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Cheap flights from Guayaquil to San Diego from $327

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Guayaquil to San Diego departing on 11/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Guayaquil to San Diego

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
8:27 am - 5:15 pmGYE  Guayaquil Jose Joaquin de Olmedo-SAN San Diego
11h 48m1 stop Panama City Tocumen Intl
Copa Airlines Logo
10:00 pm - 8:57 pmSAN  San Diego-GYE Guayaquil Jose Joaquin de Olmedo
19h 57m1 stop Panama City Tocumen Intl
$576Copa Airlines
Mon, Nov 23 - Mon, Nov 30
Copa Airlines Logo
8:27 am - 5:15 pmGYE  Guayaquil Jose Joaquin de Olmedo-SAN San Diego
11h 48m1 stop Panama City Tocumen Intl
Copa Airlines Logo
10:00 pm - 8:57 pmSAN  San Diego-GYE Guayaquil Jose Joaquin de Olmedo
19h 57m1 stop Panama City Tocumen Intl
$576Copa Airlines
Mon, Nov 23 - Mon, Nov 30
Copa Airlines Logo
6:28 pm - 6:29 pmGYE  Guayaquil Jose Joaquin de Olmedo-SAN San Diego
26h 01m1 stop Panama City Tocumen Intl
Copa Airlines Logo
10:00 pm - 1:34 pmSAN  San Diego-GYE Guayaquil Jose Joaquin de Olmedo
13h 34m1 stop Panama City Tocumen Intl
$576Copa Airlines
Tue, Sep 15 - Fri, Sep 25
Multiple Airlines Logo
8:00 pm - 2:50 pmGYE  Guayaquil Jose Joaquin de Olmedo-SAN San Diego
20h 50m1 stop New York John F Kennedy Intl
Multiple Airlines Logo
10:24 am - 7:45 amSAN  San Diego-GYE Guayaquil Jose Joaquin de Olmedo
19h 21m1 stop New York John F Kennedy Intl
$583Multiple Airlines
Sun, Sep 20 - Tue, Oct 6
Multiple Airlines Logo
8:00 pm - 9:08 amGYE  Guayaquil Jose Joaquin de Olmedo-SAN San Diego
15h 08m1 stop New York John F Kennedy Intl
Multiple Airlines Logo
2:20 pm - 10:40 amSAN  San Diego-GYE Guayaquil Jose Joaquin de Olmedo
18h 20m1 stop New York John F Kennedy Intl
$592Multiple Airlines
Tue, Sep 29 - Thu, Oct 1
Multiple Airlines Logo
3:30 am - 7:35 pmGYE  Guayaquil Jose Joaquin de Olmedo-SAN San Diego
18h 05m2 stops Bogotá El Dorado New York John F Kennedy Intl
Multiple Airlines Logo
10:24 am - 7:45 amSAN  San Diego-GYE Guayaquil Jose Joaquin de Olmedo
19h 21m1 stop New York John F Kennedy Intl
$607Multiple Airlines
Sat, Sep 19 - Tue, Oct 6
Multiple Airlines Logo
3:30 am - 8:01 pmGYE  Guayaquil Jose Joaquin de Olmedo-SAN San Diego
18h 31m2 stops Bogotá El Dorado New York John F Kennedy Intl
Multiple Airlines Logo
2:20 pm - 7:45 amSAN  San Diego-GYE Guayaquil Jose Joaquin de Olmedo
15h 25m1 stop New York John F Kennedy Intl
$616Multiple Airlines
Mon, Sep 28 - Thu, Oct 1
Multiple Airlines Logo
4:05 pm - 12:54 pmGYE  Guayaquil Jose Joaquin de Olmedo-SAN San Diego
23h 49m1 stop New York John F Kennedy Intl
Multiple Airlines Logo
9:56 pm - 7:55 amSAN  San Diego-GYE Guayaquil Jose Joaquin de Olmedo
30h 59m1 stop New York John F Kennedy Intl
$618Multiple Airlines
Mon, Nov 23 - Mon, Nov 30
Multiple Airlines Logo
8:00 pm - 2:50 pmGYE  Guayaquil Jose Joaquin de Olmedo-SAN San Diego
20h 50m1 stop New York John F Kennedy Intl
Multiple Airlines Logo
10:23 am - 7:45 amSAN  San Diego-GYE Guayaquil Jose Joaquin de Olmedo
19h 22m1 stop New York John F Kennedy Intl
$621Multiple Airlines
Fri, Sep 18 - Fri, Sep 25
Multiple Airlines Logo
3:30 am - 9:08 amGYE  Guayaquil Jose Joaquin de Olmedo-SAN San Diego
31h 38m2 stops Bogotá El Dorado New York John F Kennedy Intl
Multiple Airlines Logo
2:20 pm - 11:30 pmSAN  San Diego-GYE Guayaquil Jose Joaquin de Olmedo
31h 10m2 stops New York John F Kennedy Intl Bogotá El Dorado
$623Multiple Airlines
Mon, Sep 14 - Fri, Sep 25

