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Cheap flights from St. Louis to Los Angeles from $111

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Los Angeles departing on 5/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:08 pm - 9:09 am
STL
-
SNA
15h 01m
1 stop
Frontier Logo
9:54 am - 7:23 pm
SNA
-
STL
7h 29m
1 stop
$210Frontier
Fri, May 8 - Mon, May 11
Frontier Logo
9:55 pm - 6:11 pm
STL
-
SNA
22h 16m
1 stop
Frontier Logo
11:32 am - 7:12 pm
SNA
-
STL
5h 40m
1 stop
$221Frontier
Thu, May 7 - Mon, May 11
Frontier Logo
9:55 pm - 5:56 pm
STL
-
SNA
22h 01m
1 stop
Frontier Logo
7:56 pm - 11:22 am
SNA
-
STL
13h 26m
1 stop
$251Frontier
Sun, Apr 26 - Thu, Apr 30
Frontier Logo
10:12 pm - 7:40 pm
STL
-
SNA
23h 28m
1 stop
Frontier Logo
6:22 pm - 11:27 am
SNA
-
STL
15h 05m
1 stop
$260Frontier
Sun, Apr 5 - Thu, Apr 9
Frontier Logo
8:06 pm - 10:44 am
STL
-
SNA
16h 38m
1 stop
Frontier Logo
11:11 am - 5:36 pm
SNA
-
STL
28h 25m
2 stops
$270Frontier
Thu, Apr 23 - Mon, May 4
Frontier Logo
4:19 pm - 3:35 pm
STL
-
SNA
25h 16m
2 stops
Frontier Logo
9:54 am - 7:23 pm
SNA
-
STL
7h 29m
1 stop
$278Frontier
Thu, May 7 - Mon, May 11
Frontier Logo
8:06 pm - 11:25 am
STL
-
SNA
17h 19m
1 stop
Frontier Logo
8:14 pm - 8:23 pm
SNA
-
STL
22h 09m
1 stop
$281Frontier
Fri, May 1 - Fri, May 15
Multiple Airlines Logo
8:41 am - 9:53 am
STL
-
SNA
27h 12m
2 stops
Multiple Airlines Logo
3:23 pm - 9:00 pm
SNA
-
STL
27h 37m
1 stop
$290Multiple Airlines
Fri, Apr 10 - Wed, Apr 15
Frontier Logo
8:17 pm - 10:44 am
STL
-
SNA
16h 27m
1 stop
Frontier Logo
2:39 pm - 6:50 am
SNA
-
STL
38h 11m
2 stops
$292Frontier
Sat, Apr 18 - Sat, Apr 25
Frontier Logo
8:12 pm - 10:46 am
STL
-
SNA
16h 34m
1 stop
Frontier Logo
2:41 pm - 11:19 pm
SNA
-
STL
30h 38m
2 stops
$296Frontier
Thu, May 7 - Mon, May 11

Frontier flights from St. Louis to Santa Ana

Our best Frontier deals on St. Louis to Santa Ana flight tickets
Frontier
May 8
STL8:08 pmLambert-St Louis
15h 01m
1 stop
SNA9:09 amSanta Ana J. Wayne/Orange Cnty
May 11
SNA9:54 amSanta Ana J. Wayne/Orange Cnty
7h 29m
1 stop
STL7:23 pmLambert-St Louis
$210
Frontier
May 7
STL9:55 pmLambert-St Louis
22h 16m
1 stop
SNA6:11 pmSanta Ana J. Wayne/Orange Cnty
May 11
SNA11:32 amSanta Ana J. Wayne/Orange Cnty
5h 40m
1 stop
STL7:12 pmLambert-St Louis
$221
Frontier
Apr 26
STL9:55 pmLambert-St Louis
22h 01m
1 stop
SNA5:56 pmSanta Ana J. Wayne/Orange Cnty
Apr 30
SNA7:56 pmSanta Ana J. Wayne/Orange Cnty
13h 26m
1 stop
STL11:22 amLambert-St Louis
$251

Delta flights from St. Louis to Santa Ana

Our best Delta deals on St. Louis to Santa Ana flight tickets
Delta
May 5
STL2:20 pmLambert-St Louis
10h 08m
2 stops
SNA10:28 pmSanta Ana J. Wayne/Orange Cnty
May 9
SNA1:50 pmSanta Ana J. Wayne/Orange Cnty
8h 09m
1 stop
STL11:59 pmLambert-St Louis
$346
Delta
May 5
STL2:20 pmLambert-St Louis
10h 08m
2 stops
SNA10:28 pmSanta Ana J. Wayne/Orange Cnty
May 9
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 15m
1 stop
STL6:00 pmLambert-St Louis
$362
Delta
Apr 9
STL7:15 amLambert-St Louis
7h 05m
1 stop
SNA12:20 pmSanta Ana J. Wayne/Orange Cnty
Apr 14
SNA5:02 pmSanta Ana J. Wayne/Orange Cnty
5h 23m
1 stop
STL12:25 amLambert-St Louis
$365

