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Cheap flights from Des Moines to Key West from $230

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
11:35 am - 8:01 pmDSM  Des Moines-EYW Key West
7h 26m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:06 pm - 10:38 pmEYW  Key West-DSM Des Moines
5h 32m1 stop Atlanta Hartsfield-Jackson
$339Delta
Sat, Dec 5 - Wed, Dec 9
Multiple Airlines Logo
12:59 pm - 11:20 amDSM  Des Moines-EYW Key West
21h 21m1 stop Orlando Sanford Intl
Multiple Airlines Logo
4:40 pm - 4:46 pmEYW  Key West-DSM Des Moines
25h 06m2 stops Tampa St. Petersburg Fort Lauderdale
$345Multiple Airlines
Sat, Dec 5 - Wed, Dec 9
American Airlines Logo
7:30 am - 5:21 pmDSM  Des Moines-EYW Key West
8h 51m1 stop Charlotte Douglas
American Airlines Logo
6:35 pm - 10:59 pmEYW  Key West-DSM Des Moines
5h 24m1 stop Miami
$349American Airlines
Sat, Dec 5 - Tue, Dec 8
American Airlines Logo
7:30 am - 5:21 pmDSM  Des Moines-EYW Key West
8h 51m1 stop Charlotte Douglas
American Airlines Logo
5:50 pm - 11:30 pmEYW  Key West-DSM Des Moines
6h 40m1 stop Charlotte Douglas
$349American Airlines
Sat, Dec 5 - Wed, Dec 9
Multiple Airlines Logo
12:59 pm - 11:20 amDSM  Des Moines-EYW Key West
21h 21m1 stop Orlando Sanford Intl
Multiple Airlines Logo
10:45 am - 4:46 pmEYW  Key West-DSM Des Moines
31h 01m2 stops Tampa Fort Lauderdale
$363Multiple Airlines
Sat, Dec 5 - Wed, Dec 9
Allegiant Air Logo
8:59 am - 9:02 amDSM  Des Moines-EYW Key West
23h 03m1 stop Tampa St. Petersburg
Allegiant Air Logo
8:54 am - 7:54 amEYW  Key West-DSM Des Moines
24h 00m1 stop Tampa St. Petersburg
$366Allegiant Air
Fri, Oct 30 - Thu, Nov 5
Delta Logo
1:00 pm - 7:43 pmDSM  Des Moines-EYW Key West
5h 43m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 pm - 10:29 pmEYW  Key West-DSM Des Moines
5h 29m1 stop Atlanta Hartsfield-Jackson
$399Delta
Sat, Feb 6 - Wed, Feb 10
Delta Logo
11:27 am - 8:01 pmDSM  Des Moines-EYW Key West
7h 34m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:11 pm - 10:33 pmEYW  Key West-DSM Des Moines
5h 22m1 stop Atlanta Hartsfield-Jackson
$408Delta
Sat, Oct 31 - Thu, Nov 5
United Airlines Logo
9:25 am - 5:13 pmDSM  Des Moines-EYW Key West
6h 48m1 stop Chicago O'Hare Intl
United Airlines Logo
5:54 pm - 11:14 pmEYW  Key West-DSM Des Moines
6h 20m1 stop Chicago O'Hare Intl
$547United Airlines
Thu, Jan 7 - Mon, Jan 11
United Airlines Logo
8:00 am - 5:13 pmDSM  Des Moines-EYW Key West
8h 13m1 stop Chicago O'Hare Intl
United Airlines Logo
5:54 pm - 11:14 pmEYW  Key West-DSM Des Moines
6h 20m1 stop Chicago O'Hare Intl
$582United Airlines
Thu, Jan 7 - Mon, Jan 11

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Allegiant Air flights from Des Moines to Key West

Our best Allegiant Air deals on Des Moines to Key West flight tickets
Allegiant Air
Oct 30
DSM8:59 amDes Moines
23h 03m
1 stop
EYW9:02 amKey West
Nov 5
EYW8:54 amKey West
24h 00m
1 stop
DSM7:54 amDes Moines
$366
Allegiant Air
Oct 30
DSM9:15 amDes Moines
52h 28m
2 stops
EYW2:43 pmKey West
Nov 5
EYW8:54 amKey West
24h 00m
1 stop
DSM7:54 amDes Moines
$404
Allegiant Air
Nov 11
DSM12:46 pmDes Moines
23h 10m
1 stop
EYW12:56 pmKey West
Nov 15
EYW8:54 pmKey West
26h 37m
1 stop
DSM10:31 pmDes Moines
$476

