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Cheap flights from Pennsylvania to Florence from $248

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pennsylvania to Florence departing on 9/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Pennsylvania to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:29 pm - 10:58 pmEWR  Newark-FLO Florence
5h 29m1 stop Charlotte Douglas
American Airlines Logo
1:43 pm - 8:47 pmFLO  Florence-EWR Newark
7h 04m1 stop Charlotte Douglas
$363American Airlines
Wed, Sep 9 - Wed, Sep 16
American Airlines Logo
9:30 am - 3:16 pmEWR  Newark-FLO Florence
5h 46m1 stop Charlotte Douglas
American Airlines Logo
6:24 am - 12:41 pmFLO  Florence-EWR Newark
6h 17m1 stop Charlotte Douglas
$363American Airlines
Tue, Nov 3 - Sat, Nov 7
American Airlines Logo
7:30 am - 2:09 pmEWR  Newark-FLO Florence
6h 39m1 stop Charlotte Douglas
American Airlines Logo
5:09 am - 9:50 amFLO  Florence-EWR Newark
4h 41m1 stop Charlotte Douglas
$363American Airlines
Sat, Oct 10 - Sat, Oct 17
American Airlines Logo
7:37 am - 1:18 pmEWR  Newark-FLO Florence
5h 41m1 stop Charlotte Douglas
American Airlines Logo
1:43 pm - 6:35 pmFLO  Florence-EWR Newark
4h 52m1 stop Charlotte Douglas
$363American Airlines
Sat, Sep 26 - Sat, Oct 3
American Airlines Logo
6:30 am - 1:18 pmJFK  New York John F Kennedy Intl-FLO Florence
6h 48m1 stop Charlotte Douglas
American Airlines Logo
6:24 am - 11:29 amFLO  Florence-JFK New York John F Kennedy Intl
5h 05m1 stop Charlotte Douglas
$363American Airlines
Wed, Sep 9 - Wed, Sep 16
American Airlines Logo
7:58 am - 2:09 pmJFK  New York John F Kennedy Intl-FLO Florence
6h 11m1 stop Charlotte Douglas
American Airlines Logo
2:34 pm - 8:04 pmFLO  Florence-JFK New York John F Kennedy Intl
5h 30m1 stop Charlotte Douglas
$363American Airlines
Sat, Oct 10 - Sat, Oct 17
American Airlines Logo
7:29 am - 2:09 pmLGA  New York LaGuardia-FLO Florence
6h 40m1 stop Charlotte Douglas
American Airlines Logo
2:34 pm - 6:27 pmFLO  Florence-LGA New York LaGuardia
3h 53m1 stop Charlotte Douglas
$363American Airlines
Sat, Oct 10 - Sat, Oct 17
American Airlines Logo
4:59 pm - 10:58 pmLGA  New York LaGuardia-FLO Florence
5h 59m1 stop Charlotte Douglas
American Airlines Logo
1:43 pm - 7:52 pmFLO  Florence-LGA New York LaGuardia
6h 09m1 stop Charlotte Douglas
$363American Airlines
Wed, Sep 9 - Wed, Sep 16
American Airlines Logo
5:29 pm - 10:58 pmEWR  Newark-FLO Florence
5h 29m1 stop Charlotte Douglas
American Airlines Logo
5:09 am - 9:59 amFLO  Florence-EWR Newark
4h 50m1 stop Charlotte Douglas
$420American Airlines
Fri, Sep 11 - Sun, Sep 27
American Airlines Logo
7:29 pm - 11:57 pmEWR  Newark-FLO Florence
4h 28m1 stop Charlotte Douglas
American Airlines Logo
1:43 pm - 6:35 pmFLO  Florence-EWR Newark
4h 52m1 stop Charlotte Douglas
$420American Airlines
Sun, Sep 20 - Sat, Sep 26

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American Airlines flights from Pennsylvania to Florence, South Carolina

Our best American Airlines deals on Pennsylvania to Florence, South Carolina flight tickets
American Airlines
Sep 9
LGA4:59 pmNew York LaGuardia
5h 59m
1 stop
FLO10:58 pmFlorence
Sep 16
FLO1:43 pmFlorence
6h 09m
1 stop
LGA7:52 pmNew York LaGuardia
$363
American Airlines
Sep 11
LGA7:59 amNew York LaGuardia
5h 19m
1 stop
FLO1:18 pmFlorence
Sep 27
FLO5:09 amFlorence
5h 56m
1 stop
LGA11:05 amNew York LaGuardia
$420
American Airlines
Sep 5
LGA9:59 amNew York LaGuardia
4h 13m
1 stop
FLO2:12 pmFlorence
Sep 10
FLO6:24 amFlorence
4h 41m
1 stop
LGA11:05 amNew York LaGuardia
$443

momondo Fare Finder

 
Customize your flight search to find flights from Pennsylvania to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from Pennsylvania to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

