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Cheap flights from Columbia, Missouri to San Francisco from $342

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to San Francisco departing on 2/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbia, Missouri to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:27 pm - 5:05 pm
COU
-
SFO
6h 38m1 stop
American Airlines Logo
8:00 am - 5:31 pm
SFO
-
COU
7h 31m1 stop
$342American Airlines
Tue, Feb 24 - Tue, Mar 3
American Airlines Logo
12:27 pm - 7:48 pm
COU
-
SFO
9h 21m1 stop
American Airlines Logo
11:05 am - 10:40 pm
SFO
-
COU
9h 35m2 stops
$348American Airlines
Tue, Feb 24 - Tue, Mar 3
American Airlines Logo
7:10 am - 5:47 pm
COU
-
SFO
12h 37m2 stops
American Airlines Logo
10:22 am - 10:40 pm
SFO
-
COU
10h 18m2 stops
$353American Airlines
Tue, Feb 24 - Tue, Mar 3
United Airlines Logo
3:10 pm - 9:30 pm
COU
-
SFO
8h 20m1 stop
United Airlines Logo
12:25 pm - 9:37 pm
SFO
-
COU
7h 12m1 stop
$388United Airlines
Sat, Jan 10 - Tue, Jan 13
American Airlines Logo
12:27 pm - 8:42 pm
COU
-
SFO
10h 15m2 stops
American Airlines Logo
6:44 am - 5:28 pm
SFO
-
COU
8h 44m2 stops
$434American Airlines
Wed, Feb 18 - Sat, Feb 28
United Airlines Logo
8:45 am - 3:57 pm
COU
-
SFO
9h 12m1 stop
United Airlines Logo
8:25 am - 5:25 pm
SFO
-
COU
7h 00m1 stop
$439United Airlines
Thu, Dec 25 - Thu, Jan 1
United Airlines Logo
8:45 am - 3:27 pm
COU
-
SFO
8h 42m1 stop
United Airlines Logo
4:48 pm - 10:42 am
SFO
-
COU
15h 54m2 stops
$442United Airlines
Sat, Jan 10 - Tue, Jan 13
United Airlines Logo
3:10 pm - 9:30 pm
COU
-
SFO
8h 20m1 stop
United Airlines Logo
1:25 pm - 10:42 am
SFO
-
COU
19h 17m2 stops
$452United Airlines
Sat, Jan 10 - Tue, Jan 13
United Airlines Logo
8:45 am - 3:27 pm
COU
-
SFO
8h 42m1 stop
United Airlines Logo
9:20 pm - 8:40 pm
SFO
-
COU
21h 20m1 stop
$507United Airlines
Wed, Feb 11 - Fri, Feb 13
United Airlines Logo
8:45 am - 9:39 pm
COU
-
SFO
14h 54m2 stops
United Airlines Logo
7:00 am - 8:33 pm
SFO
-
COU
11h 33m2 stops
$540United Airlines
Sat, Jan 10 - Tue, Jan 13

United Airlines flights from Columbia, Missouri to San Francisco

Our best United Airlines deals on Columbia, Missouri to San Francisco flight tickets
United Airlines
Jan 10
COU3:10 pmColumbia Regional
8h 20m
1 stop
SFO9:30 pmSan Francisco
Jan 13
SFO12:25 pmSan Francisco
7h 12m
1 stop
COU9:37 pmColumbia Regional
$388
Find similar
United Airlines
Dec 25
COU8:45 amColumbia Regional
9h 12m
1 stop
SFO3:57 pmSan Francisco
Jan 1
SFO8:25 amSan Francisco
7h 00m
1 stop
COU5:25 pmColumbia Regional
$439
Find similar
United Airlines
Jan 10
COU8:45 amColumbia Regional
8h 42m
1 stop
SFO3:27 pmSan Francisco
Jan 13
SFO4:48 pmSan Francisco
15h 54m
2 stops
COU10:42 amColumbia Regional
$442
Find similar

