Cheap flights from Pennsylvania to Knoxville from $33

The month of August is, on average, the cheapest month to fly to Knoxville from Pennsylvania, with most prices found around $276. If you aren’t able to travel during the month of August, then book flights to Knoxville from Pennsylvania during July instead. Flights to Knoxville in July, while not as cheap as those in August, still average around $277.

The cheapest day to depart from Pennsylvania to Knoxville is on a Thursday. Travelers who choose to depart for Knoxville on a Thursday will often find tickets for as low as $208. When flying out on a Wednesday, the most expensive travel day of the week, you can expect to see flight prices from Pennsylvania to Knoxville for around $472.

In the afternoon is the cheapest time of day to fly from Pennsylvania to Knoxville when you can find flight prices for as low as $145. Flying to Knoxville in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $503.

Fly from Philadelphia to Knoxville McGhee Tyson for the best Pennsylvania - Knoxville McGhee Tyson flight prices

You are more likely to see cheaper flights to Knoxville from Pennsylvania when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $399 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Pennsylvania for as low as $277 on momondo.

There are 3 cabin classes available to choose from on Pennsylvania to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Southwest, Delta, and United Airlines are the most popular carriers operating from Pennsylvania to Knoxville McGhee Tyson

American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to Knoxville from Pennsylvania according to our data. American Airlines is the first choice among our users, with 63% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 5 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

As of October 2026, 7 flights take off from Pennsylvania and land in Knoxville each day. The most common flight departure time for this route is 9:00AM, with 63% of daily flights taking off in the afternoon.

As of October 2026, 53 flights take off from Pennsylvania and land in Knoxville each week. The most common flight departure day for this route is Mon, with 15% of weekly flights taking off on this day.