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Cheap flights from Panama City to Detroit from $456

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Detroit departing on 8/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City to Detroit

Cheap round-trip flights

Logo
10:05 pm - 7:54 pmPTY-DTW
20h 49m2 stops
Logo
6:41 am - 9:10 pmDTW-PTY
15h 29m2 stops
$456
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Thu, Aug 28 - Thu, Sep 4
Logo
3:20 am - 8:00 pmPTY-DTW
15h 40m2 stops
Logo
9:19 am - 12:10 amDTW-PTY
15h 51m2 stops
$462
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Wed, Oct 8 - Thu, Oct 16
Logo
3:20 am - 8:00 pmPTY-DTW
15h 40m2 stops
Logo
6:41 am - 9:10 pmDTW-PTY
15h 29m2 stops
$466
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Wed, Sep 3 - Wed, Sep 17
Logo
10:05 pm - 8:00 pmPTY-DTW
20h 55m2 stops
Logo
6:41 am - 9:10 pmDTW-PTY
15h 29m2 stops
$473
Find Deal
Thu, Sep 4 - Wed, Sep 17
Delta Logo
3:17 pm - 9:25 amPTY-DTW
18h 08m1 stop
Delta Logo
12:25 pm - 1:52 pmDTW-PTY
25h 27m1 stop
$600Delta
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Tue, Nov 25 - Wed, Dec 3
Delta Logo
3:17 pm - 11:02 amPTY-DTW
19h 45m1 stop
Delta Logo
12:25 pm - 1:52 pmDTW-PTY
25h 27m1 stop
$627Delta
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Fri, Nov 21 - Wed, Dec 3
American Airlines Logo
2:43 pm - 11:13 amPTY-DTW
20h 30m2 stops
American Airlines Logo
5:22 pm - 1:36 pmDTW-PTY
20h 14m2 stops
$640American Airlines
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Sun, Nov 23 - Mon, Dec 1
American Airlines Logo
2:43 pm - 11:49 pmPTY-DTW
9h 06m1 stop
American Airlines Logo
6:00 am - 1:36 pmDTW-PTY
7h 36m1 stop
$657American Airlines
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Sun, Nov 23 - Mon, Dec 1
United Airlines Logo
3:30 pm - 1:42 pmPTY-DTW
21h 12m1 stop
United Airlines Logo
6:00 am - 6:37 pmDTW-PTY
13h 37m2 stops
$659United Airlines
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Thu, Oct 9 - Thu, Oct 16
United Airlines Logo
8:55 am - 11:42 pmPTY-DTW
14h 47m1 stop
United Airlines Logo
6:00 am - 7:38 pmDTW-PTY
13h 38m2 stops
$667United Airlines
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Mon, Nov 24 - Tue, Dec 2

Delta flights from Panama City to Detroit

Our best Delta deals on Panama City to Detroit flight tickets
Delta
Nov 25
PTY3:17 pmPanama City Tocumen Intl
9h 11m
1 stop
DTW12:28 amDetroit Metropolitan Wayne County
Dec 2
DTW1:35 pmDetroit Metropolitan Wayne County
24h 17m
1 stop
PTY1:52 pmPanama City Tocumen Intl
$600
Find similar
Delta
Nov 21
PTY3:17 pmPanama City Tocumen Intl
19h 45m
1 stop
DTW11:02 amDetroit Metropolitan Wayne County
Dec 3
DTW12:25 pmDetroit Metropolitan Wayne County
25h 27m
1 stop
PTY1:52 pmPanama City Tocumen Intl
$627
Find similar
Delta
Nov 21
PTY3:17 pmPanama City Tocumen Intl
9h 11m
1 stop
DTW12:28 amDetroit Metropolitan Wayne County
Nov 29
DTW9:25 pmDetroit Metropolitan Wayne County
16h 27m
1 stop
PTY1:52 pmPanama City Tocumen Intl
$653
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American Airlines flights from Panama City to Detroit

Our best American Airlines deals on Panama City to Detroit flight tickets
American Airlines
Nov 23
PTY2:43 pmPanama City Tocumen Intl
20h 30m
2 stops
DTW11:13 amDetroit Metropolitan Wayne County
Dec 1
DTW5:22 pmDetroit Metropolitan Wayne County
20h 14m
2 stops
PTY1:36 pmPanama City Tocumen Intl
$640
Find similar
American Airlines
Nov 23
PTY2:43 pmPanama City Tocumen Intl
9h 06m
1 stop
DTW11:49 pmDetroit Metropolitan Wayne County
Dec 1
DTW6:00 amDetroit Metropolitan Wayne County
7h 36m
1 stop
PTY1:36 pmPanama City Tocumen Intl
$657
Find similar
American Airlines
Nov 20
PTY2:43 pmPanama City Tocumen Intl
9h 06m
1 stop
DTW11:49 pmDetroit Metropolitan Wayne County
Dec 1
DTW7:35 pmDetroit Metropolitan Wayne County
18h 01m
2 stops
PTY1:36 pmPanama City Tocumen Intl
$731
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momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 2, 2025.
Use the filters below to find and compare flights from Panama City to Detroit that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 8/28

