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Cheap flights from Myrtle Beach to San Francisco from $153

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
2:10 pm - 10:09 pmMYR  Myrtle Beach Intl-SFO San Francisco
10h 59m1 stop Charlotte Douglas
American Airlines Logo
12:42 pm - 10:52 pmSFO  San Francisco-MYR Myrtle Beach Intl
7h 10m1 stop Dallas/Fort Worth
$369American Airlines
Tue, Oct 27 - Wed, Oct 28
American Airlines Logo
7:25 am - 3:10 pmMYR  Myrtle Beach Intl-SFO San Francisco
10h 45m1 stop Dallas/Fort Worth
American Airlines Logo
1:29 pm - 11:55 pmSFO  San Francisco-MYR Myrtle Beach Intl
7h 26m1 stop Charlotte Douglas
$380American Airlines
Thu, Dec 31 - Tue, Jan 5
Delta Logo
10:55 am - 5:11 pmMYR  Myrtle Beach Intl-SFO San Francisco
9h 16m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 5:55 pmSFO  San Francisco-MYR Myrtle Beach Intl
8h 55m1 stop Atlanta Hartsfield-Jackson
$380Delta
Fri, Jan 22 - Thu, Jan 28
Southwest Logo
10:55 am - 3:30 pmMYR  Myrtle Beach Intl-SFO San Francisco
7h 35m1 stop Nashville Intl
Southwest Logo
9:25 pm - 9:50 amSFO  San Francisco-MYR Myrtle Beach Intl
9h 25m1 stop Baltimore/Washington
$380Southwest
Thu, Jan 14 - Fri, Jan 15
Delta Logo
6:59 pm - 11:55 pmMYR  Myrtle Beach Intl-SFO San Francisco
7h 56m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:00 pm - 10:01 amSFO  San Francisco-MYR Myrtle Beach Intl
9h 01m1 stop Atlanta Hartsfield-Jackson
$382Delta
Wed, Dec 16 - Tue, Dec 29
American Airlines Logo
6:18 pm - 11:08 pmMYR  Myrtle Beach Intl-SFO San Francisco
7h 50m1 stop Charlotte Douglas
American Airlines Logo
10:09 pm - 9:46 amSFO  San Francisco-MYR Myrtle Beach Intl
8h 37m1 stop Charlotte Douglas
$385American Airlines
Thu, Dec 31 - Tue, Jan 5
Southwest Logo
8:00 am - 2:20 pmMYR  Myrtle Beach Intl-SFO San Francisco
9h 20m1 stop Baltimore/Washington
Southwest Logo
7:00 pm - 10:00 amSFO  San Francisco-MYR Myrtle Beach Intl
12h 00m2 stops San Diego Baltimore/Washington
$396Southwest
Fri, Jan 22 - Thu, Jan 28
Southwest Logo
10:55 am - 8:30 pmMYR  Myrtle Beach Intl-SFO San Francisco
12h 35m2 stops Nashville Intl Phoenix Sky Harbor Intl
Southwest Logo
9:25 pm - 9:50 amSFO  San Francisco-MYR Myrtle Beach Intl
9h 25m1 stop Baltimore/Washington
$396Southwest
Thu, Jan 14 - Fri, Jan 15
United Airlines Logo
5:00 pm - 12:30 amMYR  Myrtle Beach Intl-SFO San Francisco
10h 30m1 stop Chicago O'Hare Intl
United Airlines Logo
9:15 pm - 9:42 amSFO  San Francisco-MYR Myrtle Beach Intl
9h 27m1 stop Newark
$461United Airlines
Fri, Oct 2 - Tue, Oct 6
United Airlines Logo
11:27 am - 7:30 amMYR  Myrtle Beach Intl-SFO San Francisco
23h 03m2 stops Newark Los Angeles Los Angeles
United Airlines Logo
11:59 pm - 10:21 amSFO  San Francisco-MYR Myrtle Beach Intl
8h 22m1 stop Newark
$491United Airlines
Wed, Oct 28 - Sat, Oct 31

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American Airlines flights from Myrtle Beach to San Francisco

Our best American Airlines deals on Myrtle Beach to San Francisco flight tickets
American Airlines
Oct 27
MYR2:10 pmMyrtle Beach Intl
10h 59m
1 stop
SFO10:09 pmSan Francisco
Oct 28
SFO12:42 pmSan Francisco
7h 10m
1 stop
MYR10:52 pmMyrtle Beach Intl
$369
American Airlines
Dec 31
MYR7:25 amMyrtle Beach Intl
10h 45m
1 stop
SFO3:10 pmSan Francisco
Jan 5
SFO1:29 pmSan Francisco
7h 26m
1 stop
MYR11:55 pmMyrtle Beach Intl
$380
American Airlines
Dec 31
MYR6:18 pmMyrtle Beach Intl
7h 50m
1 stop
SFO11:08 pmSan Francisco
Jan 5
SFO10:09 pmSan Francisco
8h 37m
1 stop
MYR9:46 amMyrtle Beach Intl
$385

