Cheap flights from St. Louis to Los Angeles from $98

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Los Angeles departing on 1/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:46 pm - 12:25 pm
STL
-
SNA
16h 39m1 stop
Multiple Airlines Logo
12:12 pm - 2:48 pm
SNA
-
STL
24h 36m1 stop
$158Multiple Airlines
Sun, Jan 11 - Fri, Jan 16
Frontier Logo
1:07 pm - 7:18 pm
STL
-
SNA
8h 11m1 stop
Frontier Logo
10:30 am - 8:08 pm
SNA
-
STL
7h 38m1 stop
$195Frontier
Mon, Jan 12 - Mon, Jan 19
Multiple Airlines Logo
9:46 pm - 2:11 pm
STL
-
SNA
18h 25m2 stops
Multiple Airlines Logo
6:45 am - 9:14 pm
SNA
-
STL
12h 29m1 stop
$198Multiple Airlines
Sun, Jan 11 - Fri, Jan 16
Multiple Airlines Logo
1:07 pm - 8:57 pm
STL
-
SNA
9h 50m1 stop
Multiple Airlines Logo
5:31 pm - 2:46 pm
SNA
-
STL
43h 15m2 stops
$209Multiple Airlines
Mon, Jan 12 - Mon, Jan 19
Frontier Logo
7:43 pm - 10:52 am
STL
-
SNA
17h 09m1 stop
Frontier Logo
4:16 pm - 12:12 pm
SNA
-
STL
17h 56m1 stop
$218Frontier
Wed, Jan 7 - Sun, Jan 11
Frontier Logo
3:43 pm - 10:43 am
STL
-
SNA
21h 00m1 stop
Frontier Logo
10:30 am - 8:08 pm
SNA
-
STL
7h 38m1 stop
$221Frontier
Sat, Jan 17 - Mon, Jan 19
Multiple Airlines Logo
1:07 pm - 6:50 pm
STL
-
SNA
7h 43m1 stop
Multiple Airlines Logo
1:20 pm - 9:21 pm
SNA
-
STL
6h 01m1 stop
$239Multiple Airlines
Thu, Jan 8 - Fri, Jan 9
Frontier Logo
10:16 pm - 3:48 pm
STL
-
SNA
19h 32m1 stop
Frontier Logo
4:16 pm - 12:12 pm
SNA
-
STL
17h 56m1 stop
$253Frontier
Fri, Jan 9 - Sun, Jan 11
Frontier Logo
1:07 pm - 6:50 pm
STL
-
SNA
7h 43m1 stop
Frontier Logo
8:14 pm - 10:02 am
SNA
-
STL
11h 48m2 stops
$280Frontier
Thu, Jan 8 - Fri, Jan 9
Frontier Logo
10:10 pm - 7:12 pm
STL
-
SNA
23h 02m1 stop
Frontier Logo
4:43 pm - 11:39 am
SNA
-
STL
16h 56m1 stop
$283Frontier
Sat, Jan 3 - Sat, Jan 10

Alaska Airlines flights from St. Louis to Santa Ana, California

Our best Alaska Airlines deals on St. Louis to Santa Ana, California flight tickets
Alaska Airlines
Jan 8
STL2:50 pmLambert-St Louis
8h 37m
1 stop
SNA9:27 pmSanta Ana J. Wayne/Orange Cnty
Jan 12
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
29h 09m
1 stop
STL1:54 pmLambert-St Louis
Alaska Airlines
Jan 5
STL5:26 pmLambert-St Louis
18h 38m
1 stop
SNA10:04 amSanta Ana J. Wayne/Orange Cnty
Jan 12
SNA8:48 pmSanta Ana J. Wayne/Orange Cnty
15h 06m
1 stop
STL1:54 pmLambert-St Louis
Alaska Airlines
Jan 5
STL5:26 pmLambert-St Louis
18h 38m
1 stop
SNA10:04 amSanta Ana J. Wayne/Orange Cnty
Jan 12
SNA2:20 pmSanta Ana J. Wayne/Orange Cnty
21h 34m
2 stops
STL1:54 pmLambert-St Louis

Delta flights from St. Louis to Santa Ana, California

Our best Delta deals on St. Louis to Santa Ana, California flight tickets
Delta
Mar 18
STL7:15 amLambert-St Louis
13h 08m
2 stops
SNA6:23 pmSanta Ana J. Wayne/Orange Cnty
Mar 24
SNA11:37 amSanta Ana J. Wayne/Orange Cnty
9h 38m
2 stops
STL11:15 pmLambert-St Louis
Delta
Jan 8
STL3:45 pmLambert-St Louis
8h 30m
1 stop
SNA10:15 pmSanta Ana J. Wayne/Orange Cnty
Jan 12
SNA7:30 amSanta Ana J. Wayne/Orange Cnty
12h 05m
2 stops
STL9:35 pmLambert-St Louis
Delta
Mar 18
STL6:04 pmLambert-St Louis
5h 55m
1 stop
SNA9:59 pmSanta Ana J. Wayne/Orange Cnty
Mar 24
SNA11:37 amSanta Ana J. Wayne/Orange Cnty
9h 38m
2 stops
STL11:15 pmLambert-St Louis

