What is the cheapest airline that flies from Key West to San Francisco?

Delta and American Airlines are the most popular carriers operating from Key West to San Francisco

When did momondo last update prices for flights from Key West Airport to San Francisco Airport?

Prices for flights from Key West Airport to San Francisco Airport were last updated today.

How old do you have to be to fly from Key West Airport to San Francisco Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to San Francisco Airport.

What documentation or ID do you need to fly to San Francisco Airport?

The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$185 Cheap Flights from Key West to San Francisco (EYW-SFO) in 2025

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Find the cheapest flights from Key West to San Francisco (EYW-SFO)

Round-trip

One-way

Cheap round-trip flights

2:00 pm - 8:28 pmEYW-SFO

9h 28m1 stop

6:15 am - 5:15 pmSFO-EYW

8h 00m1 stop

$269Delta

Find Deal

Wed, Sep 17 - Wed, Sep 24

3:45 pm - 9:52 pmEYW-SFO

9h 07m1 stop

5:45 am - 6:59 pmSFO-EYW

10h 14m2 stops

$274American Airlines

Find Deal

Wed, Sep 17 - Wed, Sep 24

11:25 am - 9:52 pmEYW-SFO

13h 27m2 stops

5:45 am - 6:59 pmSFO-EYW

10h 14m2 stops

$279American Airlines

Find Deal

Wed, Sep 17 - Wed, Sep 24

2:00 pm - 8:28 pmEYW-SFO

9h 28m1 stop

6:15 am - 5:15 pmSFO-EYW

8h 00m1 stop

$309Delta

Find Deal

Wed, Sep 17 - Wed, Sep 24

3:45 pm - 9:52 pmEYW-SFO

9h 07m1 stop

5:45 am - 6:59 pmSFO-EYW

10h 14m2 stops

$364American Airlines

Find Deal

Wed, Sep 17 - Wed, Sep 24

11:52 am - 6:52 pmEYW-SFO

10h 00m1 stop

9:38 pm - 10:55 amSFO-EYW

10h 17m1 stop

$369Delta

Find Deal

Wed, Sep 10 - Sun, Sep 14

11:25 am - 9:52 pmEYW-SFO

13h 27m2 stops

10:50 pm - 11:13 amSFO-EYW

9h 23m1 stop

$374American Airlines

Find Deal

Wed, Sep 10 - Sun, Sep 14

11:25 am - 9:05 pmEYW-SFO

12h 40m2 stops

6:51 pm - 11:13 amSFO-EYW

13h 22m2 stops

$379American Airlines

Find Deal

Wed, Sep 10 - Sun, Sep 14

3:45 pm - 9:52 pmEYW-SFO

9h 07m1 stop

12:47 am - 5:46 pmSFO-EYW

13h 59m2 stops

$800American Airlines

Find Deal

Wed, Sep 17 - Tue, Sep 23

9:47 am - 12:05 pmEYW-SFO

29h 18m3 stops

12:39 pm - 8:07 amSFO-EYW

40h 28m2 stops

$1,010Breeze Airways

Find Deal

Wed, Sep 17 - Wed, Sep 24

Delta flights from Key West to San Francisco

Our best Delta deals on Key West to San Francisco flight tickets

Delta

Sep 17

EYW2:00 pmKey West

9h 28m

1 stop

SFO8:28 pmSan Francisco

Sep 24

SFO6:15 amSan Francisco

8h 00m

1 stop

EYW5:15 pmKey West

$269

Find similar

Delta

Sep 17

EYW2:00 pmKey West

9h 28m

1 stop

SFO8:28 pmSan Francisco

Sep 24

SFO6:15 amSan Francisco

8h 00m

1 stop

EYW5:15 pmKey West

$309

Find similar

Delta

Sep 10

EYW11:52 amKey West

10h 00m

1 stop

SFO6:52 pmSan Francisco

Sep 14

SFO9:38 pmSan Francisco

10h 17m

1 stop

EYW10:55 amKey West

$369

Find similar

American Airlines flights from Key West to San Francisco

Our best American Airlines deals on Key West to San Francisco flight tickets

American Airlines

Sep 17

EYW3:45 pmKey West

9h 07m

1 stop

SFO9:52 pmSan Francisco

Sep 24

SFO5:45 amSan Francisco

10h 14m

2 stops

EYW6:59 pmKey West

$274

Find similar

American Airlines

Sep 17

EYW11:25 amKey West

13h 27m

2 stops

SFO9:52 pmSan Francisco

Sep 24

SFO5:45 amSan Francisco

10h 14m

2 stops

EYW6:59 pmKey West

$279

Find similar

American Airlines

Sep 17

EYW3:45 pmKey West

9h 07m

1 stop

SFO9:52 pmSan Francisco

Sep 24

SFO5:45 amSan Francisco

10h 14m

2 stops

EYW6:59 pmKey West

$364

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 9/17

2:00 pm-8:28 pm

1 stop9h 28m

San Francisco

Wed 9/24

6:15 am-5:15 pm

1 stop8h 00m

$269

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 9/17

3:45 pm-9:52 pm

1 stop9h 07m

San Francisco

Wed 9/24

5:45 am-6:59 pm

2 stops10h 14m

$274

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 9/17

11:25 am-9:52 pm

2 stops13h 27m

San Francisco

Wed 9/24

5:45 am-6:59 pm

2 stops10h 14m

$279

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 9/17

2:00 pm-8:28 pm

1 stop9h 28m

San Francisco

Wed 9/24

6:15 am-5:15 pm

1 stop8h 00m

$309

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 9/17

3:45 pm-9:52 pm

1 stop9h 07m

San Francisco

Wed 9/24

5:45 am-6:59 pm

2 stops10h 14m

$364

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 9/10

11:52 am-6:52 pm

1 stop10h 00m

San Francisco

Sun 9/14

9:38 pm-10:55 am

1 stop10h 17m

$369

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 9/10

11:25 am-9:52 pm

2 stops13h 27m

San Francisco

Sun 9/14

10:50 pm-11:13 am

1 stop9h 23m

$374

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 9/10

11:25 am-9:05 pm

2 stops12h 40m

San Francisco

Sun 9/14

6:51 pm-11:13 am

2 stops13h 22m

$379

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 9/17

3:45 pm-9:52 pm

1 stop9h 07m

San Francisco

Tue 9/23

12:47 am-5:46 pm

2 stops13h 59m

$800

Key WestSan Francisco

EYW - SFO

EYWSFO

Key West

Wed 9/17

9:47 am-12:05 pm

3 stops29h 18m

San Francisco

Wed 9/24

12:39 pm-8:07 am

2 stops40h 28m

$1,010

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Key West to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Key West to San Francisco is on a Saturday when prices can be found for as low as $394. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $617.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Key West to San Francisco flights are usually those with departure times at noon. Our users have found flights to San Francisco at noon for as low as $430. Flights in the afternoon are often more expensive with an average ticket price of $476.

