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Cheap flights from Knoxville to Detroit from $76

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:37 pm - 11:37 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
30h 00m1 stop Fort Lauderdale
Multiple Airlines Logo
4:29 pm - 5:18 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
24h 49m1 stop Fort Lauderdale
$254Multiple Airlines
Thu, Nov 5 - Mon, Nov 9
Multiple Airlines Logo
7:45 am - 9:43 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
13h 58m2 stops Washington, D.C. Dulles Intl Dallas/Fort Worth
Multiple Airlines Logo
4:29 pm - 5:18 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
24h 49m1 stop Fort Lauderdale
$255Multiple Airlines
Thu, Nov 5 - Mon, Nov 9
Multiple Airlines Logo
7:45 am - 12:39 amTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
40h 54m2 stops Washington, D.C. Dulles Intl Atlanta Hartsfield-Jackson
Multiple Airlines Logo
9:07 pm - 12:14 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
15h 07m1 stop Orlando
$274Multiple Airlines
Thu, Oct 22 - Thu, Oct 29
Multiple Airlines Logo
7:00 am - 12:43 amTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
17h 43m1 stop Tampa St. Petersburg
Multiple Airlines Logo
6:12 pm - 11:26 amDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
17h 14m1 stop Tampa
$279Multiple Airlines
Thu, Feb 25 - Sun, Feb 28
Multiple Airlines Logo
2:38 pm - 11:37 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
8h 59m1 stop Fort Lauderdale
Multiple Airlines Logo
5:49 pm - 1:31 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
19h 42m1 stop Orlando
$291Multiple Airlines
Fri, Nov 13 - Sun, Nov 15
Multiple Airlines Logo
7:00 am - 11:40 amTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
28h 40m1 stop Orlando
Multiple Airlines Logo
4:29 pm - 5:14 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
24h 45m1 stop Fort Lauderdale
$301Multiple Airlines
Mon, Oct 26 - Mon, Nov 2
Southwest Logo
5:15 pm - 9:25 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
4h 10m1 stop Nashville Intl
Southwest Logo
4:50 pm - 9:45 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
4h 55m1 stop Baltimore/Washington
$303Southwest
Tue, Nov 10 - Thu, Nov 12
Southwest Logo
8:15 am - 1:00 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
4h 45m1 stop Baltimore/Washington
Southwest Logo
5:50 am - 12:10 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
6h 20m1 stop Nashville Intl
$303Southwest
Sat, Nov 7 - Mon, Nov 9
Delta Logo
11:45 am - 1:29 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
1h 44mnonstop
Delta Logo
4:44 pm - 6:24 pmDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
1h 40mnonstop
$367Delta
Fri, Oct 16 - Mon, Oct 19
Delta Logo
5:18 pm - 7:01 pmTYS  Knoxville McGhee Tyson-DTW Detroit Metropolitan Wayne County
1h 43mnonstop
Delta Logo
8:40 am - 10:20 amDTW  Detroit Metropolitan Wayne County-TYS Knoxville McGhee Tyson
1h 40mnonstop
$367Delta
Fri, Oct 16 - Mon, Oct 19

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Delta flights from Knoxville to Detroit Metropolitan Wayne County Airport

Our best Delta deals on Knoxville to Detroit Metropolitan Wayne County Airport flight tickets
Delta
Dec 21
TYS7:25 amKnoxville McGhee Tyson
1h 49m
DTW9:14 amDetroit Metropolitan Wayne County
Dec 31
DTW7:55 pmDetroit Metropolitan Wayne County
1h 35m
TYS9:30 pmKnoxville McGhee Tyson
$367
Delta
Dec 21
TYS6:00 amKnoxville McGhee Tyson
4h 36m
1 stop
DTW10:36 amDetroit Metropolitan Wayne County
Dec 31
DTW7:55 pmDetroit Metropolitan Wayne County
1h 35m
TYS9:30 pmKnoxville McGhee Tyson
$377
Delta
Oct 16
TYS4:57 pmKnoxville McGhee Tyson
4h 14m
1 stop
DTW9:11 pmDetroit Metropolitan Wayne County
Oct 19
DTW6:25 amDetroit Metropolitan Wayne County
4h 29m
1 stop
TYS10:54 amKnoxville McGhee Tyson
$387

