What airlines fly to Detroit Metropolitan Wayne County Airport?

American Airlines, Delta and Frontier are the top three most popular airlines that fly to Detroit Metropolitan Wayne County Airport from Florence, South Carolina according to our data. American Airlines is the first choice among our users, with 51% of people opting to fly with this airline when traveling to Detroit Metropolitan Wayne County Airport. Keep in mind that there are 6 different airlines that fly to Detroit Metropolitan Wayne County Airport on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Florence Airport to Detroit Metropolitan Wayne County Airport?

Prices for flights from Florence Airport to Detroit Metropolitan Wayne County Airport refresh daily.

How old do you have to be to fly from Florence Airport to Detroit Metropolitan Wayne County Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Florence Airport to Detroit Metropolitan Wayne County Airport.

What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

The required travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Detroit Metropolitan Wayne County Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$585 Cheap Flights from Florence, South Carolina to Detroit Metropolitan Wayne County Airport in 2026/27

Find the cheapest flights from Florence, South Carolina to Detroit

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:09 am - 9:21 amFLO Florence-DTW Detroit Metropolitan Wayne County

4h 12m1 stop Charlotte Douglas

4:59 pm - 11:57 pmDTW Detroit Metropolitan Wayne County-FLO Florence

6h 58m1 stop Charlotte Douglas

$585American Airlines

Fri, Oct 16 - Fri, Oct 23

2:34 pm - 7:15 pmFLO Florence-DTW Detroit Metropolitan Wayne County

4h 41m1 stop Charlotte Douglas

1:35 pm - 11:57 pmDTW Detroit Metropolitan Wayne County-FLO Florence

10h 22m2 stops Chicago O'Hare Intl Charlotte Douglas

$674American Airlines

Fri, Oct 16 - Fri, Oct 23

2:35 pm - 7:07 pmFLO Florence-DTW Detroit Metropolitan Wayne County

4h 32m1 stop Charlotte Douglas

10:20 am - 11:57 pmDTW Detroit Metropolitan Wayne County-FLO Florence

13h 37m2 stops Chicago O'Hare Intl Charlotte Douglas

$712American Airlines

Sun, Dec 20 - Mon, Jan 4

5:09 am - 4:09 pmFLO Florence-DTW Detroit Metropolitan Wayne County

11h 00m2 stops Charlotte Douglas Chicago O'Hare Intl

1:35 pm - 11:57 pmDTW Detroit Metropolitan Wayne County-FLO Florence

10h 22m2 stops Chicago O'Hare Intl Charlotte Douglas

$813American Airlines

Fri, Oct 16 - Fri, Oct 23

5:09 am - 4:04 pmFLO Florence-DTW Detroit Metropolitan Wayne County

10h 55m2 stops Charlotte Douglas Chicago O'Hare Intl

10:20 am - 11:57 pmDTW Detroit Metropolitan Wayne County-FLO Florence

13h 37m2 stops Chicago O'Hare Intl Charlotte Douglas

$839American Airlines

Mon, Dec 21 - Mon, Jan 4

5:09 am - 3:41 pmFLO Florence-DTW Detroit Metropolitan Wayne County

10h 32m2 stops Charlotte Douglas Philadelphia

11:04 am - 11:57 pmDTW Detroit Metropolitan Wayne County-FLO Florence

12h 53m2 stops Philadelphia Charlotte Douglas

$867American Airlines

Sun, Dec 20 - Mon, Jan 4

Cheap last minute flights

Enter your travel dates to find the best prices.

