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Cheap flights from Palermo to San Francisco from $328

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Palermo to San Francisco departing on 5/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
ITA Airways Logo
6:10 am - 1:15 pm
PMO
-
SFO
16h 05m
1 stop
ITA Airways Logo
3:15 pm - 10:30 am
SFO
-
PMO
34h 15m
1 stop
$567ITA Airways
Sat, Apr 18 - Sat, Apr 25
ITA Airways Logo
7:05 pm - 1:15 pm
PMO
-
SFO
27h 10m
1 stop
ITA Airways Logo
3:15 pm - 6:20 pm
SFO
-
PMO
18h 05m
1 stop
$596ITA Airways
Thu, Apr 23 - Sun, Apr 26
ITA Airways Logo
7:05 pm - 1:15 pm
PMO
-
SFO
27h 10m
1 stop
ITA Airways Logo
3:15 pm - 11:05 pm
SFO
-
PMO
22h 50m
1 stop
$599ITA Airways
Thu, Apr 23 - Sun, Apr 26
ITA Airways Logo
6:10 am - 6:57 pm
PMO
-
SFO
21h 47m
2 stops
ITA Airways Logo
8:49 am - 11:05 pm
SFO
-
PMO
29h 16m
2 stops
$602ITA Airways
Thu, Apr 23 - Sun, Apr 26
ITA Airways Logo
7:20 am - 6:57 pm
PMO
-
SFO
20h 37m
2 stops
ITA Airways Logo
8:49 am - 11:05 pm
SFO
-
PMO
29h 16m
2 stops
$605ITA Airways
Thu, Apr 23 - Sun, Apr 26
Multiple Airlines Logo
12:05 pm - 11:51 pm
PMO
-
SFO
20h 46m
2 stops
Multiple Airlines Logo
4:35 pm - 6:40 pm
SFO
-
PMO
17h 05m
1 stop
$644Multiple Airlines
Sun, Apr 19 - Sun, Apr 26
American Airlines Logo
12:05 pm - 11:51 pm
PMO
-
SFO
20h 46m
2 stops
American Airlines Logo
10:06 am - 6:40 pm
SFO
-
PMO
23h 34m
2 stops
$645American Airlines
Thu, Apr 23 - Sun, Apr 26
ITA Airways Logo
6:10 am - 1:15 pm
PMO
-
SFO
16h 05m
1 stop
ITA Airways Logo
10:10 am - 10:30 pm
SFO
-
PMO
27h 20m
2 stops
$649ITA Airways
Wed, Apr 8 - Sun, Apr 12
Multiple Airlines Logo
3:10 pm - 1:15 pm
PMO
-
SFO
31h 05m
1 stop
Multiple Airlines Logo
9:20 am - 3:25 pm
SFO
-
PMO
21h 05m
2 stops
$657Multiple Airlines
Mon, May 4 - Mon, May 11
Multiple Airlines Logo
4:10 pm - 5:12 pm
PMO
-
SFO
34h 02m
2 stops
Multiple Airlines Logo
9:20 am - 3:25 pm
SFO
-
PMO
21h 05m
2 stops
$661Multiple Airlines
Mon, May 4 - Mon, May 11

ITA Airways flights from Palermo to San Francisco

Our best ITA Airways deals on Palermo to San Francisco flight tickets
ITA Airways
Mar 30
PMO11:15 amPalermo Punta Raisi
35h 00m
1 stop
SFO1:15 pmSan Francisco
Apr 7
SFO3:15 pmSan Francisco
34h 15m
1 stop
PMO10:30 amPalermo Punta Raisi
$556
ITA Airways
Mar 30
PMO11:15 amPalermo Punta Raisi
35h 00m
1 stop
SFO1:15 pmSan Francisco
Apr 7
SFO3:15 pmSan Francisco
34h 15m
1 stop
PMO10:30 amPalermo Punta Raisi
$559
ITA Airways
Apr 18
PMO6:10 amPalermo Punta Raisi
16h 05m
1 stop
SFO1:15 pmSan Francisco
Apr 25
SFO3:15 pmSan Francisco
34h 15m
1 stop
PMO10:30 amPalermo Punta Raisi
$567