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JetBlue flights from Guayaquil to San Diego

Our best JetBlue deals on Guayaquil to San Diego flight tickets
JetBlue
Aug 24
GYE4:47 pmGuayaquil Jose Joaquin de Olmedo
20h 05m
1 stop
SAN10:52 amSan Diego
Sep 3
SAN8:30 pmSan Diego
13h 32m
1 stop
GYE12:02 pmGuayaquil Jose Joaquin de Olmedo
$753
JetBlue
Aug 24
GYE4:47 pmGuayaquil Jose Joaquin de Olmedo
20h 05m
1 stop
SAN10:52 amSan Diego
Sep 3
SAN8:30 pmSan Diego
13h 32m
1 stop
GYE12:02 pmGuayaquil Jose Joaquin de Olmedo
$788
JetBlue
Aug 20
GYE4:47 pmGuayaquil Jose Joaquin de Olmedo
20h 05m
1 stop
SAN10:52 amSan Diego
Aug 27
SAN8:30 pmSan Diego
13h 32m
1 stop
GYE12:02 pmGuayaquil Jose Joaquin de Olmedo
$2,388

United Airlines flights from Guayaquil to San Diego

Our best United Airlines deals on Guayaquil to San Diego flight tickets
United Airlines
Aug 23
GYE2:37 pmGuayaquil Jose Joaquin de Olmedo
46h 18m
2 stops
SAN10:55 amSan Diego
Aug 26
SAN3:04 pmSan Diego
30h 34m
2 stops
GYE11:38 pmGuayaquil Jose Joaquin de Olmedo
$844
United Airlines
Oct 15
GYE8:24 amGuayaquil Jose Joaquin de Olmedo
30h 53m
2 stops
SAN1:17 pmSan Diego
Oct 19
SAN4:46 pmSan Diego
28h 51m
2 stops
GYE11:37 pmGuayaquil Jose Joaquin de Olmedo
$860

momondo Fare Finder

 
Customize your flight search to find flights from Guayaquil to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 8, 2026.
Use the filters below to find and compare flights from Guayaquil to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

