Cheap flights from Des Moines (DSM) from $44

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Fly to

Route

Depart

Return

Price

Cheapest one-way

Des MoinesLas Vegas

DSM Des Moines - LAS Las Vegas Harry Reid Intl

DSMLAS

Des Moines

Mon 9/28

9:31 pm-10:41 pm

Nonstop3h 10m

$44

Des MoinesLas Vegas

DSM Des Moines - LAS Las Vegas Harry Reid Intl

DSMLAS

Des Moines

Mon 9/21

9:31 pm-10:41 pm

Nonstop3h 10m

$50

Quickest one-way

Des MoinesDenver

DSM Des Moines - DEN Denver Intl

DSMDEN

Des Moines

Thu 10/1

11:29 am-12:26 pm

Nonstop1h 57m

$73

Des MoinesDenver

DSM Des Moines - DEN Denver Intl

DSMDEN

Des Moines

Thu 12/3

8:35 pm-9:43 pm

Nonstop2h 08m

$74

Des MoinesPhoenix

DSM Des Moines - PHX Phoenix Sky Harbor Intl

DSMPHX

Des Moines

Mon 11/16

8:04 pm-1:30 pm

1 stop18h 26m

$78

Des MoinesPhoenix

DSM Des Moines - PHX Phoenix Sky Harbor Intl

DSMPHX

Des Moines

Sun 9/27

9:56 pm-10:47 pm

1 stop26h 51m

$86

Des MoinesDenver

DSM Des Moines - DEN Denver Intl

DSMDEN

Des Moines

Tue 10/6

1:27 pm-2:35 pm

Nonstop2h 08m

$119

Des MoinesDenver

DSM Des Moines - DEN Denver Intl

DSMDEN

Des Moines

Sat 9/26

5:22 pm-6:25 pm

Nonstop2h 03m

$119

Des MoinesDenver

DSM Des Moines - DEN Denver Intl

DSMDEN

Des Moines

Mon 11/2

4:25 pm-11:10 pm

2 stops7h 45m

$134

Des MoinesDenver

DSM Des Moines - DEN Denver Intl

DSMDEN

Des Moines

Wed 12/2

12:05 pm-8:50 pm

2 stops9h 45m

$134

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

Where can I directly fly to from Des Moines?

Currently, 16 destinations can be reached directly via flights from Des Moines.

Flights from Des Moines to

Atlanta

from$154

Flights from Des Moines to

Austin

from$113

Flights from Des Moines to

Boston

from$70

Flights from Des Moines to

Fort Lauderdale

from$94

Flights from Des Moines to

Fort Myers

from$76

Flights from Des Moines to

Jacksonville

from$100

Flights from Des Moines to

Las Vegas

from$49

Flights from Des Moines to

Los Angeles

from$139

Flights from Des Moines to

Miami

from$358

Flights from Des Moines to

Minneapolis

from$177

Flights from Des Moines to

Nashville

from$113

Flights from Des Moines to

Philadelphia

from$43

Flights from Des Moines to

Punta Gorda

from$120

Flights from Des Moines to

Santa Ana, California

from$77

Flights from Des Moines to

Sarasota

from$65

Flights from Des Moines to

Tampa

from$71

Find the cheapest flights from Des Moines

One-way

Last minute

International

Domestic

Cheap one-way flights from Des Moines

Enter your travel dates to find the best prices.

9:31 pm - 10:41 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 10mnonstop

$44Allegiant Air

Mon, Sep 28

9:31 pm - 10:41 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 10mnonstop

$50Allegiant Air

Mon, Sep 21

11:29 am - 12:26 pmDSM Des Moines-DEN Denver Intl

1h 57mnonstop

$73Frontier

Thu, Oct 1

8:35 pm - 9:43 pmDSM Des Moines-DEN Denver Intl

2h 08mnonstop

$74Frontier

Thu, Dec 3

8:04 pm - 1:30 pmDSM Des Moines-PHX Phoenix Sky Harbor Intl

18h 26m1 stop Las Vegas Harry Reid Intl

$78Multiple Airlines

Mon, Nov 16

9:56 pm - 10:47 pmDSM Des Moines-PHX Phoenix Sky Harbor Intl

26h 51m1 stop Las Vegas Harry Reid Intl

$86Multiple Airlines

Sun, Sep 27

1:27 pm - 2:35 pmDSM Des Moines-DEN Denver Intl

2h 08mnonstop

$119United Airlines

Tue, Oct 6

5:22 pm - 6:25 pmDSM Des Moines-DEN Denver Intl

2h 03mnonstop

$119United Airlines

Sat, Sep 26

4:25 pm - 11:10 pmDSM Des Moines-DEN Denver Intl

7h 45m2 stops Chicago Midway Lambert-St Louis

$134Southwest

Mon, Nov 2

12:05 pm - 8:50 pmDSM Des Moines-DEN Denver Intl

9h 45m2 stops Las Vegas Harry Reid Intl Phoenix Sky Harbor Intl

$134Southwest

Wed, Dec 2

Last-minute flight deals from Des Moines

Enter your travel dates to find the best prices.

9:31 pm - 10:41 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 10mnonstop

2:53 pm - 7:48 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$222Allegiant Air

Fri, Sep 11 - Fri, Sep 18

8:30 pm - 11:44 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

5h 14m1 stop Denver Intl

2:53 pm - 7:48 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$258Multiple Airlines

Fri, Sep 11 - Fri, Sep 18

11:29 am - 9:35 amDSM Des Moines-DFW Dallas/Fort Worth

22h 06m1 stop Denver Intl

2:48 pm - 7:33 pmDFW Dallas/Fort Worth-DSM Des Moines

4h 45m1 stop Denver Intl

$280Frontier

Sun, Sep 13 - Fri, Sep 25

11:29 am - 12:59 amDSM Des Moines-MCO Orlando

12h 30m1 stop Denver Intl

5:25 pm - 7:33 pmMCO Orlando-DSM Des Moines

27h 08m1 stop Denver Intl

$280Frontier

Thu, Sep 10 - Sun, Sep 13

9:56 pm - 11:06 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 10mnonstop

9:45 am - 7:33 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

7h 48m1 stop Denver Intl

$298Multiple Airlines

Sun, Sep 13 - Mon, Sep 14

9:31 pm - 10:41 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 10mnonstop

4:11 pm - 9:06 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$334Allegiant Air

Fri, Sep 11 - Sun, Sep 13

7:20 am - 7:40 pmDSM Des Moines-LGA New York LaGuardia

11h 20m2 stops Denver Intl Lambert-St Louis

6:00 am - 11:25 amLGA New York LaGuardia-DSM Des Moines

6h 25m1 stop Chicago Midway

$391Southwest

Sat, Sep 12 - Thu, Sep 24

7:20 am - 8:10 pmDSM Des Moines-LGA New York LaGuardia

11h 50m1 stop Denver Intl

6:00 am - 11:25 amLGA New York LaGuardia-DSM Des Moines

6h 25m1 stop Chicago Midway

$391Southwest

Sat, Sep 12 - Thu, Sep 24

4:14 pm - 6:20 pmDSM Des Moines-DFW Dallas/Fort Worth

2h 06mnonstop

9:15 pm - 11:12 pmDFW Dallas/Fort Worth-DSM Des Moines

1h 57mnonstop

$423American Airlines

Wed, Sep 9 - Sat, Sep 12

6:41 am - 10:32 amDSM Des Moines-LAS Las Vegas Harry Reid Intl

5h 51m1 stop Dallas/Fort Worth

9:00 am - 5:52 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

6h 52m1 stop Dallas/Fort Worth

$431American Airlines

Wed, Sep 9 - Sat, Sep 12

Cheapest international flights from Des Moines

Enter your travel dates to find the best prices.

