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Cheap flights from Key West to Los Angeles from $173

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Key West to Los Angeles departing on 11/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Key West to Los Angeles

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:51 pm - 10:13 pmEYW-SNA
9h 22m1 stop
American Airlines Logo
7:58 am - 6:30 pmSNA-EYW
7h 32m1 stop
$524American Airlines
Find Deal
Fri, Mar 6 - Tue, Mar 10
American Airlines Logo
1:23 pm - 8:24 pmEYW-SNA
10h 01m1 stop
American Airlines Logo
7:58 am - 11:59 pmSNA-EYW
13h 01m2 stops
$529American Airlines
Find Deal
Fri, Mar 6 - Tue, Mar 10
American Airlines Logo
12:10 pm - 7:28 pmEYW-SNA
10h 18m2 stops
American Airlines Logo
10:25 am - 11:59 pmSNA-EYW
10h 34m2 stops
$556American Airlines
Find Deal
Fri, Mar 6 - Tue, Mar 10
United Airlines Logo
4:00 pm - 10:13 pmEYW-SNA
9h 13m1 stop
United Airlines Logo
6:25 pm - 2:04 pmSNA-EYW
16h 39m2 stops
$559United Airlines
Find Deal
Wed, Nov 5 - Mon, Nov 10
United Airlines Logo
4:00 pm - 10:13 pmEYW-SNA
9h 13m1 stop
United Airlines Logo
6:45 am - 3:19 pmSNA-EYW
29h 34m1 stop
$573United Airlines
Find Deal
Wed, Nov 5 - Mon, Nov 10
Delta Logo
7:40 am - 6:19 pmEYW-SNA
13h 39m2 stops
Delta Logo
6:45 pm - 11:31 amSNA-EYW
13h 46m2 stops
$709Delta
Find Deal
Thu, Nov 6 - Mon, Nov 10
Delta Logo
7:40 am - 4:19 pmEYW-SNA
11h 39m2 stops
Delta Logo
7:00 am - 7:53 pmSNA-EYW
9h 53m2 stops
$3,648Delta
Find Deal
Wed, Nov 5 - Mon, Nov 10

American Airlines flights from Key West to Santa Ana

Our best American Airlines deals on Key West to Santa Ana flight tickets
American Airlines
Mar 6
EYW3:51 pmKey West
9h 22m
1 stop
SNA10:13 pmSanta Ana J. Wayne/Orange Cnty
Mar 10
SNA7:58 amSanta Ana J. Wayne/Orange Cnty
7h 32m
1 stop
EYW6:30 pmKey West
$524
Find similar
American Airlines
Mar 6
EYW1:23 pmKey West
10h 01m
1 stop
SNA8:24 pmSanta Ana J. Wayne/Orange Cnty
Mar 10
SNA7:58 amSanta Ana J. Wayne/Orange Cnty
13h 01m
2 stops
EYW11:59 pmKey West
$529
Find similar
American Airlines
Mar 6
EYW12:10 pmKey West
10h 18m
2 stops
SNA7:28 pmSanta Ana J. Wayne/Orange Cnty
Mar 10
SNA10:25 amSanta Ana J. Wayne/Orange Cnty
10h 34m
2 stops
EYW11:59 pmKey West
$556
Find similar

United Airlines flights from Key West to Santa Ana

Our best United Airlines deals on Key West to Santa Ana flight tickets
United Airlines
Nov 5
EYW4:00 pmKey West
9h 13m
1 stop
SNA10:13 pmSanta Ana J. Wayne/Orange Cnty
Nov 10
SNA6:25 pmSanta Ana J. Wayne/Orange Cnty
16h 39m
2 stops
EYW2:04 pmKey West
$559
Find similar
United Airlines
Nov 5
EYW4:00 pmKey West
9h 13m
1 stop
SNA10:13 pmSanta Ana J. Wayne/Orange Cnty
Nov 10
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
29h 34m
1 stop
EYW3:19 pmKey West
$573
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Key West to Santa Ana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 20, 2025.
Use the filters below to find and compare flights from Key West to Santa Ana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Fri 3/6

