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Cheap flights from Knoxville to Detroit from $89

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Detroit departing on 11/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Multiple Airlines Logo
7:30 am - 6:00 pmTYS-DTW
10h 30m1 stop
Multiple Airlines Logo
7:17 pm - 12:57 pmDTW-TYS
17h 40m1 stop
$188Multiple Airlines
Find Deal
Sat, Nov 15 - Tue, Nov 18
Multiple Airlines Logo
6:51 pm - 8:38 amTYS-DTW
13h 47m1 stop
Multiple Airlines Logo
12:24 pm - 9:55 pmDTW-TYS
9h 31m1 stop
$213Multiple Airlines
Find Deal
Thu, Oct 30 - Mon, Nov 3
Multiple Airlines Logo
7:30 am - 2:03 pmTYS-DTW
6h 33m1 stop
Multiple Airlines Logo
12:58 pm - 1:01 pmDTW-TYS
24h 03m1 stop
$217Multiple Airlines
Find Deal
Tue, Nov 11 - Fri, Nov 14
Multiple Airlines Logo
7:30 am - 2:03 pmTYS-DTW
6h 33m1 stop
Multiple Airlines Logo
7:28 pm - 10:56 pmDTW-TYS
27h 28m1 stop
$218Multiple Airlines
Find Deal
Tue, Nov 11 - Thu, Nov 13
Multiple Airlines Logo
6:00 am - 11:59 pmTYS-DTW
17h 59m1 stop
Multiple Airlines Logo
10:51 am - 10:52 pmDTW-TYS
12h 01m1 stop
$221Multiple Airlines
Find Deal
Thu, Nov 20 - Mon, Nov 24
Multiple Airlines Logo
7:30 am - 6:00 pmTYS-DTW
10h 30m1 stop
Multiple Airlines Logo
10:45 am - 12:57 pmDTW-TYS
26h 12m2 stops
$223Multiple Airlines
Find Deal
Sat, Nov 15 - Tue, Nov 18
Multiple Airlines Logo
2:22 pm - 5:12 pmTYS-DTW
26h 50m2 stops
Multiple Airlines Logo
10:51 am - 10:52 pmDTW-TYS
12h 01m1 stop
$226Multiple Airlines
Find Deal
Mon, Nov 17 - Mon, Nov 24
Multiple Airlines Logo
1:05 pm - 11:17 pmTYS-DTW
10h 12m1 stop
Multiple Airlines Logo
8:30 pm - 4:02 pmDTW-TYS
19h 32m1 stop
$227Multiple Airlines
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Fri, Dec 12 - Mon, Dec 15
Delta Logo
12:50 pm - 2:36 pmTYS-DTW
1h 46mnonstop
Delta Logo
6:20 pm - 8:00 pmDTW-TYS
1h 40mnonstop
$299Delta
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Fri, Dec 12 - Sun, Dec 14
American Airlines Logo
8:06 am - 6:33 pmTYS-DTW
10h 27m1 stop
American Airlines Logo
2:03 pm - 9:42 pmDTW-TYS
7h 39m1 stop
$303American Airlines
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Sat, Dec 13 - Sun, Jan 18

Delta flights from Knoxville to Detroit Metropolitan Wayne County Airport

Our best Delta deals on Knoxville to Detroit Metropolitan Wayne County Airport flight tickets
Delta
Dec 12
TYS12:50 pmKnoxville McGhee Tyson
1h 46m
DTW2:36 pmDetroit Metropolitan Wayne County
Dec 14
DTW6:20 pmDetroit Metropolitan Wayne County
1h 40m
TYS8:00 pmKnoxville McGhee Tyson
$299
Find similar
Delta
Nov 4
TYS7:45 amKnoxville McGhee Tyson
1h 45m
DTW9:30 amDetroit Metropolitan Wayne County
Nov 12
DTW5:45 amDetroit Metropolitan Wayne County
5h 00m
1 stop
TYS10:45 amKnoxville McGhee Tyson
$379
Find similar
Delta
Oct 25
TYS7:45 amKnoxville McGhee Tyson
1h 45m
DTW9:30 amDetroit Metropolitan Wayne County
Oct 27
DTW7:35 pmDetroit Metropolitan Wayne County
1h 38m
TYS9:13 pmKnoxville McGhee Tyson
$499
Find similar

United Airlines flights from Knoxville to Detroit Metropolitan Wayne County Airport

Our best United Airlines deals on Knoxville to Detroit Metropolitan Wayne County Airport flight tickets
United Airlines
Oct 23
TYS7:26 pmKnoxville McGhee Tyson
4h 31m
1 stop
DTW11:57 pmDetroit Metropolitan Wayne County
Oct 26
DTW5:45 amDetroit Metropolitan Wayne County
5h 03m
1 stop
TYS10:48 amKnoxville McGhee Tyson
$479
Find similar
United Airlines
Oct 23
TYS2:16 pmKnoxville McGhee Tyson
4h 41m
1 stop
DTW6:57 pmDetroit Metropolitan Wayne County
Oct 26
DTW2:10 pmDetroit Metropolitan Wayne County
9h 49m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$484
Find similar
United Airlines
Oct 23
TYS7:00 amKnoxville McGhee Tyson
6h 12m
1 stop
DTW1:12 pmDetroit Metropolitan Wayne County
Oct 25
DTW7:41 pmDetroit Metropolitan Wayne County
4h 11m
1 stop
TYS11:52 pmKnoxville McGhee Tyson
$489
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momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Knoxville to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 11/15

