What is the cheapest airline that flies from Knoxville McGhee Tyson to Detroit?

Southwest is the most popular carrier operating from Knoxville McGhee Tyson to Detroit

How many flights depart from Knoxville to Detroit on average per week?

As of September 2026, there are 74 flights per week flying from Knoxville to Detroit. The most common day of the week flights depart is Mon, with 16% of flights taking off on this day.

How many flights depart from Knoxville to Detroit on average per day?

The number of flights available between Knoxville and Detroit is 10 per day as of September 2026. The most frequent departure time is 7:00AM, with 68% of daily flights leaving at noon.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Detroit?

Prices for flights from Knoxville McGhee Tyson Airport to Detroit were last updated today.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Detroit?

The number of operators available for flights from Knoxville McGhee Tyson Airport to Detroit is 1 as of September 2026.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Detroit?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Detroit.

What documentation or ID do you need to fly to Detroit?

The necessary travel and health documents for your Detroit trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$76 Cheap Flights from Knoxville to Detroit in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Detroit

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Cheap round-trip flights

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7:45 am - 8:04 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

12h 19m1 stop Washington, D.C. Dulles Intl

4:29 pm - 5:14 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

24h 45m1 stop Fort Lauderdale

$203Multiple Airlines

Thu, Oct 22 - Mon, Oct 26

7:45 am - 8:04 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

12h 19m1 stop Washington, D.C. Dulles Intl

8:25 pm - 10:05 amDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

37h 40m2 stops Tampa Fort Lauderdale

$245Multiple Airlines

Thu, Oct 22 - Mon, Oct 26

9:00 pm - 11:11 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

14h 11m1 stop Fort Lauderdale

9:33 pm - 8:27 amDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

10h 54m1 stop Fort Lauderdale

$249Multiple Airlines

Thu, Dec 3 - Sun, Dec 6

9:05 am - 11:29 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

14h 24m1 stop Fort Lauderdale

11:37 am - 9:44 amDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

22h 07m2 stops Tampa Washington, D.C. Dulles Intl

$264Multiple Airlines

Thu, Oct 22 - Sat, Oct 24

7:45 am - 12:39 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

40h 54m2 stops Washington, D.C. Dulles Intl Atlanta Hartsfield-Jackson

9:07 pm - 12:14 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

15h 07m1 stop Orlando

$274Multiple Airlines

Thu, Oct 22 - Thu, Oct 29

7:00 am - 12:43 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

17h 43m1 stop Tampa St. Petersburg

6:12 pm - 11:26 amDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

17h 14m1 stop Tampa

$279Multiple Airlines

Thu, Feb 25 - Sun, Feb 28

7:45 am - 12:06 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

28h 21m2 stops Washington, D.C. Dulles Intl Atlanta Hartsfield-Jackson

4:29 pm - 5:14 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

24h 45m1 stop Fort Lauderdale

$295Multiple Airlines

Thu, Oct 29 - Mon, Nov 2

1:57 pm - 10:35 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

20h 38m2 stops Philadelphia Atlanta Hartsfield-Jackson

7:55 pm - 12:10 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

16h 15m1 stop Fort Lauderdale

$302Multiple Airlines

Fri, Jan 8 - Mon, Jan 11

5:10 pm - 6:52 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 42mnonstop

4:43 pm - 6:22 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 39mnonstop

$367Delta

Thu, Dec 3 - Sun, Dec 6

11:45 am - 1:29 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 44mnonstop

4:44 pm - 6:24 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 40mnonstop

$367Delta

Fri, Oct 16 - Mon, Oct 19

Cheap last minute flights

Enter your travel dates to find the best prices.

