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Cheap flights from Myrtle Beach to San Francisco from $169

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to San Francisco departing on 9/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:56 pm - 6:08 pm-
7h 12m
American Airlines Logo
9:53 pm - 8:35 am-
7h 42m
$337American Airlines
Wed, Sep 16 - Sat, Sep 26
American Airlines Logo
8:08 am - 3:39 pm-
10h 31m
American Airlines Logo
9:53 pm - 10:33 am-
9h 40m
$337American Airlines
Sat, Sep 12 - Sat, Sep 19
United Airlines Logo
3:24 pm - 9:10 pm-
8h 46m
United Airlines Logo
11:14 pm - 9:44 am-
7h 30m
$337United Airlines
Sat, Aug 29 - Sat, Sep 5
Southwest Logo
1:40 pm - 8:35 pm-
9h 55m
Southwest Logo
11:40 pm - 2:10 pm-
11h 30m
$342Southwest
Sat, Sep 12 - Sat, Sep 19
Southwest Logo
9:55 am - 4:50 pm-
9h 55m
Southwest Logo
11:40 pm - 3:00 pm-
12h 20m
$342Southwest
Sat, Aug 29 - Sat, Sep 5
American Airlines Logo
8:08 am - 3:39 pm-
10h 31m
American Airlines Logo
11:03 pm - 11:20 am-
9h 17m
$365American Airlines
Sat, Sep 12 - Mon, Sep 14
Delta Logo
6:56 pm - 11:57 pm-
8h 01m
Delta Logo
10:59 pm - 10:36 am-
8h 37m
$368Delta
Thu, Sep 17 - Tue, Sep 22
Delta Logo
6:58 pm - 11:57 pm-
7h 59m
Delta Logo
9:55 pm - 10:07 am-
9h 12m
$368Delta
Tue, Sep 29 - Sat, Oct 3
United Airlines Logo
5:00 pm - 12:30 am-
10h 30m
United Airlines Logo
9:15 pm - 11:38 am-
11h 23m
$447United Airlines
Thu, Oct 1 - Mon, Oct 5
Multiple Airlines Logo
9:40 pm - 12:02 pm-
17h 22m
Multiple Airlines Logo
7:30 pm - 11:39 am-
13h 09m
$459Multiple Airlines
Mon, Aug 17 - Fri, Aug 21

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American Airlines flights from Myrtle Beach to San Francisco

Our best American Airlines deals on Myrtle Beach to San Francisco flight tickets
American Airlines
Sep 12
MYR8:08 amMyrtle Beach Intl
10h 31m
1 stop
SFO3:39 pmSan Francisco
Sep 14
SFO11:03 pmSan Francisco
9h 17m
1 stop
MYR11:20 amMyrtle Beach Intl
$365
American Airlines
Sep 16
MYR5:01 pmMyrtle Beach Intl
9h 27m
1 stop
SFO11:28 pmSan Francisco
Sep 26
SFO9:29 amSan Francisco
10h 24m
2 stops
MYR10:53 pmMyrtle Beach Intl
$382
American Airlines
Sep 16
MYR1:56 pmMyrtle Beach Intl
7h 12m
1 stop
SFO6:08 pmSan Francisco
Sep 26
SFO9:53 pmSan Francisco
7h 42m
1 stop
MYR8:35 amMyrtle Beach Intl
$383

United Airlines flights from Myrtle Beach to San Francisco

Our best United Airlines deals on Myrtle Beach to San Francisco flight tickets
United Airlines
Aug 29
MYR3:24 pmMyrtle Beach Intl
8h 46m
1 stop
SFO9:10 pmSan Francisco
Sep 5
SFO11:14 pmSan Francisco
7h 30m
1 stop
MYR9:44 amMyrtle Beach Intl
$337
United Airlines
Oct 1
MYR5:00 pmMyrtle Beach Intl
10h 30m
1 stop
SFO12:30 amSan Francisco
Oct 5
SFO9:15 pmSan Francisco
11h 23m
1 stop
MYR11:38 amMyrtle Beach Intl
$447
United Airlines
Oct 1
MYR5:00 pmMyrtle Beach Intl
10h 30m
1 stop
SFO12:30 amSan Francisco
Oct 5
SFO9:15 pmSan Francisco
9h 27m
1 stop
MYR9:42 amMyrtle Beach Intl
$493

