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Cheap flights from Panama to Los Angeles from $381

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Los Angeles departing on 1/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama to Los Angeles

Recent round-trip flight deals from Panama to Los Angeles

Enter your travel dates to find the best prices.
United Airlines Logo
3:30 pm - 11:13 am
PTY
-
SNA
21h 43m1 stop
United Airlines Logo
6:28 pm - 4:12 pm
SNA
-
PTY
19h 44m2 stops
$653United Airlines
Thu, Apr 23 - Mon, Apr 27
United Airlines Logo
4:41 pm - 12:18 pm
PTY
-
SNA
22h 37m2 stops
United Airlines Logo
6:28 pm - 6:37 pm
SNA
-
PTY
22h 09m2 stops
$674United Airlines
Sat, Feb 14 - Mon, Apr 27
United Airlines Logo
11:35 am - 9:42 pm
PTY
-
SNA
13h 07m1 stop
United Airlines Logo
3:45 pm - 2:45 pm
SNA
-
PTY
20h 00m2 stops
$695United Airlines
Sun, Feb 8 - Sun, Feb 15
United Airlines Logo
8:55 am - 8:42 pm
PTY
-
SNA
14h 47m2 stops
United Airlines Logo
6:35 pm - 5:07 pm
SNA
-
PTY
19h 32m3 stops
$717United Airlines
Sat, Feb 7 - Sat, Feb 14
United Airlines Logo
8:55 am - 9:42 pm
PTY
-
SNA
15h 47m1 stop
United Airlines Logo
8:00 am - 7:38 pm
SNA
-
PTY
8h 38m1 stop
$726United Airlines
Tue, Jan 20 - Sat, Jan 24
United Airlines Logo
4:41 pm - 1:11 pm
PTY
-
SNA
23h 30m2 stops
United Airlines Logo
6:25 pm - 5:07 pm
SNA
-
PTY
19h 42m2 stops
$730United Airlines
Tue, Jan 20 - Sat, Jan 24
United Airlines Logo
8:55 am - 9:42 pm
PTY
-
SNA
15h 47m1 stop
United Airlines Logo
8:00 am - 7:38 pm
SNA
-
PTY
8h 38m1 stop
$747United Airlines
Tue, Jan 20 - Sat, Jan 24
United Airlines Logo
4:41 pm - 12:15 pm
PTY
-
SNA
22h 34m2 stops
United Airlines Logo
3:45 pm - 2:45 pm
SNA
-
PTY
20h 00m2 stops
$1,431United Airlines
Sun, Feb 8 - Sun, Feb 15

United Airlines flights from Panama to Santa Ana, California

Our best United Airlines deals on Panama to Santa Ana, California flight tickets
United Airlines
Apr 23
PTY3:30 pmPanama City Tocumen Intl
21h 43m
1 stop
SNA11:13 amSanta Ana J. Wayne/Orange Cnty
Apr 27
SNA6:28 pmSanta Ana J. Wayne/Orange Cnty
19h 44m
2 stops
PTY4:12 pmPanama City Tocumen Intl
$653
Find similar
United Airlines
Feb 14
PTY4:41 pmPanama City Tocumen Intl
22h 37m
2 stops
SNA12:18 pmSanta Ana J. Wayne/Orange Cnty
Apr 27
SNA6:28 pmSanta Ana J. Wayne/Orange Cnty
22h 09m
2 stops
PTY6:37 pmPanama City Tocumen Intl
$674
Find similar
United Airlines
Feb 8
PTY11:35 amPanama City Tocumen Intl
13h 07m
1 stop
SNA9:42 pmSanta Ana J. Wayne/Orange Cnty
Feb 15
SNA3:45 pmSanta Ana J. Wayne/Orange Cnty
20h 00m
2 stops
PTY2:45 pmPanama City Tocumen Intl
$695
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 25, 2025.
Use the filters below to find and compare flights from Panama to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Thu 4/23

3:30 pm-11:13 am

1 stop21h 43m

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

6:28 pm-4:12 pm

2 stops19h 44m

$653

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sat 2/14

4:41 pm-12:18 pm

2 stops22h 37m

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

6:28 pm-6:37 pm

2 stops22h 09m

$674

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sun 2/8

11:35 am-9:42 pm

1 stop13h 07m

Santa Ana J. Wayne/Orange Cnty

Sun 2/15

3:45 pm-2:45 pm

2 stops20h 00m

$695

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sat 2/7

8:55 am-8:42 pm

2 stops14h 47m

Santa Ana J. Wayne/Orange Cnty

Sat 2/14

6:35 pm-5:07 pm

3 stops19h 32m

$717

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 1/20

8:55 am-9:42 pm

1 stop15h 47m

Santa Ana J. Wayne/Orange Cnty

Sat 1/24

8:00 am-7:38 pm

1 stop8h 38m

$726

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 1/20

4:41 pm-1:11 pm

2 stops23h 30m

Santa Ana J. Wayne/Orange Cnty

Sat 1/24

6:25 pm-5:07 pm

2 stops19h 42m

$730

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 1/20

8:55 am-9:42 pm

1 stop15h 47m

Santa Ana J. Wayne/Orange Cnty

Sat 1/24

8:00 am-7:38 pm

1 stop8h 38m

$747

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sun 2/8

4:41 pm-12:15 pm

2 stops22h 34m

Santa Ana J. Wayne/Orange Cnty

Sun 2/15

3:45 pm-2:45 pm

2 stops20h 00m

$1,431

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 1/20

4:41 pm-8:42 pm

2 stops31h 01m

$381

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sat 2/14

5:50 pm-6:22 pm

3 stops51h 32m

$400

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from Panama to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Panama to Santa Ana, California is on a Tuesday. Travelers who choose to depart for Santa Ana, California on a Tuesday will often find tickets for as low as $646. The most expensive day to fly to Santa Ana, California is Monday, with ticket prices averaging around $754.

Cheap Panama to Santa Ana, California flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Santa Ana, California

Fastest flight time

21h 43m

Direct flights

None
The fastest flight from Panama to Santa Ana, California takes 21h 43m
There are no direct flights from Panama to Santa Ana, California. There are no popular flight routes from Panama to Santa Ana, California.
Search flight deals

  • When did momondo last update prices for flights from Panama to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Panama to Santa Ana J. Wayne/Orange Cnty Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Panama to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Santa Ana?

Finding the right flight to Santa Ana from Panama is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Ana quick and easy, saving you time and money.

Can I find flights from Panama to Santa Ana with flexible booking policies on momondo?

Yes. All flights to Santa Ana from Panama on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama to Santa Ana?

momondo provides multiple filters to help you find the best flight to Santa Ana from Panama. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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