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Cheap flights from Des Moines to Key West from $252

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:00 am - 12:19 pmDSM  Des Moines-EYW Key West
27h 19m2 stops Philadelphia Tampa
Multiple Airlines Logo
12:01 pm - 8:09 amEYW  Key West-DSM Des Moines
21h 08m1 stop Tampa
$265Multiple Airlines
Sun, Oct 25 - Thu, Oct 29
Multiple Airlines Logo
8:43 am - 9:24 amDSM  Des Moines-EYW Key West
47h 41m2 stops Philadelphia Tampa
Multiple Airlines Logo
8:54 pm - 8:21 amEYW  Key West-DSM Des Moines
12h 27m1 stop Orlando Sanford Intl
$281Multiple Airlines
Thu, Oct 29 - Thu, Nov 5
Multiple Airlines Logo
8:59 am - 9:24 amDSM  Des Moines-EYW Key West
23h 25m1 stop Tampa St. Petersburg
Multiple Airlines Logo
12:01 pm - 8:09 amEYW  Key West-DSM Des Moines
21h 08m1 stop Tampa
$288Multiple Airlines
Fri, Oct 23 - Thu, Oct 29
American Airlines Logo
9:49 am - 4:54 pmDSM  Des Moines-EYW Key West
6h 05m1 stop Dallas/Fort Worth
American Airlines Logo
6:43 pm - 11:20 pmEYW  Key West-DSM Des Moines
5h 37m1 stop Charlotte Douglas
$299American Airlines
Sat, Jan 30 - Wed, Feb 3
United Airlines Logo
8:00 am - 3:06 pmDSM  Des Moines-EYW Key West
6h 06m1 stop Chicago O'Hare Intl
United Airlines Logo
4:05 pm - 11:01 pmEYW  Key West-DSM Des Moines
7h 56m1 stop Chicago O'Hare Intl
$299United Airlines
Wed, Jan 6 - Wed, Jan 13
United Airlines Logo
6:15 am - 4:22 pmDSM  Des Moines-EYW Key West
9h 07m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
United Airlines Logo
4:05 pm - 11:01 pmEYW  Key West-DSM Des Moines
7h 56m1 stop Chicago O'Hare Intl
$304United Airlines
Sat, Jan 30 - Wed, Feb 3
American Airlines Logo
11:22 am - 6:49 pmDSM  Des Moines-EYW Key West
6h 27m1 stop Charlotte Douglas
American Airlines Logo
1:12 pm - 6:54 pmEYW  Key West-DSM Des Moines
6h 42m1 stop Chicago O'Hare Intl
$319American Airlines
Fri, Oct 30 - Wed, Nov 4
Delta Logo
5:40 am - 12:26 pmDSM  Des Moines-EYW Key West
5h 46m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:19 pm - 10:26 pmEYW  Key West-DSM Des Moines
5h 07m1 stop Atlanta Hartsfield-Jackson
$319Delta
Sun, Sep 6 - Wed, Sep 9
Delta Logo
11:28 am - 8:02 pmDSM  Des Moines-EYW Key West
7h 34m1 stop Atlanta Hartsfield-Jackson
Delta Logo
11:43 am - 6:05 pmEYW  Key West-DSM Des Moines
7h 22m1 stop Atlanta Hartsfield-Jackson
$319Delta
Mon, Nov 23 - Wed, Dec 2
American Airlines Logo
9:49 am - 4:54 pmDSM  Des Moines-EYW Key West
6h 05m1 stop Dallas/Fort Worth
American Airlines Logo
1:05 pm - 7:09 pmEYW  Key West-DSM Des Moines
7h 04m1 stop Chicago O'Hare Intl
$319American Airlines
Sat, Jan 30 - Thu, Feb 4

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American Airlines flights from Des Moines to Key West

Our best American Airlines deals on Des Moines to Key West flight tickets
American Airlines
Oct 24
DSM11:22 amDes Moines
6h 27m
1 stop
EYW6:49 pmKey West
Oct 30
EYW7:19 pmKey West
5h 39m
1 stop
DSM11:58 pmDes Moines
$339
American Airlines
Dec 5
DSM7:23 amDes Moines
7h 53m
1 stop
EYW4:16 pmKey West
Dec 9
EYW6:25 pmKey West
7h 01m
1 stop
DSM12:26 amDes Moines
$348
American Airlines
Nov 7
DSM11:09 amDes Moines
5h 47m
1 stop
EYW5:56 pmKey West
Nov 14
EYW10:18 amKey West
5h 28m
1 stop
DSM2:46 pmDes Moines
$368