6:24 am - 10:15 amFLO Florence-DTW Detroit Metropolitan Wayne County

3h 51m1 stop Charlotte Douglas

7:30 am - 1:18 pmDTW Detroit Metropolitan Wayne County-FLO Florence

5h 48m1 stop Charlotte Douglas

$629American Airlines

Tue, Sep 22 - Sat, Sep 26

1:43 pm - 5:30 pmFLO Florence-DTW Detroit Metropolitan Wayne County

3h 47m1 stop Charlotte Douglas

7:30 am - 1:18 pmDTW Detroit Metropolitan Wayne County-FLO Florence

5h 48m1 stop Charlotte Douglas

$649American Airlines

Mon, Sep 21 - Wed, Sep 30

1:43 pm - 5:30 pmFLO Florence-DTW Detroit Metropolitan Wayne County

3h 47m1 stop Charlotte Douglas

7:15 am - 2:10 pmDTW Detroit Metropolitan Wayne County-FLO Florence

6h 55m1 stop Charlotte Douglas

$669American Airlines

Mon, Sep 21 - Sun, Sep 27

6:24 am - 10:15 amFLO Florence-DTW Detroit Metropolitan Wayne County

3h 51m1 stop Charlotte Douglas

12:55 pm - 10:58 pmDTW Detroit Metropolitan Wayne County-FLO Florence

10h 03m2 stops Philadelphia Charlotte Douglas

$677American Airlines

Tue, Sep 22 - Tue, Sep 29

1:43 pm - 5:30 pmFLO Florence-DTW Detroit Metropolitan Wayne County

3h 47m1 stop Charlotte Douglas

12:55 pm - 10:58 pmDTW Detroit Metropolitan Wayne County-FLO Florence

10h 03m2 stops Philadelphia Charlotte Douglas

$697American Airlines

Mon, Sep 21 - Wed, Sep 30

6:24 am - 10:15 amFLO Florence-DTW Detroit Metropolitan Wayne County

3h 51m1 stop Charlotte Douglas

7:30 am - 1:18 pmDTW Detroit Metropolitan Wayne County-FLO Florence

5h 48m1 stop Charlotte Douglas

$708American Airlines

Tue, Sep 22 - Tue, Sep 29

1:43 pm - 11:43 pmFLO Florence-DTW Detroit Metropolitan Wayne County

10h 00m2 stops Charlotte Douglas Dallas/Fort Worth

11:27 am - 10:58 pmDTW Detroit Metropolitan Wayne County-FLO Florence

11h 31m2 stops Philadelphia Charlotte Douglas

$725American Airlines

Tue, Sep 22 - Wed, Sep 30

1:43 pm - 5:30 pmFLO Florence-DTW Detroit Metropolitan Wayne County

3h 47m1 stop Charlotte Douglas

7:30 am - 1:18 pmDTW Detroit Metropolitan Wayne County-FLO Florence

5h 48m1 stop Charlotte Douglas

$728American Airlines

Mon, Sep 21 - Tue, Sep 29

1:43 pm - 5:30 pmFLO Florence-DTW Detroit Metropolitan Wayne County

3h 47m1 stop Charlotte Douglas

7:30 am - 1:18 pmDTW Detroit Metropolitan Wayne County-FLO Florence

5h 48m1 stop Charlotte Douglas

$772American Airlines

Thu, Sep 24 - Wed, Sep 30

6:24 am - 10:15 amFLO Florence-DTW Detroit Metropolitan Wayne County

3h 51m1 stop Charlotte Douglas

12:56 pm - 10:58 pmDTW Detroit Metropolitan Wayne County-FLO Florence

10h 02m2 stops Chicago O'Hare Intl Charlotte Douglas

$777American Airlines

Tue, Sep 22 - Fri, Oct 2

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American Airlines flights from Florence, South Carolina to Detroit Metropolitan Wayne County Airport

Our best American Airlines deals on Florence, South Carolina to Detroit Metropolitan Wayne County Airport flight tickets

