Cheap flights from Des Moines (DSM) from $54

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Fly to

Route

Depart

Return

Price

Cheapest one-way

Des MoinesLas Vegas

DSM Des Moines - LAS Las Vegas Harry Reid Intl

DSMLAS

Des Moines

Mon 11/16

8:04 pm-9:18 pm

Nonstop3h 14m

$54

Des MoinesLas Vegas

DSM Des Moines - LAS Las Vegas Harry Reid Intl

DSMLAS

Des Moines

Sun 1/10

10:07 pm-11:24 pm

Nonstop3h 17m

$59

Des MoinesDenver

DSM Des Moines - DEN Denver Intl

DSMDEN

Des Moines

Thu 1/14

7:43 pm-8:45 pm

Nonstop2h 02m

$80

Des MoinesDenver

DSM Des Moines - DEN Denver Intl

DSMDEN

Des Moines

Thu 11/26

8:28 pm-9:34 pm

Nonstop2h 06m

$83

Des MoinesDenver

DSM Des Moines - DEN Denver Intl

DSMDEN

Des Moines

Mon 12/14

10:40 am-3:25 pm

1 stop29h 45m

$90

Des MoinesOrlando

DSM Des Moines - MCO Orlando

DSMMCO

Des Moines

Mon 12/7

2:50 pm-1:47 pm

2 stops21h 57m

$102

Des MoinesLos Angeles

DSM Des Moines - LAX Los Angeles

DSMLAX

Des Moines

Mon 1/25

7:49 pm-9:59 pm

Nonstop4h 10m

$114

Des MoinesLos Angeles

DSM Des Moines - LAX Los Angeles

DSMLAX

Des Moines

Sat 1/16

7:49 pm-9:59 pm

Nonstop4h 10m

$119

Des MoinesChicago

DSM Des Moines - ORD Chicago O'Hare Intl

DSMORD

Des Moines

Fri 12/18

5:00 am-6:47 am

Nonstop1h 47m

$119

Quickest one-way

Des MoinesChicago

DSM Des Moines - ORD Chicago O'Hare Intl

DSMORD

Des Moines

Fri 11/27

8:00 am-9:40 am

Nonstop1h 40m

$119

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

Where can I directly fly to from Des Moines?

Currently, 14 destinations can be reached directly via flights from Des Moines.

Flights from Des Moines to

Austin

from$62

Flights from Des Moines to

Boston

from$63

Flights from Des Moines to

Charlotte

from$164

Flights from Des Moines to

Fort Lauderdale

from$79

Flights from Des Moines to

Fort Myers

from$118

Flights from Des Moines to

Jacksonville

from$100

Flights from Des Moines to

Las Vegas

from$133

Flights from Des Moines to

Los Angeles

from$113

Flights from Des Moines to

Nashville

from$50

Flights from Des Moines to

Philadelphia

from$34

Flights from Des Moines to

Punta Gorda

from$165

Flights from Des Moines to

Santa Ana, California

from$100

Flights from Des Moines to

Sarasota

from$85

Flights from Des Moines to

Tampa

from$128

Find the cheapest flights from Des Moines

One-way

Last minute

International

Domestic

Cheap one-way flights from Des Moines

Enter your travel dates to find the best prices.

8:04 pm - 9:18 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 14mnonstop

$54Allegiant Air

Mon, Nov 16

10:07 pm - 11:24 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 17mnonstop

$59Allegiant Air

Sun, Jan 10

7:43 pm - 8:45 pmDSM Des Moines-DEN Denver Intl

2h 02mnonstop

$80Frontier

Thu, Jan 14

8:28 pm - 9:34 pmDSM Des Moines-DEN Denver Intl

2h 06mnonstop

$83Frontier

Thu, Nov 26

10:40 am - 3:25 pmDSM Des Moines-DEN Denver Intl

29h 45m1 stop Nashville Intl

$90Multiple Airlines

Mon, Dec 14

2:50 pm - 1:47 pmDSM Des Moines-MCO Orlando

21h 57m2 stops Tampa St. Petersburg Atlanta Hartsfield-Jackson

$102Multiple Airlines

Mon, Dec 7

7:49 pm - 9:59 pmDSM Des Moines-LAX Los Angeles

4h 10mnonstop

$114American Airlines

Mon, Jan 25

7:49 pm - 9:59 pmDSM Des Moines-LAX Los Angeles

4h 10mnonstop

$119American Airlines

Sat, Jan 16

5:00 am - 6:47 amDSM Des Moines-ORD Chicago O'Hare Intl

1h 47mnonstop

$119United Airlines

Fri, Dec 18

8:00 am - 9:40 amDSM Des Moines-ORD Chicago O'Hare Intl

1h 40mnonstop

$119United Airlines

Fri, Nov 27

Last-minute flight deals from Des Moines

Enter your travel dates to find the best prices.

