Cheap flights from St. Louis to Los Angeles from $63

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Los Angeles departing on 11/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Multiple Airlines Logo
7:52 pm - 1:35 pmSTL-SNA
19h 43m1 stop
Multiple Airlines Logo
6:45 am - 5:27 pmSNA-STL
8h 42m2 stops
$205Multiple Airlines
Find Deal
Mon, Oct 27 - Thu, Oct 30
Frontier Logo
8:40 pm - 1:35 pmSTL-SNA
18h 55m1 stop
Frontier Logo
12:01 pm - 9:07 amSNA-STL
19h 06m1 stop
$213Frontier
Find Deal
Fri, Oct 31 - Mon, Nov 3
American Airlines Logo
11:55 am - 6:01 pmSTL-SNA
8h 06m1 stop
American Airlines Logo
10:58 am - 6:19 pmSNA-STL
5h 21m1 stop
$315American Airlines
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Wed, Feb 11 - Sat, Feb 14
Delta Logo
7:00 am - 4:32 pmSTL-SNA
11h 32m2 stops
Delta Logo
7:15 am - 9:37 pmSNA-STL
12h 22m2 stops
$316Delta
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Tue, Jan 6 - Mon, Jan 12
Delta Logo
7:00 am - 6:17 pmSTL-SNA
13h 17m2 stops
Delta Logo
7:15 am - 9:42 pmSNA-STL
12h 27m2 stops
$326Delta
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Wed, Feb 11 - Sat, Feb 14
American Airlines Logo
5:17 am - 9:53 amSTL-SNA
6h 36m1 stop
American Airlines Logo
10:43 am - 7:29 pmSNA-STL
6h 46m1 stop
$335American Airlines
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Tue, Dec 2 - Tue, Dec 9
Southwest Logo
5:00 am - 11:30 amSTL-SNA
8h 30m1 stop
Southwest Logo
5:30 pm - 12:30 amSNA-STL
5h 00m1 stop
$354Southwest
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Wed, Dec 17 - Mon, Dec 22
Southwest Logo
5:30 am - 9:35 amSTL-SNA
6h 05m1 stop
Southwest Logo
5:30 pm - 12:30 amSNA-STL
5h 00m1 stop
$363Southwest
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Mon, Nov 24 - Tue, Nov 25
United Airlines Logo
2:45 pm - 9:18 pmSTL-SNA
8h 33m1 stop
United Airlines Logo
8:40 am - 4:34 pmSNA-STL
5h 54m1 stop
$405United Airlines
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Wed, Feb 11 - Sat, Feb 14
United Airlines Logo
9:00 am - 6:47 pmSTL-SNA
11h 47m2 stops
United Airlines Logo
7:50 pm - 10:46 amSNA-STL
12h 56m2 stops
$433United Airlines
Find Deal
Tue, Dec 9 - Sat, Dec 13

Delta flights from St. Louis to Santa Ana, California

Our best Delta deals on St. Louis to Santa Ana, California flight tickets
Delta
Jan 6
STL7:00 amLambert-St Louis
11h 32m
2 stops
SNA4:32 pmSanta Ana J. Wayne/Orange Cnty
Jan 12
SNA7:15 amSanta Ana J. Wayne/Orange Cnty
12h 22m
2 stops
STL9:37 pmLambert-St Louis
Delta
Feb 11
STL7:00 amLambert-St Louis
13h 17m
2 stops
SNA6:17 pmSanta Ana J. Wayne/Orange Cnty
Feb 14
SNA7:15 amSanta Ana J. Wayne/Orange Cnty
12h 27m
2 stops
STL9:42 pmLambert-St Louis
Delta
Dec 9
STL1:59 pmLambert-St Louis
10h 21m
1 stop
SNA10:20 pmSanta Ana J. Wayne/Orange Cnty
Dec 13
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
7h 23m
1 stop
STL4:08 pmLambert-St Louis

Alaska Airlines flights from St. Louis to Santa Ana, California

Our best Alaska Airlines deals on St. Louis to Santa Ana, California flight tickets
Alaska Airlines
Feb 1
STL2:50 pmLambert-St Louis
9h 40m
1 stop
SNA10:30 pmSanta Ana J. Wayne/Orange Cnty
Feb 12
SNA11:15 amSanta Ana J. Wayne/Orange Cnty
10h 41m
1 stop
STL11:56 pmLambert-St Louis
Alaska Airlines
Feb 22
STL2:55 pmLambert-St Louis
9h 35m
1 stop
SNA10:30 pmSanta Ana J. Wayne/Orange Cnty
Feb 26
SNA11:15 amSanta Ana J. Wayne/Orange Cnty
10h 41m
1 stop
STL11:56 pmLambert-St Louis
Alaska Airlines
Feb 11
STL2:50 pmLambert-St Louis
23h 09m
2 stops
SNA11:59 amSanta Ana J. Wayne/Orange Cnty
Feb 14
SNA12:40 pmSanta Ana J. Wayne/Orange Cnty
9h 16m
1 stop
STL11:56 pmLambert-St Louis