United Airlines flights from Des Moines to Key West

Our best United Airlines deals on Des Moines to Key West flight tickets
United Airlines
Jan 7
DSM9:25 amDes Moines
6h 48m
1 stop
EYW5:13 pmKey West
Jan 11
EYW5:54 pmKey West
6h 20m
1 stop
DSM11:14 pmDes Moines
$547
United Airlines
Jan 7
DSM8:00 amDes Moines
8h 13m
1 stop
EYW5:13 pmKey West
Jan 11
EYW5:54 pmKey West
6h 20m
1 stop
DSM11:14 pmDes Moines
$582
United Airlines
Oct 19
DSM8:00 amDes Moines
28h 29m
3 stops
EYW1:29 pmKey West
Oct 24
EYW2:15 pmKey West
10h 19m
2 stops
DSM11:34 pmDes Moines
$887

momondo Fare Finder

 
Use the filters below to find and compare flights from Des Moines to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 12/5

11:35 am-8:01 pm

1 stop7h 26m

Key West

Wed 12/9

6:06 pm-10:38 pm

1 stop5h 32m

$339

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 12/5

12:59 pm-11:20 am

1 stop21h 21m

Key West

Wed 12/9

4:40 pm-4:46 pm

2 stops25h 06m

$345

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 12/5

7:30 am-5:21 pm

1 stop8h 51m

Key West

Tue 12/8

6:35 pm-10:59 pm

1 stop5h 24m

$349

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 12/5

7:30 am-5:21 pm

1 stop8h 51m

Key West

Wed 12/9

5:50 pm-11:30 pm

1 stop6h 40m

$349

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 12/5

12:59 pm-11:20 am

1 stop21h 21m

Key West

Wed 12/9

10:45 am-4:46 pm

2 stops31h 01m

$363

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Fri 10/30

8:59 am-9:02 am

1 stop23h 03m

Key West

Thu 11/5

8:54 am-7:54 am

1 stop24h 00m

$366
Quickest round-trip

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 2/6

1:00 pm-7:43 pm

1 stop5h 43m

Key West

Wed 2/10

6:00 pm-10:29 pm

1 stop5h 29m

$399

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 10/31

11:27 am-8:01 pm

1 stop7h 34m

Key West

Thu 11/5

6:11 pm-10:33 pm

1 stop5h 22m

$408

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Thu 1/7

9:25 am-5:13 pm

1 stop6h 48m

Key West

Mon 1/11

5:54 pm-11:14 pm

1 stop6h 20m

$547

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Thu 1/7

8:00 am-5:13 pm

1 stop8h 13m

Key West

Mon 1/11

5:54 pm-11:14 pm

1 stop6h 20m

$582

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Des Moines to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Key West?

Prices are currently low for flights on this route.

Typical prices usually range from $456 to $655.
The lowest price recently found on this route was $339.

What is the cheapest month to fly to Key West?

In general, July is the cheapest month to fly from Des Moines to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $378. If you are unable to visit Key West during the month of July, then departing from Des Moines during the month March is also very affordable. Most momondo users find prices during this month for around $446.

When to book flights from Des Moines to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Key West (DSM to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Key West

Best Price Found

$230

Fastest flight time

6h 23m

Direct flights

None
The best one-way flight to Key West from Des Moines in the past 72 hours is $230. The best round-trip flight deal from Des Moines to Key West found on momondo in the last 72 hours is $339.
The fastest flight from Des Moines to Key West takes 6h 23m
There are no direct flights from Des Moines to Key West. There are no popular flight routes from Des Moines to Key West.
Search flight deals

Frequently asked questions about flying from Des Moines to Key West

  • How far is Des Moines to Key West by plane?

    The distance between Des Moines and Key West is about 1357.4 mi. 6h 23m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Key West Airport?

    Prices for flights from Des Moines Airport to Key West Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Key West Airport?

  • How old do you have to be to fly from Des Moines Airport to Key West Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Key West?

Best airlines flying from Des Moines to Key West

Compare and see reviews for airlines that fly from Des Moines to Key West with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $288Free CancellationRating
7.4
10,384 reviews
Search United Airlines flights
American AirlinesPriceFrom $305Free CancellationRating
7.0
12,175 reviews
Search American Airlines flights
DeltaPriceFrom $338Free CancellationRating
7.8
8,652 reviews
Search Delta flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Key West?

It is quick and easy to find Des Moines to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Des Moines to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Des Moines.

I’m not ready to book a flight from Des Moines to Key West right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Key West now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Key West and let you know when they change.

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