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Cheap flights from Panama City to Detroit from $331

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Detroit departing on 7/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Panama City to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:30 am - 1:04 am
PTY
-
DTW
18h 34m
3 stops
Multiple Airlines Logo
6:00 am - 12:35 am
DTW
-
PTY
19h 35m
3 stops
$626Multiple Airlines
Fri, Aug 21 - Fri, Aug 28
Multiple Airlines Logo
10:10 am - 5:22 pm
PTY
-
DTW
30h 12m
2 stops
Multiple Airlines Logo
11:00 am - 8:19 pm
DTW
-
PTY
10h 19m
1 stop
$635Multiple Airlines
Tue, Aug 25 - Tue, Oct 6
Multiple Airlines Logo
3:50 pm - 11:59 pm
PTY
-
DTW
31h 09m
2 stops
Multiple Airlines Logo
5:30 pm - 10:30 am
DTW
-
PTY
18h 00m
2 stops
$669Multiple Airlines
Tue, Aug 25 - Fri, Sep 25
Multiple Airlines Logo
3:50 pm - 11:59 pm
PTY
-
DTW
31h 09m
2 stops
Multiple Airlines Logo
5:30 pm - 2:55 pm
DTW
-
PTY
22h 25m
3 stops
$676Multiple Airlines
Tue, Aug 18 - Fri, Oct 9
Multiple Airlines Logo
10:10 am - 5:22 pm
PTY
-
DTW
30h 12m
2 stops
Multiple Airlines Logo
11:00 am - 8:19 pm
DTW
-
PTY
10h 19m
1 stop
$681Multiple Airlines
Tue, Aug 25 - Fri, Sep 25
Multiple Airlines Logo
10:10 am - 12:55 pm
PTY
-
DTW
25h 45m
2 stops
Multiple Airlines Logo
11:00 am - 8:19 pm
DTW
-
PTY
10h 19m
1 stop
$687Multiple Airlines
Wed, Aug 5 - Tue, Oct 13
Multiple Airlines Logo
10:10 am - 5:22 pm
PTY
-
DTW
30h 12m
2 stops
Multiple Airlines Logo
8:46 pm - 8:31 pm
DTW
-
PTY
24h 45m
1 stop
$703Multiple Airlines
Fri, Aug 21 - Fri, Aug 28
Multiple Airlines Logo
12:03 pm - 5:22 pm
PTY
-
DTW
28h 19m
1 stop
Multiple Airlines Logo
11:00 am - 8:19 pm
DTW
-
PTY
10h 19m
1 stop
$718Multiple Airlines
Tue, Aug 25 - Tue, Oct 6
Multiple Airlines Logo
10:00 am - 1:04 am
PTY
-
DTW
14h 04m
1 stop
Multiple Airlines Logo
3:38 pm - 4:06 pm
DTW
-
PTY
25h 28m
2 stops
$728Multiple Airlines
Tue, Aug 18 - Fri, Oct 9
Multiple Airlines Logo
12:03 pm - 12:55 pm
PTY
-
DTW
23h 52m
1 stop
Multiple Airlines Logo
6:50 am - 4:06 pm
DTW
-
PTY
34h 16m
2 stops
$736Multiple Airlines
Wed, Aug 5 - Wed, Sep 16

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American Airlines flights from Panama City to Detroit Metropolitan Wayne County Airport

Our best American Airlines deals on Panama City to Detroit Metropolitan Wayne County Airport flight tickets
American Airlines
Nov 9
PTY2:43 pmPanama City Tocumen Intl
9h 06m
1 stop
DTW11:49 pmDetroit Metropolitan Wayne County
Nov 30
DTW9:24 pmDetroit Metropolitan Wayne County
16h 12m
2 stops
PTY1:36 pmPanama City Tocumen Intl
$878
American Airlines
Aug 5
PTY1:39 pmPanama City Tocumen Intl
24h 21m
2 stops
DTW3:00 pmDetroit Metropolitan Wayne County
Oct 9
DTW4:59 pmDetroit Metropolitan Wayne County
20h 53m
2 stops
PTY12:52 pmPanama City Tocumen Intl
$890
American Airlines
Aug 11
PTY1:39 pmPanama City Tocumen Intl
8h 20m
1 stop
DTW10:59 pmDetroit Metropolitan Wayne County
Sep 2
DTW6:00 amDetroit Metropolitan Wayne County
7h 39m
1 stop
PTY12:39 pmPanama City Tocumen Intl
$904

United Airlines flights from Panama City to Detroit Metropolitan Wayne County Airport

