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Cheap flights from Knoxville to Detroit from $89

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Detroit departing on 10/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Detroit

Cheap round-trip flights

Frontier Logo
8:17 pm - 12:59 amTYS-DTW
28h 42m1 stop
Frontier Logo
6:00 am - 7:32 pmDTW-TYS
13h 32m1 stop
$184Frontier
Find Deal
Fri, Oct 24 - Sun, Oct 26
Logo
4:12 pm - 11:29 pmTYS-DTW
7h 17m1 stop
Logo
10:08 am - 9:55 pmDTW-TYS
11h 47m1 stop
$220
Find Deal
Sat, Nov 1 - Mon, Nov 3
Logo
7:15 am - 6:44 pmTYS-DTW
11h 29m1 stop
Logo
10:08 am - 9:55 pmDTW-TYS
11h 47m1 stop
$224
Find Deal
Fri, Oct 24 - Mon, Nov 3
Logo
7:30 am - 7:57 amTYS-DTW
24h 27m1 stop
Logo
9:19 pm - 3:41 pmDTW-TYS
18h 22m2 stops
$225
Find Deal
Tue, Sep 9 - Tue, Sep 16
Logo
1:22 pm - 10:40 pmTYS-DTW
9h 18m1 stop
Logo
8:49 pm - 12:55 pmDTW-TYS
16h 06m1 stop
$226
Find Deal
Fri, Sep 12 - Mon, Sep 15
Logo
8:49 pm - 10:53 pmTYS-DTW
26h 04m2 stops
Logo
8:49 pm - 12:55 pmDTW-TYS
16h 06m1 stop
$227
Find Deal
Fri, Sep 12 - Mon, Sep 15
American Airlines Logo
7:14 am - 2:47 pmTYS-DTW
7h 33m1 stop
American Airlines Logo
12:39 pm - 9:00 pmDTW-TYS
8h 21m1 stop
$269American Airlines
Find Deal
Wed, Sep 10 - Tue, Sep 16
American Airlines Logo
3:10 pm - 11:21 pmTYS-DTW
8h 11m1 stop
American Airlines Logo
6:00 am - 10:32 amDTW-TYS
4h 32m1 stop
$294American Airlines
Find Deal
Sat, Sep 13 - Sun, Sep 14
Delta Logo
7:49 am - 9:30 amTYS-DTW
1h 41mnonstop
Delta Logo
7:45 pm - 9:19 pmDTW-TYS
1h 34mnonstop
$299Delta
Find Deal
Sat, Sep 13 - Mon, Sep 15
Delta Logo
6:08 pm - 10:01 pmTYS-DTW
3h 53m1 stop
Delta Logo
4:50 pm - 6:23 pmDTW-TYS
1h 33mnonstop
$309Delta
Find Deal
Sat, Sep 13 - Sat, Sep 20

Frontier flights from Knoxville to Detroit Metropolitan Wayne County Airport

Our best Frontier deals on Knoxville to Detroit Metropolitan Wayne County Airport flight tickets
Frontier
Oct 24
TYS8:17 pmKnoxville McGhee Tyson
28h 42m
1 stop
DTW12:59 amDetroit Metropolitan Wayne County
Oct 26
DTW6:00 amDetroit Metropolitan Wayne County
13h 32m
1 stop
TYS7:32 pmKnoxville McGhee Tyson
$184
Find similar
Frontier
Sep 18
TYS8:40 pmKnoxville McGhee Tyson
28h 06m
1 stop
DTW12:46 amDetroit Metropolitan Wayne County
Sep 21
DTW6:10 amDetroit Metropolitan Wayne County
10h 08m
1 stop
TYS4:18 pmKnoxville McGhee Tyson
$232
Find similar
Frontier
Oct 24
TYS8:17 pmKnoxville McGhee Tyson
15h 00m
2 stops
DTW11:17 amDetroit Metropolitan Wayne County
Oct 26
DTW6:00 amDetroit Metropolitan Wayne County
13h 32m
1 stop
TYS7:32 pmKnoxville McGhee Tyson
$236
Find similar

American Airlines flights from Knoxville to Detroit Metropolitan Wayne County Airport

Our best American Airlines deals on Knoxville to Detroit Metropolitan Wayne County Airport flight tickets
American Airlines
Sep 10
TYS7:14 amKnoxville McGhee Tyson
7h 33m
1 stop
DTW2:47 pmDetroit Metropolitan Wayne County
Sep 16
DTW12:39 pmDetroit Metropolitan Wayne County
8h 21m
1 stop
TYS9:00 pmKnoxville McGhee Tyson
$269
Find similar
American Airlines
Sep 13
TYS3:10 pmKnoxville McGhee Tyson
8h 11m
1 stop
DTW11:21 pmDetroit Metropolitan Wayne County
Sep 14
DTW6:00 amDetroit Metropolitan Wayne County
4h 32m
1 stop
TYS10:32 amKnoxville McGhee Tyson
$294
Find similar
American Airlines
Sep 13
TYS3:10 pmKnoxville McGhee Tyson
8h 11m
1 stop
DTW11:21 pmDetroit Metropolitan Wayne County
Sep 20
DTW12:24 pmDetroit Metropolitan Wayne County
8h 36m
1 stop
TYS9:00 pmKnoxville McGhee Tyson
$295
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from Knoxville to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Fri 10/24