2:45 pm - 3:59 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 14mnonstop

3:09 pm - 8:04 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$178Allegiant Air

Wed, Nov 11 - Thu, Nov 12

8:04 pm - 9:18 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 14mnonstop

3:09 pm - 8:04 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$179Allegiant Air

Mon, Nov 9 - Thu, Nov 12

10:25 pm - 11:39 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 14mnonstop

11:56 am - 7:35 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

5h 39m1 stop Denver Intl

$281Multiple Airlines

Fri, Nov 13 - Mon, Nov 16

10:25 pm - 11:39 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 14mnonstop

11:56 am - 7:35 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

5h 39m1 stop Denver Intl

$286Multiple Airlines

Fri, Nov 13 - Mon, Nov 16

8:30 pm - 9:04 amDSM Des Moines-PHX Phoenix Sky Harbor Intl

13h 34m1 stop Denver Intl

10:00 am - 7:33 pmPHX Phoenix Sky Harbor Intl-DSM Des Moines

8h 33m1 stop Denver Intl

$300Frontier

Fri, Nov 13 - Thu, Nov 26

8:30 pm - 4:18 pmDSM Des Moines-MCO Orlando

18h 48m1 stop Denver Intl

8:28 pm - 7:33 pmMCO Orlando-DSM Des Moines

24h 05m1 stop Denver Intl

$310Frontier

Fri, Nov 13 - Sat, Nov 21

8:05 pm - 10:00 pmDSM Des Moines-LAX Los Angeles

3h 55mnonstop

6:00 am - 2:35 pmLAX Los Angeles-DSM Des Moines

6h 35m1 stop Dallas/Fort Worth

$454American Airlines

Fri, Nov 13 - Fri, Nov 27

5:09 pm - 8:48 pmDSM Des Moines-LAX Los Angeles

5h 39m1 stop Denver Intl

5:00 am - 12:31 pmLAX Los Angeles-DSM Des Moines

5h 31m1 stop Denver Intl

$458United Airlines

Fri, Nov 13 - Fri, Nov 27

7:26 pm - 9:13 pmDSM Des Moines-ORD Chicago O'Hare Intl

1h 47mnonstop

7:12 am - 8:53 amORD Chicago O'Hare Intl-DSM Des Moines

1h 41mnonstop

$462American Airlines

Mon, Nov 9 - Thu, Dec 10

1:27 pm - 6:42 pmDSM Des Moines-DFW Dallas/Fort Worth

5h 15m1 stop Denver Intl

5:45 am - 12:31 pmDFW Dallas/Fort Worth-DSM Des Moines

6h 46m1 stop Denver Intl

$501United Airlines

Wed, Nov 11 - Sat, Nov 14

Cheapest international flights from Des Moines

Enter your travel dates to find the best prices.

