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Cheap flights from Roanoke to San Diego from $234

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to San Diego departing on 11/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Roanoke to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
3:55 pm - 8:41 pmROA-SAN
7h 46m1 stop
Delta Logo
2:15 pm - 12:10 amSAN-ROA
6h 55m1 stop
$309Delta
Find Deal
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
5:40 pm - 10:30 pmROA-SAN
7h 50m1 stop
United Airlines Logo
8:00 pm - 10:06 amSAN-ROA
11h 06m2 stops
$314United Airlines
Find Deal
Thu, Dec 11 - Mon, Dec 15
American Airlines Logo
8:00 am - 3:03 pmROA-SAN
10h 03m2 stops
American Airlines Logo
10:09 am - 10:53 pmSAN-ROA
9h 44m2 stops
$319American Airlines
Find Deal
Thu, Jan 8 - Wed, Jan 14
United Airlines Logo
2:55 pm - 8:52 pmROA-SAN
8h 57m1 stop
United Airlines Logo
10:30 pm - 10:16 amSAN-ROA
8h 46m1 stop
$328United Airlines
Find Deal
Thu, Dec 25 - Mon, Dec 29
United Airlines Logo
2:55 pm - 8:52 pmROA-SAN
8h 57m1 stop
United Airlines Logo
12:56 pm - 11:30 pmSAN-ROA
7h 34m1 stop
$329United Airlines
Find Deal
Thu, Dec 25 - Mon, Dec 29
United Airlines Logo
2:55 pm - 8:52 pmROA-SAN
8h 57m1 stop
United Airlines Logo
10:30 pm - 10:16 amSAN-ROA
8h 46m1 stop
$331United Airlines
Find Deal
Thu, Dec 25 - Mon, Dec 29
American Airlines Logo
6:00 am - 11:21 amROA-SAN
8h 21m1 stop
American Airlines Logo
1:39 pm - 11:44 pmSAN-ROA
7h 05m1 stop
$349American Airlines
Find Deal
Sat, Feb 28 - Sat, Mar 7
American Airlines Logo
10:09 am - 6:25 pmROA-SAN
11h 16m2 stops
American Airlines Logo
10:01 pm - 8:42 amSAN-ROA
7h 41m1 stop
$354American Airlines
Find Deal
Tue, Dec 16 - Wed, Dec 31
Delta Logo
3:55 pm - 8:41 pmROA-SAN
7h 46m1 stop
Delta Logo
11:00 am - 10:41 amSAN-ROA
20h 41m2 stops
$358Delta
Find Deal
Sat, Feb 21 - Wed, Feb 25
American Airlines Logo
11:04 am - 7:19 pmROA-SAN
11h 15m2 stops
American Airlines Logo
6:35 am - 5:36 pmSAN-ROA
8h 01m1 stop
$452American Airlines
Find Deal
Sat, Feb 28 - Sat, Mar 7

Delta flights from Roanoke to San Diego

Our best Delta deals on Roanoke to San Diego flight tickets
Delta
Feb 21
ROA3:55 pmRoanoke
7h 46m
1 stop
SAN8:41 pmSan Diego
Feb 25
SAN2:15 pmSan Diego
6h 55m
1 stop
ROA12:10 amRoanoke
$309
Find similar
Delta
Feb 21
ROA3:55 pmRoanoke
7h 46m
1 stop
SAN8:41 pmSan Diego
Feb 25
SAN11:00 amSan Diego
20h 41m
2 stops
ROA10:41 amRoanoke
$358
Find similar
Delta
Nov 17
ROA3:50 pmRoanoke
7h 23m
1 stop
SAN8:13 pmSan Diego
Nov 23
SAN12:16 pmSan Diego
8h 59m
1 stop
ROA12:15 amRoanoke
$479
Find similar

