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Cheap flights from Knoxville to Detroit from $140

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:55 pm - 11:11 amTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
14h 16m1 stop Fort Lauderdale
Multiple Airlines Logo
9:00 am - 8:59 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
11h 59m1 stop Orlando
$236Multiple Airlines
Thu, Dec 3 - Mon, Dec 7
Multiple Airlines Logo
8:55 pm - 11:11 amTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
14h 16m1 stop Fort Lauderdale
Multiple Airlines Logo
9:33 pm - 8:27 amDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
10h 54m1 stop Fort Lauderdale
$239Multiple Airlines
Thu, Dec 3 - Sun, Dec 6
Multiple Airlines Logo
1:57 pm - 1:07 amTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
11h 10m1 stop Orlando
Multiple Airlines Logo
7:55 pm - 12:10 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
16h 15m1 stop Fort Lauderdale
$267Multiple Airlines
Fri, Feb 5 - Mon, Feb 8
Multiple Airlines Logo
9:17 am - 6:46 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
9h 29m1 stop Fort Lauderdale
Multiple Airlines Logo
9:33 pm - 10:37 amDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
13h 04m1 stop Fort Lauderdale
$302Multiple Airlines
Fri, Dec 4 - Fri, Dec 4
Multiple Airlines Logo
1:57 pm - 11:21 amTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
21h 24m1 stop Fort Lauderdale
Multiple Airlines Logo
8:05 pm - 8:59 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
24h 54m1 stop Orlando
$307Multiple Airlines
Tue, Dec 8 - Thu, Dec 10
Multiple Airlines Logo
1:57 pm - 1:07 amTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
11h 10m1 stop Orlando
Multiple Airlines Logo
9:45 pm - 12:10 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
14h 25m2 stops Atlanta Hartsfield-Jackson Fort Lauderdale
$312Multiple Airlines
Fri, Feb 5 - Mon, Feb 8
Multiple Airlines Logo
9:00 am - 1:36 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
52h 36m2 stops Orlando Dallas/Fort Worth
Multiple Airlines Logo
9:33 pm - 1:07 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
15h 34m1 stop Fort Lauderdale
$317Multiple Airlines
Mon, Dec 7 - Mon, Dec 14
Multiple Airlines Logo
9:49 pm - 12:53 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
15h 04m1 stop Orlando Sanford Intl
Multiple Airlines Logo
7:50 am - 8:47 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
12h 57m1 stop Tampa
$317Multiple Airlines
Fri, Dec 11 - Mon, Dec 14
Delta Logo
5:10 pm - 6:52 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
1h 42mnonstop
Delta Logo
7:58 pm - 9:33 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
1h 35mnonstop
$369Delta
Fri, Dec 11 - Mon, Dec 14
Delta Logo
1:04 pm - 2:55 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
1h 51mnonstop
Delta Logo
10:21 am - 12:11 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
1h 50mnonstop
$369Delta
Fri, Feb 5 - Mon, Feb 8

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Delta flights from Knoxville to Detroit Metropolitan Wayne County Airport

Our best Delta deals on Knoxville to Detroit Metropolitan Wayne County Airport flight tickets
Delta
Dec 5
TYS7:10 amKnoxville McGhee Tyson
1h 49m
DTW8:59 amDetroit Metropolitan Wayne County
Jan 18
DTW7:46 pmDetroit Metropolitan Wayne County
1h 45m
TYS9:31 pmKnoxville McGhee Tyson
$369
Delta
Dec 5
TYS5:40 amKnoxville McGhee Tyson
5h 44m
1 stop
DTW11:24 amDetroit Metropolitan Wayne County
Jan 18
DTW7:46 pmDetroit Metropolitan Wayne County
1h 45m
TYS9:31 pmKnoxville McGhee Tyson
$379
Delta
Dec 5
TYS5:40 amKnoxville McGhee Tyson
5h 44m
1 stop
DTW11:24 amDetroit Metropolitan Wayne County
Jan 18
DTW9:00 amDetroit Metropolitan Wayne County
6h 48m
1 stop
TYS3:48 pmKnoxville McGhee Tyson
$389

Southwest flights from Knoxville to Detroit Metropolitan Wayne County Airport

Our best Southwest deals on Knoxville to Detroit Metropolitan Wayne County Airport flight tickets
Southwest
Dec 9
TYS5:15 pmKnoxville McGhee Tyson
4h 10m
1 stop
DTW9:25 pmDetroit Metropolitan Wayne County
Dec 16
DTW1:25 pmDetroit Metropolitan Wayne County
6h 25m
1 stop
TYS7:50 pmKnoxville McGhee Tyson
$355
Southwest
Dec 9
TYS7:55 amKnoxville McGhee Tyson
12h 35m
2 stops
DTW8:30 pmDetroit Metropolitan Wayne County
Dec 16
DTW3:55 pmDetroit Metropolitan Wayne County
4h 55m
1 stop
TYS8:50 pmKnoxville McGhee Tyson
$366
Southwest
Dec 5
TYS2:50 pmKnoxville McGhee Tyson
3h 45m
1 stop
DTW6:35 pmDetroit Metropolitan Wayne County
Dec 6
DTW5:50 amDetroit Metropolitan Wayne County
6h 20m
1 stop
TYS12:10 pmKnoxville McGhee Tyson
$371

momondo Fare Finder

 
Use the filters below to find and compare flights from Knoxville to Detroit Metropolitan Wayne County Airport that are best for you.

