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Cheap flights from Missouri to Los Angeles from $80

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Los Angeles departing on 4/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
7:00 am - 3:42 pm
MCI
-
SNA
10h 42m
1 stop
Spirit Airlines Logo
4:37 pm - 11:33 pm
SNA
-
MCI
4h 56m
1 stop
$178Spirit Airlines
Wed, Apr 22 - Sat, Apr 25
Spirit Airlines Logo
7:00 am - 12:25 pm
MCI
-
SNA
7h 25m
1 stop
Spirit Airlines Logo
6:45 am - 5:09 pm
SNA
-
MCI
8h 24m
1 stop
$184Spirit Airlines
Mon, Mar 9 - Fri, Mar 13
Multiple Airlines Logo
12:14 pm - 12:25 pm
STL
-
SNA
26h 11m
1 stop
Multiple Airlines Logo
1:12 pm - 12:15 pm
SNA
-
STL
21h 03m
1 stop
$195Multiple Airlines
Mon, Mar 9 - Mon, Mar 16
Spirit Airlines Logo
7:00 am - 3:42 pm
MCI
-
SNA
10h 42m
1 stop
Spirit Airlines Logo
7:45 am - 11:33 pm
SNA
-
MCI
13h 48m
1 stop
$197Spirit Airlines
Tue, Apr 21 - Tue, May 5
Multiple Airlines Logo
12:14 pm - 12:25 pm
STL
-
SNA
26h 11m
1 stop
Multiple Airlines Logo
5:54 pm - 9:49 am
SNA
-
STL
37h 55m
2 stops
$209Multiple Airlines
Mon, Mar 9 - Mon, Mar 16
Frontier Logo
8:06 pm - 1:00 pm
STL
-
SNA
18h 54m
1 stop
Frontier Logo
5:42 pm - 9:48 am
SNA
-
STL
38h 06m
2 stops
$214Frontier
Thu, Mar 19 - Mon, Mar 30
American Airlines Logo
5:19 am - 12:38 pm
SGF
-
SNA
9h 19m
1 stop
American Airlines Logo
4:43 pm - 11:56 pm
SNA
-
SGF
5h 13m
1 stop
$314American Airlines
Sat, Apr 25 - Wed, Apr 29
United Airlines Logo
6:24 pm - 10:15 pm
JLN
-
SNA
5h 51m
1 stop
United Airlines Logo
6:45 am - 5:43 pm
SNA
-
JLN
8h 58m
1 stop
$325United Airlines
Wed, Mar 18 - Wed, Mar 25
United Airlines Logo
8:54 am - 10:15 pm
JLN
-
SNA
15h 21m
2 stops
United Airlines Logo
6:45 am - 5:43 pm
SNA
-
JLN
8h 58m
1 stop
$331United Airlines
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
5:19 am - 12:38 pm
SGF
-
SNA
9h 19m
1 stop
American Airlines Logo
7:45 am - 9:02 pm
SNA
-
SGF
11h 17m
1 stop
$382American Airlines
Sat, Apr 25 - Tue, Apr 28

Spirit Airlines flights from Missouri to Santa Ana

Our best Spirit Airlines deals on Missouri to Santa Ana flight tickets
Spirit Airlines
Apr 22
MCI7:00 amKansas City
10h 42m
1 stop
SNA3:42 pmSanta Ana J. Wayne/Orange Cnty
Apr 25
SNA4:37 pmSanta Ana J. Wayne/Orange Cnty
4h 56m
1 stop
MCI11:33 pmKansas City
$178
Spirit Airlines
Mar 9
MCI7:00 amKansas City
7h 25m
1 stop
SNA12:25 pmSanta Ana J. Wayne/Orange Cnty
Mar 13
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
8h 24m
1 stop
MCI5:09 pmKansas City
$184
Spirit Airlines
Apr 21
MCI7:00 amKansas City
10h 42m
1 stop
SNA3:42 pmSanta Ana J. Wayne/Orange Cnty
May 5
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
13h 48m
1 stop
MCI11:33 pmKansas City
$197

American Airlines flights from Missouri to Santa Ana

Our best American Airlines deals on Missouri to Santa Ana flight tickets
American Airlines
Mar 3
STL2:31 pmLambert-St Louis
7h 00m
1 stop
SNA7:31 pmSanta Ana J. Wayne/Orange Cnty
Mar 10
SNA8:17 amSanta Ana J. Wayne/Orange Cnty
6h 56m
1 stop
STL5:13 pmLambert-St Louis
$257
American Airlines
Apr 25
SGF5:19 amSpringfield-Branson
9h 19m
1 stop
SNA12:38 pmSanta Ana J. Wayne/Orange Cnty
Apr 29
SNA4:43 pmSanta Ana J. Wayne/Orange Cnty
5h 13m
1 stop
SGF11:56 pmSpringfield-Branson
$314
American Airlines
Mar 3
STL2:31 pmLambert-St Louis
7h 00m
1 stop
SNA7:31 pmSanta Ana J. Wayne/Orange Cnty
Mar 10
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
6h 43m
1 stop
STL3:28 pmLambert-St Louis
$333

