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Cheap flights from Palermo to San Francisco from $425

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Palermo to San Francisco departing on 6/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Palermo to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
ITA Airways Logo
3:10 pm - 1:15 pm
PMO
-
SFO
31h 05m
1 stop
ITA Airways Logo
3:15 pm - 6:20 pm
SFO
-
PMO
18h 05m
1 stop
$564ITA Airways
Mon, May 18 - Tue, May 26
ITA Airways Logo
6:10 am - 1:15 pm
PMO
-
SFO
16h 05m
1 stop
ITA Airways Logo
3:15 pm - 3:25 pm
SFO
-
PMO
15h 10m
1 stop
$626ITA Airways
Wed, Oct 14 - Sun, Oct 18
ITA Airways Logo
6:10 am - 1:15 pm
PMO
-
SFO
16h 05m
1 stop
ITA Airways Logo
3:15 pm - 7:45 pm
SFO
-
PMO
19h 30m
1 stop
$627ITA Airways
Wed, Oct 14 - Sun, Oct 18
ITA Airways Logo
6:10 am - 1:15 pm
PMO
-
SFO
16h 05m
1 stop
ITA Airways Logo
3:15 pm - 7:45 pm
SFO
-
PMO
19h 30m
1 stop
$629ITA Airways
Wed, Oct 14 - Sun, Oct 18
British Airways Logo
7:50 pm - 1:50 pm
PMO
-
SFO
27h 00m
1 stop
British Airways Logo
10:07 am - 11:10 am
SFO
-
PMO
40h 03m
2 stops
$636British Airways
Mon, May 18 - Tue, May 26
British Airways Logo
7:50 pm - 5:40 pm
PMO
-
SFO
30h 50m
2 stops
British Airways Logo
10:07 am - 11:10 am
SFO
-
PMO
40h 03m
2 stops
$641British Airways
Mon, May 18 - Tue, May 26
ITA Airways Logo
7:45 pm - 1:15 pm
PMO
-
SFO
26h 30m
2 stops
ITA Airways Logo
3:15 pm - 10:30 pm
SFO
-
PMO
22h 15m
1 stop
$654ITA Airways
Mon, May 18 - Tue, May 26
ITA Airways Logo
7:45 pm - 1:15 pm
PMO
-
SFO
26h 30m
2 stops
ITA Airways Logo
3:15 pm - 6:20 pm
SFO
-
PMO
18h 05m
1 stop
$704ITA Airways
Mon, May 18 - Tue, May 26
British Airways Logo
7:50 pm - 1:50 pm
PMO
-
SFO
27h 00m
1 stop
British Airways Logo
4:35 pm - 11:10 am
SFO
-
PMO
33h 35m
1 stop
$719British Airways
Fri, Oct 2 - Tue, Oct 6
British Airways Logo
12:40 pm - 12:43 am
PMO
-
SFO
21h 03m
2 stops
British Airways Logo
1:59 pm - 6:40 pm
SFO
-
PMO
19h 41m
2 stops
$721British Airways
Wed, Oct 14 - Sun, Oct 18

ITA Airways flights from Palermo to San Francisco

Our best ITA Airways deals on Palermo to San Francisco flight tickets
ITA Airways
May 18
PMO3:10 pmPalermo Punta Raisi
31h 05m
1 stop
SFO1:15 pmSan Francisco
May 26
SFO3:15 pmSan Francisco
18h 05m
1 stop
PMO6:20 pmPalermo Punta Raisi
$564
ITA Airways
May 12
PMO6:10 amPalermo Punta Raisi
16h 05m
1 stop
SFO1:15 pmSan Francisco
May 17
SFO3:15 pmSan Francisco
22h 15m
1 stop
PMO10:30 pmPalermo Punta Raisi
$583
ITA Airways
May 13
PMO8:30 pmPalermo Punta Raisi
25h 45m
1 stop
SFO1:15 pmSan Francisco
May 17
SFO3:15 pmSan Francisco
18h 05m
1 stop
PMO6:20 pmPalermo Punta Raisi
$605

