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Cheap flights from St. Louis to Los Angeles from $145

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Los Angeles departing on 9/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:10 pm - 10:11 am-
16h 01m
Frontier Logo
11:06 am - 7:15 pm-
6h 09m
$228Frontier
Thu, Oct 29 - Sun, Nov 1
Frontier Logo
8:10 pm - 10:11 am-
16h 01m
Frontier Logo
11:06 am - 7:15 pm-
6h 09m
$251Frontier
Thu, Nov 5 - Sun, Nov 8
Multiple Airlines Logo
1:02 pm - 11:05 am-
24h 03m
Multiple Airlines Logo
7:30 am - 11:32 am-
26h 02m
$278Multiple Airlines
Sun, Sep 13 - Tue, Sep 15
Multiple Airlines Logo
8:10 pm - 10:11 am-
16h 01m
Multiple Airlines Logo
7:30 am - 10:39 pm-
13h 09m
$279Multiple Airlines
Thu, Nov 5 - Tue, Nov 10
American Airlines Logo
9:36 am - 3:49 pm-
8h 13m
American Airlines Logo
7:00 am - 2:47 pm-
5h 47m
$375American Airlines
Tue, Jan 5 - Sat, Jan 9
American Airlines Logo
8:36 am - 12:42 pm-
6h 06m
American Airlines Logo
2:29 pm - 11:42 pm-
7h 13m
$375American Airlines
Mon, Aug 24 - Tue, Sep 1
Southwest Logo
5:30 pm - 9:45 pm-
6h 15m
Southwest Logo
6:45 am - 4:05 pm-
7h 20m
$380Southwest
Tue, Jan 5 - Sat, Jan 9
Southwest Logo
8:35 am - 2:40 pm-
8h 05m
Southwest Logo
3:40 pm - 10:50 pm-
5h 10m
$385Southwest
Wed, Sep 9 - Wed, Sep 9
United Airlines Logo
5:30 pm - 10:25 pm-
6h 55m
United Airlines Logo
6:45 am - 3:43 pm-
6h 58m
$407United Airlines
Tue, Sep 8 - Sat, Sep 12
United Airlines Logo
1:30 pm - 5:31 pm-
6h 01m
United Airlines Logo
1:20 pm - 8:59 pm-
5h 39m
$451United Airlines
Wed, Jan 13 - Fri, Jan 15

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Frontier flights from St. Louis to Santa Ana, California

Our best Frontier deals on St. Louis to Santa Ana, California flight tickets
Frontier
Oct 29
STL8:10 pmLambert-St Louis
16h 01m
1 stop
SNA10:11 amSanta Ana J. Wayne/Orange Cnty
Nov 1
SNA11:06 amSanta Ana J. Wayne/Orange Cnty
6h 09m
1 stop
STL7:15 pmLambert-St Louis
$228
Frontier
Nov 5
STL8:10 pmLambert-St Louis
16h 01m
1 stop
SNA10:11 amSanta Ana J. Wayne/Orange Cnty
Nov 8
SNA11:06 amSanta Ana J. Wayne/Orange Cnty
6h 09m
1 stop
STL7:15 pmLambert-St Louis
$251
Frontier
Nov 5
STL8:10 pmLambert-St Louis
16h 01m
1 stop
SNA10:11 amSanta Ana J. Wayne/Orange Cnty
Nov 8
SNA11:06 amSanta Ana J. Wayne/Orange Cnty
6h 09m
1 stop
STL7:15 pmLambert-St Louis
$261

Alaska Airlines flights from St. Louis to Santa Ana, California

Our best Alaska Airlines deals on St. Louis to Santa Ana, California flight tickets
Alaska Airlines
Aug 12
STL6:02 amLambert-St Louis
9h 53m
1 stop
SNA1:55 pmSanta Ana J. Wayne/Orange Cnty
Aug 17
SNA2:45 pmSanta Ana J. Wayne/Orange Cnty
21h 07m
1 stop
STL1:52 pmLambert-St Louis
$807
Alaska Airlines
Aug 12
STL7:56 pmLambert-St Louis
17h 53m
2 stops
SNA11:49 amSanta Ana J. Wayne/Orange Cnty
Aug 17
SNA6:47 amSanta Ana J. Wayne/Orange Cnty
10h 10m
1 stop
STL6:57 pmLambert-St Louis
$841
Alaska Airlines
Aug 13
STL7:56 pmLambert-St Louis
15h 30m
1 stop
SNA9:26 amSanta Ana J. Wayne/Orange Cnty
Aug 16
SNA8:25 pmSanta Ana J. Wayne/Orange Cnty
20h 32m
2 stops
STL6:57 pmLambert-St Louis
$1,026

