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Cheap flights from Palermo to San Francisco from $409

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Palermo to San Francisco departing on 9/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Palermo to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
ITA Airways Logo
7:05 pm - 1:05 pm
PMO
-
SFO
27h 00m
1 stop
ITA Airways Logo
10:15 am - 6:20 pm
SFO
-
PMO
23h 05m
2 stops
$789ITA Airways
Fri, Nov 6 - Sun, Nov 8
ITA Airways Logo
7:05 pm - 1:05 pm
PMO
-
SFO
27h 00m
1 stop
ITA Airways Logo
10:15 am - 6:20 pm
SFO
-
PMO
23h 05m
2 stops
$790ITA Airways
Fri, Nov 6 - Sun, Nov 8
ITA Airways Logo
7:05 pm - 1:05 pm
PMO
-
SFO
27h 00m
1 stop
ITA Airways Logo
10:15 am - 6:20 pm
SFO
-
PMO
23h 05m
2 stops
$791ITA Airways
Fri, Nov 6 - Sun, Nov 8
British Airways Logo
7:50 pm - 7:28 pm
PMO
-
SFO
32h 38m
2 stops
British Airways Logo
4:35 pm - 6:40 pm
SFO
-
PMO
17h 05m
1 stop
$798British Airways
Mon, Jul 6 - Sun, Jul 12
United Airlines Logo
9:45 am - 9:38 pm
PMO
-
SFO
20h 53m
2 stops
United Airlines Logo
12:45 am - 7:15 am
SFO
-
PMO
21h 30m
2 stops
$803United Airlines
Mon, Jul 6 - Sat, Jul 11
ITA Airways Logo
8:25 pm - 1:05 pm
PMO
-
SFO
25h 40m
2 stops
ITA Airways Logo
10:15 am - 6:20 pm
SFO
-
PMO
23h 05m
2 stops
$854ITA Airways
Fri, Nov 6 - Sun, Nov 8
ITA Airways Logo
8:25 pm - 1:05 pm
PMO
-
SFO
25h 40m
2 stops
ITA Airways Logo
10:15 am - 6:20 pm
SFO
-
PMO
23h 05m
2 stops
$901ITA Airways
Fri, Nov 6 - Sun, Nov 8
ITA Airways Logo
8:25 pm - 1:05 pm
PMO
-
SFO
25h 40m
2 stops
ITA Airways Logo
10:15 am - 6:20 pm
SFO
-
PMO
23h 05m
2 stops
$902ITA Airways
Fri, Nov 6 - Sun, Nov 8
United Airlines Logo
7:55 am - 7:25 pm
PMO
-
SFO
20h 30m
1 stop
United Airlines Logo
6:56 pm - 7:15 am
SFO
-
PMO
27h 19m
2 stops
$963United Airlines
Tue, Jul 7 - Sat, Jul 11
Multiple Airlines Logo
2:45 pm - 4:15 pm
PMO
-
SFO
34h 30m
3 stops
Multiple Airlines Logo
7:35 pm - 12:50 pm
SFO
-
PMO
32h 15m
3 stops
$1,085Multiple Airlines
Mon, Jul 6 - Sun, Jul 12

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ITA Airways flights from Palermo to San Francisco

Our best ITA Airways deals on Palermo to San Francisco flight tickets
ITA Airways
Nov 6
PMO7:05 pmPalermo Punta Raisi
27h 00m
1 stop
SFO1:05 pmSan Francisco
Nov 8
SFO10:15 amSan Francisco
23h 05m
2 stops
PMO6:20 pmPalermo Punta Raisi
$789
ITA Airways
Nov 6
PMO7:05 pmPalermo Punta Raisi
27h 00m
1 stop
SFO1:05 pmSan Francisco
Nov 8
SFO10:15 amSan Francisco
23h 05m
2 stops
PMO6:20 pmPalermo Punta Raisi
$790
ITA Airways
Nov 6
PMO7:05 pmPalermo Punta Raisi
27h 00m
1 stop
SFO1:05 pmSan Francisco
Nov 8
SFO10:15 amSan Francisco
23h 05m
2 stops
PMO6:20 pmPalermo Punta Raisi
$791

