Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Columbia, Missouri to San Francisco from $318

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia, Missouri to San Francisco departing on 4/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Columbia, Missouri to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
4:28 pm - 11:59 pm
COU
-
SFO
9h 31m
1 stop
American Airlines Logo
5:30 am - 3:58 pm
SFO
-
COU
8h 28m
1 stop
$358American Airlines
Thu, Apr 23 - Mon, Apr 27
American Airlines Logo
12:06 pm - 7:04 pm
COU
-
SFO
8h 58m
2 stops
American Airlines Logo
11:52 am - 9:30 pm
SFO
-
COU
7h 38m
1 stop
$364American Airlines
Sat, Apr 18 - Sat, Apr 25
American Airlines Logo
12:06 pm - 7:04 pm
COU
-
SFO
8h 58m
2 stops
American Airlines Logo
6:00 am - 4:51 pm
SFO
-
COU
8h 51m
2 stops
$369American Airlines
Sat, Apr 18 - Sat, Apr 25
United Airlines Logo
9:02 am - 1:15 pm
COU
-
SFO
6h 13m
1 stop
United Airlines Logo
10:50 pm - 10:55 am
SFO
-
COU
10h 05m
1 stop
$408United Airlines
Tue, Apr 7 - Sat, Apr 11
American Airlines Logo
10:13 am - 5:58 pm
COU
-
SFO
9h 45m
1 stop
American Airlines Logo
7:10 am - 7:13 pm
SFO
-
COU
10h 03m
2 stops
$414American Airlines
Tue, Apr 7 - Sat, Apr 11
American Airlines Logo
5:19 pm - 10:28 pm
COU
-
SFO
7h 09m
1 stop
American Airlines Logo
11:16 pm - 9:52 am
SFO
-
COU
8h 36m
1 stop
$455American Airlines
Tue, Jul 7 - Sat, Jul 11
American Airlines Logo
4:28 pm - 10:00 pm
COU
-
SFO
7h 32m
1 stop
American Airlines Logo
5:40 am - 4:51 pm
SFO
-
COU
9h 11m
2 stops
$461American Airlines
Fri, Apr 24 - Wed, Apr 29
American Airlines Logo
5:21 pm - 11:54 pm
COU
-
SFO
8h 33m
1 stop
American Airlines Logo
12:59 am - 11:35 am
SFO
-
COU
8h 36m
1 stop
$463American Airlines
Thu, Apr 23 - Sun, Apr 26
American Airlines Logo
6:55 am - 5:36 pm
COU
-
SFO
12h 41m
2 stops
American Airlines Logo
10:20 am - 9:29 pm
SFO
-
COU
9h 09m
1 stop
$464American Airlines
Sat, May 23 - Wed, May 27
American Airlines Logo
5:21 pm - 11:54 pm
COU
-
SFO
8h 33m
1 stop
American Airlines Logo
6:00 am - 4:51 pm
SFO
-
COU
8h 51m
2 stops
$469American Airlines
Thu, Apr 23 - Mon, Apr 27

American Airlines flights from Columbia, Missouri to San Francisco

Our best American Airlines deals on Columbia, Missouri to San Francisco flight tickets
American Airlines
Apr 23
COU4:28 pmColumbia Regional
9h 31m
1 stop
SFO11:59 pmSan Francisco
Apr 27
SFO5:30 amSan Francisco
8h 28m
1 stop
COU3:58 pmColumbia Regional
$358
American Airlines
Apr 18
COU12:06 pmColumbia Regional
8h 58m
2 stops
SFO7:04 pmSan Francisco
Apr 25
SFO11:52 amSan Francisco
7h 38m
1 stop
COU9:30 pmColumbia Regional
$364
American Airlines
Apr 18
COU12:06 pmColumbia Regional
8h 58m
2 stops
SFO7:04 pmSan Francisco
Apr 25
SFO6:00 amSan Francisco
8h 51m
2 stops
COU4:51 pmColumbia Regional
$369

United Airlines flights from Columbia, Missouri to San Francisco

Our best United Airlines deals on Columbia, Missouri to San Francisco flight tickets
United Airlines
Apr 7
COU9:02 amColumbia Regional
6h 13m
1 stop
SFO1:15 pmSan Francisco
Apr 11
SFO10:50 pmSan Francisco
10h 05m
1 stop
COU10:55 amColumbia Regional
$408
United Airlines
May 19
COU5:00 amColumbia Regional
8h 24m
1 stop
SFO11:24 amSan Francisco
May 26
SFO12:50 amSan Francisco
7h 58m
1 stop
COU10:48 amColumbia Regional
$473
United Airlines
May 19
COU5:00 amColumbia Regional
8h 24m
1 stop
SFO11:24 amSan Francisco
May 27
SFO6:00 amSan Francisco
12h 39m
2 stops
COU8:39 pmColumbia Regional
$537

momondo Fare Finder

 
Customize your flight search to find flights from Columbia, Missouri to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Columbia, Missouri to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Thu 4/23

