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Cheap flights from Palermo to San Francisco from $628

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Palermo to San Francisco departing on 11/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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Lufthansa Logo
12:10 pm - 7:35 pmPMO-SFO
16h 25m1 stop
Lufthansa Logo
8:30 am - 11:05 amSFO-PMO
17h 35m2 stops
$628Lufthansa
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Fri, Nov 21 - Wed, Nov 26
Lufthansa Logo
12:15 pm - 12:40 pmPMO-SFO
33h 25m1 stop
Lufthansa Logo
8:30 am - 11:05 amSFO-PMO
17h 35m2 stops
$635Lufthansa
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Thu, Nov 20 - Wed, Nov 26
ITA Airways Logo
7:05 pm - 5:47 pmPMO-SFO
31h 42m2 stops
ITA Airways Logo
10:52 am - 11:00 pmSFO-PMO
27h 08m2 stops
$637ITA Airways
Find Deal
Sat, Jan 17 - Sun, Jan 25
ITA Airways Logo
7:05 pm - 6:52 pmPMO-SFO
32h 47m2 stops
ITA Airways Logo
9:10 am - 2:30 pmSFO-PMO
20h 20m2 stops
$638ITA Airways
Find Deal
Sat, Jan 17 - Sun, Jan 25
American Airlines Logo
1:55 pm - 3:00 pmPMO-SFO
34h 05m1 stop
American Airlines Logo
11:59 pm - 10:45 amSFO-PMO
50h 46m2 stops
$679American Airlines
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Thu, Mar 5 - Mon, Mar 9
Multiple Airlines Logo
6:10 am - 5:45 pmPMO-SFO
20h 35m2 stops
Multiple Airlines Logo
11:00 am - 2:30 pmSFO-PMO
18h 30m2 stops
$684Multiple Airlines
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Fri, Feb 13 - Sat, Feb 28
American Airlines Logo
1:55 pm - 6:45 pmPMO-SFO
37h 50m1 stop
American Airlines Logo
5:00 pm - 10:45 amSFO-PMO
57h 45m2 stops
$685American Airlines
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Thu, Mar 5 - Mon, Mar 9
Turkish Airlines Logo
9:30 am - 4:45 pmPMO-SFO
40h 15m1 stop
Turkish Airlines Logo
6:50 pm - 5:45 pmSFO-PMO
37h 55m1 stop
$757Turkish Airlines
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Mon, Nov 17 - Fri, Nov 28
Multiple Airlines Logo
12:25 pm - 2:45 pmPMO-SFO
35h 20m3 stops
Multiple Airlines Logo
4:35 pm - 11:55 pmSFO-PMO
22h 20m2 stops
$852Multiple Airlines
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Fri, Feb 13 - Sat, Feb 28
Turkish Airlines Logo
9:30 am - 4:45 pmPMO-SFO
40h 15m1 stop
Turkish Airlines Logo
6:50 pm - 5:45 pmSFO-PMO
37h 55m1 stop
$856Turkish Airlines
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Mon, Nov 17 - Mon, Nov 24

ITA Airways flights from Palermo to San Francisco

Our best ITA Airways deals on Palermo to San Francisco flight tickets
ITA Airways
Jan 17
PMO7:05 pmPalermo Punta Raisi
31h 42m
2 stops
SFO5:47 pmSan Francisco
Jan 25
SFO10:52 amSan Francisco
27h 08m
2 stops
PMO11:00 pmPalermo Punta Raisi
$637
Find similar
ITA Airways
Jan 17
PMO7:05 pmPalermo Punta Raisi
32h 47m
2 stops
SFO6:52 pmSan Francisco
Jan 25
SFO9:10 amSan Francisco
20h 20m
2 stops
PMO2:30 pmPalermo Punta Raisi
$638
Find similar
ITA Airways
Nov 18
PMO7:10 pmPalermo Punta Raisi
35h 40m
2 stops
SFO9:50 pmSan Francisco
Nov 27
SFO3:05 pmSan Francisco
22h 55m
1 stop
PMO11:00 pmPalermo Punta Raisi
$648
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American Airlines flights from Palermo to San Francisco

