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Cheap flights from Knoxville to Orlando from $168

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Orlando departing on 4/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Knoxville to Orlando

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:57 pm - 12:14 am
TYS
-
MLB
6h 17m
1 stop
American Airlines Logo
5:35 pm - 10:24 pm
MLB
-
TYS
4h 49m
1 stop
$295American Airlines
Sat, Apr 11 - Sat, Apr 25
American Airlines Logo
6:54 am - 11:03 am
TYS
-
MLB
4h 09m
1 stop
American Airlines Logo
5:35 pm - 10:56 pm
MLB
-
TYS
5h 21m
1 stop
$317American Airlines
Tue, Apr 7 - Tue, Apr 14
American Airlines Logo
6:07 pm - 11:59 pm
TYS
-
MLB
5h 52m
1 stop
American Airlines Logo
6:02 am - 10:36 am
MLB
-
TYS
4h 34m
1 stop
$335American Airlines
Fri, May 22 - Fri, May 29
Delta Logo
5:40 am - 10:40 am
TYS
-
MLB
5h 00m
1 stop
Delta Logo
6:43 pm - 11:54 pm
MLB
-
TYS
5h 11m
1 stop
$355Delta
Sat, Apr 11 - Sat, Apr 25
Delta Logo
5:40 am - 10:40 am
TYS
-
MLB
5h 00m
1 stop
Delta Logo
6:39 pm - 11:57 pm
MLB
-
TYS
5h 18m
1 stop
$357Delta
Sun, Mar 29 - Wed, Apr 1
Delta Logo
5:40 am - 10:40 am
TYS
-
MLB
5h 00m
1 stop
Delta Logo
6:39 pm - 11:57 pm
MLB
-
TYS
5h 18m
1 stop
$375Delta
Sun, Mar 22 - Thu, Mar 26
American Airlines Logo
5:00 am - 11:23 am
TYS
-
MLB
6h 23m
1 stop
American Airlines Logo
5:35 pm - 10:24 pm
MLB
-
TYS
4h 49m
1 stop
$378American Airlines
Fri, May 1 - Wed, May 6
Delta Logo
5:40 am - 10:40 am
TYS
-
MLB
5h 00m
1 stop
Delta Logo
6:39 pm - 11:57 pm
MLB
-
TYS
5h 18m
1 stop
$387Delta
Sun, Mar 29 - Wed, Apr 1
Delta Logo
5:40 am - 10:40 am
TYS
-
MLB
5h 00m
1 stop
Delta Logo
6:39 pm - 11:57 pm
MLB
-
TYS
5h 18m
1 stop
$392Delta
Sun, Mar 29 - Wed, Apr 1
Delta Logo
6:38 pm - 10:56 pm
TYS
-
MLB
4h 18m
1 stop
Delta Logo
6:39 pm - 11:57 pm
MLB
-
TYS
5h 18m
1 stop
$409Delta
Sun, Mar 29 - Tue, Mar 31

Delta flights from Knoxville to Melbourne, Florida

Our best Delta deals on Knoxville to Melbourne, Florida flight tickets
Delta
Aug 7
TYS5:57 pmKnoxville McGhee Tyson
4h 49m
1 stop
MLB10:46 pmMelbourne
Aug 10
MLB6:35 pmMelbourne
5h 12m
1 stop
TYS11:47 pmKnoxville McGhee Tyson
$345
Delta
Apr 11
TYS5:40 amKnoxville McGhee Tyson
5h 00m
1 stop
MLB10:40 amMelbourne
Apr 25
MLB6:43 pmMelbourne
5h 11m
1 stop
TYS11:54 pmKnoxville McGhee Tyson
$355
Delta
Mar 29
TYS5:40 amKnoxville McGhee Tyson
5h 00m
1 stop
MLB10:40 amMelbourne
Apr 1
MLB6:39 pmMelbourne
5h 18m
1 stop
TYS11:57 pmKnoxville McGhee Tyson
$357

American Airlines flights from Knoxville to Melbourne, Florida

Our best American Airlines deals on Knoxville to Melbourne, Florida flight tickets
American Airlines
Apr 11
TYS5:57 pmKnoxville McGhee Tyson
6h 17m
1 stop
MLB12:14 amMelbourne
Apr 25
MLB5:35 pmMelbourne
4h 49m
1 stop
TYS10:24 pmKnoxville McGhee Tyson
$295
American Airlines
Apr 7
TYS6:54 amKnoxville McGhee Tyson
4h 09m
1 stop
MLB11:03 amMelbourne
Apr 14
MLB5:35 pmMelbourne
5h 21m
1 stop
TYS10:56 pmKnoxville McGhee Tyson
$317
American Airlines
May 22
TYS6:07 pmKnoxville McGhee Tyson
5h 52m
1 stop
MLB11:59 pmMelbourne
May 29
MLB6:02 amMelbourne
4h 34m
1 stop
TYS10:36 amKnoxville McGhee Tyson
$335

