Cheap flights from Panama to Houston from $245

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Houston departing on 5/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama to Houston

Recent round-trip flight deals from Panama to Houston

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:34 pm - 8:18 am
PTY
-
IAH
13h 44m
1 stop
Multiple Airlines Logo
9:17 pm - 9:15 am
IAH
-
PTY
11h 58m
2 stops
$443Multiple Airlines
Sun, May 10 - Sun, May 24
Multiple Airlines Logo
6:34 pm - 8:18 am
PTY
-
IAH
13h 44m
1 stop
Multiple Airlines Logo
4:20 pm - 2:15 pm
IAH
-
PTY
21h 55m
2 stops
$452Multiple Airlines
Wed, May 13 - Wed, May 27
Multiple Airlines Logo
9:33 pm - 4:16 pm
PTY
-
IAH
18h 43m
1 stop
Multiple Airlines Logo
9:17 pm - 2:15 pm
IAH
-
PTY
16h 58m
2 stops
$456Multiple Airlines
Fri, May 8 - Mon, May 18
Multiple Airlines Logo
3:10 pm - 4:16 pm
PTY
-
IAH
25h 06m
2 stops
Multiple Airlines Logo
7:05 am - 9:15 am
IAH
-
PTY
26h 10m
2 stops
$460Multiple Airlines
Mon, May 11 - Mon, May 18
Multiple Airlines Logo
6:15 pm - 8:18 am
PTY
-
IAH
14h 03m
1 stop
Multiple Airlines Logo
9:17 pm - 8:30 am
IAH
-
PTY
11h 13m
1 stop
$469Multiple Airlines
Wed, May 6 - Mon, May 11
Delta Logo
2:15 pm - 11:54 pm
PTY
-
IAH
9h 39m
1 stop
Delta Logo
5:40 am - 1:09 pm
IAH
-
PTY
7h 29m
1 stop
$477Delta
Fri, Jun 5 - Tue, Jun 9
Delta Logo
2:15 pm - 10:26 pm
PTY
-
HOU
8h 11m
1 stop
Delta Logo
6:00 am - 1:13 pm
HOU
-
PTY
7h 13m
1 stop
$906Delta
Wed, May 13 - Wed, Aug 12
American Airlines Logo
1:14 pm - 8:57 am
PTY
-
HOU
19h 43m
2 stops
American Airlines Logo
4:15 pm - 12:14 pm
HOU
-
PTY
19h 59m
2 stops
$920American Airlines
Tue, May 26 - Tue, Jun 2
American Airlines Logo
1:49 pm - 12:12 pm
PTY
-
HOU
22h 23m
2 stops
American Airlines Logo
3:58 pm - 12:24 pm
HOU
-
PTY
20h 26m
2 stops
$939American Airlines
Wed, May 13 - Wed, Aug 12
KLM Logo
2:15 pm - 9:32 am
PTY
-
HOU
19h 17m
1 stop
KLM Logo
1:06 pm - 12:50 pm
HOU
-
PTY
23h 44m
1 stop
$948KLM
Thu, May 28 - Thu, Jun 4

Delta flights from Panama to Houston

Our best Delta deals on Panama to Houston flight tickets
Delta
Jun 5
PTY2:15 pmPanama City Tocumen Intl
9h 39m
1 stop
IAH11:54 pmHouston George Bush Intcntl
Jun 9
IAH5:40 amHouston George Bush Intcntl
7h 29m
1 stop
PTY1:09 pmPanama City Tocumen Intl
$477
Delta
May 13
PTY2:15 pmPanama City Tocumen Intl
8h 11m
1 stop
HOU10:26 pmHouston Hobby
Aug 12
HOU6:00 amHouston Hobby
7h 13m
1 stop
PTY1:13 pmPanama City Tocumen Intl
$906
Delta
May 30
PTY2:15 pmPanama City Tocumen Intl
8h 11m
1 stop
HOU10:26 pmHouston Hobby
Sep 30
HOU6:00 amHouston Hobby
6h 56m
1 stop
PTY12:56 pmPanama City Tocumen Intl
$933

American Airlines flights from Panama to Houston

Our best American Airlines deals on Panama to Houston flight tickets
American Airlines
May 26
PTY1:14 pmPanama City Tocumen Intl
19h 43m
2 stops
HOU8:57 amHouston Hobby
Jun 2
HOU4:15 pmHouston Hobby
19h 59m
2 stops
PTY12:14 pmPanama City Tocumen Intl
$920
American Airlines
May 13
PTY1:49 pmPanama City Tocumen Intl
22h 23m
2 stops
HOU12:12 pmHouston Hobby
Aug 12
HOU3:58 pmHouston Hobby
20h 26m
2 stops
PTY12:24 pmPanama City Tocumen Intl
$939
American Airlines
May 13
PTY1:49 pmPanama City Tocumen Intl
22h 23m
2 stops
HOU12:12 pmHouston Hobby
Aug 12
HOU3:58 pmHouston Hobby
20h 26m
2 stops
PTY12:24 pmPanama City Tocumen Intl
$941

