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Cheap flights from Panama City to Detroit from $270

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Detroit departing on 10/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Multiple Airlines Logo
2:55 pm - 2:09 pmPTY-DTW
23h 14m2 stops
Multiple Airlines Logo
8:00 am - 12:40 amDTW-PTY
16h 40m2 stops
$490Multiple Airlines
Find Deal
mié., dic. 10 - lun., ene. 19
Multiple Airlines Logo
2:55 am - 6:26 pmPTY-DTW
15h 31m2 stops
Multiple Airlines Logo
6:50 am - 12:40 amDTW-PTY
17h 50m2 stops
$587Multiple Airlines
Find Deal
mar., dic. 9 - lun., ene. 19
Multiple Airlines Logo
2:55 am - 5:18 pmPTY-DTW
38h 23m3 stops
Multiple Airlines Logo
8:00 am - 4:55 pmDTW-PTY
32h 55m2 stops
$616Multiple Airlines
Find Deal
mar., dic. 9 - lun., ene. 19
United Airlines Logo
4:41 pm - 1:33 pmPTY-DTW
20h 52m2 stops
United Airlines Logo
8:15 am - 4:07 pmDTW-PTY
8h 52m1 stop
$621United Airlines
Find Deal
lun., mar. 2 - jue., mar. 19
Multiple Airlines Logo
9:33 pm - 2:09 pmPTY-DTW
16h 36m1 stop
Multiple Airlines Logo
7:00 am - 2:00 pmDTW-PTY
31h 00m2 stops
$645Multiple Airlines
Find Deal
mié., dic. 10 - lun., ene. 19
United Airlines Logo
4:41 pm - 3:59 pmPTY-DTW
23h 18m1 stop
United Airlines Logo
8:15 am - 5:07 pmDTW-PTY
8h 52m1 stop
$680United Airlines
Find Deal
mié., dic. 10 - lun., ene. 19
American Airlines Logo
4:56 pm - 12:18 pmPTY-DTW
19h 22m2 stops
American Airlines Logo
6:14 am - 3:35 pmDTW-PTY
9h 21m2 stops
$757American Airlines
Find Deal
jue., ene. 1 - vie., ene. 30
American Airlines Logo
4:56 pm - 12:18 pmPTY-DTW
19h 22m2 stops
American Airlines Logo
5:59 am - 3:35 pmDTW-PTY
9h 36m1 stop
$758American Airlines
Find Deal
jue., ene. 1 - vie., ene. 30
United Airlines Logo
11:35 am - 11:44 pmPTY-DTW
12h 09m2 stops
United Airlines Logo
6:00 am - 1:55 pmDTW-PTY
7h 55m1 stop
$782United Airlines
Find Deal
mar., mar. 3 - vie., mar. 6
American Airlines Logo
2:30 pm - 9:14 amPTY-DTW
18h 44m2 stops
American Airlines Logo
6:37 pm - 1:10 pmDTW-PTY
18h 33m2 stops
$795American Airlines
Find Deal
mar., mar. 3 - vie., mar. 6

United Airlines flights from Panama City to Detroit

Our best United Airlines deals on Panama City to Detroit flight tickets
United Airlines
Mar 2
PTY4:41 pmPanama City Tocumen Intl
20h 52m
2 stops
DTW1:33 pmDetroit Metropolitan Wayne County
Mar 19
DTW8:15 amDetroit Metropolitan Wayne County
8h 52m
1 stop
PTY4:07 pmPanama City Tocumen Intl
$621
Find similar
United Airlines
Dec 10
PTY4:41 pmPanama City Tocumen Intl
23h 18m
1 stop
DTW3:59 pmDetroit Metropolitan Wayne County
Jan 19
DTW8:15 amDetroit Metropolitan Wayne County
8h 52m
1 stop
PTY5:07 pmPanama City Tocumen Intl
$680
Find similar
United Airlines
Mar 3
PTY11:35 amPanama City Tocumen Intl
12h 09m
2 stops
DTW11:44 pmDetroit Metropolitan Wayne County
Mar 6
DTW6:00 amDetroit Metropolitan Wayne County
7h 55m
1 stop
PTY1:55 pmPanama City Tocumen Intl
$782
Find similar

