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Cheap flights from St. Louis to Los Angeles from $113

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Los Angeles departing on 10/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Spirit Airlines Logo
12:05 pm - 11:35 amSTL-SNA
25h 30m1 stop
Spirit Airlines Logo
12:32 pm - 10:50 amSNA-STL
20h 18m1 stop
$219Spirit Airlines
Find Deal
jue., sep. 25 - sáb., sep. 27
Frontier Logo
7:54 pm - 11:27 amSTL-SNA
17h 33m1 stop
Frontier Logo
12:58 pm - 9:06 amSNA-STL
18h 08m1 stop
$225Frontier
Find Deal
mar., sep. 2 - sáb., sep. 6
American Airlines Logo
7:01 am - 11:38 amSTL-SNA
6h 37m1 stop
American Airlines Logo
10:38 am - 10:17 pmSNA-STL
9h 39m1 stop
$267American Airlines
Find Deal
jue., ago. 28 - mar., sep. 2
American Airlines Logo
7:53 am - 11:57 amSTL-SNA
6h 04m1 stop
American Airlines Logo
12:50 pm - 10:50 pmSNA-STL
8h 00m2 stops
$272American Airlines
Find Deal
mar., sep. 2 - sáb., sep. 6
Southwest Logo
5:20 am - 10:50 amSTL-SNA
7h 30m1 stop
Southwest Logo
7:30 am - 5:00 pmSNA-STL
7h 30m2 stops
$277Southwest
Find Deal
dom., nov. 2 - sáb., nov. 8
United Airlines Logo
5:15 am - 9:16 amSTL-SNA
6h 01m1 stop
United Airlines Logo
10:30 am - 9:32 pmSNA-STL
9h 02m1 stop
$279United Airlines
Find Deal
mar., ago. 19 - sáb., ago. 23
Southwest Logo
4:35 pm - 9:10 pmSTL-SNA
6h 35m1 stop
Southwest Logo
6:45 am - 6:35 pmSNA-STL
9h 50m2 stops
$282Southwest
Find Deal
mar., sep. 2 - vie., sep. 5
Delta Logo
2:29 pm - 10:17 pmSTL-SNA
9h 48m2 stops
Delta Logo
5:05 pm - 12:37 amSNA-STL
5h 32m1 stop
$315Delta
Find Deal
mié., nov. 5 - lun., nov. 10
Delta Logo
6:45 pm - 10:23 pmSTL-SNA
5h 38m1 stop
Delta Logo
6:55 pm - 8:36 amSNA-STL
11h 41m2 stops
$325Delta
Find Deal
jue., ago. 28 - mar., sep. 2
United Airlines Logo
11:05 am - 8:28 pmSTL-SNA
11h 23m2 stops
United Airlines Logo
11:32 am - 10:35 pmSNA-STL
9h 03m2 stops
$367United Airlines
Find Deal
mar., sep. 23 - sáb., sep. 27

Spirit Airlines flights from St. Louis to Santa Ana

Our best Spirit Airlines deals on St. Louis to Santa Ana flight tickets
Spirit Airlines
Sep 25
STL12:05 pmLambert-St Louis
25h 30m
1 stop
SNA11:35 amSanta Ana J. Wayne/Orange Cnty
Sep 27
SNA12:32 pmSanta Ana J. Wayne/Orange Cnty
20h 18m
1 stop
STL10:50 amLambert-St Louis
$219
Find similar
Spirit Airlines
Aug 17
STL2:30 pmLambert-St Louis
22h 59m
1 stop
SNA11:29 amSanta Ana J. Wayne/Orange Cnty
Aug 21
SNA12:24 pmSanta Ana J. Wayne/Orange Cnty
23h 08m
1 stop
STL1:32 pmLambert-St Louis
$257
Find similar
Spirit Airlines
Aug 14
STL2:30 pmLambert-St Louis
22h 59m
1 stop
SNA11:29 amSanta Ana J. Wayne/Orange Cnty
Aug 17
SNA12:24 pmSanta Ana J. Wayne/Orange Cnty
23h 08m
1 stop
STL1:32 pmLambert-St Louis
$282
Find similar

Frontier flights from St. Louis to Santa Ana

Our best Frontier deals on St. Louis to Santa Ana flight tickets
Frontier
Sep 2
STL7:54 pmLambert-St Louis
17h 33m
1 stop
SNA11:27 amSanta Ana J. Wayne/Orange Cnty
Sep 6
SNA12:58 pmSanta Ana J. Wayne/Orange Cnty
18h 08m
1 stop
STL9:06 amLambert-St Louis
$225
Find similar
Frontier
Sep 17
STL7:55 pmLambert-St Louis
17h 12m
1 stop
SNA11:07 amSanta Ana J. Wayne/Orange Cnty
Sep 30
SNA12:58 pmSanta Ana J. Wayne/Orange Cnty
18h 08m
1 stop
STL9:06 amLambert-St Louis
$227
Find similar
Frontier
Sep 23
STL7:55 pmLambert-St Louis
18h 18m
1 stop
SNA12:13 pmSanta Ana J. Wayne/Orange Cnty
Sep 27
SNA12:58 pmSanta Ana J. Wayne/Orange Cnty
18h 08m
1 stop
STL9:06 amLambert-St Louis
$228
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated julio 31, 2025.
Use the filters below to find and compare flights from St. Louis to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

