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Cheap flights from Missouri to Los Angeles from $61

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Los Angeles departing on 1/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:00 am - 12:25 pm
MCI
-
SNA
7h 25m1 stop
Multiple Airlines Logo
12:17 pm - 7:51 pm
SNA
-
MCI
5h 34m1 stop
$148Multiple Airlines
Wed, Feb 4 - Fri, Feb 6
Frontier Logo
1:03 pm - 6:46 pm
STL
-
SNA
7h 43m1 stop
Frontier Logo
3:56 pm - 8:50 pm
SNA
-
STL
26h 54m1 stop
$149Frontier
Fri, Jan 30 - Sun, Feb 1
Frontier Logo
3:46 pm - 10:58 am
STL
-
SNA
21h 12m1 stop
Frontier Logo
12:17 pm - 2:46 pm
SNA
-
STL
24h 29m1 stop
$158Frontier
Wed, Jan 21 - Fri, Jan 23
Spirit Airlines Logo
7:00 am - 3:42 pm
MCI
-
SNA
10h 42m1 stop
Spirit Airlines Logo
1:20 pm - 11:33 pm
SNA
-
MCI
8h 13m1 stop
$160Spirit Airlines
Tue, Jan 20 - Tue, Jan 27
Multiple Airlines Logo
3:46 pm - 10:58 am
STL
-
SNA
21h 12m1 stop
Multiple Airlines Logo
6:45 am - 8:50 pm
SNA
-
STL
12h 05m1 stop
$161Multiple Airlines
Wed, Jan 21 - Mon, Jan 26
Spirit Airlines Logo
7:00 am - 3:42 pm
MCI
-
SNA
10h 42m1 stop
Spirit Airlines Logo
1:20 pm - 11:33 pm
SNA
-
MCI
8h 13m1 stop
$172Spirit Airlines
Tue, Jan 20 - Tue, Feb 3
American Airlines Logo
4:29 pm - 8:55 pm
SGF
-
SNA
6h 26m1 stop
American Airlines Logo
3:15 pm - 10:47 pm
SNA
-
SGF
5h 32m1 stop
$269American Airlines
Wed, Jan 7 - Wed, Jan 14
American Airlines Logo
5:53 am - 9:32 am
SGF
-
SNA
5h 39m1 stop
American Airlines Logo
3:21 pm - 11:46 pm
SNA
-
SGF
6h 25m1 stop
$294American Airlines
Fri, Apr 24 - Wed, May 6
United Airlines Logo
6:15 am - 2:07 pm
SGF
-
SNA
9h 52m1 stop
United Airlines Logo
7:00 am - 4:22 pm
SNA
-
SGF
7h 22m1 stop
$335United Airlines
Fri, Jan 23 - Mon, Jan 26
United Airlines Logo
11:17 am - 6:41 pm
COU
-
SNA
9h 24m1 stop
United Airlines Logo
1:17 pm - 8:33 pm
SNA
-
COU
5h 16m1 stop
$338United Airlines
Sat, Jan 10 - Tue, Jan 13

Spirit Airlines flights from Missouri to Santa Ana, California

Our best Spirit Airlines deals on Missouri to Santa Ana, California flight tickets
Spirit Airlines
Jan 20
MCI7:00 amKansas City
10h 42m
1 stop
SNA3:42 pmSanta Ana J. Wayne/Orange Cnty
Jan 21
SNA1:20 pmSanta Ana J. Wayne/Orange Cnty
8h 13m
1 stop
MCI11:33 pmKansas City
$133
Find similar
Spirit Airlines
Jan 20
MCI7:00 amKansas City
7h 25m
1 stop
SNA12:25 pmSanta Ana J. Wayne/Orange Cnty
Jan 22
SNA1:20 pmSanta Ana J. Wayne/Orange Cnty
8h 13m
1 stop
MCI11:33 pmKansas City
$145
Find similar
Spirit Airlines
Jan 9
MCI7:00 amKansas City
7h 25m
1 stop
SNA12:25 pmSanta Ana J. Wayne/Orange Cnty
Jan 13
SNA4:37 pmSanta Ana J. Wayne/Orange Cnty
4h 56m
1 stop
MCI11:33 pmKansas City
$173
Find similar

Delta flights from Missouri to Santa Ana, California

Our best Delta deals on Missouri to Santa Ana, California flight tickets
Delta
Jan 6
STL11:23 amLambert-St Louis
12h 55m
2 stops
SNA10:18 pmSanta Ana J. Wayne/Orange Cnty
Jan 10
SNA7:30 amSanta Ana J. Wayne/Orange Cnty
12h 05m
2 stops
STL9:35 pmLambert-St Louis
$256
Find similar
Delta
Jan 6
STL11:23 amLambert-St Louis
12h 55m
2 stops
SNA10:18 pmSanta Ana J. Wayne/Orange Cnty
Jan 13
SNA7:30 amSanta Ana J. Wayne/Orange Cnty
12h 05m
2 stops
STL9:35 pmLambert-St Louis
$288
Find similar
Delta
Jan 6
STL12:00 pmLambert-St Louis
10h 04m
1 stop
SNA8:04 pmSanta Ana J. Wayne/Orange Cnty
Jan 10
SNA7:30 amSanta Ana J. Wayne/Orange Cnty
12h 05m
2 stops
STL9:35 pmLambert-St Louis
$314
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Missouri to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Wed 2/4

