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Cheap flights from Roanoke to San Diego from $255

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to San Diego departing on 10/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Roanoke to San Diego

Cheap round-trip flights

Delta Logo
3:42 pm - 9:20 pmROA-SAN
8h 38m1 stop
Delta Logo
2:05 pm - 12:09 amSAN-ROA
7h 04m1 stop
$309Delta
Find Deal
Sat, Oct 18 - Sat, Oct 25
American Airlines Logo
2:23 pm - 6:46 pmROA-SAN
7h 23m1 stop
American Airlines Logo
10:23 am - 10:25 pmSAN-ROA
9h 02m2 stops
$314American Airlines
Find Deal
Sat, Oct 18 - Sat, Oct 25
American Airlines Logo
11:07 am - 6:04 pmROA-SAN
9h 57m2 stops
American Airlines Logo
10:23 am - 10:25 pmSAN-ROA
9h 02m2 stops
$319American Airlines
Find Deal
Sat, Oct 18 - Sat, Oct 25
American Airlines Logo
6:00 am - 11:14 amROA-SAN
8h 14m1 stop
American Airlines Logo
12:54 pm - 11:59 pmSAN-ROA
8h 05m1 stop
$339American Airlines
Find Deal
Sun, Oct 12 - Sat, Oct 18
American Airlines Logo
7:03 am - 11:12 amROA-SAN
7h 09m1 stop
American Airlines Logo
8:01 pm - 7:32 amSAN-ROA
8h 31m2 stops
$344American Airlines
Find Deal
Sat, Feb 28 - Sat, Mar 7
American Airlines Logo
5:22 am - 9:30 amROA-SAN
7h 08m1 stop
American Airlines Logo
6:55 am - 8:12 pmSAN-ROA
10h 17m1 stop
$349American Airlines
Find Deal
Sat, Feb 28 - Sat, Mar 7
United Airlines Logo
10:30 am - 3:01 pmROA-SAN
7h 31m1 stop
United Airlines Logo
6:53 am - 9:41 pmSAN-ROA
11h 48m2 stops
$353United Airlines
Find Deal
Sat, Oct 18 - Sat, Oct 25
Delta Logo
3:25 pm - 8:56 pmROA-SAN
8h 31m1 stop
Delta Logo
6:15 am - 11:49 pmSAN-ROA
14h 34m2 stops
$388Delta
Find Deal
Sat, Feb 21 - Wed, Feb 25
United Airlines Logo
10:30 am - 3:01 pmROA-SAN
7h 31m1 stop
United Airlines Logo
12:35 pm - 11:24 pmSAN-ROA
7h 49m1 stop
$409United Airlines
Find Deal
Sun, Oct 12 - Sat, Oct 18
United Airlines Logo
5:40 pm - 10:14 pmROA-SAN
7h 34m1 stop
United Airlines Logo
6:15 am - 11:24 pmSAN-ROA
14h 09m2 stops
$414United Airlines
Find Deal
Sun, Oct 12 - Sat, Oct 18

United Airlines flights from Roanoke to San Diego

Our best United Airlines deals on Roanoke to San Diego flight tickets
United Airlines
Oct 18
ROA10:30 amRoanoke
7h 31m
1 stop
SAN3:01 pmSan Diego
Oct 25
SAN6:53 amSan Diego
11h 48m
2 stops
ROA9:41 pmRoanoke
$353
Find similar
United Airlines
Oct 12
ROA10:30 amRoanoke
7h 31m
1 stop
SAN3:01 pmSan Diego
Oct 18
SAN12:35 pmSan Diego
7h 49m
1 stop
ROA11:24 pmRoanoke
$409
Find similar
United Airlines
Oct 12
ROA5:40 pmRoanoke
7h 34m
1 stop
SAN10:14 pmSan Diego
Oct 18
SAN6:15 amSan Diego
14h 09m
2 stops
ROA11:24 pmRoanoke
$414
Find similar