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Missouri to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Wed 4/22

7:00 am-3:42 pm

1 stop10h 42m

Santa Ana J. Wayne/Orange Cnty

Sat 4/25

4:37 pm-11:33 pm

1 stop4h 56m

$178

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Mon 3/9

7:00 am-12:25 pm

1 stop7h 25m

Santa Ana J. Wayne/Orange Cnty

Fri 3/13

6:45 am-5:09 pm

1 stop8h 24m

$184

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 3/9

12:14 pm-12:25 pm

1 stop26h 11m

Santa Ana J. Wayne/Orange Cnty

Mon 3/16

1:12 pm-12:15 pm

1 stop21h 03m

$195

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Tue 4/21

7:00 am-3:42 pm

1 stop10h 42m

Santa Ana J. Wayne/Orange Cnty

Tue 5/5

7:45 am-11:33 pm

1 stop13h 48m

$197

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 3/9

12:14 pm-12:25 pm

1 stop26h 11m

Santa Ana J. Wayne/Orange Cnty

Mon 3/16

5:54 pm-9:49 am

2 stops37h 55m

$209

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 3/19

8:06 pm-1:00 pm

1 stop18h 54m

Santa Ana J. Wayne/Orange Cnty

Mon 3/30

5:42 pm-9:48 am

2 stops38h 06m

$214

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Sat 4/25

5:19 am-12:38 pm

1 stop9h 19m

Santa Ana J. Wayne/Orange Cnty

Wed 4/29

4:43 pm-11:56 pm

1 stop5h 13m

$314

JoplinSanta Ana

JLN - SNA

JLNSNA

Joplin

Wed 3/18

6:24 pm-10:15 pm

1 stop5h 51m

Santa Ana J. Wayne/Orange Cnty

Wed 3/25

6:45 am-5:43 pm

1 stop8h 58m

$325

JoplinSanta Ana

JLN - SNA

JLNSNA

Joplin

Wed 3/18

8:54 am-10:15 pm

2 stops15h 21m

Santa Ana J. Wayne/Orange Cnty

Wed 3/25

6:45 am-5:43 pm

1 stop8h 58m

$331

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Sat 4/25

5:19 am-12:38 pm

1 stop9h 19m

Santa Ana J. Wayne/Orange Cnty

Tue 4/28

7:45 am-9:02 pm

1 stop11h 17m

$382

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Missouri to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from Missouri is in November. Flight prices, which tend to average around $345, are often lower during this time because this is during the off-season. The month of April is another great option to travel to Santa Ana, with average flight prices from Missouri averaging around $362.

How far in advance should I book a flight to Santa Ana?

You are more likely to see cheaper flights to Santa Ana from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana for around $433 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana from Missouri for as low as $335 on momondo.

Can stopping save me money on Missouri to Santa Ana flights?

You could potentially save up to 72% on your flight if you consider stops on a Missouri to Santa Ana flight.

Cheap Missouri to Santa Ana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santa Ana

Fastest flight time

5h 01m

Direct flights

None
The fastest flight from Missouri to Santa Ana takes 5h 01m
There are no direct flights from Missouri to Santa Ana. There are no popular flight routes from Missouri to Santa Ana.
Search flight deals

  • When did momondo last update prices for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents required for your trip to Santa Ana J. Wayne/Orange Cnty Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Ana J. Wayne/Orange Cnty Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santa Ana

Compare and see reviews for airlines that fly from Missouri to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $88Free CancellationRating
6.3
8,444 reviews
Search Spirit Airlines flights
FrontierPriceFrom $126Free CancellationRating
5.7
3,052 reviews
Search Frontier flights
DeltaPriceFrom $128Free CancellationRating
7.9
8,180 reviews
Search Delta flights
United AirlinesPriceFrom $252Free CancellationRating
7.4
9,273 reviews
Search United Airlines flights
American AirlinesPriceFrom $255Free CancellationRating
7.2
11,265 reviews
Search American Airlines flights
SouthwestPriceFrom $287Free CancellationRating
8.0
4,280 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santa Ana?

Finding the right flight to Santa Ana from Missouri is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Ana quick and easy, saving you time and money.

Can I find flights from Missouri to Santa Ana with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Ana from Missouri with this policy.

How can momondo help me find flights from Missouri to Santa Ana?

momondo helps you find the best flight between Missouri and Santa Ana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Santa Ana trip

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