Cheap flights from Panama to Houston from $347

The month of February is, on average, the cheapest month to fly to Houston from Panama, with most prices found around $870. The month of April is another great option to travel to Houston, with average flight prices from Panama averaging around $922.

Our data shows that the cheapest Panama to Houston flights are usually those with departure times in the afternoon. Our users have found flights to Houston in the afternoon for as low as $747. Try not to purchase tickets in the morning because they tend to be around $767. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Panama City Tocumen Intl to Houston George Bush Intcntl for the best Panama - Houston flight prices

There are 3 cabin classes available to choose from on Panama to Houston flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Historically, on average around 5% of flights between Panama and Houston have experienced a delay on any given week. The average delay length over the past 12 months has been 132 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

According to our data, United Airlines have had the least number of delays on this route over the last 12 months; with about 5% of their flights experiencing any sort of delay.

As of September 2026, 4 flights take off from Panama and land in Houston each day. The most common flight departure time for this route is 10:00AM, with 50% of daily flights taking off at noon.

As of September 2026, there are 28 flights per week flying from Panama to Houston. The most common day of the week flights depart is Mon, with 14% of flights taking off on this day.