United Airlines flights from Palermo to San Francisco

Our best United Airlines deals on Palermo to San Francisco flight tickets
United Airlines
Jul 6
PMO9:45 amPalermo Punta Raisi
20h 53m
2 stops
SFO9:38 pmSan Francisco
Jul 11
SFO12:45 amSan Francisco
21h 30m
2 stops
PMO7:15 amPalermo Punta Raisi
$803
United Airlines
Jun 25
PMO9:45 amPalermo Punta Raisi
24h 30m
2 stops
SFO1:15 amSan Francisco
Jul 2
SFO12:50 amSan Francisco
21h 25m
2 stops
PMO7:15 amPalermo Punta Raisi
$804
United Airlines
Jun 25
PMO9:45 amPalermo Punta Raisi
22h 11m
2 stops
SFO10:56 pmSan Francisco
Jul 3
SFO6:10 amSan Francisco
16h 05m
1 stop
PMO7:15 amPalermo Punta Raisi
$837

momondo Fare Finder

 
Customize your flight search to find flights from Palermo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Palermo to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 11/6

7:05 pm-1:05 pm

1 stop27h 00m

San Francisco

Sun 11/8

10:15 am-6:20 pm

2 stops23h 05m

$789

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 11/6

7:05 pm-1:05 pm

1 stop27h 00m

San Francisco

Sun 11/8

10:15 am-6:20 pm

2 stops23h 05m

$790

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 11/6

7:05 pm-1:05 pm

1 stop27h 00m

San Francisco

Sun 11/8

10:15 am-6:20 pm

2 stops23h 05m

$791

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 7/6

7:50 pm-7:28 pm

2 stops32h 38m

San Francisco

Sun 7/12

4:35 pm-6:40 pm

1 stop17h 05m

$798
Quickest round-trip

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 7/6

9:45 am-9:38 pm

2 stops20h 53m

San Francisco

Sat 7/11

12:45 am-7:15 am

2 stops21h 30m

$803

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 11/6

8:25 pm-1:05 pm

2 stops25h 40m

San Francisco

Sun 11/8

10:15 am-6:20 pm

2 stops23h 05m

$854

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 11/6

8:25 pm-1:05 pm

2 stops25h 40m

San Francisco

Sun 11/8

10:15 am-6:20 pm

2 stops23h 05m

$901

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 11/6

8:25 pm-1:05 pm

2 stops25h 40m

San Francisco

Sun 11/8

10:15 am-6:20 pm

2 stops23h 05m

$902

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Tue 7/7

7:55 am-7:25 pm

1 stop20h 30m

San Francisco

Sat 7/11

6:56 pm-7:15 am

2 stops27h 19m

$963

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 7/6

2:45 pm-4:15 pm

3 stops34h 30m

San Francisco

Sun 7/12

7:35 pm-12:50 pm

3 stops32h 15m

$1,085

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Palermo to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Palermo to San Francisco flights?

You could potentially save up to 30% on your flight if you consider stops on a Palermo to San Francisco flight.

When to book flights from Palermo to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Palermo to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Palermo to San Francisco (PMO to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Palermo to San Francisco

Fastest flight time

20h 30m

Direct flights

None
The fastest flight from Palermo to San Francisco takes 20h 30m
There are no direct flights from Palermo to San Francisco. There are no popular flight routes from Palermo to San Francisco.
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Frequently asked questions about flying from Palermo to San Francisco

  • How far is Palermo Punta Raisi to San Francisco by plane?

    San Francisco is 6480.7 mi away from Palermo Punta Raisi. A reasonable flight in good conditions will take 20h 30m.

  • When did momondo last update prices for flights from Palermo Punta Raisi Airport to San Francisco Airport?

    Prices for flights from Palermo Punta Raisi Airport to San Francisco Airport were last updated today.

  • How old do you have to be to fly from Palermo Punta Raisi Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Palermo Punta Raisi Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Bodega Bay
Sonoma
Fremont
Hayward
Roseville
South San Francisco
Walnut Creek
Berkeley
Santa Clara
Vallejo
Salinas
Sunnyvale
Big Sur
Daly City
Burlingame
Milpitas
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Palermo to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Palermo to San Francisco for you.

Can I find flights from Palermo to San Francisco with flexible booking policies on momondo?

All flight searches from Palermo to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Palermo to San Francisco?

momondo provides multiple filters to help you find the best flight to San Francisco from Palermo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Palermo to San Francisco right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Palermo to San Francisco now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Francisco and let you know when they change.

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