7:50 am - 12:30 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

4h 40m1 stop Baltimore/Washington

2:45 pm - 7:55 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

5h 10m1 stop Baltimore/Washington

$507Southwest

Sat, Sep 26 - Tue, Sep 29

7:50 am - 12:30 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

4h 40m1 stop Baltimore/Washington

12:55 pm - 7:00 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

6h 05m2 stops Chicago Midway Nashville Intl

$512Southwest

Sat, Sep 26 - Tue, Sep 29

7:15 am - 1:15 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

6h 00m1 stop Nashville Intl

7:05 am - 5:20 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

10h 15m2 stops Lambert-St Louis Dallas Love Field

$518Southwest

Thu, Oct 1 - Sun, Oct 4

1:37 pm - 8:02 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

6h 25m1 stop Washington, D.C. Dulles Intl

4:23 pm - 10:35 amDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

18h 12m1 stop Fort Lauderdale

$521Multiple Airlines

Thu, Oct 1 - Sun, Oct 4

6:50 am - 9:05 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

14h 15m2 stops Nashville Intl Baltimore/Washington

6:25 am - 2:20 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

7h 55m2 stops Lambert-St Louis Dallas Love Field

$523Southwest

Sat, Sep 26 - Tue, Sep 29

10:28 am - 11:35 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

25h 07m1 stop Orlando

8:57 pm - 1:02 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

40h 05m2 stops Orlando Newark

$578Multiple Airlines

Wed, Sep 30 - Thu, Oct 1

10:28 am - 11:35 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

25h 07m1 stop Orlando

4:23 pm - 8:15 amDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

15h 52m1 stop Fort Lauderdale

$583Multiple Airlines

Wed, Sep 30 - Thu, Oct 1

11:08 am - 4:38 pmTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

5h 30m1 stop Washington, D.C. Reagan-National

11:11 am - 5:35 pmDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

6h 24m1 stop Philadelphia

$624American Airlines

Thu, Oct 1 - Thu, Oct 8

7:33 am - 9:15 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 42mnonstop

8:35 am - 10:18 amDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 43mnonstop

$625Delta

Thu, Oct 1 - Sun, Oct 4

7:33 am - 9:15 amTYS Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County

1h 42mnonstop

8:35 am - 10:18 amDTW Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson

1h 43mnonstop

$627Delta

Thu, Oct 1 - Mon, Oct 5

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American Airlines flights from Knoxville to Detroit