Delta flights from Myrtle Beach to San Francisco

Our best Delta deals on Myrtle Beach to San Francisco flight tickets
Delta
Dec 16
MYR6:59 pmMyrtle Beach Intl
7h 56m
1 stop
SFO11:55 pmSan Francisco
Dec 29
SFO10:00 pmSan Francisco
9h 01m
1 stop
MYR10:01 amMyrtle Beach Intl
$382
Delta
Oct 8
MYR6:58 pmMyrtle Beach Intl
7h 58m
1 stop
SFO11:56 pmSan Francisco
Oct 12
SFO10:25 pmSan Francisco
8h 42m
1 stop
MYR10:07 amMyrtle Beach Intl
$419
Delta
Dec 17
MYR6:59 pmMyrtle Beach Intl
8h 06m
1 stop
SFO12:05 amSan Francisco
Dec 29
SFO10:00 pmSan Francisco
9h 01m
1 stop
MYR10:01 amMyrtle Beach Intl
$425

momondo Fare Finder

 
Use the filters below to find and compare flights from Myrtle Beach to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Tue 10/27

2:10 pm-10:09 pm

1 stop10h 59m

San Francisco

Wed 10/28

12:42 pm-10:52 pm

1 stop7h 10m

$369

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Thu 12/31

7:25 am-3:10 pm

1 stop10h 45m

San Francisco

Tue 1/5

1:29 pm-11:55 pm

1 stop7h 26m

$380

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Fri 1/22

10:55 am-5:11 pm

1 stop9h 16m

San Francisco

Thu 1/28

6:00 am-5:55 pm

1 stop8h 55m

$380

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Thu 1/14

10:55 am-3:30 pm

1 stop7h 35m

San Francisco

Fri 1/15

9:25 pm-9:50 am

1 stop9h 25m

$380

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Wed 12/16

6:59 pm-11:55 pm

1 stop7h 56m

San Francisco

Tue 12/29

10:00 pm-10:01 am

1 stop9h 01m

$382
Quickest round-trip

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Thu 12/31

6:18 pm-11:08 pm

1 stop7h 50m

San Francisco

Tue 1/5

10:09 pm-9:46 am

1 stop8h 37m

$385

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Fri 1/22

8:00 am-2:20 pm

1 stop9h 20m

San Francisco

Thu 1/28

7:00 pm-10:00 am

2 stops12h 00m

$396

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Thu 1/14

10:55 am-8:30 pm

2 stops12h 35m

San Francisco

Fri 1/15

9:25 pm-9:50 am

1 stop9h 25m

$396

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Fri 10/2

5:00 pm-12:30 am

1 stop10h 30m

San Francisco

Tue 10/6

9:15 pm-9:42 am

1 stop9h 27m

$461

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Wed 10/28

11:27 am-7:30 am

2 stops23h 03m

San Francisco

Sat 10/31

11:59 pm-10:21 am

1 stop8h 22m

$491

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Myrtle Beach to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and San Francisco?

Prices are currently low for flights on this route.

Typical prices usually range from $434 to $778.
The lowest price recently found on this route was $369.

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of August, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $466.

How have Myrtle Beach to San Francisco flight prices changed over time?

As of September 2026, prices for Myrtle Beach to San Francisco flights are approximately 18% cheaper when compared to flights at the same time last year.

When to book flights from Myrtle Beach to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to San Francisco (MYR to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to San Francisco

Best Price Found

$153

Fastest flight time

7h 35m

Direct flights

None
The best one-way flight to San Francisco from Myrtle Beach in the past 72 hours is $153. The best round-trip flight deal from Myrtle Beach to San Francisco found on momondo in the last 72 hours is $369.
The fastest flight from Myrtle Beach to San Francisco takes 7h 35m
There are no direct flights from Myrtle Beach to San Francisco. There are no popular flight routes from Myrtle Beach to San Francisco.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to San Francisco

  • How far is Myrtle Beach Intl to San Francisco by plane?

    The straight-line distance from Myrtle Beach Intl to San Francisco is 2433.2 mi. In terms of flight time, this usually takes a little over 7h 35m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to San Francisco Airport?

    Prices for flights from Myrtle Beach Intl Airport to San Francisco Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to San Francisco Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to San Francisco?

Best airlines flying from Myrtle Beach to San Francisco

Compare and see reviews for airlines that fly from Myrtle Beach to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $336Free CancellationRating
8.0
4,192 reviews
Search Southwest flights
DeltaPriceFrom $359Free CancellationRating
7.8
8,591 reviews
Search Delta flights
American AirlinesPriceFrom $362Free CancellationRating
7.0
12,073 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Berkeley
Hayward
Bodega Bay
Fremont
Santa Clara
Walnut Creek
Sunnyvale
Vallejo
Half Moon Bay
Roseville
Salinas
Sonoma
Daly City
Milpitas
Pacific Grove
Marina

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to San Francisco?

Finding the right flight to San Francisco from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Myrtle Beach.

I’m not ready to book a flight from Myrtle Beach to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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