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Cheap flights from St. Louis to Los Angeles from $93

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Los Angeles departing on 2/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from St. Louis to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:14 pm - 8:57 pm
STL
-
SNA
10h 43m
1 stop
Multiple Airlines Logo
1:20 pm - 11:19 am
SNA
-
STL
19h 59m
1 stop
$197Multiple Airlines
Mon, Mar 9 - Tue, Mar 17
Multiple Airlines Logo
8:12 pm - 8:55 am
STL
-
SNA
38h 43m
2 stops
Multiple Airlines Logo
4:37 pm - 11:19 am
SNA
-
STL
16h 42m
1 stop
$205Multiple Airlines
Mon, Mar 9 - Tue, Mar 17
Multiple Airlines Logo
8:12 pm - 12:22 pm
STL
-
SNA
42h 10m
2 stops
Multiple Airlines Logo
8:20 pm - 11:19 am
SNA
-
STL
12h 59m
1 stop
$228Multiple Airlines
Mon, Mar 16 - Thu, Mar 26
Frontier Logo
10:47 pm - 8:50 am
STL
-
SNA
12h 03m
1 stop
Frontier Logo
1:12 pm - 11:19 am
SNA
-
STL
20h 07m
1 stop
$249Frontier
Thu, Mar 19 - Mon, Mar 30
Alaska Airlines Logo
7:00 am - 2:13 pm
STL
-
SNA
9h 13m
1 stop
Alaska Airlines Logo
3:01 pm - 1:51 pm
SNA
-
STL
20h 50m
1 stop
$257Alaska Airlines
Wed, Feb 25 - Wed, Mar 4
United Airlines Logo
6:00 am - 11:13 am
STL
-
SNA
7h 13m
1 stop
United Airlines Logo
11:10 am - 9:08 pm
SNA
-
STL
7h 58m
2 stops
$262United Airlines
Wed, Apr 15 - Sat, Apr 18
Multiple Airlines Logo
5:18 pm - 8:13 am
STL
-
SNA
16h 55m
2 stops
Multiple Airlines Logo
1:20 pm - 9:26 pm
SNA
-
STL
6h 06m
1 stop
$264Multiple Airlines
Wed, Mar 4 - Thu, Mar 5
Frontier Logo
10:47 pm - 8:50 am
STL
-
SNA
12h 03m
1 stop
Frontier Logo
2:23 pm - 9:48 am
SNA
-
STL
41h 25m
2 stops
$265Frontier
Thu, Mar 19 - Mon, Mar 30
Multiple Airlines Logo
10:47 pm - 8:50 am
STL
-
SNA
12h 03m
1 stop
Multiple Airlines Logo
4:37 pm - 9:48 am
SNA
-
STL
15h 11m
2 stops
$272Multiple Airlines
Thu, Mar 19 - Tue, Mar 31
Delta Logo
3:05 pm - 8:56 pm
STL
-
SNA
7h 51m
1 stop
Delta Logo
8:00 am - 5:05 pm
SNA
-
STL
7h 05m
1 stop
$277Delta
Tue, Mar 10 - Wed, Mar 18

Alaska Airlines flights from St. Louis to Santa Ana, California

Our best Alaska Airlines deals on St. Louis to Santa Ana, California flight tickets
Alaska Airlines
Feb 25
STL7:00 amLambert-St Louis
9h 13m
1 stop
SNA2:13 pmSanta Ana J. Wayne/Orange Cnty
Mar 4
SNA3:01 pmSanta Ana J. Wayne/Orange Cnty
20h 50m
1 stop
STL1:51 pmLambert-St Louis
$257
Alaska Airlines
Mar 4
STL7:00 amLambert-St Louis
11h 26m
1 stop
SNA4:26 pmSanta Ana J. Wayne/Orange Cnty
Mar 7
SNA3:01 pmSanta Ana J. Wayne/Orange Cnty
20h 22m
1 stop
STL1:23 pmLambert-St Louis
$306
Alaska Airlines
Feb 27
STL7:00 amLambert-St Louis
11h 26m
1 stop
SNA4:26 pmSanta Ana J. Wayne/Orange Cnty
Mar 3
SNA3:01 pmSanta Ana J. Wayne/Orange Cnty
20h 50m
1 stop
STL1:51 pmLambert-St Louis
$316

