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Cheap flights from Myrtle Beach to San Francisco from $182

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to San Francisco departing on 9/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:15 pm - 7:18 pm
MYR
-
SFO
10h 03m
1 stop
American Airlines Logo
11:40 pm - 12:31 pm
SFO
-
MYR
9h 51m
1 stop
$363American Airlines
Sat, Aug 15 - Sat, Aug 22
Southwest Logo
1:40 pm - 8:35 pm
MYR
-
SFO
9h 55m
1 stop
Southwest Logo
11:40 pm - 2:10 pm
SFO
-
MYR
11h 30m
2 stops
$368Southwest
Sat, Aug 15 - Sat, Aug 22
Southwest Logo
2:25 pm - 10:05 pm
MYR
-
SFO
10h 40m
2 stops
Southwest Logo
7:55 pm - 10:05 am
SFO
-
MYR
11h 10m
2 stops
$373Southwest
Wed, Sep 23 - Tue, Sep 29
Southwest Logo
2:35 pm - 10:25 pm
MYR
-
SFO
10h 50m
2 stops
Southwest Logo
3:45 pm - 9:50 am
SFO
-
MYR
15h 05m
2 stops
$379Southwest
Wed, Oct 7 - Sat, Oct 24
American Airlines Logo
4:23 pm - 10:18 pm
MYR
-
SFO
8h 55m
1 stop
American Airlines Logo
11:03 pm - 9:46 am
SFO
-
MYR
7h 43m
1 stop
$380American Airlines
Sat, Sep 5 - Mon, Sep 14
Southwest Logo
2:25 pm - 10:20 pm
MYR
-
SFO
10h 55m
2 stops
Southwest Logo
10:30 pm - 10:05 am
SFO
-
MYR
8h 35m
1 stop
$385Southwest
Tue, Aug 4 - Tue, Aug 11
Southwest Logo
8:15 am - 4:25 pm
MYR
-
SFO
11h 10m
2 stops
Southwest Logo
7:55 pm - 10:05 am
SFO
-
MYR
11h 10m
2 stops
$390Southwest
Tue, Aug 4 - Tue, Aug 11
American Airlines Logo
12:14 pm - 7:18 pm
MYR
-
SFO
10h 04m
1 stop
American Airlines Logo
8:00 am - 8:59 pm
SFO
-
MYR
9h 59m
1 stop
$397American Airlines
Thu, Aug 27 - Mon, Aug 31
American Airlines Logo
4:43 pm - 10:28 pm
MYR
-
SFO
8h 45m
1 stop
American Airlines Logo
6:30 am - 6:51 pm
SFO
-
MYR
9h 21m
1 stop
$398American Airlines
Tue, Aug 4 - Tue, Aug 11
American Airlines Logo
4:23 pm - 10:18 pm
MYR
-
SFO
8h 55m
1 stop
American Airlines Logo
11:40 pm - 11:24 am
SFO
-
MYR
8h 44m
1 stop
$400American Airlines
Thu, Sep 3 - Sun, Sep 6

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United Airlines flights from Myrtle Beach to San Francisco

Our best United Airlines deals on Myrtle Beach to San Francisco flight tickets
United Airlines
Sep 2
MYR10:23 amMyrtle Beach Intl
10h 12m
1 stop
SFO5:35 pmSan Francisco
Sep 30
SFO9:30 pmSan Francisco
9h 14m
1 stop
MYR9:44 amMyrtle Beach Intl
$473
United Airlines
Nov 17
MYR11:30 amMyrtle Beach Intl
11h 14m
1 stop
SFO7:44 pmSan Francisco
Nov 18
SFO9:30 pmSan Francisco
9h 50m
1 stop
MYR10:20 amMyrtle Beach Intl
$525
United Airlines
Nov 17
MYR11:30 amMyrtle Beach Intl
23h 00m
2 stops
SFO7:30 amSan Francisco
Nov 18
SFO9:30 pmSan Francisco
9h 50m
1 stop
MYR10:20 amMyrtle Beach Intl
$582