10:05 pm-7:54 pm

2 stops20h 49m

Detroit Metropolitan Wayne County

Thu 9/4

6:41 am-9:10 pm

2 stops15h 29m

$456

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 10/8

3:20 am-8:00 pm

2 stops15h 40m

Detroit Metropolitan Wayne County

Thu 10/16

9:19 am-12:10 am

2 stops15h 51m

$462

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 9/3

3:20 am-8:00 pm

2 stops15h 40m

Detroit Metropolitan Wayne County

Wed 9/17

6:41 am-9:10 pm

2 stops15h 29m

$466

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 9/4

10:05 pm-8:00 pm

2 stops20h 55m

Detroit Metropolitan Wayne County

Wed 9/17

6:41 am-9:10 pm

2 stops15h 29m

$473

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 11/25

3:17 pm-9:25 am

1 stop18h 08m

Detroit Metropolitan Wayne County

Wed 12/3

12:25 pm-1:52 pm

1 stop25h 27m

$600

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 11/21

3:17 pm-11:02 am

1 stop19h 45m

Detroit Metropolitan Wayne County

Wed 12/3

12:25 pm-1:52 pm

1 stop25h 27m

$627

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sun 11/23

2:43 pm-11:13 am

2 stops20h 30m

Detroit Metropolitan Wayne County

Mon 12/1

5:22 pm-1:36 pm

2 stops20h 14m

$640

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sun 11/23

2:43 pm-11:49 pm

1 stop9h 06m

Detroit Metropolitan Wayne County

Mon 12/1

6:00 am-1:36 pm

1 stop7h 36m

$657

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 10/9

3:30 pm-1:42 pm

1 stop21h 12m

Detroit Metropolitan Wayne County

Thu 10/16

6:00 am-6:37 pm

2 stops13h 37m

$659

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 11/24

8:55 am-11:42 pm

1 stop14h 47m

Detroit Metropolitan Wayne County

Tue 12/2

6:00 am-7:38 pm

2 stops13h 38m

$667

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Panama City to Detroit

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Detroit?

On average, the least expensive day to fly to Detroit from Panama City is on a Thursday. momondo users have found tickets for Thursday departures for as low as $625. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Panama City to Detroit for around $773.

What is the cheapest time of day to depart on your flight to Detroit?

At noon is the cheapest time of day to fly from Panama City to Detroit when you can find flight prices for as low as $733. Flying to Detroit at noon is an ideal time because this is during off-peak travel hours. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $738 on average. Flights to Detroit from Panama City in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

When to book flights from Panama City to Detroit

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Detroit according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Detroit (PTY to DTT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Detroit

Best Price Found

$566

Fastest flight time

9h 05m

Direct flights

None

Airports in Detroit

1 airport
The best one-way flight to Detroit from Panama City in the past 72 hours is $566. The best round-trip flight deal from Panama City to Detroit found on momondo in the last 72 hours is $456.
The fastest flight from Panama City to Detroit takes 9h 05m
There are no direct flights from Panama City to Detroit. Popular non-direct route for this connection is Panama City Tocumen Intl Airport - Detroit Metropolitan Wayne County Airport.
There is 1 airport near Detroit: Detroit Metropolitan Wayne County (DTW)
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  • How far is Panama City Tocumen Intl to Detroit by plane?

    The straight-line distance from Panama City Tocumen Intl to Detroit is 2312.9 mi. 9h 05m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Detroit?

    Prices for flights from Panama City Tocumen Intl Airport to Detroit are refreshed on a daily basis.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Detroit?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Detroit.

  • What documentation or ID do you need to fly to Detroit?

    The travel and health documents required for your trip to Detroit can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Detroit. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Port Huron
Roseville

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Detroit?

It is quick and easy to find Panama City to Detroit flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Detroit that suits you.

Can I find flights from Panama City to Detroit with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Detroit flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Detroit?

momondo provides multiple filters to help you find the best flight to Detroit from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Detroit right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Detroit flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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