8:43 am - 11:54 pmDSM Des Moines-SJU San Juan Luis Munoz Marin Intl

14h 11m1 stop Philadelphia

6:15 am - 2:42 pmSJU San Juan Luis Munoz Marin Intl-DSM Des Moines

9h 27m1 stop Philadelphia

$246Multiple Airlines

Sun, Oct 18 - Thu, Oct 22

8:10 am - 12:01 amDSM Des Moines-SJU San Juan Luis Munoz Marin Intl

14h 51m1 stop Philadelphia

6:15 am - 2:42 pmSJU San Juan Luis Munoz Marin Intl-DSM Des Moines

9h 27m1 stop Philadelphia

$247Multiple Airlines

Thu, Oct 1 - Thu, Oct 8

8:43 am - 11:54 pmDSM Des Moines-SJU San Juan Luis Munoz Marin Intl

14h 11m1 stop Philadelphia

6:15 am - 2:42 pmSJU San Juan Luis Munoz Marin Intl-DSM Des Moines

9h 27m1 stop Philadelphia

$269Multiple Airlines

Thu, Oct 15 - Thu, Oct 22

8:43 am - 2:09 amDSM Des Moines-SJU San Juan Luis Munoz Marin Intl

16h 26m2 stops Philadelphia Miami

12:59 am - 2:42 pmSJU San Juan Luis Munoz Marin Intl-DSM Des Moines

14h 43m1 stop Philadelphia

$291Multiple Airlines

Sun, Oct 18 - Wed, Oct 21

1:58 pm - 12:01 amDSM Des Moines-SJU San Juan Luis Munoz Marin Intl

9h 03m1 stop Philadelphia

12:59 am - 7:57 pmSJU San Juan Luis Munoz Marin Intl-DSM Des Moines

19h 58m1 stop Philadelphia

$329Multiple Airlines

Sun, Sep 20 - Wed, Sep 23

8:10 am - 2:13 amDSM Des Moines-SJU San Juan Luis Munoz Marin Intl

17h 03m2 stops Philadelphia Miami

6:15 am - 2:42 pmSJU San Juan Luis Munoz Marin Intl-DSM Des Moines

9h 27m1 stop Philadelphia

$332Multiple Airlines

Thu, Oct 1 - Thu, Oct 8

1:58 pm - 12:01 amDSM Des Moines-SJU San Juan Luis Munoz Marin Intl

9h 03m1 stop Philadelphia

5:27 pm - 12:39 pmSJU San Juan Luis Munoz Marin Intl-DSM Des Moines

20h 12m1 stop Philadelphia

$342Multiple Airlines

Thu, Sep 24 - Sat, Oct 3

1:58 pm - 5:48 pmDSM Des Moines-SJU San Juan Luis Munoz Marin Intl

26h 50m1 stop Philadelphia

8:45 am - 9:02 amSJU San Juan Luis Munoz Marin Intl-DSM Des Moines

25h 17m1 stop Fort Lauderdale

$350Multiple Airlines

Thu, Sep 24 - Wed, Sep 30

1:58 pm - 4:06 pmDSM Des Moines-SJU San Juan Luis Munoz Marin Intl

49h 08m2 stops Philadelphia Atlanta Hartsfield-Jackson

8:45 am - 9:02 amSJU San Juan Luis Munoz Marin Intl-DSM Des Moines

25h 17m1 stop Fort Lauderdale

$360Multiple Airlines

Thu, Sep 24 - Wed, Sep 30

1:58 pm - 5:48 pmDSM Des Moines-SJU San Juan Luis Munoz Marin Intl

26h 50m1 stop Philadelphia

12:59 am - 2:10 pmSJU San Juan Luis Munoz Marin Intl-DSM Des Moines

14h 11m1 stop Philadelphia

$370Multiple Airlines

Thu, Sep 24 - Wed, Sep 30

Cheapest domestic flights from Des Moines

Enter your travel dates to find the best prices.

