Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Portland to Florence from $644

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Florence departing on 8/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Portland to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:07 am - 11:37 pm
PDX
-
FLO
14h 30m
2 stops
American Airlines Logo
6:22 am - 11:48 am
FLO
-
PDX
8h 26m
1 stop
$644American Airlines
Tue, Aug 4 - Tue, Sep 1
American Airlines Logo
6:39 am - 11:37 pm
PDX
-
FLO
13h 58m
2 stops
American Airlines Logo
6:22 am - 4:51 pm
FLO
-
PDX
13h 29m
2 stops
$713American Airlines
Tue, Aug 4 - Tue, Sep 1
American Airlines Logo
7:00 am - 11:37 pm
PDX
-
FLO
13h 37m
2 stops
American Airlines Logo
3:22 pm - 7:48 pm
FLO
-
PDX
7h 26m
1 stop
$739American Airlines
Sun, Aug 2 - Sat, Aug 8
American Airlines Logo
7:00 am - 11:37 pm
PDX
-
FLO
13h 37m
2 stops
American Airlines Logo
6:22 am - 4:51 pm
FLO
-
PDX
13h 29m
2 stops
$877American Airlines
Sun, Aug 2 - Sat, Aug 8
American Airlines Logo
9:47 pm - 2:10 pm
PDX
-
FLO
13h 23m
1 stop
American Airlines Logo
6:22 am - 7:48 pm
FLO
-
PDX
16h 26m
1 stop
$919American Airlines
Sun, Aug 2 - Sat, Aug 8
American Airlines Logo
9:47 pm - 2:56 pm
PDX
-
FLO
14h 09m
1 stop
American Airlines Logo
6:22 am - 11:48 am
FLO
-
PDX
8h 26m
1 stop
$965American Airlines
Tue, Aug 4 - Tue, Sep 1

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Portland to Florence, South Carolina

Our best American Airlines deals on Portland to Florence, South Carolina flight tickets
American Airlines
Aug 4
PDX6:07 amPortland
14h 30m
2 stops
FLO11:37 pmFlorence
Sep 1
FLO6:22 amFlorence
8h 26m
1 stop
PDX11:48 amPortland
$644
American Airlines
Aug 4
PDX6:39 amPortland
13h 58m
2 stops
FLO11:37 pmFlorence
Sep 1
FLO6:22 amFlorence
13h 29m
2 stops
PDX4:51 pmPortland
$713
American Airlines
Aug 2
PDX7:00 amPortland
13h 37m
2 stops
FLO11:37 pmFlorence
Aug 8
FLO3:22 pmFlorence
7h 26m
1 stop
PDX7:48 pmPortland
$739

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 6, 2026.
Use the filters below to find and compare flights from Portland to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Tue 8/4

6:07 am-11:37 pm

2 stops14h 30m

Florence

Tue 9/1

6:22 am-11:48 am

1 stop8h 26m

$644

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Tue 8/4

6:39 am-11:37 pm

2 stops13h 58m

Florence

Tue 9/1

6:22 am-4:51 pm

2 stops13h 29m

$713
Quickest round-trip

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Sun 8/2

7:00 am-11:37 pm

2 stops13h 37m

Florence

Sat 8/8

3:22 pm-7:48 pm

1 stop7h 26m

$739

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Sun 8/2

7:00 am-11:37 pm

2 stops13h 37m

Florence

Sat 8/8

6:22 am-4:51 pm

2 stops13h 29m

$877

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Sun 8/2

9:47 pm-2:10 pm

1 stop13h 23m

Florence

Sat 8/8

6:22 am-7:48 pm

1 stop16h 26m

$919

PortlandFlorence

PDX - FLO

PDXFLO

Portland

Tue 8/4

9:47 pm-2:56 pm

1 stop14h 09m

Florence

Tue 9/1

6:22 am-11:48 am

1 stop8h 26m

$965

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Portland to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Florence, South Carolina from Portland according to our data. American Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 6 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Portland to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Florence, South Carolina (PDX to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Florence, South Carolina

Fastest flight time

14h 30m

Direct flights

None
The fastest flight from Portland to Florence, South Carolina takes 14h 30m
There are no direct flights from Portland to Florence, South Carolina. There are no popular flight routes from Portland to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Portland to Florence, South Carolina

  • How far is Portland to Florence by plane?

    There are 2372.9 mi between Portland and Florence. In terms of flight time, this usually takes a little over 14h 30m.

  • When did momondo last update prices for flights from Portland Airport to Florence Airport?

    Prices for flights from Portland Airport to Florence Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Portland Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The required travel and health documents for your Florence Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florence Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Florence?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Portland to Florence. momondo saves you time and could save you money on your trip.

Can I find flights from Portland to Florence with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Florence from Portland with this policy.

How can momondo help me find flights from Portland to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Portland.

I’m not ready to book a flight from Portland to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Portland to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Florence, South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 8/5
Wed 8/12
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States