American Airlines flights from Myrtle Beach to San Francisco

Our best American Airlines deals on Myrtle Beach to San Francisco flight tickets
American Airlines
Aug 15
MYR12:15 pmMyrtle Beach Intl
10h 03m
1 stop
SFO7:18 pmSan Francisco
Aug 22
SFO11:40 pmSan Francisco
9h 51m
1 stop
MYR12:31 pmMyrtle Beach Intl
$363
American Airlines
Sep 5
MYR4:23 pmMyrtle Beach Intl
8h 55m
1 stop
SFO10:18 pmSan Francisco
Sep 14
SFO11:03 pmSan Francisco
7h 43m
1 stop
MYR9:46 amMyrtle Beach Intl
$380
American Airlines
Aug 27
MYR12:14 pmMyrtle Beach Intl
10h 04m
1 stop
SFO7:18 pmSan Francisco
Aug 31
SFO8:00 amSan Francisco
9h 59m
1 stop
MYR8:59 pmMyrtle Beach Intl
$397

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Myrtle Beach to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 8/15

12:15 pm-7:18 pm

1 stop10h 03m

San Francisco

Sat 8/22

11:40 pm-12:31 pm

1 stop9h 51m

$363

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 8/15

1:40 pm-8:35 pm

1 stop9h 55m

San Francisco

Sat 8/22

11:40 pm-2:10 pm

2 stops11h 30m

$368

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Wed 9/23

2:25 pm-10:05 pm

2 stops10h 40m

San Francisco

Tue 9/29

7:55 pm-10:05 am

2 stops11h 10m

$373

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Wed 10/7

2:35 pm-10:25 pm

2 stops10h 50m

San Francisco

Sat 10/24

3:45 pm-9:50 am

2 stops15h 05m

$379
Quickest round-trip

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 9/5

4:23 pm-10:18 pm

1 stop8h 55m

San Francisco

Mon 9/14

11:03 pm-9:46 am

1 stop7h 43m

$380

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Tue 8/4

2:25 pm-10:20 pm

2 stops10h 55m

San Francisco

Tue 8/11

10:30 pm-10:05 am

1 stop8h 35m

$385

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Tue 8/4

8:15 am-4:25 pm

2 stops11h 10m

San Francisco

Tue 8/11

7:55 pm-10:05 am

2 stops11h 10m

$390

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Thu 8/27

12:14 pm-7:18 pm

1 stop10h 04m

San Francisco

Mon 8/31

8:00 am-8:59 pm

1 stop9h 59m

$397

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Tue 8/4

4:43 pm-10:28 pm

1 stop8h 45m

San Francisco

Tue 8/11

6:30 am-6:51 pm

1 stop9h 21m

$398

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Thu 9/3

4:23 pm-10:18 pm

1 stop8h 55m

San Francisco

Sun 9/6

11:40 pm-11:24 am

1 stop8h 44m

$400

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Myrtle Beach to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of October, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $433.

How have Myrtle Beach to San Francisco flight prices changed over time?

As of June 2026, prices for Myrtle Beach to San Francisco flights are approximately 2% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to San Francisco (MYR to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to San Francisco

Fastest flight time

7h 45m

Direct flights

None
The fastest flight from Myrtle Beach to San Francisco takes 7h 45m
There are no direct flights from Myrtle Beach to San Francisco. There are no popular flight routes from Myrtle Beach to San Francisco.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to San Francisco

  • How far is Myrtle Beach Intl to San Francisco by plane?

    The straight-line distance from Myrtle Beach Intl to San Francisco is 2433.2 mi. In terms of flight time, this usually takes a little over 7h 45m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to San Francisco Airport?

    Prices for flights from Myrtle Beach Intl Airport to San Francisco Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to San Francisco Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to San Francisco?

Best airlines flying from Myrtle Beach to San Francisco

Compare and see reviews for airlines that fly from Myrtle Beach to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $312Free CancellationRating
7.1
11,746 reviews
Search American Airlines flights
DeltaPriceFrom $312Free CancellationRating
7.8
8,424 reviews
Search Delta flights
SouthwestPriceFrom $382Free CancellationRating
7.9
4,242 reviews
Search Southwest flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Bodega Bay
Sonoma
Fremont
Hayward
Roseville
South San Francisco
Walnut Creek
Berkeley
Santa Clara
Vallejo
Salinas
Sunnyvale
Big Sur
Daly City
Burlingame
Milpitas
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to San Francisco?

Finding the right flight to San Francisco from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Myrtle Beach.

I’m not ready to book a flight from Myrtle Beach to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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