3:51 pm-10:13 pm

1 stop9h 22m

Santa Ana J. Wayne/Orange Cnty

Tue 3/10

7:58 am-6:30 pm

1 stop7h 32m

$524

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Fri 3/6

1:23 pm-8:24 pm

1 stop10h 01m

Santa Ana J. Wayne/Orange Cnty

Tue 3/10

7:58 am-11:59 pm

2 stops13h 01m

$529

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Fri 3/6

12:10 pm-7:28 pm

2 stops10h 18m

Santa Ana J. Wayne/Orange Cnty

Tue 3/10

10:25 am-11:59 pm

2 stops10h 34m

$556

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Wed 11/5

4:00 pm-10:13 pm

1 stop9h 13m

Santa Ana J. Wayne/Orange Cnty

Mon 11/10

6:25 pm-2:04 pm

2 stops16h 39m

$559

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Wed 11/5

4:00 pm-10:13 pm

1 stop9h 13m

Santa Ana J. Wayne/Orange Cnty

Mon 11/10

6:45 am-3:19 pm

1 stop29h 34m

$573

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Thu 11/6

7:40 am-6:19 pm

2 stops13h 39m

Santa Ana J. Wayne/Orange Cnty

Mon 11/10

6:45 pm-11:31 am

2 stops13h 46m

$709

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Wed 11/5

7:40 am-4:19 pm

2 stops11h 39m

Santa Ana J. Wayne/Orange Cnty

Mon 11/10

7:00 am-7:53 pm

2 stops9h 53m

$3,648

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Sun 11/16

12:15 pm-1:30 pm

3 stops52h 15m

$173

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Sun 11/16

12:15 pm-9:01 pm

2 stops35h 46m

$182

Key WestSanta Ana

EYW - SNA

EYWSNA

Key West

Mon 12/1

8:55 am-4:51 pm

2 stops34h 56m

$186

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Los Angeles from

How to get the cheapest flight ticket from Key West to Santa Ana

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest time of day to depart on your flight to Santa Ana?

Our data shows that the cheapest Key West to Santa Ana flights are usually those with departure times in the afternoon. Our users have found flights to Santa Ana in the afternoon for as low as $511. Try not to purchase tickets at noon because they tend to be around $573. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Key West to Santa Ana flights?

You could potentially save up to 32% on your flight if you consider stops on a Key West to Santa Ana flight.

When to book flights from Key West to Santa Ana

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to Santa Ana according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Key West to Santa Ana (EYW to SNA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to Santa Ana

Direct flights

None
There are no direct flights from Key West to Santa Ana. There are no popular flight routes from Key West to Santa Ana.
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  • How far is Key West to Santa Ana J. Wayne/Orange Cnty by plane?

    A flight from Key West to Santa Ana J. Wayne/Orange Cnty will travel around 2252.7 mi. 9h 13m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    Prices for flights from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport were last updated today.

  • How many operators does momondo search for flights from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport?

  • How old do you have to be to fly from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to Santa Ana J. Wayne/Orange Cnty Airport.

  • What documentation or ID do you need to fly to Santa Ana J. Wayne/Orange Cnty Airport?

    The travel and health documents required for your trip to Santa Ana J. Wayne/Orange Cnty Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Ana J. Wayne/Orange Cnty Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Key West to Santa Ana?

Best airlines flying from Key West to Santa Ana

Compare and see reviews for airlines that fly from Key West to Santa Ana with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $344Free CancellationRating
7.2
11,024 reviews
Search American Airlines flights
DeltaPriceFrom $373Free CancellationRating
7.9
7,978 reviews
Search Delta flights
United AirlinesPriceFrom $447Free CancellationRating
7.4
8,991 reviews
Search United Airlines flights

Traveling to a place near Los Angeles?

Book flights to Los Angeles if you plan to visit one of these locations
Anaheim
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Why use momondo?

Why should I use momondo to find a flight deal from Key West to Santa Ana?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Key West to Santa Ana. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Key West to Santa Ana with flexible booking policies on momondo?

Flights from Key West to Santa Ana with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Key West to Santa Ana?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Key West to Santa Ana.

I’m not ready to book a flight from Key West to Santa Ana right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Key West to Santa Ana now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santa Ana and let you know when they change.

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