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Cheap flights from Manchester, New Hampshire to Florence from $687

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Manchester, New Hampshire to Florence departing on 8/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Manchester, New Hampshire to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:15 am - 2:56 pm
MHT
-
FLO
6h 41m
2 stops
American Airlines Logo
3:22 pm - 9:56 pm
FLO
-
MHT
6h 34m
1 stop
$687American Airlines
Tue, Aug 18 - Mon, Aug 24
American Airlines Logo
6:00 am - 10:59 pm
MHT
-
FLO
16h 59m
2 stops
American Airlines Logo
6:22 am - 11:52 pm
FLO
-
MHT
17h 30m
2 stops
$780American Airlines
Tue, Aug 18 - Mon, Aug 24
American Airlines Logo
8:15 am - 2:56 pm
MHT
-
FLO
6h 41m
2 stops
American Airlines Logo
5:05 am - 9:36 am
FLO
-
MHT
4h 31m
1 stop
$781American Airlines
Thu, Aug 20 - Sun, Aug 23
American Airlines Logo
12:09 pm - 10:59 pm
MHT
-
FLO
10h 50m
2 stops
American Airlines Logo
5:05 am - 4:38 pm
FLO
-
MHT
11h 33m
2 stops
$802American Airlines
Thu, Aug 20 - Sun, Aug 23
American Airlines Logo
12:09 pm - 10:59 pm
MHT
-
FLO
10h 50m
2 stops
American Airlines Logo
5:05 am - 4:38 pm
FLO
-
MHT
11h 33m
2 stops
$807American Airlines
Fri, Aug 21 - Sun, Aug 23
American Airlines Logo
1:50 pm - 10:59 pm
MHT
-
FLO
9h 09m
1 stop
American Airlines Logo
3:22 pm - 1:00 pm
FLO
-
MHT
21h 38m
1 stop
$890American Airlines
Tue, Aug 18 - Mon, Aug 24
American Airlines Logo
7:05 am - 2:56 pm
MHT
-
FLO
7h 51m
1 stop
American Airlines Logo
5:05 am - 10:52 pm
FLO
-
MHT
17h 47m
1 stop
$989American Airlines
Thu, Aug 20 - Sun, Aug 23

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American Airlines flights from Manchester, New Hampshire to Florence, South Carolina

Our best American Airlines deals on Manchester, New Hampshire to Florence, South Carolina flight tickets
American Airlines
Aug 18
MHT8:15 amManchester
6h 41m
2 stops
FLO2:56 pmFlorence
Aug 24
FLO3:22 pmFlorence
6h 34m
1 stop
MHT9:56 pmManchester
$687
American Airlines
Aug 18
MHT6:00 amManchester
16h 59m
2 stops
FLO10:59 pmFlorence
Aug 24
FLO6:22 amFlorence
17h 30m
2 stops
MHT11:52 pmManchester
$780
American Airlines
Aug 20
MHT8:15 amManchester
6h 41m
2 stops
FLO2:56 pmFlorence
Aug 23
FLO5:05 amFlorence
4h 31m
1 stop
MHT9:36 amManchester
$781

momondo Fare Finder

 
Customize your flight search to find flights from Manchester, New Hampshire to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 21, 2026.
Use the filters below to find and compare flights from Manchester, New Hampshire to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ManchesterFlorence

MHT - FLO

MHTFLO

Manchester

Tue 8/18

8:15 am-2:56 pm

2 stops6h 41m

Florence

Mon 8/24

3:22 pm-9:56 pm

1 stop6h 34m

$687

ManchesterFlorence

MHT - FLO

MHTFLO

Manchester

Tue 8/18

6:00 am-10:59 pm

2 stops16h 59m

Florence

Mon 8/24

6:22 am-11:52 pm

2 stops17h 30m

$780
Quickest round-trip

ManchesterFlorence

MHT - FLO

MHTFLO

Manchester

Thu 8/20

8:15 am-2:56 pm

2 stops6h 41m

Florence

Sun 8/23

5:05 am-9:36 am

1 stop4h 31m

$781

ManchesterFlorence

MHT - FLO

MHTFLO

Manchester

Thu 8/20

12:09 pm-10:59 pm

2 stops10h 50m

Florence

Sun 8/23

5:05 am-4:38 pm

2 stops11h 33m

$802

ManchesterFlorence

MHT - FLO

MHTFLO

Manchester

Fri 8/21

12:09 pm-10:59 pm

2 stops10h 50m

Florence

Sun 8/23

5:05 am-4:38 pm

2 stops11h 33m

$807

ManchesterFlorence

MHT - FLO

MHTFLO

Manchester

Tue 8/18

1:50 pm-10:59 pm

1 stop9h 09m

Florence

Mon 8/24

3:22 pm-1:00 pm

1 stop21h 38m

$890

ManchesterFlorence

MHT - FLO

MHTFLO

Manchester

Thu 8/20

7:05 am-2:56 pm

1 stop7h 51m

Florence

Sun 8/23

5:05 am-10:52 pm

1 stop17h 47m

$989

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Manchester, New Hampshire to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, Delta and JetBlue are the top three most popular airlines that fly to Florence, South Carolina from Manchester, New Hampshire according to our data. American Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Manchester, New Hampshire to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Manchester, New Hampshire to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Manchester, New Hampshire to Florence, South Carolina (MHT to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Manchester, New Hampshire to Florence, South Carolina

Fastest flight time

6h 41m

Direct flights

None
The fastest flight from Manchester, New Hampshire to Florence, South Carolina takes 6h 41m
There are no direct flights from Manchester, New Hampshire to Florence, South Carolina. There are no popular flight routes from Manchester, New Hampshire to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Manchester, New Hampshire to Florence, South Carolina

  • How far is Manchester to Florence by plane?

    The distance between Manchester and Florence is about 754.2 mi. In terms of flight time, this usually takes a little over 6h 41m.

  • When did momondo last update prices for flights from Manchester Airport to Florence Airport?

    Prices for flights from Manchester Airport to Florence Airport refresh daily.

  • How old do you have to be to fly from Manchester Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Manchester Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Hartsville
Lake City
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Manchester to Florence?

Finding the right flight to Florence from Manchester is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Florence quick and easy, saving you time and money.

Can I find flights from Manchester to Florence with flexible booking policies on momondo?

Flights from Manchester to Florence with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Manchester to Florence?

Once you have performed a search for Manchester to Florence flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Manchester to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Manchester to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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