Allegiant Air flights from Des Moines to Key West

Our best Allegiant Air deals on Des Moines to Key West flight tickets
Allegiant Air
Oct 23
DSM8:59 amDes Moines
23h 03m
1 stop
EYW9:02 amKey West
Oct 29
EYW8:37 amKey West
24h 32m
1 stop
DSM8:09 amDes Moines
$291
Allegiant Air
Oct 18
DSM8:43 amDes Moines
33h 51m
2 stops
EYW7:34 pmKey West
Oct 22
EYW8:36 pmKey West
12h 49m
1 stop
DSM8:25 amDes Moines
$297
Allegiant Air
Oct 19
DSM8:00 amDes Moines
5h 04m
1 stop
EYW2:04 pmKey West
Oct 22
EYW8:36 pmKey West
12h 49m
1 stop
DSM8:25 amDes Moines
$338

momondo Fare Finder

 
Use the filters below to find and compare flights from Des Moines to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sun 10/25

8:00 am-12:19 pm

2 stops27h 19m

Key West

Thu 10/29

12:01 pm-8:09 am

1 stop21h 08m

$265

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Thu 10/29

8:43 am-9:24 am

2 stops47h 41m

Key West

Thu 11/5

8:54 pm-8:21 am

1 stop12h 27m

$281

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Fri 10/23

8:59 am-9:24 am

1 stop23h 25m

Key West

Thu 10/29

12:01 pm-8:09 am

1 stop21h 08m

$288

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 1/30

9:49 am-4:54 pm

1 stop6h 05m

Key West

Wed 2/3

6:43 pm-11:20 pm

1 stop5h 37m

$299

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Wed 1/6

8:00 am-3:06 pm

1 stop6h 06m

Key West

Wed 1/13

4:05 pm-11:01 pm

1 stop7h 56m

$299

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 1/30

6:15 am-4:22 pm

2 stops9h 07m

Key West

Wed 2/3

4:05 pm-11:01 pm

1 stop7h 56m

$304

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Fri 10/30

11:22 am-6:49 pm

1 stop6h 27m

Key West

Wed 11/4

1:12 pm-6:54 pm

1 stop6h 42m

$319
Quickest round-trip

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sun 9/6

5:40 am-12:26 pm

1 stop5h 46m

Key West

Wed 9/9

6:19 pm-10:26 pm

1 stop5h 07m

$319

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Mon 11/23

11:28 am-8:02 pm

1 stop7h 34m

Key West

Wed 12/2

11:43 am-6:05 pm

1 stop7h 22m

$319

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 1/30

9:49 am-4:54 pm

1 stop6h 05m

Key West

Thu 2/4

1:05 pm-7:09 pm

1 stop7h 04m

$319

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Key West from

How to get the cheapest flight ticket from Des Moines to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Key West?

Prices are currently low for flights on this route.

Typical prices usually range from $352 to $557.
The lowest price recently found on this route was $265.

What is the cheapest month to fly to Key West?

In general, September is the cheapest month to fly from Des Moines to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $323. If you are unable to visit Key West during the month of September, then departing from Des Moines during the month July is also very affordable. Most momondo users find prices during this month for around $378.

When to book flights from Des Moines to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Key West (DSM to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Key West

Best Price Found

$252

Fastest flight time

5h 46m

Direct flights

None
The best one-way flight to Key West from Des Moines in the past 72 hours is $252. The best round-trip flight deal from Des Moines to Key West found on momondo in the last 72 hours is $265.
The fastest flight from Des Moines to Key West takes 5h 46m
There are no direct flights from Des Moines to Key West. There are no popular flight routes from Des Moines to Key West.
Search flight deals

Frequently asked questions about flying from Des Moines to Key West

  • How far is Des Moines to Key West by plane?

    The distance between Des Moines and Key West is about 1357.4 mi. 5h 46m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Key West Airport?

    Prices for flights from Des Moines Airport to Key West Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Key West Airport?

  • How old do you have to be to fly from Des Moines Airport to Key West Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Key West?

Best airlines flying from Des Moines to Key West

Compare and see reviews for airlines that fly from Des Moines to Key West with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $268Free CancellationRating
7.8
8,514 reviews
Search Delta flights
United AirlinesPriceFrom $288Free CancellationRating
7.4
10,113 reviews
Search United Airlines flights
American AirlinesPriceFrom $289Free CancellationRating
7.1
11,983 reviews
Search American Airlines flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Key West?

It is quick and easy to find Des Moines to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Des Moines to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Des Moines.

I’m not ready to book a flight from Des Moines to Key West right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Key West now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Key West and let you know when they change.

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