12:00 pm - 9:30 amDSM Des Moines-MAD Madrid Barajas

14h 30m1 stop Chicago O'Hare Intl

1:35 pm - 11:49 pmMAD Madrid Barajas-DSM Des Moines

17h 14m1 stop Chicago O'Hare Intl

$712Iberia

Tue, Apr 27 - Tue, May 4

6:15 am - 9:30 amDSM Des Moines-MAD Madrid Barajas

20h 15m2 stops Chicago O'Hare Intl Newark

12:50 pm - 2:12 pmMAD Madrid Barajas-DSM Des Moines

31h 22m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$714United Airlines

Tue, Mar 9 - Tue, Mar 16

6:18 pm - 8:00 amDSM Des Moines-MAD Madrid Barajas

30h 42m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl

1:25 pm - 6:43 pmMAD Madrid Barajas-DSM Des Moines

36h 18m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$717Air Canada

Sun, Feb 14 - Thu, Feb 18

6:45 pm - 2:05 amDSM Des Moines-IST Istanbul

23h 20m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

3:45 am - 11:01 pmIST Istanbul-DSM Des Moines

27h 16m2 stops Munich Franz Josef Strauss Chicago O'Hare Intl

$748Lufthansa

Tue, Apr 6 - Mon, Apr 19

1:05 pm - 2:10 pmDSM Des Moines-CPH Kastrup Copenhagen

18h 05m2 stops Chicago O'Hare Intl Zurich

11:35 am - 2:12 pmCPH Kastrup Copenhagen-DSM Des Moines

33h 37m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$750United Airlines

Mon, Mar 1 - Wed, Mar 3

12:52 pm - 6:10 pmDSM Des Moines-IST Istanbul

20h 18m2 stops Chicago O'Hare Intl Frankfurt am Main

6:30 am - 9:23 pmIST Istanbul-DSM Des Moines

23h 53m2 stops Frankfurt am Main Chicago O'Hare Intl

$759Lufthansa

Mon, Feb 1 - Fri, Feb 5

2:02 pm - 5:35 pmDSM Des Moines-IST Istanbul

18h 33m2 stops Chicago O'Hare Intl London Heathrow

6:50 pm - 7:04 pmIST Istanbul-DSM Des Moines

33h 14m2 stops London Heathrow Chicago O'Hare Intl

$772British Airways

Mon, Feb 15 - Wed, Feb 24

3:15 pm - 2:05 pmDSM Des Moines-CPH Kastrup Copenhagen

15h 50m2 stops Chicago O'Hare Intl Zurich

12:45 pm - 12:22 pmCPH Kastrup Copenhagen-DSM Des Moines

30h 37m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$788United Airlines

Tue, Apr 13 - Tue, Apr 20

1:05 pm - 2:05 pmDSM Des Moines-CPH Kastrup Copenhagen

18h 00m2 stops Chicago O'Hare Intl Zurich

12:45 pm - 8:32 pmCPH Kastrup Copenhagen-DSM Des Moines

38h 47m2 stops Toronto Pearson Intl Denver Intl

$789United Airlines

Tue, Apr 13 - Tue, Apr 20

9:45 am - 6:25 pmDSM Des Moines-HND Tokyo Haneda

17h 40m1 stop Dallas/Fort Worth

1:05 pm - 7:10 pmHND Tokyo Haneda-DSM Des Moines

21h 05m1 stop Los Angeles

$941American Airlines

Tue, Dec 1 - Tue, Dec 15

Cheapest domestic flights from Des Moines

Enter your travel dates to find the best prices.

9:18 pm - 10:39 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 21mnonstop

4:28 pm - 9:23 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$147Allegiant Air

Mon, Dec 14 - Thu, Dec 31

3:15 pm - 4:36 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 21mnonstop

4:28 pm - 9:23 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$148Allegiant Air

Sun, Dec 13 - Thu, Dec 17

7:30 am - 8:47 amDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 17mnonstop

9:37 am - 2:34 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 57mnonstop

$151Allegiant Air

Mon, Feb 1 - Fri, Feb 5

9:35 pm - 10:52 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 17mnonstop

4:28 pm - 9:23 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 55mnonstop

$167Allegiant Air

Mon, Dec 21 - Thu, Dec 24

10:00 am - 11:21 amDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 21mnonstop

6:19 pm - 11:10 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 51mnonstop

$171Allegiant Air

Sun, Feb 7 - Thu, Feb 11

2:10 pm - 3:37 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 27mnonstop

4:27 pm - 9:18 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 51mnonstop

$174Allegiant Air

Mon, Feb 22 - Fri, Feb 26

4:02 pm - 5:29 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 27mnonstop

6:19 pm - 11:10 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

2h 51mnonstop

$177Allegiant Air

Sun, Feb 21 - Thu, Feb 25

8:28 pm - 11:52 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

5h 24m1 stop Denver Intl

5:26 pm - 10:26 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

3h 00mnonstop

$179Multiple Airlines

Thu, Nov 26 - Thu, Dec 3

9:18 pm - 10:39 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

3h 21mnonstop

9:13 pm - 7:31 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

20h 18m1 stop Denver Intl

$181Multiple Airlines

Mon, Dec 14 - Wed, Dec 30

8:28 pm - 11:52 pmDSM Des Moines-LAS Las Vegas Harry Reid Intl

5h 24m1 stop Denver Intl

5:26 pm - 10:26 pmLAS Las Vegas Harry Reid Intl-DSM Des Moines

3h 00mnonstop

$183Multiple Airlines

Thu, Nov 26 - Thu, Dec 3

Flights from Des Moines - Travel Insights & Trends

Get data-powered insights and trends into flights from Des Moines to help you craft the best travel plan.

Prices

Other information

What are the most popular domestic flights out of Des Moines?

According to searches, the most popular destinations for domestic flights from Des Moines among momondo users are Boston, Fort Lauderdale, Denver, Phoenix and Chicago.

What are the cheapest cities to fly to from Des Moines?

The cheapest city to fly to from Des Moines currently is Philadelphia at $34. The next cheapest destinations are Nashville, Austin, Boston, Fort Lauderdale and Sarasota.

Frequently asked questions regarding flights from Des Moines

Which airlines are currently offering the cheapest flights from Des Moines?

Our data suggests that currently, the cheapest flights from Des Moines are being offered by Frontier, American Airlines, and Allegiant Air. For example, Frontier flights from Des Moines to Denver, start at $65, American Airlines flights from Des Moines to Philadelphia cost around $72, and Allegiant Air flights from Des Moines to Burbank are around $126.

What is the cheapest flight available from Des Moines?

Currently, the cheapest flight from Des Moines found by our users is for $34 to Philadelphia. Prices will vary according to several factors such as the departure date and time, but on average you can expect to pay around $267 to travel from Des Moines to Philadelphia.

Which destinations have the most frequent flights from Des Moines?

Chicago, Chicago O'Hare Intl Airport and Atlanta are currently the destinations served most frequently from Des Moines, with 43, 41 and 12 flights per day on average, respectively.

Which airlines can you fly with from Des Moines?

Airlines including American Airlines, Delta and United Airlines frequently fly from Des Moines. You can view other airlines by performing a quick search in the form above.

What is the cheapest first class flight from Des Moines?

If you are looking for a cheap first class flight, consider flights to Chicago O'Hare Intl Airport, for which the starting price of a first class seat can be as low as $743.

When did momondo last update prices for flights from Des Moines Airport?

Prices for flights from Des Moines Airport were last updated today.

How many operators does momondo search for flights from Des Moines Airport?

There are 33 operators available for flights from Des Moines Airport as of November 2026.

How old do you have to be to fly from Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.