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Cheap flights from Missouri to Los Angeles from $111

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Los Angeles departing on 6/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Missouri to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
2:17 pm - 10:12 am
MCI
-
SNA
21h 55m
1 stop
Frontier Logo
11:07 am - 1:22 pm
SNA
-
MCI
24h 15m
1 stop
$256Frontier
Thu, Sep 17 - Mon, Sep 21
Frontier Logo
2:17 pm - 10:12 am
MCI
-
SNA
21h 55m
1 stop
Frontier Logo
4:50 pm - 1:22 pm
SNA
-
MCI
18h 32m
2 stops
$263Frontier
Wed, Oct 14 - Sun, Oct 18
Multiple Airlines Logo
12:52 pm - 9:51 am
SGF
-
SNA
22h 59m
1 stop
Multiple Airlines Logo
2:27 pm - 1:32 pm
SNA
-
SGF
21h 05m
1 stop
$304Multiple Airlines
Sat, Sep 26 - Mon, Sep 28
Delta Logo
11:38 am - 6:37 pm
SGF
-
SNA
8h 59m
1 stop
Delta Logo
6:45 am - 6:13 pm
SNA
-
SGF
9h 28m
1 stop
$315Delta
Sat, Aug 22 - Tue, Aug 25
American Airlines Logo
11:48 am - 5:29 pm
COU
-
SNA
7h 41m
1 stop
American Airlines Logo
1:34 pm - 10:27 pm
SNA
-
COU
6h 53m
1 stop
$318American Airlines
Sat, Aug 22 - Tue, Aug 25
Multiple Airlines Logo
1:12 pm - 1:32 pm
SGF
-
SNA
26h 20m
1 stop
Multiple Airlines Logo
2:27 pm - 1:32 pm
SNA
-
SGF
21h 05m
1 stop
$318Multiple Airlines
Thu, Sep 24 - Mon, Sep 28
Delta Logo
11:38 am - 10:00 pm
SGF
-
SNA
12h 22m
2 stops
Delta Logo
6:45 am - 6:13 pm
SNA
-
SGF
9h 28m
1 stop
$320Delta
Tue, Aug 18 - Tue, Aug 25
American Airlines Logo
11:48 am - 5:29 pm
COU
-
SNA
7h 41m
1 stop
American Airlines Logo
9:45 am - 9:21 pm
SNA
-
COU
9h 36m
2 stops
$324American Airlines
Sat, Aug 22 - Tue, Aug 25
United Airlines Logo
6:00 am - 12:03 pm
MCI
-
SNA
8h 03m
2 stops
United Airlines Logo
4:00 pm - 11:25 pm
SNA
-
MCI
5h 25m
1 stop
$336United Airlines
Tue, Jun 16 - Tue, Jun 23
United Airlines Logo
1:53 pm - 5:29 pm
JLN
-
SNA
5h 36m
1 stop
United Airlines Logo
4:10 pm - 11:44 pm
SNA
-
JLN
5h 34m
1 stop
$449United Airlines
Thu, Aug 20 - Mon, Aug 24

Southwest flights from Missouri to Santa Ana, California

Our best Southwest deals on Missouri to Santa Ana, California flight tickets
Southwest
Jun 30
MCI1:10 pmKansas City
7h 10m
2 stops
SNA6:20 pmSanta Ana J. Wayne/Orange Cnty
Jun 30
SNA7:50 pmSanta Ana J. Wayne/Orange Cnty
10h 55m
1 stop
MCI8:45 amKansas City
$395
Southwest
Jun 24
MCI3:25 pmKansas City
7h 45m
1 stop
SNA9:10 pmSanta Ana J. Wayne/Orange Cnty
Jun 30
SNA9:00 amSanta Ana J. Wayne/Orange Cnty
11h 00m
2 stops
MCI10:00 pmKansas City
$397
Southwest
Aug 7
MCI5:10 amKansas City
7h 40m
2 stops
SNA10:50 amSanta Ana J. Wayne/Orange Cnty
Aug 11
SNA1:00 pmSanta Ana J. Wayne/Orange Cnty
7h 30m
1 stop
MCI10:30 pmKansas City
$404

