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Cheap flights from Harrisburg to San Francisco from $225

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Harrisburg to San Francisco departing on 10/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Harrisburg to San Francisco

Cheap round-trip flights

Delta Logo
6:00 am - 1:33 pmMDT-SFO
10h 33m1 stop
Delta Logo
11:25 am - 11:00 pmSFO-MDT
8h 35m1 stop
$309Delta
Find Deal
Fri, Oct 31 - Tue, Nov 4
American Airlines Logo
6:44 am - 3:18 pmMDT-SFO
11h 34m2 stops
American Airlines Logo
11:15 pm - 11:12 amSFO-MDT
8h 57m1 stop
$314American Airlines
Find Deal
Fri, Oct 31 - Mon, Nov 3
American Airlines Logo
12:54 pm - 8:30 pmMDT-SFO
10h 36m1 stop
American Airlines Logo
12:27 am - 10:53 amSFO-MDT
7h 26m1 stop
$339American Airlines
Find Deal
Wed, Nov 12 - Sat, Nov 15
American Airlines Logo
5:40 am - 1:29 pmMDT-SFO
10h 49m2 stops
American Airlines Logo
12:27 am - 10:53 amSFO-MDT
7h 26m1 stop
$344American Airlines
Find Deal
Wed, Nov 12 - Sat, Nov 15
Delta Logo
6:10 am - 10:33 amMDT-SFO
7h 23m1 stop
Delta Logo
5:50 am - 11:08 pmSFO-MDT
14h 18m2 stops
$347Delta
Find Deal
Fri, Oct 31 - Tue, Nov 4
Delta Logo
6:00 am - 1:33 pmMDT-SFO
10h 33m1 stop
Delta Logo
6:00 am - 11:00 pmSFO-MDT
14h 00m2 stops
$371Delta
Find Deal
Fri, Oct 31 - Sat, Nov 1
Delta Logo
6:00 am - 1:33 pmMDT-SFO
10h 33m1 stop
Delta Logo
5:55 am - 4:12 pmSFO-MDT
7h 17m1 stop
$374Delta
Find Deal
Fri, Oct 31 - Sun, Nov 2
United Airlines Logo
6:30 am - 1:24 pmMDT-SFO
9h 54m1 stop
United Airlines Logo
5:30 am - 6:40 pmSFO-MDT
10h 10m1 stop
$409United Airlines
Find Deal
Tue, Mar 3 - Sat, Mar 7
United Airlines Logo
6:30 am - 5:38 pmMDT-SFO
14h 08m2 stops
United Airlines Logo
9:20 pm - 9:35 amSFO-MDT
9h 15m1 stop
$414United Airlines
Find Deal
Fri, Oct 31 - Sun, Nov 2
United Airlines Logo
10:25 am - 3:23 pmMDT-SFO
7h 58m1 stop
United Airlines Logo
6:30 am - 6:59 pmSFO-MDT
9h 29m1 stop
$439United Airlines
Find Deal
Wed, Oct 15 - Tue, Oct 21

United Airlines flights from Harrisburg to San Francisco

Our best United Airlines deals on Harrisburg to San Francisco flight tickets
United Airlines
Mar 3
MDT6:30 amHarrisburg
9h 54m
1 stop
SFO1:24 pmSan Francisco
Mar 7
SFO5:30 amSan Francisco
10h 10m
1 stop
MDT6:40 pmHarrisburg
$409
Find similar
United Airlines
Oct 31
MDT6:30 amHarrisburg
14h 08m
2 stops
SFO5:38 pmSan Francisco
Nov 2
SFO9:20 pmSan Francisco
9h 15m
1 stop
MDT9:35 amHarrisburg
$414
Find similar
United Airlines
Oct 15
MDT10:25 amHarrisburg
7h 58m
1 stop
SFO3:23 pmSan Francisco
Oct 21
SFO6:30 amSan Francisco
9h 29m
1 stop
MDT6:59 pmHarrisburg
$439
Find similar

Delta flights from Harrisburg to San Francisco

Our best Delta deals on Harrisburg to San Francisco flight tickets
Delta
Oct 31
MDT6:00 amHarrisburg
10h 33m
1 stop
SFO1:33 pmSan Francisco
Nov 4
SFO11:25 amSan Francisco
8h 35m
1 stop
MDT11:00 pmHarrisburg
$309
Find similar
Delta
Oct 31
MDT6:10 amHarrisburg
7h 23m
1 stop
SFO10:33 amSan Francisco
Nov 4
SFO5:50 amSan Francisco
14h 18m
2 stops
MDT11:08 pmHarrisburg
$347
Find similar
Delta
Oct 31
MDT6:00 amHarrisburg
10h 33m
1 stop
SFO1:33 pmSan Francisco
Nov 1
SFO6:00 amSan Francisco
14h 00m
2 stops
MDT11:00 pmHarrisburg
$371
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Harrisburg to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Harrisburg to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 10/31

