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Cheap flights from Detroit to Greenville from $449

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit to Greenville departing on 9/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Detroit to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:15 pm - 4:49 pm
DTW
-
PGV
4h 34m
1 stop
American Airlines Logo
12:21 pm - 5:22 pm
PGV
-
DTW
5h 01m
1 stop
$491American Airlines
Tue, Sep 1 - Tue, Sep 8
American Airlines Logo
6:00 am - 11:56 am
DTW
-
PGV
5h 56m
1 stop
American Airlines Logo
6:10 am - 11:35 am
PGV
-
DTW
5h 25m
1 stop
$558American Airlines
Tue, Sep 1 - Mon, Sep 7
American Airlines Logo
7:30 am - 11:40 am
DTW
-
PGV
4h 10m
1 stop
American Airlines Logo
11:01 am - 3:51 pm
PGV
-
DTW
4h 50m
1 stop
$565American Airlines
Thu, Sep 24 - Sun, Sep 27
American Airlines Logo
6:40 am - 4:49 pm
DTW
-
PGV
10h 09m
2 stops
American Airlines Logo
5:15 pm - 10:30 pm
PGV
-
DTW
5h 15m
1 stop
$609American Airlines
Tue, Sep 1 - Tue, Sep 8
American Airlines Logo
6:00 am - 11:56 am
DTW
-
PGV
5h 56m
1 stop
American Airlines Logo
6:10 am - 11:35 am
PGV
-
DTW
5h 25m
1 stop
$629American Airlines
Fri, Aug 14 - Tue, Aug 18
American Airlines Logo
1:01 pm - 10:59 pm
DTW
-
PGV
9h 58m
2 stops
American Airlines Logo
12:21 pm - 5:22 pm
PGV
-
DTW
5h 01m
1 stop
$673American Airlines
Tue, Sep 1 - Mon, Sep 7
American Airlines Logo
6:43 pm - 10:59 pm
DTW
-
PGV
4h 16m
1 stop
American Airlines Logo
12:21 pm - 9:38 pm
PGV
-
DTW
9h 17m
2 stops
$677American Airlines
Fri, Aug 14 - Tue, Aug 18
American Airlines Logo
9:39 am - 4:49 pm
DTW
-
PGV
7h 10m
2 stops
American Airlines Logo
6:10 am - 3:00 pm
PGV
-
DTW
8h 50m
2 stops
$705American Airlines
Tue, Sep 1 - Tue, Sep 8
American Airlines Logo
6:36 am - 4:52 pm
DTW
-
PGV
10h 16m
2 stops
American Airlines Logo
6:14 pm - 12:26 am
PGV
-
DTW
6h 12m
1 stop
$766American Airlines
Thu, Sep 24 - Sun, Sep 27
American Airlines Logo
7:30 am - 11:40 am
DTW
-
PGV
4h 10m
1 stop
American Airlines Logo
5:09 am - 3:31 pm
PGV
-
DTW
10h 22m
2 stops
$777American Airlines
Thu, Sep 24 - Sun, Sep 27

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American Airlines flights from Detroit to Greenville, North Carolina

Our best American Airlines deals on Detroit to Greenville, North Carolina flight tickets
American Airlines
Sep 1
DTW12:15 pmDetroit Metropolitan Wayne County
4h 34m
1 stop
PGV4:49 pmPitt-Greenville
Sep 8
PGV12:21 pmPitt-Greenville
5h 01m
1 stop
DTW5:22 pmDetroit Metropolitan Wayne County
$491
American Airlines
Sep 1
DTW6:00 amDetroit Metropolitan Wayne County
5h 56m
1 stop
PGV11:56 amPitt-Greenville
Sep 7
PGV6:10 amPitt-Greenville
5h 25m
1 stop
DTW11:35 amDetroit Metropolitan Wayne County
$558
American Airlines
Sep 24
DTW7:30 amDetroit Metropolitan Wayne County
4h 10m
1 stop
PGV11:40 amPitt-Greenville
Sep 27
PGV11:01 amPitt-Greenville
4h 50m
1 stop
DTW3:51 pmDetroit Metropolitan Wayne County
$565

momondo Fare Finder

 
Customize your flight search to find flights from Detroit to Greenville, North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from Detroit to Greenville, North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitGreenville

