What airlines fly to Detroit?

American Airlines, Delta and Frontier are the top three most popular airlines that fly to Detroit from Florence, South Carolina according to our data. American Airlines is the first choice among our users, with 51% of people opting to fly with this airline when traveling to Detroit. Keep in mind that there are 6 different airlines that fly to Detroit on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Florence to Detroit?

American Airlines is the most popular carrier operating from Florence to Detroit

When did momondo last update prices for flights from Florence Airport to Detroit?

Prices for flights from Florence Airport to Detroit refresh daily.

How old do you have to be to fly from Florence Airport to Detroit?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Florence Airport to Detroit.

What documentation or ID do you need to fly to Detroit?

The required travel and health documents for your Detroit trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Detroit. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$396 Cheap Flights from Florence, South Carolina to Detroit in 2026/27

Find the cheapest flights from Florence, South Carolina to Detroit

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:09 am - 9:21 amFLO Florence-DTW Detroit Metropolitan Wayne County

4h 12m1 stop Charlotte Douglas

4:59 pm - 11:57 pmDTW Detroit Metropolitan Wayne County-FLO Florence

6h 58m1 stop Charlotte Douglas

$585American Airlines

Fri, Oct 16 - Fri, Oct 23

1:43 pm - 5:30 pmFLO Florence-DTW Detroit Metropolitan Wayne County

3h 47m1 stop Charlotte Douglas

7:15 am - 2:10 pmDTW Detroit Metropolitan Wayne County-FLO Florence

6h 55m1 stop Charlotte Douglas

$669American Airlines

Thu, Oct 1 - Sun, Oct 4

2:34 pm - 7:15 pmFLO Florence-DTW Detroit Metropolitan Wayne County

4h 41m1 stop Charlotte Douglas

1:35 pm - 11:57 pmDTW Detroit Metropolitan Wayne County-FLO Florence

10h 22m2 stops Chicago O'Hare Intl Charlotte Douglas

$674American Airlines

Fri, Oct 16 - Fri, Oct 23

2:35 pm - 7:07 pmFLO Florence-DTW Detroit Metropolitan Wayne County

4h 32m1 stop Charlotte Douglas

10:20 am - 11:57 pmDTW Detroit Metropolitan Wayne County-FLO Florence

13h 37m2 stops Chicago O'Hare Intl Charlotte Douglas

$712American Airlines

Sun, Dec 20 - Mon, Jan 4

1:43 pm - 10:23 pmFLO Florence-DTW Detroit Metropolitan Wayne County

8h 40m2 stops Charlotte Douglas New York LaGuardia

7:15 am - 2:10 pmDTW Detroit Metropolitan Wayne County-FLO Florence

6h 55m1 stop Charlotte Douglas

$786American Airlines

Thu, Oct 1 - Sun, Oct 4

5:09 am - 4:09 pmFLO Florence-DTW Detroit Metropolitan Wayne County

11h 00m2 stops Charlotte Douglas Chicago O'Hare Intl

1:35 pm - 11:57 pmDTW Detroit Metropolitan Wayne County-FLO Florence

10h 22m2 stops Chicago O'Hare Intl Charlotte Douglas

$813American Airlines

Fri, Oct 16 - Fri, Oct 23

5:09 am - 4:04 pmFLO Florence-DTW Detroit Metropolitan Wayne County

10h 55m2 stops Charlotte Douglas Chicago O'Hare Intl

10:20 am - 11:57 pmDTW Detroit Metropolitan Wayne County-FLO Florence

13h 37m2 stops Chicago O'Hare Intl Charlotte Douglas

$839American Airlines

Mon, Dec 21 - Mon, Jan 4

5:09 am - 3:41 pmFLO Florence-DTW Detroit Metropolitan Wayne County

10h 32m2 stops Charlotte Douglas Philadelphia

11:04 am - 11:57 pmDTW Detroit Metropolitan Wayne County-FLO Florence

12h 53m2 stops Philadelphia Charlotte Douglas

$867American Airlines

Sun, Dec 20 - Mon, Jan 4

1:43 pm - 10:23 pmFLO Florence-DTW Detroit Metropolitan Wayne County

8h 40m2 stops Charlotte Douglas New York LaGuardia

6:00 am - 2:10 pmDTW Detroit Metropolitan Wayne County-FLO Florence

8h 10m2 stops Philadelphia Charlotte Douglas

$903American Airlines

Thu, Oct 1 - Sun, Oct 4

6:24 am - 10:15 amFLO Florence-DTW Detroit Metropolitan Wayne County

3h 51m1 stop Charlotte Douglas

2:13 pm - 10:58 pmDTW Detroit Metropolitan Wayne County-FLO Florence

8h 45m2 stops New York LaGuardia Charlotte Douglas

$1,025American Airlines

Mon, Sep 28 - Fri, Oct 2

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American Airlines flights from Florence, South Carolina to Detroit

Our best American Airlines deals on Florence, South Carolina to Detroit flight tickets

