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Cheap flights from Des Moines to San Luis Obispo from $289

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Luis Obispo departing on 10/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to San Luis Obispo

Cheap round-trip flights

American Airlines Logo
2:28 pm - 6:27 pmDSM-SBP
5h 59m1 stop
American Airlines Logo
12:27 pm - 10:56 pmSBP-DSM
8h 29m1 stop
$289American Airlines
Find Deal
Sat, Oct 11 - Fri, Oct 17
American Airlines Logo
5:00 am - 11:37 amDSM-SBP
8h 37m1 stop
American Airlines Logo
7:16 pm - 8:22 amSBP-DSM
11h 06m2 stops
$294American Airlines
Find Deal
Sat, Oct 11 - Fri, Oct 17
American Airlines Logo
5:00 am - 11:57 amDSM-SBP
8h 57m2 stops
American Airlines Logo
6:05 am - 4:17 pmSBP-DSM
8h 12m2 stops
$299American Airlines
Find Deal
Sat, Oct 25 - Tue, Oct 28
American Airlines Logo
5:00 am - 11:57 amDSM-SBP
8h 57m2 stops
American Airlines Logo
7:16 pm - 8:22 amSBP-DSM
11h 06m2 stops
$410American Airlines
Find Deal
Sat, Oct 11 - Fri, Oct 17
American Airlines Logo
5:00 am - 9:06 amDSM-SBP
6h 06m1 stop
American Airlines Logo
4:18 pm - 11:59 pmSBP-DSM
5h 41m1 stop
$423American Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
American Airlines Logo
5:00 am - 11:39 amDSM-SBP
8h 39m1 stop
American Airlines Logo
6:00 am - 4:40 pmSBP-DSM
8h 40m2 stops
$428American Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
American Airlines Logo
8:50 am - 6:29 pmDSM-SBP
11h 39m2 stops
American Airlines Logo
6:00 am - 5:57 pmSBP-DSM
9h 57m2 stops
$433American Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
American Airlines Logo
5:00 am - 4:06 pmDSM-SBP
13h 06m2 stops
American Airlines Logo
7:16 pm - 8:22 amSBP-DSM
11h 06m2 stops
$436American Airlines
Find Deal
Sat, Oct 11 - Fri, Oct 17
United Airlines Logo
8:00 am - 10:15 pmDSM-SBP
16h 15m3 stops
United Airlines Logo
6:25 pm - 8:45 pmSBP-DSM
24h 20m2 stops
$453United Airlines
Find Deal
Sat, Oct 25 - Tue, Oct 28
United Airlines Logo
8:00 am - 10:14 pmDSM-SBP
16h 14m3 stops
United Airlines Logo
6:22 pm - 10:32 amSBP-DSM
14h 10m2 stops
$524United Airlines
Find Deal
Sat, Oct 11 - Fri, Oct 17

American Airlines flights from Des Moines to San Luis Obispo

Our best American Airlines deals on Des Moines to San Luis Obispo flight tickets
American Airlines
Oct 11
DSM2:28 pmDes Moines
5h 59m
1 stop
SBP6:27 pmSan Luis Obispo County
Oct 17
SBP12:27 pmSan Luis Obispo County
8h 29m
1 stop
DSM10:56 pmDes Moines
$289
Find similar
American Airlines
Oct 11
DSM5:00 amDes Moines
8h 37m
1 stop
SBP11:37 amSan Luis Obispo County
Oct 17
SBP7:16 pmSan Luis Obispo County
11h 06m
2 stops
DSM8:22 amDes Moines
$294
Find similar
American Airlines
Oct 25
DSM5:00 amDes Moines
8h 57m
2 stops
SBP11:57 amSan Luis Obispo County
Oct 28
SBP6:05 amSan Luis Obispo County
8h 12m
2 stops
DSM4:17 pmDes Moines
$299
Find similar

United Airlines flights from Des Moines to San Luis Obispo

Our best United Airlines deals on Des Moines to San Luis Obispo flight tickets
United Airlines
Oct 25
DSM8:00 amDes Moines
16h 15m
3 stops
SBP10:15 pmSan Luis Obispo County
Oct 28
SBP6:25 pmSan Luis Obispo County
24h 20m
2 stops
DSM8:45 pmDes Moines
$453
Find similar
United Airlines
Oct 11
DSM8:00 amDes Moines
16h 14m
3 stops
SBP10:14 pmSan Luis Obispo County
Oct 17
SBP6:22 pmSan Luis Obispo County
14h 10m
2 stops
DSM10:32 amDes Moines
$524
Find similar
United Airlines
Mar 10
DSM11:30 amDes Moines
11h 54m
2 stops
SBP9:24 pmSan Luis Obispo County
Mar 12
SBP10:35 amSan Luis Obispo County
11h 04m
2 stops
DSM11:39 pmDes Moines
$785
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Des Moines to San Luis Obispo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 10/11

