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Cheap flights from La Crosse to San Francisco from $457

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from La Crosse to San Francisco departing on 9/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from La Crosse to San Francisco (LSE-SFO)

Cheap round-trip flights

American Airlines Logo
6:00 am - 12:31 pmLSE-SFO
8h 31m1 stop
American Airlines Logo
12:47 am - 9:19 amSFO-LSE
6h 32m1 stop
$457American Airlines
Find Deal
Wed, Sep 17 - Tue, Sep 23
American Airlines Logo
6:21 pm - 11:09 pmLSE-SFO
6h 48m1 stop
American Airlines Logo
11:17 am - 10:04 pmSFO-LSE
8h 47m2 stops
$462American Airlines
Find Deal
Wed, Sep 17 - Wed, Sep 24
American Airlines Logo
6:00 am - 3:09 pmLSE-SFO
11h 09m2 stops
American Airlines Logo
6:45 am - 10:04 pmSFO-LSE
13h 19m2 stops
$468American Airlines
Find Deal
Wed, Sep 17 - Wed, Sep 24
American Airlines Logo
6:21 pm - 11:09 pmLSE-SFO
6h 48m1 stop
American Airlines Logo
6:10 am - 5:45 pmSFO-LSE
9h 35m1 stop
$484American Airlines
Find Deal
Wed, Oct 1 - Mon, Oct 6
American Airlines Logo
6:00 am - 3:09 pmLSE-SFO
11h 09m2 stops
American Airlines Logo
2:10 pm - 11:26 pmSFO-LSE
7h 16m1 stop
$490American Airlines
Find Deal
Wed, Oct 1 - Mon, Oct 6
American Airlines Logo
9:50 am - 7:02 pmLSE-SFO
11h 12m2 stops
American Airlines Logo
9:16 am - 11:26 pmSFO-LSE
12h 10m2 stops
$495American Airlines
Find Deal
Wed, Oct 1 - Mon, Oct 6
American Airlines Logo
5:58 am - 10:58 amLSE-SFO
7h 00m1 stop
American Airlines Logo
1:34 pm - 9:45 pmSFO-LSE
6h 11m1 stop
$574American Airlines
Find Deal
Thu, Dec 11 - Sat, Dec 13
American Airlines Logo
2:48 pm - 9:57 pmLSE-SFO
9h 09m2 stops
American Airlines Logo
1:34 pm - 9:45 pmSFO-LSE
6h 11m1 stop
$580American Airlines
Find Deal
Thu, Dec 11 - Sat, Dec 13
American Airlines Logo
5:58 am - 3:44 pmLSE-SFO
11h 46m2 stops
American Airlines Logo
12:27 am - 2:21 pmSFO-LSE
11h 54m2 stops
$585American Airlines
Find Deal
Thu, Dec 11 - Fri, Dec 12
American Airlines Logo
6:32 pm - 9:18 amLSE-SFO
16h 46m1 stop
American Airlines Logo
11:08 pm - 6:02 pmSFO-LSE
16h 54m1 stop
$871American Airlines
Find Deal
Mon, Aug 18 - Fri, Aug 22

American Airlines flights from La Crosse to San Francisco

Our best American Airlines deals on La Crosse to San Francisco flight tickets
American Airlines
Sep 17
LSE6:00 amLa Crosse
8h 31m
1 stop
SFO12:31 pmSan Francisco
Sep 23
SFO12:47 amSan Francisco
6h 32m
1 stop
LSE9:19 amLa Crosse
$457
Find similar
American Airlines
Sep 17
LSE6:21 pmLa Crosse
6h 48m
1 stop
SFO11:09 pmSan Francisco
Sep 24
SFO11:17 amSan Francisco
8h 47m
2 stops
LSE10:04 pmLa Crosse
$462
Find similar
American Airlines
Sep 17
LSE6:00 amLa Crosse
11h 09m
2 stops
SFO3:09 pmSan Francisco
Sep 24
SFO6:45 amSan Francisco
13h 19m
2 stops
LSE10:04 pmLa Crosse
$468
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from La Crosse to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2025.
Use the filters below to find and compare flights from La Crosse to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Wed 9/17

