Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Key West to San Francisco from $232

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Key West to San Francisco departing on 5/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Key West to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:58 pm - 11:01 pm
EYW
-
SFO
10h 03m
1 stop
American Airlines Logo
5:00 am - 6:49 pm
SFO
-
EYW
10h 49m
1 stop
$410American Airlines
Wed, May 20 - Sun, May 24
American Airlines Logo
3:58 pm - 11:01 pm
EYW
-
SFO
10h 03m
1 stop
American Airlines Logo
8:13 pm - 10:56 am
SFO
-
EYW
11h 43m
2 stops
$415American Airlines
Wed, May 20 - Sun, May 24
American Airlines Logo
11:28 am - 7:21 pm
EYW
-
SFO
10h 53m
2 stops
American Airlines Logo
11:49 pm - 12:16 pm
SFO
-
EYW
9h 27m
1 stop
$434American Airlines
Thu, May 21 - Mon, May 25
American Airlines Logo
11:28 am - 7:21 pm
EYW
-
SFO
10h 53m
2 stops
American Airlines Logo
8:13 pm - 10:56 am
SFO
-
EYW
11h 43m
2 stops
$439American Airlines
Thu, May 21 - Mon, May 25
American Airlines Logo
3:58 pm - 11:51 pm
EYW
-
SFO
10h 53m
2 stops
American Airlines Logo
8:13 pm - 10:56 am
SFO
-
EYW
11h 43m
2 stops
$481American Airlines
Wed, May 20 - Sun, May 24
American Airlines Logo
8:03 am - 2:37 pm
EYW
-
SFO
9h 34m
1 stop
American Airlines Logo
5:00 am - 6:49 pm
SFO
-
EYW
10h 49m
1 stop
$547American Airlines
Thu, May 21 - Mon, May 25
Delta Logo
7:30 am - 2:56 pm
EYW
-
SFO
10h 26m
1 stop
Delta Logo
8:25 am - 7:49 pm
SFO
-
EYW
8h 24m
1 stop
$648Delta
Sat, May 23 - Wed, May 27
Delta Logo
11:48 am - 7:05 pm
EYW
-
SFO
10h 17m
1 stop
Delta Logo
7:50 am - 7:53 pm
SFO
-
EYW
9h 03m
1 stop
$799Delta
Sat, Jun 6 - Fri, Jun 12
American Airlines Logo
11:31 am - 7:21 pm
EYW
-
SFO
10h 50m
2 stops
American Airlines Logo
7:45 am - 7:10 pm
SFO
-
EYW
8h 25m
1 stop
$800American Airlines
Sat, May 23 - Wed, May 27
American Airlines Logo
11:31 am - 7:10 pm
EYW
-
SFO
10h 39m
2 stops
American Airlines Logo
5:23 am - 6:49 pm
SFO
-
EYW
10h 26m
2 stops
$805American Airlines
Sat, May 23 - Wed, May 27

American Airlines flights from Key West to San Francisco

Our best American Airlines deals on Key West to San Francisco flight tickets
American Airlines
May 20
EYW3:58 pmKey West
10h 03m
1 stop
SFO11:01 pmSan Francisco
May 24
SFO5:00 amSan Francisco
10h 49m
1 stop
EYW6:49 pmKey West
$410
American Airlines
May 20
EYW3:58 pmKey West
10h 03m
1 stop
SFO11:01 pmSan Francisco
May 24
SFO8:13 pmSan Francisco
11h 43m
2 stops
EYW10:56 amKey West
$415
American Airlines
May 21
EYW11:28 amKey West
10h 53m
2 stops
SFO7:21 pmSan Francisco
May 25
SFO11:49 pmSan Francisco
9h 27m
1 stop
EYW12:16 pmKey West
$434

