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Cheap flights from Knoxville to New Orleans from $112

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to New Orleans departing on 3/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to New Orleans

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:00 pm - 10:44 pm
TYS
-
MSY
8h 44m
1 stop
Multiple Airlines Logo
6:00 am - 2:06 pm
MSY
-
TYS
7h 06m
1 stop
$192Multiple Airlines
Tue, Mar 31 - Tue, Apr 7
Multiple Airlines Logo
3:00 pm - 8:19 am
TYS
-
MSY
18h 19m
1 stop
Multiple Airlines Logo
6:00 am - 10:40 am
MSY
-
TYS
27h 40m
1 stop
$214Multiple Airlines
Tue, Mar 17 - Tue, Mar 24
Multiple Airlines Logo
3:00 pm - 8:19 am
TYS
-
MSY
18h 19m
1 stop
Multiple Airlines Logo
3:30 pm - 10:36 am
MSY
-
TYS
18h 06m
2 stops
$224Multiple Airlines
Tue, Mar 31 - Tue, Apr 7
Multiple Airlines Logo
11:00 am - 6:55 pm
TYS
-
MSY
8h 55m
1 stop
Multiple Airlines Logo
6:00 am - 2:10 pm
MSY
-
TYS
7h 10m
1 stop
$232Multiple Airlines
Sat, Mar 28 - Tue, Mar 31
Multiple Airlines Logo
3:00 pm - 10:44 pm
TYS
-
MSY
8h 44m
1 stop
Multiple Airlines Logo
3:30 pm - 10:40 am
MSY
-
TYS
18h 10m
2 stops
$235Multiple Airlines
Tue, Mar 17 - Tue, Mar 24
Multiple Airlines Logo
7:20 am - 7:01 pm
TYS
-
MSY
12h 41m
1 stop
Multiple Airlines Logo
6:00 am - 8:51 pm
MSY
-
TYS
13h 51m
1 stop
$236Multiple Airlines
Sat, Mar 21 - Sat, Mar 28
Multiple Airlines Logo
7:20 am - 7:01 pm
TYS
-
MSY
12h 41m
1 stop
Multiple Airlines Logo
6:00 am - 8:51 pm
MSY
-
TYS
13h 51m
1 stop
$239Multiple Airlines
Sat, Mar 21 - Sat, Mar 28
Multiple Airlines Logo
8:00 am - 6:55 pm
TYS
-
MSY
11h 55m
1 stop
Multiple Airlines Logo
7:10 pm - 2:10 pm
MSY
-
TYS
18h 00m
1 stop
$241Multiple Airlines
Sat, Mar 28 - Mon, Mar 30
Multiple Airlines Logo
5:10 pm - 10:44 pm
TYS
-
MSY
6h 34m
1 stop
Multiple Airlines Logo
4:38 pm - 2:58 pm
MSY
-
TYS
21h 20m
1 stop
$242Multiple Airlines
Thu, Apr 9 - Mon, Apr 13
Multiple Airlines Logo
7:20 am - 7:01 pm
TYS
-
MSY
12h 41m
1 stop
Multiple Airlines Logo
6:00 am - 8:51 pm
MSY
-
TYS
13h 51m
1 stop
$243Multiple Airlines
Sat, Mar 21 - Sat, Mar 28

American Airlines flights from Knoxville to New Orleans

Our best American Airlines deals on Knoxville to New Orleans flight tickets
American Airlines
May 11
TYS3:58 pmKnoxville McGhee Tyson
6h 21m
1 stop
MSY9:19 pmNew Orleans Louis Armstrong
May 13
MSY5:30 amNew Orleans Louis Armstrong
6h 00m
1 stop
TYS12:30 pmKnoxville McGhee Tyson
$265
American Airlines
May 9
TYS3:58 pmKnoxville McGhee Tyson
6h 12m
1 stop
MSY9:10 pmNew Orleans Louis Armstrong
May 12
MSY6:34 amNew Orleans Louis Armstrong
7h 45m
1 stop
TYS3:19 pmKnoxville McGhee Tyson
$277
American Airlines
May 6
TYS5:00 amKnoxville McGhee Tyson
4h 30m
1 stop
MSY8:30 amNew Orleans Louis Armstrong
May 10
MSY5:30 amNew Orleans Louis Armstrong
6h 00m
1 stop
TYS12:30 pmKnoxville McGhee Tyson
$308

Southwest flights from Knoxville to New Orleans

Our best Southwest deals on Knoxville to New Orleans flight tickets
Southwest
Mar 31
TYS6:35 amKnoxville McGhee Tyson
9h 40m
2 stops
MSY3:15 pmNew Orleans Louis Armstrong
Apr 7
MSY6:45 amNew Orleans Louis Armstrong
6h 35m
2 stops
TYS2:20 pmKnoxville McGhee Tyson
$287
Southwest
Apr 11
TYS1:55 pmKnoxville McGhee Tyson
4h 45m
1 stop
MSY5:40 pmNew Orleans Louis Armstrong
Apr 18
MSY6:30 amNew Orleans Louis Armstrong
4h 10m
1 stop
TYS11:40 amKnoxville McGhee Tyson
$289
Southwest
Apr 11
TYS1:55 pmKnoxville McGhee Tyson
4h 45m
1 stop
MSY5:40 pmNew Orleans Louis Armstrong
Apr 18
MSY8:30 amNew Orleans Louis Armstrong
9h 00m
2 stops
TYS6:30 pmKnoxville McGhee Tyson
$294

