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Cheap flights from Knoxville to Detroit from $88

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Detroit departing on 10/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:54 am - 11:27 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
12h 33m1 stop Fort Lauderdale
Multiple Airlines Logo
4:23 pm - 10:04 amDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
17h 41m1 stop Fort Lauderdale
$180Multiple Airlines
Wed, Sep 16 - Tue, Sep 22
Multiple Airlines Logo
10:54 am - 11:27 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
12h 33m1 stop Fort Lauderdale
Multiple Airlines Logo
4:23 pm - 4:31 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
24h 08m1 stop Fort Lauderdale
$186Multiple Airlines
Wed, Sep 9 - Wed, Sep 16
Multiple Airlines Logo
1:37 pm - 8:02 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
6h 25m1 stop Washington, D.C. Dulles Intl
Multiple Airlines Logo
4:23 pm - 7:24 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
27h 01m1 stop Fort Lauderdale
$195Multiple Airlines
Thu, Oct 1 - Sun, Oct 4
Multiple Airlines Logo
10:54 am - 11:27 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
12h 33m1 stop Fort Lauderdale
Multiple Airlines Logo
12:56 pm - 8:39 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
7h 43m1 stop Orlando
$197Multiple Airlines
Wed, Sep 16 - Mon, Sep 21
Multiple Airlines Logo
5:38 pm - 11:35 amTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
17h 57m1 stop Orlando Sanford Intl
Multiple Airlines Logo
12:56 pm - 8:39 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
7h 43m1 stop Orlando
$205Multiple Airlines
Thu, Sep 10 - Mon, Sep 14
Multiple Airlines Logo
5:38 pm - 11:35 amTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
17h 57m1 stop Orlando Sanford Intl
Multiple Airlines Logo
3:25 pm - 9:39 amDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
18h 14m2 stops Atlanta Hartsfield-Jackson Tampa
$208Multiple Airlines
Thu, Sep 10 - Mon, Sep 14
Multiple Airlines Logo
10:54 am - 11:27 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
12h 33m1 stop Fort Lauderdale
Multiple Airlines Logo
4:23 pm - 10:04 amDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
17h 41m1 stop Fort Lauderdale
$214Multiple Airlines
Wed, Sep 16 - Wed, Sep 23
Multiple Airlines Logo
10:54 am - 11:27 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
12h 33m1 stop Fort Lauderdale
Multiple Airlines Logo
8:57 pm - 4:43 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
19h 46m1 stop Orlando
$214Multiple Airlines
Thu, Sep 24 - Sun, Sep 27
Delta Logo
11:45 am - 1:29 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
1h 44mnonstop
Delta Logo
8:35 am - 10:18 amDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
1h 43mnonstop
$323Delta
Wed, Sep 9 - Wed, Sep 16
Delta Logo
7:33 am - 9:15 amTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
1h 42mnonstop
Delta Logo
8:35 am - 10:18 amDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
1h 43mnonstop
$323Delta
Wed, Sep 16 - Wed, Sep 23

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Delta flights from Knoxville to Detroit Metropolitan Wayne County Airport

Our best Delta deals on Knoxville to Detroit Metropolitan Wayne County Airport flight tickets
Delta
Aug 25
TYS7:15 amKnoxville McGhee Tyson
1h 46m
DTW9:01 amDetroit Metropolitan Wayne County
Sep 1
DTW4:50 pmDetroit Metropolitan Wayne County
1h 41m
TYS6:31 pmKnoxville McGhee Tyson
$339
Delta
Aug 26
TYS5:22 pmKnoxville McGhee Tyson
1h 46m
DTW7:08 pmDetroit Metropolitan Wayne County
Aug 31
DTW8:40 amDetroit Metropolitan Wayne County
1h 40m
TYS10:20 amKnoxville McGhee Tyson
$341
Delta
Aug 25
TYS6:12 pmKnoxville McGhee Tyson
6h 47m
1 stop
DTW12:59 amDetroit Metropolitan Wayne County
Sep 1
DTW8:50 amDetroit Metropolitan Wayne County
1h 40m
TYS10:30 amKnoxville McGhee Tyson
$349

United Airlines flights from Knoxville to Detroit Metropolitan Wayne County Airport

Our best United Airlines deals on Knoxville to Detroit Metropolitan Wayne County Airport flight tickets
United Airlines
Aug 15
TYS5:45 amKnoxville McGhee Tyson
4h 25m
1 stop
DTW10:10 amDetroit Metropolitan Wayne County
Aug 22
DTW5:25 amDetroit Metropolitan Wayne County
4h 32m
1 stop
TYS9:57 amKnoxville McGhee Tyson
$389
United Airlines
Aug 26
TYS10:40 amKnoxville McGhee Tyson
4h 49m
1 stop
DTW3:29 pmDetroit Metropolitan Wayne County
Aug 30
DTW10:30 amDetroit Metropolitan Wayne County
6h 28m
1 stop
TYS4:58 pmKnoxville McGhee Tyson
$431
United Airlines
Aug 15
TYS6:02 pmKnoxville McGhee Tyson
4h 23m
1 stop
DTW10:25 pmDetroit Metropolitan Wayne County
Aug 16
DTW6:00 amDetroit Metropolitan Wayne County
4h 37m
1 stop
TYS10:37 amKnoxville McGhee Tyson
$464

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from Knoxville to Detroit Metropolitan Wayne County Airport that are best for you.

