h 54m

$279

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 5/21

9:06 pm-12:19 pm

1 stop17h 13m

Santa Ana J. Wayne/Orange Cnty

Sun 5/24

9:54 am-7:23 pm

1 stop7h 29m

$280

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 8/12

4:52 pm-1:42 pm

2 stops22h 50m

Santa Ana J. Wayne/Orange Cnty

Mon 8/17

8:55 am-7:23 pm

1 stop8h 28m

$293

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 8/21

8:08 pm-12:00 pm

2 stops17h 52m

Santa Ana J. Wayne/Orange Cnty

Mon 8/31

8:10 pm-6:08 pm

1 stop19h 58m

$301

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from St. Louis to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between St. Louis and Santa Ana, California?

What is the cheapest month to fly to Santa Ana, California?

In general, November is the cheapest month to fly from St. Louis to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $345. If you aren’t able to travel during the month of November, then book flights to Santa Ana, California from St. Louis during April instead. Flights to Santa Ana, California in April, while not as cheap as those in November, still average around $368.

How far in advance should I book a flight from St. Louis to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $450 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from St. Louis for as low as $338 on momondo.

How have St. Louis to Santa Ana, California flight prices changed over time?

As of May 2026, prices for St. Louis to Santa Ana, California flights are approximately 105% more expensive when compared to flights at the same time last year.

When to book flights from St. Louis to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Santa Ana, California (STL to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santa Ana, California

Fastest flight time

5h 44m

Direct flights

None
The fastest flight from St. Louis to Santa Ana, California takes 5h 44m
There are no direct flights from St. Louis to Santa Ana, California. There are no popular flight routes from St. Louis to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from St. Louis to Santa Ana, California

  • How far is Lambert-St Louis to Santa Ana J. Wayne/Orange Cnty by plane?

    Lambert-St Louis and Santa Ana J. Wayne/Orange Cnty are 1572.0 mi apart from one another. A reasonable flight in good conditions will take 5h 44m.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from St. Louis to Santa Ana, California?

Best airlines flying from St. Louis to Santa Ana, California

Compare and see reviews for airlines that fly from St. Louis to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,667 reviews
Search American Airlines flights
United AirlinesPriceFrom $286Free CancellationRating
7.4
9,683 reviews
Search United Airlines flights
SouthwestPriceFrom $316Free CancellationRating
7.9
4,305 reviews
Search Southwest flights

  • Southwest Flights From St. Louis to Santa Ana, California

    Southwest is one of the most popular airlines flying from St. Louis to Santa Ana, California, operating 3 flights/week on average for this route. A good Southwest flight deal for St. Louis to Santa Ana, California starts from $316 round-trip, up to an average price of $561. Our users have rated Southwest at 7.9/10.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from St. Louis to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from St. Louis to Santa Ana with flexible booking policies on momondo?

All flight searches from St. Louis to Santa Ana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from St. Louis to Santa Ana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Ana from St. Louis.

I’m not ready to book a flight from St. Louis to Santa Ana right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santa Ana from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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