Southwest flights from Knoxville to Detroit Metropolitan Wayne County Airport

Our best Southwest deals on Knoxville to Detroit Metropolitan Wayne County Airport flight tickets
Southwest
Nov 7
TYS8:15 amKnoxville McGhee Tyson
4h 45m
1 stop
DTW1:00 pmDetroit Metropolitan Wayne County
Nov 9
DTW5:50 amDetroit Metropolitan Wayne County
6h 20m
1 stop
TYS12:10 pmKnoxville McGhee Tyson
$303
Southwest
Nov 7
TYS8:15 amKnoxville McGhee Tyson
4h 45m
1 stop
DTW1:00 pmDetroit Metropolitan Wayne County
Nov 9
DTW5:00 amDetroit Metropolitan Wayne County
7h 10m
2 stops
TYS12:10 pmKnoxville McGhee Tyson
$308
Southwest
Nov 7
TYS8:15 amKnoxville McGhee Tyson
9h 15m
2 stops
DTW5:30 pmDetroit Metropolitan Wayne County
Nov 9
DTW5:00 amDetroit Metropolitan Wayne County
7h 10m
2 stops
TYS12:10 pmKnoxville McGhee Tyson
$313

momondo Fare Finder

 
Use the filters below to find and compare flights from Knoxville to Detroit Metropolitan Wayne County Airport that are best for you.

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Cheapest round-trip

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 11/5

5:37 pm-11:37 pm

1 stop30h 00m

Detroit Metropolitan Wayne County

Mon 11/9

4:29 pm-5:18 pm

1 stop24h 49m

$254

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 11/5

7:45 am-9:43 pm

2 stops13h 58m

Detroit Metropolitan Wayne County

Mon 11/9

4:29 pm-5:18 pm

1 stop24h 49m

$255

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 10/22

7:45 am-12:39 am

2 stops40h 54m

Detroit Metropolitan Wayne County

Thu 10/29

9:07 pm-12:14 pm

1 stop15h 07m

$274

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Thu 2/25

7:00 am-12:43 am

1 stop17h 43m

Detroit Metropolitan Wayne County

Sun 2/28

6:12 pm-11:26 am

1 stop17h 14m

$279

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Fri 11/13

2:38 pm-11:37 pm

1 stop8h 59m

Detroit Metropolitan Wayne County

Sun 11/15

5:49 pm-1:31 pm

1 stop19h 42m

$291

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Mon 10/26

7:00 am-11:40 am

1 stop28h 40m

Detroit Metropolitan Wayne County

Mon 11/2

4:29 pm-5:14 pm

1 stop24h 45m

$301

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Tue 11/10

5:15 pm-9:25 pm

1 stop4h 10m

Detroit Metropolitan Wayne County

Thu 11/12

4:50 pm-9:45 pm

1 stop4h 55m

$303

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Sat 11/7

8:15 am-1:00 pm

1 stop4h 45m

Detroit Metropolitan Wayne County

Mon 11/9

5:50 am-12:10 pm

1 stop6h 20m

$303

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Fri 10/16

11:45 am-1:29 pm

Nonstop1h 44m

Detroit Metropolitan Wayne County

Mon 10/19

4:44 pm-6:24 pm

Nonstop1h 40m

$367
Quickest round-trip

KnoxvilleDetroit

TYS Knoxville McGhee Tyson - DTW Detroit Metropolitan Wayne County

TYSDTW

Knoxville McGhee Tyson

Fri 10/16

5:18 pm-7:01 pm

Nonstop1h 43m

Detroit Metropolitan Wayne County

Mon 10/19

8:40 am-10:20 am

Nonstop1h 40m

$367

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Knoxville to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Detroit Metropolitan Wayne County Airport?

