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Cheap flights from Panama City to Detroit from $241

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Detroit departing on 3/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:10 am - 10:37 pm
PTY
-
DTW
35h 27m
3 stops
Multiple Airlines Logo
6:30 am - 2:15 pm
DTW
-
PTY
32h 45m
3 stops
$477Multiple Airlines
Mon, Apr 13 - Mon, Apr 20
Multiple Airlines Logo
3:10 pm - 11:59 pm
PTY
-
DTW
31h 49m
2 stops
Multiple Airlines Logo
6:30 am - 9:15 am
DTW
-
PTY
27h 45m
3 stops
$487Multiple Airlines
Mon, Apr 13 - Mon, Apr 20
Multiple Airlines Logo
6:15 pm - 12:20 pm
PTY
-
DTW
17h 05m
1 stop
Multiple Airlines Logo
6:30 am - 5:00 pm
DTW
-
PTY
35h 30m
3 stops
$507Multiple Airlines
Mon, Apr 13 - Mon, Apr 20
Multiple Airlines Logo
3:25 am - 12:19 am
PTY
-
DTW
19h 54m
3 stops
Multiple Airlines Logo
1:57 pm - 5:00 pm
DTW
-
PTY
28h 03m
3 stops
$515Multiple Airlines
Tue, Apr 14 - Wed, Apr 22
Multiple Airlines Logo
3:25 am - 12:19 am
PTY
-
DTW
19h 54m
3 stops
Multiple Airlines Logo
5:00 am - 1:05 am
DTW
-
PTY
21h 05m
2 stops
$516Multiple Airlines
Tue, Apr 14 - Wed, Apr 22
Multiple Airlines Logo
9:33 pm - 6:44 pm
PTY
-
DTW
20h 11m
1 stop
Multiple Airlines Logo
12:33 pm - 8:06 am
DTW
-
PTY
20h 33m
2 stops
$519Multiple Airlines
Wed, Apr 15 - Wed, Apr 22
Multiple Airlines Logo
12:15 pm - 12:38 am
PTY
-
DTW
11h 23m
1 stop
Multiple Airlines Logo
4:14 pm - 1:05 am
DTW
-
PTY
33h 51m
2 stops
$550Multiple Airlines
Thu, May 14 - Mon, May 18
Multiple Airlines Logo
3:25 am - 11:59 pm
PTY
-
DTW
19h 34m
2 stops
Multiple Airlines Logo
5:00 am - 1:05 am
DTW
-
PTY
21h 05m
2 stops
$555Multiple Airlines
Tue, Apr 14 - Wed, Apr 22
Multiple Airlines Logo
3:05 am - 9:38 pm
PTY
-
DTW
17h 33m
2 stops
Multiple Airlines Logo
5:00 am - 1:05 am
DTW
-
PTY
21h 05m
2 stops
$586Multiple Airlines
Wed, May 13 - Mon, May 18
Multiple Airlines Logo
9:33 pm - 6:44 pm
PTY
-
DTW
20h 11m
1 stop
Multiple Airlines Logo
7:04 pm - 8:34 pm
DTW
-
PTY
26h 30m
1 stop
$612Multiple Airlines
Wed, Apr 15 - Wed, Apr 22

Copa Airlines flights from Panama City to Detroit Metropolitan Wayne County Airport

Our best Copa Airlines deals on Panama City to Detroit Metropolitan Wayne County Airport flight tickets
Copa Airlines
Jun 12
PTY10:10 pmPanama City Tocumen Intl
10h 48m
1 stop
DTW9:58 amDetroit Metropolitan Wayne County
Jul 6
DTW11:05 amDetroit Metropolitan Wayne County
10h 36m
1 stop
PTY8:41 pmPanama City Tocumen Intl
$744
Copa Airlines
Jun 17
PTY10:10 pmPanama City Tocumen Intl
10h 42m
1 stop
DTW9:52 amDetroit Metropolitan Wayne County
Jul 7
DTW10:13 amDetroit Metropolitan Wayne County
11h 22m
1 stop
PTY8:35 pmPanama City Tocumen Intl
$760

American Airlines flights from Panama City to Detroit Metropolitan Wayne County Airport

