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Cheap flights from Guayaquil to San Francisco from $231

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Guayaquil to San Francisco departing on 12/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Guayaquil to San Francisco

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
4:30 pm - 10:35 amGYE-SFO
21h 05m1 stop
Delta Logo
2:25 pm - 7:20 amSFO-GYE
13h 55m1 stop
$445Delta
Find Deal
Fri, Dec 12 - Wed, Jan 21
JetBlue Logo
4:31 pm - 9:18 amGYE-SFO
19h 47m1 stop
JetBlue Logo
8:45 pm - 3:20 pmSFO-GYE
15h 35m2 stops
$490JetBlue
Find Deal
Fri, Dec 12 - Wed, Jan 21
Multiple Airlines Logo
4:00 pm - 10:44 amGYE-SFO
20h 44m1 stop
Multiple Airlines Logo
11:11 pm - 7:20 amSFO-GYE
30h 09m1 stop
$521Multiple Airlines
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Mon, May 4 - Sat, May 16
Avianca Logo
4:40 am - 9:50 pmGYE-SFO
20h 10m2 stops
Avianca Logo
1:35 am - 11:35 pmSFO-GYE
19h 00m2 stops
$531Avianca
Find Deal
Wed, Nov 19 - Tue, Dec 2
Avianca Logo
4:40 am - 9:50 pmGYE-SFO
20h 10m2 stops
Avianca Logo
1:35 am - 11:35 pmSFO-GYE
19h 00m2 stops
$536Avianca
Find Deal
Wed, Nov 19 - Tue, Dec 2
Copa Airlines Logo
4:32 am - 11:17 pmGYE-SFO
21h 45m1 stop
Copa Airlines Logo
12:42 am - 5:35 pmSFO-GYE
13h 53m1 stop
$549Copa Airlines
Find Deal
Thu, Dec 11 - Tue, Jan 20
United Airlines Logo
8:34 am - 7:49 amGYE-SFO
26h 15m2 stops
United Airlines Logo
12:43 am - 11:42 pmSFO-GYE
19h 59m2 stops
$555United Airlines
Find Deal
Sat, Feb 7 - Fri, Feb 27
Multiple Airlines Logo
4:00 pm - 1:14 pmGYE-SFO
23h 14m1 stop
Multiple Airlines Logo
2:20 pm - 8:35 amSFO-GYE
16h 15m2 stops
$586Multiple Airlines
Find Deal
Mon, May 4 - Sat, May 16
United Airlines Logo
12:21 pm - 8:29 pmGYE-SFO
11h 08m1 stop
United Airlines Logo
4:10 pm - 8:43 pmSFO-GYE
25h 33m2 stops
$602United Airlines
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Thu, Nov 20 - Wed, Dec 3
Copa Airlines Logo
8:34 am - 11:20 pmGYE-SFO
17h 46m1 stop
Copa Airlines Logo
12:42 am - 11:55 pmSFO-GYE
20h 13m1 stop
$621Copa Airlines
Find Deal
Sat, Feb 7 - Fri, Feb 27

American Airlines flights from Guayaquil to San Francisco

Our best American Airlines deals on Guayaquil to San Francisco flight tickets
American Airlines
Dec 12
GYE6:10 amGuayaquil Jose Joaquin de Olmedo
19h 49m
1 stop
SFO10:59 pmSan Francisco
Jan 20
SFO12:17 amSan Francisco
20h 05m
2 stops
GYE11:22 pmGuayaquil Jose Joaquin de Olmedo
$568
Find similar
American Airlines
Dec 21
GYE6:08 amGuayaquil Jose Joaquin de Olmedo
20h 51m
1 stop
SFO11:59 pmSan Francisco
Jan 6
SFO1:15 pmSan Francisco
31h 07m
1 stop
GYE11:22 pmGuayaquil Jose Joaquin de Olmedo
$571
Find similar
American Airlines
Dec 21
GYE6:08 amGuayaquil Jose Joaquin de Olmedo
20h 51m
1 stop
SFO11:59 pmSan Francisco
Jan 6
SFO10:59 pmSan Francisco
21h 23m
1 stop
GYE11:22 pmGuayaquil Jose Joaquin de Olmedo
$574
Find similar

Copa Airlines flights from Guayaquil to San Francisco

Our best Copa Airlines deals on Guayaquil to San Francisco flight tickets
Copa Airlines
Dec 11
GYE4:32 amGuayaquil Jose Joaquin de Olmedo
21h 45m
1 stop
SFO11:17 pmSan Francisco
Jan 20
SFO12:42 amSan Francisco
13h 53m
1 stop
GYE5:35 pmGuayaquil Jose Joaquin de Olmedo
$549
Find similar
Copa Airlines
Feb 7
GYE8:34 amGuayaquil Jose Joaquin de Olmedo
17h 46m
1 stop
SFO11:20 pmSan Francisco
Feb 27
SFO12:42 amSan Francisco
20h 13m
1 stop
GYE11:55 pmGuayaquil Jose Joaquin de Olmedo
$621
Find similar
Copa Airlines
Feb 1
GYE12:20 pmGuayaquil Jose Joaquin de Olmedo
14h 00m
1 stop
SFO11:20 pmSan Francisco
Feb 17
SFO12:42 amSan Francisco
9h 52m
1 stop
GYE1:34 pmGuayaquil Jose Joaquin de Olmedo
$648
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momondo Fare Finder

