Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Key West from $244

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Key West

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
11:01 am - 3:09 pmDSM  Des Moines-EYW Key West
27h 08m1 stop Tampa St. Petersburg
Allegiant Air Logo
7:22 pm - 2:10 pmEYW  Key West-DSM Des Moines
19h 48m1 stop Orlando Sanford Intl
$299Allegiant Air
Fri, Nov 27 - Thu, Dec 3
Multiple Airlines Logo
12:59 pm - 11:20 amDSM  Des Moines-EYW Key West
21h 21m1 stop Orlando Sanford Intl
Multiple Airlines Logo
4:40 pm - 4:46 pmEYW  Key West-DSM Des Moines
25h 06m2 stops Tampa St. Petersburg Fort Lauderdale
$302Multiple Airlines
Sat, Dec 5 - Wed, Dec 9
Multiple Airlines Logo
11:01 am - 3:09 pmDSM  Des Moines-EYW Key West
27h 08m1 stop Tampa St. Petersburg
Multiple Airlines Logo
10:59 am - 9:50 amEYW  Key West-DSM Des Moines
23h 51m2 stops Orlando Nashville Intl
$317Multiple Airlines
Fri, Nov 27 - Thu, Dec 3
American Airlines Logo
7:30 am - 5:21 pmDSM  Des Moines-EYW Key West
8h 51m1 stop Charlotte Douglas
American Airlines Logo
5:50 pm - 11:30 pmEYW  Key West-DSM Des Moines
6h 40m1 stop Charlotte Douglas
$339American Airlines
Sat, Dec 5 - Wed, Dec 9
American Airlines Logo
2:02 pm - 10:36 pmDSM  Des Moines-EYW Key West
7h 34m1 stop Charlotte Douglas
American Airlines Logo
8:05 am - 1:11 pmEYW  Key West-DSM Des Moines
6h 06m1 stop Charlotte Douglas
$339American Airlines
Wed, Apr 7 - Wed, Apr 14
Delta Logo
11:36 am - 8:00 pmDSM  Des Moines-EYW Key West
7h 24m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:06 pm - 10:38 pmEYW  Key West-DSM Des Moines
5h 32m1 stop Atlanta Hartsfield-Jackson
$339Delta
Wed, Nov 25 - Wed, Dec 2
Delta Logo
11:38 am - 8:01 pmDSM  Des Moines-EYW Key West
7h 23m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:06 pm - 10:38 pmEYW  Key West-DSM Des Moines
5h 32m1 stop Atlanta Hartsfield-Jackson
$339Delta
Sat, Dec 5 - Wed, Dec 9
American Airlines Logo
7:30 am - 5:21 pmDSM  Des Moines-EYW Key West
8h 51m1 stop Charlotte Douglas
American Airlines Logo
5:50 pm - 11:30 pmEYW  Key West-DSM Des Moines
6h 40m1 stop Charlotte Douglas
$339American Airlines
Sat, Dec 5 - Wed, Dec 9
United Airlines Logo
6:15 am - 5:07 pmDSM  Des Moines-EYW Key West
9h 52m2 stops Chicago O'Hare Intl Newark
United Airlines Logo
4:45 pm - 10:33 pmEYW  Key West-DSM Des Moines
6h 48m1 stop Houston George Bush Intcntl
$344United Airlines
Tue, Mar 16 - Tue, Mar 23
United Airlines Logo
9:27 am - 5:11 pmDSM  Des Moines-EYW Key West
6h 44m1 stop Chicago O'Hare Intl
United Airlines Logo
4:04 pm - 11:17 pmEYW  Key West-DSM Des Moines
8h 13m1 stop Chicago O'Hare Intl
$359United Airlines
Thu, Dec 17 - Sun, Dec 20

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Delta flights from Des Moines to Key West

Our best Delta deals on Des Moines to Key West flight tickets
Delta
Dec 5
DSM11:38 amDes Moines
7h 23m
1 stop
EYW8:01 pmKey West
Dec 9
EYW6:06 pmKey West
5h 32m
1 stop
DSM10:38 pmDes Moines
$339
Delta
Nov 23
DSM11:36 amDes Moines
7h 24m
1 stop
EYW8:00 pmKey West
Dec 2
EYW11:43 amKey West
7h 25m
1 stop
DSM6:08 pmDes Moines
$349
Delta
Nov 25
DSM11:36 amDes Moines
7h 24m
1 stop
EYW8:00 pmKey West
Dec 1
EYW6:06 pmKey West
5h 32m
1 stop
DSM10:38 pmDes Moines
$419

