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Cheap flights from Panama to Los Angeles from $488

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Los Angeles departing on 12/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Panama to Los Angeles

Recent round-trip flight deals from Panama to Los Angeles

Enter your travel dates to find the best prices.
United Airlines Logo
3:30 pm - 2:03 pm
PTY
-
SNA
24h 33m
1 stop
United Airlines Logo
7:45 am - 6:37 pm
SNA
-
PTY
8h 52m
1 stop
$810United Airlines
Tue, Jul 21 - Tue, Jul 28
United Airlines Logo
3:30 pm - 11:02 am
PTY
-
SNA
21h 32m
1 stop
United Airlines Logo
3:10 pm - 2:14 pm
SNA
-
PTY
21h 04m
1 stop
$821United Airlines
Fri, Aug 21 - Sun, Aug 30
United Airlines Logo
3:30 pm - 3:13 pm
PTY
-
SNA
25h 43m
2 stops
United Airlines Logo
6:26 pm - 1:45 pm
SNA
-
PTY
17h 19m
2 stops
$831United Airlines
Fri, Oct 23 - Mon, Oct 26
Copa Airlines Logo
7:55 am - 9:45 pm
PTY
-
SNA
15h 50m
1 stop
Copa Airlines Logo
7:45 am - 6:37 pm
SNA
-
PTY
8h 52m
1 stop
$868Copa Airlines
Tue, Jul 21 - Tue, Jul 28
Copa Airlines Logo
10:00 am - 9:51 pm
PTY
-
SNA
13h 51m
1 stop
Copa Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m
1 stop
$873Copa Airlines
Sat, Oct 10 - Tue, Oct 20
Copa Airlines Logo
3:30 pm - 2:02 pm
PTY
-
SNA
24h 32m
1 stop
Copa Airlines Logo
8:00 am - 6:37 pm
SNA
-
PTY
8h 37m
1 stop
$897Copa Airlines
Tue, Sep 15 - Sat, Sep 19
Copa Airlines Logo
3:30 pm - 2:02 pm
PTY
-
SNA
24h 32m
1 stop
Copa Airlines Logo
8:13 am - 6:37 pm
SNA
-
PTY
8h 24m
1 stop
$905Copa Airlines
Sun, Aug 23 - Sat, Aug 29
Copa Airlines Logo
3:30 pm - 11:02 am
PTY
-
SNA
21h 32m
1 stop
Copa Airlines Logo
12:06 pm - 2:14 pm
SNA
-
PTY
24h 08m
1 stop
$912Copa Airlines
Mon, Aug 31 - Fri, Sep 4
United Airlines Logo
7:55 am - 10:01 pm
PTY
-
SNA
16h 06m
2 stops
United Airlines Logo
6:26 pm - 2:14 pm
SNA
-
PTY
17h 48m
2 stops
$913United Airlines
Mon, Jul 13 - Wed, Jul 15
Copa Airlines Logo
7:55 am - 9:45 pm
PTY
-
SNA
15h 50m
1 stop
Copa Airlines Logo
8:13 am - 6:37 pm
SNA
-
PTY
8h 24m
1 stop
$914Copa Airlines
Wed, Jul 15 - Wed, Aug 26

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Copa Airlines flights from Panama to Santa Ana, California

Our best Copa Airlines deals on Panama to Santa Ana, California flight tickets
Copa Airlines
Jul 21
PTY7:55 amPanama City Tocumen Intl
15h 50m
1 stop
SNA9:45 pmSanta Ana J. Wayne/Orange Cnty
Jul 28
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 52m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$868
Copa Airlines
Oct 10
PTY10:00 amPanama City Tocumen Intl
13h 51m
1 stop
SNA9:51 pmSanta Ana J. Wayne/Orange Cnty
Oct 20
SNA8:00 amSanta Ana J. Wayne/Orange Cnty
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$873
Copa Airlines
Aug 25
PTY3:30 pmPanama City Tocumen Intl
24h 32m
1 stop
SNA2:02 pmSanta Ana J. Wayne/Orange Cnty
Sep 2
SNA8:13 amSanta Ana J. Wayne/Orange Cnty
8h 24m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$878