United Airlines flights from Palermo to San Francisco

Our best United Airlines deals on Palermo to San Francisco flight tickets
United Airlines
Jul 9
PMO9:45 amPalermo Punta Raisi
34h 34m
2 stops
SFO11:19 amSan Francisco
Jul 17
SFO9:00 pmSan Francisco
49h 15m
2 stops
PMO7:15 amPalermo Punta Raisi
$893
United Airlines
Jul 10
PMO7:55 amPalermo Punta Raisi
20h 30m
1 stop
SFO7:25 pmSan Francisco
Jul 18
SFO6:56 pmSan Francisco
27h 19m
2 stops
PMO7:15 amPalermo Punta Raisi
$981
United Airlines
Jul 10
PMO7:55 amPalermo Punta Raisi
21h 42m
2 stops
SFO8:37 pmSan Francisco
Jul 14
SFO12:50 amSan Francisco
21h 25m
2 stops
PMO7:15 amPalermo Punta Raisi
$987

momondo Fare Finder

 
Customize your flight search to find flights from Palermo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 8, 2026.
Use the filters below to find and compare flights from Palermo to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 5/18

3:10 pm-1:15 pm

1 stop31h 05m

San Francisco

Tue 5/26

3:15 pm-6:20 pm

1 stop18h 05m

$564
Quickest round-trip

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Wed 10/14

6:10 am-1:15 pm

1 stop16h 05m

San Francisco

Sun 10/18

3:15 pm-3:25 pm

1 stop15h 10m

$626

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Wed 10/14

6:10 am-1:15 pm

1 stop16h 05m

San Francisco

Sun 10/18

3:15 pm-7:45 pm

1 stop19h 30m

$627

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Wed 10/14

6:10 am-1:15 pm

1 stop16h 05m

San Francisco

Sun 10/18

3:15 pm-7:45 pm

1 stop19h 30m

$629

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 5/18

7:50 pm-1:50 pm

1 stop27h 00m

San Francisco

Tue 5/26

10:07 am-11:10 am

2 stops40h 03m

$636

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 5/18

7:50 pm-5:40 pm

2 stops30h 50m

San Francisco

Tue 5/26

10:07 am-11:10 am

2 stops40h 03m

$641

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 5/18

7:45 pm-1:15 pm

2 stops26h 30m

San Francisco

Tue 5/26

3:15 pm-10:30 pm

1 stop22h 15m

$654

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 5/18

7:45 pm-1:15 pm

2 stops26h 30m

San Francisco

Tue 5/26

3:15 pm-6:20 pm

1 stop18h 05m

$704

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 10/2

7:50 pm-1:50 pm

1 stop27h 00m

San Francisco

Tue 10/6

4:35 pm-11:10 am

1 stop33h 35m

$719

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Wed 10/14

12:40 pm-12:43 am

2 stops21h 03m

San Francisco

Sun 10/18

1:59 pm-6:40 pm

2 stops19h 41m

$721

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Palermo to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Palermo to San Francisco flights?

You could potentially save up to 16% on your flight if you consider stops on a Palermo to San Francisco flight.

When to book flights from Palermo to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Palermo to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Palermo to San Francisco (PMO to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Palermo to San Francisco

Fastest flight time

15h 55m

Direct flights

None
The fastest flight from Palermo to San Francisco takes 15h 55m
There are no direct flights from Palermo to San Francisco. There are no popular flight routes from Palermo to San Francisco.
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Frequently asked questions about flying from Palermo to San Francisco

  • How far is Palermo Punta Raisi to San Francisco by plane?

    San Francisco is 6480.7 mi away from Palermo Punta Raisi. A reasonable flight in good conditions will take 15h 55m.

  • When did momondo last update prices for flights from Palermo Punta Raisi Airport to San Francisco Airport?

    Prices for flights from Palermo Punta Raisi Airport to San Francisco Airport were last updated today.

  • How old do you have to be to fly from Palermo Punta Raisi Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Palermo Punta Raisi Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Walnut Creek
Roseville
Berkeley
Hayward
Santa Clara
Fremont
Vallejo
Big Sur
Calistoga
Sunnyvale
South San Francisco
Salinas
Daly City
Half Moon Bay
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Palermo to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Palermo to San Francisco for you.

Can I find flights from Palermo to San Francisco with flexible booking policies on momondo?

All flight searches from Palermo to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Palermo to San Francisco?

momondo provides multiple filters to help you find the best flight to San Francisco from Palermo. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Palermo to San Francisco right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Palermo to San Francisco now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to San Francisco and let you know when they change.

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