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Cheap flights from Santo Domingo to Houston from $282

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Houston departing on 9/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Santo Domingo to Houston

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:02 pm - 1:33 pmSDQ  Santo Domingo Las Americas-IAH Houston George Bush Intcntl
21h 31m1 stop Miami
Multiple Airlines Logo
2:18 pm - 4:29 pmIAH  Houston George Bush Intcntl-SDQ Santo Domingo Las Americas
25h 11m1 stop Miami
$389Multiple Airlines
Thu, Sep 17 - Tue, Sep 22
Multiple Airlines Logo
3:35 pm - 10:30 pmSDQ  Santo Domingo Las Americas-IAH Houston George Bush Intcntl
31h 55m2 stops Miami Atlanta Hartsfield-Jackson
Multiple Airlines Logo
2:18 pm - 4:29 pmIAH  Houston George Bush Intcntl-SDQ Santo Domingo Las Americas
25h 11m1 stop Miami
$404Multiple Airlines
Tue, Sep 15 - Tue, Sep 22
Multiple Airlines Logo
10:19 am - 10:03 amSDQ  Santo Domingo Las Americas-IAH Houston George Bush Intcntl
24h 44m1 stop Miami
Multiple Airlines Logo
7:42 pm - 9:45 pmIAH  Houston George Bush Intcntl-SDQ Santo Domingo Las Americas
25h 03m1 stop Miami
$405Multiple Airlines
Fri, Sep 25 - Fri, Oct 16
Multiple Airlines Logo
10:19 am - 11:23 amSDQ  Santo Domingo Las Americas-IAH Houston George Bush Intcntl
26h 04m2 stops Miami Atlanta Hartsfield-Jackson
Multiple Airlines Logo
2:18 pm - 4:29 pmIAH  Houston George Bush Intcntl-SDQ Santo Domingo Las Americas
25h 11m1 stop Miami
$414Multiple Airlines
Wed, Sep 16 - Tue, Sep 22
JetBlue Logo
3:59 pm - 9:55 pmSDQ  Santo Domingo Las Americas-IAH Houston George Bush Intcntl
6h 56m1 stop Fort Lauderdale
JetBlue Logo
6:15 am - 2:49 pmIAH  Houston George Bush Intcntl-SDQ Santo Domingo Las Americas
7h 34m1 stop Fort Lauderdale
$507JetBlue
Thu, Sep 24 - Mon, Sep 28
JetBlue Logo
3:59 pm - 9:55 pmSDQ  Santo Domingo Las Americas-IAH Houston George Bush Intcntl
6h 56m1 stop Fort Lauderdale
JetBlue Logo
6:15 am - 2:49 pmIAH  Houston George Bush Intcntl-SDQ Santo Domingo Las Americas
7h 34m1 stop Fort Lauderdale
$577JetBlue
Mon, Sep 21 - Sat, Sep 26
JetBlue Logo
5:01 am - 11:47 amSDQ  Santo Domingo Las Americas-IAH Houston George Bush Intcntl
7h 46m1 stop Fort Lauderdale
JetBlue Logo
1:08 pm - 1:16 amIAH  Houston George Bush Intcntl-SDQ Santo Domingo Las Americas
11h 08m1 stop Boston Logan Intl
$593JetBlue
Sun, Aug 30 - Sun, Sep 6
American Airlines Logo
6:00 am - 6:45 pmSDQ  Santo Domingo Las Americas-IAH Houston George Bush Intcntl
14h 45m2 stops Miami Dallas/Fort Worth
American Airlines Logo
11:10 am - 10:26 pmIAH  Houston George Bush Intcntl-SDQ Santo Domingo Las Americas
9h 16m2 stops Charlotte Douglas Miami
$698American Airlines
Tue, Dec 22 - Tue, Jan 12
American Airlines Logo
7:34 pm - 11:01 amSDQ  Santo Domingo Las Americas-HOU Houston Hobby
16h 27m2 stops Miami Dallas/Fort Worth
American Airlines Logo
6:04 am - 6:34 pmHOU  Houston Hobby-SDQ Santo Domingo Las Americas
11h 30m2 stops Dallas/Fort Worth Miami
$704American Airlines
Wed, Sep 16 - Wed, Sep 23
American Airlines Logo
3:16 pm - 11:50 pmSDQ  Santo Domingo Las Americas-IAH Houston George Bush Intcntl
10h 34m2 stops Miami Dallas/Fort Worth
American Airlines Logo
8:00 am - 10:26 pmIAH  Houston George Bush Intcntl-SDQ Santo Domingo Las Americas
12h 26m2 stops Charlotte Douglas Miami
$704American Airlines
Fri, Dec 25 - Wed, Jan 6