Breeze Airways flights from Key West to San Francisco

Our best Breeze Airways deals on Key West to San Francisco flight tickets
Breeze Airways
May 21
EYW12:05 pmKey West
50h 32m
3 stops
SFO11:37 amSan Francisco
May 25
SFO12:18 pmSan Francisco
43h 48m
3 stops
EYW11:06 amKey West
$962
Breeze Airways
May 21
EYW11:04 amKey West
51h 33m
2 stops
SFO11:37 amSan Francisco
May 25
SFO12:18 pmSan Francisco
43h 48m
3 stops
EYW11:06 amKey West
$1,106
Breeze Airways
May 20
EYW11:46 amKey West
50h 47m
3 stops
SFO11:33 amSan Francisco
May 24
SFO12:47 pmSan Francisco
44h 47m
3 stops
EYW12:34 pmKey West
$1,169

momondo Fare Finder

 
Customize your flight search to find flights from Key West to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Key West to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 5/20

3:58 pm-11:01 pm

1 stop10h 03m

San Francisco

Sun 5/24

5:00 am-6:49 pm

1 stop10h 49m

$410

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 5/20

3:58 pm-11:01 pm

1 stop10h 03m

San Francisco

Sun 5/24

8:13 pm-10:56 am

2 stops11h 43m

$415

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Thu 5/21

11:28 am-7:21 pm

2 stops10h 53m

San Francisco

Mon 5/25

11:49 pm-12:16 pm

1 stop9h 27m

$434

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Thu 5/21

11:28 am-7:21 pm

2 stops10h 53m

San Francisco

Mon 5/25

8:13 pm-10:56 am

2 stops11h 43m

$439

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 5/20

3:58 pm-11:51 pm

2 stops10h 53m

San Francisco

Sun 5/24

8:13 pm-10:56 am

2 stops11h 43m

$481

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Thu 5/21

8:03 am-2:37 pm

1 stop9h 34m

San Francisco

Mon 5/25

5:00 am-6:49 pm

1 stop10h 49m

$547
Quickest round-trip

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Sat 5/23

7:30 am-2:56 pm

1 stop10h 26m

San Francisco

Wed 5/27

8:25 am-7:49 pm

1 stop8h 24m

$648

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Sat 6/6

11:48 am-7:05 pm

1 stop10h 17m

San Francisco

Fri 6/12

7:50 am-7:53 pm

1 stop9h 03m

$799

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Sat 5/23

11:31 am-7:21 pm

2 stops10h 50m

San Francisco

Wed 5/27

7:45 am-7:10 pm

1 stop8h 25m

$800

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Sat 5/23

11:31 am-7:10 pm

2 stops10h 39m

San Francisco

Wed 5/27

5:23 am-6:49 pm

2 stops10h 26m

$805

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to San Francisco from

How to get the cheapest flight ticket from Key West to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

How have Key West to San Francisco flight prices changed over time?

As of May 2026, prices for Key West to San Francisco flights are approximately 0% more expensive when compared to flights at the same time last year.

When to book flights from Key West to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Key West to San Francisco (EYW to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to San Francisco

Fastest flight time

9h 27m

Direct flights

None
The fastest flight from Key West to San Francisco takes 9h 27m
There are no direct flights from Key West to San Francisco. There are no popular flight routes from Key West to San Francisco.
Search flight deals

Frequently asked questions about flying from Key West to San Francisco

  • How far is Key West to San Francisco by plane?

    A flight from Key West to San Francisco will travel around 2542.9 mi. 9h 27m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Key West Airport to San Francisco Airport?

    Prices for flights from Key West Airport to San Francisco Airport were last updated today.

  • How many operators does momondo search for flights from Key West Airport to San Francisco Airport?

  • How old do you have to be to fly from Key West Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Key West to San Francisco?

Best airlines flying from Key West to San Francisco

Compare and see reviews for airlines that fly from Key West to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $348Free CancellationRating
7.1
11,669 reviews
Search American Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Walnut Creek
Roseville
Berkeley
Hayward
Santa Clara
Fremont
Vallejo
Big Sur
Calistoga
Sunnyvale
South San Francisco
Salinas
Daly City
Half Moon Bay
Pacific Grove

Why use momondo?

Why should I use momondo to find a flight deal from Key West to San Francisco?

Finding the right flight to San Francisco from Key West is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Key West to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Key West which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Key West to San Francisco?

momondo helps you find the best flight between Key West and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Key West to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Key West are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 6/9
Tue 6/16
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States