How have Key West to San Francisco flight prices changed over time?

As of August 2025, prices for Key West to San Francisco flights are approximately 25% cheaper when compared to flights at the same time last year.

When to book flights from Key West to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to San Francisco according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Key West to San Francisco (EYW to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to San Francisco

Direct flights	None

There are no direct flights from Key West to San Francisco. There are no popular flight routes from Key West to San Francisco.

Search flight deals

How far is Key West to San Francisco by plane?
A flight from Key West to San Francisco will travel around 2543.6 mi. 9h 07m is a normal flight duration for this route.
When did momondo last update prices for flights from Key West Airport to San Francisco Airport?
Prices for flights from Key West Airport to San Francisco Airport were last updated today.
How old do you have to be to fly from Key West Airport to San Francisco Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to San Francisco Airport.
What documentation or ID do you need to fly to San Francisco Airport?
The travel and health documents required for your trip to San Francisco Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at San Francisco Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

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Modesto

Sonoma

Calistoga

Hayward

Bodega Bay

Roseville

Santa Clara

Big Sur

Daly City

Fremont

Berkeley

Walnut Creek

Half Moon Bay

South San Francisco

Vallejo

Redwood City

Pacific Grove

Salinas

Why use momondo?

Why should I use momondo to find a flight deal from Key West to San Francisco?

Finding the right flight to San Francisco from Key West is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to San Francisco quick and easy, saving you time and money.

Can I find flights from Key West to San Francisco with flexible booking policies on momondo?

momondo does allow users to show only those flights to San Francisco from Key West which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Key West to San Francisco?

momondo helps you find the best flight between Key West and San Francisco by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Key West to San Francisco right now. Can momondo alert me if prices change?

Price alerts on flights to San Francisco from Key West are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Cheap flights from Key West to San Francisco from $185

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Key West to San Francisco departing on 9/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Key West to San Francisco (EYW-SFO)

Cheap round-trip flights

Cheap one-way flights

Delta flights from Key West to San Francisco

Our best Delta deals on Key West to San Francisco flight tickets

American Airlines flights from Key West to San Francisco

Our best American Airlines deals on Key West to San Francisco flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Key West to San Francisco that are best for you.

See travel insights to San Francisco from

How to get the cheapest flight ticket from Key West to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Key West to San Francisco is on a Saturday when prices can be found for as low as $394. The most expensive day to fly to San Francisco is Sunday, with ticket prices averaging around $617.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Key West to San Francisco flights are usually those with departure times at noon. Our users have found flights to San Francisco at noon for as low as $430. Flights in the afternoon are often more expensive with an average ticket price of $476.

How have Key West to San Francisco flight prices changed over time?

As of August 2025, prices for Key West to San Francisco flights are approximately 25% cheaper when compared to flights at the same time last year.

What is the cheapest airline that flies from Key West to San Francisco?

Delta and American Airlines are the most popular carriers operating from Key West to San Francisco

When to book flights from Key West to San Francisco

Cheap Key West to San Francisco (EYW to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to San Francisco

Direct flights

How far is Key West to San Francisco by plane?

When did momondo last update prices for flights from Key West Airport to San Francisco Airport?

How old do you have to be to fly from Key West Airport to San Francisco Airport?

What documentation or ID do you need to fly to San Francisco Airport?

Traveling to a place near San Francisco?

Why use momondo?

Why should I use momondo to find a flight deal from Key West to San Francisco?

Can I find flights from Key West to San Francisco with flexible booking policies on momondo?

How can momondo help me find flights from Key West to San Francisco?

I’m not ready to book a flight from Key West to San Francisco right now. Can momondo alert me if prices change?

An easier way to manage your San Francisco trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing California