Cheap flights from Panama to Houston from $250

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Houston departing on 1/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama to Houston

Recent round-trip flight deals from Panama to Houston

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:25 am - 10:56 pm
PTY
-
IAH
13h 31m1 stop
Multiple Airlines Logo
8:47 pm - 8:06 am
IAH
-
PTY
10h 19m1 stop
$354Multiple Airlines
Sat, Jan 24 - Sun, Feb 8
Multiple Airlines Logo
3:39 pm - 11:59 pm
PTY
-
IAH
9h 20m1 stop
Multiple Airlines Logo
5:24 pm - 8:06 am
IAH
-
PTY
13h 42m1 stop
$373Multiple Airlines
Fri, Feb 20 - Wed, Feb 25
Multiple Airlines Logo
3:39 pm - 10:56 pm
PTY
-
IAH
8h 17m1 stop
Multiple Airlines Logo
4:20 pm - 8:06 am
IAH
-
PTY
14h 46m1 stop
$395Multiple Airlines
Fri, Jan 30 - Fri, Feb 6
Multiple Airlines Logo
3:39 pm - 11:59 pm
PTY
-
IAH
9h 20m1 stop
Multiple Airlines Logo
6:00 am - 7:20 pm
IAH
-
PTY
12h 20m2 stops
$400Multiple Airlines
Fri, Feb 20 - Wed, Feb 25
Delta Logo
3:20 pm - 10:33 pm
PTY
-
HOU
8h 13m1 stop
Delta Logo
5:45 am - 1:55 pm
HOU
-
PTY
7h 10m1 stop
$776Delta
Tue, Jan 20 - Tue, Jan 27
Delta Logo
3:20 pm - 10:28 pm
PTY
-
HOU
8h 08m1 stop
Delta Logo
6:00 am - 12:55 pm
HOU
-
PTY
6h 55m1 stop
$787Delta
Thu, Mar 5 - Mon, Apr 20
American Airlines Logo
4:05 pm - 11:47 am
PTY
-
HOU
20h 42m2 stops
American Airlines Logo
8:27 pm - 12:15 pm
HOU
-
PTY
15h 48m2 stops
$815American Airlines
Thu, Mar 5 - Tue, Apr 21
American Airlines Logo
4:05 pm - 9:44 am
PTY
-
HOU
18h 39m2 stops
American Airlines Logo
6:31 pm - 12:15 pm
HOU
-
PTY
17h 44m2 stops
$818American Airlines
Thu, Mar 5 - Mon, Apr 20
American Airlines Logo
1:55 pm - 1:32 pm
PTY
-
HOU
23h 37m2 stops
American Airlines Logo
4:27 pm - 12:25 pm
HOU
-
PTY
19h 58m2 stops
$822American Airlines
Mon, May 4 - Tue, Jun 9
Delta Logo
3:20 pm - 10:33 pm
PTY
-
HOU
8h 13m1 stop
Delta Logo
5:45 am - 1:55 pm
HOU
-
PTY
7h 10m1 stop
$841Delta
Sat, Jan 31 - Sat, Feb 7

Delta flights from Panama to Houston

Our best Delta deals on Panama to Houston flight tickets
Delta
Jan 20
PTY3:20 pmPanama City Tocumen Intl
8h 13m
1 stop
HOU10:33 pmHouston Hobby
Jan 27
HOU5:45 amHouston Hobby
7h 10m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Delta
Mar 5
PTY3:20 pmPanama City Tocumen Intl
8h 08m
1 stop
HOU10:28 pmHouston Hobby
Apr 20
HOU6:00 amHouston Hobby
6h 55m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Delta
Jan 31
PTY3:20 pmPanama City Tocumen Intl
8h 13m
1 stop
HOU10:33 pmHouston Hobby
Feb 7
HOU5:45 amHouston Hobby
7h 10m
1 stop
PTY1:55 pmPanama City Tocumen Intl

American Airlines flights from Panama to Houston

Our best American Airlines deals on Panama to Houston flight tickets
American Airlines
May 5
PTY1:55 pmPanama City Tocumen Intl
23h 37m
2 stops
HOU1:32 pmHouston Hobby
Jun 2
HOU6:37 pmHouston Hobby
17h 48m
2 stops
PTY12:25 pmPanama City Tocumen Intl
American Airlines
Jan 29
PTY4:50 pmPanama City Tocumen Intl
18h 15m
2 stops
HOU10:05 amHouston Hobby
Feb 5
HOU6:36 pmHouston Hobby
17h 51m
2 stops
PTY1:27 pmPanama City Tocumen Intl
American Airlines
Mar 5
PTY4:05 pmPanama City Tocumen Intl
20h 42m
2 stops
HOU11:47 amHouston Hobby
Apr 21
HOU8:27 pmHouston Hobby
15h 48m
2 stops
PTY12:15 pmPanama City Tocumen Intl

