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Cheap flights from Knoxville to San Angelo from $448

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to San Angelo departing on 8/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Knoxville to San Angelo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:01 am - 12:35 pm
TYS
-
SJT
6h 34m
1 stop
American Airlines Logo
5:00 am - 12:56 pm
SJT
-
TYS
6h 56m
1 stop
$448American Airlines
Sat, Aug 1 - Tue, Aug 11
American Airlines Logo
5:00 am - 12:35 pm
TYS
-
SJT
8h 35m
2 stops
American Airlines Logo
5:00 am - 11:18 am
SJT
-
TYS
5h 18m
1 stop
$454American Airlines
Sat, Aug 1 - Tue, Aug 11
American Airlines Logo
5:24 am - 9:40 am
TYS
-
SJT
5h 16m
1 stop
American Airlines Logo
10:12 am - 5:19 pm
SJT
-
TYS
6h 07m
1 stop
$489American Airlines
Wed, Dec 9 - Thu, Dec 31
American Airlines Logo
5:24 am - 9:40 am
TYS
-
SJT
5h 16m
1 stop
American Airlines Logo
5:00 am - 2:21 pm
SJT
-
TYS
8h 21m
2 stops
$495American Airlines
Wed, Dec 9 - Thu, Dec 31
American Airlines Logo
4:22 pm - 11:55 pm
TYS
-
SJT
8h 33m
2 stops
American Airlines Logo
5:00 am - 3:57 pm
SJT
-
TYS
9h 57m
2 stops
$500American Airlines
Thu, Aug 13 - Tue, Aug 18
American Airlines Logo
6:40 am - 5:59 pm
TYS
-
SJT
12h 19m
2 stops
American Airlines Logo
5:00 am - 2:21 pm
SJT
-
TYS
8h 21m
2 stops
$535American Airlines
Wed, Dec 9 - Thu, Dec 31
American Airlines Logo
5:00 am - 12:35 pm
TYS
-
SJT
8h 35m
2 stops
American Airlines Logo
10:31 am - 10:58 pm
SJT
-
TYS
11h 27m
2 stops
$552American Airlines
Sat, Aug 1 - Tue, Aug 11
American Airlines Logo
5:35 pm - 10:24 pm
TYS
-
SJT
5h 49m
1 stop
American Airlines Logo
5:00 am - 1:06 pm
SJT
-
TYS
7h 06m
1 stop
$682American Airlines
Sat, Oct 3 - Sat, Oct 10
American Airlines Logo
2:00 pm - 10:24 pm
TYS
-
SJT
9h 24m
2 stops
American Airlines Logo
5:00 am - 1:06 pm
SJT
-
TYS
7h 06m
1 stop
$701American Airlines
Sat, Oct 3 - Sat, Oct 10
American Airlines Logo
2:00 pm - 10:24 pm
TYS
-
SJT
9h 24m
2 stops
American Airlines Logo
5:00 am - 3:53 pm
SJT
-
TYS
9h 53m
2 stops
$899American Airlines
Sat, Oct 3 - Sat, Oct 10

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American Airlines flights from Knoxville to San Angelo

Our best American Airlines deals on Knoxville to San Angelo flight tickets
American Airlines
Aug 1
TYS7:01 amKnoxville McGhee Tyson
6h 34m
1 stop
SJT12:35 pmSan Angelo Mathis Field
Aug 11
SJT5:00 amSan Angelo Mathis Field
6h 56m
1 stop
TYS12:56 pmKnoxville McGhee Tyson
$448
American Airlines
Aug 1
TYS5:00 amKnoxville McGhee Tyson
8h 35m
2 stops
SJT12:35 pmSan Angelo Mathis Field
Aug 11
SJT5:00 amSan Angelo Mathis Field
5h 18m
1 stop
TYS11:18 amKnoxville McGhee Tyson
$454
American Airlines
Dec 9
TYS5:24 amKnoxville McGhee Tyson
5h 16m
1 stop
SJT9:40 amSan Angelo Mathis Field
Dec 31
SJT10:12 amSan Angelo Mathis Field
6h 07m
1 stop
TYS5:19 pmKnoxville McGhee Tyson
$489

