Cheap flights from Panama to Houston from $221

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Houston departing on 9/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama to Houston

Recent round-trip flight deals from Panama to Houston

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:10 pm - 8:24 am
PTY
-
IAH
17h 14m
2 stops
Multiple Airlines Logo
8:37 pm - 8:06 am
IAH
-
PTY
11h 29m
1 stop
$549Multiple Airlines
Thu, Jul 16 - Sun, Jul 19
Multiple Airlines Logo
3:10 pm - 8:02 am
PTY
-
IAH
16h 52m
2 stops
Multiple Airlines Logo
8:37 pm - 4:10 pm
IAH
-
PTY
19h 33m
1 stop
$560Multiple Airlines
Thu, Jul 2 - Fri, Jul 17
Multiple Airlines Logo
3:10 pm - 8:24 am
PTY
-
IAH
17h 14m
2 stops
Multiple Airlines Logo
8:37 pm - 8:30 am
IAH
-
PTY
11h 53m
1 stop
$562Multiple Airlines
Sat, Jul 11 - Sat, Jul 18
Multiple Airlines Logo
3:10 pm - 8:24 am
PTY
-
IAH
17h 14m
2 stops
Multiple Airlines Logo
8:37 pm - 8:06 am
IAH
-
PTY
11h 29m
1 stop
$565Multiple Airlines
Sat, Aug 1 - Mon, Aug 31
Multiple Airlines Logo
10:25 am - 7:25 pm
PTY
-
IAH
33h 00m
2 stops
Multiple Airlines Logo
8:37 pm - 8:06 am
IAH
-
PTY
11h 29m
1 stop
$569Multiple Airlines
Wed, Jul 8 - Wed, Jul 29
Delta Logo
2:21 pm - 10:35 pm
PTY
-
HOU
8h 14m
1 stop
Delta Logo
6:00 am - 12:56 pm
HOU
-
PTY
6h 56m
1 stop
$885Delta
Tue, Sep 22 - Tue, Oct 6
Delta Logo
2:24 pm - 12:12 pm
PTY
-
HOU
21h 48m
1 stop
Delta Logo
6:03 am - 1:09 pm
HOU
-
PTY
7h 06m
1 stop
$886Delta
Mon, Jun 22 - Mon, Jun 29
American Airlines Logo
1:16 pm - 1:25 pm
PTY
-
HOU
24h 09m
2 stops
American Airlines Logo
8:22 pm - 2:00 pm
HOU
-
PTY
17h 38m
2 stops
$914American Airlines
Tue, Sep 22 - Tue, Oct 6
American Airlines Logo
1:16 pm - 1:25 pm
PTY
-
HOU
24h 09m
2 stops
American Airlines Logo
8:22 pm - 2:00 pm
HOU
-
PTY
17h 38m
2 stops
$915American Airlines
Tue, Sep 22 - Tue, Oct 6
American Airlines Logo
1:14 pm - 9:48 am
PTY
-
HOU
20h 34m
2 stops
American Airlines Logo
4:14 pm - 12:14 pm
HOU
-
PTY
20h 00m
2 stops
$916American Airlines
Wed, Jul 22 - Thu, Jul 30

JetBlue flights from Panama to Houston

Our best JetBlue deals on Panama to Houston flight tickets
JetBlue
Jul 22
PTY2:24 pmPanama City Tocumen Intl
19h 21m
1 stop
HOU9:45 amHouston Hobby
Jul 30
HOU6:00 amHouston Hobby
7h 05m
1 stop
PTY1:05 pmPanama City Tocumen Intl
$1,020
JetBlue
Jul 10
PTY2:24 pmPanama City Tocumen Intl
19h 10m
1 stop
HOU9:34 amHouston Hobby
Jul 17
HOU6:00 amHouston Hobby
7h 05m
1 stop
PTY1:05 pmPanama City Tocumen Intl
$1,073
JetBlue
Jun 20
PTY2:27 pmPanama City Tocumen Intl
18h 47m
1 stop
HOU9:14 amHouston Hobby
Jun 25
HOU6:03 amHouston Hobby
7h 06m
1 stop
PTY1:09 pmPanama City Tocumen Intl
$1,207

