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Cheap flights from Guayaquil to San Francisco from $410

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Guayaquil to San Francisco departing on 2/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Guayaquil to San Francisco

Cheap round-trip flights

JetBlue Logo
2:40 pm - 11:27 amGYE-SFO
22h 47m1 stop
JetBlue Logo
10:35 am - 1:30 pmSFO-GYE
24h 55m1 stop
$425JetBlue
Find Deal
Fri, Oct 17 - Fri, Oct 24
JetBlue Logo
2:40 pm - 11:27 amGYE-SFO
22h 47m1 stop
JetBlue Logo
10:35 am - 1:30 pmSFO-GYE
24h 55m1 stop
$455JetBlue
Find Deal
Fri, Oct 17 - Fri, Oct 24
LATAM Airlines Logo
5:04 pm - 10:34 amGYE-SFO
19h 30m2 stops
LATAM Airlines Logo
6:10 am - 10:23 pmSFO-GYE
14h 13m2 stops
$522LATAM Airlines
Find Deal
Sat, Sep 13 - Wed, Oct 15
Avianca Logo
6:25 pm - 12:35 pmGYE-SFO
20h 10m2 stops
Avianca Logo
12:05 am - 10:40 pmSFO-GYE
20h 35m2 stops
$523Avianca
Find Deal
Sat, Sep 13 - Mon, Oct 6
Avianca Logo
4:15 am - 10:45 pmGYE-SFO
20h 30m2 stops
Avianca Logo
12:05 am - 5:20 pmSFO-GYE
15h 15m2 stops
$528Avianca
Find Deal
Thu, Oct 9 - Thu, Oct 16
Avianca Logo
6:25 pm - 10:45 pmGYE-SFO
30h 20m2 stops
Avianca Logo
2:20 pm - 2:05 amSFO-GYE
9h 45m1 stop
$533Avianca
Find Deal
Sun, Sep 14 - Tue, Oct 7
JetBlue Logo
2:40 pm - 11:16 pmGYE-SFO
34h 36m1 stop
JetBlue Logo
11:20 pm - 1:30 pmSFO-GYE
12h 10m1 stop
$534JetBlue
Find Deal
Wed, Oct 15 - Fri, Oct 24
United Airlines Logo
2:54 pm - 9:10 pmGYE-SFO
32h 16m1 stop
United Airlines Logo
12:43 am - 11:37 pmSFO-GYE
20h 54m2 stops
$549United Airlines
Find Deal
Thu, Oct 16 - Wed, Oct 22
United Airlines Logo
12:17 pm - 5:46 pmGYE-SFO
31h 29m2 stops
United Airlines Logo
12:43 am - 11:37 pmSFO-GYE
20h 54m2 stops
$555United Airlines
Find Deal
Tue, Sep 30 - Mon, Oct 6
Copa Airlines Logo
6:05 am - 11:25 pmGYE-SFO
19h 20m1 stop
Copa Airlines Logo
1:31 am - 1:46 pmSFO-GYE
10h 15m1 stop
$597Copa Airlines
Find Deal
Sat, Sep 13 - Mon, Oct 6

JetBlue flights from Guayaquil to San Francisco

Our best JetBlue deals on Guayaquil to San Francisco flight tickets
JetBlue
Oct 17
GYE2:40 pmGuayaquil Jose Joaquin de Olmedo
22h 47m
1 stop
SFO11:27 amSan Francisco
Oct 24
SFO10:35 amSan Francisco
24h 55m
1 stop
GYE1:30 pmGuayaquil Jose Joaquin de Olmedo
$425
Find similar
JetBlue
Oct 17
GYE2:40 pmGuayaquil Jose Joaquin de Olmedo
22h 47m
1 stop
SFO11:27 amSan Francisco
Oct 24
SFO10:35 amSan Francisco
24h 55m
1 stop
GYE1:30 pmGuayaquil Jose Joaquin de Olmedo
$455
Find similar
JetBlue
Oct 15
GYE2:40 pmGuayaquil Jose Joaquin de Olmedo
34h 36m
1 stop
SFO11:16 pmSan Francisco
Oct 24
SFO11:20 pmSan Francisco
12h 10m
1 stop
GYE1:30 pmGuayaquil Jose Joaquin de Olmedo
$534
Find similar

Avianca flights from Guayaquil to San Francisco

Our best Avianca deals on Guayaquil to San Francisco flight tickets
Avianca
Sep 7
GYE3:35 amGuayaquil Jose Joaquin de Olmedo
21h 10m
2 stops
SFO10:45 pmSan Francisco
Mar 7
SFO1:35 amSan Francisco
20h 30m
2 stops
GYE1:05 amGuayaquil Jose Joaquin de Olmedo
$504
Find similar
Avianca
Sep 5
GYE3:15 amGuayaquil Jose Joaquin de Olmedo
21h 30m
1 stop
SFO10:45 pmSan Francisco
Sep 10
SFO2:20 pmSan Francisco
9h 45m
1 stop
GYE2:05 amGuayaquil Jose Joaquin de Olmedo
$510
Find similar
Avianca
Sep 9
GYE6:25 pmGuayaquil Jose Joaquin de Olmedo
20h 10m
2 stops
SFO12:35 pmSan Francisco
Sep 14
SFO2:20 pmSan Francisco
19h 00m
2 stops
GYE11:20 amGuayaquil Jose Joaquin de Olmedo
$513
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Guayaquil to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 3, 2025.
Use the filters below to find and compare flights from Guayaquil to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 10/17

