Cheap flights from Knoxville to Minneapolis from $80

The month of June is, on average, the cheapest month to fly to Minneapolis from Knoxville, with most prices found around $171. If you aren’t able to travel during the month of June, then book flights to Minneapolis from Knoxville during May instead. Flights to Minneapolis in May, while not as cheap as those in June, still average around $299.

The cheapest day to depart from Knoxville to Minneapolis is on a Friday when prices can be found for as low as $371. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Minneapolis on Sunday is $553.

Our most recent data shows that the best time of day to fly to Minneapolis is in the afternoon. Flights from Knoxville to Minneapolis during this time can be as low as $407. Try not to purchase tickets in the morning because they tend to be around $471. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Knoxville McGhee Tyson to Minneapolis St Paul for the best Knoxville McGhee Tyson - Minneapolis St Paul flight prices

You are more likely to see cheaper flights to Minneapolis from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to Minneapolis for around $413 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Minneapolis from Knoxville for as low as $247 on momondo.

There are 4 cabin classes available to choose from on Knoxville McGhee Tyson to Minneapolis St Paul flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 48% on your flight if you consider stops on a Knoxville to Minneapolis flight.

Delta is the most popular carrier operating from Knoxville McGhee Tyson to Minneapolis St Paul

Delta, American Airlines and Allegiant Air are the top three most popular airlines that fly to Minneapolis from Knoxville according to our data. Delta is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Minneapolis. Keep in mind that there are 5 different airlines that fly to Minneapolis on a routine basis, so you have a few additional options to choose from.

Chicago (ORD) was the most common stop: 80% of momondo users choosing 1-stop flights on this route connected there.

Flights via Denver (DEN) offer the lowest average round-trip price of $218.

Flights connecting via Chicago (ORD) have the shortest average one-way travel time: 5h 07m.

Chicago (ORD) has the shortest average layover time for this route: 1h 59m.

The number of flights available between Knoxville and Minneapolis is 2 per day as of March 2026. The most frequent departure time is 6:00AM, with 100% of daily flights leaving at noon.

14 flights are operational weekly from Knoxville to Minneapolis as of March 2026. The most popular departure day for this route is Mon, with 14% of flights per week taking off on this day.