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Cheap flights from Panama City to Detroit from $287

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Detroit departing on 5/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:10 am - 7:02 pm
PTY
-
DTW
31h 52m
3 stops
Multiple Airlines Logo
6:50 am - 2:15 pm
DTW
-
PTY
32h 25m
3 stops
$555Multiple Airlines
Wed, Apr 15 - Tue, Apr 21
Multiple Airlines Logo
4:25 am - 11:59 pm
PTY
-
DTW
18h 34m
2 stops
Multiple Airlines Logo
6:50 am - 9:15 am
DTW
-
PTY
27h 25m
3 stops
$599Multiple Airlines
Wed, Apr 15 - Tue, Apr 21
Multiple Airlines Logo
4:25 am - 11:59 pm
PTY
-
DTW
18h 34m
2 stops
Multiple Airlines Logo
6:10 am - 12:35 am
DTW
-
PTY
19h 25m
2 stops
$619Multiple Airlines
Wed, Apr 15 - Tue, Apr 21
Multiple Airlines Logo
3:10 pm - 11:59 pm
PTY
-
DTW
31h 49m
2 stops
Multiple Airlines Logo
8:30 pm - 12:35 am
DTW
-
PTY
29h 05m
3 stops
$629Multiple Airlines
Thu, Apr 16 - Sun, Apr 19
Multiple Airlines Logo
10:10 am - 7:02 pm
PTY
-
DTW
31h 52m
3 stops
Multiple Airlines Logo
8:30 pm - 12:35 am
DTW
-
PTY
29h 05m
3 stops
$632Multiple Airlines
Thu, Apr 16 - Sun, Apr 19
Multiple Airlines Logo
4:25 am - 11:59 pm
PTY
-
DTW
18h 34m
2 stops
Multiple Airlines Logo
6:50 am - 9:15 am
DTW
-
PTY
27h 25m
3 stops
$639Multiple Airlines
Sat, Apr 18 - Sat, Apr 25
Multiple Airlines Logo
3:10 pm - 11:59 pm
PTY
-
DTW
31h 49m
2 stops
Multiple Airlines Logo
6:10 am - 5:00 pm
DTW
-
PTY
35h 50m
2 stops
$641Multiple Airlines
Thu, Apr 16 - Sun, Apr 19
Multiple Airlines Logo
3:10 pm - 11:53 pm
PTY
-
DTW
31h 43m
2 stops
Multiple Airlines Logo
5:00 am - 2:15 pm
DTW
-
PTY
34h 15m
2 stops
$650Multiple Airlines
Fri, May 22 - Fri, May 29
Multiple Airlines Logo
4:25 am - 11:53 pm
PTY
-
DTW
18h 28m
2 stops
Multiple Airlines Logo
6:00 am - 12:35 am
DTW
-
PTY
19h 35m
2 stops
$654Multiple Airlines
Wed, May 20 - Wed, Jun 10
Multiple Airlines Logo
4:25 am - 8:02 am
PTY
-
DTW
26h 37m
3 stops
Multiple Airlines Logo
8:25 am - 2:15 pm
DTW
-
PTY
30h 50m
3 stops
$659Multiple Airlines
Sat, Apr 25 - Wed, Apr 29

Avianca flights from Panama City to Detroit Metropolitan Wayne County Airport

Our best Avianca deals on Panama City to Detroit Metropolitan Wayne County Airport flight tickets
Avianca
Apr 16
PTY11:25 amPanama City Tocumen Intl
21h 49m
3 stops
DTW10:14 amDetroit Metropolitan Wayne County
Apr 20
DTW7:47 pmDetroit Metropolitan Wayne County
15h 43m
2 stops
PTY10:30 amPanama City Tocumen Intl
$1,101
Avianca
Apr 16
PTY11:25 amPanama City Tocumen Intl
21h 49m
3 stops
DTW10:14 amDetroit Metropolitan Wayne County
Apr 20
DTW7:47 pmDetroit Metropolitan Wayne County
20h 08m
3 stops
PTY2:55 pmPanama City Tocumen Intl
$1,108
Avianca
Apr 16
PTY11:25 amPanama City Tocumen Intl
21h 49m
3 stops
DTW10:14 amDetroit Metropolitan Wayne County
Apr 18
DTW1:45 pmDetroit Metropolitan Wayne County
13h 10m
2 stops
PTY1:55 amPanama City Tocumen Intl
$1,139

United Airlines flights from Panama City to Detroit Metropolitan Wayne County Airport