American Airlines

Oct 16

FLO5:09 amFlorence

4h 12m

1 stop

DTW9:21 amDetroit Metropolitan Wayne County

Oct 23

DTW4:59 pmDetroit Metropolitan Wayne County

6h 58m

1 stop

FLO11:57 pmFlorence

$585

American Airlines

Sep 22

FLO6:24 amFlorence

3h 51m

1 stop

DTW10:15 amDetroit Metropolitan Wayne County

Sep 26

DTW7:30 amDetroit Metropolitan Wayne County

5h 48m

1 stop

FLO1:18 pmFlorence

$629

American Airlines

Sep 21

FLO1:43 pmFlorence

3h 47m

1 stop

DTW5:30 pmDetroit Metropolitan Wayne County

Sep 30

DTW7:30 amDetroit Metropolitan Wayne County

5h 48m

1 stop

FLO1:18 pmFlorence

$649

momondo Fare Finder

Use the filters below to find and compare flights from Florence, South Carolina to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Fri 10/16

5:09 am-9:21 am

1 stop4h 12m

Detroit Metropolitan Wayne County

Fri 10/23

4:59 pm-11:57 pm

1 stop6h 58m

$585

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Fri 10/16

2:34 pm-7:15 pm

1 stop4h 41m

Detroit Metropolitan Wayne County

Fri 10/23

1:35 pm-11:57 pm

2 stops10h 22m

$674

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Sun 12/20

2:35 pm-7:07 pm

1 stop4h 32m

Detroit Metropolitan Wayne County

Mon 1/4

10:20 am-11:57 pm

2 stops13h 37m

$712

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Fri 10/16

5:09 am-4:09 pm

2 stops11h 00m

Detroit Metropolitan Wayne County

Fri 10/23

1:35 pm-11:57 pm

2 stops10h 22m

$813

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Mon 12/21

5:09 am-4:04 pm

2 stops10h 55m

Detroit Metropolitan Wayne County

Mon 1/4

10:20 am-11:57 pm

2 stops13h 37m

$839

FlorenceDetroit

FLO Florence - DTW Detroit Metropolitan Wayne County

FLODTW

Florence

Sun 12/20

5:09 am-3:41 pm

2 stops10h 32m

Detroit Metropolitan Wayne County

Mon 1/4

11:04 am-11:57 pm

2 stops12h 53m

$867

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Florence, South Carolina to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Florence, South Carolina to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 12% on your flight if you consider stops on a Florence, South Carolina to Detroit Metropolitan Wayne County Airport flight.

When to book flights from Florence, South Carolina to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Florence, South Carolina to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Florence, South Carolina to Detroit Metropolitan Wayne County Airport (FLO to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to Detroit Metropolitan Wayne County Airport

Best Price Found	$585
Fastest flight time	3h 47m
Direct flights	None

The best flight deal from Florence, South Carolina to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $585

The fastest flight from Florence, South Carolina to Detroit Metropolitan Wayne County Airport takes 3h 47m

There are no direct flights from Florence, South Carolina to Detroit Metropolitan Wayne County Airport. There are no popular flight routes from Florence, South Carolina to Detroit Metropolitan Wayne County Airport.

Search flight deals

Frequently asked questions about flying from Florence, South Carolina to Detroit Metropolitan Wayne County Airport

How far is Florence to Detroit Metropolitan Wayne County by plane?
Florence and Detroit Metropolitan Wayne County are 587.3 mi apart from one another. In terms of flight time, this usually takes a little over 3h 47m.
When did momondo last update prices for flights from Florence Airport to Detroit Metropolitan Wayne County Airport?
Prices for flights from Florence Airport to Detroit Metropolitan Wayne County Airport refresh daily.
How old do you have to be to fly from Florence Airport to Detroit Metropolitan Wayne County Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Florence Airport to Detroit Metropolitan Wayne County Airport.
What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?
The required travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Detroit Metropolitan Wayne County Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

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Pontiac

Ypsilanti

Farmington Hills

Howell

Why use momondo?

Why should I use momondo to find a flight deal from Florence to Detroit?

Finding the right flight to Detroit from Florence is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Detroit quick and easy, saving you time and money.

Can I find flights from Florence to Detroit with flexible booking policies on momondo?

Yes. All flights to Detroit from Florence on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Florence to Detroit?

Once you have performed a search for Florence to Detroit flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Florence to Detroit right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Florence to Detroit flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.