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from St. Louis to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 5/8

8:08 pm-9:09 am

1 stop15h 01m

Santa Ana J. Wayne/Orange Cnty

Mon 5/11

9:54 am-7:23 pm

1 stop7h 29m

$210

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 5/7

9:55 pm-6:11 pm

1 stop22h 16m

Santa Ana J. Wayne/Orange Cnty

Mon 5/11

11:32 am-7:12 pm

1 stop5h 40m

$221

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sun 4/26

9:55 pm-5:56 pm

1 stop22h 01m

Santa Ana J. Wayne/Orange Cnty

Thu 4/30

7:56 pm-11:22 am

1 stop13h 26m

$251

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sun 4/5

10:12 pm-7:40 pm

1 stop23h 28m

Santa Ana J. Wayne/Orange Cnty

Thu 4/9

6:22 pm-11:27 am

1 stop15h 05m

$260

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 4/23

8:06 pm-10:44 am

1 stop16h 38m

Santa Ana J. Wayne/Orange Cnty

Mon 5/4

11:11 am-5:36 pm

2 stops28h 25m

$270

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 5/7

4:19 pm-3:35 pm

2 stops25h 16m

Santa Ana J. Wayne/Orange Cnty

Mon 5/11

9:54 am-7:23 pm

1 stop7h 29m

$278

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 5/1

8:06 pm-11:25 am

1 stop17h 19m

Santa Ana J. Wayne/Orange Cnty

Fri 5/15

8:14 pm-8:23 pm

1 stop22h 09m

$281

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 4/10

8:41 am-9:53 am

2 stops27h 12m

Santa Ana J. Wayne/Orange Cnty

Wed 4/15

3:23 pm-9:00 pm

1 stop27h 37m

$290

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sat 4/18

8:17 pm-10:44 am

1 stop16h 27m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

2:39 pm-6:50 am

2 stops38h 11m

$292

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 5/7

8:12 pm-10:46 am

1 stop16h 34m

Santa Ana J. Wayne/Orange Cnty

Mon 5/11

2:41 pm-11:19 pm

2 stops30h 38m

$296

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from St. Louis to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from St. Louis is in November. Flight prices, which tend to average around $345, are often lower during this time because this is during the off-season. The month of April is another great option to travel to Santa Ana, with average flight prices from St. Louis averaging around $362.

How far in advance should I book a flight to Santa Ana?

You are more likely to see cheaper flights to Santa Ana from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana for around $429 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana from St. Louis for as low as $275 on momondo.

How have St. Louis to Santa Ana flight prices changed over time?

As of March 2026, prices for St. Louis to Santa Ana flights are approximately 10% more expensive when compared to flights at the same time last year.

When to book flights from St. Louis to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Santa Ana (STL to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santa Ana

Fastest flight time

5h 05m

Direct flights

None
The fastest flight from St. Louis to Santa Ana takes 5h 05m
There are no direct flights from St. Louis to Santa Ana. There are no popular flight routes from St. Louis to Santa Ana.
Search flight deals

  • How far is Lambert-St Louis to Santa Ana J. Wayne/Orange Cnty by plane?

    Lambert-St Louis and Santa Ana J. Wayne/Orange Cnty are 1572.0 mi apart from one another. A reasonable flight in good conditions will take 5h 05m.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from St. Louis to Santa Ana?

Best airlines flying from St. Louis to Santa Ana

Compare and see reviews for airlines that fly from St. Louis to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $126Free CancellationRating
5.7
3,032 reviews
Search Frontier flights
American AirlinesPriceFrom $278Free CancellationRating
7.1
11,472 reviews
Search American Airlines flights
United AirlinesPriceFrom $286Free CancellationRating
7.4
9,428 reviews
Search United Airlines flights
SouthwestPriceFrom $316Free CancellationRating
8.0
4,318 reviews
Search Southwest flights

  • United Airlines Flights From St. Louis to Santa Ana

    United Airlines is one of the most popular airlines flying from St. Louis to Santa Ana, operating 4 flights/week on average for this route. A good United Airlines flight deal for St. Louis to Santa Ana starts from $286 round-trip, up to an average price of $513. Our users have rated United Airlines at 7.4/10.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from St. Louis to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from St. Louis to Santa Ana with flexible booking policies on momondo?

All flight searches from St. Louis to Santa Ana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from St. Louis to Santa Ana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Ana from St. Louis.

I’m not ready to book a flight from St. Louis to Santa Ana right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santa Ana from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Santa Ana trip

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