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JetBlue flights from Santo Domingo to Houston

Our best JetBlue deals on Santo Domingo to Houston flight tickets
JetBlue
Sep 24
SDQ3:59 pmSanto Domingo Las Americas
6h 56m
1 stop
IAH9:55 pmHouston George Bush Intcntl
Sep 28
IAH6:15 amHouston George Bush Intcntl
7h 34m
1 stop
SDQ2:49 pmSanto Domingo Las Americas
$507
JetBlue
Sep 21
SDQ3:59 pmSanto Domingo Las Americas
6h 56m
1 stop
IAH9:55 pmHouston George Bush Intcntl
Sep 26
IAH6:15 amHouston George Bush Intcntl
7h 34m
1 stop
SDQ2:49 pmSanto Domingo Las Americas
$577
JetBlue
Aug 30
SDQ5:01 amSanto Domingo Las Americas
7h 46m
1 stop
IAH11:47 amHouston George Bush Intcntl
Sep 6
IAH1:08 pmHouston George Bush Intcntl
11h 08m
1 stop
SDQ1:16 amSanto Domingo Las Americas
$593

Delta flights from Santo Domingo to Houston

Our best Delta deals on Santo Domingo to Houston flight tickets
Delta
Sep 1
SDQ2:53 pmSanto Domingo Las Americas
8h 12m
1 stop
HOU10:05 pmHouston Hobby
Sep 30
HOU6:00 amHouston Hobby
6h 27m
1 stop
SDQ1:27 pmSanto Domingo Las Americas
$675
Delta
Oct 6
SDQ2:57 pmSanto Domingo Las Americas
9h 06m
1 stop
HOU11:03 pmHouston Hobby
Nov 6
HOU6:09 amHouston Hobby
6h 23m
1 stop
SDQ2:32 pmSanto Domingo Las Americas
$698
Delta
Sep 1
SDQ2:53 pmSanto Domingo Las Americas
8h 12m
1 stop
HOU10:05 pmHouston Hobby
Sep 29
HOU6:00 amHouston Hobby
6h 27m
1 stop
SDQ1:27 pmSanto Domingo Las Americas
$728

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 6, 2026.
Use the filters below to find and compare flights from Santo Domingo to Houston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoHouston

