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Cheap flights from Missouri to Los Angeles from $48

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Los Angeles departing on 12/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Spirit Airlines Logo
6:30 am - 10:44 amMCI-SNA
6h 14m1 stop
Spirit Airlines Logo
6:45 am - 2:52 pmSNA-MCI
6h 07m1 stop
$118Spirit Airlines
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Tue, Dec 9 - Thu, Dec 11
Frontier Logo
1:16 pm - 5:39 pmSTL-SNA
6h 23m1 stop
Frontier Logo
8:18 pm - 12:15 pmSNA-STL
13h 57m1 stop
$130Frontier
Find Deal
Mon, Dec 8 - Thu, Jan 15
Multiple Airlines Logo
7:43 pm - 12:22 pmSTL-SNA
18h 39m1 stop
Multiple Airlines Logo
4:37 pm - 8:53 pmSNA-STL
26h 16m1 stop
$148Multiple Airlines
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Fri, Jan 9 - Wed, Jan 14
Multiple Airlines Logo
7:00 am - 12:25 pmMCI-SNA
7h 25m1 stop
Multiple Airlines Logo
10:38 am - 8:09 pmSNA-MCI
7h 31m1 stop
$156Multiple Airlines
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Tue, Feb 3 - Thu, Feb 26
American Airlines Logo
7:30 am - 12:14 pmSGF-SNA
6h 44m1 stop
American Airlines Logo
3:21 pm - 11:46 pmSNA-SGF
6h 25m1 stop
$269American Airlines
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Tue, Apr 28 - Wed, May 6
Delta Logo
7:00 am - 4:14 pmSTL-SNA
11h 14m2 stops
Delta Logo
7:30 am - 9:35 pmSNA-STL
12h 05m2 stops
$276Delta
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Fri, Jan 9 - Wed, Jan 14
United Airlines Logo
2:55 pm - 9:49 pmSGF-SNA
8h 54m1 stop
United Airlines Logo
10:40 am - 10:13 pmSNA-SGF
9h 33m1 stop
$288United Airlines
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Tue, Dec 2 - Tue, Dec 9
United Airlines Logo
8:50 am - 8:19 pmSGF-SNA
13h 29m2 stops
United Airlines Logo
10:25 am - 5:53 pmSNA-SGF
5h 28m1 stop
$291United Airlines
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Tue, Apr 28 - Wed, May 6
Delta Logo
2:20 pm - 10:21 pmSTL-SNA
10h 01m2 stops
Delta Logo
7:15 am - 7:10 pmSNA-STL
9h 55m2 stops
$297Delta
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Thu, Dec 4 - Thu, Dec 11
American Airlines Logo
7:12 am - 2:22 pmSGF-SNA
9h 10m1 stop
American Airlines Logo
7:45 am - 5:04 pmSNA-SGF
7h 19m1 stop
$346American Airlines
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Mon, Mar 2 - Sat, Mar 7

United Airlines flights from Missouri to Santa Ana, California

Our best United Airlines deals on Missouri to Santa Ana, California flight tickets
United Airlines
Dec 2
SGF2:55 pmSpringfield-Branson
8h 54m
1 stop
SNA9:49 pmSanta Ana J. Wayne/Orange Cnty
Dec 9
SNA10:40 amSanta Ana J. Wayne/Orange Cnty
9h 33m
1 stop
SGF10:13 pmSpringfield-Branson
$288
Find similar
United Airlines
Apr 28
SGF8:50 amSpringfield-Branson
13h 29m
2 stops
SNA8:19 pmSanta Ana J. Wayne/Orange Cnty
May 6
SNA10:25 amSanta Ana J. Wayne/Orange Cnty
5h 28m
1 stop
SGF5:53 pmSpringfield-Branson
$291
Find similar
United Airlines
Nov 11
COU8:00 amColumbia Regional
8h 58m
2 stops
SNA2:58 pmSanta Ana J. Wayne/Orange Cnty
Dec 13
SNA10:40 amSanta Ana J. Wayne/Orange Cnty
8h 42m
1 stop
COU9:22 pmColumbia Regional
$334
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Frontier flights from Missouri to Santa Ana, California

Our best Frontier deals on Missouri to Santa Ana, California flight tickets
Frontier
Dec 8
STL1:16 pmLambert-St Louis
6h 23m
1 stop
SNA5:39 pmSanta Ana J. Wayne/Orange Cnty
Jan 15
SNA8:18 pmSanta Ana J. Wayne/Orange Cnty
13h 57m
1 stop
STL12:15 pmLambert-St Louis
$130
Find similar
Frontier
Dec 3
STL7:43 pmLambert-St Louis
18h 59m
1 stop
SNA12:42 pmSanta Ana J. Wayne/Orange Cnty
Dec 7
SNA6:34 pmSanta Ana J. Wayne/Orange Cnty
15h 38m
1 stop
STL12:12 pmLambert-St Louis
$134
Find similar
Frontier
Nov 18
STL7:45 pmLambert-St Louis
19h 45m
1 stop
SNA1:30 pmSanta Ana J. Wayne/Orange Cnty
Nov 21
SNA12:04 pmSanta Ana J. Wayne/Orange Cnty
19h 58m
1 stop
STL10:02 amLambert-St Louis
$137
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momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Missouri to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Tue 12/9

