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Cheap flights from Key West to Los Angeles from $309

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Key West to Los Angeles departing on 11/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Key West to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
4:10 pm - 8:46 amEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
19h 36m2 stops Chicago O'Hare Intl San Francisco
United Airlines Logo
6:36 pm - 3:29 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
17h 53m2 stops San Francisco Chicago O'Hare Intl
$755United Airlines
Fri, Oct 30 - Tue, Nov 3
United Airlines Logo
2:51 pm - 9:44 amEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
21h 53m1 stop Newark
United Airlines Logo
6:30 pm - 3:29 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
17h 59m2 stops Denver Intl Chicago O'Hare Intl
$801United Airlines
Fri, Oct 30 - Tue, Nov 3
United Airlines Logo
2:50 pm - 3:59 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
28h 09m2 stops Newark Denver Intl
United Airlines Logo
6:30 pm - 3:29 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
17h 59m2 stops Denver Intl Chicago O'Hare Intl
$856United Airlines
Sat, Oct 31 - Tue, Nov 3
United Airlines Logo
2:50 pm - 3:59 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
28h 09m2 stops Newark Denver Intl
United Airlines Logo
6:36 pm - 3:29 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
17h 53m2 stops San Francisco Chicago O'Hare Intl
$857United Airlines
Sat, Oct 31 - Tue, Nov 3
United Airlines Logo
2:50 pm - 10:44 amEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
22h 54m1 stop Newark
United Airlines Logo
4:05 pm - 3:29 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
20h 24m2 stops Denver Intl Chicago O'Hare Intl
$861United Airlines
Sat, Oct 31 - Tue, Nov 3
United Airlines Logo
2:50 pm - 10:44 amEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
22h 54m1 stop Newark
United Airlines Logo
10:47 am - 3:29 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
25h 42m1 stop Chicago O'Hare Intl
$932United Airlines
Sat, Oct 31 - Tue, Nov 3
United Airlines Logo
2:50 pm - 10:40 amEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
22h 50m2 stops Newark Denver Intl
United Airlines Logo
8:46 am - 3:29 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
27h 43m3 stops Denver Intl Houston George Bush Intcntl Chicago O'Hare Intl
$938United Airlines
Sat, Oct 31 - Tue, Nov 3
United Airlines Logo
4:10 pm - 10:28 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 18m1 stop Chicago O'Hare Intl
United Airlines Logo
9:10 pm - 1:52 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
13h 42m1 stop Newark
$986United Airlines
Fri, Oct 30 - Tue, Nov 3
United Airlines Logo
4:10 pm - 10:28 pmEYW  Key West-SNA Santa Ana J. Wayne/Orange Cnty
9h 18m1 stop Chicago O'Hare Intl
United Airlines Logo
9:10 pm - 1:52 pmSNA  Santa Ana J. Wayne/Orange Cnty-EYW Key West
13h 42m1 stop Newark
$1,046United Airlines
Fri, Oct 30 - Tue, Nov 3

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United Airlines flights from Key West to Santa Ana, California

Our best United Airlines deals on Key West to Santa Ana, California flight tickets
United Airlines
Oct 30
EYW4:10 pmKey West
19h 36m
2 stops
SNA8:46 amSanta Ana J. Wayne/Orange Cnty
Nov 3
SNA6:36 pmSanta Ana J. Wayne/Orange Cnty
17h 53m
2 stops
EYW3:29 pmKey West
$755
United Airlines
Oct 30
EYW2:51 pmKey West
21h 53m
1 stop
SNA9:44 amSanta Ana J. Wayne/Orange Cnty
Nov 3
SNA6:30 pmSanta Ana J. Wayne/Orange Cnty
17h 59m
2 stops
EYW3:29 pmKey West
$801
United Airlines
Oct 31
EYW2:50 pmKey West
28h 09m
2 stops
SNA3:59 pmSanta Ana J. Wayne/Orange Cnty
Nov 3
SNA6:30 pmSanta Ana J. Wayne/Orange Cnty
17h 59m
2 stops
EYW3:29 pmKey West
$856

momondo Fare Finder

 
Customize your flight search to find flights from Key West to Santa Ana, California that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 9, 2026.
Use the filters below to find and compare flights from Key West to Santa Ana, California that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Key WestSanta Ana

