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Cheap flights from Des Moines to Key West from $255

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:50 pm - 12:36 pmDSM  Des Moines-EYW Key West
20h 46m1 stop Tampa St. Petersburg
Multiple Airlines Logo
3:57 pm - 11:01 pmEYW  Key West-DSM Des Moines
8h 04m1 stop Tampa St. Petersburg
$255Multiple Airlines
Mon, Dec 14 - Fri, Dec 18
Multiple Airlines Logo
2:50 pm - 12:36 pmDSM  Des Moines-EYW Key West
20h 46m1 stop Tampa St. Petersburg
Multiple Airlines Logo
10:59 am - 10:22 pmEYW  Key West-DSM Des Moines
12h 23m1 stop Orlando
$277Multiple Airlines
Mon, Dec 14 - Thu, Dec 17
Allegiant Air Logo
8:30 am - 1:12 pmDSM  Des Moines-EYW Key West
27h 42m2 stops Sarasota Bradenton Intl Knoxville McGhee Tyson
Allegiant Air Logo
3:57 pm - 11:01 pmEYW  Key West-DSM Des Moines
8h 04m1 stop Tampa St. Petersburg
$285Allegiant Air
Sun, Dec 13 - Fri, Dec 18
American Airlines Logo
2:02 pm - 10:36 pmDSM  Des Moines-EYW Key West
7h 34m1 stop Charlotte Douglas
American Airlines Logo
8:05 am - 1:11 pmEYW  Key West-DSM Des Moines
6h 06m1 stop Charlotte Douglas
$349American Airlines
Wed, Apr 7 - Wed, Apr 14
American Airlines Logo
10:57 am - 5:54 pmDSM  Des Moines-EYW Key West
5h 57m1 stop Charlotte Douglas
American Airlines Logo
5:58 pm - 12:26 amEYW  Key West-DSM Des Moines
7h 28m1 stop Chicago O'Hare Intl
$349American Airlines
Tue, Jan 26 - Tue, Feb 2
American Airlines Logo
7:14 am - 4:46 pmDSM  Des Moines-EYW Key West
8h 32m1 stop Chicago O'Hare Intl
American Airlines Logo
6:42 pm - 12:25 amEYW  Key West-DSM Des Moines
6h 43m1 stop Chicago O'Hare Intl
$349American Airlines
Tue, Dec 8 - Tue, Dec 15
United Airlines Logo
8:00 am - 3:26 pmDSM  Des Moines-EYW Key West
6h 26m1 stop Chicago O'Hare Intl
United Airlines Logo
4:04 pm - 9:23 pmEYW  Key West-DSM Des Moines
6h 19m1 stop Chicago O'Hare Intl
$469United Airlines
Wed, Dec 9 - Thu, Dec 17
United Airlines Logo
8:00 am - 3:26 pmDSM  Des Moines-EYW Key West
6h 26m1 stop Chicago O'Hare Intl
United Airlines Logo
4:04 pm - 9:23 pmEYW  Key West-DSM Des Moines
6h 19m1 stop Chicago O'Hare Intl
$469United Airlines
Wed, Dec 9 - Fri, Dec 18
Delta Logo
11:38 am - 5:10 pmDSM  Des Moines-EYW Key West
4h 32m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:06 pm - 10:38 pmEYW  Key West-DSM Des Moines
5h 32m1 stop Atlanta Hartsfield-Jackson
$474Delta
Sat, Dec 12 - Wed, Dec 16
Delta Logo
11:38 am - 5:10 pmDSM  Des Moines-EYW Key West
4h 32m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:06 pm - 10:38 pmEYW  Key West-DSM Des Moines
5h 32m1 stop Atlanta Hartsfield-Jackson
$474Delta
Wed, Dec 9 - Wed, Dec 16

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Allegiant Air flights from Des Moines to Key West

Our best Allegiant Air deals on Des Moines to Key West flight tickets
Allegiant Air
Dec 13
DSM8:30 amDes Moines
27h 42m
2 stops
EYW1:12 pmKey West
Dec 18
EYW3:57 pmKey West
8h 04m
1 stop
DSM11:01 pmDes Moines
$285
Allegiant Air
Dec 11
DSM2:50 pmDes Moines
25h 46m
1 stop
EYW5:36 pmKey West
Dec 18
EYW3:57 pmKey West
8h 04m
1 stop
DSM11:01 pmDes Moines
$371
Allegiant Air
Dec 13
DSM8:30 amDes Moines
27h 42m
2 stops
EYW1:12 pmKey West
Dec 14
EYW3:58 pmKey West
6h 35m
1 stop
DSM9:33 pmDes Moines
$392

