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Cheap flights from Panama City to Detroit from $266

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Detroit departing on 8/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City to Detroit

Cheap round-trip flights

Logo
10:05 pm - 7:54 pmPTY-DTW
20h 49m2 stops
Logo
6:41 am - 9:10 pmDTW-PTY
15h 29m2 stops
$456
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Thu, Aug 28 - Thu, Sep 4
Logo
10:05 pm - 8:00 pmPTY-DTW
20h 55m2 stops
Logo
6:41 am - 12:45 amDTW-PTY
19h 04m2 stops
$457
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Fri, Sep 12 - Fri, Sep 19
Logo
3:20 am - 8:00 pmPTY-DTW
15h 40m2 stops
Logo
9:19 am - 12:10 amDTW-PTY
15h 51m2 stops
$462
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Wed, Oct 8 - Thu, Oct 16
Logo
3:20 am - 8:00 pmPTY-DTW
15h 40m2 stops
Logo
6:41 am - 9:10 pmDTW-PTY
15h 29m2 stops
$466
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Wed, Sep 3 - Wed, Sep 17
Logo
10:05 pm - 8:00 pmPTY-DTW
20h 55m2 stops
Logo
6:41 am - 9:10 pmDTW-PTY
15h 29m2 stops
$473
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Thu, Sep 4 - Wed, Sep 17
United Airlines Logo
3:30 pm - 1:42 pmPTY-DTW
21h 12m1 stop
United Airlines Logo
6:00 am - 6:37 pmDTW-PTY
13h 37m2 stops
$659United Airlines
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Thu, Oct 9 - Thu, Oct 16
United Airlines Logo
9:45 am - 9:13 pmPTY-DTW
10h 28m1 stop
United Airlines Logo
8:30 am - 6:37 pmDTW-PTY
11h 07m1 stop
$775United Airlines
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Thu, Oct 9 - Thu, Oct 16
Copa Airlines Logo
9:13 am - 7:04 pmPTY-DTW
9h 51m1 stop
Copa Airlines Logo
7:44 pm - 6:13 amDTW-PTY
10h 29m1 stop
$914Copa Airlines
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Thu, Jan 1 - Fri, Jan 30
American Airlines Logo
2:40 pm - 10:43 amPTY-DTW
20h 03m2 stops
American Airlines Logo
6:40 pm - 1:10 pmDTW-PTY
18h 30m2 stops
$959American Airlines
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Thu, Jan 1 - Fri, Jan 30
American Airlines Logo
4:45 pm - 2:45 pmPTY-DTW
22h 00m2 stops
American Airlines Logo
6:40 pm - 3:35 pmDTW-PTY
20h 55m2 stops
$961American Airlines
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Thu, Jan 1 - Fri, Jan 30

American Airlines flights from Panama City to Detroit Metropolitan Wayne County Airport

Our best American Airlines deals on Panama City to Detroit Metropolitan Wayne County Airport flight tickets
American Airlines
Jan 1
PTY2:40 pmPanama City Tocumen Intl
20h 03m
2 stops
DTW10:43 amDetroit Metropolitan Wayne County
Jan 30
DTW6:40 pmDetroit Metropolitan Wayne County
18h 30m
2 stops
PTY1:10 pmPanama City Tocumen Intl
$959
Find similar
American Airlines
Jan 1
PTY4:45 pmPanama City Tocumen Intl
22h 00m
2 stops
DTW2:45 pmDetroit Metropolitan Wayne County
Jan 30
DTW6:40 pmDetroit Metropolitan Wayne County
20h 55m
2 stops
PTY3:35 pmPanama City Tocumen Intl
$961
Find similar
American Airlines
Jan 1
PTY4:45 pmPanama City Tocumen Intl
22h 00m
2 stops
DTW2:45 pmDetroit Metropolitan Wayne County
Jan 30
DTW7:22 pmDetroit Metropolitan Wayne County
20h 13m
2 stops
PTY3:35 pmPanama City Tocumen Intl
$962
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United Airlines flights from Panama City to Detroit Metropolitan Wayne County Airport