American Airlines flights from Des Moines to Key West

Our best American Airlines deals on Des Moines to Key West flight tickets
American Airlines
Dec 21
DSM9:53 amDes Moines
5h 53m
1 stop
EYW4:46 pmKey West
Dec 28
EYW5:56 pmKey West
7h 37m
1 stop
DSM12:33 amDes Moines
$389
American Airlines
Dec 17
DSM9:53 amDes Moines
5h 53m
1 stop
EYW4:46 pmKey West
Dec 20
EYW7:18 pmKey West
5h 40m
1 stop
DSM11:58 pmDes Moines
$404
American Airlines
Dec 8
DSM8:00 amDes Moines
8h 44m
1 stop
EYW5:44 pmKey West
Dec 12
EYW1:07 pmKey West
7h 27m
1 stop
DSM7:34 pmDes Moines
$422

momondo Fare Finder

 
Use the filters below to find and compare flights from Des Moines to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Fri 11/27

11:01 am-3:09 pm

1 stop27h 08m

Key West

Thu 12/3

7:22 pm-2:10 pm

1 stop19h 48m

$299

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 12/5

12:59 pm-11:20 am

1 stop21h 21m

Key West

Wed 12/9

4:40 pm-4:46 pm

2 stops25h 06m

$302

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Fri 11/27

11:01 am-3:09 pm

1 stop27h 08m

Key West

Thu 12/3

10:59 am-9:50 am

2 stops23h 51m

$317

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 12/5

7:30 am-5:21 pm

1 stop8h 51m

Key West

Wed 12/9

5:50 pm-11:30 pm

1 stop6h 40m

$339

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Wed 4/7

2:02 pm-10:36 pm

1 stop7h 34m

Key West

Wed 4/14

8:05 am-1:11 pm

1 stop6h 06m

$339

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Wed 11/25

11:36 am-8:00 pm

1 stop7h 24m

Key West

Wed 12/2

6:06 pm-10:38 pm

1 stop5h 32m

$339
Quickest round-trip

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 12/5

11:38 am-8:01 pm

1 stop7h 23m

Key West

Wed 12/9

6:06 pm-10:38 pm

1 stop5h 32m

$339

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Sat 12/5

7:30 am-5:21 pm

1 stop8h 51m

Key West

Wed 12/9

5:50 pm-11:30 pm

1 stop6h 40m

$339

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Tue 3/16

6:15 am-5:07 pm

2 stops9h 52m

Key West

Tue 3/23

4:45 pm-10:33 pm

1 stop6h 48m

$344

Des MoinesKey West

DSM Des Moines - EYW Key West

DSMEYW

Des Moines

Thu 12/17

9:27 am-5:11 pm

1 stop6h 44m

Key West

Sun 12/20

4:04 pm-11:17 pm

1 stop8h 13m

$359

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Key West from

How to get the cheapest flight ticket from Des Moines to Key West

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Key West?

Prices are currently low for flights on this route.

Typical prices usually range from $403 to $598.
The lowest price recently found on this route was $299.

What is the cheapest month to fly to Key West?

In general, July is the cheapest month to fly from Des Moines to Key West. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $378. If you are unable to visit Key West during the month of July, then departing from Des Moines during the month March is also very affordable. Most momondo users find prices during this month for around $446.

When to book flights from Des Moines to Key West

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Key West according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Key West (DSM to EYW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Key West

Best Price Found

$244

Fastest flight time

4h 32m

Direct flights

None
The best one-way flight to Key West from Des Moines in the past 72 hours is $244. The best round-trip flight deal from Des Moines to Key West found on momondo in the last 72 hours is $299.
The fastest flight from Des Moines to Key West takes 4h 32m
There are no direct flights from Des Moines to Key West. There are no popular flight routes from Des Moines to Key West.
Search flight deals

Frequently asked questions about flying from Des Moines to Key West

  • How far is Des Moines to Key West by plane?

    The distance between Des Moines and Key West is about 1357.4 mi. 4h 32m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Key West Airport?

    Prices for flights from Des Moines Airport to Key West Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Key West Airport?

  • How old do you have to be to fly from Des Moines Airport to Key West Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Key West Airport.

  • What documentation or ID do you need to fly to Key West Airport?

    The necessary travel and health documents for your Key West Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Key West?

Best airlines flying from Des Moines to Key West

Compare and see reviews for airlines that fly from Des Moines to Key West with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $288Free CancellationRating
7.3
10,451 reviews
Search United Airlines flights
American AirlinesPriceFrom $305Free CancellationRating
7.0
12,210 reviews
Search American Airlines flights
DeltaPriceFrom $338Free CancellationRating
7.8
8,692 reviews
Search Delta flights

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Big Pine Key
Little Torch Key

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Key West?

It is quick and easy to find Des Moines to Key West flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Key West that suits you.

Can I find flights from Des Moines to Key West with flexible booking policies on momondo?

momondo does allow users to show only those flights to Key West from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Key West?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Key West from Des Moines.

I’m not ready to book a flight from Des Moines to Key West right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Key West now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Key West and let you know when they change.

An easier way to manage your Key West trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 11/29
Sun 12/6
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States