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Cheapest round-trip

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 12/3

8:55 pm-11:11 am

1 stop14h 16m

Detroit Metropolitan Wayne County

Mon 12/7

9:00 am-8:59 pm

1 stop11h 59m

$236

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 12/3

8:55 pm-11:11 am

1 stop14h 16m

Detroit Metropolitan Wayne County

Sun 12/6

9:33 pm-8:27 am

1 stop10h 54m

$239

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Fri 2/5

1:57 pm-1:07 am

1 stop11h 10m

Detroit Metropolitan Wayne County

Mon 2/8

7:55 pm-12:10 pm

1 stop16h 15m

$267

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Fri 12/4

9:17 am-6:46 pm

1 stop9h 29m

Detroit Metropolitan Wayne County

Fri 12/4

9:33 pm-10:37 am

1 stop13h 04m

$302

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Tue 12/8

1:57 pm-11:21 am

1 stop21h 24m

Detroit Metropolitan Wayne County

Thu 12/10

8:05 pm-8:59 pm

1 stop24h 54m

$307

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Fri 2/5

1:57 pm-1:07 am

1 stop11h 10m

Detroit Metropolitan Wayne County

Mon 2/8

9:45 pm-12:10 pm

2 stops14h 25m

$312

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Mon 12/7

9:00 am-1:36 pm

2 stops52h 36m

Detroit Metropolitan Wayne County

Mon 12/14

9:33 pm-1:07 pm

1 stop15h 34m

$317

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Fri 12/11

9:49 pm-12:53 pm

1 stop15h 04m

Detroit Metropolitan Wayne County

Mon 12/14

7:50 am-8:47 pm

1 stop12h 57m

$317
Quickest round-trip

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Fri 12/11

5:10 pm-6:52 pm

Nonstop1h 42m

Detroit Metropolitan Wayne County

Mon 12/14

7:58 pm-9:33 pm

Nonstop1h 35m

$369

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Fri 2/5

1:04 pm-2:55 pm

Nonstop1h 51m

Detroit Metropolitan Wayne County

Mon 2/8

10:21 am-12:11 pm

Nonstop1h 50m

$369

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Knoxville to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Detroit Metropolitan Wayne County Airport?

Prices are currently low for flights on this route.

Typical prices usually range from $435 to $625.
The lowest price recently found on this route was $236.

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Knoxville is in May. Flight prices, which tend to average around $339, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of May, then book flights to Detroit Metropolitan Wayne County Airport from Knoxville during February instead. Flights to Detroit Metropolitan Wayne County Airport in February, while not as cheap as those in May, still average around $373.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Knoxville to Detroit Metropolitan Wayne County Airport is on a Thursday when prices can be found for as low as $450. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Tuesday is $928.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Knoxville in the morning is the least expensive time of day to depart. momondo users have found prices as low as $510 when looking at flights departing in the morning. Flights to Detroit Metropolitan Wayne County Airport are more costly in the afternoon, with an average ticket price of $826. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Knoxville McGhee Tyson to Detroit Metropolitan Wayne County flight route?

Fly from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County for the best Knoxville McGhee Tyson - Detroit Metropolitan Wayne County flight prices

What cabin class options are available on Knoxville to Detroit Metropolitan Wayne County Airport flights?

There are 4 cabin classes available to choose from on Knoxville to Detroit Metropolitan Wayne County Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 8% on your flight if you consider stops on a Knoxville to Detroit Metropolitan Wayne County Airport flight.

How have Knoxville to Detroit Metropolitan Wayne County Airport flight prices changed over time?

As of November 2026, prices for Knoxville to Detroit Metropolitan Wayne County Airport flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from Knoxville to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Detroit Metropolitan Wayne County Airport (TYS to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Detroit Metropolitan Wayne County Airport

Best Price Found

$140

Fastest flight time

1h 42m

Direct flights

Every day
The best one-way flight to Detroit Metropolitan Wayne County Airport from Knoxville in the past 72 hours is $140. The best round-trip flight deal from Knoxville to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $236.
The fastest flight from Knoxville to Detroit Metropolitan Wayne County Airport takes 1h 42m
Direct flights go from Knoxville to Detroit Metropolitan Wayne County Airport every day.
Search flight deals

Frequently asked questions about flying from Knoxville to Detroit Metropolitan Wayne County Airport

  • How far is Knoxville McGhee Tyson to Detroit Metropolitan Wayne County by plane?

    A flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County will travel around 433.4 mi. By plane, this route typically takes 1h 42m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Knoxville to Detroit Metropolitan Wayne County Airport?

  • What is the most popular airline from Knoxville to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Knoxville to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Knoxville to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $299Free CancellationRating
7.8
8,700 reviews
Search Delta flights

  • Delta Flights From Knoxville to Detroit Metropolitan Wayne County Airport

    Delta operates around 15 flights from Knoxville to Detroit Metropolitan Wayne County Airport every week. The average price of these flights found in the last 72 hours has been $448, but momondo users have found Delta deals from Knoxville to Detroit Metropolitan Wayne County Airport from as low as $299 round-trip. Delta has been scored 7.8/10 in 8,700 reviews.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Dearborn
Warren
Auburn Hills
Romulus
Troy
Monroe
Southfield
Livonia
Roseville
Novi
Sterling Heights
Port Clinton
Belleville
Port Huron
Dundee
Pontiac
Ypsilanti
Plymouth
Farmington Hills

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Detroit?

Finding the right flight to Detroit from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Detroit quick and easy, saving you time and money.

Can I find flights from Knoxville to Detroit with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Detroit flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Detroit?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Detroit.

I’m not ready to book a flight from Knoxville to Detroit right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Detroit from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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