Cheap flights from Knoxville to San Angelo from $796

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to San Angelo departing on 11/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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American Airlines Logo
4:27 pm - 10:23 pmTYS-SJT
6h 56m1 stop
American Airlines Logo
6:47 pm - 12:08 amSJT-TYS
4h 21m1 stop
$796American Airlines
Find Deal
Tue, Nov 11 - Fri, Nov 14
American Airlines Logo
10:16 am - 10:23 pmTYS-SJT
13h 07m2 stops
American Airlines Logo
6:47 pm - 12:08 amSJT-TYS
4h 21m1 stop
$802American Airlines
Find Deal
Tue, Nov 11 - Fri, Nov 14
American Airlines Logo
12:46 pm - 10:23 pmTYS-SJT
10h 37m2 stops
American Airlines Logo
10:23 am - 9:17 pmSJT-TYS
9h 54m2 stops
$920American Airlines
Find Deal
Tue, Nov 11 - Fri, Nov 14

American Airlines flights from Knoxville to San Angelo

Our best American Airlines deals on Knoxville to San Angelo flight tickets
American Airlines
Nov 11
TYS4:27 pmKnoxville McGhee Tyson
6h 56m
1 stop
SJT10:23 pmSan Angelo Mathis Field
Nov 14
SJT6:47 pmSan Angelo Mathis Field
4h 21m
1 stop
TYS12:08 amKnoxville McGhee Tyson
American Airlines
Nov 11
TYS10:16 amKnoxville McGhee Tyson
13h 07m
2 stops
SJT10:23 pmSan Angelo Mathis Field
Nov 14
SJT6:47 pmSan Angelo Mathis Field
4h 21m
1 stop
TYS12:08 amKnoxville McGhee Tyson
American Airlines
Nov 11
TYS12:46 pmKnoxville McGhee Tyson
10h 37m
2 stops
SJT10:23 pmSan Angelo Mathis Field
Nov 14
SJT10:23 amSan Angelo Mathis Field
9h 54m
2 stops
TYS9:17 pmKnoxville McGhee Tyson

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to San Angelo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Knoxville to San Angelo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Tue 11/11

4:27 pm-10:23 pm

1 stop6h 56m

San Angelo Mathis Field

Fri 11/14

6:47 pm-12:08 am

1 stop4h 21m

$796

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Tue 11/11

10:16 am-10:23 pm

2 stops13h 07m

San Angelo Mathis Field

Fri 11/14

6:47 pm-12:08 am

1 stop4h 21m

$802

KnoxvilleSan Angelo

TYS - SJT

TYSSJT

Knoxville McGhee Tyson

Tue 11/11

12:46 pm-10:23 pm

2 stops10h 37m

San Angelo Mathis Field

Fri 11/14

10:23 am-9:17 pm

2 stops9h 54m

$920

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Knoxville to San Angelo

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to San Angelo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to San Angelo (TYS to SJT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to San Angelo

Direct flights

None
There are no direct flights from Knoxville to San Angelo. There are no popular flight routes from Knoxville to San Angelo.
  • How far is Knoxville McGhee Tyson to San Angelo Mathis Field by plane?

    The distance between Knoxville McGhee Tyson and San Angelo Mathis Field is about 996.6 mi. Typically, this will take 6h 56m by plane in normal conditions.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to San Angelo Mathis Field Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to San Angelo Mathis Field Airport are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to San Angelo Mathis Field Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to San Angelo Mathis Field Airport.

  • What documentation or ID do you need to fly to San Angelo Mathis Field Airport?

    The required travel and health documents for your San Angelo Mathis Field Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Angelo Mathis Field Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • How do I get Price Alerts for flights from Knoxville to San Angelo?

    Price Alerts will notify you by email when the price for flights to San Angelo from Knoxville decreases. To activate this, select your desired travel dates and search for offers. While browsing through offers you’ll see the Price Alert widget toggle. Click it to turn on notifications.

  • How can I save money on flights from Knoxville to San Angelo with momondo?

    By using tools like our “Price Calendar”, you can see the best day to fly round-trip for your travels. Our “Price Forecast” tool uses AI to predict whether you should purchase or hold off on booking for potentially cheaper prices. Explore shows you all flight options from a city or airport to build your own unique adventure. The Discover blog also provides valuable insights for saving money while booking your experience. After searching you can toggle on “Price Alerts” to track prices for your desired flight and book at the ideal moment.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Traveling to a place near San Angelo?

Book flights to San Angelo if you plan to visit one of these locations
Sonora

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to San Angelo?

Finding the right flight to San Angelo from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Angelo quick and easy, saving you time and money.

Can I find flights from Knoxville to San Angelo with flexible booking policies on momondo?

Yes. All flights to San Angelo from Knoxville on momondo can be compared and filtered by various policies on offer, including flexible booking.

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1 adult
Sat 11/29
Sat 12/6

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