8:17 pm-12:59 am

1 stop28h 42m

Detroit Metropolitan Wayne County

Sun 10/26

6:00 am-7:32 pm

1 stop13h 32m

$184

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 11/1

4:12 pm-11:29 pm

1 stop7h 17m

Detroit Metropolitan Wayne County

Mon 11/3

10:08 am-9:55 pm

1 stop11h 47m

$220

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Fri 10/24

7:15 am-6:44 pm

1 stop11h 29m

Detroit Metropolitan Wayne County

Mon 11/3

10:08 am-9:55 pm

1 stop11h 47m

$224

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Tue 9/9

7:30 am-7:57 am

1 stop24h 27m

Detroit Metropolitan Wayne County

Tue 9/16

9:19 pm-3:41 pm

2 stops18h 22m

$225

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Fri 9/12

1:22 pm-10:40 pm

1 stop9h 18m

Detroit Metropolitan Wayne County

Mon 9/15

8:49 pm-12:55 pm

1 stop16h 06m

$226

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Fri 9/12

8:49 pm-10:53 pm

2 stops26h 04m

Detroit Metropolitan Wayne County

Mon 9/15

8:49 pm-12:55 pm

1 stop16h 06m

$227

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Wed 9/10

7:14 am-2:47 pm

1 stop7h 33m

Detroit Metropolitan Wayne County

Tue 9/16

12:39 pm-9:00 pm

1 stop8h 21m

$269

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 9/13

3:10 pm-11:21 pm

1 stop8h 11m

Detroit Metropolitan Wayne County

Sun 9/14

6:00 am-10:32 am

1 stop4h 32m

$294

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 9/13

7:49 am-9:30 am

Nonstop1h 41m

Detroit Metropolitan Wayne County

Mon 9/15

7:45 pm-9:19 pm

Nonstop1h 34m

$299

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 9/13

6:08 pm-10:01 pm

1 stop3h 53m

Detroit Metropolitan Wayne County

Sat 9/20

4:50 pm-6:23 pm

Nonstop1h 33m

$309

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Knoxville to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Knoxville is in December. Flight prices, which tend to average around $376, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of December, then book flights to Detroit Metropolitan Wayne County Airport from Knoxville during April instead. Flights to Detroit Metropolitan Wayne County Airport in April, while not as cheap as those in December, still average around $393.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Knoxville to Detroit Metropolitan Wayne County Airport is on a Thursday when prices can be found for as low as $402. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Sunday is $833.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Knoxville in the evening is the least expensive time of day to depart. momondo users have found prices as low as $423 when looking at flights departing in the evening. Flights to Detroit Metropolitan Wayne County Airport are more costly at noon, with an average ticket price of $896. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Knoxville McGhee Tyson to Detroit Metropolitan Wayne County flight route?

Fly from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County for the best Knoxville McGhee Tyson - Detroit Metropolitan Wayne County flight prices

What cabin class options are available on Knoxville McGhee Tyson to Detroit Metropolitan Wayne County flights?

There are 4 cabin classes available to choose from on Knoxville McGhee Tyson to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 52% on your flight if you consider stops on a Knoxville to Detroit Metropolitan Wayne County Airport flight.

How have Knoxville to Detroit Metropolitan Wayne County Airport flight prices changed over time?

As of August 2025, prices for Knoxville to Detroit Metropolitan Wayne County Airport flights are approximately 27% cheaper when compared to flights at the same time last year.

When to book flights from Knoxville to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Detroit Metropolitan Wayne County Airport (TYS to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Detroit Metropolitan Wayne County Airport

Best Price Found

$89

Fastest flight time

1h 41m

Direct flights

Every day
The best one-way flight to Detroit Metropolitan Wayne County Airport from Knoxville in the past 72 hours is $89. The best round-trip flight deal from Knoxville to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $184.
The fastest flight from Knoxville to Detroit Metropolitan Wayne County Airport takes 1h 41m
Direct flights go from Knoxville to Detroit Metropolitan Wayne County Airport every day.
Search flight deals

  • How far is Knoxville McGhee Tyson to Detroit Metropolitan Wayne County by plane?

    A flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County will travel around 433.4 mi. By plane, this route typically takes 1h 41m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Knoxville to Detroit Metropolitan Wayne County Airport?

  • What is the most popular airline from Knoxville to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Knoxville to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Knoxville to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $309Free CancellationRating
8.0
7,985 reviews
Search Delta flights
American AirlinesPriceFrom $318Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

  • Delta Flights From Knoxville to Detroit Metropolitan Wayne County Airport

    Delta operates around 5 flights from Knoxville to Detroit Metropolitan Wayne County Airport every week. The average price of these flights found in the last 72 hours has been $459, but momondo users have found Delta deals from Knoxville to Detroit Metropolitan Wayne County Airport from as low as $309 round-trip. Delta has been scored 8.0/10 in 7,985 reviews.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Monroe
Southfield
Troy
Novi
Dearborn
Livonia
Romulus
Port Huron
Port Clinton
Sterling Heights
Roseville
Brighton
Pontiac
Madison Heights
Ypsilanti
Belleville
Farmington Hills

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Detroit?

Finding the right flight to Detroit from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Detroit quick and easy, saving you time and money.

Can I find flights from Knoxville to Detroit with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Detroit flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Detroit?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Detroit.

I’m not ready to book a flight from Knoxville to Detroit right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Detroit from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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