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Cheap flights from Sicily to Los Angeles from $383

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Sicily to Los Angeles departing on 4/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Sicily to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
12:05 pm - 10:05 pm
PMO
-
SNA
19h 00m
2 stops
American Airlines Logo
12:27 pm - 6:40 pm
SNA
-
PMO
21h 13m
2 stops
$524American Airlines
Thu, Apr 23 - Sun, Apr 26
American Airlines Logo
12:05 pm - 11:05 am
PMO
-
SNA
32h 00m
2 stops
American Airlines Logo
1:23 pm - 11:45 am
SNA
-
PMO
37h 22m
2 stops
$543American Airlines
Thu, Apr 23 - Mon, Apr 27
Lufthansa Logo
7:20 am - 8:48 pm
PMO
-
SNA
22h 28m
2 stops
Lufthansa Logo
1:21 pm - 5:20 pm
SNA
-
PMO
18h 59m
2 stops
$579Lufthansa
Sat, Apr 4 - Wed, Apr 8
American Airlines Logo
11:55 am - 10:05 am
PMO
-
SNA
31h 10m
2 stops
American Airlines Logo
7:20 pm - 6:40 pm
SNA
-
PMO
38h 20m
2 stops
$1,001American Airlines
Sat, Apr 4 - Wed, Apr 8
Multiple Airlines Logo
11:15 am - 8:47 pm
PMO
-
SNA
18h 32m
2 stops
Multiple Airlines Logo
1:21 pm - 3:20 pm
SNA
-
PMO
16h 59m
2 stops
$2,152Multiple Airlines
Sun, Apr 12 - Sat, Apr 18
Multiple Airlines Logo
11:50 am - 9:30 pm
PMO
-
SNA
18h 40m
2 stops
Multiple Airlines Logo
12:52 pm - 3:20 pm
SNA
-
PMO
17h 28m
2 stops
$5,133Multiple Airlines
Tue, Jun 16 - Sat, Jun 27
Multiple Airlines Logo
11:50 am - 9:30 pm
PMO
-
SNA
18h 40m
2 stops
Multiple Airlines Logo
2:40 pm - 5:20 pm
SNA
-
PMO
17h 40m
2 stops
$8,143Multiple Airlines
Thu, Jul 30 - Fri, Aug 7

American Airlines flights from Sicily to Santa Ana

Our best American Airlines deals on Sicily to Santa Ana flight tickets
American Airlines
Apr 23
PMO12:05 pmPalermo Punta Raisi
19h 00m
2 stops
SNA10:05 pmSanta Ana J. Wayne/Orange Cnty
Apr 26
SNA12:27 pmSanta Ana J. Wayne/Orange Cnty
21h 13m
2 stops
PMO6:40 pmPalermo Punta Raisi
$524
American Airlines
Apr 23
PMO12:05 pmPalermo Punta Raisi
32h 00m
2 stops
SNA11:05 amSanta Ana J. Wayne/Orange Cnty
Apr 27
SNA1:23 pmSanta Ana J. Wayne/Orange Cnty
37h 22m
2 stops
PMO11:45 amPalermo Punta Raisi
$543
American Airlines
Apr 4
PMO11:55 amPalermo Punta Raisi
31h 10m
2 stops
SNA10:05 amSanta Ana J. Wayne/Orange Cnty
Apr 8
SNA7:20 pmSanta Ana J. Wayne/Orange Cnty
38h 20m
2 stops
PMO6:40 pmPalermo Punta Raisi
$1,001

momondo Fare Finder

 
Customize your flight search to find flights from Sicily to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Sicily to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PalermoSanta Ana

PMO - SNA

PMOSNA

Palermo Punta Raisi

Thu 4/23

12:05 pm-10:05 pm

2 stops19h 00m

Santa Ana J. Wayne/Orange Cnty

Sun 4/26

12:27 pm-6:40 pm

2 stops21h 13m

$524

PalermoSanta Ana

PMO - SNA

PMOSNA

Palermo Punta Raisi

Thu 4/23

12:05 pm-11:05 am

2 stops32h 00m

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

1:23 pm-11:45 am

2 stops37h 22m

$543

PalermoSanta Ana

PMO - SNA

PMOSNA

Palermo Punta Raisi

Sat 4/4

7:20 am-8:48 pm

2 stops22h 28m

Santa Ana J. Wayne/Orange Cnty

Wed 4/8

1:21 pm-5:20 pm

2 stops18h 59m

$579

PalermoSanta Ana

PMO - SNA

PMOSNA

Palermo Punta Raisi

Sat 4/4

11:55 am-10:05 am

2 stops31h 10m

Santa Ana J. Wayne/Orange Cnty

Wed 4/8

7:20 pm-6:40 pm

2 stops38h 20m

$1,001
Quickest round-trip

PalermoSanta Ana

PMO - SNA

PMOSNA

Palermo Punta Raisi

Sun 4/12

11:15 am-8:47 pm

2 stops18h 32m

Santa Ana J. Wayne/Orange Cnty

Sat 4/18

1:21 pm-3:20 pm

2 stops16h 59m

$2,152

PalermoSanta Ana

PMO - SNA

PMOSNA

Palermo Punta Raisi

Tue 6/16

11:50 am-9:30 pm

2 stops18h 40m

Santa Ana J. Wayne/Orange Cnty

Sat 6/27

12:52 pm-3:20 pm

2 stops17h 28m

$5,133

PalermoSanta Ana

PMO - SNA

PMOSNA

Palermo Punta Raisi

Thu 7/30

11:50 am-9:30 pm

2 stops18h 40m

Santa Ana J. Wayne/Orange Cnty

Fri 8/7

2:40 pm-5:20 pm

2 stops17h 40m

$8,143
Cheapest one-way

PalermoSanta Ana

PMO - SNA

PMOSNA

Palermo Punta Raisi

Thu 4/23

6:10 am-5:56 pm

3 stops44h 46m

$383

PalermoSanta Ana

PMO - SNA

PMOSNA

Palermo Punta Raisi

Fri 4/24

11:20 pm-11:28 am

3 stops45h 08m

$400

PalermoSanta Ana

PMO - SNA

PMOSNA

Palermo Punta Raisi

Thu 4/23

6:10 am-8:50 am

3 stops35h 40m

$402

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from Sicily to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

How long does it take to fly to Santa Ana?

Flight times from Sicily to Santa Ana vary, but if you’re flying out of Palermo and flying into Los Angeles (one of the most popular routes), then the duration is 15h 45m on average. Another popular route from Sicily to Santa Ana is flying from Catania to Los Angeles, which will take roughly 16h 15m. Keep in mind that layovers or delays could extend your travel time.

Cheap Sicily to Santa Ana flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Sicily to Santa Ana

Fastest flight time

18h 40m

Direct flights

None
The fastest flight from Sicily to Santa Ana takes 18h 40m
There are no direct flights from Sicily to Santa Ana. There are no popular flight routes from Sicily to Santa Ana.
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  • When did momondo last update prices for flights from Sicily to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Sicily to Santa Ana J. Wayne/Orange Cnty Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Sicily to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Sicily to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The necessary travel and health documents for your Santa Ana J. Wayne/Orange Cnty Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Sicily to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Sicily to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Sicily to Santa Ana with flexible booking policies on momondo?

Yes. All flights to Santa Ana from Sicily on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Sicily to Santa Ana?

momondo provides multiple filters to help you find the best flight to Santa Ana from Sicily. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Sicily to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Sicily to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

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