Cheap flights from Panama to Houston from $228

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Houston departing on 9/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama to Houston

Recent round-trip flight deals from Panama to Houston

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10:05 pm - 8:26 pmPTY-IAH
22h 21m2 stops
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5:37 am - 9:10 pmIAH-PTY
15h 33m2 stops
Mon, Sep 1 - Mon, Sep 8
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8:10 pm - 12:10 pmPTY-IAH
16h 00m1 stop
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2:27 pm - 4:30 pmIAH-PTY
26h 03m2 stops
Thu, Sep 4 - Tue, Sep 16
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3:40 pm - 12:10 pmPTY-IAH
20h 30m1 stop
 Logo
5:37 am - 9:10 pmIAH-PTY
15h 33m2 stops
Wed, Sep 3 - Tue, Sep 9
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9:33 pm - 9:54 amPTY-IAH
12h 21m1 stop
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10:49 am - 7:29 pmIAH-PTY
8h 40m1 stop
Fri, Sep 5 - Mon, Sep 8
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12:48 pm - 9:07 pmPTY-IAH
8h 19m1 stop
 Logo
6:43 pm - 8:11 amIAH-PTY
13h 28m1 stop
Fri, Oct 3 - Mon, Oct 6
Avianca Logo
3:20 am - 4:10 pmPTY-IAH
12h 50m2 stops
Avianca Logo
5:40 pm - 10:25 amIAH-PTY
16h 45m1 stop
$501Avianca
Find Deal
Thu, Sep 11 - Sun, Sep 21
Delta Logo
2:10 pm - 10:37 pmPTY-HOU
8h 27m1 stop
Delta Logo
6:00 am - 12:56 pmHOU-PTY
6h 56m1 stop
$787Delta
Find Deal
Tue, Sep 30 - Tue, Oct 7
American Airlines Logo
1:45 pm - 8:34 amPTY-HOU
18h 49m2 stops
American Airlines Logo
6:39 pm - 2:03 pmHOU-PTY
19h 24m2 stops
$801American Airlines
Find Deal
Tue, Sep 30 - Tue, Oct 7
Delta Logo
3:17 pm - 4:27 pmPTY-HOU
26h 10m1 stop
Delta Logo
6:00 am - 1:52 pmHOU-PTY
6h 52m1 stop
$814Delta
Find Deal
Wed, Nov 19 - Fri, Nov 28
American Airlines Logo
3:15 pm - 1:54 pmPTY-HOU
22h 39m2 stops
American Airlines Logo
4:25 pm - 1:36 pmHOU-PTY
20h 11m2 stops
$818American Airlines
Find Deal
Fri, Oct 31 - Mon, Nov 10

Delta flights from Panama to Houston

Our best Delta deals on Panama to Houston flight tickets
Delta
Sep 30
PTY2:10 pmPanama City Tocumen Intl
8h 27m
1 stop
HOU10:37 pmHouston Hobby
Oct 7
HOU6:00 amHouston Hobby
6h 56m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Delta
Nov 19
PTY3:17 pmPanama City Tocumen Intl
19h 06m
1 stop
HOU9:23 amHouston Hobby
Nov 27
HOU1:00 pmHouston Hobby
23h 52m
1 stop
PTY1:52 pmPanama City Tocumen Intl
Delta
Nov 23
PTY8:05 amPanama City Tocumen Intl
9h 22m
1 stop
HOU4:27 pmHouston Hobby
Nov 30
HOU6:00 amHouston Hobby
6h 52m
1 stop
PTY1:52 pmPanama City Tocumen Intl

American Airlines flights from Panama to Houston

Our best American Airlines deals on Panama to Houston flight tickets
American Airlines
Sep 30
PTY1:45 pmPanama City Tocumen Intl
18h 49m
2 stops
HOU8:34 amHouston Hobby
Oct 7
HOU6:39 pmHouston Hobby
19h 24m
2 stops
PTY2:03 pmPanama City Tocumen Intl
American Airlines
Oct 31
PTY3:15 pmPanama City Tocumen Intl
22h 39m
2 stops
HOU1:54 pmHouston Hobby
Nov 10
HOU4:25 pmHouston Hobby
20h 11m
2 stops
PTY1:36 pmPanama City Tocumen Intl
American Airlines
Oct 29
PTY3:15 pmPanama City Tocumen Intl
22h 41m
2 stops
HOU1:56 pmHouston Hobby
Nov 10
HOU6:37 pmHouston Hobby
17h 59m
2 stops
PTY1:36 pmPanama City Tocumen Intl

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Panama to Houston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Mon 9/1

