Cheap flights from Italy to San Francisco from $337

If you aren’t able to travel to San Francisco during the month of November, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $643.

The cheapest day to depart from Italy to San Francisco is on a Friday when prices can be found for as low as $652. The most expensive day to fly to San Francisco is Saturday, with ticket prices averaging around $935.

Our data shows that the cheapest Italy to San Francisco flights are usually those with departure times in the morning. Our users have found flights to San Francisco in the morning for as low as $736. Flights in the afternoon are often more expensive with an average ticket price of $823.

Fly from Rome Fiumicino to San Francisco for the best Italy - San Francisco flight prices

You are more likely to see cheaper flights to San Francisco from Italy when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $771 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Italy for as low as $562 on momondo.

There are 3 cabin classes available to choose from on Italy to San Francisco flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Finnair, Iberia, and American Airlines are the most popular carriers operating from Italy to San Francisco

United Airlines, ITA Airways and Lufthansa are the top three most popular airlines that fly to San Francisco from Italy according to our data. United Airlines is the first choice among our users, with 35% of people opting to fly with this airline when traveling to San Francisco. Keep in mind that there are 4 different airlines that fly to San Francisco on a routine basis, so you have a few additional options to choose from.

Historically, on average around 27% of flights between Italy and San Francisco have experienced a delay on any given week. The average delay length over the past 12 months has been 139 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

Sunday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

According to our data, United Airlines have had the least number of delays on this route over the last 12 months; with about 23% of their flights experiencing any sort of delay.

6 flights are operational weekly from Italy to San Francisco as of November 2026. The most popular departure day for this route is Tue, with 33% of flights per week taking off on this day.

Flight times from Italy to San Francisco vary, but if you’re flying out of Rome and flying into San Francisco (one of the most popular routes), then the duration is 12h 45m on average. Another popular route from Italy to San Francisco is flying from Venice to San Francisco, which will take roughly 14h 20m. Keep in mind that layovers or delays could extend your travel time.