Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Des Moines to Amarillo from $164

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Amarillo departing on 4/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Amarillo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:37 pm - 11:59 pm
DSM
-
AMA
4h 22m
1 stop
American Airlines Logo
5:00 am - 10:34 am
AMA
-
DSM
5h 34m
1 stop
$387American Airlines
Mon, Mar 23 - Tue, Mar 31
American Airlines Logo
7:37 pm - 11:59 pm
DSM
-
AMA
4h 22m
1 stop
American Airlines Logo
12:31 pm - 11:48 pm
AMA
-
DSM
11h 17m
2 stops
$392American Airlines
Mon, Mar 23 - Tue, Mar 31
United Airlines Logo
2:59 pm - 10:38 pm
DSM
-
AMA
7h 39m
1 stop
United Airlines Logo
3:04 pm - 10:43 pm
AMA
-
DSM
7h 39m
1 stop
$397United Airlines
Sat, Mar 28 - Wed, Apr 1
United Airlines Logo
6:12 am - 2:29 pm
DSM
-
AMA
8h 17m
1 stop
United Airlines Logo
5:19 pm - 11:42 pm
AMA
-
DSM
6h 23m
1 stop
$455United Airlines
Sat, Mar 28 - Wed, Apr 1
United Airlines Logo
6:12 am - 11:29 am
DSM
-
AMA
5h 17m
1 stop
United Airlines Logo
3:04 pm - 10:43 pm
AMA
-
DSM
7h 39m
1 stop
$457United Airlines
Sat, Mar 28 - Wed, Apr 1
Southwest Logo
6:40 am - 10:05 pm
DSM
-
AMA
15h 25m
2 stops
Southwest Logo
11:00 am - 9:45 pm
AMA
-
DSM
10h 45m
2 stops
$463Southwest
Tue, Mar 24 - Sat, Mar 28
American Airlines Logo
4:50 pm - 11:59 pm
DSM
-
AMA
7h 09m
1 stop
American Airlines Logo
10:14 am - 4:03 pm
AMA
-
DSM
5h 49m
1 stop
$468American Airlines
Sun, Jun 21 - Tue, Jun 23
Southwest Logo
5:20 am - 2:50 pm
DSM
-
AMA
9h 30m
2 stops
Southwest Logo
11:40 am - 9:15 pm
AMA
-
DSM
9h 35m
2 stops
$477Southwest
Sun, May 17 - Wed, May 20
American Airlines Logo
3:26 pm - 8:06 pm
DSM
-
AMA
4h 40m
1 stop
American Airlines Logo
6:34 pm - 11:46 pm
AMA
-
DSM
5h 12m
1 stop
$478American Airlines
Tue, Mar 24 - Sat, Mar 28
Southwest Logo
5:10 am - 1:10 pm
DSM
-
AMA
8h 00m
2 stops
Southwest Logo
10:50 am - 9:40 pm
AMA
-
DSM
10h 50m
2 stops
$482Southwest
Sat, Jul 25 - Wed, Jul 29

American Airlines flights from Des Moines to Amarillo

Our best American Airlines deals on Des Moines to Amarillo flight tickets
American Airlines
Mar 23
DSM7:37 pmDes Moines
4h 22m
1 stop
AMA11:59 pmAmarillo
Mar 31
AMA5:00 amAmarillo
5h 34m
1 stop
DSM10:34 amDes Moines
$387
American Airlines
Mar 23
DSM7:37 pmDes Moines
4h 22m
1 stop
AMA11:59 pmAmarillo
Mar 31
AMA12:31 pmAmarillo
11h 17m
2 stops
DSM11:48 pmDes Moines
$392
American Airlines
Jun 21
DSM4:50 pmDes Moines
7h 09m
1 stop
AMA11:59 pmAmarillo
Jun 23
AMA10:14 amAmarillo
5h 49m
1 stop
DSM4:03 pmDes Moines
$468