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from St. Louis to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sun 1/11

9:46 pm-12:25 pm

1 stop16h 39m

Santa Ana J. Wayne/Orange Cnty

Fri 1/16

12:12 pm-2:48 pm

1 stop24h 36m

$158

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 1/12

1:07 pm-7:18 pm

1 stop8h 11m

Santa Ana J. Wayne/Orange Cnty

Mon 1/19

10:30 am-8:08 pm

1 stop7h 38m

$195

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sun 1/11

9:46 pm-2:11 pm

2 stops18h 25m

Santa Ana J. Wayne/Orange Cnty

Fri 1/16

6:45 am-9:14 pm

1 stop12h 29m

$198

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 1/12

1:07 pm-8:57 pm

1 stop9h 50m

Santa Ana J. Wayne/Orange Cnty

Mon 1/19

5:31 pm-2:46 pm

2 stops43h 15m

$209

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 1/7

7:43 pm-10:52 am

1 stop17h 09m

Santa Ana J. Wayne/Orange Cnty

Sun 1/11

4:16 pm-12:12 pm

1 stop17h 56m

$218

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sat 1/17

3:43 pm-10:43 am

1 stop21h 00m

Santa Ana J. Wayne/Orange Cnty

Mon 1/19

10:30 am-8:08 pm

1 stop7h 38m

$221

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 1/8

1:07 pm-6:50 pm

1 stop7h 43m

Santa Ana J. Wayne/Orange Cnty

Fri 1/9

1:20 pm-9:21 pm

1 stop6h 01m

$239

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 1/9

10:16 pm-3:48 pm

1 stop19h 32m

Santa Ana J. Wayne/Orange Cnty

Sun 1/11

4:16 pm-12:12 pm

1 stop17h 56m

$253

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 1/8

1:07 pm-6:50 pm

1 stop7h 43m

Santa Ana J. Wayne/Orange Cnty

Fri 1/9

8:14 pm-10:02 am

2 stops11h 48m

$280

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Sat 1/3

10:10 pm-7:12 pm

1 stop23h 02m

Santa Ana J. Wayne/Orange Cnty

Sat 1/10

4:43 pm-11:39 am

1 stop16h 56m

$283

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from St. Louis to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between St. Louis and Santa Ana, California?

What is the cheapest month to fly to Santa Ana, California?

In general, November is the cheapest month to fly from St. Louis to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $345. If you aren’t able to travel during the month of November, then book flights to Santa Ana, California from St. Louis during April instead. Flights to Santa Ana, California in April, while not as cheap as those in November, still average around $366.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from St. Louis to Santa Ana, California is on a Wednesday. Travelers who choose to depart for Santa Ana, California on a Wednesday will often find tickets for as low as $396. The most expensive day to fly to Santa Ana, California is Tuesday, with ticket prices averaging around $475.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the evening is the cheapest time of day to fly from St. Louis to Santa Ana, California when you can find flight prices for as low as $218. Flying to Santa Ana, California in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is at noon when prices are around $488.

How far in advance should I book a flight to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $436 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from St. Louis for as low as $302 on momondo.

How have St. Louis to Santa Ana, California flight prices changed over time?

As of December 2025, prices for St. Louis to Santa Ana, California flights are approximately 10% more expensive when compared to flights at the same time last year.

When to book flights from St. Louis to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Santa Ana, California (STL to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santa Ana, California

Fastest flight time

5h 35m

Direct flights

None
The fastest flight from St. Louis to Santa Ana, California takes 5h 35m
There are no direct flights from St. Louis to Santa Ana, California. There are no popular flight routes from St. Louis to Santa Ana, California.
  • How far is Lambert-St Louis to Santa Ana J. Wayne/Orange Cnty by plane?

    Lambert-St Louis and Santa Ana J. Wayne/Orange Cnty are 1572.0 mi apart from one another. A reasonable flight in good conditions will take 5h 35m.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from St. Louis to Santa Ana, California?

Best airlines flying from St. Louis to Santa Ana, California

Compare and see reviews for airlines that fly from St. Louis to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $126Free CancellationRating
5.8
3,080 reviews
Search Frontier flights
DeltaPriceFrom $277Free CancellationRating
7.9
8,008 reviews
Search Delta flights
American AirlinesPriceFrom $294Free CancellationRating
7.2
11,052 reviews
Search American Airlines flights
United AirlinesPriceFrom $322Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights
SouthwestPriceFrom $332Free CancellationRating
7.9
4,250 reviews
Search Southwest flights
  • Southwest Flights From St. Louis to Santa Ana, California

    Southwest is one of the most popular airlines flying from St. Louis to Santa Ana, California, operating 3 flights/week on average for this route. A good Southwest flight deal for St. Louis to Santa Ana, California starts from $332 round-trip, up to an average price of $446. Our users have rated Southwest at 7.9/10.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from St. Louis to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from St. Louis to Santa Ana with flexible booking policies on momondo?

All flight searches from St. Louis to Santa Ana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from St. Louis to Santa Ana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Ana from St. Louis.

I’m not ready to book a flight from St. Louis to Santa Ana right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santa Ana from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Wed 1/14
Wed 1/21

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