Our best American Airlines deals on Palermo to San Francisco flight tickets
American Airlines
Mar 5
PMO1:55 pmPalermo Punta Raisi
34h 05m
1 stop
SFO3:00 pmSan Francisco
Mar 9
SFO11:59 pmSan Francisco
50h 46m
2 stops
PMO10:45 amPalermo Punta Raisi
$679
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American Airlines
Mar 5
PMO1:55 pmPalermo Punta Raisi
37h 50m
1 stop
SFO6:45 pmSan Francisco
Mar 9
SFO5:00 pmSan Francisco
57h 45m
2 stops
PMO10:45 amPalermo Punta Raisi
$685
Find similar
American Airlines
Nov 20
PMO3:05 pmPalermo Punta Raisi
35h 16m
2 stops
SFO5:21 pmSan Francisco
Nov 28
SFO2:06 pmSan Francisco
36h 54m
2 stops
PMO12:00 pmPalermo Punta Raisi
$729
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momondo Fare Finder

 
Customize your flight search to find flights from Palermo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Palermo to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 11/21

12:10 pm-7:35 pm

1 stop16h 25m

San Francisco

Wed 11/26

8:30 am-11:05 am

2 stops17h 35m

$628

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 11/20

12:15 pm-12:40 pm

1 stop33h 25m

San Francisco

Wed 11/26

8:30 am-11:05 am

2 stops17h 35m

$635

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sat 1/17

7:05 pm-5:47 pm

2 stops31h 42m

San Francisco

Sun 1/25

10:52 am-11:00 pm

2 stops27h 08m

$637

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sat 1/17

7:05 pm-6:52 pm

2 stops32h 47m

San Francisco

Sun 1/25

9:10 am-2:30 pm

2 stops20h 20m

$638

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 3/5

1:55 pm-3:00 pm

1 stop34h 05m

San Francisco

Mon 3/9

11:59 pm-10:45 am

2 stops50h 46m

$679

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 2/13

6:10 am-5:45 pm

2 stops20h 35m

San Francisco

Sat 2/28

11:00 am-2:30 pm

2 stops18h 30m

$684

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 3/5

1:55 pm-6:45 pm

1 stop37h 50m

San Francisco

Mon 3/9

5:00 pm-10:45 am

2 stops57h 45m

$685

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 11/17

9:30 am-4:45 pm

1 stop40h 15m

San Francisco

Fri 11/28

6:50 pm-5:45 pm

1 stop37h 55m

$757

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 2/13

12:25 pm-2:45 pm

3 stops35h 20m

San Francisco

Sat 2/28

4:35 pm-11:55 pm

2 stops22h 20m

$852

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 11/17

9:30 am-4:45 pm

1 stop40h 15m

San Francisco

Mon 11/24

6:50 pm-5:45 pm

1 stop37h 55m

$856

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Palermo to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Palermo to San Francisco is on a Tuesday when prices can be found for as low as $605. The most expensive day to fly to San Francisco is Thursday, with ticket prices averaging around $795.

Can stopping save me money on Palermo to San Francisco flights?

You could potentially save up to 19% on your flight if you consider stops on a Palermo to San Francisco flight.

When to book flights from Palermo to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Palermo to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Palermo to San Francisco (PMO to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Palermo to San Francisco

Direct flights

None
There are no direct flights from Palermo to San Francisco. There are no popular flight routes from Palermo to San Francisco.
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  • How far is Palermo Punta Raisi to San Francisco by plane?

    San Francisco is 6480.5 mi away from Palermo Punta Raisi. A reasonable flight in good conditions will take 15h 55m.

  • When did momondo last update prices for flights from Palermo Punta Raisi Airport to San Francisco Airport?

    Prices for flights from Palermo Punta Raisi Airport to San Francisco Airport were last updated today.

  • How old do you have to be to fly from Palermo Punta Raisi Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Palermo Punta Raisi Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Calistoga
Hayward
Big Sur
Santa Clara
Daly City
Fremont
Berkeley
Vallejo
Walnut Creek
Half Moon Bay
Salinas
Turlock
Livermore
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Palermo to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Palermo to San Francisco for you.

Can I find flights from Palermo to San Francisco with flexible booking policies on momondo?

All flight searches from Palermo to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Palermo to San Francisco?

momondo provides multiple filters to help you find the best flight to San Francisco from Palermo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Palermo to San Francisco right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Palermo to San Francisco now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Francisco and let you know when they change.

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