10:09 pm - 11:23 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 14mnonstop

5:58 pm - 10:50 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 52mnonstop

$101Allegiant Air

Sun, Oct 18 - Thu, Oct 22

9:31 pm - 10:41 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 10mnonstop

4:11 pm - 9:06 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$112Allegiant Air

Mon, Sep 21 - Thu, Sep 24

9:11 pm - 10:25 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 14mnonstop

9:00 am - 1:55 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$118Allegiant Air

Mon, Nov 2 - Wed, Nov 4

1:00 pm - 2:14 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 14mnonstop

3:50 pm - 8:41 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 51mnonstop

$122Allegiant Air

Sun, Nov 15 - Fri, Nov 20

1:00 pm - 2:14 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 14mnonstop

3:50 pm - 8:41 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 51mnonstop

$123Allegiant Air

Sun, Nov 15 - Fri, Nov 20

9:11 pm - 10:25 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 14mnonstop

9:00 am - 1:55 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$127Allegiant Air

Mon, Nov 2 - Wed, Nov 4

9:31 pm - 10:41 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 10mnonstop

4:11 pm - 9:06 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$128Allegiant Air

Mon, Sep 21 - Thu, Sep 24

2:42 pm - 3:56 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 14mnonstop

6:05 am - 10:57 amLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 52mnonstop

$131Allegiant Air

Wed, Sep 30 - Fri, Oct 2

9:11 pm - 10:25 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 14mnonstop

9:00 am - 1:55 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$137Allegiant Air

Mon, Nov 2 - Wed, Nov 4

9:31 pm - 10:41 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 10mnonstop

2:34 pm - 7:26 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 52mnonstop

$139Allegiant Air

Mon, Sep 28 - Thu, Oct 1

Flights from Des Moines - Travel Insights & Trends

Get data-powered insights and trends into flights from Des Moines to help you craft the best travel plan.

Prices

Other information

What are the most popular domestic flights out of Des Moines?

According to searches, the most popular destinations for domestic flights from Des Moines among momondo users are Chicago, New York, Chicago, Los Angeles and New York.

What are the cheapest cities to fly to from Des Moines?

The cheapest city to fly to from Des Moines currently is Philadelphia at $43. The next cheapest destinations are Las Vegas, Sarasota, Boston, Houston and Tampa.

Frequently asked questions regarding flights from Des Moines

Which airlines are currently offering the cheapest flights from Des Moines?

Our data suggests that currently, the cheapest flights from Des Moines are being offered by American Airlines, JetBlue, and Allegiant Air. For example, American Airlines flights from Des Moines to Jacksonville, start at $56, JetBlue flights from Des Moines to Denver cost around $59, and Allegiant Air flights from Des Moines to Burbank are around $126.

What is the cheapest flight available from Des Moines?

Currently, the cheapest flight from Des Moines found by our users is for $43 to Philadelphia. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $288 to travel from Des Moines to Philadelphia.

Which destinations have the most frequent flights from Des Moines?

Chicago, Chicago O'Hare Intl Airport and Denver are currently the destinations served most frequently from Des Moines, with 32, 31 and 11 flights per day on average, respectively.

Which airlines can you fly with from Des Moines?

Airlines including American Airlines, United Airlines and Delta frequently fly from Des Moines. You can view other airlines by performing a quick search in the form above.

What is the cheapest first class flight from Des Moines?

If you are looking for a cheap first class flight, consider flights to Chicago O'Hare Intl Airport, for which the starting price of a first class seat can be as low as $560.

When did momondo last update prices for flights from Des Moines Airport?

Prices for flights from Des Moines Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport?

There are 29 operators available for flights from Des Moines Airport as of September 2026.

How old do you have to be to fly from Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.