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Cheap flights from Knoxville to Orlando from $159

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Orlando departing on 12/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Orlando

Cheap round-trip flights

Delta Logo
5:44 am - 10:26 amTYS-MLB
4h 42m1 stop
Delta Logo
6:50 pm - 11:07 pmMLB-TYS
4h 17m1 stop
$306Delta
Find Deal
Thu, Oct 16 - Sat, Oct 18
Delta Logo
5:45 am - 10:43 amTYS-MLB
4h 58m1 stop
Delta Logo
5:50 am - 9:44 amMLB-TYS
3h 54m1 stop
$369Delta
Find Deal
Wed, Oct 1 - Sun, Oct 5
American Airlines Logo
8:23 am - 12:17 pmTYS-MLB
3h 54m1 stop
American Airlines Logo
1:37 pm - 11:50 pmMLB-TYS
10h 13m2 stops
$374American Airlines
Find Deal
Wed, Oct 1 - Sun, Oct 5
Delta Logo
6:15 am - 10:26 amTYS-MLB
4h 11m1 stop
Delta Logo
6:50 pm - 11:07 pmMLB-TYS
4h 17m1 stop
$377Delta
Find Deal
Sat, Oct 11 - Wed, Oct 15
American Airlines Logo
6:30 am - 11:25 amTYS-MLB
4h 55m1 stop
American Airlines Logo
6:05 am - 12:59 pmMLB-TYS
6h 54m1 stop
$407American Airlines
Find Deal
Fri, Nov 21 - Thu, Nov 27
Delta Logo
5:25 am - 10:35 amTYS-MLB
5h 10m1 stop
Delta Logo
11:20 am - 2:46 pmMLB-TYS
3h 26m1 stop
$417Delta
Find Deal
Thu, Nov 13 - Sun, Nov 16
Delta Logo
5:25 am - 10:35 amTYS-MLB
5h 10m1 stop
Delta Logo
11:20 am - 2:46 pmMLB-TYS
3h 26m1 stop
$427Delta
Find Deal
Thu, Nov 13 - Sun, Nov 16
American Airlines Logo
6:30 am - 11:25 amTYS-MLB
4h 55m1 stop
American Airlines Logo
6:05 am - 12:43 pmMLB-TYS
30h 38m2 stops
$445American Airlines
Find Deal
Fri, Nov 21 - Thu, Nov 27
American Airlines Logo
2:52 pm - 6:41 pmTYS-MLB
3h 49m1 stop
American Airlines Logo
5:52 pm - 10:13 amMLB-TYS
16h 21m2 stops
$580American Airlines
Find Deal
Thu, Oct 16 - Sat, Oct 18
Delta Logo
5:44 am - 10:26 amTYS-MLB
4h 42m1 stop
Delta Logo
6:00 am - 9:20 amMLB-TYS
3h 20m1 stop
$628Delta
Find Deal
Mon, Oct 27 - Fri, Oct 31

American Airlines flights from Knoxville to Melbourne, Florida

Our best American Airlines deals on Knoxville to Melbourne, Florida flight tickets
American Airlines
Oct 1
TYS8:23 amKnoxville McGhee Tyson
3h 54m
1 stop
MLB12:17 pmMelbourne
Oct 5
MLB1:37 pmMelbourne
10h 13m
2 stops
TYS11:50 pmKnoxville McGhee Tyson
$374
Find similar
American Airlines
Nov 21
TYS6:30 amKnoxville McGhee Tyson
4h 55m
1 stop
MLB11:25 amMelbourne
Nov 27
MLB6:05 amMelbourne
6h 54m
1 stop
TYS12:59 pmKnoxville McGhee Tyson
$407
Find similar
American Airlines
Sep 20
TYS5:05 amKnoxville McGhee Tyson
7h 12m
1 stop
MLB12:17 pmMelbourne
Sep 24
MLB7:27 amMelbourne
4h 23m
1 stop
TYS11:50 amKnoxville McGhee Tyson
$431
Find similar

