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Cheap flights from Fort Myers to San Diego from $110

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Fort Myers to San Diego departing on 10/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Fort Myers to San Diego

Cheap round-trip flights

Frontier Logo
7:24 pm - 11:53 pmRSW-SAN
31h 29m2 stops
Frontier Logo
6:35 am - 6:51 pmSAN-RSW
33h 16m2 stops
$279Frontier
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Sun, Sep 28 - Thu, Oct 2
JetBlue Logo
9:55 am - 7:34 pmRSW-SAN
12h 39m1 stop
JetBlue Logo
10:25 am - 10:54 pmSAN-RSW
9h 29m1 stop
$295JetBlue
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Tue, Mar 3 - Wed, Mar 4
Delta Logo
2:13 pm - 9:53 pmRSW-SAN
10h 40m1 stop
Delta Logo
7:25 am - 9:12 pmSAN-RSW
10h 47m1 stop
$317Delta
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Tue, Oct 14 - Tue, Oct 21
American Airlines Logo
11:08 am - 6:06 pmRSW-SAN
9h 58m1 stop
American Airlines Logo
10:31 pm - 9:08 amSAN-RSW
7h 37m1 stop
$320American Airlines
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Wed, Oct 8 - Sun, Oct 12
United Airlines Logo
5:14 pm - 11:41 pmRSW-SAN
9h 27m2 stops
United Airlines Logo
9:01 am - 7:55 pmSAN-RSW
7h 54m1 stop
$322United Airlines
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Tue, Oct 14 - Tue, Oct 21
Delta Logo
8:00 am - 2:32 pmRSW-SAN
9h 32m1 stop
Delta Logo
10:20 pm - 11:26 amSAN-RSW
10h 06m1 stop
$327Delta
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Wed, Oct 22 - Sat, Oct 25
United Airlines Logo
3:45 pm - 11:41 pmRSW-SAN
10h 56m2 stops
United Airlines Logo
6:15 am - 3:56 pmSAN-RSW
6h 41m1 stop
$332United Airlines
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Wed, Oct 22 - Sat, Oct 25
Southwest Logo
10:20 am - 6:40 pmRSW-SAN
11h 20m2 stops
Southwest Logo
8:30 am - 9:35 pmSAN-RSW
10h 05m2 stops
$344Southwest
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Wed, Oct 22 - Sat, Oct 25
American Airlines Logo
11:56 am - 6:40 pmRSW-SAN
9h 44m1 stop
American Airlines Logo
6:23 am - 8:06 pmSAN-RSW
10h 43m1 stop
$351American Airlines
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Mon, Feb 2 - Thu, Feb 5
Southwest Logo
4:15 pm - 11:05 pmRSW-SAN
9h 50m1 stop
Southwest Logo
7:30 am - 7:35 pmSAN-RSW
9h 05m2 stops
$356Southwest
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Mon, Feb 2 - Thu, Feb 5

Southwest flights from Fort Myers to San Diego

Our best Southwest deals on Fort Myers to San Diego flight tickets
Southwest
Oct 22
RSW10:20 amFort Myers SW Florida Intl
11h 20m
2 stops
SAN6:40 pmSan Diego
Oct 25
SAN8:30 amSan Diego
10h 05m
2 stops
RSW9:35 pmFort Myers SW Florida Intl
$344
Find similar
Southwest
Feb 2
RSW4:15 pmFort Myers SW Florida Intl
9h 50m
1 stop
SAN11:05 pmSan Diego
Feb 5
SAN7:30 amSan Diego
9h 05m
2 stops
RSW7:35 pmFort Myers SW Florida Intl
$356
Find similar
Southwest
Oct 14
RSW10:20 amFort Myers SW Florida Intl
11h 20m
2 stops
SAN6:40 pmSan Diego
Oct 21
SAN8:40 amSan Diego
10h 50m
2 stops
RSW10:30 pmFort Myers SW Florida Intl
$397
Find similar

Delta flights from Fort Myers to San Diego

Our best Delta deals on Fort Myers to San Diego flight tickets
Delta
Oct 14
RSW2:13 pmFort Myers SW Florida Intl
10h 40m
1 stop
SAN9:53 pmSan Diego
Oct 21
SAN7:25 amSan Diego
10h 47m
1 stop
RSW9:12 pmFort Myers SW Florida Intl
$317
Find similar
Delta
Oct 22
RSW8:00 amFort Myers SW Florida Intl
9h 32m
1 stop
SAN2:32 pmSan Diego
Oct 25
SAN10:20 pmSan Diego
10h 06m
1 stop
RSW11:26 amFort Myers SW Florida Intl
$327
Find similar
Delta
Oct 23
RSW6:41 pmFort Myers SW Florida Intl
7h 33m
1 stop
SAN11:14 pmSan Diego
Oct 26
SAN6:25 amSan Diego
7h 53m
1 stop
RSW5:18 pmFort Myers SW Florida Intl
$387
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Fort Myers to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Fort Myers to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersSan Diego