United Airlines flights from Des Moines to Amarillo

Our best United Airlines deals on Des Moines to Amarillo flight tickets
United Airlines
Mar 28
DSM2:59 pmDes Moines
7h 39m
1 stop
AMA10:38 pmAmarillo
Apr 1
AMA3:04 pmAmarillo
7h 39m
1 stop
DSM10:43 pmDes Moines
$397
United Airlines
Mar 28
DSM6:12 amDes Moines
8h 17m
1 stop
AMA2:29 pmAmarillo
Apr 1
AMA5:19 pmAmarillo
6h 23m
1 stop
DSM11:42 pmDes Moines
$455
United Airlines
Mar 28
DSM6:12 amDes Moines
5h 17m
1 stop
AMA11:29 amAmarillo
Apr 1
AMA3:04 pmAmarillo
7h 39m
1 stop
DSM10:43 pmDes Moines
$457

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Amarillo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from Des Moines to Amarillo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Mon 3/23

7:37 pm-11:59 pm

1 stop4h 22m

Amarillo

Tue 3/31

5:00 am-10:34 am

1 stop5h 34m

$387

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Mon 3/23

7:37 pm-11:59 pm

1 stop4h 22m

Amarillo

Tue 3/31

12:31 pm-11:48 pm

2 stops11h 17m

$392

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sat 3/28

2:59 pm-10:38 pm

1 stop7h 39m

Amarillo

Wed 4/1

3:04 pm-10:43 pm

1 stop7h 39m

$397

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sat 3/28

6:12 am-2:29 pm

1 stop8h 17m

Amarillo

Wed 4/1

5:19 pm-11:42 pm

1 stop6h 23m

$455

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sat 3/28

6:12 am-11:29 am

1 stop5h 17m

Amarillo

Wed 4/1

3:04 pm-10:43 pm

1 stop7h 39m

$457

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 3/24

6:40 am-10:05 pm

2 stops15h 25m

Amarillo

Sat 3/28

11:00 am-9:45 pm

2 stops10h 45m

$463

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sun 6/21

4:50 pm-11:59 pm

1 stop7h 09m

Amarillo

Tue 6/23

10:14 am-4:03 pm

1 stop5h 49m

$468

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sun 5/17

5:20 am-2:50 pm

2 stops9h 30m

Amarillo

Wed 5/20

11:40 am-9:15 pm

2 stops9h 35m

$477
Quickest round-trip

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Tue 3/24

3:26 pm-8:06 pm

1 stop4h 40m

Amarillo

Sat 3/28

6:34 pm-11:46 pm

1 stop5h 12m

$478

Des MoinesAmarillo

DSM - AMA

DSMAMA

Des Moines

Sat 7/25

5:10 am-1:10 pm

2 stops8h 00m

Amarillo

Wed 7/29

10:50 am-9:40 pm

2 stops10h 50m

$482

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

See travel insights to Amarillo from

How to get the cheapest flight ticket from Des Moines to Amarillo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Amarillo?

United Airlines, American Airlines, and Southwest are the most popular carriers operating from Des Moines to Amarillo

When to book flights from Des Moines to Amarillo

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Amarillo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Amarillo (DSM to AMA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Amarillo

Fastest flight time

7h 39m

Direct flights

None
The fastest flight from Des Moines to Amarillo takes 7h 39m
There are no direct flights from Des Moines to Amarillo. There are no popular flight routes from Des Moines to Amarillo.
Search flight deals

  • How far is Des Moines to Amarillo by plane?

    The straight-line distance from Des Moines to Amarillo is 623.9 mi. 7h 39m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Amarillo Airport?

    Prices for flights from Des Moines Airport to Amarillo Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Des Moines Airport to Amarillo Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Amarillo Airport.

  • What documentation or ID do you need to fly to Amarillo Airport?

    The required travel and health documents for your Amarillo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Amarillo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Amarillo?

Book flights to Amarillo if you plan to visit one of these locations
Dalhart
Dumas

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Amarillo?

Finding the right flight to Amarillo from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Amarillo quick and easy, saving you time and money.

Can I find flights from Des Moines to Amarillo with flexible booking policies on momondo?

Flights from Des Moines to Amarillo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Amarillo?

momondo provides multiple filters to help you find the best flight to Amarillo from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Amarillo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Amarillo, momondo offers a useful price alert feature which will track prices for flights to Amarillo from Des Moines and alert you when they change.

An easier way to manage your Amarillo trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 4/11
Sat 4/18
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States