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Cheap flights from Knoxville to Detroit from $93

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Detroit departing on 3/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
1:00 pm - 2:53 pm
TYS
-
DTW
1h 53mnonstop
Delta Logo
10:20 am - 12:13 pm
DTW
-
TYS
1h 53mnonstop
$299Delta
Thu, Jan 8 - Sun, Jan 11
Multiple Airlines Logo
9:29 am - 7:56 am
TYS
-
DTW
22h 27m3 stops
Multiple Airlines Logo
10:08 pm - 12:05 pm
DTW
-
TYS
13h 57m1 stop
$303Multiple Airlines
Thu, Jan 8 - Sun, Jan 11
Delta Logo
6:10 am - 11:15 am
TYS
-
DTW
5h 05m1 stop
Delta Logo
7:00 pm - 8:47 pm
DTW
-
TYS
1h 47mnonstop
$309Delta
Thu, Jan 8 - Sun, Jan 11
Multiple Airlines Logo
5:23 pm - 11:42 am
TYS
-
DTW
18h 19m1 stop
Multiple Airlines Logo
6:25 am - 9:06 pm
DTW
-
TYS
14h 41m1 stop
$313Multiple Airlines
Sun, Dec 14 - Sun, Dec 21
Multiple Airlines Logo
5:23 pm - 11:42 am
TYS
-
DTW
18h 19m1 stop
Multiple Airlines Logo
7:20 pm - 3:33 pm
DTW
-
TYS
20h 13m2 stops
$314Multiple Airlines
Sun, Dec 14 - Sun, Dec 21
Frontier Logo
4:26 pm - 11:25 am
TYS
-
DTW
18h 59m1 stop
Frontier Logo
10:01 pm - 3:51 pm
DTW
-
TYS
17h 50m1 stop
$315Frontier
Sun, Dec 21 - Sun, Jan 4
Multiple Airlines Logo
8:30 am - 2:34 pm
TYS
-
DTW
30h 04m2 stops
Multiple Airlines Logo
10:55 am - 10:15 am
DTW
-
TYS
23h 20m1 stop
$318Multiple Airlines
Sun, Dec 21 - Sun, Jan 4
Delta Logo
2:37 pm - 6:50 pm
TYS
-
DTW
4h 13m1 stop
Delta Logo
6:04 pm - 11:45 pm
DTW
-
TYS
5h 41m1 stop
$319Delta
Thu, Jan 8 - Sun, Jan 11
Multiple Airlines Logo
9:29 am - 7:56 am
TYS
-
DTW
22h 27m3 stops
Multiple Airlines Logo
6:36 pm - 5:28 pm
DTW
-
TYS
22h 52m2 stops
$332Multiple Airlines
Thu, Jan 8 - Sun, Jan 11
Multiple Airlines Logo
8:30 am - 2:34 pm
TYS
-
DTW
30h 04m2 stops
Multiple Airlines Logo
5:10 am - 12:00 pm
DTW
-
TYS
6h 50m1 stop
$355Multiple Airlines
Sun, Dec 21 - Thu, Dec 25

United Airlines flights from Knoxville to Detroit Metropolitan Wayne County Airport

Our best United Airlines deals on Knoxville to Detroit Metropolitan Wayne County Airport flight tickets
United Airlines
Dec 30
TYS5:45 amKnoxville McGhee Tyson
4h 21m
1 stop
DTW10:06 amDetroit Metropolitan Wayne County
Jan 3
DTW5:45 amDetroit Metropolitan Wayne County
5h 11m
1 stop
TYS10:56 amKnoxville McGhee Tyson
$359
Find similar
United Airlines
Jan 8
TYS2:25 pmKnoxville McGhee Tyson
4h 34m
1 stop
DTW6:59 pmDetroit Metropolitan Wayne County
Jan 11
DTW7:15 amDetroit Metropolitan Wayne County
6h 09m
1 stop
TYS1:24 pmKnoxville McGhee Tyson
$379
Find similar
United Airlines
Jan 8
TYS6:45 amKnoxville McGhee Tyson
11h 07m
2 stops
DTW5:52 pmDetroit Metropolitan Wayne County
Jan 11
DTW7:15 amDetroit Metropolitan Wayne County
6h 09m
1 stop
TYS1:24 pmKnoxville McGhee Tyson
$384
Find similar

Delta flights from Knoxville to Detroit Metropolitan Wayne County Airport

Our best Delta deals on Knoxville to Detroit Metropolitan Wayne County Airport flight tickets
Delta
Jan 8
TYS1:00 pmKnoxville McGhee Tyson
1h 53m
DTW2:53 pmDetroit Metropolitan Wayne County
Jan 11
DTW10:20 amDetroit Metropolitan Wayne County
1h 53m
TYS12:13 pmKnoxville McGhee Tyson
$299
Find similar
Delta
Jan 8
TYS6:10 amKnoxville McGhee Tyson
5h 05m
1 stop
DTW11:15 amDetroit Metropolitan Wayne County
Jan 11
DTW7:00 pmDetroit Metropolitan Wayne County
1h 47m
TYS8:47 pmKnoxville McGhee Tyson
$309
Find similar
Delta
Jan 8
TYS2:37 pmKnoxville McGhee Tyson
4h 13m
1 stop
DTW6:50 pmDetroit Metropolitan Wayne County
Jan 11
DTW6:04 pmDetroit Metropolitan Wayne County
5h 41m
1 stop
TYS11:45 pmKnoxville McGhee Tyson
$319
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from Knoxville to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 1/8