United Airlines flights from Des Moines to Key West

Our best United Airlines deals on Des Moines to Key West flight tickets
United Airlines
Dec 9
DSM8:00 amDes Moines
6h 26m
1 stop
EYW3:26 pmKey West
Dec 18
EYW12:22 pmKey West
12h 37m
2 stops
DSM11:59 pmDes Moines
$474
United Airlines
Nov 12
DSM8:00 amDes Moines
6h 29m
1 stop
EYW3:29 pmKey West
Nov 15
EYW4:10 pmKey West
7h 49m
1 stop
DSM10:59 pmDes Moines
$1,306
United Airlines
Nov 12
DSM8:00 amDes Moines
6h 29m
1 stop
EYW3:29 pmKey West
Nov 15
EYW2:52 pmKey West
32h 03m
2 stops
DSM9:55 pmDes Moines
$1,369

momondo Fare Finder

 
Use the filters below to find and compare flights from Des Moines to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Mon 12/14

2:50 pm-12:36 pm

1 stop20h 46m

Key West

Fri 12/18

3:57 pm-11:01 pm

1 stop8h 04m

$255

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Mon 12/14

2:50 pm-12:36 pm

1 stop20h 46m

Key West

Thu 12/17

10:59 am-10:22 pm

1 stop12h 23m

$277

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sun 12/13

8:30 am-1:12 pm

2 stops27h 42m

Key West

Fri 12/18

3:57 pm-11:01 pm

1 stop8h 04m

$285

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Wed 4/7

2:02 pm-10:36 pm

1 stop7h 34m

Key West

Wed 4/14

8:05 am-1:11 pm

1 stop6h 06m

$349

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Tue 1/26

10:57 am-5:54 pm

1 stop5h 57m

Key West

Tue 2/2

5:58 pm-12:26 am

1 stop7h 28m

$349

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Tue 12/8

7:14 am-4:46 pm

1 stop8h 32m

Key West

Tue 12/15

6:42 pm-12:25 am

1 stop6h 43m

$349

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Wed 12/9

8:00 am-3:26 pm

1 stop6h 26m

Key West

Thu 12/17

4:04 pm-9:23 pm

1 stop6h 19m

$469

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Wed 12/9

8:00 am-3:26 pm

1 stop6h 26m

Key West

Fri 12/18

4:04 pm-9:23 pm

1 stop6h 19m

$469
Quickest round-trip

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 12/12

11:38 am-5:10 pm

1 stop4h 32m

Key West

Wed 12/16

6:06 pm-10:38 pm

1 stop5h 32m

$474

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Wed 12/9

11:38 am-5:10 pm

1 stop4h 32m

Key West

Wed 12/16

6:06 pm-10:38 pm

1 stop5h 32m

$474

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Key West from

How to get the cheapest flight ticket from Des Moines to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Key West?

Prices are currently low for flights on this route.

Typical prices usually range from $403 to $598.
The lowest price recently found on this route was $255.

What is the cheapest month to fly to Key West?

In general, July is the cheapest month to fly from Des Moines to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $378. If you are unable to visit Key West during the month of July, then departing from Des Moines during the month January is also very affordable. Most momondo users find prices during this month for around $437.

When to book flights from Des Moines to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Key West (DSM to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Key West

Best Price Found

$255

Fastest flight time

4h 32m

Direct flights

None
The best flight deal from Des Moines to Key West found on momondo in the last 72 hours is $255
The fastest flight from Des Moines to Key West takes 4h 32m
There are no direct flights from Des Moines to Key West. There are no popular flight routes from Des Moines to Key West.
Search flight deals

Frequently asked questions about flying from Des Moines to Key West

  • How far is Des Moines to Key West by plane?

    The distance between Des Moines and Key West is about 1357.4 mi. 4h 32m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Key West Airport?

    Prices for flights from Des Moines Airport to Key West Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Key West Airport?

  • How old do you have to be to fly from Des Moines Airport to Key West Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Key West?

Best airlines flying from Des Moines to Key West

Compare and see reviews for airlines that fly from Des Moines to Key West with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $289Free CancellationRating
7.3
10,471 reviews
Search United Airlines flights
American AirlinesPriceFrom $318Free CancellationRating
7.0
12,224 reviews
Search American Airlines flights
DeltaPriceFrom $338Free CancellationRating
7.8
8,700 reviews
Search Delta flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Key West?

It is quick and easy to find Des Moines to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Des Moines to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Des Moines.

I’m not ready to book a flight from Des Moines to Key West right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Key West now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Key West and let you know when they change.

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