7:00 am-12:25 pm

1 stop7h 25m

Santa Ana J. Wayne/Orange Cnty

Fri 2/6

12:17 pm-7:51 pm

1 stop5h 34m

$148

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 1/30

1:03 pm-6:46 pm

1 stop7h 43m

Santa Ana J. Wayne/Orange Cnty

Sun 2/1

3:56 pm-8:50 pm

1 stop26h 54m

$149

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 1/21

3:46 pm-10:58 am

1 stop21h 12m

Santa Ana J. Wayne/Orange Cnty

Fri 1/23

12:17 pm-2:46 pm

1 stop24h 29m

$158

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Tue 1/20

7:00 am-3:42 pm

1 stop10h 42m

Santa Ana J. Wayne/Orange Cnty

Tue 1/27

1:20 pm-11:33 pm

1 stop8h 13m

$160

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 1/21

3:46 pm-10:58 am

1 stop21h 12m

Santa Ana J. Wayne/Orange Cnty

Mon 1/26

6:45 am-8:50 pm

1 stop12h 05m

$161

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Tue 1/20

7:00 am-3:42 pm

1 stop10h 42m

Santa Ana J. Wayne/Orange Cnty

Tue 2/3

1:20 pm-11:33 pm

1 stop8h 13m

$172

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Wed 1/7

4:29 pm-8:55 pm

1 stop6h 26m

Santa Ana J. Wayne/Orange Cnty

Wed 1/14

3:15 pm-10:47 pm

1 stop5h 32m

$269

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Fri 4/24

5:53 am-9:32 am

1 stop5h 39m

Santa Ana J. Wayne/Orange Cnty

Wed 5/6

3:21 pm-11:46 pm

1 stop6h 25m

$294

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Fri 1/23

6:15 am-2:07 pm

1 stop9h 52m

Santa Ana J. Wayne/Orange Cnty

Mon 1/26

7:00 am-4:22 pm

1 stop7h 22m

$335

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Sat 1/10

11:17 am-6:41 pm

1 stop9h 24m

Santa Ana J. Wayne/Orange Cnty

Tue 1/13

1:17 pm-8:33 pm

1 stop5h 16m

$338

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Missouri to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, November is the cheapest month to fly from Missouri to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $345. If you aren’t able to travel during the month of November, then book flights to Santa Ana, California from Missouri during April instead. Flights to Santa Ana, California in April, while not as cheap as those in November, still average around $366.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Missouri to Santa Ana, California is on a Wednesday. Travelers who choose to depart for Santa Ana, California on a Wednesday will often find tickets for as low as $396. The most expensive day to fly to Santa Ana, California is Tuesday, with ticket prices averaging around $475.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the evening is the cheapest time of day to fly from Missouri to Santa Ana, California when you can find flight prices for as low as $218. Flying to Santa Ana, California in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is at noon when prices are around $488.

How far in advance should I book a flight to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $435 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from Missouri for as low as $302 on momondo.

Can stopping save me money on Missouri to Santa Ana, California flights?

You could potentially save up to 75% on your flight if you consider stops on a Missouri to Santa Ana, California flight.

Cheap Missouri to Santa Ana, California flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santa Ana, California

Fastest flight time

5h 16m

Direct flights

None
The fastest flight from Missouri to Santa Ana, California takes 5h 16m
There are no direct flights from Missouri to Santa Ana, California. There are no popular flight routes from Missouri to Santa Ana, California.
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  • When did momondo last update prices for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents required for your trip to Santa Ana J. Wayne/Orange Cnty Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Ana J. Wayne/Orange Cnty Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santa Ana, California

Compare and see reviews for airlines that fly from Missouri to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $88Free CancellationRating
6.3
8,180 reviews
Search Spirit Airlines flights
FrontierPriceFrom $126Free CancellationRating
5.8
3,084 reviews
Search Frontier flights
DeltaPriceFrom $203Free CancellationRating
7.9
8,007 reviews
Search Delta flights
United AirlinesPriceFrom $264Free CancellationRating
7.4
9,094 reviews
Search United Airlines flights
American AirlinesPriceFrom $268Free CancellationRating
7.2
11,049 reviews
Search American Airlines flights
SouthwestPriceFrom $310Free CancellationRating
7.9
4,253 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santa Ana?

Finding the right flight to Santa Ana from Missouri is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Ana quick and easy, saving you time and money.

Can I find flights from Missouri to Santa Ana with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Ana from Missouri with this policy.

How can momondo help me find flights from Missouri to Santa Ana?

momondo helps you find the best flight between Missouri and Santa Ana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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