Delta flights from St. Louis to Santa Ana, California

Our best Delta deals on St. Louis to Santa Ana, California flight tickets
Delta
Mar 10
STL3:05 pmLambert-St Louis
7h 51m
1 stop
SNA8:56 pmSanta Ana J. Wayne/Orange Cnty
Mar 18
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
7h 05m
1 stop
STL5:05 pmLambert-St Louis
$277
Delta
Mar 10
STL3:05 pmLambert-St Louis
7h 51m
1 stop
SNA8:56 pmSanta Ana J. Wayne/Orange Cnty
Mar 17
SNA11:05 amSanta Ana J. Wayne/Orange Cnty
20h 41m
2 stops
STL9:46 amLambert-St Louis
$295
Delta
Mar 10
STL3:05 pmLambert-St Louis
7h 51m
1 stop
SNA8:56 pmSanta Ana J. Wayne/Orange Cnty
Mar 16
SNA7:30 amSanta Ana J. Wayne/Orange Cnty
14h 51m
2 stops
STL12:21 amLambert-St Louis
$313

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from St. Louis to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 3/9

12:14 pm-8:57 pm

1 stop10h 43m

Santa Ana J. Wayne/Orange Cnty

Tue 3/17

1:20 pm-11:19 am

1 stop19h 59m

$197

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 3/9

8:12 pm-8:55 am

2 stops38h 43m

Santa Ana J. Wayne/Orange Cnty

Tue 3/17

4:37 pm-11:19 am

1 stop16h 42m

$205

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 3/16

8:12 pm-12:22 pm

2 stops42h 10m

Santa Ana J. Wayne/Orange Cnty

Thu 3/26

8:20 pm-11:19 am

1 stop12h 59m

$228

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 3/19

10:47 pm-8:50 am

1 stop12h 03m

Santa Ana J. Wayne/Orange Cnty

Mon 3/30

1:12 pm-11:19 am

1 stop20h 07m

$249

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 2/25

7:00 am-2:13 pm

1 stop9h 13m

Santa Ana J. Wayne/Orange Cnty

Wed 3/4

3:01 pm-1:51 pm

1 stop20h 50m

$257

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 4/15

6:00 am-11:13 am

1 stop7h 13m

Santa Ana J. Wayne/Orange Cnty

Sat 4/18

11:10 am-9:08 pm

2 stops7h 58m

$262

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 3/4

5:18 pm-8:13 am

2 stops16h 55m

Santa Ana J. Wayne/Orange Cnty

Thu 3/5

1:20 pm-9:26 pm

1 stop6h 06m

$264

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 3/19

10:47 pm-8:50 am

1 stop12h 03m

Santa Ana J. Wayne/Orange Cnty

Mon 3/30

2:23 pm-9:48 am

2 stops41h 25m

$265

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 3/19

10:47 pm-8:50 am

1 stop12h 03m

Santa Ana J. Wayne/Orange Cnty

Tue 3/31

4:37 pm-9:48 am

2 stops15h 11m

$272

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Tue 3/10

3:05 pm-8:56 pm

1 stop7h 51m

Santa Ana J. Wayne/Orange Cnty

Wed 3/18

8:00 am-5:05 pm

1 stop7h 05m

$277

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from St. Louis to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, November is the cheapest month to fly from St. Louis to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $345. If you aren’t able to travel during the month of November, then book flights to Santa Ana, California from St. Louis during April instead. Flights to Santa Ana, California in April, while not as cheap as those in November, still average around $366.

How far in advance should I book a flight to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $438 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from St. Louis for as low as $328 on momondo.

How have St. Louis to Santa Ana, California flight prices changed over time?

As of January 2026, prices for St. Louis to Santa Ana, California flights are approximately 58% more expensive when compared to flights at the same time last year.

When to book flights from St. Louis to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap St. Louis to Santa Ana, California (STL to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santa Ana, California

Fastest flight time

5h 46m

Direct flights

None
The fastest flight from St. Louis to Santa Ana, California takes 5h 46m
There are no direct flights from St. Louis to Santa Ana, California. There are no popular flight routes from St. Louis to Santa Ana, California.
Search flight deals

  • How far is Lambert-St Louis to Santa Ana J. Wayne/Orange Cnty by plane?

    Lambert-St Louis and Santa Ana J. Wayne/Orange Cnty are 1572.0 mi apart from one another. A reasonable flight in good conditions will take 5h 46m.

  • When did momondo last update prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents you'll need for your trip to Santa Ana J. Wayne/Orange Cnty Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santa Ana J. Wayne/Orange Cnty Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from St. Louis to Santa Ana, California?

Best airlines flying from St. Louis to Santa Ana, California

Compare and see reviews for airlines that fly from St. Louis to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $126Free CancellationRating
5.7
3,056 reviews
Search Frontier flights
American AirlinesPriceFrom $294Free CancellationRating
7.2
11,206 reviews
Search American Airlines flights
United AirlinesPriceFrom $322Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights
SouthwestPriceFrom $332Free CancellationRating
8.0
4,267 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from St. Louis to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from St. Louis to Santa Ana with flexible booking policies on momondo?

All flight searches from St. Louis to Santa Ana on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from St. Louis to Santa Ana?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Ana from St. Louis.

I’m not ready to book a flight from St. Louis to Santa Ana right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santa Ana from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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