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Cheap flights from Des Moines to San Luis Obispo from $287

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Luis Obispo departing on 5/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to San Luis Obispo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:26 pm - 10:10 pm
DSM
-
SBP
5h 44m
1 stop
American Airlines Logo
7:02 pm - 8:26 am
SBP
-
DSM
11h 24m
2 stops
$374American Airlines
Fri, Apr 24 - Mon, Apr 27
American Airlines Logo
12:00 pm - 10:10 pm
DSM
-
SBP
12h 10m
2 stops
American Airlines Logo
7:02 pm - 10:26 am
SBP
-
DSM
13h 24m
2 stops
$379American Airlines
Fri, Apr 24 - Mon, Apr 27
American Airlines Logo
1:41 pm - 10:50 pm
DSM
-
SBP
11h 09m
2 stops
American Airlines Logo
4:05 pm - 11:48 pm
SBP
-
DSM
5h 43m
1 stop
$414American Airlines
Sat, Jul 18 - Sat, Jul 25
American Airlines Logo
5:45 am - 11:51 am
DSM
-
SBP
8h 06m
1 stop
American Airlines Logo
4:05 pm - 11:48 pm
SBP
-
DSM
5h 43m
1 stop
$459American Airlines
Sat, Jul 18 - Sat, Jul 25
American Airlines Logo
1:41 pm - 10:50 pm
DSM
-
SBP
11h 09m
2 stops
American Airlines Logo
12:31 pm - 12:29 am
SBP
-
DSM
9h 58m
2 stops
$470American Airlines
Sat, Jul 18 - Sat, Jul 25
American Airlines Logo
2:24 pm - 6:20 pm
DSM
-
SBP
5h 56m
1 stop
American Airlines Logo
6:00 am - 1:44 pm
SBP
-
DSM
5h 44m
1 stop
$471American Airlines
Sat, Jun 20 - Wed, Jun 24
American Airlines Logo
6:26 pm - 10:10 pm
DSM
-
SBP
5h 44m
1 stop
American Airlines Logo
12:55 pm - 11:59 pm
SBP
-
DSM
9h 04m
1 stop
$480American Airlines
Fri, Apr 24 - Mon, Apr 27
American Airlines Logo
2:24 pm - 6:20 pm
DSM
-
SBP
5h 56m
1 stop
American Airlines Logo
12:28 pm - 12:08 am
SBP
-
DSM
9h 40m
2 stops
$509American Airlines
Sat, Jun 20 - Wed, Jun 24
American Airlines Logo
6:26 pm - 10:10 pm
DSM
-
SBP
5h 44m
1 stop
American Airlines Logo
6:06 am - 1:47 pm
SBP
-
DSM
5h 41m
1 stop
$510American Airlines
Thu, May 14 - Tue, May 19
American Airlines Logo
12:00 pm - 10:10 pm
DSM
-
SBP
12h 10m
2 stops
American Airlines Logo
6:06 am - 1:47 pm
SBP
-
DSM
5h 41m
1 stop
$515American Airlines
Thu, May 14 - Tue, May 19

United Airlines flights from Des Moines to San Luis Obispo

Our best United Airlines deals on Des Moines to San Luis Obispo flight tickets
United Airlines
Apr 2
DSM5:17 pmDes Moines
6h 18m
1 stop
SBP9:35 pmSan Luis Obispo County
Apr 6
SBP6:15 amSan Luis Obispo County
8h 00m
2 stops
DSM4:15 pmDes Moines
$555
United Airlines
Apr 2
DSM1:41 pmDes Moines
12h 03m
2 stops
SBP11:44 pmSan Luis Obispo County
Apr 6
SBP6:15 amSan Luis Obispo County
8h 00m
2 stops
DSM4:15 pmDes Moines
$560
United Airlines
May 14
DSM11:40 amDes Moines
10h 20m
2 stops
SBP8:00 pmSan Luis Obispo County
May 19
SBP6:05 amSan Luis Obispo County
12h 11m
2 stops
DSM8:16 pmDes Moines
$664

American Airlines flights from Des Moines to San Luis Obispo

Our best American Airlines deals on Des Moines to San Luis Obispo flight tickets
American Airlines
Apr 24
DSM6:26 pmDes Moines
5h 44m
1 stop
SBP10:10 pmSan Luis Obispo County
Apr 27
SBP7:02 pmSan Luis Obispo County
11h 24m
2 stops
DSM8:26 amDes Moines
$374
American Airlines
Apr 24
DSM12:00 pmDes Moines
12h 10m
2 stops
SBP10:10 pmSan Luis Obispo County
Apr 27
SBP7:02 pmSan Luis Obispo County
13h 24m
2 stops
DSM10:26 amDes Moines
$379
American Airlines
Jul 18
DSM1:41 pmDes Moines
11h 09m
2 stops
SBP10:50 pmSan Luis Obispo County
Jul 25
SBP4:05 pmSan Luis Obispo County
5h 43m
1 stop
DSM11:48 pmDes Moines
$414