American Airlines flights from Columbia, Missouri to San Francisco

Our best American Airlines deals on Columbia, Missouri to San Francisco flight tickets
American Airlines
Feb 24
COU12:27 pmColumbia Regional
6h 38m
1 stop
SFO5:05 pmSan Francisco
Mar 3
SFO8:00 amSan Francisco
7h 31m
1 stop
COU5:31 pmColumbia Regional
$342
Find similar
American Airlines
Feb 24
COU12:27 pmColumbia Regional
6h 38m
1 stop
SFO5:05 pmSan Francisco
Mar 3
SFO6:44 amSan Francisco
8h 39m
2 stops
COU5:23 pmColumbia Regional
$348
Find similar
American Airlines
Feb 24
COU7:10 amColumbia Regional
13h 32m
2 stops
SFO6:42 pmSan Francisco
Mar 3
SFO6:44 amSan Francisco
8h 47m
2 stops
COU5:31 pmColumbia Regional
$353
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Columbia, Missouri to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Tue 2/24

12:27 pm-5:05 pm

1 stop6h 38m

San Francisco

Tue 3/3

8:00 am-5:31 pm

1 stop7h 31m

$342

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Tue 2/24

12:27 pm-7:48 pm

1 stop9h 21m

San Francisco

Tue 3/3

11:05 am-10:40 pm

2 stops9h 35m

$348

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Tue 2/24

7:10 am-5:47 pm

2 stops12h 37m

San Francisco

Tue 3/3

10:22 am-10:40 pm

2 stops10h 18m

$353

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 1/10

3:10 pm-9:30 pm

1 stop8h 20m

San Francisco

Tue 1/13

12:25 pm-9:37 pm

1 stop7h 12m

$388

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Wed 2/18

12:27 pm-8:42 pm

2 stops10h 15m

San Francisco

Sat 2/28

6:44 am-5:28 pm

2 stops8h 44m

$434

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Thu 12/25

8:45 am-3:57 pm

1 stop9h 12m

San Francisco

Thu 1/1

8:25 am-5:25 pm

1 stop7h 00m

$439

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 1/10

8:45 am-3:27 pm

1 stop8h 42m

San Francisco

Tue 1/13

4:48 pm-10:42 am

2 stops15h 54m

$442

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 1/10

3:10 pm-9:30 pm

1 stop8h 20m

San Francisco

Tue 1/13

1:25 pm-10:42 am

2 stops19h 17m

$452

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Wed 2/11

8:45 am-3:27 pm

1 stop8h 42m

San Francisco

Fri 2/13

9:20 pm-8:40 pm

1 stop21h 20m

$507

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 1/10

8:45 am-9:39 pm

2 stops14h 54m

San Francisco

Tue 1/13

7:00 am-8:33 pm

2 stops11h 33m

$540

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Columbia, Missouri to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of March, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $386.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Columbia, Missouri to San Francisco is on a Saturday when prices can be found for as low as $530. The most expensive day to fly to San Francisco is Friday, with ticket prices averaging around $697.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Columbia, Missouri to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $556. Flights in the evening are often more expensive with an average ticket price of $635.

When to book flights from Columbia, Missouri to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to San Francisco (COU to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to San Francisco

Fastest flight time

7h 29m

Direct flights

None
The fastest flight from Columbia, Missouri to San Francisco takes 7h 29m
There are no direct flights from Columbia, Missouri to San Francisco. There are no popular flight routes from Columbia, Missouri to San Francisco.
Search flight deals

  • How far is Columbia Regional to San Francisco by plane?

    There are 1622.8 mi between Columbia Regional and San Francisco. Typically, this will take 7h 29m by plane in normal conditions.

  • When did momondo last update prices for flights from Columbia Regional Airport to San Francisco Airport?

    Prices for flights from Columbia Regional Airport to San Francisco Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbia Regional Airport to San Francisco Airport?

  • How old do you have to be to fly from Columbia Regional Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia, Missouri to San Francisco?

Best airlines flying from Columbia, Missouri to San Francisco

Compare and see reviews for airlines that fly from Columbia, Missouri to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $377Free CancellationRating
7.2
11,052 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

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Santa Cruz
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Sonoma
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Roseville
Hayward
Calistoga
Big Sur
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Santa Clara
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Half Moon Bay
Vallejo
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Sunnyvale
Turlock

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Columbia to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Columbia to San Francisco with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Francisco from Columbia with this policy.

How can momondo help me find flights from Columbia to San Francisco?

Once all potential Columbia to San Francisco flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Columbia. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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