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Cheap flights from Florence, South Carolina to Houston from $332

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Florence, South Carolina to Houston departing on 5/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Florence, South Carolina to Houston

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:20 am - 12:12 pm
FLO
-
HOU
7h 52m
2 stops
American Airlines Logo
6:01 am - 3:50 pm
HOU
-
FLO
8h 49m
2 stops
$369American Airlines
Sat, May 2 - Wed, May 6
American Airlines Logo
5:09 am - 9:24 am
FLO
-
IAH
5h 15m
1 stop
American Airlines Logo
9:04 am - 2:56 pm
IAH
-
FLO
4h 52m
1 stop
$383American Airlines
Thu, Sep 3 - Mon, Sep 7
American Airlines Logo
5:09 am - 9:24 am
FLO
-
IAH
5h 15m
1 stop
American Airlines Logo
10:26 am - 10:59 pm
IAH
-
FLO
11h 33m
2 stops
$388American Airlines
Thu, Sep 3 - Mon, Sep 7
American Airlines Logo
5:20 am - 9:13 am
FLO
-
IAH
4h 53m
1 stop
American Airlines Logo
6:02 am - 10:00 pm
IAH
-
FLO
14h 58m
1 stop
$485American Airlines
Wed, May 20 - Sun, May 24
American Airlines Logo
5:20 am - 3:51 pm
FLO
-
IAH
11h 31m
2 stops
American Airlines Logo
6:02 am - 10:00 pm
IAH
-
FLO
14h 58m
1 stop
$490American Airlines
Wed, May 20 - Sun, May 24
American Airlines Logo
6:15 am - 10:21 am
FLO
-
IAH
5h 06m
1 stop
American Airlines Logo
3:04 pm - 10:00 pm
IAH
-
FLO
5h 56m
1 stop
$506American Airlines
Tue, May 19 - Mon, May 25
American Airlines Logo
6:15 am - 10:21 am
FLO
-
IAH
5h 06m
1 stop
American Airlines Logo
5:00 am - 2:10 pm
IAH
-
FLO
8h 10m
2 stops
$511American Airlines
Tue, May 19 - Mon, May 25
American Airlines Logo
4:16 pm - 11:59 pm
FLO
-
IAH
8h 43m
2 stops
American Airlines Logo
9:02 am - 10:00 pm
IAH
-
FLO
11h 58m
2 stops
$513American Airlines
Wed, May 20 - Sun, May 24
American Airlines Logo
4:16 pm - 11:59 pm
FLO
-
IAH
8h 43m
2 stops
American Airlines Logo
5:00 am - 2:10 pm
IAH
-
FLO
8h 10m
2 stops
$516American Airlines
Wed, May 20 - Mon, May 25
American Airlines Logo
4:16 pm - 11:47 pm
FLO
-
HOU
8h 31m
2 stops
American Airlines Logo
6:01 am - 3:50 pm
HOU
-
FLO
8h 49m
2 stops
$541American Airlines
Wed, May 6 - Sun, May 10

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American Airlines flights from Florence, South Carolina to Houston

Our best American Airlines deals on Florence, South Carolina to Houston flight tickets
American Airlines
May 2
FLO5:20 amFlorence
7h 52m
2 stops
HOU12:12 pmHouston Hobby
May 6
HOU6:01 amHouston Hobby
8h 49m
2 stops
FLO3:50 pmFlorence
$369
American Airlines
Sep 3
FLO5:09 amFlorence
5h 15m
1 stop
IAH9:24 amHouston George Bush Intcntl
Sep 7
IAH9:04 amHouston George Bush Intcntl
4h 52m
1 stop
FLO2:56 pmFlorence
$383
American Airlines
Sep 3
FLO5:09 amFlorence
5h 15m
1 stop
IAH9:24 amHouston George Bush Intcntl
Sep 7
IAH10:26 amHouston George Bush Intcntl
11h 33m
2 stops
FLO10:59 pmFlorence
$388

momondo Fare Finder

 
Customize your flight search to find flights from Florence, South Carolina to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from Florence, South Carolina to Houston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Sat 5/2