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from Des Moines to San Luis Obispo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Fri 4/24

6:26 pm-10:10 pm

1 stop5h 44m

San Luis Obispo County

Mon 4/27

7:02 pm-8:26 am

2 stops11h 24m

$374

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Fri 4/24

12:00 pm-10:10 pm

2 stops12h 10m

San Luis Obispo County

Mon 4/27

7:02 pm-10:26 am

2 stops13h 24m

$379

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 7/18

1:41 pm-10:50 pm

2 stops11h 09m

San Luis Obispo County

Sat 7/25

4:05 pm-11:48 pm

1 stop5h 43m

$414

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 7/18

5:45 am-11:51 am

1 stop8h 06m

San Luis Obispo County

Sat 7/25

4:05 pm-11:48 pm

1 stop5h 43m

$459

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 7/18

1:41 pm-10:50 pm

2 stops11h 09m

San Luis Obispo County

Sat 7/25

12:31 pm-12:29 am

2 stops9h 58m

$470

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 6/20

2:24 pm-6:20 pm

1 stop5h 56m

San Luis Obispo County

Wed 6/24

6:00 am-1:44 pm

1 stop5h 44m

$471

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Fri 4/24

6:26 pm-10:10 pm

1 stop5h 44m

San Luis Obispo County

Mon 4/27

12:55 pm-11:59 pm

1 stop9h 04m

$480

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 6/20

2:24 pm-6:20 pm

1 stop5h 56m

San Luis Obispo County

Wed 6/24

12:28 pm-12:08 am

2 stops9h 40m

$509
Quickest round-trip

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Thu 5/14

6:26 pm-10:10 pm

1 stop5h 44m

San Luis Obispo County

Tue 5/19

6:06 am-1:47 pm

1 stop5h 41m

$510

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Thu 5/14

12:00 pm-10:10 pm

2 stops12h 10m

San Luis Obispo County

Tue 5/19

6:06 am-1:47 pm

1 stop5h 41m

$515

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to San Luis Obispo from

How to get the cheapest flight ticket from Des Moines to San Luis Obispo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to San Luis Obispo County?

American Airlines, United Airlines, and Alaska Airlines are the most popular carriers operating from Des Moines to San Luis Obispo County

When to book flights from Des Moines to San Luis Obispo

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Luis Obispo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Luis Obispo (DSM to SBP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Luis Obispo

Fastest flight time

5h 33m

Direct flights

None
The fastest flight from Des Moines to San Luis Obispo takes 5h 33m
There are no direct flights from Des Moines to San Luis Obispo. There are no popular flight routes from Des Moines to San Luis Obispo.
Search flight deals

  • How far is Des Moines to San Luis Obispo County by plane?

    The distance between Des Moines and San Luis Obispo County is about 1518.2 mi. 5h 33m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to San Luis Obispo County Airport?

    Prices for flights from Des Moines Airport to San Luis Obispo County Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Luis Obispo County Airport?

  • How old do you have to be to fly from Des Moines Airport to San Luis Obispo County Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Luis Obispo County Airport.

  • What documentation or ID do you need to fly to San Luis Obispo County Airport?

    The necessary travel and health documents for your San Luis Obispo County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Luis Obispo?

Best airlines flying from Des Moines to San Luis Obispo

Compare and see reviews for airlines that fly from Des Moines to San Luis Obispo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $243Free CancellationRating
7.1
11,531 reviews
Search American Airlines flights

Traveling to a place near San Luis Obispo?

Book flights to San Luis Obispo if you plan to visit one of these locations
Pismo Beach
Morro Bay
Paso Robles
Cambria
Avila Beach
Cayucos
San Simeon
Arroyo Grande
Atascadero
Grover Beach

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Luis Obispo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to San Luis Obispo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to San Luis Obispo with flexible booking policies on momondo?

Flights from Des Moines to San Luis Obispo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to San Luis Obispo?

momondo helps you find the best flight between Des Moines and San Luis Obispo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to San Luis Obispo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Luis Obispo, momondo offers a useful price alert feature which will track prices for flights to San Luis Obispo from Des Moines and alert you when they change.

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