GuayaquilSan Diego

GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego

GYESAN

Guayaquil Jose Joaquin de Olmedo

Mon 11/23

8:27 am-5:15 pm

1 stop11h 48m

San Diego

Mon 11/30

10:00 pm-8:57 pm

1 stop19h 57m

$576

GuayaquilSan Diego

GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego

GYESAN

Guayaquil Jose Joaquin de Olmedo

Mon 11/23

8:27 am-5:15 pm

1 stop11h 48m

San Diego

Mon 11/30

10:00 pm-8:57 pm

1 stop19h 57m

$576

GuayaquilSan Diego

GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego

GYESAN

Guayaquil Jose Joaquin de Olmedo

Tue 9/15

6:28 pm-6:29 pm

1 stop26h 01m

San Diego

Fri 9/25

10:00 pm-1:34 pm

1 stop13h 34m

$576

GuayaquilSan Diego

GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego

GYESAN

Guayaquil Jose Joaquin de Olmedo

Sun 9/20

8:00 pm-2:50 pm

1 stop20h 50m

San Diego

Tue 10/6

10:24 am-7:45 am

1 stop19h 21m

$583

GuayaquilSan Diego

GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego

GYESAN

Guayaquil Jose Joaquin de Olmedo

Tue 9/29

8:00 pm-9:08 am

1 stop15h 08m

San Diego

Thu 10/1

2:20 pm-10:40 am

1 stop18h 20m

$592

GuayaquilSan Diego

GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego

GYESAN

Guayaquil Jose Joaquin de Olmedo

Sat 9/19

3:30 am-7:35 pm

2 stops18h 05m

San Diego

Tue 10/6

10:24 am-7:45 am

1 stop19h 21m

$607

GuayaquilSan Diego

GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego

GYESAN

Guayaquil Jose Joaquin de Olmedo

Mon 9/28

3:30 am-8:01 pm

2 stops18h 31m

San Diego

Thu 10/1

2:20 pm-7:45 am

1 stop15h 25m

$616

GuayaquilSan Diego

GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego

GYESAN

Guayaquil Jose Joaquin de Olmedo

Mon 11/23

4:05 pm-12:54 pm

1 stop23h 49m

San Diego

Mon 11/30

9:56 pm-7:55 am

1 stop30h 59m

$618

GuayaquilSan Diego

GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego

GYESAN

Guayaquil Jose Joaquin de Olmedo

Fri 9/18

8:00 pm-2:50 pm

1 stop20h 50m

San Diego

Fri 9/25

10:23 am-7:45 am

1 stop19h 22m

$621

GuayaquilSan Diego

GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego

GYESAN

Guayaquil Jose Joaquin de Olmedo

Mon 9/14

3:30 am-9:08 am

2 stops31h 38m

San Diego

Fri 9/25

2:20 pm-11:30 pm

2 stops31h 10m

$623

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Guayaquil to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of January, then departing from Guayaquil during the month October is also very affordable. Most momondo users find prices during this month for around $505.

Can stopping save me money on Guayaquil to San Diego flights?

You could potentially save up to 41% on your flight if you consider stops on a Guayaquil to San Diego flight.

When to book flights from Guayaquil to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Guayaquil to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Guayaquil to San Diego (GYE to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Guayaquil to San Diego

Fastest flight time

11h 48m

Direct flights

None
The fastest flight from Guayaquil to San Diego takes 11h 48m
There are no direct flights from Guayaquil to San Diego. There are no popular flight routes from Guayaquil to San Diego.
Search flight deals

Frequently asked questions about flying from Guayaquil to San Diego

  • How far is Guayaquil Jose Joaquin de Olmedo to San Diego by plane?

    Guayaquil Jose Joaquin de Olmedo and San Diego are 3423.3 mi apart from one another. Flights usually cover this in 11h 48m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to San Diego Airport?

    Prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to San Diego Airport refresh daily.

  • How many operators does momondo search for flights from Guayaquil Jose Joaquin de Olmedo Airport to San Diego Airport?

  • How old do you have to be to fly from Guayaquil Jose Joaquin de Olmedo Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Guayaquil Jose Joaquin de Olmedo Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The required travel and health documents for your San Diego Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Diego Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Guayaquil to San Diego?

Best airlines flying from Guayaquil to San Diego

Compare and see reviews for airlines that fly from Guayaquil to San Diego with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $556Free CancellationRating
7.6
1,563 reviews
Search Copa Airlines flights

Traveling to a place near San Diego?

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Coronado
El Cajon
National City
Julian
La Mesa
Poway
San Ysidro
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Borrego Springs
Santee
Lemon Grove
Alpine

Why use momondo?

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Can I find flights from Guayaquil to San Diego with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Diego from Guayaquil which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Guayaquil to San Diego?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Diego from Guayaquil.

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Of course. momondo tracks the price of Guayaquil to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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