2:40 pm-11:27 am

1 stop22h 47m

San Francisco

Fri 10/24

10:35 am-1:30 pm

1 stop24h 55m

$425

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Fri 10/17

2:40 pm-11:27 am

1 stop22h 47m

San Francisco

Fri 10/24

10:35 am-1:30 pm

1 stop24h 55m

$455

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sat 9/13

5:04 pm-10:34 am

2 stops19h 30m

San Francisco

Wed 10/15

6:10 am-10:23 pm

2 stops14h 13m

$522

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sat 9/13

6:25 pm-12:35 pm

2 stops20h 10m

San Francisco

Mon 10/6

12:05 am-10:40 pm

2 stops20h 35m

$523

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Thu 10/9

4:15 am-10:45 pm

2 stops20h 30m

San Francisco

Thu 10/16

12:05 am-5:20 pm

2 stops15h 15m

$528

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sun 9/14

6:25 pm-10:45 pm

2 stops30h 20m

San Francisco

Tue 10/7

2:20 pm-2:05 am

1 stop9h 45m

$533

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Wed 10/15

2:40 pm-11:16 pm

1 stop34h 36m

San Francisco

Fri 10/24

11:20 pm-1:30 pm

1 stop12h 10m

$534

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Thu 10/16

2:54 pm-9:10 pm

1 stop32h 16m

San Francisco

Wed 10/22

12:43 am-11:37 pm

2 stops20h 54m

$549

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Tue 9/30

12:17 pm-5:46 pm

2 stops31h 29m

San Francisco

Mon 10/6

12:43 am-11:37 pm

2 stops20h 54m

$555

GuayaquilSan Francisco

GYE - SFO

GYESFO

Guayaquil Jose Joaquin de Olmedo

Sat 9/13

6:05 am-11:25 pm

1 stop19h 20m

San Francisco

Mon 10/6

1:31 am-1:46 pm

1 stop10h 15m

$597

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to San Francisco from

How to get the cheapest flight ticket from Guayaquil to San Francisco

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to San Francisco?

If you aren’t able to travel to San Francisco during the month of November, then flying in June is also cheap. Prices for this month can be found on momondo for an average of $541.

What is the cheapest day to depart on your flight to San Francisco?

The cheapest day to depart from Guayaquil to San Francisco is on a Monday when prices can be found for as low as $358. The most expensive day to fly to San Francisco is Friday, with ticket prices averaging around $670.

What is the cheapest time of day to depart on your flight to San Francisco?

Our data shows that the cheapest Guayaquil to San Francisco flights are usually those with departure times at noon. Our users have found flights to San Francisco at noon for as low as $538. Flights in the morning are often more expensive with an average ticket price of $596.

How far in advance should I book a flight to San Francisco?

You are more likely to see cheaper flights to San Francisco from Guayaquil when booking weeks ahead of your departure date. In general, you can expect to find flights to San Francisco for around $569 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to San Francisco from Guayaquil for as low as $325 on momondo.

Can stopping save me money on Guayaquil to San Francisco flights?

You could potentially save up to 5% on your flight if you consider stops on a Guayaquil to San Francisco flight.

How have Guayaquil to San Francisco flight prices changed over time?

As of September 2025, prices for Guayaquil to San Francisco flights are approximately 7% cheaper when compared to flights at the same time last year.

When to book flights from Guayaquil to San Francisco

Are you open to changing your travel dates? Check out the ideal times to fly from Guayaquil to San Francisco according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Guayaquil to San Francisco (GYE to SFO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Guayaquil to San Francisco

Direct flights

None
There are no direct flights from Guayaquil to San Francisco. There are no popular flight routes from Guayaquil to San Francisco.
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  • How far is Guayaquil Jose Joaquin de Olmedo to San Francisco by plane?

    A flight from Guayaquil Jose Joaquin de Olmedo to San Francisco will travel around 3869.7 mi. 10h 45m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to San Francisco Airport?

    Prices for flights from Guayaquil Jose Joaquin de Olmedo Airport to San Francisco Airport are updated daily.

  • How many operators does momondo search for flights from Guayaquil Jose Joaquin de Olmedo Airport to San Francisco Airport?

  • How old do you have to be to fly from Guayaquil Jose Joaquin de Olmedo Airport to San Francisco Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Guayaquil Jose Joaquin de Olmedo Airport to San Francisco Airport.

  • What documentation or ID do you need to fly to San Francisco Airport?

    The required travel and health documents for your San Francisco Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at San Francisco Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Guayaquil to San Francisco?

Best airlines flying from Guayaquil to San Francisco

Compare and see reviews for airlines that fly from Guayaquil to San Francisco with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $256Free CancellationRating
6.7
2,427 reviews
Search Avianca flights
Copa AirlinesPriceFrom $297Free CancellationRating
7.6
1,525 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $301Free CancellationRating
7.4
8,937 reviews
Search United Airlines flights

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
Carmel-by-the-Sea
Modesto
Sonoma
Calistoga
Hayward
Bodega Bay
Roseville
Santa Clara
Big Sur
Daly City
Fremont
Berkeley
Walnut Creek
Half Moon Bay
Vallejo
South San Francisco
Redwood City
Pacific Grove
Pacifica

Why use momondo?

Why should I use momondo to find a flight deal from Guayaquil to San Francisco?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to San Francisco from Guayaquil.

Can I find flights from Guayaquil to San Francisco with flexible booking policies on momondo?

All flight searches from Guayaquil to San Francisco on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Guayaquil to San Francisco?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to San Francisco from Guayaquil.

I’m not ready to book a flight from Guayaquil to San Francisco right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Guayaquil to San Francisco flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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