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Cheap flights from Knoxville to Greenville from $279

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Greenville departing on 12/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:45 am - 6:22 pmTYS-PGV
6h 37m1 stop
American Airlines Logo
1:00 pm - 4:53 pmPGV-TYS
3h 53m1 stop
$387American Airlines
Find Deal
Fri, Oct 31 - Tue, Nov 4
American Airlines Logo
8:15 am - 12:01 pmTYS-PGV
3h 46m1 stop
American Airlines Logo
6:00 am - 4:37 pmPGV-TYS
10h 37m2 stops
$392American Airlines
Find Deal
Fri, Oct 31 - Tue, Nov 4
American Airlines Logo
8:21 pm - 11:40 pmTYS-PGV
3h 19m1 stop
American Airlines Logo
3:55 pm - 7:17 pmPGV-TYS
3h 22m1 stop
$431American Airlines
Find Deal
Sat, Mar 7 - Tue, Mar 10
American Airlines Logo
4:41 pm - 10:34 amTYS-PGV
17h 53m2 stops
American Airlines Logo
5:00 am - 10:14 amPGV-TYS
5h 14m1 stop
$446American Airlines
Find Deal
Fri, Oct 31 - Sun, Nov 2
American Airlines Logo
10:43 am - 11:10 pmTYS-PGV
12h 27m2 stops
American Airlines Logo
5:56 pm - 10:54 pmPGV-TYS
4h 58m1 stop
$451American Airlines
Find Deal
Wed, Oct 29 - Sun, Nov 2
American Airlines Logo
12:46 pm - 6:51 pmTYS-PGV
6h 05m1 stop
American Airlines Logo
5:56 pm - 10:54 pmPGV-TYS
4h 58m1 stop
$497American Airlines
Find Deal
Tue, Nov 18 - Thu, Nov 20
American Airlines Logo
8:21 pm - 11:40 pmTYS-PGV
3h 19m1 stop
American Airlines Logo
11:00 am - 10:10 pmPGV-TYS
11h 10m2 stops
$500American Airlines
Find Deal
Sat, Mar 7 - Tue, Mar 10
American Airlines Logo
6:06 am - 6:51 pmTYS-PGV
12h 45m2 stops
American Airlines Logo
5:03 am - 10:19 amPGV-TYS
5h 16m1 stop
$522American Airlines
Find Deal
Tue, Nov 18 - Thu, Nov 20
American Airlines Logo
4:41 pm - 10:34 amTYS-PGV
17h 53m2 stops
American Airlines Logo
5:00 am - 3:48 pmPGV-TYS
10h 48m2 stops
$578American Airlines
Find Deal
Fri, Oct 31 - Sun, Nov 2
American Airlines Logo
6:06 am - 6:51 pmTYS-PGV
12h 45m2 stops
American Airlines Logo
10:56 am - 9:33 pmPGV-TYS
10h 37m2 stops
$631American Airlines
Find Deal
Tue, Nov 18 - Thu, Nov 20

American Airlines flights from Knoxville to Greenville, North Carolina

Our best American Airlines deals on Knoxville to Greenville, North Carolina flight tickets
American Airlines
Oct 31
TYS11:45 amKnoxville McGhee Tyson
6h 37m
1 stop
PGV6:22 pmPitt-Greenville
Nov 4
PGV1:00 pmPitt-Greenville
3h 53m
1 stop
TYS4:53 pmKnoxville McGhee Tyson
$387
Find similar
American Airlines
Oct 31
TYS8:15 amKnoxville McGhee Tyson
3h 46m
1 stop
PGV12:01 pmPitt-Greenville
Nov 4
PGV6:00 amPitt-Greenville
10h 37m
2 stops
TYS4:37 pmKnoxville McGhee Tyson
$392
Find similar
American Airlines
Mar 7
TYS8:21 pmKnoxville McGhee Tyson
3h 19m
1 stop
PGV11:40 pmPitt-Greenville
Mar 10
PGV3:55 pmPitt-Greenville
3h 22m
1 stop
TYS7:17 pmKnoxville McGhee Tyson
$431
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Greenville, North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Knoxville to Greenville, North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Fri 10/31