6:00 am-12:31 pm

1 stop8h 31m

San Francisco

Tue 9/23

12:47 am-9:19 am

1 stop6h 32m

$457

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Wed 9/17

6:21 pm-11:09 pm

1 stop6h 48m

San Francisco

Wed 9/24

11:17 am-10:04 pm

2 stops8h 47m

$462

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Wed 9/17

6:00 am-3:09 pm

2 stops11h 09m

San Francisco

Wed 9/24

6:45 am-10:04 pm

2 stops13h 19m

$468

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Wed 10/1

6:21 pm-11:09 pm

1 stop6h 48m

San Francisco

Mon 10/6

6:10 am-5:45 pm

1 stop9h 35m

$484

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Wed 10/1

6:00 am-3:09 pm

2 stops11h 09m

San Francisco

Mon 10/6

2:10 pm-11:26 pm

1 stop7h 16m

$490

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Wed 10/1

9:50 am-7:02 pm

2 stops11h 12m

San Francisco

Mon 10/6

9:16 am-11:26 pm

2 stops12h 10m

$495

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Thu 12/11

5:58 am-10:58 am

1 stop7h 00m

San Francisco

Sat 12/13

1:34 pm-9:45 pm

1 stop6h 11m

$574

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Thu 12/11

2:48 pm-9:57 pm

2 stops9h 09m

San Francisco

Sat 12/13

1:34 pm-9:45 pm

1 stop6h 11m

$580

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Thu 12/11

5:58 am-3:44 pm

2 stops11h 46m

San Francisco

Fri 12/12

12:27 am-2:21 pm

2 stops11h 54m

$585

La CrosseSan Francisco

LSE - SFO

LSESFO

La Crosse

Mon 8/18

6:32 pm-9:18 am

1 stop16h 46m

San Francisco

Fri 8/22

11:08 pm-6:02 pm

1 stop16h 54m

$871

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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How to get the cheapest flight ticket from La Crosse to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from La Crosse to San Francisco is on a Saturday when prices can be found for as low as $474. The most expensive day to fly to San Francisco is Wednesday, with ticket prices averaging around $619.

When to book flights from La Crosse to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from La Crosse to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap La Crosse to San Francisco (LSE to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from La Crosse to San Francisco

Best Price Found

$500

Fastest flight time

6h 48m

Direct flights

None

Airports in San Francisco

1 airport
The best one-way flight to San Francisco from La Crosse in the past 72 hours is $500. The best round-trip flight deal from La Crosse to San Francisco found on momondo in the last 72 hours is $457.
The fastest flight from La Crosse to San Francisco takes 6h 48m
There are no direct flights from La Crosse to San Francisco. Popular non-direct route for this connection is La Crosse Airport - San Francisco Airport.
There is 1 airport near San Francisco: San Francisco (SFO)
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  • How far is La Crosse to San Francisco by plane?

    There are 1670.6 mi between La Crosse and San Francisco. 6h 48m is a normal flight duration for this route.

  • When did momondo last update prices for flights from La Crosse Airport to San Francisco Airport?

    Prices for flights from La Crosse Airport to San Francisco Airport refresh daily.

  • How many operators does momondo search for flights from La Crosse Airport to San Francisco Airport?

  • How old do you have to be to fly from La Crosse Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from La Crosse Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents you'll need for your trip to San Francisco Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at San Francisco Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from La Crosse to San Francisco?

Best airlines flying from La Crosse to San Francisco

Compare and see reviews for airlines that fly from La Crosse to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $454Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Calistoga
Hayward
Sonoma
Bodega Bay
Roseville
Santa Clara
Big Sur
Daly City
Berkeley
Fremont
Walnut Creek
Half Moon Bay
South San Francisco
Vallejo
Redwood City
Sunnyvale
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from La Crosse to San Francisco?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from La Crosse to San Francisco for you.

Can I find flights from La Crosse to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from La Crosse which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from La Crosse to San Francisco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from La Crosse to San Francisco.

I’m not ready to book a flight from La Crosse to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from La Crosse are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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