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Melbourne, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Knoxville to Melbourne, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Sat 4/11

5:57 pm-12:14 am

1 stop6h 17m

Melbourne

Sat 4/25

5:35 pm-10:24 pm

1 stop4h 49m

$295
Quickest round-trip

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Tue 4/7

6:54 am-11:03 am

1 stop4h 09m

Melbourne

Tue 4/14

5:35 pm-10:56 pm

1 stop5h 21m

$317

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Fri 5/22

6:07 pm-11:59 pm

1 stop5h 52m

Melbourne

Fri 5/29

6:02 am-10:36 am

1 stop4h 34m

$335

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Sat 4/11

5:40 am-10:40 am

1 stop5h 00m

Melbourne

Sat 4/25

6:43 pm-11:54 pm

1 stop5h 11m

$355

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Sun 3/29

5:40 am-10:40 am

1 stop5h 00m

Melbourne

Wed 4/1

6:39 pm-11:57 pm

1 stop5h 18m

$357

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Sun 3/22

5:40 am-10:40 am

1 stop5h 00m

Melbourne

Thu 3/26

6:39 pm-11:57 pm

1 stop5h 18m

$375

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Fri 5/1

5:00 am-11:23 am

1 stop6h 23m

Melbourne

Wed 5/6

5:35 pm-10:24 pm

1 stop4h 49m

$378

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Sun 3/29

5:40 am-10:40 am

1 stop5h 00m

Melbourne

Wed 4/1

6:39 pm-11:57 pm

1 stop5h 18m

$387

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Sun 3/29

5:40 am-10:40 am

1 stop5h 00m

Melbourne

Wed 4/1

6:39 pm-11:57 pm

1 stop5h 18m

$392

KnoxvilleMelbourne

TYS - MLB

TYSMLB

Knoxville McGhee Tyson

Sun 3/29

6:38 pm-10:56 pm

1 stop4h 18m

Melbourne

Tue 3/31

6:39 pm-11:57 pm

1 stop5h 18m

$409

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Melbourne, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Knoxville McGhee Tyson to Melbourne?

Delta is the most popular carrier operating from Knoxville McGhee Tyson to Melbourne

What airlines fly to Melbourne, Florida?

Allegiant Air, American Airlines and Delta are the top three most popular airlines that fly to Melbourne, Florida from Knoxville according to our data. Allegiant Air is the first choice among our users, with 61% of people opting to fly with this airline when traveling to Melbourne, Florida. Keep in mind that there are 7 different airlines that fly to Melbourne, Florida on a routine basis, so you have a few additional options to choose from.

When to book flights from Knoxville to Melbourne, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Melbourne, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Melbourne, Florida (TYS to MLB) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Melbourne, Florida

Fastest flight time

4h 40m

Direct flights

None
The fastest flight from Knoxville to Melbourne, Florida takes 4h 40m
There are no direct flights from Knoxville to Melbourne, Florida. There are no popular flight routes from Knoxville to Melbourne, Florida.
Search flight deals

  • How far is Knoxville McGhee Tyson to Melbourne by plane?

    A flight from Knoxville McGhee Tyson to Melbourne will travel around 577.3 mi. In terms of flight time, this usually takes a little over 4h 40m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Melbourne Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Melbourne Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Melbourne Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Melbourne Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Melbourne Airport.

  • What documentation or ID do you need to fly to Melbourne Airport?

    The required travel and health documents for your Melbourne Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Melbourne Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Melbourne, Florida?

Best airlines flying from Knoxville to Melbourne, Florida

Compare and see reviews for airlines that fly from Knoxville to Melbourne, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $273Free CancellationRating
7.9
8,278 reviews
Search Delta flights
American AirlinesPriceFrom $298Free CancellationRating
7.1
11,419 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Melbourne?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Melbourne. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Melbourne with flexible booking policies on momondo?

momondo does allow users to show only those flights to Melbourne from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to Melbourne?

Once you have performed a search for Knoxville to Melbourne flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to Melbourne right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Melbourne flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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