Cheap flights from Des Moines to Denver from $86

The cheapest month to fly to Denver from Des Moines is in February. Flight prices, which tend to average around $179, are often lower during this time because this is during the off-season. If you don’t want to visit Denver in February, then you should wait until December to fly from Des Moines, when ticket prices are also cheap, with an average price of $188.

The cheapest day to depart on your flight to Denver is on a Friday when prices can be found for as low as $348. This is often the case because there is less demand to fly during this day of the week. The most expensive day to fly to Denver is Sunday, with ticket prices averaging around $498.

The cheapest time of day to fly to Denver is in the evening when flights can be purchased for as low as $227. Flights in the morning are often more expensive with an average ticket price of $463.

Fly from Des Moines to Denver Intl for the best Des Moines - Denver Intl flight prices

You are more likely to see cheaper flights to Denver from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Denver for around $248 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Denver from Des Moines for as low as $195 on momondo.

There are 4 cabin classes available to choose from on Des Moines to Denver flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Frontier, United Airlines, and Delta are the most popular carriers operating from Des Moines to Denver Intl

United Airlines, Frontier and Southwest are the top three most popular airlines that fly to Denver from Des Moines according to our data. United Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Denver. Keep in mind that there are 4 different airlines that fly to Denver on a routine basis, so you have a few additional options to choose from.

The number of flights available between Des Moines and Denver is 9 per day as of September 2026. The most frequent departure time is 9:00AM, with 48% of daily flights leaving in the afternoon.

As of September 2026, 65 flights take off from Des Moines and land in Denver each week. The most common flight departure day for this route is Wed, with 20% of weekly flights taking off on this day.