British Airways flights from Palermo to San Francisco

Our best British Airways deals on Palermo to San Francisco flight tickets
British Airways
Mar 30
PMO7:50 pmPalermo Punta Raisi
32h 57m
2 stops
SFO7:47 pmSan Francisco
Apr 7
SFO11:15 amSan Francisco
38h 55m
2 stops
PMO11:10 amPalermo Punta Raisi
$788
British Airways
Mar 30
PMO7:50 pmPalermo Punta Raisi
30h 50m
1 stop
SFO5:40 pmSan Francisco
Apr 7
SFO3:52 pmSan Francisco
34h 18m
2 stops
PMO11:10 amPalermo Punta Raisi
$875
British Airways
Mar 30
PMO7:50 pmPalermo Punta Raisi
27h 00m
1 stop
SFO1:50 pmSan Francisco
Apr 7
SFO4:35 pmSan Francisco
33h 35m
1 stop
PMO11:10 amPalermo Punta Raisi
$1,144

momondo Fare Finder

 
Customize your flight search to find flights from Palermo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Palermo to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sat 4/18

6:10 am-1:15 pm

1 stop16h 05m

San Francisco

Sat 4/25

3:15 pm-10:30 am

1 stop34h 15m

$567

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

7:05 pm-1:15 pm

1 stop27h 10m

San Francisco

Sun 4/26

3:15 pm-6:20 pm

1 stop18h 05m

$596

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

7:05 pm-1:15 pm

1 stop27h 10m

San Francisco

Sun 4/26

3:15 pm-11:05 pm

1 stop22h 50m

$599

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

6:10 am-6:57 pm

2 stops21h 47m

San Francisco

Sun 4/26

8:49 am-11:05 pm

2 stops29h 16m

$602

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

7:20 am-6:57 pm

2 stops20h 37m

San Francisco

Sun 4/26

8:49 am-11:05 pm

2 stops29h 16m

$605
Quickest round-trip

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sun 4/19

12:05 pm-11:51 pm

2 stops20h 46m

San Francisco

Sun 4/26

4:35 pm-6:40 pm

1 stop17h 05m

$644

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

12:05 pm-11:51 pm

2 stops20h 46m

San Francisco

Sun 4/26

10:06 am-6:40 pm

2 stops23h 34m

$645

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Wed 4/8

6:10 am-1:15 pm

1 stop16h 05m

San Francisco

Sun 4/12

10:10 am-10:30 pm

2 stops27h 20m

$649

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 5/4

3:10 pm-1:15 pm

1 stop31h 05m

San Francisco

Mon 5/11

9:20 am-3:25 pm

2 stops21h 05m

$657

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 5/4

4:10 pm-5:12 pm

2 stops34h 02m

San Francisco

Mon 5/11

9:20 am-3:25 pm

2 stops21h 05m

$661

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Palermo to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Palermo to San Francisco flights?

You could potentially save up to 4% on your flight if you consider stops on a Palermo to San Francisco flight.

When to book flights from Palermo to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Palermo to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Palermo to San Francisco (PMO to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Palermo to San Francisco

Fastest flight time

16h 05m

Direct flights

None
The fastest flight from Palermo to San Francisco takes 16h 05m
There are no direct flights from Palermo to San Francisco. There are no popular flight routes from Palermo to San Francisco.
Search flight deals

  • How far is Palermo Punta Raisi to San Francisco by plane?

    San Francisco is 6480.7 mi away from Palermo Punta Raisi. A reasonable flight in good conditions will take 16h 05m.

  • When did momondo last update prices for flights from Palermo Punta Raisi Airport to San Francisco Airport?

    Prices for flights from Palermo Punta Raisi Airport to San Francisco Airport were last updated today.

  • How old do you have to be to fly from Palermo Punta Raisi Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Palermo Punta Raisi Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Walnut Creek
Roseville
Hayward
Berkeley
Santa Clara
Big Sur
Fremont
Calistoga
Vallejo
Salinas
Daly City
Half Moon Bay
Milpitas
South San Francisco
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Palermo to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Palermo to San Francisco for you.

Can I find flights from Palermo to San Francisco with flexible booking policies on momondo?

All flight searches from Palermo to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Palermo to San Francisco?

momondo provides multiple filters to help you find the best flight to San Francisco from Palermo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Palermo to San Francisco right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Palermo to San Francisco now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Francisco and let you know when they change.

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