7:30 am-6:00 pm

1 stop10h 30m

Detroit Metropolitan Wayne County

Tue 11/18

7:17 pm-12:57 pm

1 stop17h 40m

$188

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 10/30

6:51 pm-8:38 am

1 stop13h 47m

Detroit Metropolitan Wayne County

Mon 11/3

12:24 pm-9:55 pm

1 stop9h 31m

$213

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Tue 11/11

7:30 am-2:03 pm

1 stop6h 33m

Detroit Metropolitan Wayne County

Fri 11/14

12:58 pm-1:01 pm

1 stop24h 03m

$217

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Tue 11/11

7:30 am-2:03 pm

1 stop6h 33m

Detroit Metropolitan Wayne County

Thu 11/13

7:28 pm-10:56 pm

1 stop27h 28m

$218

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 11/20

6:00 am-11:59 pm

1 stop17h 59m

Detroit Metropolitan Wayne County

Mon 11/24

10:51 am-10:52 pm

1 stop12h 01m

$221

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 11/15

7:30 am-6:00 pm

1 stop10h 30m

Detroit Metropolitan Wayne County

Tue 11/18

10:45 am-12:57 pm

2 stops26h 12m

$223

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Mon 11/17

2:22 pm-5:12 pm

2 stops26h 50m

Detroit Metropolitan Wayne County

Mon 11/24

10:51 am-10:52 pm

1 stop12h 01m

$226

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Fri 12/12

1:05 pm-11:17 pm

1 stop10h 12m

Detroit Metropolitan Wayne County

Mon 12/15

8:30 pm-4:02 pm

1 stop19h 32m

$227

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Fri 12/12

12:50 pm-2:36 pm

Nonstop1h 46m

Detroit Metropolitan Wayne County

Sun 12/14

6:20 pm-8:00 pm

Nonstop1h 40m

$299

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 12/13

8:06 am-6:33 pm

1 stop10h 27m

Detroit Metropolitan Wayne County

Sun 1/18

2:03 pm-9:42 pm

1 stop7h 39m

$303

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Knoxville to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Knoxville is in December. Flight prices, which tend to average around $374, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of December, then book flights to Detroit Metropolitan Wayne County Airport from Knoxville during April instead. Flights to Detroit Metropolitan Wayne County Airport in April, while not as cheap as those in December, still average around $393.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Knoxville to Detroit Metropolitan Wayne County Airport is on a Thursday when prices can be found for as low as $398. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Sunday is $904.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Knoxville in the evening is the least expensive time of day to depart. momondo users have found prices as low as $423 when looking at flights departing in the evening. Flights to Detroit Metropolitan Wayne County Airport are more costly at noon, with an average ticket price of $691. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Knoxville McGhee Tyson to Detroit Metropolitan Wayne County flight route?

Fly from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County for the best Knoxville McGhee Tyson - Detroit Metropolitan Wayne County flight prices

What cabin class options are available on Knoxville McGhee Tyson to Detroit Metropolitan Wayne County flights?

There are 4 cabin classes available to choose from on Knoxville McGhee Tyson to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 35% on your flight if you consider stops on a Knoxville to Detroit Metropolitan Wayne County Airport flight.

How have Knoxville to Detroit Metropolitan Wayne County Airport flight prices changed over time?

As of October 2025, prices for Knoxville to Detroit Metropolitan Wayne County Airport flights are approximately 35% more expensive when compared to flights at the same time last year.

When to book flights from Knoxville to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Detroit Metropolitan Wayne County Airport (TYS to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Detroit Metropolitan Wayne County Airport

Best Price Found

$358

Fastest flight time

1h 43m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun
The best one-way flight to Detroit Metropolitan Wayne County Airport from Knoxville in the past 72 hours is $358. The best round-trip flight deal from Knoxville to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $338.
The fastest flight from Knoxville to Detroit Metropolitan Wayne County Airport takes 1h 43m
Direct flights go from Knoxville to Detroit Metropolitan Wayne County Airport on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
Search flight deals

  • How far is Knoxville McGhee Tyson to Detroit Metropolitan Wayne County by plane?

    A flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County will travel around 433.4 mi. By plane, this route typically takes 1h 46m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Knoxville to Detroit Metropolitan Wayne County Airport?

  • What is the most popular airline from Knoxville to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Knoxville to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Knoxville to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $318Free CancellationRating
7.2
11,029 reviews
Search American Airlines flights
DeltaPriceFrom $319Free CancellationRating
7.9
7,981 reviews
Search Delta flights

  • Delta Flights From Knoxville to Detroit Metropolitan Wayne County Airport

    Delta operates around 11 flights from Knoxville to Detroit Metropolitan Wayne County Airport every week. The average price of these flights found in the last 72 hours has been $428, but momondo users have found Delta deals from Knoxville to Detroit Metropolitan Wayne County Airport from as low as $319 round-trip. Delta has been scored 7.9/10 in 7,981 reviews.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Southfield
Troy
Monroe
Dearborn
Romulus
Novi
Livonia
Port Clinton
Port Huron
Sterling Heights
Roseville
Brighton
Ypsilanti
Pontiac
Madison Heights
Dundee
Royal Oak

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Detroit?

Finding the right flight to Detroit from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Detroit quick and easy, saving you time and money.

Can I find flights from Knoxville to Detroit with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Detroit flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Detroit?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Detroit.

I’m not ready to book a flight from Knoxville to Detroit right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Detroit from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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