Our best American Airlines deals on Panama City to Detroit Metropolitan Wayne County Airport flight tickets
American Airlines
Jun 12
PTY1:14 pmPanama City Tocumen Intl
9h 41m
1 stop
DTW11:55 pmDetroit Metropolitan Wayne County
Jul 6
DTW5:27 pmDetroit Metropolitan Wayne County
19h 43m
2 stops
PTY12:10 pmPanama City Tocumen Intl
$914
American Airlines
Jun 12
PTY1:14 pmPanama City Tocumen Intl
9h 41m
1 stop
DTW11:55 pmDetroit Metropolitan Wayne County
Jul 6
DTW6:00 amDetroit Metropolitan Wayne County
7h 10m
1 stop
PTY12:10 pmPanama City Tocumen Intl
$931

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Panama City to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 4/13

10:10 am-10:37 pm

3 stops35h 27m

Detroit Metropolitan Wayne County

Mon 4/20

6:30 am-2:15 pm

3 stops32h 45m

$477

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 4/13

3:10 pm-11:59 pm

2 stops31h 49m

Detroit Metropolitan Wayne County

Mon 4/20

6:30 am-9:15 am

3 stops27h 45m

$487

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 4/13

6:15 pm-12:20 pm

1 stop17h 05m

Detroit Metropolitan Wayne County

Mon 4/20

6:30 am-5:00 pm

3 stops35h 30m

$507

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 4/14

3:25 am-12:19 am

3 stops19h 54m

Detroit Metropolitan Wayne County

Wed 4/22

1:57 pm-5:00 pm

3 stops28h 03m

$515

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 4/14

3:25 am-12:19 am

3 stops19h 54m

Detroit Metropolitan Wayne County

Wed 4/22

5:00 am-1:05 am

2 stops21h 05m

$516

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 4/15

9:33 pm-6:44 pm

1 stop20h 11m

Detroit Metropolitan Wayne County

Wed 4/22

12:33 pm-8:06 am

2 stops20h 33m

$519

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 5/14

12:15 pm-12:38 am

1 stop11h 23m

Detroit Metropolitan Wayne County

Mon 5/18

4:14 pm-1:05 am

2 stops33h 51m

$550

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 4/14

3:25 am-11:59 pm

2 stops19h 34m

Detroit Metropolitan Wayne County

Wed 4/22

5:00 am-1:05 am

2 stops21h 05m

$555

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 5/13

3:05 am-9:38 pm

2 stops17h 33m

Detroit Metropolitan Wayne County

Mon 5/18

5:00 am-1:05 am

2 stops21h 05m

$586

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 4/15

9:33 pm-6:44 pm

1 stop20h 11m

Detroit Metropolitan Wayne County

Wed 4/22

7:04 pm-8:34 pm

1 stop26h 30m

$612

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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When to book flights from Panama City to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Detroit Metropolitan Wayne County Airport (PTY to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Detroit Metropolitan Wayne County Airport

Fastest flight time

10h 48m

Direct flights

None
The fastest flight from Panama City to Detroit Metropolitan Wayne County Airport takes 10h 48m
There are no direct flights from Panama City to Detroit Metropolitan Wayne County Airport. There are no popular flight routes from Panama City to Detroit Metropolitan Wayne County Airport.
Search flight deals

  • How far is Panama City Tocumen Intl to Detroit Metropolitan Wayne County by plane?

    Detroit Metropolitan Wayne County is 2306.7 mi away from Panama City Tocumen Intl. By plane, this route typically takes 10h 48m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The travel and health documents required for your trip to Detroit Metropolitan Wayne County Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Detroit Metropolitan Wayne County Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • How do I get Price Alerts for flights from Panama City to Detroit Metropolitan Wayne County Airport?

    Search flight deals from Panama City to Detroit Metropolitan Wayne County Airport. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Panama City to Detroit Metropolitan Wayne County Airport with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    We aggregate our prices from over 700+ competitors from airlines to OTAs. We operate in over 30 markets worldwide to show you a wide range of travel options.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Troy
Dearborn
Romulus
Southfield
Monroe
Novi
Livonia
Port Clinton
Roseville
Port Huron
Sterling Heights
Brighton
Dundee
Ypsilanti
Pontiac
Southgate
Plymouth

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Detroit?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Detroit. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Detroit with flexible booking policies on momondo?

Flights from Panama City to Detroit with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Detroit?

Once all potential Panama City to Detroit flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Detroit right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Detroit from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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