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 16, 2026.
Use the filters below to find and compare flights from Panama to Houston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Sun 5/10

6:34 pm-8:18 am

1 stop13h 44m

Houston George Bush Intcntl

Sun 5/24

9:17 pm-9:15 am

2 stops11h 58m

$443

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Wed 5/13

6:34 pm-8:18 am

1 stop13h 44m

Houston George Bush Intcntl

Wed 5/27

4:20 pm-2:15 pm

2 stops21h 55m

$452

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Fri 5/8

9:33 pm-4:16 pm

1 stop18h 43m

Houston George Bush Intcntl

Mon 5/18

9:17 pm-2:15 pm

2 stops16h 58m

$456

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Mon 5/11

3:10 pm-4:16 pm

2 stops25h 06m

Houston George Bush Intcntl

Mon 5/18

7:05 am-9:15 am

2 stops26h 10m

$460

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Wed 5/6

6:15 pm-8:18 am

1 stop14h 03m

Houston George Bush Intcntl

Mon 5/11

9:17 pm-8:30 am

1 stop11h 13m

$469

Panama CityHouston

PTY - IAH

PTYIAH

Panama City Tocumen Intl

Fri 6/5

2:15 pm-11:54 pm

1 stop9h 39m

Houston George Bush Intcntl

Tue 6/9

5:40 am-1:09 pm

1 stop7h 29m

$477
Quickest round-trip

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Wed 5/13

2:15 pm-10:26 pm

1 stop8h 11m

Houston Hobby

Wed 8/12

6:00 am-1:13 pm

1 stop7h 13m

$906

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Tue 5/26

1:14 pm-8:57 am

2 stops19h 43m

Houston Hobby

Tue 6/2

4:15 pm-12:14 pm

2 stops19h 59m

$920

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Wed 5/13

1:49 pm-12:12 pm

2 stops22h 23m

Houston Hobby

Wed 8/12

3:58 pm-12:24 pm

2 stops20h 26m

$939

Panama CityHouston

PTY - HOU

PTYHOU

Panama City Tocumen Intl

Thu 5/28

2:15 pm-9:32 am

1 stop19h 17m

Houston Hobby

Thu 6/4

1:06 pm-12:50 pm

1 stop23h 44m

$948

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Houston from

How to get the cheapest flight ticket from Panama to Houston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Houston?

The month of November is, on average, the cheapest month to fly to Houston from Panama, with most prices found around $835. The month of February is another great option to travel to Houston, with average flight prices from Panama averaging around $859.

What is the cheapest time of day to depart on your flight to Houston?

Our data shows that the cheapest Panama to Houston flights are usually those with departure times in the evening. Our users have found flights to Houston in the evening for as low as $632. Try not to purchase tickets in the morning because they tend to be around $706. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama to Houston flight route?

Fly from Panama City Tocumen Intl to Houston George Bush Intcntl for the best Panama - Houston flight prices

What cabin class options are available on Panama to Houston flights?

There are 4 cabin classes available to choose from on Panama to Houston flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Panama to Houston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Houston

Fastest flight time

4h 17m

Direct flights

Every day

Airports in Houston

2 airports
The fastest flight from Panama to Houston takes 4h 17m
Direct flights go from Panama to Houston every day.
There are 2 airports in Houston. From Panama there are direct flights to Houston George Bush Intcntl (IAH).

Frequently asked questions about flying from Panama to Houston

  • When did momondo last update prices for flights from Panama to Houston?

    Prices for flights from Panama to Houston are updated daily.

  • How many operators does momondo search for flights from Panama to Houston?

  • How old do you have to be to fly from Panama to Houston?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to Houston.

  • What documentation or ID do you need to fly to Houston?

    The required travel and health documents for your Houston trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Houston. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Panama to Houston

Compare and see reviews for airlines that fly from Panama to Houston with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $781Free CancellationRating
7.4
9,594 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $812Free CancellationRating
7.5
1,575 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Houston?

It is quick and easy to find Panama to Houston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Houston that suits you.

Can I find flights from Panama to Houston with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama to Houston flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama to Houston?

Once all potential Panama to Houston flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama to Houston right now. Can momondo alert me if prices change?

Price alerts on flights to Houston from Panama are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Sat 5/16
Sat 5/23

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