6:30 am-10:44 am

1 stop6h 14m

Santa Ana J. Wayne/Orange Cnty

Thu 12/11

6:45 am-2:52 pm

1 stop6h 07m

$118

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Mon 12/8

1:16 pm-5:39 pm

1 stop6h 23m

Santa Ana J. Wayne/Orange Cnty

Thu 1/15

8:18 pm-12:15 pm

1 stop13h 57m

$130

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 1/9

7:43 pm-12:22 pm

1 stop18h 39m

Santa Ana J. Wayne/Orange Cnty

Wed 1/14

4:37 pm-8:53 pm

1 stop26h 16m

$148

Kansas CitySanta Ana

MCI - SNA

MCISNA

Kansas City

Tue 2/3

7:00 am-12:25 pm

1 stop7h 25m

Santa Ana J. Wayne/Orange Cnty

Thu 2/26

10:38 am-8:09 pm

1 stop7h 31m

$156

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Tue 4/28

7:30 am-12:14 pm

1 stop6h 44m

Santa Ana J. Wayne/Orange Cnty

Wed 5/6

3:21 pm-11:46 pm

1 stop6h 25m

$269

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Fri 1/9

7:00 am-4:14 pm

2 stops11h 14m

Santa Ana J. Wayne/Orange Cnty

Wed 1/14

7:30 am-9:35 pm

2 stops12h 05m

$276

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Tue 12/2

2:55 pm-9:49 pm

1 stop8h 54m

Santa Ana J. Wayne/Orange Cnty

Tue 12/9

10:40 am-10:13 pm

1 stop9h 33m

$288

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Tue 4/28

8:50 am-8:19 pm

2 stops13h 29m

Santa Ana J. Wayne/Orange Cnty

Wed 5/6

10:25 am-5:53 pm

1 stop5h 28m

$291

St. LouisSanta Ana

STL - SNA

STLSNA

Lambert-St Louis

Thu 12/4

2:20 pm-10:21 pm

2 stops10h 01m

Santa Ana J. Wayne/Orange Cnty

Thu 12/11

7:15 am-7:10 pm

2 stops9h 55m

$297

SpringfieldSanta Ana

SGF - SNA

SGFSNA

Springfield-Branson

Mon 3/2

7:12 am-2:22 pm

1 stop9h 10m

Santa Ana J. Wayne/Orange Cnty

Sat 3/7

7:45 am-5:04 pm

1 stop7h 19m

$346

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Missouri to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Ana, California?

In general, April is the cheapest month to fly from Missouri to Santa Ana, California. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $366. If you aren’t able to travel during the month of April, then book flights to Santa Ana, California from Missouri during November instead. Flights to Santa Ana, California in November, while not as cheap as those in April, still average around $382.

What is the cheapest day to depart on your flight to Santa Ana, California?

The cheapest day to depart from Missouri to Santa Ana, California is on a Wednesday. Travelers who choose to depart for Santa Ana, California on a Wednesday will often find tickets for as low as $396. The most expensive day to fly to Santa Ana, California is Tuesday, with ticket prices averaging around $475.

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the evening is the cheapest time of day to fly from Missouri to Santa Ana, California when you can find flight prices for as low as $218. Flying to Santa Ana, California in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is at noon when prices are around $488.

How far in advance should I book a flight to Santa Ana, California?

You are more likely to see cheaper flights to Santa Ana, California from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Santa Ana, California for around $433 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santa Ana, California from Missouri for as low as $306 on momondo.

Can stopping save me money on Missouri to Santa Ana, California flights?

You could potentially save up to 61% on your flight if you consider stops on a Missouri to Santa Ana, California flight.

Cheap Missouri to Santa Ana, California flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Santa Ana, California

Direct flights

None
There are no direct flights from Missouri to Santa Ana, California. There are no popular flight routes from Missouri to Santa Ana, California.
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  • When did momondo last update prices for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport are updated daily.

  • How many operators does momondo search for flights from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Missouri to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents required for your trip to Santa Ana J. Wayne/Orange Cnty Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Ana J. Wayne/Orange Cnty Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Missouri to Santa Ana, California

Compare and see reviews for airlines that fly from Missouri to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $88Free CancellationRating
6.3
8,122 reviews
Search Spirit Airlines flights
FrontierPriceFrom $145Free CancellationRating
5.8
3,116 reviews
Search Frontier flights
DeltaPriceFrom $203Free CancellationRating
7.9
8,001 reviews
Search Delta flights
United AirlinesPriceFrom $264Free CancellationRating
7.4
9,007 reviews
Search United Airlines flights
American AirlinesPriceFrom $268Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
SouthwestPriceFrom $303Free CancellationRating
8.0
4,241 reviews
Search Southwest flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Santa Ana?

Finding the right flight to Santa Ana from Missouri is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santa Ana quick and easy, saving you time and money.

Can I find flights from Missouri to Santa Ana with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santa Ana from Missouri with this policy.

How can momondo help me find flights from Missouri to Santa Ana?

momondo helps you find the best flight between Missouri and Santa Ana by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Santa Ana right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Santa Ana flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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