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to New Orleans that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Knoxville to New Orleans that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Tue 3/31

3:00 pm-10:44 pm

1 stop8h 44m

New Orleans Louis Armstrong

Tue 4/7

6:00 am-2:06 pm

1 stop7h 06m

$192

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Tue 3/17

3:00 pm-8:19 am

1 stop18h 19m

New Orleans Louis Armstrong

Tue 3/24

6:00 am-10:40 am

1 stop27h 40m

$214

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Tue 3/31

3:00 pm-8:19 am

1 stop18h 19m

New Orleans Louis Armstrong

Tue 4/7

3:30 pm-10:36 am

2 stops18h 06m

$224

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 3/28

11:00 am-6:55 pm

1 stop8h 55m

New Orleans Louis Armstrong

Tue 3/31

6:00 am-2:10 pm

1 stop7h 10m

$232

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Tue 3/17

3:00 pm-10:44 pm

1 stop8h 44m

New Orleans Louis Armstrong

Tue 3/24

3:30 pm-10:40 am

2 stops18h 10m

$235

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 3/21

7:20 am-7:01 pm

1 stop12h 41m

New Orleans Louis Armstrong

Sat 3/28

6:00 am-8:51 pm

1 stop13h 51m

$236

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 3/21

7:20 am-7:01 pm

1 stop12h 41m

New Orleans Louis Armstrong

Sat 3/28

6:00 am-8:51 pm

1 stop13h 51m

$239

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 3/28

8:00 am-6:55 pm

1 stop11h 55m

New Orleans Louis Armstrong

Mon 3/30

7:10 pm-2:10 pm

1 stop18h 00m

$241

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Thu 4/9

5:10 pm-10:44 pm

1 stop6h 34m

New Orleans Louis Armstrong

Mon 4/13

4:38 pm-2:58 pm

1 stop21h 20m

$242

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 3/21

7:20 am-7:01 pm

1 stop12h 41m

New Orleans Louis Armstrong

Sat 3/28

6:00 am-8:51 pm

1 stop13h 51m

$243

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to New Orleans from

How to get the cheapest flight ticket from Knoxville to New Orleans

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to New Orleans?

The cheapest month to fly to New Orleans from Knoxville is in August. Flight prices, which tend to average around $293, are often lower during this time because this is during the off-season. If you are unable to visit New Orleans during the month of August, then departing from Knoxville during the month November is also very affordable. Most momondo users find prices during this month for around $328.

How far in advance should I book a flight to New Orleans?

You are more likely to see cheaper flights to New Orleans from Knoxville when booking weeks ahead of your departure date. In general, you can expect to find flights to New Orleans for around $380 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to New Orleans from Knoxville for as low as $262 on momondo.

How have Knoxville to New Orleans flight prices changed over time?

When to book flights from Knoxville to New Orleans

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to New Orleans according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to New Orleans (TYS to MSY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to New Orleans

Fastest flight time

3h 30m

Direct flights

None
The fastest flight from Knoxville to New Orleans takes 3h 30m
There are no direct flights from Knoxville to New Orleans. There are no popular flight routes from Knoxville to New Orleans.
Search flight deals

  • How far is Knoxville McGhee Tyson to New Orleans Louis Armstrong by plane?

    Knoxville McGhee Tyson and New Orleans Louis Armstrong are 546.5 mi apart from one another. Typically, this will take 3h 30m by plane in normal conditions.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to New Orleans Louis Armstrong Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to New Orleans Louis Armstrong Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to New Orleans Louis Armstrong Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to New Orleans Louis Armstrong Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to New Orleans Louis Armstrong Airport.

  • What documentation or ID do you need to fly to New Orleans Louis Armstrong Airport?

    The required travel and health documents for your New Orleans Louis Armstrong Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at New Orleans Louis Armstrong Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to New Orleans?

Best airlines flying from Knoxville to New Orleans

Compare and see reviews for airlines that fly from Knoxville to New Orleans with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $228Free CancellationRating
7.1
11,375 reviews
Search American Airlines flights
DeltaPriceFrom $248Free CancellationRating
7.9
8,242 reviews
Search Delta flights
United AirlinesPriceFrom $270Free CancellationRating
7.4
9,377 reviews
Search United Airlines flights
SouthwestPriceFrom $286Free CancellationRating
8.0
4,302 reviews
Search Southwest flights

Traveling to a place near New Orleans?

Book flights to New Orleans if you plan to visit one of these locations
Metairie
Hammond
Slidell
Kenner
Houma
Gonzales
Gretna
Covington
Thibodaux
Lockport
Springfield

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to New Orleans?

Finding the right flight to New Orleans from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to New Orleans quick and easy, saving you time and money.

Can I find flights from Knoxville to New Orleans with flexible booking policies on momondo?

Flights from Knoxville to New Orleans with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Knoxville to New Orleans?

Once you have performed a search for Knoxville to New Orleans flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to New Orleans right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to New Orleans from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your New Orleans trip

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