1:00 pm-2:53 pm

Nonstop1h 53m

Detroit Metropolitan Wayne County

Sun 1/11

10:20 am-12:13 pm

Nonstop1h 53m

$299

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 1/8

9:29 am-7:56 am

3 stops22h 27m

Detroit Metropolitan Wayne County

Sun 1/11

10:08 pm-12:05 pm

1 stop13h 57m

$303

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 1/8

6:10 am-11:15 am

1 stop5h 05m

Detroit Metropolitan Wayne County

Sun 1/11

7:00 pm-8:47 pm

Nonstop1h 47m

$309

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sun 12/14

5:23 pm-11:42 am

1 stop18h 19m

Detroit Metropolitan Wayne County

Sun 12/21

6:25 am-9:06 pm

1 stop14h 41m

$313

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sun 12/14

5:23 pm-11:42 am

1 stop18h 19m

Detroit Metropolitan Wayne County

Sun 12/21

7:20 pm-3:33 pm

2 stops20h 13m

$314

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sun 12/21

4:26 pm-11:25 am

1 stop18h 59m

Detroit Metropolitan Wayne County

Sun 1/4

10:01 pm-3:51 pm

1 stop17h 50m

$315

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sun 12/21

8:30 am-2:34 pm

2 stops30h 04m

Detroit Metropolitan Wayne County

Sun 1/4

10:55 am-10:15 am

1 stop23h 20m

$318

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 1/8

2:37 pm-6:50 pm

1 stop4h 13m

Detroit Metropolitan Wayne County

Sun 1/11

6:04 pm-11:45 pm

1 stop5h 41m

$319

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 1/8

9:29 am-7:56 am

3 stops22h 27m

Detroit Metropolitan Wayne County

Sun 1/11

6:36 pm-5:28 pm

2 stops22h 52m

$332

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sun 12/21

8:30 am-2:34 pm

2 stops30h 04m

Detroit Metropolitan Wayne County

Thu 12/25

5:10 am-12:00 pm

1 stop6h 50m

$355

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Knoxville to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Knoxville is in April. Flight prices, which tend to average around $393, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of April, then book flights to Detroit Metropolitan Wayne County Airport from Knoxville during February instead. Flights to Detroit Metropolitan Wayne County Airport in February, while not as cheap as those in April, still average around $399.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Knoxville to Detroit Metropolitan Wayne County Airport is on a Thursday when prices can be found for as low as $401. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Sunday is $904.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Knoxville in the evening is the least expensive time of day to depart. momondo users have found prices as low as $423 when looking at flights departing in the evening. Flights to Detroit Metropolitan Wayne County Airport are more costly at noon, with an average ticket price of $645. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Knoxville McGhee Tyson to Detroit Metropolitan Wayne County flight route?

Fly from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County for the best Knoxville McGhee Tyson - Detroit Metropolitan Wayne County flight prices

What cabin class options are available on Knoxville McGhee Tyson to Detroit Metropolitan Wayne County flights?

There are 4 cabin classes available to choose from on Knoxville McGhee Tyson to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 8% on your flight if you consider stops on a Knoxville to Detroit Metropolitan Wayne County Airport flight.

How have Knoxville to Detroit Metropolitan Wayne County Airport flight prices changed over time?

As of December 2025, prices for Knoxville to Detroit Metropolitan Wayne County Airport flights are approximately 209% more expensive when compared to flights at the same time last year.

When to book flights from Knoxville to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Detroit Metropolitan Wayne County Airport (TYS to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Detroit Metropolitan Wayne County Airport

Best Price Found

$278

Fastest flight time

1h 41m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun
The best one-way flight to Detroit Metropolitan Wayne County Airport from Knoxville in the past 72 hours is $278. The best round-trip flight deal from Knoxville to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $439.
The fastest flight from Knoxville to Detroit Metropolitan Wayne County Airport takes 1h 41m
Direct flights go from Knoxville to Detroit Metropolitan Wayne County Airport on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
Search flight deals

  • How far is Knoxville McGhee Tyson to Detroit Metropolitan Wayne County by plane?

    A flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County will travel around 433.4 mi. By plane, this route typically takes 1h 46m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Knoxville to Detroit Metropolitan Wayne County Airport?

  • What is the most popular airline from Knoxville to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Knoxville to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Knoxville to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $158Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights
DeltaPriceFrom $299Free CancellationRating
7.9
8,013 reviews
Search Delta flights

  • Delta Flights From Knoxville to Detroit Metropolitan Wayne County Airport

    Delta operates around 15 flights from Knoxville to Detroit Metropolitan Wayne County Airport every week. The average price of these flights found in the last 72 hours has been $430, but momondo users have found Delta deals from Knoxville to Detroit Metropolitan Wayne County Airport from as low as $299 round-trip. Delta has been scored 7.9/10 in 8,013 reviews.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Troy
Romulus
Dearborn
Southfield
Monroe
Novi
Livonia
Port Clinton
Port Huron
Roseville
Sterling Heights
Brighton
Ypsilanti
Pontiac
Dundee
Madison Heights
Royal Oak

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Detroit?

Finding the right flight to Detroit from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Detroit quick and easy, saving you time and money.

Can I find flights from Knoxville to Detroit with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Detroit flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Detroit?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Detroit.

I’m not ready to book a flight from Knoxville to Detroit right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Detroit from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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