Cheap flights from Des Moines (DSM) from $87

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Fly to

Route

Depart

Return

Price

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

lun. 12/22

8:29 pm-9:41 pm

Nonstop2h 12m

$19

Des MoinesDenver

DSM - DEN

DSMDEN

Des Moines

vie. 12/19

8:29 pm-9:41 pm

Nonstop2h 12m

$20

Des MoinesLas Vegas

DSM - LAS

DSMLAS

Des Moines

vie. 1/23

8:30 am-9:49 am

Nonstop3h 19m

$55

Des MoinesLas Vegas

DSM - LAS

DSMLAS

Des Moines

lun. 12/15

7:28 pm-8:44 pm

Nonstop3h 16m

$60

Des MoinesOrlando

DSM - MCO

DSMMCO

Des Moines

lun. 2/9

11:09 am-12:20 pm

1 stop24h 11m

$94

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

vie. 12/12

7:58 pm-10:24 pm

2 stops28h 26m

$95

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

mié. 12/10

8:20 am-4:00 pm

1 stop6h 40m

$100

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

mar. 12/9

11:01 am-2:59 pm

1 stop3h 58m

$105

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

sáb. 12/13

6:50 am-11:43 am

1 stop4h 53m

$107

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

mié. 12/10

6:15 am-12:15 pm

2 stops6h 00m

$110

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

Where can I directly fly to from Des Moines?

Currently, 15 destinations can be reached directly via flights from Des Moines.

Flights from Des Moines to

Austin

from$75

Flights from Des Moines to

Boston

from$48

Flights from Des Moines to

Denver

from$78

Flights from Des Moines to

Fort Lauderdale

from$66

Flights from Des Moines to

Fort Myers

from$111

Flights from Des Moines to

Jacksonville

from$42

Flights from Des Moines to

Las Vegas

from$88

Flights from Des Moines to

Los Angeles

from$153

Flights from Des Moines to

Miami

from$146

Flights from Des Moines to

Nashville

from$52

Flights from Des Moines to

Portland

from$156

Flights from Des Moines to

Punta Gorda

from$88

Flights from Des Moines to

Santa Ana, California

from$117

Flights from Des Moines to

Sarasota

from$116

Flights from Des Moines to

Tampa

from$85

Find the cheapest flights from Des Moines

One-way

Last minute

International

Domestic

Cheap one-way flights from Des Moines

Enter your travel dates to find the best prices.

8:29 pm - 9:41 pmDSM-DEN

2h 12mnonstop

$19Frontier

Find Deal

lun., dic. 22

8:29 pm - 9:41 pmDSM-DEN

2h 12mnonstop

$20Frontier

Find Deal

vie., dic. 19

8:30 am - 9:49 amDSM-LAS

3h 19mnonstop

$55Allegiant Air

Find Deal

vie., ene. 23

7:28 pm - 8:44 pmDSM-LAS

3h 16mnonstop

$60Allegiant Air

Find Deal

lun., dic. 15

11:09 am - 12:20 pmDSM-MCO

24h 11m1 stop

$94Multiple Airlines

Find Deal

lun., feb. 9

7:58 pm - 10:24 pmDSM-LAX

28h 26m2 stops

$95Multiple Airlines

Find Deal

vie., dic. 12

8:20 am - 4:00 pmDSM-MIA

6h 40m1 stop

$100Southwest

Find Deal

mié., dic. 10

11:01 am - 2:59 pmDSM-ORD

3h 58m1 stop

$105Delta

Find Deal

mar., dic. 9

6:50 am - 11:43 amDSM-ORD

4h 53m1 stop

$107Delta

Find Deal

sáb., dic. 13

6:15 am - 12:15 pmDSM-ORD

6h 00m2 stops

$110Southwest

Find Deal

mié., dic. 10

Flights from Des Moines - Travel Insights & Trends

Get data-powered insights and trends into flights from Des Moines to help you craft the best travel plan.

Prices

Other information

What are the most popular domestic flights out of Des Moines?

From Des Moines, you can take domestic flights to many cities. Searches reveal that momondo users prefer flights to Jacksonville, New York, Phoenix, Los Angeles, and Portland the most.

What are the cheapest cities to fly to from Des Moines?

The cheapest city to fly to from Des Moines currently is Jacksonville at $42. The next cheapest destinations are Boston, Nashville, New York, Orlando and Fort Lauderdale.

Frequently asked questions regarding flights from Des Moines

Which airlines are currently offering the cheapest flights from Des Moines?

Our data suggests that currently, the cheapest flights from Des Moines are being offered by American Airlines, Frontier, and Allegiant Air. For example, American Airlines flights from Des Moines to Houston Hobby Airport, start at $58, Frontier flights from Des Moines to Denver cost around $61, and Allegiant Air flights from Des Moines to Orlando Sanford Intl Airport are around $86.

What is the cheapest flight available from Des Moines?

Currently, the cheapest flight from Des Moines found by our users is for $42 to Jacksonville. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $94 to travel from Des Moines to Jacksonville.

Which destinations have the most frequent flights from Des Moines?

Chicago, Chicago O'Hare Intl Airport and Atlanta are currently the destinations served most frequently from Des Moines, with 37, 37 and 19 flights per day on average, respectively.

Which airlines can you fly with from Des Moines?

Airlines including American Airlines, United Airlines and Delta frequently fly from Des Moines. You can view other airlines by performing a quick search in the form above.

What is the cheapest first class flight from Des Moines?

If you are looking for a cheap first class flight, consider flights to Chicago O'Hare Intl Airport, for which the starting price of a first class seat can be as low as $484.

When did momondo last update prices for flights from Des Moines Airport?

Prices for flights from Des Moines Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport?

There are 26 operators available for flights from Des Moines Airport as of November 2025.

How old do you have to be to fly from Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.