RSW - SAN

RSWSAN

Fort Myers SW Florida Intl

Sun 9/28

7:24 pm-11:53 pm

2 stops31h 29m

San Diego

Thu 10/2

6:35 am-6:51 pm

2 stops33h 16m

$279

Fort MyersSan Diego

RSW - SAN

RSWSAN

Fort Myers SW Florida Intl

Tue 3/3

9:55 am-7:34 pm

1 stop12h 39m

San Diego

Wed 3/4

10:25 am-10:54 pm

1 stop9h 29m

$295

Fort MyersSan Diego

RSW - SAN

RSWSAN

Fort Myers SW Florida Intl

Tue 10/14

2:13 pm-9:53 pm

1 stop10h 40m

San Diego

Tue 10/21

7:25 am-9:12 pm

1 stop10h 47m

$317

Fort MyersSan Diego

RSW - SAN

RSWSAN

Fort Myers SW Florida Intl

Wed 10/8

11:08 am-6:06 pm

1 stop9h 58m

San Diego

Sun 10/12

10:31 pm-9:08 am

1 stop7h 37m

$320

Fort MyersSan Diego

RSW - SAN

RSWSAN

Fort Myers SW Florida Intl

Tue 10/14

5:14 pm-11:41 pm

2 stops9h 27m

San Diego

Tue 10/21

9:01 am-7:55 pm

1 stop7h 54m

$322

Fort MyersSan Diego

RSW - SAN

RSWSAN

Fort Myers SW Florida Intl

Wed 10/22

8:00 am-2:32 pm

1 stop9h 32m

San Diego

Sat 10/25

10:20 pm-11:26 am

1 stop10h 06m

$327

Fort MyersSan Diego

RSW - SAN

RSWSAN

Fort Myers SW Florida Intl

Wed 10/22

3:45 pm-11:41 pm

2 stops10h 56m

San Diego

Sat 10/25

6:15 am-3:56 pm

1 stop6h 41m

$332

Fort MyersSan Diego

RSW - SAN

RSWSAN

Fort Myers SW Florida Intl

Wed 10/22

10:20 am-6:40 pm

2 stops11h 20m

San Diego

Sat 10/25

8:30 am-9:35 pm

2 stops10h 05m

$344

Fort MyersSan Diego

RSW - SAN

RSWSAN

Fort Myers SW Florida Intl

Mon 2/2

11:56 am-6:40 pm

1 stop9h 44m

San Diego

Thu 2/5

6:23 am-8:06 pm

1 stop10h 43m

$351

Fort MyersSan Diego

RSW - SAN

RSWSAN

Fort Myers SW Florida Intl

Mon 2/2

4:15 pm-11:05 pm

1 stop9h 50m

San Diego

Thu 2/5

7:30 am-7:35 pm

2 stops9h 05m

$356

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to San Diego from

How to get the cheapest flight ticket from Fort Myers to San Diego

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Diego?

If you are unable to visit San Diego during the month of May, then departing from Fort Myers during the month August is also very affordable. Most momondo users find prices during this month for around $416.

What is the cheapest day to depart on your flight to San Diego?

The cheapest day to depart from Fort Myers to San Diego is on a Wednesday. Travelers who choose to depart for San Diego on a Wednesday will often find tickets for as low as $417. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $619. These prices are subject to change though, so be sure to set up a Price Alert for flights to San Diego.

What is the cheapest time of day to depart on your flight to San Diego?

The cheapest time of day to fly to San Diego is in the evening when flights can be purchased for as low as $446. Flights in the afternoon are often more expensive with an average ticket price of $486.

How far in advance should I book a flight to San Diego?

You are more likely to see cheaper flights to San Diego from Fort Myers when booking weeks ahead of your departure date. In general, you can expect to find flights to San Diego for around $432 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Diego from Fort Myers for as low as $261 on momondo.

How have Fort Myers to San Diego flight prices changed over time?

As of September 2025, prices for Fort Myers to San Diego flights are approximately 16% cheaper when compared to flights at the same time last year.

When to book flights from Fort Myers to San Diego

Are you open to changing your travel dates? Check out the ideal times to fly from Fort Myers to San Diego according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Fort Myers to San Diego (RSW to SAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Fort Myers to San Diego

Direct flights

None
There are no direct flights from Fort Myers to San Diego. There are no popular flight routes from Fort Myers to San Diego.
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  • How far is Fort Myers SW Florida Intl to San Diego by plane?

    The straight-line distance from Fort Myers SW Florida Intl to San Diego is 2147.6 mi. Typically, this will take 7h 07m by plane in normal conditions.

  • When did momondo last update prices for flights from Fort Myers SW Florida Intl Airport to San Diego Airport?

    Prices for flights from Fort Myers SW Florida Intl Airport to San Diego Airport are updated daily.

  • How many operators does momondo search for flights from Fort Myers SW Florida Intl Airport to San Diego Airport?

  • How old do you have to be to fly from Fort Myers SW Florida Intl Airport to San Diego Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Fort Myers SW Florida Intl Airport to San Diego Airport.

  • What documentation or ID do you need to fly to San Diego Airport?

    The necessary travel and health documents for your San Diego Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Fort Myers to San Diego?

Best airlines flying from Fort Myers to San Diego

Compare and see reviews for airlines that fly from Fort Myers to San Diego with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $296Free CancellationRating
7.4
8,929 reviews
Search United Airlines flights
DeltaPriceFrom $296Free CancellationRating
7.9
7,954 reviews
Search Delta flights
American AirlinesPriceFrom $306Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
SouthwestPriceFrom $327Free CancellationRating
8.0
4,242 reviews
Search Southwest flights

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Coronado
Chula Vista
El Cajon
Julian
La Mesa
National City
Poway
Imperial Beach
San Ysidro
Borrego Springs
Lemon Grove
Alpine
Santee

Why use momondo?

Why should I use momondo to find a flight deal from Fort Myers to San Diego?

It is quick and easy to find Fort Myers to San Diego flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to San Diego that suits you.

Can I find flights from Fort Myers to San Diego with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Diego from Fort Myers with this policy.

How can momondo help me find flights from Fort Myers to San Diego?

Once all potential Fort Myers to San Diego flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Fort Myers to San Diego right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Fort Myers to San Diego flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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