United Airlines flights from Roanoke to San Diego

Our best United Airlines deals on Roanoke to San Diego flight tickets
United Airlines
Dec 11
ROA5:40 pmRoanoke
7h 50m
1 stop
SAN10:30 pmSan Diego
Dec 15
SAN8:00 pmSan Diego
11h 06m
2 stops
ROA10:06 amRoanoke
$314
Find similar
United Airlines
Dec 25
ROA2:55 pmRoanoke
8h 57m
1 stop
SAN8:52 pmSan Diego
Dec 29
SAN10:30 pmSan Diego
8h 46m
1 stop
ROA10:16 amRoanoke
$328
Find similar
United Airlines
Dec 25
ROA2:55 pmRoanoke
8h 57m
1 stop
SAN8:52 pmSan Diego
Dec 29
SAN12:56 pmSan Diego
7h 34m
1 stop
ROA11:30 pmRoanoke
$329
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Roanoke to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 2/21

3:55 pm-8:41 pm

1 stop7h 46m

San Diego

Wed 2/25

2:15 pm-12:10 am

1 stop6h 55m

$309

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Thu 12/11

5:40 pm-10:30 pm

1 stop7h 50m

San Diego

Mon 12/15

8:00 pm-10:06 am

2 stops11h 06m

$314

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Thu 1/8

8:00 am-3:03 pm

2 stops10h 03m

San Diego

Wed 1/14

10:09 am-10:53 pm

2 stops9h 44m

$319

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Thu 12/25

2:55 pm-8:52 pm

1 stop8h 57m

San Diego

Mon 12/29

10:30 pm-10:16 am

1 stop8h 46m

$328

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Thu 12/25

2:55 pm-8:52 pm

1 stop8h 57m

San Diego

Mon 12/29

12:56 pm-11:30 pm

1 stop7h 34m

$329

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Thu 12/25

2:55 pm-8:52 pm

1 stop8h 57m

San Diego

Mon 12/29

10:30 pm-10:16 am

1 stop8h 46m

$331

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 2/28

6:00 am-11:21 am

1 stop8h 21m

San Diego

Sat 3/7

1:39 pm-11:44 pm

1 stop7h 05m

$349

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Tue 12/16

10:09 am-6:25 pm

2 stops11h 16m

San Diego

Wed 12/31

10:01 pm-8:42 am

1 stop7h 41m

$354

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 2/21

3:55 pm-8:41 pm

1 stop7h 46m

San Diego

Wed 2/25

11:00 am-10:41 am

2 stops20h 41m

$358

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 2/28

11:04 am-7:19 pm

2 stops11h 15m

San Diego

Sat 3/7

6:35 am-5:36 pm

1 stop8h 01m

$452

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Roanoke to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of September, then departing from Roanoke during the month May is also very affordable. Most momondo users find prices during this month for around $398.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Roanoke to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $430. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $753. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $312. Flights in the afternoon are often more expensive with an average ticket price of $482.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Roanoke when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $464 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Roanoke for as low as $333 on momondo.

When to book flights from Roanoke to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to San Diego (ROA to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to San Diego

Direct flights

None
There are no direct flights from Roanoke to San Diego. There are no popular flight routes from Roanoke to San Diego.
Search flight deals

  • How far is Roanoke to San Diego by plane?

    Roanoke and San Diego are 2114.7 mi apart from one another. In terms of flight time, this usually takes a little over 7h 42m.

  • When did momondo last update prices for flights from Roanoke Airport to San Diego Airport?

    Prices for flights from Roanoke Airport to San Diego Airport refresh daily.

  • How many operators does momondo search for flights from Roanoke Airport to San Diego Airport?

  • How old do you have to be to fly from Roanoke Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Roanoke to San Diego?

Best airlines flying from Roanoke to San Diego

Compare and see reviews for airlines that fly from Roanoke to San Diego with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $278Free CancellationRating
7.4
9,007 reviews
Search United Airlines flights
DeltaPriceFrom $296Free CancellationRating
7.9
8,001 reviews
Search Delta flights
American AirlinesPriceFrom $308Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
National City
Imperial Beach
La Mesa
Poway
Borrego Springs
San Ysidro
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to San Diego?

Finding the right flight to San Diego from Roanoke is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Roanoke to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Roanoke to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Roanoke to San Diego?

Once you have performed a search for Roanoke to San Diego flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Roanoke to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Roanoke to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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