Our best United Airlines deals on Panama City to Detroit Metropolitan Wayne County Airport flight tickets
United Airlines
Jun 17
PTY3:30 pmPanama City Tocumen Intl
17h 22m
2 stops
DTW9:52 amDetroit Metropolitan Wayne County
Jul 7
DTW6:15 amDetroit Metropolitan Wayne County
8h 59m
1 stop
PTY2:14 pmPanama City Tocumen Intl
$823
United Airlines
Apr 16
PTY10:00 amPanama City Tocumen Intl
12h 57m
1 stop
DTW11:57 pmDetroit Metropolitan Wayne County
Apr 20
DTW9:00 amDetroit Metropolitan Wayne County
10h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$1,327
United Airlines
Apr 16
PTY10:00 amPanama City Tocumen Intl
14h 16m
2 stops
DTW1:16 amDetroit Metropolitan Wayne County
Apr 20
DTW7:18 amDetroit Metropolitan Wayne County
12h 19m
2 stops
PTY6:37 pmPanama City Tocumen Intl
$1,332

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 11, 2026.
Use the filters below to find and compare flights from Panama City to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 4/15

10:10 am-7:02 pm

3 stops31h 52m

Detroit Metropolitan Wayne County

Tue 4/21

6:50 am-2:15 pm

3 stops32h 25m

$555

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 4/15

4:25 am-11:59 pm

2 stops18h 34m

Detroit Metropolitan Wayne County

Tue 4/21

6:50 am-9:15 am

3 stops27h 25m

$599
Quickest round-trip

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 4/15

4:25 am-11:59 pm

2 stops18h 34m

Detroit Metropolitan Wayne County

Tue 4/21

6:10 am-12:35 am

2 stops19h 25m

$619

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 4/16

3:10 pm-11:59 pm

2 stops31h 49m

Detroit Metropolitan Wayne County

Sun 4/19

8:30 pm-12:35 am

3 stops29h 05m

$629

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 4/16

10:10 am-7:02 pm

3 stops31h 52m

Detroit Metropolitan Wayne County

Sun 4/19

8:30 pm-12:35 am

3 stops29h 05m

$632

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 4/18

4:25 am-11:59 pm

2 stops18h 34m

Detroit Metropolitan Wayne County

Sat 4/25

6:50 am-9:15 am

3 stops27h 25m

$639

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 4/16

3:10 pm-11:59 pm

2 stops31h 49m

Detroit Metropolitan Wayne County

Sun 4/19

6:10 am-5:00 pm

2 stops35h 50m

$641

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 5/22

3:10 pm-11:53 pm

2 stops31h 43m

Detroit Metropolitan Wayne County

Fri 5/29

5:00 am-2:15 pm

2 stops34h 15m

$650

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 5/20

4:25 am-11:53 pm

2 stops18h 28m

Detroit Metropolitan Wayne County

Wed 6/10

6:00 am-12:35 am

2 stops19h 35m

$654

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 4/25

4:25 am-8:02 am

3 stops26h 37m

Detroit Metropolitan Wayne County

Wed 4/29

8:25 am-2:15 pm

3 stops30h 50m

$659

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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When to book flights from Panama City to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Detroit Metropolitan Wayne County Airport (PTY to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Detroit Metropolitan Wayne County Airport

Fastest flight time

9h 59m

Direct flights

None
The fastest flight from Panama City to Detroit Metropolitan Wayne County Airport takes 9h 59m
There are no direct flights from Panama City to Detroit Metropolitan Wayne County Airport. There are no popular flight routes from Panama City to Detroit Metropolitan Wayne County Airport.
Search flight deals

Frequently asked questions about flying from Panama City to Detroit Metropolitan Wayne County Airport

  • How far is Panama City Tocumen Intl to Detroit Metropolitan Wayne County by plane?

    Detroit Metropolitan Wayne County is 2306.7 mi away from Panama City Tocumen Intl. By plane, this route typically takes 9h 59m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The travel and health documents required for your trip to Detroit Metropolitan Wayne County Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Detroit Metropolitan Wayne County Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Frequently asked questions about flying from Panama City to Detroit Metropolitan Wayne County Airport

  • How do I get Price Alerts for flights from Panama City to Detroit Metropolitan Wayne County Airport?

    Search flight deals from Panama City to Detroit Metropolitan Wayne County Airport. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Panama City to Detroit Metropolitan Wayne County Airport with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    We aggregate our prices from over 700+ competitors from airlines to OTAs. We operate in over 30 markets worldwide to show you a wide range of travel options.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Dearborn
Romulus
Troy
Monroe
Southfield
Livonia
Novi
Port Clinton
Roseville
Sterling Heights
Port Huron
Dundee
Brighton
Ypsilanti
Pontiac
Farmington Hills
Plymouth

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Detroit?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Detroit. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Detroit with flexible booking policies on momondo?

Flights from Panama City to Detroit with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Detroit?

Once all potential Panama City to Detroit flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Detroit right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Detroit from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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