4:28 pm-11:59 pm

1 stop9h 31m

San Francisco

Mon 4/27

5:30 am-3:58 pm

1 stop8h 28m

$358

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 4/18

12:06 pm-7:04 pm

2 stops8h 58m

San Francisco

Sat 4/25

11:52 am-9:30 pm

1 stop7h 38m

$364

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 4/18

12:06 pm-7:04 pm

2 stops8h 58m

San Francisco

Sat 4/25

6:00 am-4:51 pm

2 stops8h 51m

$369

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Tue 4/7

9:02 am-1:15 pm

1 stop6h 13m

San Francisco

Sat 4/11

10:50 pm-10:55 am

1 stop10h 05m

$408

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Tue 4/7

10:13 am-5:58 pm

1 stop9h 45m

San Francisco

Sat 4/11

7:10 am-7:13 pm

2 stops10h 03m

$414
Quickest round-trip

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Tue 7/7

5:19 pm-10:28 pm

1 stop7h 09m

San Francisco

Sat 7/11

11:16 pm-9:52 am

1 stop8h 36m

$455

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Fri 4/24

4:28 pm-10:00 pm

1 stop7h 32m

San Francisco

Wed 4/29

5:40 am-4:51 pm

2 stops9h 11m

$461

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Thu 4/23

5:21 pm-11:54 pm

1 stop8h 33m

San Francisco

Sun 4/26

12:59 am-11:35 am

1 stop8h 36m

$463

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Sat 5/23

6:55 am-5:36 pm

2 stops12h 41m

San Francisco

Wed 5/27

10:20 am-9:29 pm

1 stop9h 09m

$464

ColumbiaSan Francisco

COU - SFO

COUSFO

Columbia Regional

Thu 4/23

5:21 pm-11:54 pm

1 stop8h 33m

San Francisco

Mon 4/27

6:00 am-4:51 pm

2 stops8h 51m

$469

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

See travel insights to San Francisco from

How to get the cheapest flight ticket from Columbia, Missouri to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of March, then flying in January is also cheap. Prices for this month can be found on momondo for an average of $323.

When to book flights from Columbia, Missouri to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia, Missouri to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia, Missouri to San Francisco (COU to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia, Missouri to San Francisco

Fastest flight time

6h 13m

Direct flights

None
The fastest flight from Columbia, Missouri to San Francisco takes 6h 13m
There are no direct flights from Columbia, Missouri to San Francisco. There are no popular flight routes from Columbia, Missouri to San Francisco.
Search flight deals

  • How far is Columbia Regional to San Francisco by plane?

    There are 1622.8 mi between Columbia Regional and San Francisco. Typically, this will take 6h 13m by plane in normal conditions.

  • When did momondo last update prices for flights from Columbia Regional Airport to San Francisco Airport?

    Prices for flights from Columbia Regional Airport to San Francisco Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Columbia Regional Airport to San Francisco Airport?

  • How old do you have to be to fly from Columbia Regional Airport to San Francisco Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Regional Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The necessary travel and health documents for your San Francisco Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Columbia, Missouri to San Francisco?

Best airlines flying from Columbia, Missouri to San Francisco

Compare and see reviews for airlines that fly from Columbia, Missouri to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $278Free CancellationRating
7.4
9,460 reviews
Search United Airlines flights
American AirlinesPriceFrom $362Free CancellationRating
7.1
11,489 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Walnut Creek
Roseville
Hayward
Berkeley
Santa Clara
Big Sur
Fremont
Calistoga
Vallejo
Salinas
Half Moon Bay
Daly City
Milpitas
Pacific Grove
South San Francisco

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to San Francisco?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Columbia to San Francisco. momondo saves you time and could save you money on your trip.

Can I find flights from Columbia to San Francisco with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to San Francisco from Columbia with this policy.

How can momondo help me find flights from Columbia to San Francisco?

Once all potential Columbia to San Francisco flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Columbia to San Francisco right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to San Francisco from Columbia. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 4/22
Wed 4/29
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States