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Cheap flights from Des Moines to Key West from $165

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
9:00 am - 1:38 pmDSM  Des Moines-EYW Key West
27h 38m1 stop Orlando Sanford Intl
Allegiant Air Logo
8:54 pm - 8:21 amEYW  Key West-DSM Des Moines
12h 27m1 stop Orlando Sanford Intl
$283Allegiant Air
Sat, Oct 31 - Thu, Nov 5
Multiple Airlines Logo
9:00 am - 11:19 amDSM  Des Moines-EYW Key West
25h 19m1 stop Orlando Sanford Intl
Multiple Airlines Logo
12:01 pm - 7:54 amEYW  Key West-DSM Des Moines
20h 53m1 stop Tampa
$298Multiple Airlines
Sat, Oct 31 - Thu, Nov 5
Delta Logo
11:04 am - 7:43 pmDSM  Des Moines-EYW Key West
7h 39m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 pm - 10:29 pmEYW  Key West-DSM Des Moines
5h 29m1 stop Atlanta Hartsfield-Jackson
$319Delta
Tue, Jan 26 - Wed, Feb 10
Multiple Airlines Logo
9:00 am - 1:38 pmDSM  Des Moines-EYW Key West
27h 38m1 stop Orlando Sanford Intl
Multiple Airlines Logo
10:04 am - 3:25 pmEYW  Key West-DSM Des Moines
30h 21m2 stops Tampa Fort Lauderdale
$327Multiple Airlines
Sat, Oct 31 - Wed, Nov 4
American Airlines Logo
2:01 pm - 10:43 pmDSM  Des Moines-EYW Key West
7h 42m1 stop Charlotte Douglas
American Airlines Logo
8:03 am - 1:16 pmEYW  Key West-DSM Des Moines
6h 13m1 stop Charlotte Douglas
$339American Airlines
Fri, Feb 19 - Wed, Feb 24
American Airlines Logo
2:01 pm - 10:43 pmDSM  Des Moines-EYW Key West
7h 42m1 stop Charlotte Douglas
American Airlines Logo
8:03 am - 1:16 pmEYW  Key West-DSM Des Moines
6h 13m1 stop Charlotte Douglas
$339American Airlines
Fri, Feb 26 - Tue, Mar 2
Delta Logo
1:00 pm - 7:43 pmDSM  Des Moines-EYW Key West
5h 43m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 pm - 10:29 pmEYW  Key West-DSM Des Moines
5h 29m1 stop Atlanta Hartsfield-Jackson
$391Delta
Sat, Jan 30 - Wed, Feb 10
Delta Logo
11:04 am - 7:43 pmDSM  Des Moines-EYW Key West
7h 39m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 pm - 10:29 pmEYW  Key West-DSM Des Moines
5h 29m1 stop Atlanta Hartsfield-Jackson
$391Delta
Thu, Jan 28 - Wed, Feb 10
United Airlines Logo
8:00 am - 5:11 pmDSM  Des Moines-EYW Key West
8h 11m1 stop Chicago O'Hare Intl
United Airlines Logo
4:52 pm - 10:29 pmEYW  Key West-DSM Des Moines
6h 37m1 stop Houston George Bush Intcntl
$541United Airlines
Mon, Dec 21 - Sat, Dec 26
United Airlines Logo
5:00 am - 2:36 pmDSM  Des Moines-EYW Key West
8h 36m1 stop Chicago O'Hare Intl
United Airlines Logo
4:00 pm - 9:17 pmEYW  Key West-DSM Des Moines
6h 17m1 stop Chicago O'Hare Intl
$544United Airlines
Tue, Mar 9 - Thu, Mar 18

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American Airlines flights from Des Moines to Key West

Our best American Airlines deals on Des Moines to Key West flight tickets
American Airlines
Feb 19
DSM2:01 pmDes Moines
7h 42m
1 stop
EYW10:43 pmKey West
Feb 24
EYW8:03 amKey West
6h 13m
1 stop
DSM1:16 pmDes Moines
$339
American Airlines
Jan 7
DSM10:26 amDes Moines
6h 02m
1 stop
EYW5:28 pmKey West
Jan 11
EYW5:58 pmKey West
7h 28m
1 stop
DSM12:26 amDes Moines
$359
American Airlines
Dec 5
DSM7:14 amDes Moines
7h 57m
1 stop
EYW4:11 pmKey West
Dec 9
EYW6:35 pmKey West
5h 24m
1 stop
DSM10:59 pmDes Moines
$368

