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Cheap flights from La Crosse to San Francisco from $484

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from La Crosse to San Francisco departing on 4/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from La Crosse to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:13 am - 10:58 am
LSE
-
SFO
6h 45m1 stop
American Airlines Logo
11:47 pm - 10:56 am
SFO
-
LSE
9h 09m1 stop
$484American Airlines
Tue, Apr 7 - Mon, Apr 27
American Airlines Logo
10:03 am - 7:14 pm
LSE
-
SFO
11h 11m2 stops
American Airlines Logo
11:23 pm - 9:32 am
SFO
-
LSE
8h 09m1 stop
$490American Airlines
Wed, Feb 25 - Sun, Mar 1
American Airlines Logo
10:03 am - 7:14 pm
LSE
-
SFO
11h 11m2 stops
American Airlines Logo
6:34 pm - 9:32 am
SFO
-
LSE
12h 58m2 stops
$495American Airlines
Wed, Feb 25 - Sun, Mar 1
American Airlines Logo
6:28 pm - 11:45 pm
LSE
-
SFO
7h 17m1 stop
American Airlines Logo
11:47 pm - 9:24 am
SFO
-
LSE
7h 37m1 stop
$514American Airlines
Fri, Mar 13 - Mon, Mar 16
American Airlines Logo
6:28 pm - 11:45 pm
LSE
-
SFO
7h 17m1 stop
American Airlines Logo
7:00 pm - 9:24 am
SFO
-
LSE
12h 24m2 stops
$520American Airlines
Fri, Mar 13 - Mon, Mar 16
American Airlines Logo
10:38 am - 8:56 pm
LSE
-
SFO
12h 18m2 stops
American Airlines Logo
7:00 pm - 9:24 am
SFO
-
LSE
12h 24m2 stops
$525American Airlines
Fri, Mar 13 - Mon, Mar 16
American Airlines Logo
5:08 pm - 10:34 pm
LSE
-
SFO
7h 26m1 stop
American Airlines Logo
6:00 am - 4:16 pm
SFO
-
LSE
8h 16m1 stop
$526American Airlines
Sat, Jan 10 - Wed, Jan 14
American Airlines Logo
5:08 pm - 10:34 pm
LSE
-
SFO
7h 26m1 stop
American Airlines Logo
6:00 am - 4:16 pm
SFO
-
LSE
8h 16m2 stops
$532American Airlines
Sat, Jan 10 - Wed, Jan 14
American Airlines Logo
6:00 am - 4:01 pm
LSE
-
SFO
12h 01m2 stops
American Airlines Logo
12:41 pm - 10:16 pm
SFO
-
LSE
7h 35m1 stop
$550American Airlines
Tue, Jan 27 - Wed, Feb 11
American Airlines Logo
6:00 am - 5:24 pm
LSE
-
SFO
13h 24m2 stops
American Airlines Logo
7:00 am - 10:17 pm
SFO
-
LSE
13h 17m2 stops
$555American Airlines
Tue, Jan 27 - Sat, Feb 14

American Airlines flights from La Crosse to San Francisco

Our best American Airlines deals on La Crosse to San Francisco flight tickets
American Airlines
Apr 7
LSE6:13 amLa Crosse
6h 45m
1 stop
SFO10:58 amSan Francisco
Apr 27
SFO11:47 pmSan Francisco
9h 09m
1 stop
LSE10:56 amLa Crosse
$484
Find similar
American Airlines
Feb 25
LSE10:03 amLa Crosse
11h 11m
2 stops
SFO7:14 pmSan Francisco
Mar 1
SFO11:23 pmSan Francisco
8h 09m
1 stop
LSE9:32 amLa Crosse
$490
Find similar
American Airlines
Feb 25
LSE10:03 amLa Crosse
11h 11m
2 stops
SFO7:14 pmSan Francisco
Mar 1
SFO6:34 pmSan Francisco
12h 58m
2 stops
LSE9:32 amLa Crosse
$495
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from La Crosse to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from La Crosse to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Tue 4/7

6:13 am-10:58 am

1 stop6h 45m

San Francisco

Mon 4/27

11:47 pm-10:56 am

1 stop9h 09m

$484

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Wed 2/25

10:03 am-7:14 pm

2 stops11h 11m

San Francisco

Sun 3/1

11:23 pm-9:32 am

1 stop8h 09m

$490

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Wed 2/25

10:03 am-7:14 pm

2 stops11h 11m

San Francisco

Sun 3/1

6:34 pm-9:32 am

2 stops12h 58m

$495

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Fri 3/13

6:28 pm-11:45 pm

1 stop7h 17m

San Francisco

Mon 3/16

11:47 pm-9:24 am

1 stop7h 37m

$514

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Fri 3/13

6:28 pm-11:45 pm

1 stop7h 17m

San Francisco

Mon 3/16

7:00 pm-9:24 am

2 stops12h 24m

$520

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Fri 3/13

10:38 am-8:56 pm

2 stops12h 18m

San Francisco

Mon 3/16

7:00 pm-9:24 am

2 stops12h 24m

$525

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Sat 1/10

5:08 pm-10:34 pm

1 stop7h 26m

San Francisco

Wed 1/14

6:00 am-4:16 pm

1 stop8h 16m

$526

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Sat 1/10

5:08 pm-10:34 pm

1 stop7h 26m

San Francisco

Wed 1/14

6:00 am-4:16 pm

2 stops8h 16m

$532

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Tue 1/27

6:00 am-4:01 pm

2 stops12h 01m

San Francisco

Wed 2/11

12:41 pm-10:16 pm

1 stop7h 35m

$550

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Tue 1/27

6:00 am-5:24 pm

2 stops13h 24m

San Francisco

Sat 2/14

7:00 am-10:17 pm

2 stops13h 17m

$555

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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How to get the cheapest flight ticket from La Crosse to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from La Crosse to San Francisco is on a Saturday when prices can be found for as low as $474. The most expensive day to fly to San Francisco is Wednesday, with ticket prices averaging around $619.

When to book flights from La Crosse to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from La Crosse to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap La Crosse to San Francisco (LSE to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from La Crosse to San Francisco

Fastest flight time

6h 45m

Direct flights

None
The fastest flight from La Crosse to San Francisco takes 6h 45m
There are no direct flights from La Crosse to San Francisco. There are no popular flight routes from La Crosse to San Francisco.
Search flight deals

  • How far is La Crosse to San Francisco by plane?

    There are 1670.6 mi between La Crosse and San Francisco. 6h 45m is a normal flight duration for this route.

  • When did momondo last update prices for flights from La Crosse Airport to San Francisco Airport?

    Prices for flights from La Crosse Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from La Crosse Airport to San Francisco Airport?

  • How old do you have to be to fly from La Crosse Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from La Crosse Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents you'll need for your trip to San Francisco Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from La Crosse to San Francisco?

Best airlines flying from La Crosse to San Francisco

Compare and see reviews for airlines that fly from La Crosse to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $454Free CancellationRating
7.2
11,072 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Hayward
Calistoga
Big Sur
Santa Clara
Walnut Creek
Berkeley
Daly City
Fremont
Half Moon Bay
Vallejo
Livermore
Salinas
Sunnyvale
Pacifica

Why use momondo?

Why should I use momondo to find a flight deal from La Crosse to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from La Crosse to San Francisco for you.

Can I find flights from La Crosse to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from La Crosse which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from La Crosse to San Francisco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from La Crosse to San Francisco.

I’m not ready to book a flight from La Crosse to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from La Crosse are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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