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from Myrtle Beach to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Wed 9/16

1:56 pm-6:08 pm

1 stop7h 12m

San Francisco

Sat 9/26

9:53 pm-8:35 am

1 stop7h 42m

$337

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 9/12

8:08 am-3:39 pm

1 stop10h 31m

San Francisco

Sat 9/19

9:53 pm-10:33 am

1 stop9h 40m

$337

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 8/29

3:24 pm-9:10 pm

1 stop8h 46m

San Francisco

Sat 9/5

11:14 pm-9:44 am

1 stop7h 30m

$337

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 9/12

1:40 pm-8:35 pm

1 stop9h 55m

San Francisco

Sat 9/19

11:40 pm-2:10 pm

2 stops11h 30m

$342

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 8/29

9:55 am-4:50 pm

1 stop9h 55m

San Francisco

Sat 9/5

11:40 pm-3:00 pm

2 stops12h 20m

$342

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 9/12

8:08 am-3:39 pm

1 stop10h 31m

San Francisco

Mon 9/14

11:03 pm-11:20 am

1 stop9h 17m

$365

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Thu 9/17

6:56 pm-11:57 pm

1 stop8h 01m

San Francisco

Tue 9/22

10:59 pm-10:36 am

1 stop8h 37m

$368

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Tue 9/29

6:58 pm-11:57 pm

1 stop7h 59m

San Francisco

Sat 10/3

9:55 pm-10:07 am

1 stop9h 12m

$368

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Thu 10/1

5:00 pm-12:30 am

1 stop10h 30m

San Francisco

Mon 10/5

9:15 pm-11:38 am

1 stop11h 23m

$447

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Mon 8/17

9:40 pm-12:02 pm

1 stop17h 22m

San Francisco

Fri 8/21

7:30 pm-11:39 am

2 stops13h 09m

$459

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Myrtle Beach to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of October, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $446.

How have Myrtle Beach to San Francisco flight prices changed over time?

As of August 2026, prices for Myrtle Beach to San Francisco flights are approximately 30% cheaper when compared to flights at the same time last year.

When to book flights from Myrtle Beach to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to San Francisco (MYR to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to San Francisco

Fastest flight time

7h 12m

Direct flights

None
The fastest flight from Myrtle Beach to San Francisco takes 7h 12m
There are no direct flights from Myrtle Beach to San Francisco. There are no popular flight routes from Myrtle Beach to San Francisco.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to San Francisco

  • How far is Myrtle Beach Intl to San Francisco by plane?

    The straight-line distance from Myrtle Beach Intl to San Francisco is 2433.2 mi. In terms of flight time, this usually takes a little over 7h 12m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to San Francisco Airport?

    Prices for flights from Myrtle Beach Intl Airport to San Francisco Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to San Francisco Airport?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Myrtle Beach to San Francisco?

Best airlines flying from Myrtle Beach to San Francisco

Compare and see reviews for airlines that fly from Myrtle Beach to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $326Free CancellationRating
7.8
8,481 reviews
Search Delta flights
American AirlinesPriceFrom $362Free CancellationRating
7.1
11,848 reviews
Search American Airlines flights
SouthwestPriceFrom $382Free CancellationRating
8.0
4,222 reviews
Search Southwest flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
South San Francisco
Fremont
Berkeley
Hayward
Walnut Creek
Bodega Bay
Roseville
Sonoma
Santa Clara
Vallejo
Salinas
Sunnyvale
Milpitas
Daly City
Burlingame
Turlock
Marina

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to San Francisco?

Finding the right flight to San Francisco from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Myrtle Beach which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Myrtle Beach to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Myrtle Beach.

I’m not ready to book a flight from Myrtle Beach to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Myrtle Beach are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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