Our best United Airlines deals on Panama City to Detroit Metropolitan Wayne County Airport flight tickets
United Airlines
Nov 9
PTY8:55 amPanama City Tocumen Intl
35h 28m
3 stops
DTW8:23 pmDetroit Metropolitan Wayne County
Nov 30
DTW6:25 pmDetroit Metropolitan Wayne County
25h 37m
2 stops
PTY8:02 pmPanama City Tocumen Intl
$912
United Airlines
Aug 20
PTY3:30 pmPanama City Tocumen Intl
20h 54m
1 stop
DTW1:24 pmDetroit Metropolitan Wayne County
Aug 27
DTW7:02 pmDetroit Metropolitan Wayne County
10h 02m
1 stop
PTY4:04 amPanama City Tocumen Intl
$930
United Airlines
Sep 2
PTY9:45 amPanama City Tocumen Intl
12h 51m
1 stop
DTW11:36 pmDetroit Metropolitan Wayne County
Sep 5
DTW2:52 pmDetroit Metropolitan Wayne County
14h 12m
1 stop
PTY4:04 amPanama City Tocumen Intl
$1,035

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 8, 2026.
Use the filters below to find and compare flights from Panama City to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 8/21

5:30 am-1:04 am

3 stops18h 34m

Detroit Metropolitan Wayne County

Fri 8/28

6:00 am-12:35 am

3 stops19h 35m

$626

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 8/25

10:10 am-5:22 pm

2 stops30h 12m

Detroit Metropolitan Wayne County

Tue 10/6

11:00 am-8:19 pm

1 stop10h 19m

$635

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 8/25

3:50 pm-11:59 pm

2 stops31h 09m

Detroit Metropolitan Wayne County

Fri 9/25

5:30 pm-10:30 am

2 stops18h 00m

$669

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 8/18

3:50 pm-11:59 pm

2 stops31h 09m

Detroit Metropolitan Wayne County

Fri 10/9

5:30 pm-2:55 pm

3 stops22h 25m

$676

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 8/25

10:10 am-5:22 pm

2 stops30h 12m

Detroit Metropolitan Wayne County

Fri 9/25

11:00 am-8:19 pm

1 stop10h 19m

$681
Quickest round-trip

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 8/5

10:10 am-12:55 pm

2 stops25h 45m

Detroit Metropolitan Wayne County

Tue 10/13

11:00 am-8:19 pm

1 stop10h 19m

$687

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 8/21

10:10 am-5:22 pm

2 stops30h 12m

Detroit Metropolitan Wayne County

Fri 8/28

8:46 pm-8:31 pm

1 stop24h 45m

$703

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 8/25

12:03 pm-5:22 pm

1 stop28h 19m

Detroit Metropolitan Wayne County

Tue 10/6

11:00 am-8:19 pm

1 stop10h 19m

$718

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 8/18

10:00 am-1:04 am

1 stop14h 04m

Detroit Metropolitan Wayne County

Fri 10/9

3:38 pm-4:06 pm

2 stops25h 28m

$728

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 8/5

12:03 pm-12:55 pm

1 stop23h 52m

Detroit Metropolitan Wayne County

Wed 9/16

6:50 am-4:06 pm

2 stops34h 16m

$736

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
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When to book flights from Panama City to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Detroit Metropolitan Wayne County Airport (PTY to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Detroit Metropolitan Wayne County Airport

Fastest flight time

18h 34m

Direct flights

None
The fastest flight from Panama City to Detroit Metropolitan Wayne County Airport takes 18h 34m
There are no direct flights from Panama City to Detroit Metropolitan Wayne County Airport. There are no popular flight routes from Panama City to Detroit Metropolitan Wayne County Airport.
Search flight deals

Frequently asked questions about flying from Panama City to Detroit Metropolitan Wayne County Airport

  • How far is Panama City Tocumen Intl to Detroit Metropolitan Wayne County by plane?

    Detroit Metropolitan Wayne County is 2306.7 mi away from Panama City Tocumen Intl. By plane, this route typically takes 18h 34m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The travel and health documents required for your trip to Detroit Metropolitan Wayne County Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Detroit Metropolitan Wayne County Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Frequently asked questions about flying from Panama City to Detroit Metropolitan Wayne County Airport

  • How do I get Price Alerts for flights from Panama City to Detroit Metropolitan Wayne County Airport?

    Search flight deals from Panama City to Detroit Metropolitan Wayne County Airport. While viewing offers you’ll have the option to create a Price Alert.

  • How can I save money on flights from Panama City to Detroit Metropolitan Wayne County Airport with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    We aggregate our prices from over 700+ competitors from airlines to OTAs. We operate in over 30 markets worldwide to show you a wide range of travel options.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Romulus
Warren
Dearborn
Troy
Monroe
Southfield
Livonia
Novi
Port Clinton
Roseville
Port Huron
Sterling Heights
Dundee
Ypsilanti
Pontiac
Belleville
Brighton
Utica

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Detroit?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Detroit. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Detroit with flexible booking policies on momondo?

Flights from Panama City to Detroit with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Detroit?

Once all potential Panama City to Detroit flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Detroit right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Detroit from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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