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Cheap flights from Des Moines to San Luis Obispo from $349

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to San Luis Obispo departing on 7/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to San Luis Obispo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:12 am - 11:43 am
DSM
-
SBP
8h 31m
1 stop
American Airlines Logo
6:00 am - 1:45 pm
SBP
-
DSM
5h 45m
1 stop
$349American Airlines
Sun, Jul 12 - Sat, Jul 18
American Airlines Logo
5:37 am - 11:49 am
DSM
-
SBP
8h 12m
1 stop
American Airlines Logo
7:02 pm - 9:11 am
SBP
-
DSM
12h 09m
2 stops
$354American Airlines
Sat, Jul 18 - Sat, Jul 25
American Airlines Logo
5:12 am - 11:49 am
DSM
-
SBP
8h 37m
2 stops
American Airlines Logo
7:02 pm - 9:11 am
SBP
-
DSM
12h 09m
2 stops
$359American Airlines
Sun, Jul 12 - Sat, Jul 18
American Airlines Logo
5:45 am - 11:47 am
DSM
-
SBP
8h 02m
1 stop
American Airlines Logo
12:40 pm - 11:58 pm
SBP
-
DSM
9h 18m
1 stop
$384American Airlines
Tue, Jun 30 - Thu, Jul 9
American Airlines Logo
5:37 am - 11:49 am
DSM
-
SBP
8h 12m
1 stop
American Airlines Logo
7:02 pm - 9:11 am
SBP
-
DSM
12h 09m
2 stops
$389American Airlines
Sat, Jul 18 - Sat, Jul 25
American Airlines Logo
5:12 am - 3:37 pm
DSM
-
SBP
12h 25m
2 stops
American Airlines Logo
7:02 pm - 9:11 am
SBP
-
DSM
12h 09m
2 stops
$394American Airlines
Wed, Jul 8 - Sun, Jul 12
United Airlines Logo
5:17 pm - 8:50 pm
DSM
-
SBP
5h 33m
1 stop
United Airlines Logo
8:28 pm - 10:26 am
SBP
-
DSM
11h 58m
2 stops
$418United Airlines
Wed, Aug 5 - Mon, Aug 10
American Airlines Logo
5:37 am - 11:49 am
DSM
-
SBP
8h 12m
1 stop
American Airlines Logo
4:07 pm - 11:48 pm
SBP
-
DSM
5h 41m
1 stop
$419American Airlines
Sat, Jul 18 - Sat, Jul 25
American Airlines Logo
5:37 am - 11:49 am
DSM
-
SBP
8h 12m
1 stop
American Airlines Logo
7:02 pm - 9:11 am
SBP
-
DSM
12h 09m
2 stops
$424American Airlines
Sat, Jul 18 - Sat, Jul 25
American Airlines Logo
5:37 am - 11:49 am
DSM
-
SBP
8h 12m
1 stop
American Airlines Logo
4:07 pm - 11:48 pm
SBP
-
DSM
5h 41m
1 stop
$429American Airlines
Sat, Jul 18 - Sat, Jul 25

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United Airlines flights from Des Moines to San Luis Obispo

Our best United Airlines deals on Des Moines to San Luis Obispo flight tickets
United Airlines
Aug 5
DSM5:17 pmDes Moines
5h 33m
1 stop
SBP8:50 pmSan Luis Obispo County
Aug 10
SBP8:28 pmSan Luis Obispo County
11h 58m
2 stops
DSM10:26 amDes Moines
$418
United Airlines
Aug 25
DSM9:13 amDes Moines
6h 11m
1 stop
SBP1:24 pmSan Luis Obispo County
Aug 29
SBP12:55 pmSan Luis Obispo County
5h 31m
1 stop
DSM8:26 pmDes Moines
$449
United Airlines
Aug 25
DSM1:10 pmDes Moines
9h 50m
2 stops
SBP9:00 pmSan Luis Obispo County
Aug 29
SBP12:55 pmSan Luis Obispo County
5h 31m
1 stop
DSM8:26 pmDes Moines
$454

American Airlines flights from Des Moines to San Luis Obispo

Our best American Airlines deals on Des Moines to San Luis Obispo flight tickets
American Airlines
Jul 12
DSM5:12 amDes Moines
8h 31m
1 stop
SBP11:43 amSan Luis Obispo County
Jul 18
SBP6:00 amSan Luis Obispo County
5h 45m
1 stop
DSM1:45 pmDes Moines
$349
American Airlines
Jul 18
DSM5:37 amDes Moines
8h 12m
1 stop
SBP11:49 amSan Luis Obispo County
Jul 25
SBP7:02 pmSan Luis Obispo County
12h 09m
2 stops
DSM9:11 amDes Moines
$354
American Airlines
Jul 12
DSM5:12 amDes Moines
8h 37m
2 stops
SBP11:49 amSan Luis Obispo County
Jul 18
SBP7:02 pmSan Luis Obispo County
12h 09m
2 stops
DSM9:11 amDes Moines
$359

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 20, 2026.
Use the filters below to find and compare flights from Des Moines to San Luis Obispo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sun 7/12