10:05 pm-8:26 pm

2 stops22h 21m

Houston George Bush Intcntl

Mon 9/8

5:37 am-9:10 pm

2 stops15h 33m

$423

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Thu 9/4

8:10 pm-12:10 pm

1 stop16h 00m

Houston George Bush Intcntl

Tue 9/16

2:27 pm-4:30 pm

2 stops26h 03m

$424

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Wed 9/3

3:40 pm-12:10 pm

1 stop20h 30m

Houston George Bush Intcntl

Tue 9/9

5:37 am-9:10 pm

2 stops15h 33m

$425

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Fri 9/5

9:33 pm-9:54 am

1 stop12h 21m

Houston George Bush Intcntl

Mon 9/8

10:49 am-7:29 pm

1 stop8h 40m

$426

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Fri 10/3

12:48 pm-9:07 pm

1 stop8h 19m

Houston George Bush Intcntl

Mon 10/6

6:43 pm-8:11 am

1 stop13h 28m

$427

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Thu 9/11

3:20 am-4:10 pm

2 stops12h 50m

Houston George Bush Intcntl

Sun 9/21

5:40 pm-10:25 am

1 stop16h 45m

$501

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Tue 9/30

2:10 pm-10:37 pm

1 stop8h 27m

Houston Hobby

Tue 10/7

6:00 am-12:56 pm

1 stop6h 56m

$787

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Tue 9/30

1:45 pm-8:34 am

2 stops18h 49m

Houston Hobby

Tue 10/7

6:39 pm-2:03 pm

2 stops19h 24m

$801

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Wed 11/19

3:17 pm-4:27 pm

1 stop26h 10m

Houston Hobby

Fri 11/28

6:00 am-1:52 pm

1 stop6h 52m

$814

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Fri 10/31

3:15 pm-1:54 pm

2 stops22h 39m

Houston Hobby

Mon 11/10

4:25 pm-1:36 pm

2 stops20h 11m

$818

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Houston from

How to get the cheapest flight ticket from Panama to Houston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Houston?

The month of June is, on average, the cheapest month to fly to Houston from Panama, with most prices found around $808. The month of July is another great option to travel to Houston, with average flight prices from Panama averaging around $808.

What is the cheapest day to depart on your flight to Houston?

On average, the least expensive day to fly to Houston from Panama is on a Saturday. momondo users have found tickets for Saturday departures for as low as $706. However, this price may fluctuate depending on the airline, the season, and holidays. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Houston on Thursday is $1,160.

What is the cheapest time of day to depart on your flight to Houston?

Our data shows that the cheapest Panama to Houston flights are usually those with departure times at noon. Our users have found flights to Houston at noon for as low as $622. Try not to purchase tickets in the morning because they tend to be around $687. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama to Houston flight route?

Fly from Panama City Tocumen Intl to Houston George Bush Intcntl for the best Panama - Houston flight prices

How far in advance should I book a flight to Houston?

You are more likely to see cheaper flights to Houston from Panama when booking weeks ahead of your departure date. In general, you can expect to find flights to Houston for around $909 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Houston from Panama for as low as $671 on momondo.

What cabin class options are available on Panama to Houston flights?

There are 3 cabin classes available to choose from on Panama to Houston flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Panama to Houston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Houston

Best Price Found

$228

Fastest flight time

4h 20m

Direct flights

Every day

Airports in Houston

2 airports
The best one-way flight to Houston from Panama in the past 72 hours is $228. The best round-trip flight deal from Panama to Houston found on momondo in the last 72 hours is $423.
The fastest flight from Panama to Houston takes 4h 20m
Direct flights go from Panama to Houston every day.
There are 2 airports near Houston: Houston George Bush Intcntl (IAH), Houston Hobby (HOU)
  • When did momondo last update prices for flights from Panama to Houston?

    Prices for flights from Panama to Houston are updated daily.

  • How many operators does momondo search for flights from Panama to Houston?

  • How old do you have to be to fly from Panama to Houston?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to Houston.

  • What documentation or ID do you need to fly to Houston?

    The required travel and health documents for your Houston trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Houston. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Panama to Houston

Compare and see reviews for airlines that fly from Panama to Houston with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $781Free CancellationRating
7.4
8,925 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Houston?

It is quick and easy to find Panama to Houston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Houston that suits you.

Can I find flights from Panama to Houston with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama to Houston flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama to Houston?

Once all potential Panama to Houston flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama to Houston right now. Can momondo alert me if prices change?

Price alerts on flights to Houston from Panama are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Sat 8/23
Sat 8/30

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