American Airlines flights from Panama City to Detroit

Our best American Airlines deals on Panama City to Detroit flight tickets
American Airlines
Jan 1
PTY4:56 pmPanama City Tocumen Intl
19h 22m
2 stops
DTW12:18 pmDetroit Metropolitan Wayne County
Jan 30
DTW6:14 amDetroit Metropolitan Wayne County
9h 21m
2 stops
PTY3:35 pmPanama City Tocumen Intl
$757
Find similar
American Airlines
Jan 1
PTY4:56 pmPanama City Tocumen Intl
19h 22m
2 stops
DTW12:18 pmDetroit Metropolitan Wayne County
Jan 30
DTW5:59 amDetroit Metropolitan Wayne County
9h 36m
1 stop
PTY3:35 pmPanama City Tocumen Intl
$758
Find similar
American Airlines
Mar 3
PTY2:30 pmPanama City Tocumen Intl
18h 44m
2 stops
DTW9:14 amDetroit Metropolitan Wayne County
Mar 6
DTW6:37 pmDetroit Metropolitan Wayne County
18h 33m
2 stops
PTY1:10 pmPanama City Tocumen Intl
$795
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Panama City to Detroit that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

mié. 12/10

2:55 pm-2:09 pm

2 stops23h 14m

Detroit Metropolitan Wayne County

lun. 1/19

8:00 am-12:40 am

2 stops16h 40m

$490

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

mar. 12/9

2:55 am-6:26 pm

2 stops15h 31m

Detroit Metropolitan Wayne County

lun. 1/19

6:50 am-12:40 am

2 stops17h 50m

$587

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

mar. 12/9

2:55 am-5:18 pm

3 stops38h 23m

Detroit Metropolitan Wayne County

lun. 1/19

8:00 am-4:55 pm

2 stops32h 55m

$616

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

lun. 3/2

4:41 pm-1:33 pm

2 stops20h 52m

Detroit Metropolitan Wayne County

jue. 3/19

8:15 am-4:07 pm

1 stop8h 52m

$621

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

mié. 12/10

9:33 pm-2:09 pm

1 stop16h 36m

Detroit Metropolitan Wayne County

lun. 1/19

7:00 am-2:00 pm

2 stops31h 00m

$645

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

mié. 12/10

4:41 pm-3:59 pm

1 stop23h 18m

Detroit Metropolitan Wayne County

lun. 1/19

8:15 am-5:07 pm

1 stop8h 52m

$680

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

jue. 1/1

4:56 pm-12:18 pm

2 stops19h 22m

Detroit Metropolitan Wayne County

vie. 1/30

6:14 am-3:35 pm

2 stops9h 21m

$757

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

jue. 1/1

4:56 pm-12:18 pm

2 stops19h 22m

Detroit Metropolitan Wayne County

vie. 1/30

5:59 am-3:35 pm

1 stop9h 36m

$758

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

mar. 3/3

11:35 am-11:44 pm

2 stops12h 09m

Detroit Metropolitan Wayne County

vie. 3/6

6:00 am-1:55 pm

1 stop7h 55m

$782

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

mar. 3/3

2:30 pm-9:14 am

2 stops18h 44m

Detroit Metropolitan Wayne County

vie. 3/6

6:37 pm-1:10 pm

2 stops18h 33m

$795

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Panama City to Detroit

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Detroit?

On average, the least expensive day to fly to Detroit from Panama City is on a Thursday. momondo users have found tickets for Thursday departures for as low as $625. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Panama City to Detroit for around $773.

What is the cheapest time of day to depart on your flight to Detroit?

At noon is the cheapest time of day to fly from Panama City to Detroit when you can find flight prices for as low as $733. Flying to Detroit at noon is an ideal time because this is during off-peak travel hours. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $738 on average. Flights to Detroit from Panama City in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

When to book flights from Panama City to Detroit

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Detroit according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Detroit (PTY to DTT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Detroit

Direct flights

None
There are no direct flights from Panama City to Detroit. There are no popular flight routes from Panama City to Detroit.
Search flight deals

  • How far is Panama City Tocumen Intl to Detroit by plane?

    The straight-line distance from Panama City Tocumen Intl to Detroit is 2312.9 mi. 12h 09m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Detroit?

    Prices for flights from Panama City Tocumen Intl Airport to Detroit are refreshed on a daily basis.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Detroit?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Detroit.

  • What documentation or ID do you need to fly to Detroit?

    The travel and health documents required for your trip to Detroit can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Detroit. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Port Huron
Roseville

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Detroit?

It is quick and easy to find Panama City to Detroit flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Detroit that suits you.

Can I find flights from Panama City to Detroit with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Detroit flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Detroit?

momondo provides multiple filters to help you find the best flight to Detroit from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Detroit right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Detroit flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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