Delta flights from Des Moines to Key West

Our best Delta deals on Des Moines to Key West flight tickets
Delta
Jan 26
DSM11:04 amDes Moines
7h 39m
1 stop
EYW7:43 pmKey West
Feb 10
EYW6:00 pmKey West
5h 29m
1 stop
DSM10:29 pmDes Moines
$319
Delta
Jan 26
DSM11:04 amDes Moines
7h 39m
1 stop
EYW7:43 pmKey West
Feb 8
EYW6:00 pmKey West
5h 29m
1 stop
DSM10:29 pmDes Moines
$448
Delta
Oct 7
DSM11:27 amDes Moines
4h 48m
1 stop
EYW5:15 pmKey West
Oct 12
EYW6:10 pmKey West
5h 23m
1 stop
DSM10:33 pmDes Moines
$774

momondo Fare Finder

 
Use the filters below to find and compare flights from Des Moines to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 10/31

9:00 am-1:38 pm

1 stop27h 38m

Key West

Thu 11/5

8:54 pm-8:21 am

1 stop12h 27m

$283

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 10/31

9:00 am-11:19 am

1 stop25h 19m

Key West

Thu 11/5

12:01 pm-7:54 am

1 stop20h 53m

$298

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Tue 1/26

11:04 am-7:43 pm

1 stop7h 39m

Key West

Wed 2/10

6:00 pm-10:29 pm

1 stop5h 29m

$319

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 10/31

9:00 am-1:38 pm

1 stop27h 38m

Key West

Wed 11/4

10:04 am-3:25 pm

2 stops30h 21m

$327

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Fri 2/19

2:01 pm-10:43 pm

1 stop7h 42m

Key West

Wed 2/24

8:03 am-1:16 pm

1 stop6h 13m

$339

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Fri 2/26

2:01 pm-10:43 pm

1 stop7h 42m

Key West

Tue 3/2

8:03 am-1:16 pm

1 stop6h 13m

$339
Quickest round-trip

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 1/30

1:00 pm-7:43 pm

1 stop5h 43m

Key West

Wed 2/10

6:00 pm-10:29 pm

1 stop5h 29m

$391

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Thu 1/28

11:04 am-7:43 pm

1 stop7h 39m

Key West

Wed 2/10

6:00 pm-10:29 pm

1 stop5h 29m

$391

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Mon 12/21

8:00 am-5:11 pm

1 stop8h 11m

Key West

Sat 12/26

4:52 pm-10:29 pm

1 stop6h 37m

$541

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Tue 3/9

5:00 am-2:36 pm

1 stop8h 36m

Key West

Thu 3/18

4:00 pm-9:17 pm

1 stop6h 17m

$544

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Des Moines to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Key West?

Prices are currently low for flights on this route.

Typical prices usually range from $456 to $655.
The lowest price recently found on this route was $283.

What is the cheapest month to fly to Key West?

In general, July is the cheapest month to fly from Des Moines to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $378. If you are unable to visit Key West during the month of July, then departing from Des Moines during the month March is also very affordable. Most momondo users find prices during this month for around $446.

When to book flights from Des Moines to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Key West (DSM to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Key West

Best Price Found

$165

Fastest flight time

4h 48m

Direct flights

None
The best one-way flight to Key West from Des Moines in the past 72 hours is $165. The best round-trip flight deal from Des Moines to Key West found on momondo in the last 72 hours is $283.
The fastest flight from Des Moines to Key West takes 4h 48m
There are no direct flights from Des Moines to Key West. There are no popular flight routes from Des Moines to Key West.
Search flight deals

Frequently asked questions about flying from Des Moines to Key West

  • How far is Des Moines to Key West by plane?

    The distance between Des Moines and Key West is about 1357.4 mi. 4h 48m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Key West Airport?

    Prices for flights from Des Moines Airport to Key West Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Key West Airport?

  • How old do you have to be to fly from Des Moines Airport to Key West Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Key West?

Best airlines flying from Des Moines to Key West

Compare and see reviews for airlines that fly from Des Moines to Key West with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $288Free CancellationRating
7.4
10,270 reviews
Search United Airlines flights
American AirlinesPriceFrom $305Free CancellationRating
7.0
12,101 reviews
Search American Airlines flights
DeltaPriceFrom $308Free CancellationRating
7.8
8,615 reviews
Search Delta flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Key West?

It is quick and easy to find Des Moines to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Des Moines to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Des Moines.

I’m not ready to book a flight from Des Moines to Key West right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Key West now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Key West and let you know when they change.

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