Cheap flights from Des Moines (DSM) from $79

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Fly to

Route

Depart

Return

Price

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

Sun 2/15

7:27 pm-8:30 pm

Nonstop2h 03m

$29

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

Wed 3/18

8:21 pm-9:26 pm

Nonstop2h 05m

$32

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

Fri 3/6

8:21 pm-9:26 pm

Nonstop2h 05m

$33

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

Mon 3/2

7:17 pm-8:20 pm

Nonstop2h 03m

$34

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

Fri 2/20

7:17 pm-8:20 pm

Nonstop2h 03m

$39

Des MoinesLas Vegas

DSM - LAS

DSMLAS

Des Moines

Sun 2/15

7:30 am-8:59 am

Nonstop3h 29m

$54

Des MoinesLas Vegas

DSM - LAS

DSMLAS

Des Moines

Sun 2/15

7:30 am-8:59 am

Nonstop3h 29m

$56

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 2/3

8:00 am-3:05 pm

1 stop6h 05m

$119

Des MoinesHouston

DSM - HOU

DSMHOU

Des Moines

Fri 2/27

7:27 pm-11:58 pm

1 stop4h 31m

$230

Des MoinesHouston

DSM - HOU

DSMHOU

Des Moines

Fri 2/27

10:36 am-10:28 pm

2 stops11h 52m

$635

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

Where can I directly fly to from Des Moines?

Currently, 14 destinations can be reached directly via flights from Des Moines.

Flights from Des Moines to

Austin

from$58

Flights from Des Moines to

Boston

from$48

Flights from Des Moines to

Denver

from$116

Flights from Des Moines to

Fort Lauderdale

from$66

Flights from Des Moines to

Fort Myers

from$88

Flights from Des Moines to

Jacksonville

from$277

Flights from Des Moines to

Las Vegas

from$61

Flights from Des Moines to

Los Angeles

from$159

Flights from Des Moines to

Nashville

from$85

Flights from Des Moines to

Portland

from$291

Flights from Des Moines to

Punta Gorda

from$119

Flights from Des Moines to

Santa Ana, California

from$108

Flights from Des Moines to

Sarasota

from$174

Flights from Des Moines to

Tampa

from$190

Find the cheapest flights from Des Moines

One-way

Last minute

International

Domestic

Cheap one-way flights from Des Moines

Enter your travel dates to find the best prices.

7:27 pm - 8:30 pm

DSM

DEN

2h 03mnonstop

$29Frontier

Sun, Feb 15

8:21 pm - 9:26 pm

DSM

DEN

2h 05mnonstop

$32Frontier

Wed, Mar 18

8:21 pm - 9:26 pm

DSM

DEN

2h 05mnonstop

$33Frontier

Fri, Mar 6

7:17 pm - 8:20 pm

DSM

DEN

2h 03mnonstop

$34Frontier

Mon, Mar 2

7:17 pm - 8:20 pm

DSM

DEN

2h 03mnonstop

$39Frontier

Fri, Feb 20

7:30 am - 8:59 am

DSM

LAS

3h 29mnonstop

$54Allegiant Air

Sun, Feb 15

7:30 am - 8:59 am

DSM

LAS

3h 29mnonstop

$56Allegiant Air

Sun, Feb 15

8:00 am - 3:05 pm

DSM

MIA

6h 05m

1 stop

$119United Airlines

Tue, Feb 3

7:27 pm - 11:58 pm

DSM

HOU

4h 31m

1 stop

$230American Airlines

Fri, Feb 27

10:36 am - 10:28 pm

DSM

HOU

11h 52m

2 stops

$635Delta

Fri, Feb 27

Flights from Des Moines - Travel Insights & Trends

Get data-powered insights and trends into flights from Des Moines to help you craft the best travel plan.

Prices

Other information

What are the most popular domestic flights out of Des Moines?

Departing from Des Moines, the top domestic flight destinations, based on momondo users' searches, include Los Angeles, Boston, Chicago, Phoenix, and Los Angeles.

What are the cheapest cities to fly to from Des Moines?

The cheapest city to fly to from Des Moines currently is Boston at $48. The next cheapest destinations are Orlando, Austin, Phoenix, Las Vegas and Fort Lauderdale.

Frequently asked questions regarding flights from Des Moines

Which airlines are currently offering the cheapest flights from Des Moines?

Our data suggests that currently, the cheapest flights from Des Moines are being offered by American Airlines, Frontier, and Allegiant Air. For example, American Airlines flights from Des Moines to Houston Hobby Airport, start at $54, Frontier flights from Des Moines to Denver cost around $62, and Allegiant Air flights from Des Moines to Orlando Sanford Intl Airport are around $91.

What is the cheapest flight available from Des Moines?

Currently, the cheapest flight from Des Moines found by our users is for $48 to Boston. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $164 to travel from Des Moines to Boston.

Which destinations have the most frequent flights from Des Moines?

Chicago O'Hare Intl Airport, Chicago and Dallas/Fort Worth Airport are currently the destinations served most frequently from Des Moines, with 29, 29 and 16 flights per day on average, respectively.

Which airlines can you fly with from Des Moines?

Airlines including American Airlines, Delta and United Airlines frequently fly from Des Moines. You can view other airlines by performing a quick search in the form above.

What is the cheapest first class flight from Des Moines?

If you are looking for a cheap first class flight, consider flights to Chicago O'Hare Intl Airport, for which the starting price of a first class seat can be as low as $416.

When did momondo last update prices for flights from Des Moines Airport?

Prices for flights from Des Moines Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport?

There are 25 operators available for flights from Des Moines Airport as of January 2026.

How old do you have to be to fly from Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.