American Airlines

Oct 16

FLO5:09 amFlorence

4h 12m

1 stop

DTW9:21 amDetroit Metropolitan Wayne County

Oct 23

DTW4:59 pmDetroit Metropolitan Wayne County

6h 58m

1 stop

FLO11:57 pmFlorence

$585

American Airlines

Oct 1

FLO1:43 pmFlorence

3h 47m

1 stop

DTW5:30 pmDetroit Metropolitan Wayne County

Oct 4

DTW7:15 amDetroit Metropolitan Wayne County

6h 55m

1 stop

FLO2:10 pmFlorence

$669

American Airlines

Oct 16

FLO2:34 pmFlorence

4h 41m

1 stop

DTW7:15 pmDetroit Metropolitan Wayne County

Oct 23

DTW1:35 pmDetroit Metropolitan Wayne County

10h 22m

2 stops

FLO11:57 pmFlorence

$674

momondo Fare Finder

Use the filters below to find and compare flights from Florence, South Carolina to Detroit that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Fri 10/16

5:09 am-9:21 am

1 stop4h 12m

Detroit Metropolitan Wayne County

Fri 10/23

4:59 pm-11:57 pm

1 stop6h 58m

$585

Quickest round-trip

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Thu 10/1

1:43 pm-5:30 pm

1 stop3h 47m

Detroit Metropolitan Wayne County

Sun 10/4

7:15 am-2:10 pm

1 stop6h 55m

$669

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Fri 10/16

2:34 pm-7:15 pm

1 stop4h 41m

Detroit Metropolitan Wayne County

Fri 10/23

1:35 pm-11:57 pm

2 stops10h 22m

$674

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Sun 12/20

2:35 pm-7:07 pm

1 stop4h 32m

Detroit Metropolitan Wayne County

Mon 1/4

10:20 am-11:57 pm

2 stops13h 37m

$712

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Thu 10/1

1:43 pm-10:23 pm

2 stops8h 40m

Detroit Metropolitan Wayne County

Sun 10/4

7:15 am-2:10 pm

1 stop6h 55m

$786

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Fri 10/16

5:09 am-4:09 pm

2 stops11h 00m

Detroit Metropolitan Wayne County

Fri 10/23

1:35 pm-11:57 pm

2 stops10h 22m

$813

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Mon 12/21

5:09 am-4:04 pm

2 stops10h 55m

Detroit Metropolitan Wayne County

Mon 1/4

10:20 am-11:57 pm

2 stops13h 37m

$839

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Sun 12/20

5:09 am-3:41 pm

2 stops10h 32m

Detroit Metropolitan Wayne County

Mon 1/4

11:04 am-11:57 pm

2 stops12h 53m

$867

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Thu 10/1

1:43 pm-10:23 pm

2 stops8h 40m

Detroit Metropolitan Wayne County

Sun 10/4

6:00 am-2:10 pm

2 stops8h 10m

$903

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Mon 9/28

6:24 am-10:15 am

1 stop3h 51m

Detroit Metropolitan Wayne County

Fri 10/2

2:13 pm-10:58 pm

2 stops8h 45m

$1,025

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first

How to get the cheapest flight ticket from Florence, South Carolina to Detroit

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Florence, South Carolina to Detroit flights?

You could potentially save up to 12% on your flight if you consider stops on a Florence, South Carolina to Detroit flight.

When to book flights from Florence, South Carolina to Detroit

Are you open to changing your travel dates? Check out the ideal times to fly from Florence, South Carolina to Detroit according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Florence, South Carolina to Detroit (FLO to DTT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to Detroit

Best Price Found	$396
Fastest flight time	4h 12m
Direct flights	None

The best one-way flight to Detroit from Florence, South Carolina in the past 72 hours is $396. The best round-trip flight deal from Florence, South Carolina to Detroit found on momondo in the last 72 hours is $585.

The fastest flight from Florence, South Carolina to Detroit takes 4h 12m

There are no direct flights from Florence, South Carolina to Detroit. There are no popular flight routes from Florence, South Carolina to Detroit.

Search flight deals

Frequently asked questions about flying from Florence, South Carolina to Detroit

How far is Florence to Detroit by plane?
The distance between Florence and Detroit is about 589.7 mi. A reasonable flight in good conditions will take 4h 12m.
When did momondo last update prices for flights from Florence Airport to Detroit?
Prices for flights from Florence Airport to Detroit refresh daily.
How old do you have to be to fly from Florence Airport to Detroit?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Florence Airport to Detroit.
What documentation or ID do you need to fly to Detroit?
The required travel and health documents for your Detroit trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Detroit. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Roseville

Port Huron

Why use momondo?

Why should I use momondo to find a flight deal from Florence to Detroit?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Florence to Detroit for you.

Can I find flights from Florence to Detroit with flexible booking policies on momondo?

Flights from Florence to Detroit with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Florence to Detroit?

momondo helps you find the best flight between Florence and Detroit by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Florence to Detroit right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Detroit from Florence. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.