5:20 am-12:12 pm

2 stops7h 52m

Houston Hobby

Wed 5/6

6:01 am-3:50 pm

2 stops8h 49m

$369
Quickest round-trip

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Thu 9/3

5:09 am-9:24 am

1 stop5h 15m

Houston George Bush Intcntl

Mon 9/7

9:04 am-2:56 pm

1 stop4h 52m

$383

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Thu 9/3

5:09 am-9:24 am

1 stop5h 15m

Houston George Bush Intcntl

Mon 9/7

10:26 am-10:59 pm

2 stops11h 33m

$388

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Wed 5/20

5:20 am-9:13 am

1 stop4h 53m

Houston George Bush Intcntl

Sun 5/24

6:02 am-10:00 pm

1 stop14h 58m

$485

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Wed 5/20

5:20 am-3:51 pm

2 stops11h 31m

Houston George Bush Intcntl

Sun 5/24

6:02 am-10:00 pm

1 stop14h 58m

$490

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Tue 5/19

6:15 am-10:21 am

1 stop5h 06m

Houston George Bush Intcntl

Mon 5/25

3:04 pm-10:00 pm

1 stop5h 56m

$506

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Tue 5/19

6:15 am-10:21 am

1 stop5h 06m

Houston George Bush Intcntl

Mon 5/25

5:00 am-2:10 pm

2 stops8h 10m

$511

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Wed 5/20

4:16 pm-11:59 pm

2 stops8h 43m

Houston George Bush Intcntl

Sun 5/24

9:02 am-10:00 pm

2 stops11h 58m

$513

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Wed 5/20

4:16 pm-11:59 pm

2 stops8h 43m

Houston George Bush Intcntl

Mon 5/25

5:00 am-2:10 pm

2 stops8h 10m

$516

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Wed 5/6

4:16 pm-11:47 pm

2 stops8h 31m

Houston Hobby

Sun 5/10

6:01 am-3:50 pm

2 stops8h 49m

$541

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Houston from

How to get the cheapest flight ticket from Florence, South Carolina to Houston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Florence to Houston?

American Airlines is the most popular carrier operating from Florence to Houston

What airlines fly to Houston?

American Airlines, Frontier and United Airlines are the top three most popular airlines that fly to Houston from Florence, South Carolina according to our data. American Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Houston. Keep in mind that there are 7 different airlines that fly to Houston on a routine basis, so you have a few additional options to choose from.

Cheap Florence, South Carolina to Houston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to Houston

Fastest flight time

4h 53m

Direct flights

None
The fastest flight from Florence, South Carolina to Houston takes 4h 53m
There are no direct flights from Florence, South Carolina to Houston. There are no popular flight routes from Florence, South Carolina to Houston.
Search flight deals

Frequently asked questions about flying from Florence, South Carolina to Houston

  • How far is Florence to Houston by plane?

    A flight from Florence to Houston will travel around 962.7 mi. In terms of flight time, this usually takes a little over 4h 53m.

  • When did momondo last update prices for flights from Florence Airport to Houston?

    Prices for flights from Florence Airport to Houston were last updated today.

  • How many operators does momondo search for flights from Florence Airport to Houston?

  • How old do you have to be to fly from Florence Airport to Houston?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Florence Airport to Houston.

  • What documentation or ID do you need to fly to Houston?

    The required travel and health documents for your Houston trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Houston. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Florence, South Carolina to Houston

Compare and see reviews for airlines that fly from Florence, South Carolina to Houston with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $254Free CancellationRating
7.1
11,647 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Florence to Houston?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Florence to Houston. momondo saves you time and could save you money on your trip.

Can I find flights from Florence to Houston with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Houston from Florence with this policy.

How can momondo help me find flights from Florence to Houston?

Once all potential Florence to Houston flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Florence to Houston right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Florence to Houston now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Houston and let you know when they change.

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