EYW Key West - SNA Santa Ana J. Wayne/Orange Cnty

EYWSNA

Key West

Fri 10/30

4:10 pm-8:46 am

2 stops19h 36m

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

6:36 pm-3:29 pm

2 stops17h 53m

$755

Key WestSanta Ana

EYW Key West - SNA Santa Ana J. Wayne/Orange Cnty

EYWSNA

Key West

Fri 10/30

2:51 pm-9:44 am

1 stop21h 53m

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

6:30 pm-3:29 pm

2 stops17h 59m

$801

Key WestSanta Ana

EYW Key West - SNA Santa Ana J. Wayne/Orange Cnty

EYWSNA

Key West

Sat 10/31

2:50 pm-3:59 pm

2 stops28h 09m

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

6:30 pm-3:29 pm

2 stops17h 59m

$856

Key WestSanta Ana

EYW Key West - SNA Santa Ana J. Wayne/Orange Cnty

EYWSNA

Key West

Sat 10/31

2:50 pm-3:59 pm

2 stops28h 09m

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

6:36 pm-3:29 pm

2 stops17h 53m

$857

Key WestSanta Ana

EYW Key West - SNA Santa Ana J. Wayne/Orange Cnty

EYWSNA

Key West

Sat 10/31

2:50 pm-10:44 am

1 stop22h 54m

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

4:05 pm-3:29 pm

2 stops20h 24m

$861

Key WestSanta Ana

EYW Key West - SNA Santa Ana J. Wayne/Orange Cnty

EYWSNA

Key West

Sat 10/31

2:50 pm-10:44 am

1 stop22h 54m

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

10:47 am-3:29 pm

1 stop25h 42m

$932

Key WestSanta Ana

EYW Key West - SNA Santa Ana J. Wayne/Orange Cnty

EYWSNA

Key West

Sat 10/31

2:50 pm-10:40 am

2 stops22h 50m

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

8:46 am-3:29 pm

3 stops27h 43m

$938
Quickest round-trip

Key WestSanta Ana

EYW Key West - SNA Santa Ana J. Wayne/Orange Cnty

EYWSNA

Key West

Fri 10/30

4:10 pm-10:28 pm

1 stop9h 18m

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

9:10 pm-1:52 pm

1 stop13h 42m

$986

Key WestSanta Ana

EYW Key West - SNA Santa Ana J. Wayne/Orange Cnty

EYWSNA

Key West

Fri 10/30

4:10 pm-10:28 pm

1 stop9h 18m

Santa Ana J. Wayne/Orange Cnty

Tue 11/3

9:10 pm-1:52 pm

1 stop13h 42m

$1,046
Cheapest one-way

Key WestSanta Ana

EYW Key West - SNA Santa Ana J. Wayne/Orange Cnty

EYWSNA

Key West

Sun 11/22

3:06 pm-7:09 pm

2 stops31h 03m

$309

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Key West to Santa Ana, California

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Key West to Santa Ana, California flights?

You could potentially save up to 25% on your flight if you consider stops on a Key West to Santa Ana, California flight.

When to book flights from Key West to Santa Ana, California

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to Santa Ana, California according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Key West to Santa Ana, California (EYW to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to Santa Ana, California

Fastest flight time

25h 49m

Direct flights

None
The fastest flight from Key West to Santa Ana, California takes 25h 49m
There are no direct flights from Key West to Santa Ana, California. There are no popular flight routes from Key West to Santa Ana, California.
Search flight deals

Frequently asked questions about flying from Key West to Santa Ana, California

  • How far is Key West to Santa Ana J. Wayne/Orange Cnty by plane?

    A flight from Key West to Santa Ana J. Wayne/Orange Cnty will travel around 2252.7 mi. 25h 49m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How old do you have to be to fly from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents required for your trip to Santa Ana J. Wayne/Orange Cnty Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Ana J. Wayne/Orange Cnty Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
Tustin

Why use momondo?

Why should I use momondo to find a flight deal from Key West to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Key West to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Key West to Santa Ana with flexible booking policies on momondo?

Flights from Key West to Santa Ana with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Key West to Santa Ana?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Key West to Santa Ana.

I’m not ready to book a flight from Key West to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Key West to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

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