11:45 am-6:22 pm

1 stop6h 37m

Pitt-Greenville

Tue 11/4

1:00 pm-4:53 pm

1 stop3h 53m

$387

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Fri 10/31

8:15 am-12:01 pm

1 stop3h 46m

Pitt-Greenville

Tue 11/4

6:00 am-4:37 pm

2 stops10h 37m

$392

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Sat 3/7

8:21 pm-11:40 pm

1 stop3h 19m

Pitt-Greenville

Tue 3/10

3:55 pm-7:17 pm

1 stop3h 22m

$431

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Fri 10/31

4:41 pm-10:34 am

2 stops17h 53m

Pitt-Greenville

Sun 11/2

5:00 am-10:14 am

1 stop5h 14m

$446

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Wed 10/29

10:43 am-11:10 pm

2 stops12h 27m

Pitt-Greenville

Sun 11/2

5:56 pm-10:54 pm

1 stop4h 58m

$451

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Tue 11/18

12:46 pm-6:51 pm

1 stop6h 05m

Pitt-Greenville

Thu 11/20

5:56 pm-10:54 pm

1 stop4h 58m

$497

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Sat 3/7

8:21 pm-11:40 pm

1 stop3h 19m

Pitt-Greenville

Tue 3/10

11:00 am-10:10 pm

2 stops11h 10m

$500

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Tue 11/18

6:06 am-6:51 pm

2 stops12h 45m

Pitt-Greenville

Thu 11/20

5:03 am-10:19 am

1 stop5h 16m

$522

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Fri 10/31

4:41 pm-10:34 am

2 stops17h 53m

Pitt-Greenville

Sun 11/2

5:00 am-3:48 pm

2 stops10h 48m

$578

KnoxvilleGreenville

TYS - PGV

TYSPGV

Knoxville McGhee Tyson

Tue 11/18

6:06 am-6:51 pm

2 stops12h 45m

Pitt-Greenville

Thu 11/20

10:56 am-9:33 pm

2 stops10h 37m

$631

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Knoxville to Greenville, North Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Knoxville McGhee Tyson to Pitt-Greenville?

American Airlines is the most popular carrier operating from Knoxville McGhee Tyson to Pitt-Greenville

What airlines fly to Greenville, North Carolina?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Greenville, North Carolina from Knoxville according to our data. American Airlines is the first choice among our users, with 81% of people opting to fly with this airline when traveling to Greenville, North Carolina. Keep in mind that there are 3 different airlines that fly to Greenville, North Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Knoxville to Greenville, North Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Greenville, North Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Greenville, North Carolina (TYS to PGV) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Greenville, North Carolina

Direct flights

None
There are no direct flights from Knoxville to Greenville, North Carolina. There are no popular flight routes from Knoxville to Greenville, North Carolina.
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  • How far is Knoxville McGhee Tyson to Pitt-Greenville by plane?

    The distance between Knoxville McGhee Tyson and Pitt-Greenville is about 367.8 mi. In terms of flight time, this usually takes a little over 3h 19m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Pitt-Greenville Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Pitt-Greenville Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Pitt-Greenville Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Pitt-Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Pitt-Greenville Airport.

  • What documentation or ID do you need to fly to Pitt-Greenville Airport?

    The necessary travel and health documents for your Pitt-Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Greenville, North Carolina?

Best airlines flying from Knoxville to Greenville, North Carolina

Compare and see reviews for airlines that fly from Knoxville to Greenville, North Carolina with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $218Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Washington
Kinston
Williamston
Plymouth

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Greenville?

It is quick and easy to find Knoxville to Greenville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Greenville that suits you.

Can I find flights from Knoxville to Greenville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Greenville from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Greenville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Greenville from Knoxville.

I’m not ready to book a flight from Knoxville to Greenville right now. Can momondo alert me if prices change?

Price alerts on flights to Greenville from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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