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Cheap flights from Missouri to Los Angeles from $89

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Los Angeles departing on 8/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:45 pm - 2:48 pm
STL
-
SNA
22h 03m
1 stop
Frontier Logo
7:53 pm - 5:50 pm
SNA
-
STL
19h 57m
1 stop
$187Frontier
Fri, Aug 21 - Mon, Aug 24
Multiple Airlines Logo
6:45 pm - 2:48 pm
STL
-
SNA
22h 03m
1 stop
Multiple Airlines Logo
7:30 am - 5:50 pm
SNA
-
STL
8h 20m
1 stop
$194Multiple Airlines
Fri, Aug 21 - Tue, Aug 25
Frontier Logo
6:45 pm - 12:31 pm
STL
-
SNA
19h 46m
1 stop
Frontier Logo
7:53 pm - 5:50 pm
SNA
-
STL
19h 57m
1 stop
$197Frontier
Wed, Aug 19 - Mon, Aug 24
Multiple Airlines Logo
8:00 am - 3:01 pm
STL
-
SNA
9h 01m
1 stop
Multiple Airlines Logo
7:53 pm - 5:50 pm
SNA
-
STL
19h 57m
1 stop
$205Multiple Airlines
Tue, Aug 18 - Mon, Aug 24
Allegiant Air Logo
11:56 am - 10:43 am
SGF
-
SNA
24h 47m
1 stop
Allegiant Air Logo
6:03 pm - 8:05 pm
SNA
-
SGF
24h 02m
1 stop
$308Allegiant Air
Wed, Jul 29 - Sun, Aug 2
American Airlines Logo
12:43 pm - 8:39 pm
COU
-
SNA
9h 56m
1 stop
American Airlines Logo
7:45 am - 6:03 pm
SNA
-
COU
8h 18m
1 stop
$318American Airlines
Wed, Aug 19 - Wed, Aug 26
United Airlines Logo
10:55 am - 6:51 pm
COU
-
SNA
9h 56m
1 stop
United Airlines Logo
11:10 am - 10:55 pm
SNA
-
COU
9h 45m
2 stops
$324United Airlines
Wed, Aug 19 - Wed, Aug 26
American Airlines Logo
6:00 am - 9:42 am
SGF
-
SNA
5h 42m
1 stop
American Airlines Logo
4:31 pm - 11:55 pm
SNA
-
SGF
5h 24m
1 stop
$329American Airlines
Fri, Aug 14 - Sun, Aug 23
United Airlines Logo
6:15 am - 1:53 pm
COU
-
SNA
9h 38m
2 stops
United Airlines Logo
11:10 am - 10:55 pm
SNA
-
COU
9h 45m
2 stops
$329United Airlines
Wed, Aug 19 - Wed, Aug 26
Allegiant Air Logo
1:31 pm - 8:53 am
SGF
-
SNA
21h 22m
2 stops
Allegiant Air Logo
6:03 pm - 8:09 pm
SNA
-
SGF
24h 06m
1 stop
$374Allegiant Air
Thu, Jul 30 - Thu, Aug 6

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American Airlines flights from Missouri to Santa Ana, California

Our best American Airlines deals on Missouri to Santa Ana, California flight tickets
American Airlines
Aug 19
COU12:43 pmColumbia Regional
9h 56m
1 stop
SNA8:39 pmSanta Ana J. Wayne/Orange Cnty
Aug 26
SNA7:45 amSanta Ana J. Wayne/Orange Cnty
8h 18m
1 stop
COU6:03 pmColumbia Regional
$318
American Airlines
Aug 14
SGF6:00 amSpringfield-Branson
5h 42m
1 stop
SNA9:42 amSanta Ana J. Wayne/Orange Cnty
Aug 23
SNA4:31 pmSanta Ana J. Wayne/Orange Cnty
5h 24m
1 stop
SGF11:55 pmSpringfield-Branson
$329
American Airlines
Aug 13
COU7:00 amColumbia Regional
8h 30m
1 stop
SNA1:30 pmSanta Ana J. Wayne/Orange Cnty
Aug 19
SNA2:29 pmSanta Ana J. Wayne/Orange Cnty
5h 59m
1 stop
COU10:28 pmColumbia Regional
$379

