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Cheap flights from Panama City to Detroit from $415

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Detroit departing on 2/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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United Airlines Logo
4:41 pm - 3:49 pmPTY-DTW
23h 08m1 stop
United Airlines Logo
5:50 pm - 5:07 pmDTW-PTY
23h 17m2 stops
$707United Airlines
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Thu, Jan 1 - Fri, Jan 30
United Airlines Logo
8:55 am - 10:30 pmPTY-DTW
13h 35m2 stops
United Airlines Logo
5:50 pm - 2:45 pmDTW-PTY
20h 55m2 stops
$755United Airlines
Find Deal
Thu, Jan 1 - Fri, Jan 30
United Airlines Logo
10:00 am - 11:44 pmPTY-DTW
12h 44m1 stop
United Airlines Logo
12:11 pm - 7:31 pmDTW-PTY
8h 20m1 stop
$791United Airlines
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Fri, Apr 24 - Tue, Apr 28
United Airlines Logo
7:55 am - 11:44 pmPTY-DTW
14h 49m1 stop
United Airlines Logo
2:15 pm - 4:04 amDTW-PTY
14h 49m2 stops
$796United Airlines
Find Deal
Fri, Apr 24 - Tue, Apr 28
Delta Logo
2:20 pm - 9:24 amPTY-DTW
18h 04m1 stop
Delta Logo
7:45 pm - 12:55 pmDTW-PTY
18h 10m1 stop
$802Delta
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Fri, Apr 24 - Tue, Apr 28
American Airlines Logo
1:55 pm - 8:53 amPTY-DTW
17h 58m2 stops
American Airlines Logo
5:52 pm - 12:15 pmDTW-PTY
19h 23m2 stops
$887American Airlines
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Fri, Apr 24 - Tue, Apr 28
American Airlines Logo
2:53 pm - 11:57 pmPTY-DTW
9h 04m1 stop
American Airlines Logo
5:30 am - 3:38 pmDTW-PTY
10h 08m1 stop
$891American Airlines
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Thu, Jan 1 - Fri, Jan 30
American Airlines Logo
2:53 pm - 11:57 pmPTY-DTW
9h 04m1 stop
American Airlines Logo
6:00 am - 3:38 pmDTW-PTY
9h 38m2 stops
$895American Airlines
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Thu, Jan 1 - Fri, Jan 30
Delta Logo
3:37 pm - 8:00 amPTY-DTW
16h 23m1 stop
Delta Logo
8:05 am - 7:59 pmDTW-PTY
11h 54m1 stop
$985Delta
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Mon, Nov 24 - Sat, Nov 29
Delta Logo
3:37 pm - 8:00 amPTY-DTW
16h 23m1 stop
Delta Logo
5:45 am - 7:59 pmDTW-PTY
14h 14m1 stop
$1,060Delta
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Mon, Nov 24 - Sat, Nov 29

United Airlines flights from Panama City to Detroit Metropolitan Wayne County Airport

Our best United Airlines deals on Panama City to Detroit Metropolitan Wayne County Airport flight tickets
United Airlines
Jan 1
PTY4:41 pmPanama City Tocumen Intl
23h 08m
1 stop
DTW3:49 pmDetroit Metropolitan Wayne County
Jan 30
DTW5:50 pmDetroit Metropolitan Wayne County
23h 17m
2 stops
PTY5:07 pmPanama City Tocumen Intl
$707
Find similar
United Airlines
Jan 1
PTY8:55 amPanama City Tocumen Intl
13h 35m
2 stops
DTW10:30 pmDetroit Metropolitan Wayne County
Jan 30
DTW5:50 pmDetroit Metropolitan Wayne County
20h 55m
2 stops
PTY2:45 pmPanama City Tocumen Intl
$755
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United Airlines
Apr 24
PTY10:00 amPanama City Tocumen Intl
12h 44m
1 stop
DTW11:44 pmDetroit Metropolitan Wayne County
Apr 28
DTW12:11 pmDetroit Metropolitan Wayne County
8h 20m
1 stop
PTY7:31 pmPanama City Tocumen Intl
$791
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American Airlines flights from Panama City to Detroit Metropolitan Wayne County Airport