2:28 pm-6:27 pm

1 stop5h 59m

San Luis Obispo County

Fri 10/17

12:27 pm-10:56 pm

1 stop8h 29m

$289

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 10/11

5:00 am-11:37 am

1 stop8h 37m

San Luis Obispo County

Fri 10/17

7:16 pm-8:22 am

2 stops11h 06m

$294

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 10/25

5:00 am-11:57 am

2 stops8h 57m

San Luis Obispo County

Tue 10/28

6:05 am-4:17 pm

2 stops8h 12m

$299

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 10/11

5:00 am-11:57 am

2 stops8h 57m

San Luis Obispo County

Fri 10/17

7:16 pm-8:22 am

2 stops11h 06m

$410

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Thu 12/4

5:00 am-9:06 am

1 stop6h 06m

San Luis Obispo County

Sun 12/7

4:18 pm-11:59 pm

1 stop5h 41m

$423

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Thu 12/4

5:00 am-11:39 am

1 stop8h 39m

San Luis Obispo County

Sun 12/7

6:00 am-4:40 pm

2 stops8h 40m

$428

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Thu 12/4

8:50 am-6:29 pm

2 stops11h 39m

San Luis Obispo County

Sun 12/7

6:00 am-5:57 pm

2 stops9h 57m

$433

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 10/11

5:00 am-4:06 pm

2 stops13h 06m

San Luis Obispo County

Fri 10/17

7:16 pm-8:22 am

2 stops11h 06m

$436

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 10/25

8:00 am-10:15 pm

3 stops16h 15m

San Luis Obispo County

Tue 10/28

6:25 pm-8:45 pm

2 stops24h 20m

$453

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 10/11

8:00 am-10:14 pm

3 stops16h 14m

San Luis Obispo County

Fri 10/17

6:22 pm-10:32 am

2 stops14h 10m

$524

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to San Luis Obispo from

How to get the cheapest flight ticket from Des Moines to San Luis Obispo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Luis Obispo?

On average, the least expensive day to fly to San Luis Obispo from Des Moines is on a Friday. momondo users have found tickets for Friday departures for as low as $346. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Des Moines to San Luis Obispo for around $670.

What is the cheapest time of day to depart on your flight to San Luis Obispo?

Flying to San Luis Obispo from Des Moines in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $322 when looking at flights departing in the afternoon. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $502 on average. Flights to San Luis Obispo from Des Moines in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

When to book flights from Des Moines to San Luis Obispo

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Luis Obispo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Luis Obispo (DSM to SBP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Luis Obispo

Direct flights

None
There are no direct flights from Des Moines to San Luis Obispo. There are no popular flight routes from Des Moines to San Luis Obispo.
Search flight deals

  • How far is Des Moines to San Luis Obispo County by plane?

    The distance between Des Moines and San Luis Obispo County is about 1518.2 mi. 5h 59m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to San Luis Obispo County Airport?

    Prices for flights from Des Moines Airport to San Luis Obispo County Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Luis Obispo County Airport?

  • How old do you have to be to fly from Des Moines Airport to San Luis Obispo County Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Luis Obispo County Airport.

  • What documentation or ID do you need to fly to San Luis Obispo County Airport?

    The necessary travel and health documents for your San Luis Obispo County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Luis Obispo?

Best airlines flying from Des Moines to San Luis Obispo

Compare and see reviews for airlines that fly from Des Moines to San Luis Obispo with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $288Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
American AirlinesPriceFrom $288Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near San Luis Obispo?

Book flights to San Luis Obispo if you plan to visit one of these locations
Pismo Beach
Morro Bay
Cambria
Paso Robles
Avila Beach
San Simeon
Cayucos
Arroyo Grande
Atascadero
Grover Beach

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Luis Obispo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to San Luis Obispo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to San Luis Obispo with flexible booking policies on momondo?

Flights from Des Moines to San Luis Obispo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to San Luis Obispo?

momondo helps you find the best flight between Des Moines and San Luis Obispo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to San Luis Obispo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Luis Obispo, momondo offers a useful price alert feature which will track prices for flights to San Luis Obispo from Des Moines and alert you when they change.

An easier way to manage your San Luis Obispo trip

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