Our best United Airlines deals on Panama City to Detroit Metropolitan Wayne County Airport flight tickets
United Airlines
Oct 9
PTY3:30 pmPanama City Tocumen Intl
21h 12m
1 stop
DTW1:42 pmDetroit Metropolitan Wayne County
Oct 16
DTW6:00 amDetroit Metropolitan Wayne County
13h 37m
2 stops
PTY6:37 pmPanama City Tocumen Intl
$659
Find similar
United Airlines
Oct 9
PTY9:45 amPanama City Tocumen Intl
10h 28m
1 stop
DTW9:13 pmDetroit Metropolitan Wayne County
Oct 16
DTW8:30 amDetroit Metropolitan Wayne County
11h 07m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$775
Find similar
United Airlines
Jan 1
PTY4:41 pmPanama City Tocumen Intl
17h 52m
2 stops
DTW10:33 amDetroit Metropolitan Wayne County
Jan 30
DTW8:15 amDetroit Metropolitan Wayne County
11h 23m
1 stop
PTY7:38 pmPanama City Tocumen Intl
$1,020
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momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Panama City to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 8/28

10:05 pm-7:54 pm

2 stops20h 49m

Detroit Metropolitan Wayne County

Thu 9/4

6:41 am-9:10 pm

2 stops15h 29m

$456

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 9/12

10:05 pm-8:00 pm

2 stops20h 55m

Detroit Metropolitan Wayne County

Fri 9/19

6:41 am-12:45 am

2 stops19h 04m

$457

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 10/8

3:20 am-8:00 pm

2 stops15h 40m

Detroit Metropolitan Wayne County

Thu 10/16

9:19 am-12:10 am

2 stops15h 51m

$462

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 9/3

3:20 am-8:00 pm

2 stops15h 40m

Detroit Metropolitan Wayne County

Wed 9/17

6:41 am-9:10 pm

2 stops15h 29m

$466

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 9/4

10:05 pm-8:00 pm

2 stops20h 55m

Detroit Metropolitan Wayne County

Wed 9/17

6:41 am-9:10 pm

2 stops15h 29m

$473

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 10/9

3:30 pm-1:42 pm

1 stop21h 12m

Detroit Metropolitan Wayne County

Thu 10/16

6:00 am-6:37 pm

2 stops13h 37m

$659

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 10/9

9:45 am-9:13 pm

1 stop10h 28m

Detroit Metropolitan Wayne County

Thu 10/16

8:30 am-6:37 pm

1 stop11h 07m

$775

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/1

9:13 am-7:04 pm

1 stop9h 51m

Detroit Metropolitan Wayne County

Fri 1/30

7:44 pm-6:13 am

1 stop10h 29m

$914

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/1

2:40 pm-10:43 am

2 stops20h 03m

Detroit Metropolitan Wayne County

Fri 1/30

6:40 pm-1:10 pm

2 stops18h 30m

$959

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/1

4:45 pm-2:45 pm

2 stops22h 00m

Detroit Metropolitan Wayne County

Fri 1/30

6:40 pm-3:35 pm

2 stops20h 55m

$961

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Panama City to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Detroit Metropolitan Wayne County Airport?

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Panama City to Detroit Metropolitan Wayne County Airport is on a Monday when prices can be found for as low as $801. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Sunday is $1,008.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Panama City in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $781 when looking at flights departing in the afternoon. Flights to Detroit Metropolitan Wayne County Airport are more costly in the morning, with an average ticket price of $1,008. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Panama City to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Detroit Metropolitan Wayne County Airport (PTY to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Detroit Metropolitan Wayne County Airport

Best Price Found

$266

Fastest flight time

9h 51m

Direct flights

None
The best one-way flight to Detroit Metropolitan Wayne County Airport from Panama City in the past 72 hours is $266. The best round-trip flight deal from Panama City to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $456.
The fastest flight from Panama City to Detroit Metropolitan Wayne County Airport takes 9h 51m
There are no direct flights from Panama City to Detroit Metropolitan Wayne County Airport. Popular non-direct route for this connection is Panama City Tocumen Intl Airport - Detroit Metropolitan Wayne County Airport.
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  • How far is Panama City Tocumen Intl to Detroit Metropolitan Wayne County by plane?

    Detroit Metropolitan Wayne County is 2306.7 mi away from Panama City Tocumen Intl. By plane, this route typically takes 9h 51m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The travel and health documents required for your trip to Detroit Metropolitan Wayne County Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Detroit Metropolitan Wayne County Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Southfield
Warren
Monroe
Troy
Livonia
Novi
Dearborn
Romulus
Port Huron
Port Clinton
Sterling Heights
Roseville
Brighton
Madison Heights
Pontiac
Ypsilanti
Belleville
Farmington Hills

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Detroit?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Detroit. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Detroit with flexible booking policies on momondo?

Flights from Panama City to Detroit with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Detroit?

Once all potential Panama City to Detroit flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Detroit right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Detroit from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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