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from St. Louis to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 10/27

7:52 pm-1:35 pm

1 stop19h 43m

Santa Ana J. Wayne/Orange Cnty

Thu 10/30

6:45 am-5:27 pm

2 stops8h 42m

$205

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 10/31

8:40 pm-1:35 pm

1 stop18h 55m

Santa Ana J. Wayne/Orange Cnty

Mon 11/3

12:01 pm-9:07 am

1 stop19h 06m

$213

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 2/11

11:55 am-6:01 pm

1 stop8h 06m

Santa Ana J. Wayne/Orange Cnty

Sat 2/14

10:58 am-6:19 pm

1 stop5h 21m

$315

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Tue 1/6

7:00 am-4:32 pm

2 stops11h 32m

Santa Ana J. Wayne/Orange Cnty

Mon 1/12

7:15 am-9:37 pm

2 stops12h 22m

$316

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 2/11

7:00 am-6:17 pm

2 stops13h 17m

Santa Ana J. Wayne/Orange Cnty

Sat 2/14

7:15 am-9:42 pm

2 stops12h 27m

$326

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Tue 12/2

5:17 am-9:53 am

1 stop6h 36m

Santa Ana J. Wayne/Orange Cnty

Tue 12/9

10:43 am-7:29 pm

1 stop6h 46m

$335

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 12/17

5:00 am-11:30 am

1 stop8h 30m

Santa Ana J. Wayne/Orange Cnty

Mon 12/22

5:30 pm-12:30 am

1 stop5h 00m

$354

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 11/24

5:30 am-9:35 am

1 stop6h 05m

Santa Ana J. Wayne/Orange Cnty

Tue 11/25

5:30 pm-12:30 am

1 stop5h 00m

$363

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 2/11

2:45 pm-9:18 pm

1 stop8h 33m

Santa Ana J. Wayne/Orange Cnty

Sat 2/14

8:40 am-4:34 pm

1 stop5h 54m

$405

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Tue 12/9

9:00 am-6:47 pm

2 stops11h 47m

Santa Ana J. Wayne/Orange Cnty

Sat 12/13

7:50 pm-10:46 am

2 stops12h 56m

$433

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from St. Louis to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, April is the cheapest month to fly from St. Louis to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $366. If you aren’t able to travel during the month of April, then book flights to Santa Ana, California from St. Louis during November instead. Flights to Santa Ana, California in November, while not as cheap as those in April, still average around $384.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from St. Louis to Santa Ana, California is on a Wednesday. Travelers who choose to depart for Santa Ana, California on a Wednesday will often find tickets for as low as $396. The most expensive day to fly to Santa Ana, California is Tuesday, with ticket prices averaging around $475.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the evening is the cheapest time of day to fly from St. Louis to Santa Ana, California when you can find flight prices for as low as $218. Flying to Santa Ana, California in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is at noon when prices are around $488.

How far in advance should I book a flight to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $434 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from St. Louis for as low as $306 on momondo.

How have St. Louis to Santa Ana, California flight prices changed over time?

As of October 2025, prices for St. Louis to Santa Ana, California flights are approximately 22% cheaper when compared to flights at the same time last year.

When to book flights from St. Louis to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Santa Ana, California (STL to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santa Ana, California

Direct flights

None
There are no direct flights from St. Louis to Santa Ana, California. There are no popular flight routes from St. Louis to Santa Ana, California.
  • How far is Lambert-St Louis to Santa Ana J. Wayne/Orange Cnty by plane?

    Lambert-St Louis and Santa Ana J. Wayne/Orange Cnty are 1572.0 mi apart from one another. A reasonable flight in good conditions will take 5h 40m.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from St. Louis to Santa Ana, California?

Best airlines flying from St. Louis to Santa Ana, California

Compare and see reviews for airlines that fly from St. Louis to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $144Free CancellationRating
5.8
3,137 reviews
Search Frontier flights
DeltaPriceFrom $277Free CancellationRating
7.9
7,984 reviews
Search Delta flights
American AirlinesPriceFrom $296Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights
United AirlinesPriceFrom $322Free CancellationRating
7.4
8,982 reviews
Search United Airlines flights
SouthwestPriceFrom $332Free CancellationRating
8.0
4,241 reviews
Search Southwest flights
  • Southwest Flights From St. Louis to Santa Ana, California

    Southwest is one of the most popular airlines flying from St. Louis to Santa Ana, California, operating 3 flights/week on average for this route. A good Southwest flight deal for St. Louis to Santa Ana, California starts from $332 round-trip, up to an average price of $446. Our users have rated Southwest at 8.0/10.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from St. Louis to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from St. Louis to Santa Ana with flexible booking policies on momondo?

All flight searches from St. Louis to Santa Ana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from St. Louis to Santa Ana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Ana from St. Louis.

I’m not ready to book a flight from St. Louis to Santa Ana right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santa Ana from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Sat 11/15
Sat 11/22

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