5:12 am-11:43 am

1 stop8h 31m

San Luis Obispo County

Sat 7/18

6:00 am-1:45 pm

1 stop5h 45m

$349

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 7/18

5:37 am-11:49 am

1 stop8h 12m

San Luis Obispo County

Sat 7/25

7:02 pm-9:11 am

2 stops12h 09m

$354

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sun 7/12

5:12 am-11:49 am

2 stops8h 37m

San Luis Obispo County

Sat 7/18

7:02 pm-9:11 am

2 stops12h 09m

$359

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Tue 6/30

5:45 am-11:47 am

1 stop8h 02m

San Luis Obispo County

Thu 7/9

12:40 pm-11:58 pm

1 stop9h 18m

$384

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 7/18

5:37 am-11:49 am

1 stop8h 12m

San Luis Obispo County

Sat 7/25

7:02 pm-9:11 am

2 stops12h 09m

$389

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Wed 7/8

5:12 am-3:37 pm

2 stops12h 25m

San Luis Obispo County

Sun 7/12

7:02 pm-9:11 am

2 stops12h 09m

$394

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Wed 8/5

5:17 pm-8:50 pm

1 stop5h 33m

San Luis Obispo County

Mon 8/10

8:28 pm-10:26 am

2 stops11h 58m

$418
Quickest round-trip

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 7/18

5:37 am-11:49 am

1 stop8h 12m

San Luis Obispo County

Sat 7/25

4:07 pm-11:48 pm

1 stop5h 41m

$419

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 7/18

5:37 am-11:49 am

1 stop8h 12m

San Luis Obispo County

Sat 7/25

7:02 pm-9:11 am

2 stops12h 09m

$424

Des MoinesSan Luis Obispo

DSM - SBP

DSMSBP

Des Moines

Sat 7/18

5:37 am-11:49 am

1 stop8h 12m

San Luis Obispo County

Sat 7/25

4:07 pm-11:48 pm

1 stop5h 41m

$429

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Des Moines to San Luis Obispo

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to San Luis Obispo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to San Luis Obispo (DSM to SBP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to San Luis Obispo

Fastest flight time

5h 33m

Direct flights

None
The fastest flight from Des Moines to San Luis Obispo takes 5h 33m
There are no direct flights from Des Moines to San Luis Obispo. There are no popular flight routes from Des Moines to San Luis Obispo.
Search flight deals

Frequently asked questions about flying from Des Moines to San Luis Obispo

  • How far is Des Moines to San Luis Obispo County by plane?

    The distance between Des Moines and San Luis Obispo County is about 1518.2 mi. 5h 33m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to San Luis Obispo County Airport?

    Prices for flights from Des Moines Airport to San Luis Obispo County Airport are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to San Luis Obispo County Airport?

  • How old do you have to be to fly from Des Moines Airport to San Luis Obispo County Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to San Luis Obispo County Airport.

  • What documentation or ID do you need to fly to San Luis Obispo County Airport?

    The necessary travel and health documents for your San Luis Obispo County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to San Luis Obispo?

Best airlines flying from Des Moines to San Luis Obispo

Compare and see reviews for airlines that fly from Des Moines to San Luis Obispo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $288Free CancellationRating
7.1
11,716 reviews
Search American Airlines flights

Frequently asked questions about flying from Des Moines to San Luis Obispo

  • How do I get Price Alerts for flights from Des Moines to San Luis Obispo?

    Confirm your travel details to search for the latest offers for flights from Des Moines to San Luis Obispo. While browsing offers there will be the option to toggle “Price Alerts”. You’ll then receive updates when prices for the flight route increase or decrease.

  • How can I save money on flights from Des Moines to San Luis Obispo with momondo?

    Plan your trips smart with the “Price Forecast” feature, which uses flight data to help you pick the best days to fly for the lowest fares. Our “Price Calendar” helps you get the most for your money by showing you when it’s most advantageous to fly. Curate your own travel experiences for less with “Explore”. Expert travel hacks to fuel your next adventure are a click away with “Discover” by momondo. Set up our “Price Alerts” to track fare changes and book when prices are at their lowest point.

  • How does momondo find its flight prices?

    We aggregate our prices from over 700+ competitors from airlines to OTAs. We operate in over 30 markets worldwide to show you a wide range of travel options.

Traveling to a place near San Luis Obispo?

Book flights to San Luis Obispo if you plan to visit one of these locations
Pismo Beach
Paso Robles
Morro Bay
Cambria
Avila Beach
San Simeon
Cayucos
Arroyo Grande
Atascadero
Grover Beach

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to San Luis Obispo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to San Luis Obispo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to San Luis Obispo with flexible booking policies on momondo?

Flights from Des Moines to San Luis Obispo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to San Luis Obispo?

momondo helps you find the best flight between Des Moines and San Luis Obispo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to San Luis Obispo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to San Luis Obispo, momondo offers a useful price alert feature which will track prices for flights to San Luis Obispo from Des Moines and alert you when they change.

An easier way to manage your San Luis Obispo trip

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Mon 7/20
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