Our best American Airlines deals on Panama City to Detroit Metropolitan Wayne County Airport flight tickets
American Airlines
Apr 24
PTY1:55 pmPanama City Tocumen Intl
17h 58m
2 stops
DTW8:53 amDetroit Metropolitan Wayne County
Apr 28
DTW5:52 pmDetroit Metropolitan Wayne County
19h 23m
2 stops
PTY12:15 pmPanama City Tocumen Intl
$887
Find similar
American Airlines
Jan 1
PTY2:53 pmPanama City Tocumen Intl
9h 04m
1 stop
DTW11:57 pmDetroit Metropolitan Wayne County
Jan 30
DTW5:30 amDetroit Metropolitan Wayne County
10h 08m
1 stop
PTY3:38 pmPanama City Tocumen Intl
$891
Find similar
American Airlines
Jan 1
PTY2:53 pmPanama City Tocumen Intl
9h 04m
1 stop
DTW11:57 pmDetroit Metropolitan Wayne County
Jan 30
DTW6:00 amDetroit Metropolitan Wayne County
9h 38m
2 stops
PTY3:38 pmPanama City Tocumen Intl
$895
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momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Panama City to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/1

4:41 pm-3:49 pm

1 stop23h 08m

Detroit Metropolitan Wayne County

Fri 1/30

5:50 pm-5:07 pm

2 stops23h 17m

$707

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/1

8:55 am-10:30 pm

2 stops13h 35m

Detroit Metropolitan Wayne County

Fri 1/30

5:50 pm-2:45 pm

2 stops20h 55m

$755

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 4/24

10:00 am-11:44 pm

1 stop12h 44m

Detroit Metropolitan Wayne County

Tue 4/28

12:11 pm-7:31 pm

1 stop8h 20m

$791

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 4/24

7:55 am-11:44 pm

1 stop14h 49m

Detroit Metropolitan Wayne County

Tue 4/28

2:15 pm-4:04 am

2 stops14h 49m

$796

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 4/24

2:20 pm-9:24 am

1 stop18h 04m

Detroit Metropolitan Wayne County

Tue 4/28

7:45 pm-12:55 pm

1 stop18h 10m

$802

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 4/24

1:55 pm-8:53 am

2 stops17h 58m

Detroit Metropolitan Wayne County

Tue 4/28

5:52 pm-12:15 pm

2 stops19h 23m

$887

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/1

2:53 pm-11:57 pm

1 stop9h 04m

Detroit Metropolitan Wayne County

Fri 1/30

5:30 am-3:38 pm

1 stop10h 08m

$891

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/1

2:53 pm-11:57 pm

1 stop9h 04m

Detroit Metropolitan Wayne County

Fri 1/30

6:00 am-3:38 pm

2 stops9h 38m

$895

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 11/24

3:37 pm-8:00 am

1 stop16h 23m

Detroit Metropolitan Wayne County

Sat 11/29

8:05 am-7:59 pm

1 stop11h 54m

$985

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 11/24

3:37 pm-8:00 am

1 stop16h 23m

Detroit Metropolitan Wayne County

Sat 11/29

5:45 am-7:59 pm

1 stop14h 14m

$1,060

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Panama City to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Panama City to Detroit Metropolitan Wayne County Airport is on a Monday when prices can be found for as low as $801. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Sunday is $1,008.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Panama City in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $781 when looking at flights departing in the afternoon. Flights to Detroit Metropolitan Wayne County Airport are more costly in the morning, with an average ticket price of $1,008. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Panama City to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Detroit Metropolitan Wayne County Airport (PTY to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Detroit Metropolitan Wayne County Airport

Direct flights

None
There are no direct flights from Panama City to Detroit Metropolitan Wayne County Airport. There are no popular flight routes from Panama City to Detroit Metropolitan Wayne County Airport.
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  • How far is Panama City Tocumen Intl to Detroit Metropolitan Wayne County by plane?

    Detroit Metropolitan Wayne County is 2306.7 mi away from Panama City Tocumen Intl. By plane, this route typically takes 9h 04m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The travel and health documents required for your trip to Detroit Metropolitan Wayne County Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Detroit Metropolitan Wayne County Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Southfield
Troy
Dearborn
Romulus
Monroe
Novi
Livonia
Port Clinton
Port Huron
Roseville
Sterling Heights
Brighton
Ypsilanti
Pontiac
Dundee
Madison Heights
Royal Oak

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Detroit?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Detroit. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Detroit with flexible booking policies on momondo?

Flights from Panama City to Detroit with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Detroit?

Once all potential Panama City to Detroit flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Detroit right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Detroit from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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