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to San Angelo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 25, 2026.
Use the filters below to find and compare flights from Knoxville to San Angelo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Sat 8/1

7:01 am-12:35 pm

1 stop6h 34m

San Angelo Mathis Field

Tue 8/11

5:00 am-12:56 pm

1 stop6h 56m

$448

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Sat 8/1

5:00 am-12:35 pm

2 stops8h 35m

San Angelo Mathis Field

Tue 8/11

5:00 am-11:18 am

1 stop5h 18m

$454
Quickest round-trip

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Wed 12/9

5:24 am-9:40 am

1 stop5h 16m

San Angelo Mathis Field

Thu 12/31

10:12 am-5:19 pm

1 stop6h 07m

$489

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Wed 12/9

5:24 am-9:40 am

1 stop5h 16m

San Angelo Mathis Field

Thu 12/31

5:00 am-2:21 pm

2 stops8h 21m

$495

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Thu 8/13

4:22 pm-11:55 pm

2 stops8h 33m

San Angelo Mathis Field

Tue 8/18

5:00 am-3:57 pm

2 stops9h 57m

$500

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Wed 12/9

6:40 am-5:59 pm

2 stops12h 19m

San Angelo Mathis Field

Thu 12/31

5:00 am-2:21 pm

2 stops8h 21m

$535

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Sat 8/1

5:00 am-12:35 pm

2 stops8h 35m

San Angelo Mathis Field

Tue 8/11

10:31 am-10:58 pm

2 stops11h 27m

$552

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Sat 10/3

5:35 pm-10:24 pm

1 stop5h 49m

San Angelo Mathis Field

Sat 10/10

5:00 am-1:06 pm

1 stop7h 06m

$682

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Sat 10/3

2:00 pm-10:24 pm

2 stops9h 24m

San Angelo Mathis Field

Sat 10/10

5:00 am-1:06 pm

1 stop7h 06m

$701

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Sat 10/3

2:00 pm-10:24 pm

2 stops9h 24m

San Angelo Mathis Field

Sat 10/10

5:00 am-3:53 pm

2 stops9h 53m

$899

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Knoxville to San Angelo

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to San Angelo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to San Angelo (TYS to SJT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to San Angelo

Fastest flight time

5h 16m

Direct flights

None
The fastest flight from Knoxville to San Angelo takes 5h 16m
There are no direct flights from Knoxville to San Angelo. There are no popular flight routes from Knoxville to San Angelo.
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Frequently asked questions about flying from Knoxville to San Angelo

  • How far is Knoxville McGhee Tyson to San Angelo Mathis Field by plane?

    The distance between Knoxville McGhee Tyson and San Angelo Mathis Field is about 996.6 mi. Typically, this will take 5h 16m by plane in normal conditions.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to San Angelo Mathis Field Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to San Angelo Mathis Field Airport are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to San Angelo Mathis Field Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to San Angelo Mathis Field Airport.

  • What documentation or ID do you need to fly to San Angelo Mathis Field Airport?

    The required travel and health documents for your San Angelo Mathis Field Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Angelo Mathis Field Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Frequently asked questions about flying from Knoxville to San Angelo

  • How do I get Price Alerts for flights from Knoxville to San Angelo?

    Price Alerts will notify you by email when the price for flights to San Angelo from Knoxville decreases. To activate this, select your desired travel dates and search for offers. While browsing through offers you’ll see the Price Alert widget toggle. Click it to turn on notifications.

  • How can I save money on flights from Knoxville to San Angelo with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Traveling to a place near San Angelo?

Book flights to San Angelo if you plan to visit one of these locations
Sonora

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to San Angelo?

Finding the right flight to San Angelo from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Angelo quick and easy, saving you time and money.

Can I find flights from Knoxville to San Angelo with flexible booking policies on momondo?

Yes. All flights to San Angelo from Knoxville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Knoxville to San Angelo?

Once all potential Knoxville to San Angelo flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to San Angelo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to San Angelo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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