Delta flights from Knoxville to Melbourne, Florida

Our best Delta deals on Knoxville to Melbourne, Florida flight tickets
Delta
Oct 16
TYS5:44 amKnoxville McGhee Tyson
4h 42m
1 stop
MLB10:26 amMelbourne
Oct 18
MLB6:50 pmMelbourne
4h 17m
1 stop
TYS11:07 pmKnoxville McGhee Tyson
$306
Find similar
Delta
Oct 1
TYS5:45 amKnoxville McGhee Tyson
4h 58m
1 stop
MLB10:43 amMelbourne
Oct 5
MLB5:50 amMelbourne
3h 54m
1 stop
TYS9:44 amKnoxville McGhee Tyson
$369
Find similar
Delta
Oct 11
TYS6:15 amKnoxville McGhee Tyson
4h 11m
1 stop
MLB10:26 amMelbourne
Oct 15
MLB6:50 pmMelbourne
4h 17m
1 stop
TYS11:07 pmKnoxville McGhee Tyson
$377
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Melbourne, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 19, 2025.
Use the filters below to find and compare flights from Knoxville to Melbourne, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Thu 10/16

5:44 am-10:26 am

1 stop4h 42m

Melbourne

Sat 10/18

6:50 pm-11:07 pm

1 stop4h 17m

$306

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Wed 10/1

5:45 am-10:43 am

1 stop4h 58m

Melbourne

Sun 10/5

5:50 am-9:44 am

1 stop3h 54m

$369

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Wed 10/1

8:23 am-12:17 pm

1 stop3h 54m

Melbourne

Sun 10/5

1:37 pm-11:50 pm

2 stops10h 13m

$374

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Sat 10/11

6:15 am-10:26 am

1 stop4h 11m

Melbourne

Wed 10/15

6:50 pm-11:07 pm

1 stop4h 17m

$377

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Fri 11/21

6:30 am-11:25 am

1 stop4h 55m

Melbourne

Thu 11/27

6:05 am-12:59 pm

1 stop6h 54m

$407

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Thu 11/13

5:25 am-10:35 am

1 stop5h 10m

Melbourne

Sun 11/16

11:20 am-2:46 pm

1 stop3h 26m

$417

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Thu 11/13

5:25 am-10:35 am

1 stop5h 10m

Melbourne

Sun 11/16

11:20 am-2:46 pm

1 stop3h 26m

$427

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Fri 11/21

6:30 am-11:25 am

1 stop4h 55m

Melbourne

Thu 11/27

6:05 am-12:43 pm

2 stops30h 38m

$445

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Thu 10/16

2:52 pm-6:41 pm

1 stop3h 49m

Melbourne

Sat 10/18

5:52 pm-10:13 am

2 stops16h 21m

$580

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Mon 10/27

5:44 am-10:26 am

1 stop4h 42m

Melbourne

Fri 10/31

6:00 am-9:20 am

1 stop3h 20m

$628

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Melbourne, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Melbourne, Florida?

In general, May is the cheapest month to fly from Knoxville to Melbourne, Florida. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $273. If you aren’t able to travel during the month of May, then book flights to Melbourne, Florida from Knoxville during August instead. Flights to Melbourne, Florida in August, while not as cheap as those in May, still average around $298.

What is the cheapest day to depart on your flight to Melbourne, Florida?

The cheapest day to depart on your flight to Melbourne, Florida is on a Monday when prices can be found for as low as $328. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $620.

What is the cheapest time of day to depart on your flight to Melbourne, Florida?

According to our data, the cheapest time of day to fly to Melbourne, Florida is in the evening. momondo users have found flights departing from Knoxville to Melbourne, Florida in the evening for as low as $416. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights in the afternoon are often more expensive with an average ticket price of $453.

When to book flights from Knoxville to Melbourne, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Melbourne, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Melbourne, Florida (TYS to MLB) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Melbourne, Florida

Direct flights

None
There are no direct flights from Knoxville to Melbourne, Florida. There are no popular flight routes from Knoxville to Melbourne, Florida.
Search flight deals

  • How far is Knoxville McGhee Tyson to Melbourne by plane?

    A flight from Knoxville McGhee Tyson to Melbourne will travel around 577.3 mi. In terms of flight time, this usually takes a little over 3h 49m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Melbourne Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Melbourne Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Melbourne Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Melbourne Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Melbourne Airport.

  • What documentation or ID do you need to fly to Melbourne Airport?

    The required travel and health documents for your Melbourne Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Melbourne Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Melbourne, Florida?

Best airlines flying from Knoxville to Melbourne, Florida

Compare and see reviews for airlines that fly from Knoxville to Melbourne, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $273Free CancellationRating
7.9
7,964 reviews
Search Delta flights
American AirlinesPriceFrom $328Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Melbourne?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Melbourne. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Melbourne with flexible booking policies on momondo?

momondo does allow users to show only those flights to Melbourne from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to Melbourne?

Once you have performed a search for Knoxville to Melbourne flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to Melbourne right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Melbourne flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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