SDQ Santo Domingo Las Americas - IAH Houston George Bush Intcntl

SDQIAH

Santo Domingo Las Americas

Thu 9/17

5:02 pm-1:33 pm

1 stop21h 31m

Houston George Bush Intcntl

Tue 9/22

2:18 pm-4:29 pm

1 stop25h 11m

$389

Santo DomingoHouston

SDQ Santo Domingo Las Americas - IAH Houston George Bush Intcntl

SDQIAH

Santo Domingo Las Americas

Tue 9/15

3:35 pm-10:30 pm

2 stops31h 55m

Houston George Bush Intcntl

Tue 9/22

2:18 pm-4:29 pm

1 stop25h 11m

$404

Santo DomingoHouston

SDQ Santo Domingo Las Americas - IAH Houston George Bush Intcntl

SDQIAH

Santo Domingo Las Americas

Fri 9/25

10:19 am-10:03 am

1 stop24h 44m

Houston George Bush Intcntl

Fri 10/16

7:42 pm-9:45 pm

1 stop25h 03m

$405

Santo DomingoHouston

SDQ Santo Domingo Las Americas - IAH Houston George Bush Intcntl

SDQIAH

Santo Domingo Las Americas

Wed 9/16

10:19 am-11:23 am

2 stops26h 04m

Houston George Bush Intcntl

Tue 9/22

2:18 pm-4:29 pm

1 stop25h 11m

$414
Quickest round-trip

Santo DomingoHouston

SDQ Santo Domingo Las Americas - IAH Houston George Bush Intcntl

SDQIAH

Santo Domingo Las Americas

Thu 9/24

3:59 pm-9:55 pm

1 stop6h 56m

Houston George Bush Intcntl

Mon 9/28

6:15 am-2:49 pm

1 stop7h 34m

$507

Santo DomingoHouston

SDQ Santo Domingo Las Americas - IAH Houston George Bush Intcntl

SDQIAH

Santo Domingo Las Americas

Mon 9/21

3:59 pm-9:55 pm

1 stop6h 56m

Houston George Bush Intcntl

Sat 9/26

6:15 am-2:49 pm

1 stop7h 34m

$577

Santo DomingoHouston

SDQ Santo Domingo Las Americas - IAH Houston George Bush Intcntl

SDQIAH

Santo Domingo Las Americas

Sun 8/30

5:01 am-11:47 am

1 stop7h 46m

Houston George Bush Intcntl

Sun 9/6

1:08 pm-1:16 am

1 stop11h 08m

$593

Santo DomingoHouston

SDQ Santo Domingo Las Americas - IAH Houston George Bush Intcntl

SDQIAH

Santo Domingo Las Americas

Tue 12/22

6:00 am-6:45 pm

2 stops14h 45m

Houston George Bush Intcntl

Tue 1/12

11:10 am-10:26 pm

2 stops9h 16m

$698

Santo DomingoHouston

SDQ Santo Domingo Las Americas - HOU Houston Hobby

SDQHOU

Santo Domingo Las Americas

Wed 9/16

7:34 pm-11:01 am

2 stops16h 27m

Houston Hobby

Wed 9/23

6:04 am-6:34 pm

2 stops11h 30m

$704

Santo DomingoHouston

SDQ Santo Domingo Las Americas - IAH Houston George Bush Intcntl

SDQIAH

Santo Domingo Las Americas

Fri 12/25

3:16 pm-11:50 pm

2 stops10h 34m

Houston George Bush Intcntl

Wed 1/6

8:00 am-10:26 pm

2 stops12h 26m

$704

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Houston from

How to get the cheapest flight ticket from Santo Domingo to Houston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santo Domingo and Houston?

Prices are currently low for flights on this route.

Typical prices usually range from $425 to $518.
The lowest price recently found on this route was $389.

What is the cheapest month to fly to Houston?

The month of October is, on average, the cheapest month to fly to Houston from Santo Domingo, with most prices found around $355. The month of August is another great option to travel to Houston, with average flight prices from Santo Domingo averaging around $498.

Cheap Santo Domingo to Houston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Houston

Fastest flight time

8h 12m

Direct flights

Mon, Thu and Sat

Airports in Houston

2 airports
The fastest flight from Santo Domingo to Houston takes 8h 12m
Direct flights go from Santo Domingo to Houston on Monday, Thursday and Saturday. There are no airlines offering direct flights.
There are 2 airports in Houston. From Santo Domingo there are direct flights to Houston George Bush Intcntl (IAH).
Search flight deals

Frequently asked questions about flying from Santo Domingo to Houston

  • How far is Santo Domingo Las Americas to Houston by plane?

    There are 1776.2 mi between Santo Domingo Las Americas and Houston. Flights usually cover this in 8h 12m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Houston?

    Prices for flights from Santo Domingo Las Americas Airport to Houston are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to Houston?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Houston?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santo Domingo Las Americas Airport to Houston.

  • What documentation or ID do you need to fly to Houston?

    The required travel and health documents for your Houston trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Houston. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Santo Domingo to Houston

Compare and see reviews for airlines that fly from Santo Domingo to Houston with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $386Free CancellationRating
7.1
3,024 reviews
Search JetBlue flights
American AirlinesPriceFrom $598Free CancellationRating
7.1
11,866 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Houston?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santo Domingo to Houston for you.

Can I find flights from Santo Domingo to Houston with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Houston from Santo Domingo with this policy.

How can momondo help me find flights from Santo Domingo to Houston?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Santo Domingo to Houston.

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