6:00 am-1:33 pm

1 stop10h 33m

San Francisco

Tue 11/4

11:25 am-11:00 pm

1 stop8h 35m

$309

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 10/31

6:44 am-3:18 pm

2 stops11h 34m

San Francisco

Mon 11/3

11:15 pm-11:12 am

1 stop8h 57m

$314

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Wed 11/12

12:54 pm-8:30 pm

1 stop10h 36m

San Francisco

Sat 11/15

12:27 am-10:53 am

1 stop7h 26m

$339

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Wed 11/12

5:40 am-1:29 pm

2 stops10h 49m

San Francisco

Sat 11/15

12:27 am-10:53 am

1 stop7h 26m

$344

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 10/31

6:10 am-10:33 am

1 stop7h 23m

San Francisco

Tue 11/4

5:50 am-11:08 pm

2 stops14h 18m

$347

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 10/31

6:00 am-1:33 pm

1 stop10h 33m

San Francisco

Sat 11/1

6:00 am-11:00 pm

2 stops14h 00m

$371

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 10/31

6:00 am-1:33 pm

1 stop10h 33m

San Francisco

Sun 11/2

5:55 am-4:12 pm

1 stop7h 17m

$374

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Tue 3/3

6:30 am-1:24 pm

1 stop9h 54m

San Francisco

Sat 3/7

5:30 am-6:40 pm

1 stop10h 10m

$409

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Fri 10/31

6:30 am-5:38 pm

2 stops14h 08m

San Francisco

Sun 11/2

9:20 pm-9:35 am

1 stop9h 15m

$414

HarrisburgSan Francisco

MDT - SFO

MDTSFO

Harrisburg

Wed 10/15

10:25 am-3:23 pm

1 stop7h 58m

San Francisco

Tue 10/21

6:30 am-6:59 pm

1 stop9h 29m

$439

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Harrisburg to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of September, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $393.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Harrisburg to San Francisco is on a Saturday when prices can be found for as low as $393. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $658.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Harrisburg to San Francisco flights are usually those with departure times at noon. Our users have found flights to San Francisco at noon for as low as $369. Flights in the morning are often more expensive with an average ticket price of $478.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Harrisburg when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $469 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Harrisburg for as low as $306 on momondo.

How have Harrisburg to San Francisco flight prices changed over time?

When to book flights from Harrisburg to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Harrisburg to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Harrisburg to San Francisco (MDT to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to San Francisco

Direct flights

None
There are no direct flights from Harrisburg to San Francisco. There are no popular flight routes from Harrisburg to San Francisco.
Search flight deals

  • How far is Harrisburg to San Francisco by plane?

    San Francisco is 2421.0 mi away from Harrisburg. Typically, this will take 7h 23m by plane in normal conditions.

  • When did momondo last update prices for flights from Harrisburg Airport to San Francisco Airport?

    Prices for flights from Harrisburg Airport to San Francisco Airport are updated daily.

  • How many operators does momondo search for flights from Harrisburg Airport to San Francisco Airport?

  • How old do you have to be to fly from Harrisburg Airport to San Francisco Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Harrisburg Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Harrisburg to San Francisco?

Best airlines flying from Harrisburg to San Francisco

Compare and see reviews for airlines that fly from Harrisburg to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $308Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $308Free CancellationRating
7.4
8,924 reviews
Search United Airlines flights
DeltaPriceFrom $308Free CancellationRating
7.9
7,957 reviews
Search Delta flights
FrontierPriceFrom $350Free CancellationRating
5.8
3,174 reviews
Search Frontier flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Calistoga
Bodega Bay
Roseville
Hayward
Big Sur
Santa Clara
Daly City
Fremont
Berkeley
Half Moon Bay
Walnut Creek
Vallejo
Redwood City
Salinas
South San Francisco
Fairfield

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to San Francisco?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Francisco from Harrisburg.

Can I find flights from Harrisburg to San Francisco with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Francisco from Harrisburg with this policy.

How can momondo help me find flights from Harrisburg to San Francisco?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Harrisburg to San Francisco.

I’m not ready to book a flight from Harrisburg to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Harrisburg to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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