Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Portland to Florence from $427

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Florence departing on 8/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Portland to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:00 am - 9:47 pm
PDX
-
FLO
12h 47m
2 stops
American Airlines Logo
4:16 pm - 11:57 pm
FLO
-
PDX
10h 41m
2 stops
$609American Airlines
Fri, May 1 - Mon, May 4
American Airlines Logo
7:23 am - 10:42 pm
PDX
-
FLO
12h 19m
2 stops
American Airlines Logo
4:16 pm - 9:03 pm
FLO
-
PDX
7h 47m
1 stop
$624American Airlines
Tue, Apr 14 - Sat, Apr 18
American Airlines Logo
11:40 pm - 3:50 pm
PDX
-
FLO
13h 10m
2 stops
American Airlines Logo
4:16 pm - 11:03 pm
FLO
-
PDX
9h 47m
2 stops
$629American Airlines
Tue, Apr 14 - Sat, Apr 18
American Airlines Logo
6:00 am - 9:47 pm
PDX
-
FLO
12h 47m
2 stops
American Airlines Logo
4:16 pm - 9:03 pm
FLO
-
PDX
7h 47m
1 stop
$646American Airlines
Fri, May 1 - Mon, May 4
American Airlines Logo
12:59 am - 3:50 pm
PDX
-
FLO
11h 51m
2 stops
American Airlines Logo
4:16 pm - 11:57 pm
FLO
-
PDX
10h 41m
2 stops
$671American Airlines
Sun, Apr 26 - Mon, May 4
American Airlines Logo
6:00 am - 9:47 pm
PDX
-
FLO
12h 47m
2 stops
American Airlines Logo
4:16 pm - 9:03 pm
FLO
-
PDX
7h 47m
1 stop
$708American Airlines
Mon, Apr 27 - Mon, May 4
American Airlines Logo
10:23 pm - 9:47 pm
PDX
-
FLO
20h 24m
1 stop
American Airlines Logo
5:20 am - 9:03 pm
FLO
-
PDX
18h 43m
1 stop
$898American Airlines
Fri, May 1 - Mon, May 4
American Airlines Logo
11:23 pm - 3:50 pm
PDX
-
FLO
13h 27m
1 stop
American Airlines Logo
5:20 am - 9:03 pm
FLO
-
PDX
18h 43m
1 stop
$941American Airlines
Tue, Apr 14 - Sat, Apr 18
American Airlines Logo
10:23 pm - 10:42 pm
PDX
-
FLO
21h 19m
1 stop
American Airlines Logo
5:20 am - 9:03 pm
FLO
-
PDX
18h 43m
1 stop
$953American Airlines
Mon, Apr 27 - Mon, May 4

American Airlines flights from Portland to Florence, South Carolina

Our best American Airlines deals on Portland to Florence, South Carolina flight tickets
American Airlines
May 1
PDX6:00 amPortland
12h 47m
2 stops
FLO9:47 pmFlorence
May 4
FLO4:16 pmFlorence
10h 41m
2 stops
PDX11:57 pmPortland
$609
American Airlines
Apr 14
PDX7:23 amPortland
12h 19m
2 stops
FLO10:42 pmFlorence
Apr 18
FLO4:16 pmFlorence
7h 47m
1 stop
PDX9:03 pmPortland
$624
American Airlines
Apr 14
PDX11:40 pmPortland
13h 10m
2 stops
FLO3:50 pmFlorence
Apr 18
FLO4:16 pmFlorence
9h 47m
2 stops
PDX11:03 pmPortland
$629

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from Portland to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Fri 5/1

6:00 am-9:47 pm

2 stops12h 47m

Florence

Mon 5/4

4:16 pm-11:57 pm

2 stops10h 41m

$609
Quickest round-trip

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Tue 4/14

7:23 am-10:42 pm

2 stops12h 19m

Florence

Sat 4/18

4:16 pm-9:03 pm

1 stop7h 47m

$624

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Tue 4/14

11:40 pm-3:50 pm

2 stops13h 10m

Florence

Sat 4/18

4:16 pm-11:03 pm

2 stops9h 47m

$629

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Fri 5/1

6:00 am-9:47 pm

2 stops12h 47m

Florence

Mon 5/4

4:16 pm-9:03 pm

1 stop7h 47m

$646

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Sun 4/26

12:59 am-3:50 pm

2 stops11h 51m

Florence

Mon 5/4

4:16 pm-11:57 pm

2 stops10h 41m

$671

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Mon 4/27

6:00 am-9:47 pm

2 stops12h 47m

Florence

Mon 5/4

4:16 pm-9:03 pm

1 stop7h 47m

$708

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Fri 5/1

10:23 pm-9:47 pm

1 stop20h 24m

Florence

Mon 5/4

5:20 am-9:03 pm

1 stop18h 43m

$898

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Tue 4/14

11:23 pm-3:50 pm

1 stop13h 27m

Florence

Sat 4/18

5:20 am-9:03 pm

1 stop18h 43m

$941

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Mon 4/27

10:23 pm-10:42 pm

1 stop21h 19m

Florence

Mon 5/4

5:20 am-9:03 pm

1 stop18h 43m

$953
Cheapest one-way

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Thu 8/20

7:00 am-12:02 am

2 stops14h 02m

$427

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

See travel insights to Florence from

How to get the cheapest flight ticket from Portland to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Portland to Florence?

American Airlines is the most popular carrier operating from Portland to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Florence, South Carolina from Portland according to our data. American Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 6 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Portland to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Florence, South Carolina (PDX to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Florence, South Carolina

Fastest flight time

12h 19m

Direct flights

None
The fastest flight from Portland to Florence, South Carolina takes 12h 19m
There are no direct flights from Portland to Florence, South Carolina. There are no popular flight routes from Portland to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Portland to Florence, South Carolina

  • How far is Portland to Florence by plane?

    There are 2372.9 mi between Portland and Florence. In terms of flight time, this usually takes a little over 12h 19m.

  • When did momondo last update prices for flights from Portland Airport to Florence Airport?

    Prices for flights from Portland Airport to Florence Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Portland Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Darlington
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Florence?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Portland to Florence. momondo saves you time and could save you money on your trip.

Can I find flights from Portland to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Portland with this policy.

How can momondo help me find flights from Portland to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Portland.

I’m not ready to book a flight from Portland to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Portland to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Florence, South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 5/2
Sat 5/9
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States