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Cheap flights from Palermo to San Francisco from $418

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Palermo to San Francisco departing on 3/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
ITA Airways Logo
7:05 pm - 1:15 pm
PMO
-
SFO
27h 10m
1 stop
ITA Airways Logo
12:05 pm - 3:25 pm
SFO
-
PMO
18h 20m
2 stops
$560ITA Airways
Thu, Apr 23 - Wed, May 6
ITA Airways Logo
2:25 pm - 1:05 pm
PMO
-
SFO
31h 40m
1 stop
ITA Airways Logo
4:05 pm - 6:25 pm
SFO
-
PMO
18h 20m
1 stop
$562ITA Airways
Sun, Mar 1 - Mon, Mar 9
ITA Airways Logo
3:15 pm - 1:05 pm
PMO
-
SFO
30h 50m
1 stop
ITA Airways Logo
4:05 pm - 6:25 pm
SFO
-
PMO
18h 20m
1 stop
$568ITA Airways
Sun, Mar 1 - Mon, Mar 9
Multiple Airlines Logo
9:10 am - 11:45 am
PMO
-
SFO
35h 35m
1 stop
Multiple Airlines Logo
8:10 pm - 12:05 pm
SFO
-
PMO
30h 55m
1 stop
$605Multiple Airlines
Thu, Apr 23 - Wed, May 6
ITA Airways Logo
8:30 pm - 1:15 pm
PMO
-
SFO
25h 45m
1 stop
ITA Airways Logo
3:15 pm - 6:20 pm
SFO
-
PMO
18h 05m
1 stop
$610ITA Airways
Thu, Apr 23 - Sun, Apr 26
ITA Airways Logo
7:05 pm - 1:15 pm
PMO
-
SFO
27h 10m
1 stop
ITA Airways Logo
3:15 pm - 6:20 pm
SFO
-
PMO
18h 05m
1 stop
$611ITA Airways
Thu, Apr 23 - Sun, Apr 26
American Airlines Logo
12:05 pm - 11:54 pm
PMO
-
SFO
20h 49m
2 stops
American Airlines Logo
7:10 am - 6:40 pm
SFO
-
PMO
26h 30m
2 stops
$614American Airlines
Thu, Apr 23 - Sun, Apr 26
American Airlines Logo
12:05 pm - 9:56 am
PMO
-
SFO
30h 51m
2 stops
American Airlines Logo
1:28 pm - 6:40 pm
SFO
-
PMO
20h 12m
2 stops
$615American Airlines
Thu, Apr 23 - Sun, Apr 26
ITA Airways Logo
7:20 am - 5:12 pm
PMO
-
SFO
18h 52m
2 stops
ITA Airways Logo
3:15 pm - 10:30 pm
SFO
-
PMO
22h 15m
1 stop
$616ITA Airways
Thu, Apr 23 - Sun, Apr 26
British Airways Logo
12:05 pm - 11:51 pm
PMO
-
SFO
20h 46m
2 stops
British Airways Logo
4:35 pm - 6:40 pm
SFO
-
PMO
17h 05m
1 stop
$617British Airways
Thu, Apr 23 - Sun, Apr 26

ITA Airways flights from Palermo to San Francisco

Our best ITA Airways deals on Palermo to San Francisco flight tickets
ITA Airways
Apr 23
PMO7:05 pmPalermo Punta Raisi
27h 10m
1 stop
SFO1:15 pmSan Francisco
May 6
SFO12:05 pmSan Francisco
18h 20m
2 stops
PMO3:25 pmPalermo Punta Raisi
$560
ITA Airways
Mar 1
PMO2:25 pmPalermo Punta Raisi
31h 40m
1 stop
SFO1:05 pmSan Francisco
Mar 9
SFO4:05 pmSan Francisco
18h 20m
1 stop
PMO6:25 pmPalermo Punta Raisi
$562
ITA Airways
Apr 23
PMO8:30 pmPalermo Punta Raisi
25h 45m
1 stop
SFO1:15 pmSan Francisco
Apr 26
SFO3:15 pmSan Francisco
18h 05m
1 stop
PMO6:20 pmPalermo Punta Raisi
$610