 
Customize your flight search to find flights from Guayaquil to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Guayaquil to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 12/12

4:30 pm-10:35 am

1 stop21h 05m

San Francisco

Wed 1/21

2:25 pm-7:20 am

1 stop13h 55m

$445

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 12/12

4:31 pm-9:18 am

1 stop19h 47m

San Francisco

Wed 1/21

8:45 pm-3:20 pm

2 stops15h 35m

$490

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Mon 5/4

4:00 pm-10:44 am

1 stop20h 44m

San Francisco

Sat 5/16

11:11 pm-7:20 am

1 stop30h 09m

$521

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Wed 11/19

4:40 am-9:50 pm

2 stops20h 10m

San Francisco

Tue 12/2

1:35 am-11:35 pm

2 stops19h 00m

$531

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Wed 11/19

4:40 am-9:50 pm

2 stops20h 10m

San Francisco

Tue 12/2

1:35 am-11:35 pm

2 stops19h 00m

$536

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Thu 12/11

4:32 am-11:17 pm

1 stop21h 45m

San Francisco

Tue 1/20

12:42 am-5:35 pm

1 stop13h 53m

$549

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

8:34 am-7:49 am

2 stops26h 15m

San Francisco

Fri 2/27

12:43 am-11:42 pm

2 stops19h 59m

$555

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Mon 5/4

4:00 pm-1:14 pm

1 stop23h 14m

San Francisco

Sat 5/16

2:20 pm-8:35 am

2 stops16h 15m

$586

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Thu 11/20

12:21 pm-8:29 pm

1 stop11h 08m

San Francisco

Wed 12/3

4:10 pm-8:43 pm

2 stops25h 33m

$602

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

8:34 am-11:20 pm

1 stop17h 46m

San Francisco

Fri 2/27

12:42 am-11:55 pm

1 stop20h 13m

$621

Flights are sorted by cheapest round-trip flights first.

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See travel insights to San Francisco from

How to get the cheapest flight ticket from Guayaquil to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Guayaquil and San Francisco?

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of June, then flying in May is also cheap. Prices for this month can be found on momondo for an average of $547.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Guayaquil to San Francisco is on a Monday when prices can be found for as low as $358. The most expensive day to fly to San Francisco is Friday, with ticket prices averaging around $670.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Guayaquil to San Francisco flights are usually those with departure times at noon. Our users have found flights to San Francisco at noon for as low as $538. Flights in the morning are often more expensive with an average ticket price of $596.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Guayaquil when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $594 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Guayaquil for as low as $325 on momondo.

How have Guayaquil to San Francisco flight prices changed over time?

As of November 2025, prices for Guayaquil to San Francisco flights are approximately 13% more expensive when compared to flights at the same time last year.

When to book flights from Guayaquil to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Guayaquil to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Guayaquil to San Francisco (GYE to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Guayaquil to San Francisco

Direct flights

None
There are no direct flights from Guayaquil to San Francisco. There are no popular flight routes from Guayaquil to San Francisco.
Search flight deals

  • How far is Guayaquil Jose Joaquin de Olmedo to San Francisco by plane?

    A flight from Guayaquil Jose Joaquin de Olmedo to San Francisco will travel around 3869.7 mi. 11h 08m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to San Francisco Airport?

    Prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to San Francisco Airport are updated daily.

  • How many operators does momondo search for flights from Guayaquil Jose Joaquin de Olmedo Airport to San Francisco Airport?

  • How old do you have to be to fly from Guayaquil Jose Joaquin de Olmedo Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Guayaquil Jose Joaquin de Olmedo Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Guayaquil to San Francisco?

Best airlines flying from Guayaquil to San Francisco

Compare and see reviews for airlines that fly from Guayaquil to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $295Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $301Free CancellationRating
7.4
9,003 reviews
Search United Airlines flights
AviancaPriceFrom $398Free CancellationRating
6.6
2,469 reviews
Search Avianca flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Bodega Bay
Roseville
Calistoga
Hayward
Big Sur
Santa Clara
Daly City
Fremont
Berkeley
Vallejo
Walnut Creek
Half Moon Bay
Salinas
Livermore
Turlock
South San Francisco

Why use momondo?

Why should I use momondo to find a flight deal from Guayaquil to San Francisco?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Francisco from Guayaquil.

Can I find flights from Guayaquil to San Francisco with flexible booking policies on momondo?

All flight searches from Guayaquil to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Guayaquil to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Guayaquil.

I’m not ready to book a flight from Guayaquil to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Guayaquil to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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