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Cheap flights from Missouri to Los Angeles from $72

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Los Angeles departing on 10/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Frontier Logo
8:40 pm - 11:16 amSTL-SNA
16h 36m1 stop
Frontier Logo
3:01 pm - 9:07 amSNA-STL
16h 06m1 stop
$132Frontier
Find Deal
Thu, Oct 30 - Tue, Nov 4
Frontier Logo
6:22 pm - 2:04 pmSTL-SNA
21h 42m2 stops
Frontier Logo
3:01 pm - 9:07 amSNA-STL
16h 06m1 stop
$159Frontier
Find Deal
Thu, Oct 30 - Tue, Nov 4
Spirit Airlines Logo
2:55 pm - 10:03 pmMCI-SNA
9h 08m1 stop
Spirit Airlines Logo
6:45 am - 2:00 pmSNA-MCI
5h 15m1 stop
$189Spirit Airlines
Find Deal
Wed, Oct 15 - Wed, Oct 22
Multiple Airlines Logo
8:28 pm - 1:35 pmMCI-SNA
19h 07m1 stop
Multiple Airlines Logo
5:46 pm - 12:40 amSNA-MCI
28h 54m1 stop
$195Multiple Airlines
Find Deal
Mon, Nov 3 - Tue, Nov 11
Multiple Airlines Logo
8:38 pm - 1:35 pmMCI-SNA
18h 57m1 stop
Multiple Airlines Logo
6:45 am - 5:31 pmSNA-MCI
8h 46m1 stop
$196Multiple Airlines
Find Deal
Mon, Oct 27 - Thu, Oct 30
Spirit Airlines Logo
10:53 am - 10:03 pmMCI-SNA
13h 10m1 stop
Spirit Airlines Logo
6:45 am - 2:00 pmSNA-MCI
5h 15m1 stop
$202Spirit Airlines
Find Deal
Mon, Nov 3 - Tue, Nov 4
American Airlines Logo
2:23 pm - 9:39 pmMCI-SNA
9h 16m1 stop
American Airlines Logo
1:27 pm - 11:07 pmSNA-MCI
7h 40m2 stops
$256American Airlines
Find Deal
Wed, Nov 5 - Sat, Nov 8
Delta Logo
6:15 pm - 10:23 pmMCI-SNA
6h 08m1 stop
Delta Logo
5:20 pm - 12:24 amSNA-MCI
5h 04m1 stop
$261Delta
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Tue, Nov 4 - Mon, Nov 10
Delta Logo
6:15 pm - 10:23 pmMCI-SNA
6h 08m1 stop
Delta Logo
9:32 am - 5:20 pmSNA-MCI
5h 48m1 stop
$265Delta
Find Deal
Mon, Nov 3 - Sat, Nov 8
American Airlines Logo
3:19 pm - 9:39 pmSGF-SNA
8h 20m1 stop
American Airlines Logo
3:03 pm - 10:26 pmSNA-SGF
5h 23m1 stop
$269American Airlines
Find Deal
Wed, Nov 12 - Tue, Nov 18

American Airlines flights from Missouri to Santa Ana

Our best American Airlines deals on Missouri to Santa Ana flight tickets
American Airlines
Nov 5
MCI2:23 pmKansas City
9h 16m
1 stop
SNA9:39 pmSanta Ana J. Wayne/Orange Cnty
Nov 8
SNA1:27 pmSanta Ana J. Wayne/Orange Cnty
7h 40m
2 stops
MCI11:07 pmKansas City
$256
Find similar
American Airlines
Nov 12
SGF3:19 pmSpringfield-Branson
8h 20m
1 stop
SNA9:39 pmSanta Ana J. Wayne/Orange Cnty
Nov 18
SNA3:03 pmSanta Ana J. Wayne/Orange Cnty
5h 23m
1 stop
SGF10:26 pmSpringfield-Branson
$269
Find similar
American Airlines
Nov 19
STL6:00 amLambert-St Louis
8h 43m
1 stop
SNA12:43 pmSanta Ana J. Wayne/Orange Cnty
Dec 3
SNA9:30 amSanta Ana J. Wayne/Orange Cnty
7h 59m
1 stop
STL7:29 pmLambert-St Louis
$335
Find similar

Frontier flights from Missouri to Santa Ana

Our best Frontier deals on Missouri to Santa Ana flight tickets
Frontier
Oct 30
STL8:40 pmLambert-St Louis
16h 36m
1 stop
SNA11:16 amSanta Ana J. Wayne/Orange Cnty
Nov 4
SNA3:01 pmSanta Ana J. Wayne/Orange Cnty
16h 06m
1 stop
STL9:07 amLambert-St Louis
$132
Find similar
Frontier
Oct 30
STL6:22 pmLambert-St Louis
21h 42m
2 stops
SNA2:04 pmSanta Ana J. Wayne/Orange Cnty
Nov 4
SNA3:01 pmSanta Ana J. Wayne/Orange Cnty
16h 06m
1 stop
STL9:07 amLambert-St Louis
$159
Find similar
Frontier
Oct 27
MCI8:38 pmKansas City
18h 57m
1 stop
SNA1:35 pmSanta Ana J. Wayne/Orange Cnty
Oct 29
SNA2:20 pmSanta Ana J. Wayne/Orange Cnty
27h 13m
1 stop
MCI7:33 pmKansas City
$163
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from Missouri to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 10/30