Alaska Airlines flights from Missouri to Santa Ana, California

Our best Alaska Airlines deals on Missouri to Santa Ana, California flight tickets
Alaska Airlines
May 27
MCI7:55 pmKansas City
16h 13m
1 stop
SNA10:08 amSanta Ana J. Wayne/Orange Cnty
May 29
SNA3:31 pmSanta Ana J. Wayne/Orange Cnty
20h 26m
1 stop
MCI1:57 pmKansas City
$427
Alaska Airlines
Sep 26
SGF12:47 pmSpringfield-Branson
11h 43m
2 stops
SNA10:30 pmSanta Ana J. Wayne/Orange Cnty
Sep 28
SNA7:12 pmSanta Ana J. Wayne/Orange Cnty
11h 58m
2 stops
SGF9:10 amSpringfield-Branson
$428
Alaska Airlines
Sep 5
SGF11:27 amSpringfield-Branson
13h 03m
2 stops
SNA10:30 pmSanta Ana J. Wayne/Orange Cnty
Sep 9
SNA7:12 pmSanta Ana J. Wayne/Orange Cnty
11h 58m
2 stops
SGF9:10 amSpringfield-Branson
$429

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 16, 2026.
Use the filters below to find and compare flights from Missouri to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Thu 9/17

2:17 pm-10:12 am

1 stop21h 55m

Santa Ana J. Wayne/Orange Cnty

Mon 9/21

11:07 am-1:22 pm

1 stop24h 15m

$256

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Wed 10/14

2:17 pm-10:12 am

1 stop21h 55m

Santa Ana J. Wayne/Orange Cnty

Sun 10/18

4:50 pm-1:22 pm

2 stops18h 32m

$263

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Sat 9/26

12:52 pm-9:51 am

1 stop22h 59m

Santa Ana J. Wayne/Orange Cnty

Mon 9/28

2:27 pm-1:32 pm

1 stop21h 05m

$304

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Sat 8/22

11:38 am-6:37 pm

1 stop8h 59m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

6:45 am-6:13 pm

1 stop9h 28m

$315

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/22

11:48 am-5:29 pm

1 stop7h 41m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

1:34 pm-10:27 pm

1 stop6h 53m

$318

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Thu 9/24

1:12 pm-1:32 pm

1 stop26h 20m

Santa Ana J. Wayne/Orange Cnty

Mon 9/28

2:27 pm-1:32 pm

1 stop21h 05m

$318

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Tue 8/18

11:38 am-10:00 pm

2 stops12h 22m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

6:45 am-6:13 pm

1 stop9h 28m

$320

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 8/22

11:48 am-5:29 pm

1 stop7h 41m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

9:45 am-9:21 pm

2 stops9h 36m

$324

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Tue 6/16

6:00 am-12:03 pm

2 stops8h 03m

Santa Ana J. Wayne/Orange Cnty

Tue 6/23

4:00 pm-11:25 pm

1 stop5h 25m

$336
Quickest round-trip

JoplinSanta Ana

JLN - SNA

JLNSNA

Joplin

Thu 8/20

1:53 pm-5:29 pm

1 stop5h 36m

Santa Ana J. Wayne/Orange Cnty

Mon 8/24

4:10 pm-11:44 pm

1 stop5h 34m

$449

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Missouri to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, November is the cheapest month to fly from Missouri to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $88. If you aren’t able to travel during the month of November, then book flights to Santa Ana, California from Missouri during August instead. Flights to Santa Ana, California in August, while not as cheap as those in November, still average around $88.

How far in advance should I book a flight from Missouri to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $458 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from Missouri for as low as $341 on momondo.

Cheap Missouri to Santa Ana, California flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santa Ana, California

Fastest flight time

5h 17m

Direct flights

None
The fastest flight from Missouri to Santa Ana, California takes 5h 17m
There are no direct flights from Missouri to Santa Ana, California. There are no popular flight routes from Missouri to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from Missouri to Santa Ana, California

  • When did momondo last update prices for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents required for your trip to Santa Ana J. Wayne/Orange Cnty Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Ana J. Wayne/Orange Cnty Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santa Ana, California

Compare and see reviews for airlines that fly from Missouri to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $88Free CancellationRating
6.2
8,624 reviews
Search Spirit Airlines flights
DeltaPriceFrom $158Free CancellationRating
7.9
8,453 reviews
Search Delta flights
FrontierPriceFrom $159Free CancellationRating
5.6
2,948 reviews
Search Frontier flights
United AirlinesPriceFrom $227Free CancellationRating
7.4
9,730 reviews
Search United Airlines flights
American AirlinesPriceFrom $235Free CancellationRating
7.1
11,657 reviews
Search American Airlines flights
SouthwestPriceFrom $287Free CancellationRating
8.0
4,292 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santa Ana?

Finding the right flight to Santa Ana from Missouri is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Ana quick and easy, saving you time and money.

Can I find flights from Missouri to Santa Ana with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Ana from Missouri with this policy.

How can momondo help me find flights from Missouri to Santa Ana?

momondo helps you find the best flight between Missouri and Santa Ana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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