United Airlines flights from Missouri to Santa Ana, California

Our best United Airlines deals on Missouri to Santa Ana, California flight tickets
United Airlines
Aug 19
COU10:55 amColumbia Regional
9h 56m
1 stop
SNA6:51 pmSanta Ana J. Wayne/Orange Cnty
Aug 26
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
9h 45m
2 stops
COU10:55 pmColumbia Regional
$324
United Airlines
Aug 19
COU6:15 amColumbia Regional
9h 38m
2 stops
SNA1:53 pmSanta Ana J. Wayne/Orange Cnty
Aug 26
SNA11:10 amSanta Ana J. Wayne/Orange Cnty
9h 45m
2 stops
COU10:55 pmColumbia Regional
$329
United Airlines
Aug 15
COU9:00 amColumbia Regional
8h 20m
1 stop
SNA3:20 pmSanta Ana J. Wayne/Orange Cnty
Aug 22
SNA2:10 pmSanta Ana J. Wayne/Orange Cnty
6h 45m
1 stop
COU10:55 pmColumbia Regional
$408

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 2, 2026.
Use the filters below to find and compare flights from Missouri to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 8/21

6:45 pm-2:48 pm

1 stop22h 03m

Santa Ana J. Wayne/Orange Cnty

Mon 8/24

7:53 pm-5:50 pm

1 stop19h 57m

$187

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 8/21

6:45 pm-2:48 pm

1 stop22h 03m

Santa Ana J. Wayne/Orange Cnty

Tue 8/25

7:30 am-5:50 pm

1 stop8h 20m

$194

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Wed 8/19

6:45 pm-12:31 pm

1 stop19h 46m

Santa Ana J. Wayne/Orange Cnty

Mon 8/24

7:53 pm-5:50 pm

1 stop19h 57m

$197

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Tue 8/18

8:00 am-3:01 pm

1 stop9h 01m

Santa Ana J. Wayne/Orange Cnty

Mon 8/24

7:53 pm-5:50 pm

1 stop19h 57m

$205

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Wed 7/29

11:56 am-10:43 am

1 stop24h 47m

Santa Ana J. Wayne/Orange Cnty

Sun 8/2

6:03 pm-8:05 pm

1 stop24h 02m

$308

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 8/19

12:43 pm-8:39 pm

1 stop9h 56m

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

7:45 am-6:03 pm

1 stop8h 18m

$318

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 8/19

10:55 am-6:51 pm

1 stop9h 56m

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

11:10 am-10:55 pm

2 stops9h 45m

$324
Quickest round-trip

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Fri 8/14

6:00 am-9:42 am

1 stop5h 42m

Santa Ana J. Wayne/Orange Cnty

Sun 8/23

4:31 pm-11:55 pm

1 stop5h 24m

$329

ColumbiaSanta Ana

COU - SNA

COUSNA

Columbia Regional

Wed 8/19

6:15 am-1:53 pm

2 stops9h 38m

Santa Ana J. Wayne/Orange Cnty

Wed 8/26

11:10 am-10:55 pm

2 stops9h 45m

$329

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Thu 7/30

1:31 pm-8:53 am

2 stops21h 22m

Santa Ana J. Wayne/Orange Cnty

Thu 8/6

6:03 pm-8:09 pm

1 stop24h 06m

$374

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Missouri to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, November is the cheapest month to fly from Missouri to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $88. If you aren’t able to travel during the month of November, then book flights to Santa Ana, California from Missouri during August instead. Flights to Santa Ana, California in August, while not as cheap as those in November, still average around $88.

How far in advance should I book a flight from Missouri to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $464 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from Missouri for as low as $300 on momondo.

Cheap Missouri to Santa Ana, California flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santa Ana, California

Fastest flight time

5h 07m

Direct flights

None
The fastest flight from Missouri to Santa Ana, California takes 5h 07m
There are no direct flights from Missouri to Santa Ana, California. There are no popular flight routes from Missouri to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from Missouri to Santa Ana, California

  • When did momondo last update prices for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents required for your trip to Santa Ana J. Wayne/Orange Cnty Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Ana J. Wayne/Orange Cnty Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santa Ana, California

Compare and see reviews for airlines that fly from Missouri to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $158Free CancellationRating
7.8
8,452 reviews
Search Delta flights
FrontierPriceFrom $159Free CancellationRating
5.6
2,850 reviews
Search Frontier flights
United AirlinesPriceFrom $227Free CancellationRating
7.4
9,926 reviews
Search United Airlines flights
American AirlinesPriceFrom $255Free CancellationRating
7.1
11,769 reviews
Search American Airlines flights
SouthwestPriceFrom $303Free CancellationRating
7.9
4,249 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santa Ana?

Finding the right flight to Santa Ana from Missouri is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Ana quick and easy, saving you time and money.

Can I find flights from Missouri to Santa Ana with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Ana from Missouri with this policy.

How can momondo help me find flights from Missouri to Santa Ana?

momondo helps you find the best flight between Missouri and Santa Ana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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