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Panama to Houston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Sat 1/24

10:25 am-10:56 pm

1 stop13h 31m

Houston George Bush Intcntl

Sun 2/8

8:47 pm-8:06 am

1 stop10h 19m

$354

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Fri 2/20

3:39 pm-11:59 pm

1 stop9h 20m

Houston George Bush Intcntl

Wed 2/25

5:24 pm-8:06 am

1 stop13h 42m

$373

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Fri 1/30

3:39 pm-10:56 pm

1 stop8h 17m

Houston George Bush Intcntl

Fri 2/6

4:20 pm-8:06 am

1 stop14h 46m

$395

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Fri 2/20

3:39 pm-11:59 pm

1 stop9h 20m

Houston George Bush Intcntl

Wed 2/25

6:00 am-7:20 pm

2 stops12h 20m

$400

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Tue 1/20

3:20 pm-10:33 pm

1 stop8h 13m

Houston Hobby

Tue 1/27

5:45 am-1:55 pm

1 stop7h 10m

$776

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Thu 3/5

3:20 pm-10:28 pm

1 stop8h 08m

Houston Hobby

Mon 4/20

6:00 am-12:55 pm

1 stop6h 55m

$787

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Thu 3/5

4:05 pm-11:47 am

2 stops20h 42m

Houston Hobby

Tue 4/21

8:27 pm-12:15 pm

2 stops15h 48m

$815

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Thu 3/5

4:05 pm-9:44 am

2 stops18h 39m

Houston Hobby

Mon 4/20

6:31 pm-12:15 pm

2 stops17h 44m

$818

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Mon 5/4

1:55 pm-1:32 pm

2 stops23h 37m

Houston Hobby

Tue 6/9

4:27 pm-12:25 pm

2 stops19h 58m

$822

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Sat 1/31

3:20 pm-10:33 pm

1 stop8h 13m

Houston Hobby

Sat 2/7

5:45 am-1:55 pm

1 stop7h 10m

$841

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Houston from

How to get the cheapest flight ticket from Panama to Houston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Houston?

The month of June is, on average, the cheapest month to fly to Houston from Panama, with most prices found around $808. The month of July is another great option to travel to Houston, with average flight prices from Panama averaging around $808.

What is the cheapest day to depart on your flight to Houston?

On average, the least expensive day to fly to Houston from Panama is on a Saturday. momondo users have found tickets for Saturday departures for as low as $706. However, this price may fluctuate depending on the airline, the season, and holidays. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Houston on Thursday is $1,160.

What is the cheapest time of day to depart on your flight to Houston?

Our data shows that the cheapest Panama to Houston flights are usually those with departure times at noon. Our users have found flights to Houston at noon for as low as $622. Try not to purchase tickets in the morning because they tend to be around $679. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama to Houston flight route?

Fly from Panama City Tocumen Intl to Houston George Bush Intcntl for the best Panama - Houston flight prices

How far in advance should I book a flight to Houston?

You are more likely to see cheaper flights to Houston from Panama when booking weeks ahead of your departure date. In general, you can expect to find flights to Houston for around $894 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Houston from Panama for as low as $647 on momondo.

What cabin class options are available on Panama to Houston flights?

There are 4 cabin classes available to choose from on Panama to Houston flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Panama to Houston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Houston

Fastest flight time

4h 19m

Direct flights

Every day

Airports in Houston

2 airports
The fastest flight from Panama to Houston takes 4h 19m
Direct flights go from Panama to Houston every day.
There are 2 airports in Houston. From Panama there are direct flights to Houston George Bush Intcntl (IAH).
  • When did momondo last update prices for flights from Panama to Houston?

    Prices for flights from Panama to Houston are updated daily.

  • How many operators does momondo search for flights from Panama to Houston?

  • How old do you have to be to fly from Panama to Houston?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to Houston.

  • What documentation or ID do you need to fly to Houston?

    The required travel and health documents for your Houston trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Houston. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Panama to Houston

Compare and see reviews for airlines that fly from Panama to Houston with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $781Free CancellationRating
7.4
9,091 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Houston?

It is quick and easy to find Panama to Houston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Houston that suits you.

Can I find flights from Panama to Houston with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama to Houston flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama to Houston?

Once all potential Panama to Houston flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama to Houston right now. Can momondo alert me if prices change?

Price alerts on flights to Houston from Panama are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Sat 1/17
Sat 1/24

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