American Airlines flights from Panama to Houston

Our best American Airlines deals on Panama to Houston flight tickets
American Airlines
Sep 22
PTY1:16 pmPanama City Tocumen Intl
24h 09m
2 stops
HOU1:25 pmHouston Hobby
Oct 6
HOU8:22 pmHouston Hobby
17h 38m
2 stops
PTY2:00 pmPanama City Tocumen Intl
$914
American Airlines
Sep 22
PTY1:16 pmPanama City Tocumen Intl
24h 09m
2 stops
HOU1:25 pmHouston Hobby
Oct 6
HOU8:22 pmHouston Hobby
17h 38m
2 stops
PTY2:00 pmPanama City Tocumen Intl
$915
American Airlines
Jul 22
PTY1:14 pmPanama City Tocumen Intl
20h 34m
2 stops
HOU9:48 amHouston Hobby
Jul 30
HOU4:14 pmHouston Hobby
20h 00m
2 stops
PTY12:14 pmPanama City Tocumen Intl
$916

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 30, 2026.
Use the filters below to find and compare flights from Panama to Houston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Thu 7/16

3:10 pm-8:24 am

2 stops17h 14m

Houston George Bush Intcntl

Sun 7/19

8:37 pm-8:06 am

1 stop11h 29m

$549

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Thu 7/2

3:10 pm-8:02 am

2 stops16h 52m

Houston George Bush Intcntl

Fri 7/17

8:37 pm-4:10 pm

1 stop19h 33m

$560

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Sat 7/11

3:10 pm-8:24 am

2 stops17h 14m

Houston George Bush Intcntl

Sat 7/18

8:37 pm-8:30 am

1 stop11h 53m

$562

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Sat 8/1

3:10 pm-8:24 am

2 stops17h 14m

Houston George Bush Intcntl

Mon 8/31

8:37 pm-8:06 am

1 stop11h 29m

$565

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Wed 7/8

10:25 am-7:25 pm

2 stops33h 00m

Houston George Bush Intcntl

Wed 7/29

8:37 pm-8:06 am

1 stop11h 29m

$569
Quickest round-trip

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Tue 9/22

2:21 pm-10:35 pm

1 stop8h 14m

Houston Hobby

Tue 10/6

6:00 am-12:56 pm

1 stop6h 56m

$885

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Mon 6/22

2:24 pm-12:12 pm

1 stop21h 48m

Houston Hobby

Mon 6/29

6:03 am-1:09 pm

1 stop7h 06m

$886

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Tue 9/22

1:16 pm-1:25 pm

2 stops24h 09m

Houston Hobby

Tue 10/6

8:22 pm-2:00 pm

2 stops17h 38m

$914

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Tue 9/22

1:16 pm-1:25 pm

2 stops24h 09m

Houston Hobby

Tue 10/6

8:22 pm-2:00 pm

2 stops17h 38m

$915

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Wed 7/22

1:14 pm-9:48 am

2 stops20h 34m

Houston Hobby

Thu 7/30

4:14 pm-12:14 pm

2 stops20h 00m

$916

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Houston from

How to get the cheapest flight ticket from Panama to Houston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Houston?

The month of June is, on average, the cheapest month to fly to Houston from Panama, with most prices found around $282. The month of July is another great option to travel to Houston, with average flight prices from Panama averaging around $335.

What is the cheapest time of day to depart on your flight to Houston?

Our data shows that the cheapest Panama to Houston flights are usually those with departure times in the evening. Our users have found flights to Houston in the evening for as low as $632. Try not to purchase tickets in the morning because they tend to be around $728. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama to Houston flight route?

Fly from Panama City Tocumen Intl to Houston George Bush Intcntl for the best Panama - Houston flight prices

What cabin class options are available on Panama to Houston flights?

There are 4 cabin classes available to choose from on Panama to Houston flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Panama to Houston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Houston

Fastest flight time

4h 24m

Direct flights

Every day

Airports in Houston

2 airports
The fastest flight from Panama to Houston takes 4h 24m
Direct flights go from Panama to Houston every day.
There are 2 airports in Houston. From Panama there are direct flights to Houston George Bush Intcntl (IAH).

Frequently asked questions about flying from Panama to Houston

  • When did momondo last update prices for flights from Panama to Houston?

    Prices for flights from Panama to Houston are updated daily.

  • How many operators does momondo search for flights from Panama to Houston?

  • How old do you have to be to fly from Panama to Houston?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to Houston.

  • What documentation or ID do you need to fly to Houston?

    The required travel and health documents for your Houston trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Houston. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Panama to Houston

Compare and see reviews for airlines that fly from Panama to Houston with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $533Free CancellationRating
7.4
9,769 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $812Free CancellationRating
7.5
1,574 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Houston?

It is quick and easy to find Panama to Houston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Houston that suits you.

Can I find flights from Panama to Houston with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama to Houston flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama to Houston?

Once all potential Panama to Houston flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama to Houston right now. Can momondo alert me if prices change?

Price alerts on flights to Houston from Panama are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Mon 6/29
Mon 7/6

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