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Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Wed 9/16

10:54 am-11:27 pm

1 stop12h 33m

Detroit Metropolitan Wayne County

Tue 9/22

4:23 pm-10:04 am

1 stop17h 41m

$180

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Wed 9/9

10:54 am-11:27 pm

1 stop12h 33m

Detroit Metropolitan Wayne County

Wed 9/16

4:23 pm-4:31 pm

1 stop24h 08m

$186

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 10/1

1:37 pm-8:02 pm

1 stop6h 25m

Detroit Metropolitan Wayne County

Sun 10/4

4:23 pm-7:24 pm

1 stop27h 01m

$195

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Wed 9/16

10:54 am-11:27 pm

1 stop12h 33m

Detroit Metropolitan Wayne County

Mon 9/21

12:56 pm-8:39 pm

1 stop7h 43m

$197

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 9/10

5:38 pm-11:35 am

1 stop17h 57m

Detroit Metropolitan Wayne County

Mon 9/14

12:56 pm-8:39 pm

1 stop7h 43m

$205

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 9/10

5:38 pm-11:35 am

1 stop17h 57m

Detroit Metropolitan Wayne County

Mon 9/14

3:25 pm-9:39 am

2 stops18h 14m

$208

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Wed 9/16

10:54 am-11:27 pm

1 stop12h 33m

Detroit Metropolitan Wayne County

Wed 9/23

4:23 pm-10:04 am

1 stop17h 41m

$214

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 9/24

10:54 am-11:27 pm

1 stop12h 33m

Detroit Metropolitan Wayne County

Sun 9/27

8:57 pm-4:43 pm

1 stop19h 46m

$214

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Wed 9/9

11:45 am-1:29 pm

Nonstop1h 44m

Detroit Metropolitan Wayne County

Wed 9/16

8:35 am-10:18 am

Nonstop1h 43m

$323
Quickest round-trip

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Wed 9/16

7:33 am-9:15 am

Nonstop1h 42m

Detroit Metropolitan Wayne County

Wed 9/23

8:35 am-10:18 am

Nonstop1h 43m

$323

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Knoxville to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Detroit Metropolitan Wayne County Airport?

Prices are currently low for flights on this route.

Typical prices usually range from $339 to $597.
The lowest price recently found on this route was $180.

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Knoxville is in May. Flight prices, which tend to average around $339, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of May, then book flights to Detroit Metropolitan Wayne County Airport from Knoxville during January instead. Flights to Detroit Metropolitan Wayne County Airport in January, while not as cheap as those in May, still average around $349.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Knoxville to Detroit Metropolitan Wayne County Airport is on a Thursday when prices can be found for as low as $458. Be sure to avoid booking your departure on a Monday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Monday is $801.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Knoxville in the morning is the least expensive time of day to depart. momondo users have found prices as low as $507 when looking at flights departing in the morning. Flights to Detroit Metropolitan Wayne County Airport are more costly in the afternoon, with an average ticket price of $795. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Knoxville McGhee Tyson to Detroit Metropolitan Wayne County flight route?

Fly from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County for the best Knoxville McGhee Tyson - Detroit Metropolitan Wayne County flight prices

What cabin class options are available on Knoxville to Detroit Metropolitan Wayne County Airport flights?

There are 4 cabin classes available to choose from on Knoxville to Detroit Metropolitan Wayne County Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Detroit Metropolitan Wayne County Airport flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Detroit Metropolitan Wayne County Airport.

How have Knoxville to Detroit Metropolitan Wayne County Airport flight prices changed over time?

As of August 2026, prices for Knoxville to Detroit Metropolitan Wayne County Airport flights are approximately 29% more expensive when compared to flights at the same time last year.

When to book flights from Knoxville to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Detroit Metropolitan Wayne County Airport (TYS to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Detroit Metropolitan Wayne County Airport

Best Price Found

$228

Fastest flight time

1h 42m

Direct flights

Every day
The best one-way flight to Detroit Metropolitan Wayne County Airport from Knoxville in the past 72 hours is $228. The best round-trip flight deal from Knoxville to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $339.
The fastest flight from Knoxville to Detroit Metropolitan Wayne County Airport takes 1h 42m
Direct flights go from Knoxville to Detroit Metropolitan Wayne County Airport every day.
Search flight deals

Frequently asked questions about flying from Knoxville to Detroit Metropolitan Wayne County Airport

  • How far is Knoxville McGhee Tyson to Detroit Metropolitan Wayne County by plane?

    A flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County will travel around 433.4 mi. By plane, this route typically takes 1h 42m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Knoxville to Detroit Metropolitan Wayne County Airport?

  • What is the most popular airline from Knoxville to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Knoxville to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Knoxville to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $299Free CancellationRating
7.8
8,502 reviews
Search Delta flights

  • Delta Flights From Knoxville to Detroit Metropolitan Wayne County Airport

    Delta operates around 19 flights from Knoxville to Detroit Metropolitan Wayne County Airport every week. The average price of these flights found in the last 72 hours has been $439, but momondo users have found Delta deals from Knoxville to Detroit Metropolitan Wayne County Airport from as low as $299 round-trip. Delta has been scored 7.8/10 in 8,502 reviews.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Dearborn
Warren
Romulus
Troy
Southfield
Monroe
Livonia
Novi
Roseville
Port Clinton
Port Huron
Sterling Heights
Dundee
Belleville
Pontiac
Ypsilanti
Howell
Farmington Hills

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Detroit?

Finding the right flight to Detroit from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Detroit quick and easy, saving you time and money.

Can I find flights from Knoxville to Detroit with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Detroit flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Detroit?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Detroit.

I’m not ready to book a flight from Knoxville to Detroit right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Detroit from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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