Cheap flights from Des Moines (DSM) from $80

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Fly to

Route

Depart

Return

Price

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

lun. 1/12

8:17 pm-9:29 pm

Nonstop2h 12m

$40

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

lun. 1/5

8:29 pm-9:41 pm

Nonstop2h 12m

$60

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

vie. 1/9

8:17 pm-9:29 pm

Nonstop2h 12m

$61

Des MoinesLas Vegas

DSM - LAS

DSMLAS

Des Moines

dom. 2/8

8:30 am-9:49 am

Nonstop3h 19m

$70

Des MoinesLas Vegas

DSM - LAS

DSMLAS

Des Moines

dom. 1/25

8:30 am-9:49 am

Nonstop3h 19m

$71

Des MoinesHouston

DSM - IAH

DSMIAH

Des Moines

mié. 1/7

8:00 am-1:40 pm

1 stop5h 40m

$115

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

sáb. 1/10

1:35 pm-2:53 pm

Nonstop2h 18m

$123

Des MoinesHouston

DSM - HOU

DSMHOU

Des Moines

sáb. 1/24

5:51 pm-10:46 pm

1 stop4h 55m

$150

Des MoinesHouston

DSM - IAH

DSMIAH

Des Moines

mié. 1/7

12:04 pm-9:13 pm

2 stops9h 09m

$239

Des MoinesHouston

DSM - HOU

DSMHOU

Des Moines

dom. 1/25

6:24 am-4:10 pm

2 stops9h 46m

$245

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

Where can I directly fly to from Des Moines?

Currently, 15 destinations can be reached directly via flights from Des Moines.

Flights from Des Moines to

Austin

from$53

Flights from Des Moines to

Boston

from$48

Flights from Des Moines to

Denver

from$95

Flights from Des Moines to

Fort Lauderdale

from$60

Flights from Des Moines to

Fort Myers

from$90

Flights from Des Moines to

Las Vegas

from$55

Flights from Des Moines to

Los Angeles

from$122

Flights from Des Moines to

Miami

from$235

Flights from Des Moines to

Minneapolis

from$117

Flights from Des Moines to

Nashville

from$46

Flights from Des Moines to

Portland

from$156

Flights from Des Moines to

Punta Gorda

from$199

Flights from Des Moines to

Santa Ana, California

from$127

Flights from Des Moines to

Sarasota

from$90

Flights from Des Moines to

Tampa

from$178

Find the cheapest flights from Des Moines

One-way

Last minute

International

Domestic

Cheap one-way flights from Des Moines

Enter your travel dates to find the best prices.

8:17 pm - 9:29 pm

DSM

DEN

2h 12mnonstop

$40Frontier

lun., ene. 12

8:29 pm - 9:41 pm

DSM

DEN

2h 12mnonstop

$60Frontier

lun., ene. 5

8:17 pm - 9:29 pm

DSM

DEN

2h 12mnonstop

$61Frontier

vie., ene. 9

8:30 am - 9:49 am

DSM

LAS

3h 19mnonstop

$70Allegiant Air

dom., feb. 8

8:30 am - 9:49 am

DSM

LAS

3h 19mnonstop

$71Allegiant Air

dom., ene. 25

8:00 am - 1:40 pm

DSM

IAH

5h 40m1 stop

$115United Airlines

mié., ene. 7

1:35 pm - 2:53 pm

DSM

DEN

2h 18mnonstop

$123United Airlines

sáb., ene. 10

5:51 pm - 10:46 pm

DSM

HOU

4h 55m1 stop

$150American Airlines

sáb., ene. 24

12:04 pm - 9:13 pm

DSM

IAH

9h 09m2 stops

$239Delta

mié., ene. 7

6:24 am - 4:10 pm

DSM

HOU

9h 46m2 stops

$245Delta

dom., ene. 25

Flights from Des Moines - Travel Insights & Trends

Get data-powered insights and trends into flights from Des Moines to help you craft the best travel plan.

Prices

Other information

What are the most popular domestic flights out of Des Moines?

According to searches, the most popular destinations for domestic flights from Des Moines among momondo users are Boston, New York, Phoenix, Los Angeles and Los Angeles.

What are the cheapest cities to fly to from Des Moines?

The cheapest city to fly to from Des Moines currently is Nashville at $46. The next cheapest destinations are Boston, Orlando, Austin, Las Vegas and Fort Lauderdale.

Frequently asked questions regarding flights from Des Moines

Which airlines are currently offering the cheapest flights from Des Moines?

Our data suggests that currently, the cheapest flights from Des Moines are being offered by American Airlines, Frontier, and Allegiant Air. For example, American Airlines flights from Des Moines to Houston Hobby Airport, start at $54, Frontier flights from Des Moines to Denver cost around $61, and Allegiant Air flights from Des Moines to Orlando Sanford Intl Airport are around $88.

What is the cheapest flight available from Des Moines?

Currently, the cheapest flight from Des Moines found by our users is for $46 to Nashville. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $131 to travel from Des Moines to Nashville.

Which destinations have the most frequent flights from Des Moines?

Chicago, Chicago O'Hare Intl Airport and Atlanta are currently the destinations served most frequently from Des Moines, with 38, 38 and 18 flights per day on average, respectively.

Which airlines can you fly with from Des Moines?

Airlines including American Airlines, United Airlines and Delta frequently fly from Des Moines. You can view other airlines by performing a quick search in the form above.

When did momondo last update prices for flights from Des Moines Airport?

Prices for flights from Des Moines Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport?

There are 26 operators available for flights from Des Moines Airport as of December 2025.

How old do you have to be to fly from Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.