British Airways flights from Palermo to San Francisco

Our best British Airways deals on Palermo to San Francisco flight tickets
British Airways
Apr 23
PMO12:05 pmPalermo Punta Raisi
20h 46m
2 stops
SFO11:51 pmSan Francisco
Apr 26
SFO4:35 pmSan Francisco
17h 05m
1 stop
PMO6:40 pmPalermo Punta Raisi
$617
British Airways
Mar 1
PMO8:30 pmPalermo Punta Raisi
27h 30m
1 stop
SFO3:00 pmSan Francisco
Mar 9
SFO11:35 pmSan Francisco
51h 10m
2 stops
PMO10:45 amPalermo Punta Raisi
$635
British Airways
Mar 30
PMO7:50 pmPalermo Punta Raisi
27h 00m
1 stop
SFO1:50 pmSan Francisco
Apr 10
SFO1:28 pmSan Francisco
19h 27m
2 stops
PMO5:55 pmPalermo Punta Raisi
$3,364

momondo Fare Finder

 
Customize your flight search to find flights from Palermo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Palermo to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

7:05 pm-1:15 pm

1 stop27h 10m

San Francisco

Wed 5/6

12:05 pm-3:25 pm

2 stops18h 20m

$560

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sun 3/1

2:25 pm-1:05 pm

1 stop31h 40m

San Francisco

Mon 3/9

4:05 pm-6:25 pm

1 stop18h 20m

$562

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sun 3/1

3:15 pm-1:05 pm

1 stop30h 50m

San Francisco

Mon 3/9

4:05 pm-6:25 pm

1 stop18h 20m

$568

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

9:10 am-11:45 am

1 stop35h 35m

San Francisco

Wed 5/6

8:10 pm-12:05 pm

1 stop30h 55m

$605

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

8:30 pm-1:15 pm

1 stop25h 45m

San Francisco

Sun 4/26

3:15 pm-6:20 pm

1 stop18h 05m

$610

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

7:05 pm-1:15 pm

1 stop27h 10m

San Francisco

Sun 4/26

3:15 pm-6:20 pm

1 stop18h 05m

$611

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

12:05 pm-11:54 pm

2 stops20h 49m

San Francisco

Sun 4/26

7:10 am-6:40 pm

2 stops26h 30m

$614

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

12:05 pm-9:56 am

2 stops30h 51m

San Francisco

Sun 4/26

1:28 pm-6:40 pm

2 stops20h 12m

$615

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

7:20 am-5:12 pm

2 stops18h 52m

San Francisco

Sun 4/26

3:15 pm-10:30 pm

1 stop22h 15m

$616

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

12:05 pm-11:51 pm

2 stops20h 46m

San Francisco

Sun 4/26

4:35 pm-6:40 pm

1 stop17h 05m

$617

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Palermo to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Palermo to San Francisco flights?

You could potentially save up to 35% on your flight if you consider stops on a Palermo to San Francisco flight.

When to book flights from Palermo to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Palermo to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Palermo to San Francisco (PMO to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Palermo to San Francisco

Fastest flight time

21h 50m

Direct flights

None
The fastest flight from Palermo to San Francisco takes 21h 50m
There are no direct flights from Palermo to San Francisco. There are no popular flight routes from Palermo to San Francisco.
Search flight deals

  • How far is Palermo Punta Raisi to San Francisco by plane?

    San Francisco is 6480.5 mi away from Palermo Punta Raisi. A reasonable flight in good conditions will take 21h 50m.

  • When did momondo last update prices for flights from Palermo Punta Raisi Airport to San Francisco Airport?

    Prices for flights from Palermo Punta Raisi Airport to San Francisco Airport were last updated today.

  • How old do you have to be to fly from Palermo Punta Raisi Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Palermo Punta Raisi Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Calistoga
Santa Clara
Walnut Creek
Berkeley
Big Sur
Fremont
Half Moon Bay
Daly City
Salinas
Vallejo
Sunnyvale
Livermore
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Palermo to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Palermo to San Francisco for you.

Can I find flights from Palermo to San Francisco with flexible booking policies on momondo?

All flight searches from Palermo to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Palermo to San Francisco?

momondo provides multiple filters to help you find the best flight to San Francisco from Palermo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Palermo to San Francisco right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Palermo to San Francisco now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Francisco and let you know when they change.

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