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from St. Louis to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 10/29

8:10 pm-10:11 am

1 stop16h 01m

Santa Ana J. Wayne/Orange Cnty

Sun 11/1

11:06 am-7:15 pm

1 stop6h 09m

$228

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 11/5

8:10 pm-10:11 am

1 stop16h 01m

Santa Ana J. Wayne/Orange Cnty

Sun 11/8

11:06 am-7:15 pm

1 stop6h 09m

$251

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sun 9/13

1:02 pm-11:05 am

1 stop24h 03m

Santa Ana J. Wayne/Orange Cnty

Tue 9/15

7:30 am-11:32 am

1 stop26h 02m

$278

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 11/5

8:10 pm-10:11 am

1 stop16h 01m

Santa Ana J. Wayne/Orange Cnty

Tue 11/10

7:30 am-10:39 pm

1 stop13h 09m

$279

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Tue 1/5

9:36 am-3:49 pm

1 stop8h 13m

Santa Ana J. Wayne/Orange Cnty

Sat 1/9

7:00 am-2:47 pm

1 stop5h 47m

$375

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 8/24

8:36 am-12:42 pm

1 stop6h 06m

Santa Ana J. Wayne/Orange Cnty

Tue 9/1

2:29 pm-11:42 pm

1 stop7h 13m

$375

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Tue 1/5

5:30 pm-9:45 pm

1 stop6h 15m

Santa Ana J. Wayne/Orange Cnty

Sat 1/9

6:45 am-4:05 pm

2 stops7h 20m

$380

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 9/9

8:35 am-2:40 pm

1 stop8h 05m

Santa Ana J. Wayne/Orange Cnty

Wed 9/9

3:40 pm-10:50 pm

1 stop5h 10m

$385

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Tue 9/8

5:30 pm-10:25 pm

1 stop6h 55m

Santa Ana J. Wayne/Orange Cnty

Sat 9/12

6:45 am-3:43 pm

1 stop6h 58m

$407
Quickest round-trip

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 1/13

1:30 pm-5:31 pm

1 stop6h 01m

Santa Ana J. Wayne/Orange Cnty

Fri 1/15

1:20 pm-8:59 pm

1 stop5h 39m

$451

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from St. Louis to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between St. Louis and Santa Ana, California?

Prices are currently low for flights on this route.

Typical prices usually range from $377 to $592.
The lowest price recently found on this route was $228.

What is the cheapest month to fly to Santa Ana, California?

In general, November is the cheapest month to fly from St. Louis to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $332. If you aren’t able to travel during the month of November, then book flights to Santa Ana, California from St. Louis during April instead. Flights to Santa Ana, California in April, while not as cheap as those in November, still average around $349.

How far in advance should I book a flight from St. Louis to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $464 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from St. Louis for as low as $300 on momondo.

How have St. Louis to Santa Ana, California flight prices changed over time?

As of August 2026, prices for St. Louis to Santa Ana, California flights are approximately 247% more expensive when compared to flights at the same time last year.

When to book flights from St. Louis to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Santa Ana, California (STL to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santa Ana, California

Fastest flight time

5h 40m

Direct flights

None
The fastest flight from St. Louis to Santa Ana, California takes 5h 40m
There are no direct flights from St. Louis to Santa Ana, California. There are no popular flight routes from St. Louis to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from St. Louis to Santa Ana, California

  • How far is Lambert-St Louis to Santa Ana J. Wayne/Orange Cnty by plane?

    Lambert-St Louis and Santa Ana J. Wayne/Orange Cnty are 1572.0 mi apart from one another. A reasonable flight in good conditions will take 5h 40m.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from St. Louis to Santa Ana, California?

Best airlines flying from St. Louis to Santa Ana, California

Compare and see reviews for airlines that fly from St. Louis to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $159Free CancellationRating
5.6
2,736 reviews
Search Frontier flights
American AirlinesPriceFrom $296Free CancellationRating
7.1
11,845 reviews
Search American Airlines flights
SouthwestPriceFrom $332Free CancellationRating
8.0
4,221 reviews
Search Southwest flights
United AirlinesPriceFrom $332Free CancellationRating
7.4
10,060 reviews
Search United Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from St. Louis to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from St. Louis to Santa Ana with flexible booking policies on momondo?

All flight searches from St. Louis to Santa Ana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from St. Louis to Santa Ana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Ana from St. Louis.

I’m not ready to book a flight from St. Louis to Santa Ana right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santa Ana from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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