NewarkFlorence

EWR Newark - FLO Florence

EWRFLO

Newark

Wed 9/9

5:29 pm-10:58 pm

1 stop5h 29m

Florence

Wed 9/16

1:43 pm-8:47 pm

1 stop7h 04m

$363

NewarkFlorence

EWR Newark - FLO Florence

EWRFLO

Newark

Tue 11/3

9:30 am-3:16 pm

1 stop5h 46m

Florence

Sat 11/7

6:24 am-12:41 pm

1 stop6h 17m

$363

NewarkFlorence

EWR Newark - FLO Florence

EWRFLO

Newark

Sat 10/10

7:30 am-2:09 pm

1 stop6h 39m

Florence

Sat 10/17

5:09 am-9:50 am

1 stop4h 41m

$363

NewarkFlorence

EWR Newark - FLO Florence

EWRFLO

Newark

Sat 9/26

7:37 am-1:18 pm

1 stop5h 41m

Florence

Sat 10/3

1:43 pm-6:35 pm

1 stop4h 52m

$363

New YorkFlorence

JFK New York John F Kennedy Intl - FLO Florence

JFKFLO

New York John F Kennedy Intl

Wed 9/9

6:30 am-1:18 pm

1 stop6h 48m

Florence

Wed 9/16

6:24 am-11:29 am

1 stop5h 05m

$363

New YorkFlorence

JFK New York John F Kennedy Intl - FLO Florence

JFKFLO

New York John F Kennedy Intl

Sat 10/10

7:58 am-2:09 pm

1 stop6h 11m

Florence

Sat 10/17

2:34 pm-8:04 pm

1 stop5h 30m

$363

New YorkFlorence

LGA New York LaGuardia - FLO Florence

LGAFLO

New York LaGuardia

Sat 10/10

7:29 am-2:09 pm

1 stop6h 40m

Florence

Sat 10/17

2:34 pm-6:27 pm

1 stop3h 53m

$363

New YorkFlorence

LGA New York LaGuardia - FLO Florence

LGAFLO

New York LaGuardia

Wed 9/9

4:59 pm-10:58 pm

1 stop5h 59m

Florence

Wed 9/16

1:43 pm-7:52 pm

1 stop6h 09m

$363

NewarkFlorence

EWR Newark - FLO Florence

EWRFLO

Newark

Fri 9/11

5:29 pm-10:58 pm

1 stop5h 29m

Florence

Sun 9/27

5:09 am-9:59 am

1 stop4h 50m

$420
Quickest round-trip

NewarkFlorence

EWR Newark - FLO Florence

EWRFLO

Newark

Sun 9/20

7:29 pm-11:57 pm

1 stop4h 28m

Florence

Sat 9/26

1:43 pm-6:35 pm

1 stop4h 52m

$420

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Pennsylvania to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Pennsylvania to Florence?

American Airlines is the most popular carrier operating from Pennsylvania to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Frontier and Allegiant Air are the top three most popular airlines that fly to Florence, South Carolina from Pennsylvania according to our data. American Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

Cheap Pennsylvania to Florence, South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pennsylvania to Florence, South Carolina

Fastest flight time

3h 45m

Direct flights

None
The fastest flight from Pennsylvania to Florence, South Carolina takes 3h 45m
There are no direct flights from Pennsylvania to Florence, South Carolina. There are no popular flight routes from Pennsylvania to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Pennsylvania to Florence, South Carolina

  • When did momondo last update prices for flights from Pennsylvania to Florence Airport?

    Prices for flights from Pennsylvania to Florence Airport were last updated today.

  • How many operators does momondo search for flights from Pennsylvania to Florence Airport?

  • How old do you have to be to fly from Pennsylvania to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Pennsylvania to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Pennsylvania to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Pennsylvania.

Can I find flights from Pennsylvania to Florence with flexible booking policies on momondo?

Flights from Pennsylvania to Florence with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Pennsylvania to Florence?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Florence from Pennsylvania.

I’m not ready to book a flight from Pennsylvania to Florence right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Pennsylvania to Florence now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Florence and let you know when they change.

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