Our best American Airlines deals on Knoxville to Detroit flight tickets

American Airlines

Nov 24

TYS8:50 amKnoxville McGhee Tyson

4h 05m

1 stop

DTW12:55 pmDetroit Metropolitan Wayne County

Nov 27

DTW10:15 amDetroit Metropolitan Wayne County

7h 20m

1 stop

TYS5:35 pmKnoxville McGhee Tyson

$379

American Airlines

Oct 16

TYS4:49 pmKnoxville McGhee Tyson

5h 52m

1 stop

DTW10:41 pmDetroit Metropolitan Wayne County

Oct 19

DTW1:35 pmDetroit Metropolitan Wayne County

4h 45m

1 stop

TYS6:20 pmKnoxville McGhee Tyson

$385

American Airlines

Oct 3

TYS5:35 pmKnoxville McGhee Tyson

6h 08m

1 stop

DTW11:43 pmDetroit Metropolitan Wayne County

Oct 6

DTW5:13 pmDetroit Metropolitan Wayne County

4h 20m

1 stop

TYS9:33 pmKnoxville McGhee Tyson

$500

Southwest flights from Knoxville to Detroit

Our best Southwest deals on Knoxville to Detroit flight tickets

Southwest

Oct 29

TYS7:25 pmKnoxville McGhee Tyson

3h 40m

1 stop

DTW11:05 pmDetroit Metropolitan Wayne County

Nov 2

DTW4:50 pmDetroit Metropolitan Wayne County

4h 50m

1 stop

TYS9:40 pmKnoxville McGhee Tyson

$303

Southwest

Jan 8

TYS8:00 amKnoxville McGhee Tyson

4h 25m

1 stop

DTW12:25 pmDetroit Metropolitan Wayne County

Jan 11

DTW6:15 amDetroit Metropolitan Wayne County

5h 55m

1 stop

TYS12:10 pmKnoxville McGhee Tyson

$326

Southwest

Oct 29

TYS8:20 amKnoxville McGhee Tyson

14h 05m

2 stops

DTW10:25 pmDetroit Metropolitan Wayne County

Nov 2

DTW5:00 amDetroit Metropolitan Wayne County

7h 10m

2 stops

TYS12:10 pmKnoxville McGhee Tyson

$352

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 10/22

7:45 am-8:04 pm

1 stop12h 19m

Detroit Metropolitan Wayne County

Mon 10/26

4:29 pm-5:14 pm

1 stop24h 45m

$203

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 10/22

7:45 am-8:04 pm

1 stop12h 19m

Detroit Metropolitan Wayne County

Mon 10/26

8:25 pm-10:05 am

2 stops37h 40m

$245

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 12/3

9:00 pm-11:11 am

1 stop14h 11m

Detroit Metropolitan Wayne County

Sun 12/6

9:33 pm-8:27 am

1 stop10h 54m

$249

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 10/22

9:05 am-11:29 pm

1 stop14h 24m

Detroit Metropolitan Wayne County

Sat 10/24

11:37 am-9:44 am

2 stops22h 07m

$264

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 10/22

7:45 am-12:39 am

2 stops40h 54m

Detroit Metropolitan Wayne County

Thu 10/29

9:07 pm-12:14 pm

1 stop15h 07m

$274

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 2/25

7:00 am-12:43 am

1 stop17h 43m

Detroit Metropolitan Wayne County

Sun 2/28

6:12 pm-11:26 am

1 stop17h 14m

$279

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 10/29

7:45 am-12:06 pm

2 stops28h 21m

Detroit Metropolitan Wayne County

Mon 11/2

4:29 pm-5:14 pm

1 stop24h 45m

$295

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Fri 1/8

1:57 pm-10:35 am

2 stops20h 38m

Detroit Metropolitan Wayne County

Mon 1/11

7:55 pm-12:10 pm

1 stop16h 15m

$302

Quickest round-trip

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 12/3

5:10 pm-6:52 pm

Nonstop1h 42m

Detroit Metropolitan Wayne County

Sun 12/6

4:43 pm-6:22 pm

Nonstop1h 39m

$367

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Fri 10/16

11:45 am-1:29 pm

Nonstop1h 44m

Detroit Metropolitan Wayne County

Mon 10/19

4:44 pm-6:24 pm

Nonstop1h 40m

$367

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Detroit

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Detroit?

The cheapest month to fly to Detroit from Knoxville is in May. Flight prices, which tend to average around $349, are often lower during this time because this is during the off-season. If you’re not able to fly to Detroit in May, then January is your next best option. Flight prices from Knoxville to Detroit during January average around $399.

What is the cheapest day to depart on your flight to Detroit?

On average, the least expensive day to fly to Detroit from Knoxville is on a Thursday. momondo users have found tickets for Thursday departures for as low as $453. However, this price may fluctuate depending on the airline, the season, and holidays. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from Knoxville to Detroit for around $921.

What is the cheapest time of day to depart on your flight to Detroit?

In the morning is the cheapest time of day to fly from Knoxville to Detroit when you can find flight prices for as low as $503. Flying to Detroit in the morning is an ideal time because this is during off-peak travel hours. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $826 on average. Flights to Detroit from Knoxville in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest Knoxville McGhee Tyson to Detroit flight route?

Fly from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County for the best Knoxville McGhee Tyson - Detroit flight prices

What cabin class options are available on Knoxville to Detroit flights?

There are 4 cabin classes available to choose from on Knoxville to Detroit flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Detroit flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Detroit.

When to book flights from Knoxville to Detroit

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Detroit according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Detroit (TYS to DTT) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Detroit

Best Price Found	$76
Fastest flight time	1h 42m
Direct flights	Every day
Airports in Detroit	1 airport

The best one-way flight to Detroit from Knoxville in the past 72 hours is $76. The best round-trip flight deal from Knoxville to Detroit found on momondo in the last 72 hours is $203.

The fastest flight from Knoxville to Detroit takes 1h 42m

Direct flights go from Knoxville to Detroit every day.

There is 1 airport in Detroit. From Knoxville there are direct flights to Detroit Metropolitan Wayne County (DTW).

Search flight deals

Frequently asked questions about flying from Knoxville to Detroit

How far is Knoxville McGhee Tyson to Detroit by plane?
Knoxville McGhee Tyson and Detroit are 442.8 mi apart from one another. By plane, this route typically takes 1h 42m.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Detroit?
Prices for flights from Knoxville McGhee Tyson Airport to Detroit were last updated today.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Detroit?
The number of operators available for flights from Knoxville McGhee Tyson Airport to Detroit is 1 as of September 2026.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Detroit?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Detroit.
What documentation or ID do you need to fly to Detroit?
The necessary travel and health documents for your Detroit trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Knoxville to Detroit?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Knoxville to Detroit is Canadair (Bombardier) Regional Jet 900 (39.07% of total bookings). The next most popular plane models are Canadair (Bombardier) Regional Jet 700 (35.76%), Airbus A319 (6.62%), and Airbus A320-100/200 (6.62%).
What is the most popular airline from Knoxville to Detroit?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Knoxville to Detroit is Delta (100% of total bookings).

Best airlines flying from Knoxville to Detroit

Compare and see reviews for airlines that fly from Knoxville to Detroit with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $299	Free Cancellation	Rating 7.8 8,603 reviews		Search Delta flights

Delta Flights From Knoxville to Detroit
Delta is one of the most popular airlines flying from Knoxville to Detroit, operating 18 flights/week on average for this route. A good Delta flight deal for Knoxville to Detroit starts from $299 round-trip, up to an average price of $445. Our users have rated Delta at 7.8/10.

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Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Detroit?

It is quick and easy to find Knoxville to Detroit flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Detroit that suits you.

Can I find flights from Knoxville to Detroit with flexible booking policies on momondo?

Yes. All flights to Detroit from Knoxville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Knoxville to Detroit?

Once you have performed a search for Knoxville to Detroit flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to Detroit right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Detroit now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Detroit and let you know when they change.