8:40 pm-11:16 am

1 stop16h 36m

Santa Ana J. Wayne/Orange Cnty

Tue 11/4

3:01 pm-9:07 am

1 stop16h 06m

$132

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 10/30

6:22 pm-2:04 pm

2 stops21h 42m

Santa Ana J. Wayne/Orange Cnty

Tue 11/4

3:01 pm-9:07 am

1 stop16h 06m

$159

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Wed 10/15

2:55 pm-10:03 pm

1 stop9h 08m

Santa Ana J. Wayne/Orange Cnty

Wed 10/22

6:45 am-2:00 pm

1 stop5h 15m

$189

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Mon 11/3

8:28 pm-1:35 pm

1 stop19h 07m

Santa Ana J. Wayne/Orange Cnty

Tue 11/11

5:46 pm-12:40 am

1 stop28h 54m

$195

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Mon 10/27

8:38 pm-1:35 pm

1 stop18h 57m

Santa Ana J. Wayne/Orange Cnty

Thu 10/30

6:45 am-5:31 pm

1 stop8h 46m

$196

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Mon 11/3

10:53 am-10:03 pm

1 stop13h 10m

Santa Ana J. Wayne/Orange Cnty

Tue 11/4

6:45 am-2:00 pm

1 stop5h 15m

$202

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Wed 11/5

2:23 pm-9:39 pm

1 stop9h 16m

Santa Ana J. Wayne/Orange Cnty

Sat 11/8

1:27 pm-11:07 pm

2 stops7h 40m

$256

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Tue 11/4

6:15 pm-10:23 pm

1 stop6h 08m

Santa Ana J. Wayne/Orange Cnty

Mon 11/10

5:20 pm-12:24 am

1 stop5h 04m

$261

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Mon 11/3

6:15 pm-10:23 pm

1 stop6h 08m

Santa Ana J. Wayne/Orange Cnty

Sat 11/8

9:32 am-5:20 pm

1 stop5h 48m

$265

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Wed 11/12

3:19 pm-9:39 pm

1 stop8h 20m

Santa Ana J. Wayne/Orange Cnty

Tue 11/18

3:03 pm-10:26 pm

1 stop5h 23m

$269

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Missouri to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana?

The cheapest month to fly to Santa Ana from Missouri is in April. Flight prices, which tend to average around $366, are often lower during this time because this is during the off-season. The month of November is another great option to travel to Santa Ana, with average flight prices from Missouri averaging around $375.

What is the cheapest day to depart on your flight to Santa Ana?

On average, the least expensive day to fly to Santa Ana from Missouri is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $396. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Tuesday is the most expensive day to depart from Missouri because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $475.

What is the cheapest time of day to depart on your flight to Santa Ana?

Our data shows that the cheapest Missouri to Santa Ana flights are usually those with departure times in the evening. Our users have found flights to Santa Ana in the evening for as low as $218. Try not to purchase tickets at noon because they tend to be around $488. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Santa Ana?

You are more likely to see cheaper flights to Santa Ana from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana for around $434 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana from Missouri for as low as $339 on momondo.

Can stopping save me money on Missouri to Santa Ana flights?

You could potentially save up to 49% on your flight if you consider stops on a Missouri to Santa Ana flight.

Cheap Missouri to Santa Ana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santa Ana

Direct flights

None
There are no direct flights from Missouri to Santa Ana. There are no popular flight routes from Missouri to Santa Ana.
Search flight deals

  • When did momondo last update prices for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents required for your trip to Santa Ana J. Wayne/Orange Cnty Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Ana J. Wayne/Orange Cnty Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santa Ana

Compare and see reviews for airlines that fly from Missouri to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $88Free CancellationRating
6.3
8,030 reviews
Search Spirit Airlines flights
FrontierPriceFrom $145Free CancellationRating
5.8
3,171 reviews
Search Frontier flights
DeltaPriceFrom $203Free CancellationRating
7.9
7,964 reviews
Search Delta flights
United AirlinesPriceFrom $264Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
American AirlinesPriceFrom $268Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $331Free CancellationRating
8.0
4,242 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santa Ana?

Finding the right flight to Santa Ana from Missouri is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Ana quick and easy, saving you time and money.

Can I find flights from Missouri to Santa Ana with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Ana from Missouri with this policy.

How can momondo help me find flights from Missouri to Santa Ana?

momondo helps you find the best flight between Missouri and Santa Ana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Santa Ana trip

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