Prices are currently low for flights on this route.

Typical prices usually range from $345 to $469.
The lowest price recently found on this route was $254.

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Knoxville is in May. Flight prices, which tend to average around $339, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of May, then book flights to Detroit Metropolitan Wayne County Airport from Knoxville during January instead. Flights to Detroit Metropolitan Wayne County Airport in January, while not as cheap as those in May, still average around $349.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Knoxville to Detroit Metropolitan Wayne County Airport is on a Thursday when prices can be found for as low as $454. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Tuesday is $922.

What is the cheapest time of day to depart on your flight to Detroit Metropolitan Wayne County Airport?

Flying to Detroit Metropolitan Wayne County Airport from Knoxville in the morning is the least expensive time of day to depart. momondo users have found prices as low as $502 when looking at flights departing in the morning. Flights to Detroit Metropolitan Wayne County Airport are more costly in the afternoon, with an average ticket price of $825. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Knoxville McGhee Tyson to Detroit Metropolitan Wayne County flight route?

Fly from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County for the best Knoxville McGhee Tyson - Detroit Metropolitan Wayne County flight prices

What cabin class options are available on Knoxville to Detroit Metropolitan Wayne County Airport flights?

There are 4 cabin classes available to choose from on Knoxville to Detroit Metropolitan Wayne County Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Knoxville to Detroit Metropolitan Wayne County Airport flights?

No. A direct flight is the cheapest option for a flight between Knoxville to Detroit Metropolitan Wayne County Airport.

How have Knoxville to Detroit Metropolitan Wayne County Airport flight prices changed over time?

As of September 2026, prices for Knoxville to Detroit Metropolitan Wayne County Airport flights are approximately 9% cheaper when compared to flights at the same time last year.

When to book flights from Knoxville to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Detroit Metropolitan Wayne County Airport (TYS to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Detroit Metropolitan Wayne County Airport

Best Price Found

$76

Fastest flight time

1h 44m

Direct flights

Every day
The best one-way flight to Detroit Metropolitan Wayne County Airport from Knoxville in the past 72 hours is $76. The best round-trip flight deal from Knoxville to Detroit Metropolitan Wayne County Airport found on momondo in the last 72 hours is $254.
The fastest flight from Knoxville to Detroit Metropolitan Wayne County Airport takes 1h 44m
Direct flights go from Knoxville to Detroit Metropolitan Wayne County Airport every day.
Search flight deals

Frequently asked questions about flying from Knoxville to Detroit Metropolitan Wayne County Airport

  • How far is Knoxville McGhee Tyson to Detroit Metropolitan Wayne County by plane?

    A flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County will travel around 433.4 mi. By plane, this route typically takes 1h 44m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Knoxville to Detroit Metropolitan Wayne County Airport?

  • What is the most popular airline from Knoxville to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Knoxville to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Knoxville to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $299Free CancellationRating
7.8
8,605 reviews
Search Delta flights

  • Delta Flights From Knoxville to Detroit Metropolitan Wayne County Airport

    Delta operates around 19 flights from Knoxville to Detroit Metropolitan Wayne County Airport every week. The average price of these flights found in the last 72 hours has been $445, but momondo users have found Delta deals from Knoxville to Detroit Metropolitan Wayne County Airport from as low as $299 round-trip. Delta has been scored 7.8/10 in 8,605 reviews.

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Dearborn
Warren
Romulus
Troy
Southfield
Monroe
Livonia
Roseville
Novi
Port Clinton
Sterling Heights
Belleville
Port Huron
Dundee
Pontiac
Farmington Hills
Ypsilanti
Howell

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Detroit?

Finding the right flight to Detroit from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Detroit quick and easy, saving you time and money.

Can I find flights from Knoxville to Detroit with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Detroit flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Detroit?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Detroit.

I’m not ready to book a flight from Knoxville to Detroit right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Detroit from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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