United Airlines flights from Panama to Santa Ana, California

Our best United Airlines deals on Panama to Santa Ana, California flight tickets
United Airlines
Jul 21
PTY3:30 pmPanama City Tocumen Intl
24h 33m
1 stop
SNA2:03 pmSanta Ana J. Wayne/Orange Cnty
Jul 28
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 52m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$810
United Airlines
Aug 21
PTY3:30 pmPanama City Tocumen Intl
26h 00m
2 stops
SNA3:30 pmSanta Ana J. Wayne/Orange Cnty
Aug 30
SNA2:55 pmSanta Ana J. Wayne/Orange Cnty
21h 19m
2 stops
PTY2:14 pmPanama City Tocumen Intl
$821
United Airlines
Oct 23
PTY10:00 amPanama City Tocumen Intl
13h 51m
1 stop
SNA9:51 pmSanta Ana J. Wayne/Orange Cnty
Oct 26
SNA6:30 pmSanta Ana J. Wayne/Orange Cnty
22h 08m
2 stops
PTY6:38 pmPanama City Tocumen Intl
$831

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 22, 2026.
Use the filters below to find and compare flights from Panama to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 7/21

3:30 pm-2:03 pm

1 stop24h 33m

Santa Ana J. Wayne/Orange Cnty

Tue 7/28

7:45 am-6:37 pm

1 stop8h 52m

$810

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Fri 8/21

3:30 pm-11:02 am

1 stop21h 32m

Santa Ana J. Wayne/Orange Cnty

Sun 8/30

3:10 pm-2:14 pm

1 stop21h 04m

$821

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Fri 10/23

3:30 pm-3:13 pm

2 stops25h 43m

Santa Ana J. Wayne/Orange Cnty

Mon 10/26

6:26 pm-1:45 pm

2 stops17h 19m

$831

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 7/21

7:55 am-9:45 pm

1 stop15h 50m

Santa Ana J. Wayne/Orange Cnty

Tue 7/28

7:45 am-6:37 pm

1 stop8h 52m

$868
Quickest round-trip

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sat 10/10

10:00 am-9:51 pm

1 stop13h 51m

Santa Ana J. Wayne/Orange Cnty

Tue 10/20

8:00 am-6:37 pm

1 stop8h 37m

$873

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Tue 9/15

3:30 pm-2:02 pm

1 stop24h 32m

Santa Ana J. Wayne/Orange Cnty

Sat 9/19

8:00 am-6:37 pm

1 stop8h 37m

$897

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Sun 8/23

3:30 pm-2:02 pm

1 stop24h 32m

Santa Ana J. Wayne/Orange Cnty

Sat 8/29

8:13 am-6:37 pm

1 stop8h 24m

$905

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Mon 8/31

3:30 pm-11:02 am

1 stop21h 32m

Santa Ana J. Wayne/Orange Cnty

Fri 9/4

12:06 pm-2:14 pm

1 stop24h 08m

$912

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Mon 7/13

7:55 am-10:01 pm

2 stops16h 06m

Santa Ana J. Wayne/Orange Cnty

Wed 7/15

6:26 pm-2:14 pm

2 stops17h 48m

$913

Panama CitySanta Ana

PTY - SNA

PTYSNA

Panama City Tocumen Intl

Wed 7/15

7:55 am-9:45 pm

1 stop15h 50m

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

8:13 am-6:37 pm

1 stop8h 24m

$914

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from Panama to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Panama to Santa Ana J. Wayne/Orange Cnty?

United Airlines and Copa Airlines are the most popular carriers operating from Panama to Santa Ana J. Wayne/Orange Cnty

What airlines fly to Santa Ana, California?

Copa Airlines, Avianca and United Airlines are the top three most popular airlines that fly to Santa Ana, California from Panama according to our data. Copa Airlines is the first choice among our users, with 73% of people opting to fly with this airline when traveling to Santa Ana, California. Keep in mind that there are 3 different airlines that fly to Santa Ana, California on a routine basis, so you have a few additional options to choose from.

Cheap Panama to Santa Ana, California flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Santa Ana, California

Fastest flight time

13h 18m

Direct flights

None
The fastest flight from Panama to Santa Ana, California takes 13h 18m
There are no direct flights from Panama to Santa Ana, California. There are no popular flight routes from Panama to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from Panama to Santa Ana, California

  • When did momondo last update prices for flights from Panama to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Panama to Santa Ana J. Wayne/Orange Cnty Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Panama to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Santa Ana?

Finding the right flight to Santa Ana from Panama is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Ana quick and easy, saving you time and money.

Can I find flights from Panama to Santa Ana with flexible booking policies on momondo?

Yes. All flights to Santa Ana from Panama on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama to Santa Ana?

momondo provides multiple filters to help you find the best flight to Santa Ana from Panama. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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