DTW - PGV

DTWPGV

Detroit Metropolitan Wayne County

Tue 9/1

12:15 pm-4:49 pm

1 stop4h 34m

Pitt-Greenville

Tue 9/8

12:21 pm-5:22 pm

1 stop5h 01m

$491

DetroitGreenville

DTW - PGV

DTWPGV

Detroit Metropolitan Wayne County

Tue 9/1

6:00 am-11:56 am

1 stop5h 56m

Pitt-Greenville

Mon 9/7

6:10 am-11:35 am

1 stop5h 25m

$558
Quickest round-trip

DetroitGreenville

DTW - PGV

DTWPGV

Detroit Metropolitan Wayne County

Thu 9/24

7:30 am-11:40 am

1 stop4h 10m

Pitt-Greenville

Sun 9/27

11:01 am-3:51 pm

1 stop4h 50m

$565

DetroitGreenville

DTW - PGV

DTWPGV

Detroit Metropolitan Wayne County

Tue 9/1

6:40 am-4:49 pm

2 stops10h 09m

Pitt-Greenville

Tue 9/8

5:15 pm-10:30 pm

1 stop5h 15m

$609

DetroitGreenville

DTW - PGV

DTWPGV

Detroit Metropolitan Wayne County

Fri 8/14

6:00 am-11:56 am

1 stop5h 56m

Pitt-Greenville

Tue 8/18

6:10 am-11:35 am

1 stop5h 25m

$629

DetroitGreenville

DTW - PGV

DTWPGV

Detroit Metropolitan Wayne County

Tue 9/1

1:01 pm-10:59 pm

2 stops9h 58m

Pitt-Greenville

Mon 9/7

12:21 pm-5:22 pm

1 stop5h 01m

$673

DetroitGreenville

DTW - PGV

DTWPGV

Detroit Metropolitan Wayne County

Fri 8/14

6:43 pm-10:59 pm

1 stop4h 16m

Pitt-Greenville

Tue 8/18

12:21 pm-9:38 pm

2 stops9h 17m

$677

DetroitGreenville

DTW - PGV

DTWPGV

Detroit Metropolitan Wayne County

Tue 9/1

9:39 am-4:49 pm

2 stops7h 10m

Pitt-Greenville

Tue 9/8

6:10 am-3:00 pm

2 stops8h 50m

$705

DetroitGreenville

DTW - PGV

DTWPGV

Detroit Metropolitan Wayne County

Thu 9/24

6:36 am-4:52 pm

2 stops10h 16m

Pitt-Greenville

Sun 9/27

6:14 pm-12:26 am

1 stop6h 12m

$766

DetroitGreenville

DTW - PGV

DTWPGV

Detroit Metropolitan Wayne County

Thu 9/24

7:30 am-11:40 am

1 stop4h 10m

Pitt-Greenville

Sun 9/27

5:09 am-3:31 pm

2 stops10h 22m

$777

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Detroit to Greenville, North Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Detroit to Pitt-Greenville?

American Airlines is the most popular carrier operating from Detroit to Pitt-Greenville

What airlines fly to Greenville, North Carolina?

Delta, Frontier and American Airlines are the top three most popular airlines that fly to Greenville, North Carolina from Detroit according to our data. Delta is the first choice among our users, with 51% of people opting to fly with this airline when traveling to Greenville, North Carolina. Keep in mind that there are 5 different airlines that fly to Greenville, North Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Detroit to Greenville, North Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit to Greenville, North Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit to Greenville, North Carolina (DTT to PGV) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit to Greenville, North Carolina

Fastest flight time

5h 56m

Direct flights

None
The fastest flight from Detroit to Greenville, North Carolina takes 5h 56m
There are no direct flights from Detroit to Greenville, North Carolina. There are no popular flight routes from Detroit to Greenville, North Carolina.
Search flight deals

Frequently asked questions about flying from Detroit to Greenville, North Carolina

  • How far is Detroit to Pitt-Greenville by plane?

    The distance between Detroit and Pitt-Greenville is about 555.4 mi. 5h 56m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Detroit to Pitt-Greenville Airport?

    Prices for flights from Detroit to Pitt-Greenville Airport are updated daily.

  • How old do you have to be to fly from Detroit to Pitt-Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit to Pitt-Greenville Airport.

  • What documentation or ID do you need to fly to Pitt-Greenville Airport?

    The travel and health documents you'll need for your trip to Pitt-Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Pitt-Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Kinston
Washington
Williamston
Plymouth
Windsor

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Greenville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Detroit to Greenville for you.

Can I find flights from Detroit to Greenville with flexible booking policies on momondo?

Yes. All flights to Greenville from Detroit on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Detroit to Greenville?

momondo helps you find the best flight between Detroit and Greenville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Detroit to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Detroit are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Greenville, North Carolina trip

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