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Cheap flights from Key West to Los Angeles from $280

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Key West to Los Angeles departing on 12/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Key West to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:05 pm - 6:31 pm
EYW
-
SNA
27h 26m2 stops
United Airlines Logo
7:55 am - 1:03 pm
SNA
-
EYW
26h 08m2 stops
$646United Airlines
Fri, Jan 9 - Sun, Jan 11
United Airlines Logo
6:05 pm - 6:31 pm
EYW
-
SNA
27h 26m2 stops
United Airlines Logo
2:16 pm - 3:17 pm
SNA
-
EYW
22h 01m1 stop
$661United Airlines
Fri, Jan 9 - Sun, Jan 11
United Airlines Logo
6:05 pm - 8:38 am
EYW
-
SNA
17h 33m2 stops
United Airlines Logo
2:16 pm - 3:17 pm
SNA
-
EYW
22h 01m1 stop
$696United Airlines
Fri, Jan 9 - Sun, Jan 11
United Airlines Logo
6:05 pm - 8:42 pm
EYW
-
SNA
29h 37m2 stops
United Airlines Logo
6:25 pm - 3:17 pm
SNA
-
EYW
17h 52m3 stops
$709United Airlines
Fri, Jan 9 - Sun, Jan 11
United Airlines Logo
6:05 pm - 6:31 pm
EYW
-
SNA
27h 26m2 stops
United Airlines Logo
6:25 pm - 3:17 pm
SNA
-
EYW
17h 52m3 stops
$722United Airlines
Fri, Jan 9 - Sun, Jan 11
United Airlines Logo
4:15 pm - 10:24 pm
EYW
-
SNA
9h 09m1 stop
United Airlines Logo
2:16 pm - 3:17 pm
SNA
-
EYW
22h 01m1 stop
$729United Airlines
Fri, Jan 9 - Sun, Jan 11

United Airlines flights from Key West to Santa Ana, California

Our best United Airlines deals on Key West to Santa Ana, California flight tickets
United Airlines
Jan 9
EYW6:05 pmKey West
27h 26m
2 stops
SNA6:31 pmSanta Ana J. Wayne/Orange Cnty
Jan 11
SNA7:55 amSanta Ana J. Wayne/Orange Cnty
26h 08m
2 stops
EYW1:03 pmKey West
$646
Find similar
United Airlines
Jan 9
EYW6:05 pmKey West
27h 26m
2 stops
SNA6:31 pmSanta Ana J. Wayne/Orange Cnty
Jan 11
SNA2:16 pmSanta Ana J. Wayne/Orange Cnty
22h 01m
1 stop
EYW3:17 pmKey West
$661
Find similar
United Airlines
Jan 9
EYW6:05 pmKey West
17h 33m
2 stops
SNA8:38 amSanta Ana J. Wayne/Orange Cnty
Jan 11
SNA2:16 pmSanta Ana J. Wayne/Orange Cnty
22h 01m
1 stop
EYW3:17 pmKey West
$696
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Key West to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Key West to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Fri 1/9

6:05 pm-6:31 pm

2 stops27h 26m

Santa Ana J. Wayne/Orange Cnty

Sun 1/11

7:55 am-1:03 pm

2 stops26h 08m

$646

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Fri 1/9

6:05 pm-6:31 pm

2 stops27h 26m

Santa Ana J. Wayne/Orange Cnty

Sun 1/11

2:16 pm-3:17 pm

1 stop22h 01m

$661

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Fri 1/9

6:05 pm-8:38 am

2 stops17h 33m

Santa Ana J. Wayne/Orange Cnty

Sun 1/11

2:16 pm-3:17 pm

1 stop22h 01m

$696

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Fri 1/9

6:05 pm-8:42 pm

2 stops29h 37m

Santa Ana J. Wayne/Orange Cnty

Sun 1/11

6:25 pm-3:17 pm

3 stops17h 52m

$709

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Fri 1/9

6:05 pm-6:31 pm

2 stops27h 26m

Santa Ana J. Wayne/Orange Cnty

Sun 1/11

6:25 pm-3:17 pm

3 stops17h 52m

$722

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Fri 1/9

4:15 pm-10:24 pm

1 stop9h 09m

Santa Ana J. Wayne/Orange Cnty

Sun 1/11

2:16 pm-3:17 pm

1 stop22h 01m

$729

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Tue 12/23

10:32 pm-10:16 am

3 stops38h 44m

$280

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Tue 12/23

10:59 am-10:16 am

2 stops26h 17m

$295

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Tue 12/23

12:20 pm-10:27 pm

2 stops13h 07m

$298

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Mon 12/22

2:30 pm-10:27 pm

2 stops10h 57m

$343

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Key West to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to Santa Ana, California?

In the afternoon is the cheapest time of day to fly from Key West to Santa Ana, California when you can find flight prices for as low as $511. Flying to Santa Ana, California in the afternoon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Santa Ana, California is at noon when prices are around $573.

Can stopping save me money on Key West to Santa Ana, California flights?

You could potentially save up to 37% on your flight if you consider stops on a Key West to Santa Ana, California flight.

When to book flights from Key West to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Key West to Santa Ana, California (EYW to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to Santa Ana, California

Fastest flight time

10h 28m

Direct flights

None
The fastest flight from Key West to Santa Ana, California takes 10h 28m
There are no direct flights from Key West to Santa Ana, California. There are no popular flight routes from Key West to Santa Ana, California.
Search flight deals

  • How far is Key West to Santa Ana J. Wayne/Orange Cnty by plane?

    A flight from Key West to Santa Ana J. Wayne/Orange Cnty will travel around 2252.7 mi. 10h 28m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents required for your trip to Santa Ana J. Wayne/Orange Cnty Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Ana J. Wayne/Orange Cnty Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Key West to Santa Ana, California?

Best airlines flying from Key West to Santa Ana, California

Compare and see reviews for airlines that fly from Key West to Santa Ana, California with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $338Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights
DeltaPriceFrom $373Free CancellationRating
7.9
8,008 reviews
Search Delta flights
United AirlinesPriceFrom $447Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Key West to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Key West to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Key West to Santa Ana with flexible booking policies on momondo?

Flights from Key West to Santa Ana with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Key West to Santa Ana?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Key West to Santa Ana.

I’m not ready to book a flight from Key West to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Key West to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

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