American Airlines flights from Roanoke to San Diego

Our best American Airlines deals on Roanoke to San Diego flight tickets
American Airlines
Oct 18
ROA2:23 pmRoanoke
7h 23m
1 stop
SAN6:46 pmSan Diego
Oct 25
SAN10:23 amSan Diego
9h 02m
2 stops
ROA10:25 pmRoanoke
$314
Find similar
American Airlines
Oct 18
ROA11:07 amRoanoke
9h 57m
2 stops
SAN6:04 pmSan Diego
Oct 25
SAN10:23 amSan Diego
9h 02m
2 stops
ROA10:25 pmRoanoke
$319
Find similar
American Airlines
Oct 12
ROA6:00 amRoanoke
8h 14m
1 stop
SAN11:14 amSan Diego
Oct 18
SAN12:54 pmSan Diego
8h 05m
1 stop
ROA11:59 pmRoanoke
$339
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 10, 2025.
Use the filters below to find and compare flights from Roanoke to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 10/18

3:42 pm-9:20 pm

1 stop8h 38m

San Diego

Sat 10/25

2:05 pm-12:09 am

1 stop7h 04m

$309

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 10/18

2:23 pm-6:46 pm

1 stop7h 23m

San Diego

Sat 10/25

10:23 am-10:25 pm

2 stops9h 02m

$314

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 10/18

11:07 am-6:04 pm

2 stops9h 57m

San Diego

Sat 10/25

10:23 am-10:25 pm

2 stops9h 02m

$319

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sun 10/12

6:00 am-11:14 am

1 stop8h 14m

San Diego

Sat 10/18

12:54 pm-11:59 pm

1 stop8h 05m

$339

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 2/28

7:03 am-11:12 am

1 stop7h 09m

San Diego

Sat 3/7

8:01 pm-7:32 am

2 stops8h 31m

$344

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 2/28

5:22 am-9:30 am

1 stop7h 08m

San Diego

Sat 3/7

6:55 am-8:12 pm

1 stop10h 17m

$349

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 10/18

10:30 am-3:01 pm

1 stop7h 31m

San Diego

Sat 10/25

6:53 am-9:41 pm

2 stops11h 48m

$353

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sat 2/21

3:25 pm-8:56 pm

1 stop8h 31m

San Diego

Wed 2/25

6:15 am-11:49 pm

2 stops14h 34m

$388

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sun 10/12

10:30 am-3:01 pm

1 stop7h 31m

San Diego

Sat 10/18

12:35 pm-11:24 pm

1 stop7h 49m

$409

RoanokeSan Diego

ROA - SAN

ROASAN

Roanoke

Sun 10/12

5:40 pm-10:14 pm

1 stop7h 34m

San Diego

Sat 10/18

6:15 am-11:24 pm

2 stops14h 09m

$414

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Roanoke to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of May, then departing from Roanoke during the month September is also very affordable. Most momondo users find prices during this month for around $422.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Roanoke to San Diego is on a Friday. Travelers who choose to depart for San Diego on a Friday will often find tickets for as low as $430. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $753. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $312. Flights in the afternoon are often more expensive with an average ticket price of $482.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Roanoke when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $475 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Roanoke for as low as $342 on momondo.

How have Roanoke to San Diego flight prices changed over time?

When to book flights from Roanoke to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to San Diego (ROA to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to San Diego

Direct flights

None
There are no direct flights from Roanoke to San Diego. There are no popular flight routes from Roanoke to San Diego.
Search flight deals

  • How far is Roanoke to San Diego by plane?

    Roanoke and San Diego are 2114.7 mi apart from one another. In terms of flight time, this usually takes a little over 7h 08m.

  • When did momondo last update prices for flights from Roanoke Airport to San Diego Airport?

    Prices for flights from Roanoke Airport to San Diego Airport refresh daily.

  • How many operators does momondo search for flights from Roanoke Airport to San Diego Airport?

  • How old do you have to be to fly from Roanoke Airport to San Diego Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Roanoke to San Diego?

Best airlines flying from Roanoke to San Diego

Compare and see reviews for airlines that fly from Roanoke to San Diego with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $278Free CancellationRating
7.4
8,937 reviews
Search United Airlines flights
DeltaPriceFrom $296Free CancellationRating
7.9
7,963 reviews
Search Delta flights
American AirlinesPriceFrom $308Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
La Mesa
National City
Imperial Beach
Poway
San Ysidro
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to San Diego?

Finding the right flight to San Diego from Roanoke is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Diego quick and easy, saving you time and money.

Can I find flights from Roanoke to San Diego with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Roanoke to San Diego flights to just show those with flexible booking policies.

How can momondo help me find flights from Roanoke to San Diego?

Once you have performed a search for Roanoke to San Diego flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Roanoke to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Roanoke to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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