jue. 9/25

12:05 pm-11:35 am

1 stop25h 30m

Santa Ana J. Wayne/Orange Cnty

sáb. 9/27

12:32 pm-10:50 am

1 stop20h 18m

$219

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

mar. 9/2

7:54 pm-11:27 am

1 stop17h 33m

Santa Ana J. Wayne/Orange Cnty

sáb. 9/6

12:58 pm-9:06 am

1 stop18h 08m

$225

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

jue. 8/28

7:01 am-11:38 am

1 stop6h 37m

Santa Ana J. Wayne/Orange Cnty

mar. 9/2

10:38 am-10:17 pm

1 stop9h 39m

$267

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

mar. 9/2

7:53 am-11:57 am

1 stop6h 04m

Santa Ana J. Wayne/Orange Cnty

sáb. 9/6

12:50 pm-10:50 pm

2 stops8h 00m

$272

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

dom. 11/2

5:20 am-10:50 am

1 stop7h 30m

Santa Ana J. Wayne/Orange Cnty

sáb. 11/8

7:30 am-5:00 pm

2 stops7h 30m

$277

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

mar. 8/19

5:15 am-9:16 am

1 stop6h 01m

Santa Ana J. Wayne/Orange Cnty

sáb. 8/23

10:30 am-9:32 pm

1 stop9h 02m

$279

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

mar. 9/2

4:35 pm-9:10 pm

1 stop6h 35m

Santa Ana J. Wayne/Orange Cnty

vie. 9/5

6:45 am-6:35 pm

2 stops9h 50m

$282

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

mié. 11/5

2:29 pm-10:17 pm

2 stops9h 48m

Santa Ana J. Wayne/Orange Cnty

lun. 11/10

5:05 pm-12:37 am

1 stop5h 32m

$315

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

jue. 8/28

6:45 pm-10:23 pm

1 stop5h 38m

Santa Ana J. Wayne/Orange Cnty

mar. 9/2

6:55 pm-8:36 am

2 stops11h 41m

$325

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

mar. 9/23

11:05 am-8:28 pm

2 stops11h 23m

Santa Ana J. Wayne/Orange Cnty

sáb. 9/27

11:32 am-10:35 pm

2 stops9h 03m

$367

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from St. Louis to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from St. Louis is in April. Flight prices, which tend to average around $366, are often lower during this time because this is during the off-season. The month of November is another great option to travel to Santa Ana, with average flight prices from St. Louis averaging around $391.

What is the cheapest day to depart on your flight to Santa Ana?

On average, the least expensive day to fly to Santa Ana from St. Louis is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $396. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Tuesday is the most expensive day to depart from St. Louis because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $475.

What is the cheapest time of day to depart on your flight to Santa Ana?

Our data shows that the cheapest St. Louis to Santa Ana flights are usually those with departure times in the evening. Our users have found flights to Santa Ana in the evening for as low as $218. Try not to purchase tickets at noon because they tend to be around $488. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Santa Ana?

You are more likely to see cheaper flights to Santa Ana from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana for around $429 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana from St. Louis for as low as $332 on momondo.

How have St. Louis to Santa Ana flight prices changed over time?

As of July 2025, prices for St. Louis to Santa Ana flights are approximately 35% more expensive when compared to flights at the same time last year.

When to book flights from St. Louis to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Santa Ana (STL to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santa Ana

Best Price Found

$113

Fastest flight time

5h 38m

Direct flights

None

Airports in Santa Ana

1 airport
The best one-way flight to Santa Ana from St. Louis in the past 72 hours is $113. The best round-trip flight deal from St. Louis to Santa Ana found on momondo in the last 72 hours is $219.
The fastest flight from St. Louis to Santa Ana takes 5h 38m
There are no direct flights from St. Louis to Santa Ana. Popular non-direct route for this connection is Lambert-St Louis Airport - Santa Ana J. Wayne/Orange Cnty Airport.
There is 1 airport near Santa Ana: Santa Ana J. Wayne/Orange Cnty (SNA)
Search flight deals

  • How far is Lambert-St Louis to Santa Ana J. Wayne/Orange Cnty by plane?

    Lambert-St Louis and Santa Ana J. Wayne/Orange Cnty are 1572.0 mi apart from one another. A reasonable flight in good conditions will take 5h 38m.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from St. Louis to Santa Ana?

Best airlines flying from St. Louis to Santa Ana

Compare and see reviews for airlines that fly from St. Louis to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $144Free CancellationRating
5.9
3,239 reviews
Search Frontier flights
DeltaPriceFrom $286Free CancellationRating
8.0
7,981 reviews
Search Delta flights
United AirlinesPriceFrom $322Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights
SouthwestPriceFrom $332Free CancellationRating
8.0
4,246 reviews
Search Southwest flights
American AirlinesPriceFrom $342Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

  • Southwest Flights From St. Louis to Santa Ana

    Southwest is one of the most popular airlines flying from St. Louis to Santa Ana, operating 2 flights/week on average for this route. A good Southwest flight deal for St. Louis to Santa Ana starts from $332 round-trip, up to an average price of $452. Our users have rated Southwest at 8.0/10.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from St. Louis to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from St. Louis to Santa Ana with flexible booking policies on momondo?

All flight searches from St. Louis to Santa Ana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from St. Louis to Santa Ana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Ana from St. Louis.

I’m not ready to book a flight from St. Louis to Santa Ana right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santa Ana from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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